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1,059 full-text articles. Page 31 of 47.

Response To A Case Report Titled: Anaesthetic Management Of A Patient With Left Ventricular Non-Compaction Undergoing Laparotomy, Faraz Shafiq, M Irfan Ul Haq, Anwar ul Huda 2019 Aga Khan University

Response To A Case Report Titled: Anaesthetic Management Of A Patient With Left Ventricular Non-Compaction Undergoing Laparotomy, Faraz Shafiq, M Irfan Ul Haq, Anwar Ul Huda

Department of Anaesthesia

No abstract provided.


National Approach To Standardize And Improve Mechanical Ventilation, Yaseen M. Arabi, Zohair Al Aseri, Tareef Alaama, Abdulrahman Alqahtani, Abdulrhman Alharthy, Abdullah Almotairi, Eman Al Qasim, Abdullah A. Alzahrani, Mohammed Al Qarni, Asad Latif 2019 King Abdullah International Medical Research Center, Saudi Arabia

National Approach To Standardize And Improve Mechanical Ventilation, Yaseen M. Arabi, Zohair Al Aseri, Tareef Alaama, Abdulrahman Alqahtani, Abdulrhman Alharthy, Abdullah Almotairi, Eman Al Qasim, Abdullah A. Alzahrani, Mohammed Al Qarni, Asad Latif

Department of Anaesthesia

NASAM (National Approach to Standardize and Improve Mechanical Ventilation) is a national collaborative quality improvement project in Saudi Arabia. It aims to improve the care of mechanically ventilated patients by implementing evidence-based practices with the goal of reducing the rate of ventilator-associated events and therefore reducing mortality, mechanical ventilation duration and intensive care unit (ICU) length of stay. The project plans to extend the implementation to a total of 100 ICUs in collaboration with multiple health systems across the country. As of March 22, 2019, a total of 78 ICUs have registered from 6 different health sectors, 48 hospitals, and …


The Oculocardiac Reflex And Depth Of Anesthesia Measured By Brain Wave., Robert W Arnold, Aleah N Bond, Melissa McCall, Leif Lunoe 2019 Providence Anesthesia Group, Anchorage, Alaska, USA

The Oculocardiac Reflex And Depth Of Anesthesia Measured By Brain Wave., Robert W Arnold, Aleah N Bond, Melissa Mccall, Leif Lunoe

Articles, Abstracts, and Reports

BACKGROUND: The oculocardiac reflex (OCR), bradycardia that occurs during strabismus surgery is a type of trigemino-cardiac reflex (TCR) is blocked by anticholinergics and enhanced by opioids and dexmedetomidine. Two recent studies suggest that deeper inhalational anesthesia monitored by BIS protects against OCR; we wondered if our data correlated similarly.

METHODS: In an ongoing, prospective study of OCR/TCR elicited by 10-s, 200 g square-wave traction on extraocular muscles (EOM) from 2009 to 2013, anesthetic depth was estimated in cohorts using either BIS or Narcotrend monitors. The depth of anesthesia was deliberately varied between first and second EOM tested.

RESULTS: From 1992 …


Sleeping Pattern Before Thoracic Surgery: A Comparison Of Baseline And Night Before Surgery, Mohammad Hamid, Mohammad Irfan Akhtar, Saba Ahmed 2019 Aga Khan University Karachi

Sleeping Pattern Before Thoracic Surgery: A Comparison Of Baseline And Night Before Surgery, Mohammad Hamid, Mohammad Irfan Akhtar, Saba Ahmed

Department of Anaesthesia

Background: Sleep deprivation is considered a stress factor in the perioperative period. There are several studies on sleep disturbance after surgery but very limited literature available on preoperative sleep patterns, predictors of sleep disturbance and its effect on surgical outcome.
Methodology: Patients scheduled for thoracic surgery were asked to fill out a written Pittsburgh Sleep Quality Index (PSQI) questionnaire. The primary investigator explained this form to all the patients. This was filled out before premedication for subjective assessment of sleeping pattern at two different time point. Only those patients included who spent the previous night at home. Participants were asked …


Intravenous Meloxicam For The Treatment Of Moderate To Severe Acute Pain: A Pooled Analysis Of Safety And Opioid-Reducing Effects., Eugene R. Viscusi, Tong J. Gan, Sergio Bergese, Neil Singla, Randall J. Mack, Stewart W. McCallum, Wei Du, Sue Hobson 2019 Thomas Jefferson University

Intravenous Meloxicam For The Treatment Of Moderate To Severe Acute Pain: A Pooled Analysis Of Safety And Opioid-Reducing Effects., Eugene R. Viscusi, Tong J. Gan, Sergio Bergese, Neil Singla, Randall J. Mack, Stewart W. Mccallum, Wei Du, Sue Hobson

Department of Anesthesiology Faculty Papers

BACKGROUND AND OBJECTIVES: To describe the safety and tolerability of intravenous meloxicam compared with placebo across all phase II/III clinical trials.

METHODS: Safety data and opioid use from subjects with moderate to severe postoperative pain who received ≥1 dose of intravenous meloxicam (5-60 mg) or placebo in 1 of 7 studies (4 phase II; 3 phase III) were pooled. Data from intravenous meloxicam 5 mg, 7.5 mg and 15 mg groups were combined (low-dose subset).

RESULTS: A total of 1426 adults (86.6% white; mean age: 45.8 years) received ≥1 dose of meloxicam IV; 517 (77.6% white; mean age: 46.7 years) …


The Utility Of Neutrophil Gelatinase-Associated Lipocalin (Ngal) As A Marker Of Acute Kidney Injury (Aki) In Critically Ill Patients, Shabnum Khawaja, Lena Jafri, Imran Siddiqui, Madiha Hashmi, Farooq Ghani 2019 Aga Khan University

The Utility Of Neutrophil Gelatinase-Associated Lipocalin (Ngal) As A Marker Of Acute Kidney Injury (Aki) In Critically Ill Patients, Shabnum Khawaja, Lena Jafri, Imran Siddiqui, Madiha Hashmi, Farooq Ghani

Department of Pathology and Laboratory Medicine

In current clinical practice, Serum Creatinine (SCr) is a commonly used marker for the diagnosis of acute kidney injury (AKI). Unfortunately, due to a delayed increase in SCr, it is unable to accurately estimate the timing of the injury. The purpose of this study was to assess the ability of plasma neutrophil gelatinase-associated lipocalin (pNGAL) to predict AKI in critically ill adult patients. The study was conducted at the Section of Chemical Pathology, Department of Pathology& Laboratory Medicine in collaboration with Department of Anesthesiology, at Aga Khan University Hospital in Karachi, Pakistan. Subjects in the age groups of18 to …


The Accuracy Of Blood Pressure Measurement By A Smartwatch And A Portable Health Device, Vignesh Murali, Noud van Helmond, Cecilia G. Freeman, Christina Hahnen, Nilanjan Haldar, Jacquelyn N. Hamati, Dylan M. Bard, Geno J. Merli, Jeffrey I. Joseph 2019 Thomas Jefferson University

The Accuracy Of Blood Pressure Measurement By A Smartwatch And A Portable Health Device, Vignesh Murali, Noud Van Helmond, Cecilia G. Freeman, Christina Hahnen, Nilanjan Haldar, Jacquelyn N. Hamati, Dylan M. Bard, Geno J. Merli, Jeffrey I. Joseph

Phase 1

Introduction: Hypertension is a leading cause of mortality. Proper blood pressure (BP) control can be achieved by lifestyle modification, pharmacotherapy, and frequent measurements. With the growing popularity of cuffless blood pressure monitors, it is important to independently validate their accuracy.

Objective: We evaluated two cuffless blood pressure monitors, The Everlast TR10 fitness watch and the BodiMetrics Performance Monitor, for their accuracy and precision in BP measurements.

Methods: Using a protocol derived from the ANSI/AAMI/ISO 2013 standard for evaluating automated sphygmomanometers, we measured the blood pressures of 85 patients recruited from the Thomas Jefferson University Hospital Preadmission Testing Center with two …


Outcomes Reporting In Regional Anesthesia Patients: A Comparison Of Manual Phone Calls Versus Automated Phone App Messaging, Gavyn Ooi, MBA, Eric Schwenk, MD, FASA, Jeffrey Mojica, DO, Alexander Grant, MD, Max Shilling, MD, David Barnabei, MD, Jennifer Lessin, BA, RN, CCRC, Marc Torjman, PhD, Kent Berg, MD, MBA 2019 Thomas Jefferson University

Outcomes Reporting In Regional Anesthesia Patients: A Comparison Of Manual Phone Calls Versus Automated Phone App Messaging, Gavyn Ooi, Mba, Eric Schwenk, Md, Fasa, Jeffrey Mojica, Do, Alexander Grant, Md, Max Shilling, Md, David Barnabei, Md, Jennifer Lessin, Ba, Rn, Ccrc, Marc Torjman, Phd, Kent Berg, Md, Mba

Phase 1

Automation of patient follow-up via mobile phone apps have the potential to save time for physicians, standardize responses from patients, and increase the patient response rate. Studies that assess the effectiveness of mobile phone-based surveys have been favorable, with completion rates of about 60% in the surgical population. The impact of mobile phone-based patient management in anesthesia deserves further study. This study examines the follow-up success rates of (1) manual phone calls (the current standard of care) vs. (2) automated patient outreach (APO) in patients who receive a regional anesthesia block procedure.

As part of normal follow up, anesthesia team …


Correlation Of Trainees' Selection Scores With Their Subsequent Performance During Specialty Training In Anesthesiology, Aliya Ahmed, Rashida Ahmed 2019 Aga Khan University

Correlation Of Trainees' Selection Scores With Their Subsequent Performance During Specialty Training In Anesthesiology, Aliya Ahmed, Rashida Ahmed

Department of Anaesthesia

Objective: To determine the correlation of trainee selection scores (TSS) with subsequent performance in anesthesiology trainees at a university hospital.
Study Design: Descriptive analytical study.
Place and Duration of Study: The Aga Khan University Hospital, Karachi, from August 2016 to January 2017.
Methodology: Data were collected on 44 anesthesiology trainees completing their training between 2009 and 2015. TSS consisted of entrance test, final-year medical school scores, and interviews. Assessment included written tests, viva voce, and clinical assessment. Non-parametric Spearman rank correlation coefficient was computed to assess the relationship between scores.
Results: Weak correlation was found between TSS and overall assessment …


Applying Quality Improvement Methods To Neglected Conditions: Development Of The South Asia Burn Registry (Sabr), Nukhba Zia Nukhba Zia, Asad Latif, Saidur Rahman Mashreky, Ehmer Al-Ibran, Madiha Hashmi, A. K. M. Fazlur Rahman, Sazzad Khondoker, Mohammed Saeed Quraishy, Adnan A. Hyder 2019 Johns Hopkins Bloomberg School of Public Health, Baltimore, USA

Applying Quality Improvement Methods To Neglected Conditions: Development Of The South Asia Burn Registry (Sabr), Nukhba Zia Nukhba Zia, Asad Latif, Saidur Rahman Mashreky, Ehmer Al-Ibran, Madiha Hashmi, A. K. M. Fazlur Rahman, Sazzad Khondoker, Mohammed Saeed Quraishy, Adnan A. Hyder

Department of Anaesthesia

Objective: South Asia has the highest mortality rate from burns in the world. Application of quality improvement methods to burn care can help identify health system gaps. Our overall aim is to introduce a sustainable hospital-based burn registry for resource-constrained settings to assess health outcomes of burn injury patients presenting to dedicated burn injury centers in South Asia.
Results: The South Asia Burn Registry (SABR) is implemented through collaborative approach in selected burn centers in Bangladesh and Pakistan. Th registry collects data on burn injury events, the care provided, and the functional status of patients at discharge from burn centers. …


A Randomized, Double-Blinded Trial Comparing The Effectiveness Of Tranexamic Acid And Epsilon-Aminocaproic Acid In Reducing Bleeding And Transfusion In Cardiac Surgery, J. Leff, A. Rhee, S. Nair, D. Lazar, S. Sathyanarayana, L. Shore-Lesserson 2019 Zucker School of Medicine at Hofstra/Northwell

A Randomized, Double-Blinded Trial Comparing The Effectiveness Of Tranexamic Acid And Epsilon-Aminocaproic Acid In Reducing Bleeding And Transfusion In Cardiac Surgery, J. Leff, A. Rhee, S. Nair, D. Lazar, S. Sathyanarayana, L. Shore-Lesserson

Journal Articles

© 2019 Annals of Cardiac Anaesthesia. Objectives: To compare the effectiveness of epsilon aminocaproic acid (EACA) to tranexamic acid (TA) in reducing blood loss and transfusion requirements in patients undergone cardiac surgery under cardiopulmonary bypass. Design: Randomized, double blinded study. Outcome variables collected included; baseline demographic characteristics, type of surgery, amount of 24 hour chest tube drainage, amount of 24 hour blood products administered, 30 day mortality and morbidity and length of stay. We analyzed the data using parametric and non-parametric tests as appropriate. Setting: Single center tertiary-care university hospital setting. Participants: 114 patients who had undergone cardiac surgery under …


Anticoagulation Management And Heparin Resistance During Cardiopulmonary Bypass: A Survey Of Society Of Cardiovascular Anesthesiologists Members, R. M. Sniecinski, E. Bennett-Guerrero, L. Shore-Lesserson 2019 Zucker School of Medicine at Hofstra/Northwell

Anticoagulation Management And Heparin Resistance During Cardiopulmonary Bypass: A Survey Of Society Of Cardiovascular Anesthesiologists Members, R. M. Sniecinski, E. Bennett-Guerrero, L. Shore-Lesserson

Journal Articles

We surveyed Society of Cardiovascular Anesthesiologists members regarding anticoagulation practices for cardiopulmonary bypass and attitudes on heparin resistance. Of 550 respondents (18.5% response rate), 74.9% (95% CI, 71.3%-78.5%) used empiric weight-based dosing of heparin, and 70.7% (95% CI, 66.9%-74.5%) targeted an activated clotting time of either 400 or 480 seconds to initiate cardiopulmonary bypass. Of note, 17.1% (95% CI, 13.9%-20.2%) of respondents reported activated clotting time targets lower than those recommended by recent 2018 Society of Thoracic Surgeons/Society of Cardiovascular Anesthesiologists/American Society of Extracorporeal Technology guidelines or failed to monitor heparin effects at all. When heparin resistance was encountered, 54.2% …


Assessment Of Volume Status During Prone Spine Surgery Via A Novel Point-Of-Care Ultrasound Technique, Jeremy Hensley, Hong Wang 2019 Ruby Memorial Hospital · Morgantown, USA

Assessment Of Volume Status During Prone Spine Surgery Via A Novel Point-Of-Care Ultrasound Technique, Jeremy Hensley, Hong Wang

Faculty & Staff Scholarship

Background Operations performed with the patient in the prone position can pose a significant challenge to the anesthesiologist. Hypotension is a commonly encountered complication. Intravascular volume depletion and decreased cardiac output secondary to decreased preload are thought to be the most likely cause of hypotension in the prone position. Measurement of inferior vena cava (IVC) diameter via point-of-care ultrasound examination (POC_US) has been used to provide an estimate of intravascular volume status. However, this measurement is most often obtained with the patient in the supine position. Materials and methods In this study, we describe a technique for evaluating IVC diameter …


Master Of Science In Anesthesia Fort Lauderdale, Nova Southeastern University 2019 Nova Southeastern University

Master Of Science In Anesthesia Fort Lauderdale, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.


Valve-In-Valve Trans Catheter Mitral Valve Replacement In A Patient With An In-Situ Valve And Tricuspid Ring, Joseph Krepp, Farzad Najam, Jonathan Reiner, K. Gage Parr 2019 George Washington University

Valve-In-Valve Trans Catheter Mitral Valve Replacement In A Patient With An In-Situ Valve And Tricuspid Ring, Joseph Krepp, Farzad Najam, Jonathan Reiner, K. Gage Parr

Anesthesiology and Critical Care Medicine Faculty Posters and Presentations

No abstract provided.


Caring For The Care‐Giver: Debriefing Following Intra‐Operative Death, Roy Soto, Julie Kado, Bryan Kerner, Paul O’Leary, Gerald Rosen 2019 Beaumont Health

Caring For The Care‐Giver: Debriefing Following Intra‐Operative Death, Roy Soto, Julie Kado, Bryan Kerner, Paul O’Leary, Gerald Rosen

Articles

Introduction: Intraoperative death affects a team of individuals, each with different levels of training and experience. Although briefings, time-outs, and debriefings have been well described, it is unclear how often they occur following intraoperative catastrophic events. We utilized an electronic survey to assess the frequency and potential utility of a formal debriefing process following the intraoperative death of a patient, and discuss our findings in light of the mental well-being of perioperative medical personnel. Methods:A 19 question electronic survey was distributed to primary operating room staff in two hospital systems. The survey was designed to identify which OR staff members …


Chronic Post Mastectomy Pain In Adult Female Patients At Aga Khan University Hospital Nairobi, Jared Owour Mbete 2019 Aga Khan University

Chronic Post Mastectomy Pain In Adult Female Patients At Aga Khan University Hospital Nairobi, Jared Owour Mbete

Master of Medicine in Anaesthesiology

Introduction: Breast cancer is a major cause of morbidity and mortality worldwide among women. The improvement in diagnostic and treatment strategies has led to a larger number of survivors who have breast cancer. However, there are complications attributed to breast cancer treatments, including chronic post mastectomy pain (CPMP). CPMP causes physical, social, emotional and functional disability. Once established, it is difficult to treat and negatively impact quality of life of the affected patients. Despite the big number of patients with breast cancer who undergo mastectomy at AKUHN, the burden of CPMP and factors associated with it remain unknown. Objectives: To …


The Effect Of Saline Flush After Rocuronium Bolus On The Proportion Of Patients With Excellent Intubating Conditions In Adult Patients Undergoing Elective Surgery At Akuh-N, Ian Odari 2019 Aga Khan University

The Effect Of Saline Flush After Rocuronium Bolus On The Proportion Of Patients With Excellent Intubating Conditions In Adult Patients Undergoing Elective Surgery At Akuh-N, Ian Odari

Master of Medicine in Anaesthesiology

Background: In emergency surgeries requiring endotracheal intubation, the time to effect of neuromuscular blocking drugs is a crucial time in which patients are predisposed to hypoxia and aspiration into the lungs. Various strategies have been undertaken to shorten this time, including the timing and the priming techniques, dose changes and use of a flush following the muscle relaxant. All these methods had positive results but some are associated with side effects. The effectiveness of a muscle relaxant can either be assessed using the train of four or intubating conditions on the Goldberg scale. In this study, the plan is to …


The Effect Of Premedication With Intravenous Lornoxicam On Propofol Injection Pain At Induction Of General Anaesthesia In Adults: A Randomised Placebo-Controlled Trial, Dennis Omari Onyancha 2019 Aga Khan University

The Effect Of Premedication With Intravenous Lornoxicam On Propofol Injection Pain At Induction Of General Anaesthesia In Adults: A Randomised Placebo-Controlled Trial, Dennis Omari Onyancha

Master of Medicine in Anaesthesiology

Background: Propofol is widely used for the induction and maintenance of general anaesthesia and offers many key attractive pharmacological qualities that make it suitable for these indications. However, pain on injection is one of its major drawbacks and can be very distressing to patients. There is a paucity of studies that have looked at the effect of lornoxicam on propofol injection pain either as a sole intervention or in combination with any other method. Primary objective: To determine whether premedication with intravenous lornoxicam had any effect on the intensity of propofol injection pain at induction of general anaesthesia in adult …


Cash Transfers And Hiv/Hsv-2 Prevalence: A Replication Of A Cluster Randomized Trial In Malawi, Lynette M. Smith, Nicholas A. Hein, Danstan Bagenda 2019 University of Nebraska Medical Center

Cash Transfers And Hiv/Hsv-2 Prevalence: A Replication Of A Cluster Randomized Trial In Malawi, Lynette M. Smith, Nicholas A. Hein, Danstan Bagenda

Journal Articles: Anesthesiology

INTRODUCTION: In this paper we perform a replication analysis of "Effect of a cash transfer programme for schooling on prevalence of HIV and herpes simplex type 2 in Malawi: a cluster randomised trial" by Sarah Baird and others published in "The Lancet" in 2012. The original study was a two-year cluster randomized intervention trial of never married girls aged 13-22 in Malawi. Enumeration areas were randomized to either an intervention involving cash transfer (conditional or unconditional of school enrollment) or control. The study included 1708 Malawian girls, who were enrolled at baseline and had biological testing for HIV and herpes …


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