Biomechanical Engineering Commons^™

Pediatric Blood Calculator, Richard Desatnik

Williams Honors College, Honors Research Projects

This paper outlines an expert system based solution for calculating the optimal amount of blood draw from infants to carry out critical tests requested by the attending clinicians. The solution is a hand-held device with a user-friendly interface that allows a meaningful two-way conversation between the clinician and the pathology office. Based on the tests being requested, the calculator determines the minimum amount of blood required in the different vials based on a smart expert system. This removes the uncertainty that is prevalent today in the amount of blood required to do all the tests, since in some cases there …

The Tera Multi Terrain Mobility Aid Chassis, Colton Kemp, Daniel Nicoll, Ibrahim Suleiman, Mohammad Alyami

Williams Honors College, Honors Research Projects

The natural environment poses a significant number of obstacles and dynamic settings that makes mobility difficult for those with physical and mobility impairments. To approach this problem, a suspension was designed using inspiration from the early Mars rovers developed by NASA for traversing the varied Martian landscape. The course of the project followed the direction of a start-up through problem identification, early design generation and review, and final design production. The project outcome, through client request and proven market research, aimed to produce a multi-terrain wheelchair. The final product is a kinematic body with mobile front “legs” and a rotational …

Integrated Dentistry Face Shield, Noah Glass

Williams Honors College, Honors Research Projects

Currently, the United States and the entire world is experiencing a global pandemic that has drastically changed the way we go about our everyday lives. Dr. Pavlik, a local dentist is one such person who has had to alter his normal dentistry routine to one of extreme caution while working on patients. His day to day job puts him at a high risk of being exposed to Covid-19 by actively working in patients’ mouths at proximity. Dr. Pavlik’s current dentistry equipment is lackluster in its compatibility with his safety equipment. To help minimize exposure to Covid-19 for Dr. Pavlik and …

Enhancement Of The Syncardia Total Artificial Heart For Pediatric Use, Margaret Clark, Madison Marks

Williams Honors College, Honors Research Projects

Pediatric patients with disorders and diseases of the heart have limited options with regards to implantable devices. Many of these implants are ventricular assist devices, which is not always suitable for a patient. Total artificial hearts (TAHs) have supported many adult patients until transplantation, and we believe that they could do the same for pediatric patients. SynCardia has the only Food and Drug Administration (FDA) approved TAH devices. Since SynCardia is the only company with FDA approved TAHs, we decided to modify the design of the SynCardia TAH for use in pediatric patients without compromising the function of the current …

Quantification And Modeling Of Bladder Biomechanics Mechanisms Linking Spontaneous Rhythmic Contractions And Dynamic Elasticity To Detrusor Overactivity, Zachary E. Cullingsworth

Theses and Dissertations

Overactive bladder (OAB) is a chronic condition affecting approximately 20% of adults in the United States. Detrusor overactivity (DO) is the presence of non-voiding contractions in the detrusor (bladder) muscle during filling and is present in some individuals with OAB. DO is currently identified visually during a urodynamics (UD) study involving pressure catheters and filling and voiding of the bladder to evaluate function. UD provides limited subtyping of DO, and an incomplete understanding of mechanisms contributing to OAB.

Aim 1 of this study was to develop objective tools to quantify, subgroup and better understand …

In Vivo Data Capture Using Hssr For Calibration Of Computational Models, Thor Erik Andreassen

Electronic Theses and Dissertations

Computational modeling is a vital tool for understanding and evaluating healthy and unhealthy function of the musculoskeletal aspects of the human body. However, the accuracy of the musculoskeletal models depends significantly on the accuracy of the input data used to calibrate various behavioral parameters of the model. To date, most computational models have been built using generic in vitro data, mostly because of a lack of accurate and meaningful datasets from in vivo testing. The next major step in computational modeling is to create subject-specific computational models using calibration data taken from in vivo testing. The overall goal was to …

The Effects And Analysis Of Implant Type And Surgical Approach In Total Hip Arthroplasty Dislocation Resistance, Brittany Marshall

Electronic Theses and Dissertations

Total hip arthroplasty (THA) is one of the most successful orthopaedic surgeries performed, in which the hip joint is reconstructed to decrease pain and to improve the functionality to the joint. Although these surgeries are very successful, there still remain areas for improvement, such as failures due to instability and dislocation of the implanted joint. The purpose of this thesis is to investigate the effect of surgical entrance approach on dislocation, the effect of implant type, and the effect of capsule repair and closure. The need to quantify the resistance to dislocation is important in understanding the effect that each …

Seismocardiography - Genesis, And Utilization Of Machine Learning For Variability Reduction And Improved Cardiac Health Monitoring, Peshala Thibbotuwawa Gamage

Electronic Theses and Dissertations, 2020-2023

Seismocardiography (SCG) is the measured chest surface vibrations resulting from cardiac activity. Although SCG can contain information that correlate with cardiac health, its utility may be limited by lack of understanding of the signal genesis and a variability that can mask subtle SCG changes. The current research utilized medical imaging reconstruction and finite element method (FEM) to simulate SCG by modeling the propagation of myocardial movements to the chest surface. FEM analysis provided a link between myocardial movements and the SCG signals measured at the chest surface and suggested that myocardial movement is a primary source of SCG. Increased understanding …

Automated And Standardized Tools For Realistic, Generic Musculoskeletal Model Development, Trevor Rees Moon

Graduate Theses, Dissertations, and Problem Reports (ETD)

Human movement is an instinctive yet challenging task that involves complex interactions between the neuromusculoskeletal system and its interaction with the surrounding environment. One key obstacle in the understanding of human locomotion is the availability and validity of experimental data or computational models. Corresponding measurements describing the relationships of the nervous and musculoskeletal systems and their dynamics are highly variable. Likewise, computational models and musculoskeletal models in particular are vitally dependent on these measurements to define model behavior and mechanics. These measurements are often sparse and disparate due to unsystematic data collection containing variable methodologies and reporting conventions. To date, …

Evaluation Of Control Strategies For Overhead Work Using Electromyography Of Rotator Cuff Muscles, Hossein Motabar

Graduate Theses, Dissertations, and Problem Reports (ETD)

Work-related musculoskeletal disorders (MSDs) of shoulder have a significant impact on overall health and economics in the industrialized nations. Rotator cuff is the most frequently injured region in the shoulder complex. Overhead work is considered as one of the most predominant causes of rotator cuff injuries. The workers in construction, automotive, and aerospace industries are routinely exposed to overhead exertions. Elimination of overhead work is nearly impossible due to various task and technology constraints. Therefore, appropriate intervention strategies based on the engineering and administrative controls opt to be used to prevent the hazardous impact of overhead exertions. The objective of …

An Extensive Set Of Kinematic And Kinetic Data For Individuals With Intact Limbs And Transfemoral Prosthesis Users, Seyed Abolfazl Fakoorian, Arash Roshanineshat, Poya Khalaf, Vahid Azimi, Daniel J. Simon, Elizabeth Hardin

Electrical and Computer Engineering Faculty Publications

This paper introduces an extensive human motion data set for typical activities of daily living. These data are crucial for the design and control of prosthetic devices for transfemoral prosthesis users. This data set was collected from seven individuals, including five individuals with intact limbs and two transfemoral prosthesis users. These data include the following types of movements: (1) walking at three different speeds; (2) walking up and down a 5-degree ramp; (3) stepping up and down; (4) sitting down and standing up. We provide full-body marker trajectories and ground reaction forces (GRFs) as well as joint angles, joint velocities, …

Binder Saturation, Layer Thickness, Drying Time And Their Effects On Dimensional Tolerance And Density Of Cobalt Chrome - Tricalcium Phosphate Biocomposite, John Ruprecht

All Graduate Theses, Dissertations, and Other Capstone Projects

Traditional metals such as stainless steel, titanium and cobalt chrome are used in biomedical applications (implants, scaffolds, etc.) but suffer from issues such as osseointegration and compatibility with existing bone. One way to improve traditional biomaterials is to incorporate ceramics with these metals so that their mechanical properties can be similar to cortical bones. Tricalcium phosphate is such a ceramic with properties such that it can be used in the human body. This research explores the use of the Binder Jetting based additive manufacturing process to create a novel biocomposite made of cobalt chrome and tricalcium phosphate. Experiments were conducted …

Efficacy Of Hard Hats In Attenuating Head Accelerations: A Combined Experimental And Computational Investigation, Arthur Aloisio Alves Dos Santos

UNF Graduate Theses and Dissertations

Struck-by accidents are a leading cause of traumatic brain injuries in the construction industry. While hard hats are the conventional means of industrial head protection, the current test standard to evaluate hard hat performance does not assess their ability to mitigate head accelerations from such impacts. To address this gap in knowledge, three investigations were pursued as part of this thesis. First, a variety of commercially available hard-hat designs – differentiated by shell design, number of suspension points, and suspension tightening system – were tested for their ability to attenuate accelerations during vertical impacts to the head. All hard-hats appreciably …

Effects On Initial Fixation Of Cementless Tibial Trays In Total Knee Arthroplasty, Brooke Fritts Thompson

Electronic Theses and Dissertations

Bone mineral density (BMD), among other factors, largely effect the initial stability of the cementless tibial tray component in a total knee replacement (TKR), where increased motion at the tray-bone interface hinders bony ingrowth. With a lack of bony ingrowth, the cementless implant will not experience long-term success. Understanding which factors influence initial stability yields insight into surgical technique considerations and help inform a surgeon’s implant choice. The objective of this study was to evaluate factors influencing the initial stability of cementless tibial trays using a 6-degree of freedom (6-DOF) robotic joint simulator, the AMTI VIVO, and combined loading scenarios …

Investigation Of Vapor Deposited Conduction Seed Layer For Electrodeposition On Polymers, Olivia Bray

UNF Graduate Theses and Dissertations

The use of three-dimensional printing (3d printing) technologies are becoming increasingly popular in today’s society due to the time and cost advantages associated with these processes. In industries with a high demand for customizable and one-of-a-kind parts at a low volume, these additive manufacturing processes offer a promising solution. Surgical devices are a great example of this demand. Despite the advantages offered by 3d printing, the mechanical integrity of these 3d printed parts are often not comparable to the solid metal parts that have historically been used. In an effort to create a superior part and reach operational requirements, reinforcement …

Isolated Nucleus Stiffens In Response To Low Intensity Vibration, Joshua Newberg

Boise State University Theses and Dissertations

The nucleus, central to all cellular activity, relies on both direct mechanical input and its molecular transducers to sense and respond to external mechanical stimuli. This response occurs by regulating intra-nuclear organization that ultimately determines gene expression to control cell function and fate. It has long been known that signals propagate from an extracellular environment to the cytoskeleton and into nucleus (outside-in signaling) to regulate cell behavior. Emerging evidence, however, shows that both the cytoskeleton and the nucleus have inherent abilities to sense and adapt to mechanical force, independent of each other. While it has been shown that isolated nuclei …

Development And Characterization Of A Biopolymer Direct-Write Process For 3d Microvascular Structures Formation., Xiaoming Fan

Electronic Theses and Dissertations

Engineering of bulk tissues has been limited by the lack of nutrient and waste exchange in these tissues without an adjacent capillary network. To produce microvasculature, a scaffold must be produced that provides temporary mechanical support and stimulate endothelial cell adhesion, growth, and morphogenesis into a vessel. However, current well-established techniques for producing microvasculature, such as electrospinning, are limited since they lack both the precision to control fiber placement in three-dimensional space and the ability to create fiber networks with predefined diameters to replicate the physiological microvascular progression from arteriole to capillary to venule. Our group has developed a “Direct-write” …

Katie's Jogger, Megan Guillermo, Erin Wint, Abdullah Sulaiman, Kathryn Mangiaracina

Mechanical Engineering

Edward Robinson is an avid runner who would like to take his daughter on runs. His daughter, Katie, is 100% wheelchair bound and currently does not fit in any commercial joggers on the market. The project team was expected to design, build, and test a custom working prototype of a jogger that the sponsor can use to take his daughter on runs. This entire project was performed over a span of three quarters.

Vibration Evaluation Of The Driver’S Seat Of Mf 285 Tractor In Conducting The Tillage Operations, Gholamhossein Shahgholi, Sedagat Fazeli, Saleh Harami Mousavi

Emirates Journal for Engineering Research

The purpose of this study was to investigate the effect of the tractor speed on the tractors’ seat vibration and to assess the level of comfort of the driver during the agricultural operation using moldboard and disc plows. Experiments were conducted on sandy loamy soil in a factorial experiment based on randomized complete block design with three replications. The effect of the type of tillage implement using the moldboard and disc plows, the velocity of advance in four levels of 4.5, 6 and 8.8 km/h and vibration was measured and evaluated at three directions of longitudinal (x), lateral (y) and …

Estimation Of Gait Kinematics And Kinetics From Inertial Sensor Data Using Optimal Control Of Musculoskeletal Models, Eva Dorschky, Marlies Nitschke, Ann-Kristin Seifer, Antonie J. Van Den Bogert, Bjoern M. Eskofier

Mechanical Engineering Faculty Publications

Inertial sensing enables field studies of human movement and ambulant assessment of patients. However, the challenge is to obtain a comprehensive analysis from low-quality data and sparse measurements. In this paper, we present a method to estimate gait kinematics and kinetics directly from raw inertial sensor data performing a single dynamic optimization. We formulated an optimal control problem to track accelerometer and gyroscope data with a planar musculoskeletal model. In addition, we minimized muscular effort to ensure a unique solution and to prevent the model from tracking noisy measurements too closely. For evaluation, we recorded data of ten subjects walking …

A Novel Fiber Jamming Theory And Experimental Verification, Jared Richard Chafetz

Master's Theses

This thesis developed a novel theory of fiber jamming and experimentally verified it. The theory relates the performance, which is the ratio between the stiff and soft states of a fiber jamming chamber, to three relative design parameters: the ratio of the wall thickness to the membrane inner diameter, the ratio of the fiber diameter to membrane inner diameter, and the number of fibers. These three parameters, when held constant across different chamber sizes, hold the performance constant. To test the theory, three different types of fiber jamming chambers were built in three different sizes. Each chamber was set up …

System Integration Of C-Arm Robotic Prototype Using Motion Capture Guidance For Accurate Repositioning, Alireza Yazdanshenas

Mechanical Engineering Theses

One of the important surgical tools in spinal surgery is the C-Arm X-ray System. The C-Arm is a large “C” shaped and manually maneuvered arm that provides surgeons and X-ray technicians the ability to take quick quality X-rays during surgery. Because of its five degrees of freedom, the C-Arm can be manually maneuvered around the patient to provide many angles and perspectives, ensuring surgical success.

This system works fine for most surgical procedures but falls short when the C-Arm must be moved out of the way for complicated surgical procedures.

The aim of this thesis is to develop an accurate …

Investigation Of Fundamental Principles Of Rigid Body Impact Mechanics, Khalid Alluhydan

Mechanical Engineering Research Theses and Dissertations

In impact mechanics, the collision between two or more bodies is a common, yet a very challenging problem. Producing analytical solutions that can predict the post-collision motion of the colliding bodies require consistent modeling of the dynamics of the colliding bodies. This dissertation presents a new method for solving the two and multibody impact problems that can be used to predict the post-collision motion of the colliding bodies. Also, we solve the rigid body collision problem of planar kinematic chains with multiple contacts with external surfaces.

In the first part of this dissertation, we study planar collisions of Balls and …

Computational Analysis And Design Optimization Of Convective Pcr Devices, Jung Il Shu

Mechanical & Aerospace Engineering Theses & Dissertations

Polymerase Chain Reaction (PCR) is a relatively novel technique to amplify a few copies of DNA to a detectable level. PCR has already become common in biomedical research, criminal forensics, molecular archaeology, and so on. Many have attempted to develop PCR devices in numerous types for the purpose of the lab-on-chip (LOC) or point-of-care (POC). To use PCR devices for POC lab testing, the price must be lower, and the performance should be comparable to the lab devices. For current practices with the existing methods, the price is pushed up higher partially due to too much dependence on numerous developmental …

The Effect Of Radial Head Hemiarthroplasty Stem Fit On Radiocapitellar Contact Mechanics: Is Loose Fit Better Than Rigidly Fixed?, Jakub Szmit, Graham J.W. King, James A. Johnson, G. Daniel G. Langohr

Western Research Forum

Background/Methods: Radial head hemiarthroplasty is commonly employed to manage comminuted displaced fractures. With regards to implant fixation, current designs vary with some prostheses aiming to achieve a tight 'fixed' fit, and others utilizing a smooth stem with an over reamed 'loose' fit. The purpose of the present study was to evaluate the effect of radial head hemiarthroplasty stem fit on radiocapitellar contact using a finite element model which simulated both fixed (size-for-size) and loose (1, 2 & 3mm over reamed) stem fits.

Hypothesis: It was hypothesized that a loose stem fit would improve radiocapitellar contact mechanics, with increased contact area …

Investigating The Effect Of Stiffness In Hemiarthroplasty Implants, Carolyn Berkmortel, Daniel Langohr, Graham King, James Johnson

Western Research Forum

Background: Hemiarthroplasty is an attractive alternative to total arthroplasty because it conserves tissue, allows for quicker recovery, and has a lower cost. However, likely due to the high stiffness of the implant, hemiarthroplasties often lead to accelerated wear of the opposing native cartilage.

Hypothesis and Methods: The purpose of this study was to investigate the maximum contact stress on the capitellum for different currently available biomaterials in radial head hemiarthroplasty and compare them to the native radial head. A finite element model was developed in ABAQUS (Dassault Systèmes Simulia Corp., RI, USA). An axial load of 100N was applied to …

A Soft-Robotic Harbor Porpoise Pectoral Fin Driven By Coiled Polymer Actuators As Artificial Muscles, Robert Hunt, Sarah Trabia, Zakai Olsen, Kwang Kim

Mechanical Engineering Faculty Research

Biomimicry is an approach in science and engineering to overcome human challenges by designing materials and systems modeled after nature. Selected applications of biomimicry include catheters, hearing devices, and artificial appendages such as arms, legs, and fingers. The inspiration for this study is the hydrofoil-like structured pectoral fin of the harbor porpoise whale that is ultimately useful for studying fluid-structure interactions, drag, lift, and laminar-to-turbulent transitions. The pectoral fin is fabricated by manipulating computed tomography (CT) scans into 3D models using Simpleware ScanIP and post-processed in Autodesk for printing. An array of thermally driven coiled polymer actuators (CPA) fabricated from …

Cooking Hand Multi-Tool, Amanda D. Meares, Amy H. Wilson, Ethan G. Littlejohn, Duania A. Evans

Biomedical Engineering

The purpose of this project was to devise a solution for Jorge Segura, a US Marine who was wounded in Afghanistan and had to have his non-dominant arm amputated above the elbow. His current prosthetic attachments are not suited to cooking tasks, so he needed a way to cook more effectively with either prosthetic attachments or accessibility devices. The main tasks that he needed help with was holding down food on cutting boards and stabilizing pots, pans, and bowls especially when stirring. After background research, exploring commercially available devices, and talking with our challenger, our solution was to design three …

Adapted Trailer Hitching System, Joseph Neil Hearn, Maxwell M. Selna, Maximilian D. Cossalter, Eric B. Ringsrud

Mechanical Engineering

This report highlights the entire design process of an adapted trailer hitching system for Taylor Morris: a navy veteran and quadruple amputee. This begins with problem definition through customer and product research. Objectives are generated after the problem is defined and the boundary of the project is set. This outcome of the project focuses on modifications/improvements to the vehicle side of the problem and leaves the trailers untouched. Engineering specifications are developed to constrain the concept design direction, which ultimately dictates the outcome of the final design. The final design is used as a basis to manufacture a structural prototype …

Sand Foot: A Prosthesis For Walking On Sand, Samantha A. Galicinao, John Dewing, Daniel Dugan Dotson, Christopher Urasaki

Biomedical Engineering

This critical design report describes the product development of a prosthesis for use on sand. Quality of Life Plus (QL+), a national non-profit organization aimed to develop prostheses for veterans and people with disabilities, introduced this project and its accompanying challenger, Sgt. Brady, to Cal Poly’s Interdisciplinary Senior Project class in September 2018. After consulting with Sgt. Brady and QL+ and performing extensive research, the Sand Foot team defined customer requirements and engineering specifications to meet these requirements. Comfortability, durability, and sandproof were key customer requirements. Several conceptual models were brainstormed and a final design was selected based on the …