Pediatrics Commons^™

Parental Perception Of Improvement In Prelinguistic Skills In Kids With Autism In Two Months Of Goal Directed Cognitive Approach, Ratnapriya Chowdhry, Santosh Kondekar, Surbhi Rathi, Abhinaya V, Tasneem Motiwala

Digital Journal of Clinical Medicine

The study aimed to assess the parental perception of improvement in prelinguistic skills in children with Autism Spectrum disorder [ASD] after 1 and 2 months of Goal Directed Cognitive Approach. This was assessed by a questionnaire filled by parents of 26 consecutive ASD kids at a neurodevelopmental center. Parents were asked to rate these skills on a Likert scale of 1-5 before and after 1 month and 2 months of GDCA to check for any improvement. 69% of ASD kids were boys. Mean age at presentation was 2.6 years. The children were subjected to GDCA for an average duration of …

Multi-Dose Enteral L-Citrulline Administration In Premature Infants At Risk Of Developing Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia, Candice D. Fike, Judy L. Aschner, Charul Avachat, Angela K. Birnbaum, Catherine M.T. Sherwin

Pediatrics Faculty Publications

Objective: Information is needed to guide the design of randomized controlled trials (RCTs) evaluating L-citrulline therapy for premature infants with pulmonary hypertension associated with bronchopulmonary dysplasia (BPD-PH). Based on our single-dose pharmacokinetic study, we evaluated the ability of a multi-dose enteral L-citrulline strategy to achieve a target trough steady-state L-citrulline plasma concentration and its tolerability in premature infants. Study design: Plasma L-citrulline concentrations were measured in six premature infants receiving 60 mg/kg L-citrulline every 6 h for 72 h before the first and last L-citrulline doses. L-citrulline concentrations were compared to concentration-time profiles from our previous study. Results: Target trough …

Association Between Gallstone Disease And Kidney Stone Disease: A Systematic Review And Meta-Analysis, Faramarz Beigi, Alizamen Salehifard Jouneghani, Sae Heari-Soureshjani, Catherine M.T. Sherwin, Ghorbanali Rahimian

Pediatrics Faculty Publications

Background and aims: Gallstone disease (GSD) and kidney stone disease (KSD) have increased due to lifestyle in recent decades. This systematic review and meta-analysis aimed to investigate the association between these two diseases. Methods: A comprehensive electronic database search was conducted before August 25, 2024. This systematic review and meta-analysis included observational studies. The meta-analysis employed a random-effects model to compute the overall summary estimates of the association between GSD and KSD using risk ratios with 95% confidence intervals (CIs) as the primary measure of the effect size. Heterogeneity was evaluated using chi-square tests, the I² statistic, and forest plots. …

Developmental Profile Of Filipino Children Born During The Sars-Cov-2 Pandemic: Pilot Study, Angel Belle Dy, Michelle Alexandra Edillon, Mikhaela Francesca Marietta A. Malonzo, Glenda Darlene Garcia, Alane Blythe C. Dy, Clarisse Joyce S. Espiritu, Ma Bianca Carmela Aquino, Shannen Louise T. So, Nina Linly D. Capulong, Rizza Victoria C. Dagal, Lourdes Bernadette Tanchanco

Ateneo School of Medicine and Public Health Publications

Objective

The Philippines experienced one of the longest restriction periods during the COVID-19 pandemic. This study aimed to provide a developmental profile of 18-25 month-old children and identify factors associated with their development during their early years being born and raised during the pandemic.

Methods

The study population was recruited through convenience sampling among families living in proximity to the daycare centers in Cainta, Rizal, Philippines. 116 children qualified to participate and underwent developmental screening using the Early Childhood Care and Development (ECCD) Checklist and their parents were interviewed related to demographic and social factors.

Results

The mean score of …

Post-Discharge Malaria Chemoprevention In Children Admitted With Severe Anaemia In Malaria-Endemic Settings In Africa: A Systematic Review And Individual Patient Data Meta-Analysis Of Randomised Controlled Trials, Kamija Phiri, Carole Khairallah, Titus Kwambai, Kalifa Bojang, Aggrey Dhabangi, Robert Opoka, Richard Idro, Kasia Stepniewska, Michael Boele Van Hensbroek, Chandy C John

Paediatrics and Child Health, East Africa

Background: Severe anaemia is associated with high in-hospital mortality among young children. In malaria-endemic areas, surviving children also have an increased risk of mortality or readmission after hospital discharge. We conducted a systematic review and individual patient data meta-analysis to determine the efficacy of monthly post-discharge malaria chemoprevention in children recovering from severe anaemia.

Methods: This analysis was conducted according to PRISMA-IPD guidelines. We searched multiple databases on Aug 28, 2023, without date or language restrictions, for randomised controlled trials comparing monthly post-discharge malaria chemoprevention with placebo or standard of care among children (agedyears) admitted with severe anaemia in malaria-endemic …

Association Of Maternal Prenatal Copper Concentration With Gestational Duration And Preterm Birth: A Multicountry Meta-Analysis Author Links Open Overlay Panel., Nagendra Monangi, Huan Xu, Yue-Mei Fan, Rasheeda Khanam, Waqasuddin Khan, Saikat Deb, Jesmin Pervin, Joan Price, Lovejeet Kaur, R. Ochieng

Paediatrics and Child Health, East Africa

Background: Copper (Cu), an essential trace mineral regulating multiple actions of inflammation and oxidative stress, has been implicated in risk for preterm birth (PTB).

Objectives: This study aimed to determine the association of maternal Cu concentration during pregnancy with PTB risk and gestational duration in a large multicohort study including diverse populations.

Methods: Maternal plasma or serum samples of 10,449 singleton live births were obtained from 18 geographically diverse study cohorts. Maternal Cu concentrations were determined using inductively coupled plasma mass spectrometry. The associations of maternal Cu with PTB and gestational duration were analyzed using …

Quality Improvement To Optimize Pediatric Mri Efficiency In Hospitalized Patients:Improving The Ordering Process And Reducing Time To Mri Completion, Andrew Stack, John Adent, Eric Shaw

South Atlantic Division GME Research Day 2024

No abstract provided.

Recurrent Intussusception In Child Despite Repeated Surgical Correction, Carlos Cordova, Alexandra Lawlor, Tillie Schumann, Sydney Solomon, Lily Wiedrich

East Florida Division GME Research Day 2024

No abstract provided.

The Impact Of Workplace Stressors On Anxiety Levels And Mental Health Among Pediatric Intensive Care Nurses, Kelsey Ericah Ang

Nursing | Student Research Posters

Background: Pediatric Intensive Care Unit (PICU) nurses work in a high-stress environment where they are exposed daily to traumatic situations. The demanding emotional and physical challenges contribute to significant psychological burdens, including increased stress and anxiety. Purpose: The current paper proposes a research design to examine the outcomes of stress, anxiety levels, and mental well-being on PICU nurses when workplace support and structured debriefing sessions take place following a traumatic event. Methods: Participants will be recruited from PICU hospitals in Northern California. Participation will be voluntary, and informed consent will be obtained prior to the study. The selection criteria will …

Unleashing Wellness: Exploring The Impact Of Pet Therapy On Anxiety Reduction, Quality Of Life, And Treatment Adherence In Pediatric Oncology Patients, Karina Brouwer

Nursing | Senior Theses

Pet therapy is a complementary intervention that involves the interaction between a person and animal, with the focus of improving psychological well-being within diverse populations. In particular, children with oncological disorders have increases in anxiety and stress levels, therefore it is imperative to study the impact of animal interventions within this population. This literature critique explores the impact of pet therapy interventions on anxiety, stress, and quality of life perceptions in pediatric oncology patients. This research proposal will investigate how animal therapy interactions within pediatric oncology patients influence their anxiety levels and perceptions of quality of life and how these …

Advancing School Nursing Practice: A Novel Approach To Screening For Gastrointestinal Disorders In Children, Ashley Bunting, Isabella Cavlan

Nursing | Senior Theses

Background: Currently, mandated health screenings in California schools are limited to vision, hearing, and scoliosis; this leaves several other body systems unmonitored during the crucial years of childhood development. One such system is the gastrointestinal (GI) system, which plays a vital role in the normal growth, nutrition status, development, and overall health of children. Objective: By developing and implementing a GI-specific screening tool in the outpatient school setting, this research aims to increase the detection of GI disorders in children. Not only that, but school nurses can use this novel screening tool to promote early diagnosis, intervention, and …

Immunomodulatory Effects Of Modified Colostrum, Whey, And Their Combination With Other Natural Products: Effects On Natural Killer Cells, Xuesheng Han, David Vollmer, Xuefei Yan, Yahong Zhang, Mingfa Zang, Chenfei Zhang, Catherine M.T. Sherwin, Elena Y. Enioutina

Pediatrics Faculty Publications

Objectives Natural killer (NK) cells are important immune system effector cells providing innate defenses against intracellular infections, including viral infections, immune surveillance, and cancer immunoediting. The primary purpose of this study was to investigate whether modified ultra-filtrated colostrum (UC) and hydrolyzed whey (W) products or their combinations with other natural products with reported immunomodulatory properties will stimulate NK cell cytotoxic activity by activation of granzyme B and IFN-γ production. Methods The ability of study products to stimulate the cytotoxic activity of human-purified CD56+ NK cells and the production of granzyme B and IFN-γ by activated NK cells was evaluated in …

Abnormalities In Pharyngeal Arch-Derived Structures In Satb2-Associated Syndrome, Yuri A. Zarate, Katherine Bosanko, Nada Derar, Jennifer L. Fish

Pediatrics Faculty Publications

SATB2-associated syndrome (SAS, glass syndrome, OMIM#612313) is a neurodevelopmental autosomal dominant disorder with frequent craniofacial abnormalities including palatal and dental anomalies. To assess the role of Satb2 in craniofacial development, we analyzed mutant mice at different stages of development. Here, we show that Satb2 is broadly expressed in early embryonic mouse development including the mesenchyme of the second and third arches. Satb2-/- mutant mice exhibit microglossia, a shortened lower jaw, smaller trigeminal ganglia, and larger thyroids. We correlate these findings with the detailed clinical phenotype of four individuals with SAS and remarkable craniofacial phenotypes with one requiring mandibular distraction in …

Importance Of Tropical Medicine, Chia-Chi Angela Fu, A Clinton White, Miguel Cabada, Ryan Northup

Posters

Overviews the importance of tropical medicine to society and global health.

Unleashing Wellness: Exploring The Impact Of Pet Therapy On Anxiety Reduction, Quality Of Life, And Treatment Adherence In Pediatric Oncology Patients, Karina Brouwer

Nursing | Student Research Posters

Pet therapy is a complementary type of therapeutics in which a person and animal have a guided interaction with the purpose of helping someone cope with physical and/or mental illness. Animal-assisted therapy is used in numerous settings and has been shown to reduce stress, lower blood pressure and heart rate, and decrease anxiety and depression (Husson University, 2022). In particular, pediatric oncology patients have enormous amounts of stress in their lives, which leads to increased anxiety and decreased quality of life (Children's Cancer Cause, 2023). While evidence shows that integrating pet therapy in pediatric oncology patients produces significant benefits on …

Effectiveness Of Early Intervention Programs For Children With Autism Spectrum Disorder, Milan Grace Mendoza Baccay

Nursing | Student Research Posters

Background: Autism spectrum disorder is one of the most common developmental disorders, which affects the way a child learns and gains certain skills. Intervention programs aid in the development of these skills and allow children with autism to reach their full potential. Purpose: The following paper examines the effectiveness of early intervention programs on the social, behavior, and cognitive skills for children with autism spectrum disorder. Methods: Participants will be recruited from local schools and community based organizations and their parents will be highly encouraged to participate. They will be separated into two groups: experimental and control. …

Addressing Healthcare Disparities Faced By Aging Down Syndrome Populations, Rhea Mistry

Pitzer Senior Theses

Down syndrome (DS) is a chromosomal genetic condition that impacts the development of the body and brain. The life expectancy of individuals with DS has drastically improved over the decades, increasing from 9 years in 1929 to 25 years in 1983 and further reaching 60 years by 2002. Individuals with DS face a variety of prominent co-occurring health conditions that are subject to change over time, including cognitive, visual, and hearing impairments, sleep apnea, cardiovascular defects, Down syndrome regression disorder, and dementia. Despite this increase in life span, DS is still most familiar to pediatric care providers, resulting in healthcare …

Demographic And Clinical Characteristics Of Venous Thromboembolism In Children, Deogracia Sindoiya Owende

Master of Medicine in Paediatrics and Child Health

Introduction: Venous thromboembolism in children is a cause of significant morbidity and mortality worldwide with an increasing annual incidence. The present study aimed to increase awareness as well as attempt to inform the management of paediatric venous thromboembolism in this setting.

Objective: To describe the demographic and clinical characteristics of venous thromboembolism in children aged one month to 18 years at two tertiary hospitals in Kenya.

Methods: A descriptive retrospective chart review of patients aged one month to 18 years diagnosed with venous thromboembolism between January 2014 and December 2022 in two tertiary hospitals in Kenya was …

Pediatric Advance Life Support, Monique Edwards, Lance Mwangi

Gulf Coast Division GME Research Symposium 2024

No abstract provided.

Evaluating Causes Of Sinus Tachycardia In The Pediatrics Population And Managing In A Primary Care Setting, Guillemette Calderwood

Capstone Showcase

This article’s goal is to fill a gap in research that compares causes of tachycardia in children by appropriately addressing epidemiology, what is physiologically happening with tachycardia, symptoms that may be associated with it, as well as a differential diagnosis. This review specifically discusses positional orthostatic tachycardia syndrome, anxiety, hyperthyroidism, as well as infection. This is important and needed in order to help providers in diagnosing the cause for this common arrhythmia.