Prospects And Limitations Of Improving Skeletal Growth In A Mouse Model Of Spondyloepiphyseal Dysplasia Caused By R992c (P.R1192c) Substitution In Collagen Ii.,
2017
Thomas Jefferson University
Prospects And Limitations Of Improving Skeletal Growth In A Mouse Model Of Spondyloepiphyseal Dysplasia Caused By R992c (P.R1192c) Substitution In Collagen Ii., Machiko Arita, Jolanta Fertala, Cheryl Hou, James Kostas, Andrzej Steplewski, Andrzej Fertala
Department of Orthopaedic Surgery Faculty Papers
Skeletal dysplasias form a group of skeletal disorders caused by mutations in macromolecules of cartilage and bone. The severity of skeletal dysplasias ranges from precocious arthropathy to perinatal lethality. Although the pathomechanisms of these disorders are generally well defined, the feasibility of repairing established aberrant skeletal tissues that developed in the presence of mutant molecules is currently unknown. Here, we employed a validated mouse model of spondyloepiphyseal dysplasia (SED) that enables temporal control of the production of the R992C (p.R1192C) collagen II mutant that causes this disease. Although in our earlier studies we determined that blocking the expression of this …
Orthopaedic Surgeon Density In West Virginia,
2017
Marshall University
Orthopaedic Surgeon Density In West Virginia, Franklin D. Shuler, Grant S. Buchanan, Zachary Sanford, Milad Modarresi, James Timothy Reagan, Kelly Scott, Chad Fisher, Ali Oliashirazi
Marshall Journal of Medicine
Abstract
West Virginia (WV) has many healthcare disparities and access barriers. For bone and joint disorders, WV has some of the highest rates of musculoskeletal problems, including the highest reported rate of adult arthritis in the nation (36.2%). We hypothesized that WV has one of the lowest Orthopaedic surgeon densities in the country, which can negatively impact the delivery of musculoskeletal care. Using the WV Board of Medicine practitioner databank, the Veterans Administration practitioner data, and national Orthopaedic surgeon census data, we demonstrated a considerably low Orthopaedic surgeon density in WV (7.71/100,000 population versus the national average of 8.51/100,000 population) …
Sports Medicine Potpourri,
2017
Thomas Jefferson University
Sports Medicine Potpourri, Marc I. Harwood, Md
Department of Family & Community Medicine Presentations and Grand Rounds
Objectives:
At the conclusion of this talk, the learner will be:
- Thoroughly confused by the whirlwind of information presented
- But...able to delve into any of the topics at greater length when time permits.
Presentation: 52:03
Faculty,
2017
University of New Mexico
Faculty, Unm Department Of Orthopaedic Surgery
UNM Orthopaedic Research Journal
No abstract provided.
Front Matter,
2017
University of New Mexico
Front Matter, Unm Department Of Orthopaedic Surgery
UNM Orthopaedic Research Journal
No abstract provided.
Mid-Level Providers,
2017
University of New Mexico
Mid-Level Providers, Unm Department Of Orthopaedic Surgery
UNM Orthopaedic Research Journal
No abstract provided.
Division Of Research,
2017
University of New Mexico
Division Of Research, Unm Department Of Orthopaedic Surgery
UNM Orthopaedic Research Journal
No abstract provided.
Letter From The Chair,
2017
University of New Mexico
Letter From The Chair, Unm Department Of Orthopaedic Surgery
UNM Orthopaedic Research Journal
No abstract provided.
Letter From The Co-Editors,
2017
University of New Mexico
Letter From The Co-Editors, Unm Department Of Orthopaedic Surgery
UNM Orthopaedic Research Journal
No abstract provided.
Letter From The Residency Director,
2017
University of New Mexico
Letter From The Residency Director, Unm Department Of Orthopaedic Surgery
UNM Orthopaedic Research Journal
No abstract provided.
Value-Based Bundled Repayment In Total Joint Arthroplasty,
2017
University of New Mexico
Value-Based Bundled Repayment In Total Joint Arthroplasty, Michael M. Decker
UNM Orthopaedic Research Journal
The United States continues to spend an unprecedented amount of annual money on healthcare. However, the costs of providing care may not appropriately reflect the quality of care patients are receiving. This is particularly concerning when examining the projected increase in total joint arthroplasty (TJA) procedures over the next few decades, which are expected to increase to nearly 4 million procedures annually. The Center for Medicare and Medicaid Services (CMS) has responded by increasingly shifting reimbursements from the less efficient fee-forservice repayment model to value-based repayment. The Comprehensive Care for Joint Replacement (CJR) bundle payment model has recently been implemented …
Alumni Map,
2017
University of New Mexico
Alumni Map, Unm Department Of Orthopaedic Surgery
UNM Orthopaedic Research Journal
No abstract provided.
Performance-Enhancing Drugs: A Review,
2017
University of New Mexico
Performance-Enhancing Drugs: A Review, G Keith Gill
UNM Orthopaedic Research Journal
Performance-enhancing drugs and substances have been an integral part of athletics and society. The immense popularity and financial compensation associated with success in sports often results in a desire to win at all costs, which stimulates a never-ending appetite for use of ergogenic aids. Athletes have experimented with these substances (ranging from over-the-counter supplements to anabolic-androgenic steroids and beyond) if a possibility of advantage exists, whether scientifically or theoretically supported. As the technology to create new designer drugs becomes more available, the ability to test for the presence of these substances lags slightly behind. The knowledge base of sports-medicine physicians …
Antegrade Nailing Of Femur Shaft Fractures: A Review,
2017
University of New Mexico
Antegrade Nailing Of Femur Shaft Fractures: A Review, Thomas A. Decoster, Shahram Bozorgnia, Samer Kakish
UNM Orthopaedic Research Journal
Rigid intramedullary (IM) nailing is an effective procedure for treating fractures of the femoral shaft. Despite the existence of alternative devices and techniques (eg, unreamed nails, flexible nails, plates, external fixation, and traction), the use of rigid reamed nails has shown excellent healing rates, return of function, alignment, and low complications. This type of nail has been used in an antegrade approach to the entry site of the fracture, resulting in successful treatment. We describe indications, contraindications, and surgical techniques of antegrade IM nailing associated with our personal experience and published results. We provide pearls and pitfalls to assist orthopaedic …
Radiographic And Clinical Evaluation Of Syndesmotic Screws In Treating Injuries Of The Distal Aspect Of The Tibiofibular Syndesmosis,
2017
University of New Mexico
Radiographic And Clinical Evaluation Of Syndesmotic Screws In Treating Injuries Of The Distal Aspect Of The Tibiofibular Syndesmosis, James A. Dollahite, Paul J. Goodwyn, Katherine J. Gavin, Richard A. Miller
UNM Orthopaedic Research Journal
Background: Several factors can affect the success of surgical treatment of injuries to the distal aspect of the tibiofibular syndesmosis, including the bony articulation between the distal aspect of the fibula, tibia, and the supporting ligamentous structures; number and size of screws; number of cortices penetrated; and planned routine removal of screws.
Methods: We conducted a retrospective review of radiographs and clinic notes for all patients who underwent open reduction and internal fixation of injury to the tibiofibular syndesmosis, which was performed by a single surgeon (RAM), between January 2011 and December 2014. Only screws were used. The screws were …
Lateral Versus Dorsal Plating For Treating Metacarpal And Phalanx Fractures: A Retrospective Cohort Study,
2017
University of New Mexico
Lateral Versus Dorsal Plating For Treating Metacarpal And Phalanx Fractures: A Retrospective Cohort Study, Joshua W. Hustedt, Collin C. Barber, Michael Bonnelli, Lloyd P. Champagne
UNM Orthopaedic Research Journal
Background: The purpose of this study was to investigate the differences between the dorsal and lateral plate position for metacarpal and phalanx fractures.
Methods: We conducted a retrospective review of prospectively collected patient data for 186 fractures treated by a single surgeon between 2009 and 2011. Rates of plate removal, total arc of postoperative motion (TAM), and patient and injury demographics were tested for association with plating position.
Results: Increasing age, larger plates, and dorsal plating were found in univariate analysis to be associated with decreased TAM and increased plate removal in phalanx but not in metacarpal fractures.
Conclusions: These …
Determining Frequency And Defining The Patient Profile Of Sacral Insufficiency Fractures,
2017
University of New Mexico
Determining Frequency And Defining The Patient Profile Of Sacral Insufficiency Fractures, Blake Obrock, Jeremy Wearn, Matthew L. Dehart, Paxton Gehling, Amer M. Mirza
UNM Orthopaedic Research Journal
Background: Insufficiency fractures at the sacrum represent a considerable cause of low back pain and disability within the geriatric population. However, there has never been a large-scale study examining the epidemiologic trends associated with the disease, and thus this condition has been largely under recognized.
Methods: This study analyzed a Nationwide Inpatient Sample (NIS) database to trend frequency and burden of sacral insufficiency fractures (SIF). All inpatient stays from 1998 to 2010 noted on the NIS were included if the case maintained at least one or more diagnostic code. A total of 257,697 unique admissions (63% women, 37% men) met …
Hierarchical Modeling Versus Regression Analysis For Evaluating Results Of Orthopaedic Studies That Use The National Inpatient Sample,
2017
University of New Mexico
Hierarchical Modeling Versus Regression Analysis For Evaluating Results Of Orthopaedic Studies That Use The National Inpatient Sample, Joshua W. Hustedt, Kade Mcquivey, John C. Hustedt
UNM Orthopaedic Research Journal
Background: Owing to its hierarchical sampling structure, the National Inpatient Sample (NIS) often involves clusters of study data. We aimed to (1) understand the statistical methods of currently published orthopaedic studies using NIS and (2) examine the role of hierarchical modeling versus traditional regression analysis in a retrospective cohort of patients from NIS.
Methods: We conducted a systematic review to examine statistical methods of orthopaedic studies (published between 2005 and 2014) using NIS. Ultimately, 132 studies were identified. We noted percentages of studies that used hierarchical modeling versus traditional regression analysis. Using NIS, we identified a retrospective cohort of patients …
Radiographic Prevalence Of Osteoarthritis Of The Scaphotrapeziotrapezoid Joint In Patients With Carpometacarpal Osteoarthritis Of The Thumb: A Retrospective Case Series,
2017
University of New Mexico
Radiographic Prevalence Of Osteoarthritis Of The Scaphotrapeziotrapezoid Joint In Patients With Carpometacarpal Osteoarthritis Of The Thumb: A Retrospective Case Series, Charlotte E. Orr, Robert Mercer, Deana M. Mercer, Drew K. Newhoff, Matthew D. Martin, Moheb S. Moneim
UNM Orthopaedic Research Journal
Background: In planning operative treatment of thumb carpometacarpal (CMC) joint osteoarthritis, surgeons should consider the presence of an arthritic scaphotrapeziotrapezoid (STT) joint. We aimed to determine the radiographic prevalence of concomitant (STT) osteoarthritis with thumb CMC osteoarthritis in patients who underwent surgical treatment at our institution. We hypothesized that the prevalence of concomitant arthritis at these 2 joints (STT and CMC) would be lower than previously reported.
Methods: Between September 2005 and July 2012, a total of 417 patients were identified from our institution using the Current Procedural Terminology code for thumb CMC joint arthroplasty (25447). After applying exclusion criteria …
External Fixation For Treating Tibial Shaft Fractures Using A Triangular Two-Planar Frame: A Computational And Biomechanical Study,
2017
University of New Mexico
External Fixation For Treating Tibial Shaft Fractures Using A Triangular Two-Planar Frame: A Computational And Biomechanical Study, Christina Salas, Daniel Hoopes, Mahmoud M. Reda Taha, Thomas A. Decoster
UNM Orthopaedic Research Journal
Background: Construct stability is a necessary characteristic of external fixators. Many commonly used fixators are constructed as symmetric one-plane frames. We postulate that asymmetric two-plane triangular constructs provide enhanced stability with simplicity and freedom in pin placement. We hypothesized that results of finite element analysis would determine optimal geometric configuration, and findings of mechanical testing would confirm the improved stability of two-plane triangular constructs.
Methods: Finite element modeling was used to analyze configurations for 16 triangular designs compared to a single-rod (SR) uniplanar frame. Variables included pin axial angulation (0°, 22.5°, 45°, and 90°), connectivity of the rod-to-pin couplers, and …
