Anomalous Right Coronary Artery Arising From The Pulmonary Artery, 2013 Lehigh Valley Health Network
Anomalous Right Coronary Artery Arising From The Pulmonary Artery, Ashish Kabra, James Wu, Matthew Martinez
James K Wu MD
No abstract provided.
Fabry's Disease With Lvot Obstruction: Diagnosis And Management, 2013 University of South Florida Morsani College of Medicine
Fabry's Disease With Lvot Obstruction: Diagnosis And Management, Jacob Blount, James Wu, Matthew Martinez
James K Wu MD
A 46-year-old male was diagnosed with hypertrophic cardiomyopathy (HCM) and severe left ventricular outflow tract (LVOT) obstruction. Genetic testing revealed that this was a "mimic of HCM" and the true diagnosis was Fabry's disease, although there were no other clinical features of Fabry's. Despite maximal medical therapy he remained symptomatic from the outflow tract gradient and required surgical myectomy for symptom relief. This case illustrates the diagnosis of an HCM mimic by genetic testing.
Risk Factors Affecting Surgical Outcomes In Patients Undergoing Hypothermic Circulatory Arrest During Aortic Surgeries: A 10-Year Study, 2013 Lehigh Valley Health Network
Risk Factors Affecting Surgical Outcomes In Patients Undergoing Hypothermic Circulatory Arrest During Aortic Surgeries: A 10-Year Study, Bree Ann Young, James K. Wu, Martin E. Matsumura Md, Sanjay M. Mehta Md, Theodore G. Phillips Md, Michael F. Szwerc Md, Gary W. Szydlowski Md, Raymond L. Singer Md
James K. Wu, M.D.
No abstract provided.
Treatment Of Acute Aortic Dissection At A Community Hospital: A 10 Year Review Of Outcomes., 2013 Lehigh Valley Health Network
Treatment Of Acute Aortic Dissection At A Community Hospital: A 10 Year Review Of Outcomes., Timothy Misselbeck Md, Stephen Deturk, Matthew Wilson, Theodore Phillips Md, Michael Szwerc Md, Sanjay Mehta Md, Gary Szydlowski Md, Raymond Singer Md, James Wu Md
James K Wu MD
No abstract provided.
Outcome Of Traumatic Aortic Rupture: A 14-Year Experience, 2013 Lehigh Valley Health Network
Outcome Of Traumatic Aortic Rupture: A 14-Year Experience, Matthew Wilson, James K. Wu, Sanjay M. Mehta Md, Theodore G. Phillips Md, Raymond L. Singer Md, Michael F. Szwerc Md, Gary W. Szydlowski Md
James K. Wu, M.D.
No abstract provided.
Risk Factors Affecting Outcomes In Patients Undergoing Hypothermic Circulatory Arrest During Aortic Surgeries, 2013 Lehigh Valley Health Network
Risk Factors Affecting Outcomes In Patients Undergoing Hypothermic Circulatory Arrest During Aortic Surgeries, Bree Ann Young, James K. Wu Md, Martin E. Matsumura Md, Tim S. Misselbeck Md, Sanjay M. Mehta Md, Theodore G. Phillips Md, Michael F. Szwerc Md, Gary W. Szydlowski Md, Raymond L. Singer Md
James K. Wu, M.D.
No abstract provided.
Conventional Isolated Aortic Valve Replacement In Octogenarians: A 10-Year Single Center Experience, 2013 Lehigh Valley Health Network
Conventional Isolated Aortic Valve Replacement In Octogenarians: A 10-Year Single Center Experience, James K. Wu Md, Justin D. Roberts Do, Gregory S. Troutman Bs, Michael J. Weiss Mph, Sanjay M. Mehta Md, Theodore G. Phillips Md, Michael F. Szwerc Md, Gary W. Szydlowski Md, Tim S. Misselbeck Md, Raymond L. Singer Md
James K Wu MD
No abstract provided.
Successful Long-Term Extracorporeal Cardiopulmonary Membrane Oxygenation Without Anti-Coagulation, 2013 Lehigh Valley Health Network
Successful Long-Term Extracorporeal Cardiopulmonary Membrane Oxygenation Without Anti-Coagulation, Janissa Nair, Dorothea T. Watson Do, Rita Pechulis Md, Fccp, Nicholas M. Rini Pa-C, Tim S. Misselbeck Md, Kenneth Miller Rrt, James K. Wu Md
James K. Wu, M.D.
No abstract provided.
Durability, Reliability, Viability: 48 Year-Survival Of A Starr-Edwards Mitral Valve, 2013 Lehigh Valley Health Network
Durability, Reliability, Viability: 48 Year-Survival Of A Starr-Edwards Mitral Valve, Bilal Ayub, Justin Guthier, James Wu
James K Wu MD
No abstract provided.
Causes Of Death In Surgically Treated Patients With Type A Aortic Dissection - A Ten Year Review, 2013 Lehigh Valley Health Network
Causes Of Death In Surgically Treated Patients With Type A Aortic Dissection - A Ten Year Review, James K. Wu Md, Eilizabeth Depaolo Bs, Theodore G. Phillips Md, Tim S. Misselbeck Md
James K. Wu, M.D.
No abstract provided.
Venous Thromboembolism In Patients With Heart Failure: In-Hospital And Chronic Use Of Anti-Coagulants For Prevention, 2013 Lehigh Valley Health Network
Venous Thromboembolism In Patients With Heart Failure: In-Hospital And Chronic Use Of Anti-Coagulants For Prevention, Nasir Shariff, Abdul Aleem, Vadim Levin, Sudip Nanda, Matthew Martinez, Stacey Smith, Ronald Freudenberger
Vadim A Levin MD
No abstract provided.
Ranolazine—Treatment Of Ventricular Tachycardia And Symptomatic Ventricular Premature Beats In Ischemic Cardiomyopathy, 2013 Lehigh Valley Health Network
Ranolazine—Treatment Of Ventricular Tachycardia And Symptomatic Ventricular Premature Beats In Ischemic Cardiomyopathy, Sudip Nanda, Vadim Levin, Matthew Martinez, Ronald Freudenberger
Vadim A Levin MD
No abstract provided.
Pre-Operative Angiotensin Converting Enzyme Inhibitors And Angiotensin Receptor Blockers On The Occurrence Of Post Operative Atrial Fibrillation After Cardiac Valve Department Of Surgery, 2013 Lehigh Valley Health Network
Pre-Operative Angiotensin Converting Enzyme Inhibitors And Angiotensin Receptor Blockers On The Occurrence Of Post Operative Atrial Fibrillation After Cardiac Valve Department Of Surgery, Nasir Shariff, Matthew W. Martinez Md, Ravi V. Desai Md, Michael J. Weiss, Vadim Levin Md, Larry E. Jacobs Md, Martin E. Matsumura Md, Ronald S. Freudenberger Md
Vadim A Levin MD
No abstract provided.
Atrial Fibrillation In Patients With Heart Failure: Role Of Catheter Ablation Therapies, 2013 Lehigh Valley Health Network
Atrial Fibrillation In Patients With Heart Failure: Role Of Catheter Ablation Therapies, Nasir Shariff, Abdul Aleem, Vadim Levin, Mukesh Singh, Nauman Islam, Ronald Freudenberger
Vadim A Levin MD
No abstract provided.
Interatrial Conduction Correlates With Optimal Atrioventricular Timing In Cardiac Resynchronization Therapy Devices, 2013 Lehigh Valley Health Network
Interatrial Conduction Correlates With Optimal Atrioventricular Timing In Cardiac Resynchronization Therapy Devices, Vadim Levin, Mehdi Razavi, Robert Coll, James Coles, Aleksandre Sambelashvili
Vadim A Levin MD
No abstract provided.
Dabigatran: A New Chapter In Anticoagulation, 2013 Lehigh Valley Health Network
Dabigatran: A New Chapter In Anticoagulation, Shawn Ahmed, Vadim Levin, Robert Malacoff, Matthew Martinez
Vadim A Levin MD
No abstract provided.
Novel Oral Anticoagulants For Stroke Prevention In Patients With Atrial Fibrillation: Dawn Of A New Era, 2013 Lehigh Valley Health Network
Novel Oral Anticoagulants For Stroke Prevention In Patients With Atrial Fibrillation: Dawn Of A New Era, Tahmeed Contractor, Vadim Levin, Matthew Martinez, Francis Marchinski
Vadim A Levin MD
No abstract provided.
Combination Of Necroptosis And Apoptosis Inhibition Enhances Cardioprotection Against Myocardial Ischemia-Reperfusion Injury., 2013 Osaka Dental University, Osaka, Japan
Combination Of Necroptosis And Apoptosis Inhibition Enhances Cardioprotection Against Myocardial Ischemia-Reperfusion Injury., Shizuka Koshinuma, Masami Miyamae, Kazuhiro Kaneda, Junichiro Kotani, Vincent M. Figueredo
Division of Cardiology Faculty Papers
PURPOSE: Necroptosis has been proposed as a mode of cell death that is a caspase-independent programmed necrosis. We investigated whether necroptosis is involved in myocardial ischemia-reperfusion injury in isolated guinea pig hearts and, if so, whether simultaneous inhibition of necroptosis and apoptosis confers enhanced cardioprotection.
METHODS: Isolated perfused guinea pig hearts were subjected to 30 min ischemia and 4 h reperfusion (control = CTL, n = 8). Necrostatin-1 (necroptosis inhibitor, 10 μM), Z-VAD (apoptosis inhibitor, 0.1 μM) and both inhibitors were administered starting 5 min before ischemia and during the initial 30 min of reperfusion (Nec, Z-VAD, Nec + Z-VAD; …
Meditation: Should A Cardiologist Care?, 2013 Einstein Institute for Heart and Vascular Health, Einstein Medical Center
Meditation: Should A Cardiologist Care?, Stephen Olex, Andrew B. Newberg, Md, Vincent M. Figueredo, M.D.
Division of Cardiology Faculty Papers
Meditation refers to a family of practices that may share many similarities, but can have differences in underlying methods and goals. Religious and spiritual associations are common but are not requisite for meditation practice and it should be recognized that the basis of many if not all practices is the training of the brain and body, a process that appears to have profound effects on both structure and function. In recent decades there has been interest regarding the effects of these ancient practices on the cardiovascular system, as meditation has intuitive appeal for benefit in this area. Though there is …
Sevoflurane Confers Additive Cardioprotection To Ethanol Preconditioning Associated With Enhanced Phosphorylation Of Glycogen Synthase Kinase-3Β And Inhibition Of Mitochondrial Permeability Transition Pore Opening., 2013 Osaka Dental University
Sevoflurane Confers Additive Cardioprotection To Ethanol Preconditioning Associated With Enhanced Phosphorylation Of Glycogen Synthase Kinase-3Β And Inhibition Of Mitochondrial Permeability Transition Pore Opening., Anna Onishi, Masami Miyamae, Hiroshi Inoue, Kazuhiro Kaneda, Chika Okusa, Yoshitaka Inamura, Mayumi Shiomi, Shizuka Koshinuma, Yoshihiro Momota, Vincent M. Figueredo
Division of Cardiology Faculty Papers
OBJECTIVE: The purposes of this study were to investigate whether sevoflurane (SEVO) enhances moderate-dose ethanol (EtOH) preconditioning and whether this additional cardioprotection is associated with glycogen synthase kinase-3β (GSK-3β), protein kinase B (Akt), mammalian target of rapamycin (mTOR), 70-kDa ribosomal s6 kinase-1 (p70s6K), and/or mitochondrial permeability transition pore (MPTP) opening.
DESIGN: In vitro study using an isolated heart Langendorff preparation.
SETTING: University research laboratory.
PARTICIPANTS: Male guinea pigs (n = 170).
INTERVENTIONS: Isolated perfused guinea pig hearts underwent 30-minute ischemia and 120-minute reperfusion (control). The EtOH group received 5% EtOH in the drinking water for 8 weeks. Anesthetic preconditioning was …