Psychiatry Commons^™

Interpersonal Violence And Suicidality Among Former Child Soldiers And War-Exposed Civilian Children In Nepal., Anvita Bhardwaj, Christine Bourey, Sauharda Rai, Ramesh Prasad Adhikari, Carol M Worthman, Brandon A Kohrt

Psychiatry and Behavioral Sciences Faculty Publications

Background: Suicide risk reduction is crucial for 15-29-year-old youth, who account for 46% of suicide deaths in low- and middle-income countries. Suicide predictors in high-resource settings, specifically depression, do not adequately predict suicidality in these settings. We explored if interpersonal violence (IPV) was associated with suicidality, independent of depression, in Nepal.

Methods: A longitudinal cohort of child soldiers and matched civilian children, enrolled in 2007 after the People's War in Nepal, were re-interviewed in 2012. The Depression Self-Rating Scale and Composite International Diagnostic Interview assessed depression and suicidality, respectively. Non-verbal response cards were used to capture experiences of sexual and …

Neural Correlates Of Taste Reactivity In Autism Spectrum Disorder., Jason A Avery, John E Ingeholm, Sophie Wohltjen, Meghan Collins, Cameron D Riddell, Stephen J Gotts, Lauren Kenworthy, Gregory L Wallace, W Kyle Simmons, Alex Martin

Psychiatry and Behavioral Sciences Faculty Publications

Selective or 'picky' eating habits are common among those with autism spectrum disorder (ASD). These behaviors are often related to aberrant sensory experience in individuals with ASD, including heightened reactivity to food taste and texture. However, very little is known about the neural mechanisms that underlie taste reactivity in ASD. In the present study, food-related neural responses were evaluated in 21 young adult and adolescent males diagnosed with ASD without intellectual disability, and 21 typically-developing (TD) controls. Taste reactivity was assessed using the Adolescent/Adult Sensory Profile, a clinical self-report measure. Functional magnetic resonance imaging was used to evaluate hemodynamic responses …

Erratum: Specificity Of Incident Diagnostic Outcomes In Patients At Clinical High Risk For Psychosis (Schizophrenia Bulletin (2015) 41 (1066-1075) Doi: 10.1093/Schbul/Sbv091), J. R. Webb, J. Addington, D. O. Perkins, C. E. Bearden, K. S. Cadenhead, T. D. Cannon, B. A. Cornblatt, R. K. Heinssen, L. J. Seidman, S. W. Woods, +4 Additional Authors

Journal Articles

© The Author(s) 2018. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. An error in statistical syntax defining baseline disorder led to misidentification of baseline anxiety disorder in five cases in one of the two reported samples (PREDICT). NAPLS-1 data and previous publications of PREDICT data were not affected. The error affected rows in Table 1 labeled 'DSM-IV anxiety' and 'Any mood/anx disorder' and rows in Table 3 labeled 'Baseline Anxiety Excluded' and 'Any Baseline Mood/ Anxiety Excluded.' Corrected Tables are shown below with corrected numbers in bold. Tables S1-S5 in the …

Preliminary Findings Of Altered Functional Connectivity Of The Default Mode Network Linked To Functional Outcomes One Year After Pediatric Traumatic Brain Injury, J. A. Stephens, C. F. Salorio, A. D. Barber, S. R. Risen, S. H. Mostofsky, S. J. Suskauer

Journal Articles

© 2018, © 2018 Taylor & Francis. Purpose and Method: This study examined functional connectivity of the default mode network (DMN) and examined brain–behavior relationships in a pilot cohort of children with chronic mild to moderate traumatic brain injury (TBI). Results: Compared to uninjured peers, children with TBI demonstrated less anti-correlated functional connectivity between DMN and right Brodmann Area 40 (BA 40). In children with TBI, more anomalous less anti-correlated) connectivity between DMN and right BA 40 was linked to poorer performance on response inhibition tasks. Conclusion: Collectively, these preliminary findings suggest that functional connectivity between DMN and BA 40 …

Investigation Of Superior Longitudinal Fasciculus Fiber Complexity In Recent Onset Psychosis, P. R. Szeszko, E. T. Tan, A. M. Ulug, P. B. Kingsley, J. A. Gallego, K. Rhindress, A. K. Malhotra, D. G. Robinson, L. Marinelli

Journal Articles

No abstract provided.

Latent Class Cluster Analysis Of Symptom Ratings Identifies Distinct Subgroups Within The Clinical High Risk For Psychosis Syndrome, A. T. Ryan, J. Addington, C. E. Bearden, K. S. Cadenhead, B. A. Cornblatt, D. H. Mathalon, T. H. Mcglashan, D. O. Perkins, L. J. Seidman, E. F. Walker, +3 Additional Authors

Journal Articles

© 2017 The clinical-high-risk for psychosis (CHR-P) syndrome is heterogeneous in terms of clinical presentation and outcomes. Identifying more homogenous subtypes of the syndrome may help clarify its etiology and improve the prediction of psychotic illness. This study applied latent class cluster analysis (LCCA) to symptom ratings from the North American Prodrome Longitudinal Studies 1 and 2 (NAPLS 1 and 2). These analyses produced evidence for three to five subgroups within the CHR-P syndrome. Differences in negative and disorganized symptoms distinguished among the subgroups. Subgroup membership was found to predict conversion to psychosis. The authors contrast the methods employed within …

A Collaborative, Network-Based Approach To Advance Women's Depression Research In The United States: Preliminary Findings, H. A. Flynn, C. Spino, C. Guille, K. M. Deligiannidis, P. Maki, J. Jahnke, K. L. Rosenblum, C. N. Epperson, S. J. Weiss

Journal Articles

No abstract provided.

Improved Estimation Of Subject-Level Functional Connectivity Using Full And Partial Correlation With Empirical Bayes Shrinkage, A. F. Mejia, M. B. Nebel, A. D. Barber, A. S. Choe, J. J. Pekar, B. S. Caffo, M. A. Lindquist

Journal Articles

© 2018 Reliability of subject-level resting-state functional connectivity (FC) is determined in part by the statistical techniques employed in its estimation. Methods that pool information across subjects to inform estimation of subject-level effects (e.g., Bayesian approaches) have been shown to enhance reliability of subject-level FC. However, fully Bayesian approaches are computationally demanding, while empirical Bayesian approaches typically rely on using repeated measures to estimate the variance components in the model. Here, we avoid the need for repeated measures by proposing a novel measurement error model for FC describing the different sources of variance and error, which we use to perform …

Smri Biomarkers Predict Electroconvulsive Treatment Outcomes: Accuracy With Independent Data Sets, R. Jiang, C. C. Abbott, T. Jiang, Y. Du, R. Espinoza, K. L. Narr, B. Wade, M. Argyelan, G. Petrides, V. D. Calhoun, +6 Additional Authors

Journal Articles

No abstract provided.

The Evolution Of Cultural Psychiatry, R. S. Shim

Journal Articles

No abstract provided.

Stress-Dependent Association Between Polygenic Risk For Schizophrenia And Schizotypal Traits In Young Army Recruits, A. Hatzimanolis, D. Avramopoulos, D. E. Arking, A. Moes, P. Bhatnagar, T. Lencz, A. K. Malhotra, S. G. Giakoumaki, P. Roussos, N. C. Stefanis, +2 Additional Authors

Journal Articles

No abstract provided.

Efficacy Of Guided Icbt For Depression And Mediation Of Change By Cognitive Skill Acquisition, N. R. Forand, J. G. Barnett, D. R. Strunk, M. U. Hindiyeh, J. E. Feinberg, J. R. Keefe

Journal Articles

No abstract provided.

Measuring Cognition And Function In The Preclinical Stage Of Alzheimer's Disease, S. Weintraub, M. C. Carrillo, S. T. Farias, T. E. Goldberg, J. A. Hendrix, J. Jaeger, D. S. Knopman, J. B. Langbaum, D. C. Park, C. Randolph, +9 Additional Authors

Journal Articles

© 2018 The Authors The Alzheimer's Association's Research Roundtable met in November 2016 to explore how best to measure changes in cognition and function in the preclinical stage of Alzheimer's disease. This review will cover the tools and instruments currently available to identify populations for prevention trials, and measure subtle disease progression in the earliest stages of Alzheimer's disease, and will include discussions of suitable cognitive, behavioral, functional, composite, and biological endpoints for prevention trials. Current prevention trials are reviewed including TOMMOROW, Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease Trial, the Alzheimer's Prevention Initiative Generation Study, and the Anti-Amyloid Treatment …

Predictors Of Aggression In 3.322 Patients With Affective Disorders And Schizophrenia Spectrum Disorders Evaluated In An Emergency Department Setting, E. A. Blanco, L. M. Duque, V. Rachamallu, E. Yuen, J. M. Kane, J. A. Gallego

Journal Articles

No abstract provided.

The Genetics Of Endophenotypes Of Neurofunction To Understand Schizophrenia (Genus) Consortium: A Collaborative Cognitive And Neuroimaging Genetics Project, G. A. Blokland, E. C. Del Re, R. I. Mesholam-Gately, J. Jovicich, J. Trampush, M. S. Keshavan, L. E. Delisi, A. K. Malhotra, T. Lencz, T. L. Petryshen, +64 Additional Authors

Journal Articles

No abstract provided.

Identifying Patients And Clinical Scenarios For Use Of Long-Acting Injectable Antipsychotics - Expert Consensus Survey Part I, M. Sajatovic, R. Ross, S. N. Legacy, C. U. Correll, J. M. Kane, F. Dibiasi, H. Fitzgerald, M. Byerly

Journal Articles

No abstract provided.

Networks Of Blood Proteins In The Neuroimmunology Of Schizophrenia, C. D. Jeffries, D. O. Perkins, M. Fournier, K. Q. Do, M. Cuenod, I. Khadimallah, E. Domenici, J. Addington, B. A. Cornblatt, S. W. Woods, +8 Additional Authors

Journal Articles

© 2018 The Author(s). Levels of certain circulating cytokines and related immune system molecules are consistently altered in schizophrenia and related disorders. In addition to absolute analyte levels, we sought analytes in correlation networks that could be prognostic. We analyzed baseline blood plasma samples with a Luminex platform from 72 subjects meeting criteria for a psychosis clinical high-risk syndrome; 32 subjects converted to a diagnosis of psychotic disorder within two years while 40 other subjects did not. Another comparison group included 35 unaffected subjects. Assays of 141 analytes passed early quality control. We then used an unweighted co-expression network analysis …

Erratum To: Specificity Of Incident Diagnostic Outcomes In Patients At Clinical High Risk For Psychosis, J. R. Webb, J. Addington, D. O. Perkins, C. E. Bearden, K. S. Cadenhead, T. D. Cannon, B. A. Cornblatt, R. K. Heinssen, L. J. Seidman, S. W. Woods, +4 Additional Authors

Journal Articles

© The Author(s) 2018. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. An error in statistical syntax defining baseline disorder led to misidentification of baseline anxiety disorder in five cases in one of the two reported samples (PREDICT). NAPLS-1 data and previous publications of PREDICT data were not affected. The error affected rows in Table 1 labeled 'DSM-IV anxiety' and 'Any mood/anx disorder' and rows in Table 3 labeled 'Baseline Anxiety Excluded' and 'Any Baseline Mood/ Anxiety Excluded.' Corrected Tables are shown below with corrected numbers in bold. Tables S1-S5 in the …

A Longitudinal Human Phantom Reliability Study Of Multi-Center T1-Weighted, Dti, And Resting State Fmri Data, C. Hawco, J. D. Viviano, S. Chavez, E. W. Dickie, N. Calarco, P. Kochunov, M. Argyelan, J. A. Turner, A. K. Malhotra, A. N. Voineskos, +1 Additional Author

Journal Articles

© 2018 Multi-center MRI studies can enhance power, generalizability, and discovery for clinical neuroimaging research in brain disorders. Here, we sought to establish the utility of a clustering algorithm as an alternative to more traditional intra-class correlation coefficient approaches in a longitudinal multi-center human phantom study. We completed annual reliability scans on ‘travelling human phantoms’. Acquisitions across sites were harmonized prospectively. Twenty-seven MRI sessions were available across four participants, scanned on five scanners, across three years. For each scan, three metrics were extracted: cortical thickness (CT), white matter fractional anisotropy (FA), and resting state functional connectivity (FC). For each metric, …

The Early Psychosis Screener (Eps): Quantitative Validation Against The Sips Using Machine Learning, B. B. Brodey, R. R. Girgis, O. Favorov, J. Addington, D. O. Perkins, C. E. Bearden, S. W. Woods, E. F. Walker, B. A. Cornblatt, I. S. Brodey, +3 Additional Authors

Journal Articles

No abstract provided.