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The Role Of Gender In Single Vs Married Individuals With Bipolar Disorder., Daniel Z Lieberman, Suena H Massey, Frederick K Goodwin 2010 Himmelfarb Health Sciences Library, The George Washington University

The Role Of Gender In Single Vs Married Individuals With Bipolar Disorder., Daniel Z Lieberman, Suena H Massey, Frederick K Goodwin

Psychiatry and Behavioral Sciences Faculty Publications

BACKGROUND: Despite the importance of marriage as a source of social support, it has been largely neglected in studies of bipolar disorder; and differential effects on men and women have not been explored.

METHODS: Data on episodes of depression, mania, and mixed states were collected for the previous 2 years from a sample of 282 bipolar individuals using the National Institute of Mental Health Life Chart Methodology.

RESULTS: Effects unique to women included the following: Bipolar women were significantly more likely to be married. Married women had fewer episodes of depression during the past 2 years than never-married women, and ...


A Randomized Comparison Of Online And Paper Mood Charts For People With Bipolar Disorder., Daniel Z Lieberman, Tammas F Kelly, Lanny Douglas, Frederick K Goodwin 2010 Himmelfarb Health Sciences Library, The George Washington University

A Randomized Comparison Of Online And Paper Mood Charts For People With Bipolar Disorder., Daniel Z Lieberman, Tammas F Kelly, Lanny Douglas, Frederick K Goodwin

Psychiatry and Behavioral Sciences Faculty Publications

BACKGROUND: Longitudinal mood instability is the essential feature of bipolar disorder, however most rating scales are cross sectional in nature, and focus on acute symptoms. By contrast, the NIMH Life Chart Methodology (LCM) characterizes in detail the severity, duration, and frequency of mood episodes. Adherence to daily rating, however, tends to be low. In this study an online version of the LCM, designed to enhance adherence, was compared to the standard paper version.

METHODS: Patients from a mood disorders specialty clinic were randomized to the standard LCM or an online, open-source adaptation. The online version used hypertext links embedded in ...


Desvenlafaxine In Major Depressive Disorder: An Evidence-Based Review Of Its Place In Therapy., Daniel Z Lieberman, Suena H Massey 2010 Himmelfarb Health Sciences Library, The George Washington University

Desvenlafaxine In Major Depressive Disorder: An Evidence-Based Review Of Its Place In Therapy., Daniel Z Lieberman, Suena H Massey

Psychiatry and Behavioral Sciences Faculty Publications

INTRODUCTION: Desvenlafaxine, the active metabolite of venlafaxine, is a serotonin norepinephrine reuptake inhibitor (SNRI) recently approved for the treatment of major depressive disorder. It is one of only three medications in this class available in the United States.

AIMS: The objective of this article is to review the published evidence for the safety and efficacy of desvenlafaxine, and to compare it to other antidepressants to delineate its role in the treatment of depression.

EVIDENCE REVIEW: At the recommended dose of 50 mg per day the rate of response and remission was similar to other SNRIs, as was the adverse effect ...


Terrorism And Health: The Responsibility Of Intellectuals, Haider A. Naqvi, Syed Faraz Kazim, Shafqat Huma 2010 Aga Khan University

Terrorism And Health: The Responsibility Of Intellectuals, Haider A. Naqvi, Syed Faraz Kazim, Shafqat Huma

Department of Psychiatry

No abstract provided.


Mental Illness: Understanding The Impact On Families And How To Help, Joanne Nicholson 2010 University of Massachusetts Medical School

Mental Illness: Understanding The Impact On Families And How To Help, Joanne Nicholson

Implementation Science and Practice Advances Research Center Publications

Abstract: Family is the context where mental health recovery takes place. Mental health services need to take a whole-of-family approach when working with people with a mental illness. Supporting people with a mental illness in their family roles actually improved the mental health outcomes of people participating in their programs.


Supporting Parents: Multi-Needs And The Need For Multi-Institutions’ Coordination Of Supports, Joanne Nicholson 2010 University of Massachusetts Medical School

Supporting Parents: Multi-Needs And The Need For Multi-Institutions’ Coordination Of Supports, Joanne Nicholson

Implementation Science and Practice Advances Research Center Publications

Summary: Family members are likely to have multiple and overlapping needs & roles – individuals with mental illness, carers & siblings. There are many opportunities & strategies for intervention. The best care requires the engagement of multiple stakeholders working in partnership.


Helping Families— Shifting The Emphasis, Joanne Nicholson 2010 University of Massachusetts Medical School

Helping Families— Shifting The Emphasis, Joanne Nicholson

Implementation Science and Practice Advances Research Center Publications

Abstract: Family members are likely to have multiple and overlapping needs & roles – individuals with mental illness and carers. There are many opportunities & strategies for intervention. The best care requires the engagement of multiple stakeholders.


Methodological Considerations For Treatment Trials For Persons With Borderline Personality Disorder, Mary C. Zanarini, Barbara Stanley, Donald W. Black, John C. Markowitz, Marianne Goodman, Paul Pilkonis, Thomas R. Lynch, Kenneth Levy, Peter Fonagy, Martin Bohus, Joan Farrell, Charles A. Sanislow 2010 Harvard Medical School

Methodological Considerations For Treatment Trials For Persons With Borderline Personality Disorder, Mary C. Zanarini, Barbara Stanley, Donald W. Black, John C. Markowitz, Marianne Goodman, Paul Pilkonis, Thomas R. Lynch, Kenneth Levy, Peter Fonagy, Martin Bohus, Joan Farrell, Charles A. Sanislow

Charles A. Sanislow, Ph.D.

BACKGROUND: The National Institute of Mental Health convened an international group of experts to examine the conduct of treatment trials for persons with borderline personality disorder (BPD). The rapid growth of treatment research had led to the recognition that investigators face unique methodological issues with these challenging patients.

METHODS: Conference members reviewed critical aspects of psychotherapy and pharmacotherapy trial design for patients with BPD.

RESULTS: This article summarizes discussions held on March 17-18, 2005.

CONCLUSION: This paper addresses the most pressing issues in sample selection and trial design pertaining to BPD; issues that have bedeviled both investigators submitting applications and ...


State Effects Of Major Depression On The Assessment Of Personality And Personality Disorder, Leslie C. Morey, M. Tracie Shea, John C. Markowitz, Robert L. Stout, Christopher J. Hopwood, John G. Gunderson, Carlos M. Grilo, Thomas H. McGlashan, Shirley Yen, Charles A. Sanislow, Andrew E. Skodol 2010 Texas A & M University - College Station

State Effects Of Major Depression On The Assessment Of Personality And Personality Disorder, Leslie C. Morey, M. Tracie Shea, John C. Markowitz, Robert L. Stout, Christopher J. Hopwood, John G. Gunderson, Carlos M. Grilo, Thomas H. Mcglashan, Shirley Yen, Charles A. Sanislow, Andrew E. Skodol

Charles A. Sanislow, Ph.D.

OBJECTIVE: The authors sought to determine whether personality disorders diagnosed during a depressive episode have long-term outcomes more typical of those of other patients with personality disorders or those of patients with noncomorbid major depression.

METHOD: The authors used 6-year outcome data collected from the multisite Collaborative Longitudinal Personality Disorders Study (CLPS). Diagnoses and personality measures gathered from the study cohort at the index assessment using interview and self-report methods were associated with symptomatic, functional, and personality measures at 6-year follow-up. Of 668 patients initially recruited to the CLPS, 522 were followed for 6 years. All participants had either a ...


Correlation Of Measures Of Psychotherapy Competency In Psychiatry Residents, Julia Matthews-Bellinger, Sheldon Benjamin, Mohit Chauhan, Mary L. Zanetti 2010 University of Massachusetts Medical School

Correlation Of Measures Of Psychotherapy Competency In Psychiatry Residents, Julia Matthews-Bellinger, Sheldon Benjamin, Mohit Chauhan, Mary L. Zanetti

Psychiatry Publications

This current study had two goals: 1. To examine the changes in various performance measures
as residents progress through psychotherapy training
2. To explore correlations among various measures of psychotherapy
competence Conclusions:

  • Resident self-assessment does not appear to reflect competence
    as assessed by supervisors, or knowledge as assessed by objective
    tests.
  • Global supervisor evaluations do not appear to reliably measure
    competence.
  • Standardized supervisor assessment instruments are needed.
  • Further work is needed to develop reliable, valid measures of
    competency.


Emerging Issues In Adolescent Healthcare : An Urgent Call For Action, Waris Qidwai Dr, Tabinda Ashfaq Ashfaq 2010 Aga Khan University Karachi

Emerging Issues In Adolescent Healthcare : An Urgent Call For Action, Waris Qidwai Dr, Tabinda Ashfaq Ashfaq

Department of Family Medicine

No abstract provided.


International Migration Of Doctors, And Its Impact On Availability Of Psychiatrists In Low And Middle Income Countries, Rachel Jenkins, Robert Kydd, Paul Mullen, Kenneth Thomson, James Sculley, Susan Kuper, Joanna Carroll, Oye Gureje, Simon Hatcher, Sharon Brownie, Christopher Carroll, Sheila Hollins, Mai Luen Wong 2010 King’s College London

International Migration Of Doctors, And Its Impact On Availability Of Psychiatrists In Low And Middle Income Countries, Rachel Jenkins, Robert Kydd, Paul Mullen, Kenneth Thomson, James Sculley, Susan Kuper, Joanna Carroll, Oye Gureje, Simon Hatcher, Sharon Brownie, Christopher Carroll, Sheila Hollins, Mai Luen Wong

School of Nursing & Midwifery, East Africa

Background: Migration of health professionals from low and middle income countries to rich countries is a large scale and long-standing phenomenon, which is detrimental to the health systems in the donor countries. We sought to explore the extent of psychiatric migration.

Methods: In our study, we use the respective professional databases in each country to establish the numbers of psychiatrists currently registered in the UK, US, New Zealand, and Australia who originate from other countries. We also estimate the impact of this migration on the psychiatrist population ratios in the donor countries.

Findings: We document large numbers of psychiatrists currently ...


Attachment-Based Family Therapy For Adolescents With Suicidal Ideation: A Randomized Controlled Trial., Guy S. Diamond, Matthew B. Wintersteen, Gregory K. Brown, Gary M. Diamond, Robert Gallop, Karni Shelef, Suzanne Levy 2010 The Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine

Attachment-Based Family Therapy For Adolescents With Suicidal Ideation: A Randomized Controlled Trial., Guy S. Diamond, Matthew B. Wintersteen, Gregory K. Brown, Gary M. Diamond, Robert Gallop, Karni Shelef, Suzanne Levy

Department of Psychiatry and Human Behavior Faculty Papers

OBJECTIVE: To evaluate whether Attachment-Based Family Therapy (ABFT) is more effective than Enhanced Usual Care (EUC) for reducing suicidal ideation and depressive symptoms in adolescents. METHOD: This was a randomized controlled trial of suicidal adolescents between the ages of 12 and 17, identified in primary care and emergency departments. Of 341 adolescents screened, 66 (70% African American) entered the study for 3 months of treatment. Assessment occurred at baseline, 6 weeks, 12 weeks, and 24 weeks. ABFT consisted of individual and family meetings, and EUC consisted of a facilitated referral to other providers. All participants received weekly monitoring and access ...


Improving Schizophrenia Diagnosis Through Biomarkers: An Upcoming Prospect, Syed Mohammad Asad Zaidi, Abdul Latif Bikak, Rameez-ul Hassan 2010 Aga Khan University

Improving Schizophrenia Diagnosis Through Biomarkers: An Upcoming Prospect, Syed Mohammad Asad Zaidi, Abdul Latif Bikak, Rameez-Ul Hassan

Medical College Documents

No abstract provided.


Cognitive-Behavioral Treatment Of Anxious Youth With Comorbid School Refusal: Clinical Presentation And Treatment Response, Rinad S. Beidas, Sarah A. Crawley, Matthew P. Mychailyszyn, Jonathan S. Comer, Phillip C. Kendall 2010 University of Pennsylvania

Cognitive-Behavioral Treatment Of Anxious Youth With Comorbid School Refusal: Clinical Presentation And Treatment Response, Rinad S. Beidas, Sarah A. Crawley, Matthew P. Mychailyszyn, Jonathan S. Comer, Phillip C. Kendall

Departmental Papers (Psychiatry)

The present study investigated the effectiveness of cognitive-behavioral therapy in youth (N = 27) diagnosed with a principal anxiety disorder and school refusal (SR; denial to attend school or difficulty remaining in school). Scant research examines the effectiveness of cognitive-behavioral therapy for treatment-seeking youth with a primary anxiety disorder and comorbid SR. Effects for youth who completed treatment (N = 12) ranged from d = .61 to 2.27 based on youth- and parent-reported anxiety and depressive symptoms, as well as independently rated global functioning. A discussion of treatment drop-out, a case illustration, and treatment recommendations are provided.


Guidance For Improving Forensic Reports: A Review Of Common Errors, Thomas Grisso 2010 University of Massachusetts Medical School

Guidance For Improving Forensic Reports: A Review Of Common Errors, Thomas Grisso

Psychiatry Publications

This study employed a national sample of forensic reports that had been critiqued by a panel of advanced forensic mental-health practitioners serving as reviewers for the American Board of Forensic Psychology. The study describes all of the discrete types of faults that reviewers encountered in the reports, and then converts them to prescriptive statements to guide forensic report writing. The study also identifies the most frequent report-writing problems in this sample. The results were not intended to describe the quality of forensic reports in the U.S., but rather to offer guidance for improving the quality of forensic reports.


Mission Diversion & Recovery For Traumatized Veterans (Mission Direct Vet): Early Findings And Lessons Learned, Paul P. Christopher, Elizabeth A. Aaker, Amanda Lennox, William H. Fisher, Carl E. Fulwiler, Stephanie W. Hartwell, David Smelson, Debra A. Pinals 2010 University of Massachusetts Medical School

Mission Diversion & Recovery For Traumatized Veterans (Mission Direct Vet): Early Findings And Lessons Learned, Paul P. Christopher, Elizabeth A. Aaker, Amanda Lennox, William H. Fisher, Carl E. Fulwiler, Stephanie W. Hartwell, David Smelson, Debra A. Pinals

Implementation Science and Practice Advances Research Center Publications

MISSION DIRECT VET is a SAMHSA- funded, court based diversion program targeting veterans in Massachusetts with trauma-related mental health and substance use problems. MISSION-DIRECT VET seeks to: Reduce criminal justice involvement Treat mental health, substance abuse and other trauma related symptoms Use a systematic wrap-around model Provide care coordination, peer support and trauma informed services Develop interagency partnerships to serve veterans with co-occurring disorders


The Learning And Working During The Transition To Adulthood Rehabilitation Research And Training Center, Maryann Davis, Jonathan Delman, Marsha Langer Ellison, Charles W. Lidz 2010 University of Massachusetts Medical School

The Learning And Working During The Transition To Adulthood Rehabilitation Research And Training Center, Maryann Davis, Jonathan Delman, Marsha Langer Ellison, Charles W. Lidz

Implementation Science and Practice Advances Research Center Publications

Research and dissemination activities are singularly focused on developing knowledge for and about developmentally appropriate services that help transition Age Youth and Young Adults (TAYYA) with Serious Mental Health Conditions (SMHC) successfully complete their schooling and training and launch their adult working careers.


Improving Risk Assessment With Suicidal Patients: A Preliminary Evaluation Of The Clinical Utility Of The Scale For Impact Of Suicidality - Management, Assessment And Planning Of Care (Sis-Map), Charles Nelson, Megan Johnston, Amresh Srivastava 2009 The University of Western Ontario

Improving Risk Assessment With Suicidal Patients: A Preliminary Evaluation Of The Clinical Utility Of The Scale For Impact Of Suicidality - Management, Assessment And Planning Of Care (Sis-Map), Charles Nelson, Megan Johnston, Amresh Srivastava

Amresh Srivastava

Although a number of suicide risk assessment tools are available to clinicians, the high levels of suicide still evident in society suggest a clear need for new strategies in order to facilitate the prevention of suicidal behaviors. The present study examined the utilization of a new structured clinical interview called the Scale for Impact of Suicidality Management, Assessment and Planning of Care (SIS-MAP). SIS-MAP ratings were obtained from a group of incoming psychiatric patients over a 6-month period at Regional Mental Health Care, St. Thomas, Ontario. A canonical discriminant function analysis resulted in a total 74.0% of original grouped ...


Developing Constructs For Psychopathology Research: Research Domain Criteria, Charles A. Sanislow, Daniel S. Pine, Kevin J. Quinn, Michael J. Kozak, Marjorie A. Garvey, Robert K. Heinssen, Philip S. Wang, Bruce N. Cuthbert 2009 Wesleyan University

Developing Constructs For Psychopathology Research: Research Domain Criteria, Charles A. Sanislow, Daniel S. Pine, Kevin J. Quinn, Michael J. Kozak, Marjorie A. Garvey, Robert K. Heinssen, Philip S. Wang, Bruce N. Cuthbert

Charles A. Sanislow, Ph.D.

There exists a divide between findings from integrative neuroscience and clinical research focused on mechanisms of psychopathology. Specifically, a clear correspondence does not emerge between clusters of complex clinical symptoms and dysregulated neurobiological systems, with many apparent redundancies. For instance, many mental disorders involve multiple disruptions in putative mechanistic factors (e.g., excessive fear, deficient impulse control), and different disrupted mechanisms appear to play major roles in many disorders. The Research Domain Criteria (RDoC) framework is a heuristic to facilitate the incorporation of behavioral neuroscience in the study of psychopathology. Such integration might be achieved by shifting the central research ...


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