Coronavirus Neurosurgical/Head And Neck Drape To Prevent Aerosolization Of Coronavirus Disease 2019 (Covid-19): The Lenox Hill Hospital/Northwell Health Solution,
2020
Northwell Health
Coronavirus Neurosurgical/Head And Neck Drape To Prevent Aerosolization Of Coronavirus Disease 2019 (Covid-19): The Lenox Hill Hospital/Northwell Health Solution, Rs D'Amico, D Khatri, K Kwan, G Baum, Y Serulle, D Silva, Ml Smith, Ja Ellis, M Levine, R Ortiz, Dj Langer, Ja Boockvar
Journal Articles
No abstract provided.
A Roadmap To Reopening A Neurosurgical Practice In The Age Of Covid-19,
2020
Northwell Health
A Roadmap To Reopening A Neurosurgical Practice In The Age Of Covid-19, Rs D'Amico, G Baum, Y Serulle, D Silva, Ml Smith, Ra Wallack, Ja Ellis, M Levine, R Oritz, Ja Boockvar, Dj Langer
Journal Articles
No abstract provided.
Computer-Assisted Planning For Minimally Invasive Anterior Two-Thirds Laser Corpus Callosotomy: A Feasibility Study With Probabilistic Tractography Validation: Automated Laser Callosotomy Trajectory Planning,
2020
Zucker School of Medicine at Hofstra/Northwell
Computer-Assisted Planning For Minimally Invasive Anterior Two-Thirds Laser Corpus Callosotomy: A Feasibility Study With Probabilistic Tractography Validation: Automated Laser Callosotomy Trajectory Planning, V. N. Vakharia, R. E. Sparks, S. B. Vos, Y. Bezchlibnyk, A. D. Mehta, J. T. Willie, C. Wu, A. Sharan, S. Ourselin, J. S. Duncan
Journal Articles
© 2020 The Authors Background: Anterior two-thirds corpus callosotomy is an effective palliative neurosurgical procedure for drug-refractory epilepsy that is most commonly used to treat drop-attacks. Laser interstitial thermal therapy is a novel stereotactic ablative technique that has been utilised as a minimally invasive alternative to resective and disconnective open neurosurgery. Case series have reported success in performing laser anterior two-thirds corpus callosotomy. Computer-assisted planning algorithms may help to automate and optimise multi-trajectory planning for this procedure. Objective: To undertake a simulation-based feasibility study of computer-assisted corpus callostomy planning in comparison with expert manual plans in the same patients. Methods: …
Carotid Revascularization And Its Effect On Cognitive Function: A Prospective Nonrandomized Multicenter Clinical Study,
2020
Zucker School of Medicine at Hofstra/Northwell
Carotid Revascularization And Its Effect On Cognitive Function: A Prospective Nonrandomized Multicenter Clinical Study, J. L. Whooley, B. C. David, H. H. Woo, B. L. Hoh, K. B. Raftery, A. Hussain Siddiqui, M. Westerveld, S. Amin-Hanjani, Z. Ghogawala
Journal Articles
© 2020 The Author(s) Background: There is conflicting data on the effect of carotid revascularization on cognitive function. Objective: To examine cerebral blood flow and cognitive function after carotid revascularization. Methods: Patients with unilateral, asymptomatic hemodynamically significant carotid artery stenosis (80% by computed tomography angiography or magnetic resonance angiography) were eligible. Cerebral blood flow was measured preoperatively and 1 month postoperatively using quantitative phase contrast magnetic resonance angiography. Preoperative flow impairment was defined as ipsilateral flow at least 20% less than contralateral flow (ie, an ipsilateral and/or contralateral flow ratio ≤0.8). Significant improvement in blood flow was defined as at …
The Α7 Nicotinic Acetylcholine Receptor Agonist, Gts-21, Attenuates Hyperoxia-Induced Acute Inflammatory Lung Injury By Alleviating The Accumulation Of Hmgb1 In The Airways And The Circulation,
2020
Zucker School of Medicine at Hofstra/Northwell
The Α7 Nicotinic Acetylcholine Receptor Agonist, Gts-21, Attenuates Hyperoxia-Induced Acute Inflammatory Lung Injury By Alleviating The Accumulation Of Hmgb1 In The Airways And The Circulation, R. A. Sitapara, A. G. Gauthier, S. I. Valdés-Ferrer, M. Lin, V. Patel, M. Wang, A. T. Martino, K. J. Tracey, V. A. Pavlov, L. L. Mantell, +2 Additional Authors
Journal Articles
© 2020 The Author(s). Background: Oxygen therapy, using supraphysiological concentrations of oxygen (hyperoxia), is routinely administered to patients who require respiratory support including mechanical ventilation (MV). However, prolonged exposure to hyperoxia results in acute lung injury (ALI) and accumulation of high mobility group box 1 (HMGB1) in the airways. We previously showed that airway HMGB1 mediates hyperoxia-induced lung injury in a mouse model of ALI. Cholinergic signaling through the α7 nicotinic acetylcholine receptor (α7nAChR) attenuates several inflammatory conditions. The aim of this study was to determine whether 3-(2,4 dimethoxy-benzylidene)-anabaseine dihydrochloride, GTS-21, an α7nAChR partial agonist, inhibits hyperoxia-induced HMGB1 accumulation in …
Guidelines For The Management Of Severe Traumatic Brain Injury: 2020 Update Of The Decompressive Craniectomy Recommendations,
2020
Zucker School of Medicine at Hofstra/Northwell
Guidelines For The Management Of Severe Traumatic Brain Injury: 2020 Update Of The Decompressive Craniectomy Recommendations, G. W. Hawryluk, A. M. Rubiano, A. M. Totten, C. O'Reilly, J. S. Ullman, S. L. Bratton, R. Chesnut, O. A. Harris, N. Kissoon, J. Ghajar, +6 Additional Authors
Journal Articles
© Congress of Neurological Surgeons 2020. When the fourth edition of the Brain Trauma Foundation's Guidelines for the Management of Severe Traumatic Brain Injury were finalized in late 2016, it was known that the results of the RESCUEicp (Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension) randomized controlled trial of decompressive craniectomy would be public after the guidelines were released. The guideline authors decided to proceed with publication but to update the decompressive craniectomy recommendations later in the spirit of "living guidelines," whereby topics are updated more frequently, and between new editions, when important new evidence is published. The update …
Brain-Informed Speech Separation (Biss) For Enhancement Of Target Speaker In Multitalker Speech Perception,
2020
Zucker School of Medicine at Hofstra/Northwell
Brain-Informed Speech Separation (Biss) For Enhancement Of Target Speaker In Multitalker Speech Perception, E. Ceolini, J. Hjortkjær, D. D. Wong, J. O'Sullivan, V. S. Raghavan, J. Herrero, A. D. Mehta, S. C. Liu, N. Mesgarani
Journal Articles
© 2020 Hearing-impaired people often struggle to follow the speech stream of an individual talker in noisy environments. Recent studies show that the brain tracks attended speech and that the attended talker can be decoded from neural data on a single-trial level. This raises the possibility of “neuro-steered” hearing devices in which the brain-decoded intention of a hearing-impaired listener is used to enhance the voice of the attended speaker from a speech separation front-end. So far, methods that use this paradigm have focused on optimizing the brain decoding and the acoustic speech separation independently. In this work, we propose a …
Estimating And Interpreting Nonlinear Receptive Field Of Sensory Neural Responses With Deep Neural Network Models,
2020
Zucker School of Medicine at Hofstra/Northwell
Estimating And Interpreting Nonlinear Receptive Field Of Sensory Neural Responses With Deep Neural Network Models, M. Keshishian, H. Akbari, B. Khalighinejad, J. L. Herrero, A. D. Mehta, N. Mesgarani
Journal Articles
No abstract provided.
Does Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results Of Embolization Of Intracranial Aneurysms At 1 Year: A Randomized Trial,
2020
Zucker School of Medicine at Hofstra/Northwell
Does Increasing Packing Density Using Larger Caliber Coils Improve Angiographic Results Of Embolization Of Intracranial Aneurysms At 1 Year: A Randomized Trial, J. Raymond, J. Ghostine, B. A. Van Adel, J. J. Shankar, D. Iancu, A. P. Mitha, P. Kvamme, R. D. Turner, H. H. Woo, T. E. Darsaut, +13 Additional Authors
Journal Articles
© 2020 American Society of Neuroradiology. All rights reserved. BACKGROUND AND PURPOSE: The impact of increased aneurysm packing density on angiographic outcomes has not been studied in a randomized trial. We sought to determine the potential for larger caliber coils to achieve higher packing densities and to improve the angiographic results of embolization of intracranial aneurysms at 1 year. MATERIALS AND METHODS: Does Embolization with Larger Coils Lead to Better Treatment of Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled clinical trial. Patients had 4- to 12-mm unruptured aneurysms. Treatment allocation to either 15- (experimental) or 10-caliber coils …
Coronavirus Neurosurgical/Head And Neck Drape To Prevent Aerosolization Of Coronavirus Disease 2019 (Covid-19): The Lenox Hill Hospital/Northwell Health Solution,
2020
Northwell Health
Coronavirus Neurosurgical/Head And Neck Drape To Prevent Aerosolization Of Coronavirus Disease 2019 (Covid-19): The Lenox Hill Hospital/Northwell Health Solution, R. S. D'Amico, D. Khatri, K. Kwan, G. Baum, Y. Serulle, D. Silva, M. L. Smith, J. A. Ellis, M. Levine, R. Ortiz, D. J. Langer, J. A. Boockvar
Journal Articles
No abstract provided.
Behavioral Changes Without Respiratory Symptoms As A Presenting Sign Of Covid-19 Encephalitis.,
2020
Zucker School of Medicine at Hofstra/Northwell
Behavioral Changes Without Respiratory Symptoms As A Presenting Sign Of Covid-19 Encephalitis., T. Rebeiz, K. Lim-Hing, S. Khazanehdari, K. Rebeiz
Journal Articles
The clinical presentation, diagnosis, and treatment of coronavirus disease 2019 (COVID-19) encephalitis are still being characterized. Few case reports describing COVID-19 encephalitis are available in the literature. We present a case of COVID-19 encephalitis who presented with behavioral disturbances without respiratory symptoms.
Covid-19 And Neurosurgical Practice: An Interim Report,
2020
Zucker School of Medicine at Hofstra/Northwell
Covid-19 And Neurosurgical Practice: An Interim Report, S Amin-Hanjani, Nc Bambakidis, Fg Barker, Bs Carter, Km Cockroft, R Du, Jf Fraser, Mg Hamilton, M Schulder, G Zada, +9 Additional Authors
Journal Articles
No abstract provided.
Minimizing Sars-Cov-2 Exposure When Performing Surgical Interventions During The Covid-19 Pandemic,
2020
Zucker School of Medicine at Hofstra/Northwell
Minimizing Sars-Cov-2 Exposure When Performing Surgical Interventions During The Covid-19 Pandemic, As Pandey, Aj Ringer, At Rai, P Kan, P Jabbour, Ah Siddiqui, E Levy, K Snyder, H Riina, D Langer, +9 Additional Authors
Journal Articles
No abstract provided.
Cerebellar Infarction Requiring Surgical Decompression In Patient With Covid 19 Pathological Analysis And Brief Review,
2020
Zucker School of Medicine at Hofstra/Northwell
Cerebellar Infarction Requiring Surgical Decompression In Patient With Covid 19 Pathological Analysis And Brief Review, H. N. Patel, A. Syed, J. S. Lobel, R. Galler, J. Georges, M. Carmody, M. Puumala
Journal Articles
© 2020 The Authors Background: This report and literature review describes a case of a COVID-19 patient who suffered a cerebellar stroke requiring neurosurgical decompression. This is the first reported case of a sub-occipital craniectomy with brain biopsy in a COVID-19 patient showing leptomeningeal venous intimal inflammation. Clinical description: The patient is a 48-year-old SARS-COV-2 positive male with multiple comorbidities, who presented with fevers and respiratory symptoms, and imaging consistent with multifocal pneumonia. On day 5 of admission, the patient had sudden change in mental status, increased C-Reactive Protein, ferritin and elevated Interleukin-6 levels. Head CT showed cerebral infarction from …
Extracellular Hmgb1: A Therapeutic Target In Severe Pulmonary Inflammation Including Covid-19?,
2020
Zucker School of Medicine at Hofstra/Northwell
Extracellular Hmgb1: A Therapeutic Target In Severe Pulmonary Inflammation Including Covid-19?, U Andersson, W Ottestad, Kj Tracey
Journal Articles
No abstract provided.
Letter: Considerations For Performing Emergent Neurointerventional Procedures In A Covid-19 Environment.,
2020
Zucker School of Medicine at Hofstra/Northwell
Letter: Considerations For Performing Emergent Neurointerventional Procedures In A Covid-19 Environment., As Pandey, Aj Ringer, A Rai, Pt Kan, Pm Jabbour, A Siddiqui, E Levy, Kv Snyder, Ha Riina, D Langer, +9 Additional Authors
Journal Articles
No abstract provided.
Comparison Of A Continuous Noninvasive Temperature To Monitor Core Temperature Measures During Targeted Temperature Management,
2020
Zucker School of Medicine at Hofstra/Northwell
Comparison Of A Continuous Noninvasive Temperature To Monitor Core Temperature Measures During Targeted Temperature Management, M. Wagner, K. Lim-Hing, M. A. Bautista, B. Blaber, T. Ryder, J. Haymore, N. Badjatia
Journal Articles
No abstract provided.
Author Correction: Noninvasive Sub-Organ Ultrasound Stimulation For Targeted Neuromodulation (Nature Communications, (2019), 10, 1, (952), 10.1038/S41467-019-08750-9),
2020
Northwell Health
Author Correction: Noninvasive Sub-Organ Ultrasound Stimulation For Targeted Neuromodulation (Nature Communications, (2019), 10, 1, (952), 10.1038/S41467-019-08750-9), V. Cotero, Y. Fan, T. Tsaava, A. M. Kressel, I. Hancu, T. R. Coleman, S. Zanos, K. J. Tracey, S. S. Chavan, C. Puleo, +10 Additional Authors
Journal Articles
© 2020, The Author(s). This article contained an error in the ordinate axis in Fig. 2d, where the units were reported as nmol/L. The unit should have been reported as pg/ml. This has now been corrected in both the PDF and HTML versions of the Article.
Application Of Multimodal Neuromonitoring In Posterior Inferior Cerebellar Artery Aneurysm Clippings: Review Of Two Cases.,
2020
Northwell Health
Application Of Multimodal Neuromonitoring In Posterior Inferior Cerebellar Artery Aneurysm Clippings: Review Of Two Cases., J. W. Silverstein, A. Rosenthal, K. Kwan, K. Wagner, J. A. Ellis
Journal Articles
Neurophysiological monitoring is advocated for the prevention of neurological sequelae secondary to the clipping of an aneurysm involved in posterior circulation. Unfortunately, there is a paucity in the literature regarding what neurophysiological monitoring techniques are best employed. The authors here present two cases where multimodal neuromonitoring techniques were used during the clippings of two posterior inferior cerebellar artery (PICA) aneurysms. There is increased neurologic morbidity associated with PICA aneurysm clippings, as a number of eloquent structures live in close proximity to the PICA. The application of a multimodal neuromonitoring paradigm may reduce a poor neurological outcome.
N-Butyl Cyanoacrylate Transvenous Arteriovenous Malformation Embolization With Arterial Balloon Assistance: Defining Parameters For A Transvenous Approach As A Potential Upfront Treatment Option In Managing Cerebral Arteriovenous Malformations., C. Higbie, D. Khatri, B. Ligas, R. Ortiz, D. Langer
Journal Articles
Complete obliteration of arteriovenous malformations (AVMs) using a transvenous approach as the primary and stand-alone treatment modality has been increasingly considered as a useful endovascular approach in the treatment of AVMs. AVMs are typically treated with microsurgery, stereotactic radiosurgery, endovascular embolization, or some combination of the three methods. Preservation of the draining vein is a key requisite common to all treatment modalities. Transvenous embolization (TVE) is conventionally not recommended as a stand-alone treatment for the vast majority of AVMs and has been thought to be best indicated when traditional approaches are considered less safe and when specific evaluation criteria are …
