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Articles 81601 - 81630 of 659022

Full-Text Articles in Social and Behavioral Sciences

Understanding The Impact Of Emotional Support On Mental Health Resilience Of The Community In The Social Media In Covid-19 Pandemic, Xuan Hu, Yanqing Song, Ruilin Zhu, Shuang He, Bowen Zhou, Xuelian Li, Han Bao, Shan Shen, Bingsheng Liu Jul 2022

Understanding The Impact Of Emotional Support On Mental Health Resilience Of The Community In The Social Media In Covid-19 Pandemic, Xuan Hu, Yanqing Song, Ruilin Zhu, Shuang He, Bowen Zhou, Xuelian Li, Han Bao, Shan Shen, Bingsheng Liu

Research Collection Lee Kong Chian School Of Business

Background: Emotional support in social media can act as a buffer against the negative impact of affective disorders. However, empirical evidence relating to emotional support in social media and how it influences the wider public remains scanty. The objective of this study is therefore to conduct a prototype investigation into the translation mechanism of emotional support in social media, providing empirical evidence for practitioners to use to tackle mental health issues for the wider public. Methods: A regression model is proposed to examine the relationship between perceived and received emotional support. Received emotional support is set as the dependent variable …


Gamifying An Assessment Method: What Signals Are Organizations Sending To Applicants?, Konstantina Georgiou, Filip Lievens Jul 2022

Gamifying An Assessment Method: What Signals Are Organizations Sending To Applicants?, Konstantina Georgiou, Filip Lievens

Research Collection Lee Kong Chian School Of Business

Purpose: The paper aims to expand the authors' knowledge on gamification and the signals sent on behalf of the organization when gamified assessments are used. The authors examine the mechanisms through which the use of gamification into an assessment method may increase the attractiveness of an organization as a prospective employer. Design/methodology/approach: The first study examines, following a longitudinal design, the signals that an organization sends to applicants about the organization's symbolic traits (e.g. innovativeness), through the characteristics of a gamified assessment, in terms of enjoyment and flow and impact on organizational attractiveness. Upon clarifying this mechanism, the second study …


What, Why And How Financial Development Matters: Evidence Of Asean-5, Asia-5 And Oecd-7 Economies, Swee Liang Tan Jul 2022

What, Why And How Financial Development Matters: Evidence Of Asean-5, Asia-5 And Oecd-7 Economies, Swee Liang Tan

Research Collection School Of Economics

This paper analyzed the association between bank and capital markets financial development with income per capita in three regions; ASEAN-5 economies (Singapore, Malaysia, Thailand, Philippines, Indonesia), Asia-5 (Japan, China, Hong Kong SAR, South Korea, and India), and OECD-7 (Australia, Canada, Denmark, Norway, Sweden, UK, and US) from 2000 to 2017 using panel data regressions. A key lesson ASEAN-5 can learn from Asia-5 and OECD-7 experience is that bank size does matter despite digital disruptions to their banking system; yet large financial structure that favors banks is negatively associated with Asia-5, and importantly, efficient banking system (not bank size alone) is …


Values Assessment For Personnel Selection: Comparing Job Applicants To Non-Applicants, Jeromy Anglim, Karlyn Molloy, Patrick D. Dunlop, Simon L. Albrecht, Filip Lievens, Marty Andrew Jul 2022

Values Assessment For Personnel Selection: Comparing Job Applicants To Non-Applicants, Jeromy Anglim, Karlyn Molloy, Patrick D. Dunlop, Simon L. Albrecht, Filip Lievens, Marty Andrew

Research Collection Lee Kong Chian School Of Business

Some scholars suggest that organizations could improve their hiring decisions by measuring the personal values of job applicants, arguing that values provide insights into applicants’ cultural fit, retention prospects, and performance outcomes. However, others have expressed concerns about response distortion and faking. The current study provides the first large-scale investigation of the effect of the job applicant context on the psychometric structure and scale means of a self-reported values measure. Participants comprised 7,884 job applicants (41% male; age M = 43.32, SD = 10.76) and a country-, age-, and gender-matched comparison sample of 1,806 non-applicants (41% male; age M = …


Beyond The High Ground: A Taxonomy For Earth-Moon System Operations, Adam P. Wilmer, Robert A. Bettinger Jul 2022

Beyond The High Ground: A Taxonomy For Earth-Moon System Operations, Adam P. Wilmer, Robert A. Bettinger

Faculty Publications

Situational and space domain awareness in the space domain can no longer be confined to that which is found in geosynchronous orbit. International activities—commercial and military—and threats to the planet itself exist and are increasing across the entire Earth-Moon system. This reality requires a new taxonomy to accurately classify space domain awareness missions and better apply resources to and development of the same. This work presents such a taxonomy for the classification of space domain awareness regions.


Aligning The Transit Industry And Their Vendors In The Face Of Increasing Cyber Risk: Recommendations For Identifying And Addressing Cybersecurity Challenges, Scott Belcher, Terri Belcher, Kathryn Seckman, Brandon Thomas, Homayun Yaqub Jul 2022

Aligning The Transit Industry And Their Vendors In The Face Of Increasing Cyber Risk: Recommendations For Identifying And Addressing Cybersecurity Challenges, Scott Belcher, Terri Belcher, Kathryn Seckman, Brandon Thomas, Homayun Yaqub

Mineta Transportation Institute

Public transit agencies in the United States depend on external vendors to help deliver and maintain many essential services and to provide critical technologies, from ticket purchases to scheduling to email management. While the integration of new, advanced technologies into the public transit industry brings important advancements to U.S. critical transportation infrastructure, the application of digital technologies also brings with it a new assortment of digital risks. Transit agencies of all sizes are finding themselves subject to cyber incidents—most notably ransomware attacks—like those experienced by larger, more prominent companies and critical infrastructure providers. The findings in this report focus on …


Analyzing The Use And Impacts Of Oakland Slow Streets And Potential Scalability Beyond Covid-19, Gordon Douglas, David Moore Jul 2022

Analyzing The Use And Impacts Of Oakland Slow Streets And Potential Scalability Beyond Covid-19, Gordon Douglas, David Moore

Mineta Transportation Institute

This report presents the results of a mixed-methods study of the 2020-2022 Oakland Slow Streets program. An official response to the Covid-19 pandemic, the program used signs and temporary barricades to limit thru-traffic on 21 miles of city streets to create more and safer space for walking, cycling, and outdoor recreation. Researchers collected data throughout the summer of 2021 on seven designated slow streets plus one cross street and one control street for each – a total of 21 street segments representing conditions in seven different neighborhoods across Oakland. Data collection comprised in-person passerby counts, observations and photographs of local …


Managing The Curb: Understanding The Impacts Of On-Demand Mobility On Public Transit, Micromobility, And Pedestrians, Susan Shaheen, Elliot Martin, Adam Cohen, Jacquelyn Broader, Richard Davis Jul 2022

Managing The Curb: Understanding The Impacts Of On-Demand Mobility On Public Transit, Micromobility, And Pedestrians, Susan Shaheen, Elliot Martin, Adam Cohen, Jacquelyn Broader, Richard Davis

Mineta Transportation Institute

In recent years, innovative mobility and shifts in travel and consumption behavior are changing how people access and use the curb. Shared mobility—the shared use of a vehicle, bicycle, scooter, or other mode—coupled with outdoor dining, curbside pick-up, and robotic delivery are creating new needs related to the planning, management, and enforcement of curb access. This study examines curb planning and management from several angles, such as safety, social equity, and multimodal connections. This research employs a multi-method approach to identify the changing needs for curb space management and how to meet these needs through new planning and implementation policies …


A Validation Framework For Somatic Copy Number Detection In Targeted Sequencing Panels, Raghu Chandramohan, Jacquelyn Reuther, Ilavarasi Gandhi, Horatiu Voicu, Karla R Alvarez, Sharon E Plon, Dolores H Lopez-Terrada, Kevin E Fisher, D Williams Parsons, Angshumoy Roy Jul 2022

A Validation Framework For Somatic Copy Number Detection In Targeted Sequencing Panels, Raghu Chandramohan, Jacquelyn Reuther, Ilavarasi Gandhi, Horatiu Voicu, Karla R Alvarez, Sharon E Plon, Dolores H Lopez-Terrada, Kevin E Fisher, D Williams Parsons, Angshumoy Roy

Center for Medical Ethics and Health Policy Staff Publications

Somatic copy number alterations (SCNAs) in tumors are clinically significant diagnostic, prognostic, and predictive biomarkers. SCNA detection from targeted next-generation sequencing panels is increasingly common in clinical practice; however, detailed descriptions of optimization and validation of SCNA pipelines for small targeted panels are limited. This study describes the validation and implementation of a tumor-only SCNA pipeline using CNVkit, augmented with custom modules and optimized for clinical implementation by testing reference materials and clinical tumor samples with different classes of copy number variation (CNV; amplification, single copy loss, and biallelic loss). Using wet-bench and in silico methods, various parameters impacting CNV …


Entering Dystopia: Should Your Face Be The Key To Your Fate?, Shilpa Madan, Krishna Savani, Gita V. Johar Jul 2022

Entering Dystopia: Should Your Face Be The Key To Your Fate?, Shilpa Madan, Krishna Savani, Gita V. Johar

Research Collection Lee Kong Chian School Of Business

How would you feel if you were rejected from a job because you didn't look competent enough? Or if you were apprehended at a public place by the police because you looked like a criminal? Although these scenes sound dystopic and generate a sense of fear and anxiety, technology that claims that people's traits can be inferred from their faces already exists and is being used by businesses and governments worldwide.


Exploring The Empirical Relationship Between Inner-City Blight And Urban Sprawl In The United States, Eric Fesselmeyer, Kiat Ying Seah Jul 2022

Exploring The Empirical Relationship Between Inner-City Blight And Urban Sprawl In The United States, Eric Fesselmeyer, Kiat Ying Seah

Research Collection College of Integrative Studies

Urban blight has been found to cause a variety of problems, including negatively affecting the value of surrounding properties and increasing neighborhood crime rates. If the same externalities that give rise to urban sprawl also contribute to urban blight, as is suggested by Brueckner and Helsley (2011), city center vacancy rates-an indication of blight-would increase with the extent of urban sprawl. This study adds to the sparse literature on the empirical relationship between urban sprawl and blight by finding that the city-center census tract vacancy rate is higher in more sprawling cities. The results of this article, therefore, provide support …


Provider Perceptions Of Telehealth And In-Person Exposure And Response Prevention For Obsessive-Compulsive Disorder, Andrew D Wiese, Kendall N Drummond, Madeleine N Fuselier, Jessica C Sheu, Gary Liu, Andrew G Guzick, Wayne K Goodman, Eric A Storch Jul 2022

Provider Perceptions Of Telehealth And In-Person Exposure And Response Prevention For Obsessive-Compulsive Disorder, Andrew D Wiese, Kendall N Drummond, Madeleine N Fuselier, Jessica C Sheu, Gary Liu, Andrew G Guzick, Wayne K Goodman, Eric A Storch

Center for Medical Ethics and Health Policy Staff Publications

Until recently, psychotherapies, including exposure and response prevention (ERP) for obsessive-compulsive disorder (OCD), have primarily been delivered in-person. The COVID-19 pandemic required OCD providers delivering ERP to quickly transition to telehealth services. While evidence supports telehealth ERP delivery, limited research has examined OCD provider perceptions about patient characteristics that are most appropriate for this modality, as well as provider abilities to identify and address factors interfering with effective telehealth ERP. In the present study, OCD therapists (N = 113) rated the feasibility of delivering telehealth ERP relative to in-person for different (1) patient age-groups, (2) levels of OCD severity, and …


Breast Cancer Diagnosis And Treatment During The Covid-19 Pandemic In A Nationwide, Insured Population, Jennifer L Caswell-Jin, Maryam N Shafaee, Lan Xiao, Mina Liu, Esther M John, Melissa L Bondy, Allison W Kurian Jul 2022

Breast Cancer Diagnosis And Treatment During The Covid-19 Pandemic In A Nationwide, Insured Population, Jennifer L Caswell-Jin, Maryam N Shafaee, Lan Xiao, Mina Liu, Esther M John, Melissa L Bondy, Allison W Kurian

Center for Medical Ethics and Health Policy Staff Publications

Purpose: The early months of the COVID-19 pandemic led to reduced cancer screenings and delayed cancer surgeries. We used insurance claims data to understand how breast cancer incidence and treatment after diagnosis changed nationwide over the course of the pandemic.

Methods: Using the Optum Research Database from January 2017 to March 2021, including approximately 19 million US adults with commercial health insurance, we identified new breast cancer diagnoses and first treatment after diagnosis. We compared breast cancer incidence and proportion of newly diagnosed patients receiving pre-operative systemic therapy pre-COVID, in the first 2 months of the COVID pandemic and in …


United States Healthcare Burden Of Pediatric Functional Gastrointestinal Pain Disorder Hospitalizations From 2002 To 2018, John M Hollier, Jason L Salemi, Robert J Shulman Jul 2022

United States Healthcare Burden Of Pediatric Functional Gastrointestinal Pain Disorder Hospitalizations From 2002 To 2018, John M Hollier, Jason L Salemi, Robert J Shulman

Faculty, Staff and Students Publications

BACKGROUND: The healthcare burden of pediatric functional gastrointestinal pain disorders (FGIDs) is unclear. Our study aimed to characterize the burden of these hospitalizations in the United States (US).

METHODS: We utilized the US National Inpatient Sample from 2002 to 2018 to capture pediatric hospitalizations (ages 4 to 18 years old) with a primary discharge diagnosis of abdominal pain, constipation, irritable bowel syndrome, dyspepsia, abdominal migraine, cyclic vomiting syndrome, or fecal incontinence. We calculated the FGID hospitalization prevalence rate, length of stay (LOS), and inflation-adjusted costs annually and assessed for statistically significant trend changes using joinpoint analyses.

KEY RESULTS: 22.3 million …


Letter From Editor Jul 2022

Letter From Editor

JADARA

None


Contracting Strategies: A Different Approach To Address Long-Term Performance, Maria Calahorra-Jimenez Jul 2022

Contracting Strategies: A Different Approach To Address Long-Term Performance, Maria Calahorra-Jimenez

Mineta Transportation Institute

For cost-efficiency, public safety, and sustainability, improving long-term performance in highway projects is imperative for public administrations. Project delivery and procurement methods provide an opportunity to align design and construction processes with this goal. While previous studies have explored whether project delivery methods impact the long-term performance of highway projects, these studies did not focus on how core elements within project procurement relate to long-term performance. Thus, to fill this gap, this research explores how and to what extent long-term evaluation criteria are considered in design-build best-value procurement of highway projects. To this end, the team conducted content analysis on …


Connected Simulation For Work Zone Safety Application, Vahid Balali Jul 2022

Connected Simulation For Work Zone Safety Application, Vahid Balali

Mineta Transportation Institute

Every year, over 60,000 work zone crashes are reported in the United States (FHWA 2016). Such work zone crashes have resulted in over 4,400 fatal and 200,000 non-fatal injuries in the last 5 years (FHWA 2016, BLS 2014). Apart from the physical and emotional trauma, the annual cost of these injuries exceeds $4 million-representing significant wasted resources. To improve work zone safety, this research developed a system architecture for unveiling high-risk behavioral patterns among highway workers, equipment operators, and drivers within dynamic highway work zones. This research implemented the use of a connected virtual environment, which is an immersive hyper-realistic …


Creating Safer Communities For The Use Of Active Transportation Modes In California: The Development Of Effective Communication Message Strategy For Vulnerable Road Users, Samer Sarofim, Aly Tawfik Jul 2022

Creating Safer Communities For The Use Of Active Transportation Modes In California: The Development Of Effective Communication Message Strategy For Vulnerable Road Users, Samer Sarofim, Aly Tawfik

Mineta Transportation Institute

Despite increased efforts to improve safety in recent years (e.g., the Focus Cities Program in California), California continues to have a high rate of pedestrian and bicyclist fatalities. Currently, the state currently lacks a cohesive messaging strategy to improve behaviors related to pedestrian and cyclist traffic safety practices. To fulfill this need, this research showcases the differential effect of message framing on attitudes and intended behaviors related to pedestrian and cyclists traffic safety practices. This project investigated factors & risky behaviors contributing to accidents involving vulnerable road users, preventive measures to decrease accidents involving vulnerable road users, and more. The …


Developing A Feasible Business Model For Expanding The Ev Market To Lower Income Californians, Samer Sarofim, Aly Tawfik Jul 2022

Developing A Feasible Business Model For Expanding The Ev Market To Lower Income Californians, Samer Sarofim, Aly Tawfik

Mineta Transportation Institute

Electric vehicles (EVs) are a valuable tool in addressing the climate and energy challenges placed on our transportation systems. However, while national and international market shares of EVs have been rising with exponential rates, access to EVs of low-income populations has been significantly slower. This research developed a business model for expanding the EV market to low-income Californians. The team developed the model from qualitative data from various stakeholders, including Electric and Solar Companies, Professional and Community-Based Organizations, State Agencies, research institutions, and more, which enabled insights regarding various barriers that hinder the adoption of EVs. The team also used …


Biological Hydrogen Gas Production From Food Waste As A Sustainable Fuel For Future Transportation, Pitiporn Asvapathanagul, Leanne Deocampo, Nicholas Banuelos Jul 2022

Biological Hydrogen Gas Production From Food Waste As A Sustainable Fuel For Future Transportation, Pitiporn Asvapathanagul, Leanne Deocampo, Nicholas Banuelos

Mineta Transportation Institute

In the global search for the right alternative energy sources for a more sustainable future, hydrogen production has stood out as a strong contender. Hydrogen gas (H2) is well-known as one of the cleanest and most sustainable energy sources, one that mainly yields only water vapor as a byproduct. Additionally, H2 generates triple the amount of energy compared to hydrocarbon fuels. H2 can be synthesized from several technologies, but currently only 1% of H2 production is generated from biomass. Biological H2 production generated from anaerobic digestion is a fraction of the 1%. This study aims to enhance biological H2 production …


Design Of An Evaluation Plan For Senate Bill 1046, Maria Chierichetti, Armin Moghadam, Fatemeh Davoudi Jul 2022

Design Of An Evaluation Plan For Senate Bill 1046, Maria Chierichetti, Armin Moghadam, Fatemeh Davoudi

Mineta Transportation Institute

In an effort to understand and decrease alcohol-impaired driving as a primary collision factor In California, the research team designed an evaluation plan for California Senate Bill 1046 and its focus on ignition interlock devices as a sentence for Driving Under Influence offense. This plan will evaluate whether Senate Bill 1046 affected the Driving Under the Influence crash frequency and severity, and whether sociodemographic and geographic factors influence its effectiveness. This report lays the foundation for the evaluation that will be conducted in 2024. The research team conducted a meta-analysis of the last 12 years of literature and research on …


Manual For Asphalt Pavement Repair And Resurfacing Preparation, Dingxin Cheng, Gary Hicks, Roger D. Smith Jul 2022

Manual For Asphalt Pavement Repair And Resurfacing Preparation, Dingxin Cheng, Gary Hicks, Roger D. Smith

Mineta Transportation Institute

Timely repairs of pavement defects are essential in protecting an important investment and asset that public agencies have. These repairs may be made as durable “stand-alone” repairs of isolated problems, or as part of preparations for a total resurfacing. This manual provides basic information on the planning, materials and construction aspects of common pavement repairs such as crack sealing, crack filling, and patching, as well as a broader look at other preparations needed for total resurfacing a pavement, whether the resurfacing is a surface treatment or a thin hot mix asphalt (HMA) overlay.


Blockchain And Distributed Autonomous Community Ecosystems: Opportunities To Democratize Finance And Delivery Of Transport, Housing, Urban Greening And Community Infrastructure, William Riggs, Vipul Vyas, Menka Sethi Jul 2022

Blockchain And Distributed Autonomous Community Ecosystems: Opportunities To Democratize Finance And Delivery Of Transport, Housing, Urban Greening And Community Infrastructure, William Riggs, Vipul Vyas, Menka Sethi

Mineta Transportation Institute

This report investigates and develops specifications for using blockchain and distributed organizations to enable decentralized delivery and finance of urban infrastructure. The project explores use cases, including: providing urban greening, street or transit infrastructure; services for street beautification, cleaning and weed or graffiti abatement; potential ways of resource allocation ADU; permitting and land allocation; and homeless housing. It establishes a general process flow for this blockchain architecture, which involves: 1) the creation of blocks (transactions); 2) sending these blocks to nodes (users) on the network for an action (mining) and then validation that that action has taken place; and 3) …


Socio-Demographic And Trauma-Related Predictors Of Depression Within Eight Weeks Of Motor Vehicle Collision In The Aurora Study, Jutta Joormann, Samuel A Mclean, Francesca L Beaudoin, Xinming An, Jennifer S Stevens, Donglin Zeng, Thomas C Neylan, Gari Clifford, Sarah D Linnstaedt, Laura T Germine, Scott L Rauch, Paul I Musey, Phyllis L Hendry, Sophia Sheikh, Christopher W Jones, Brittany E Punches, Gregory Fermann, Lauren A Hudak, Kamran Mohiuddin, Vishnu Murty, Meghan E Mcgrath, John P Haran, Jose Pascual, Mark Seamon, David A Peak, Claire Pearson, Robert M Domeier, Paulina Sergot, Roland Merchant, Leon D Sanchez, Niels K Rathlev, William F Peacock, Steven E Bruce, Deanna Barch, Diego A Pizzagalli, Beatriz Luna, Steven E Harte, Irving Hwang, Sue Lee, Nancy Sampson, Karestan C Koenen, Kerry J Ressler, Ronald C Kessler Jul 2022

Socio-Demographic And Trauma-Related Predictors Of Depression Within Eight Weeks Of Motor Vehicle Collision In The Aurora Study, Jutta Joormann, Samuel A Mclean, Francesca L Beaudoin, Xinming An, Jennifer S Stevens, Donglin Zeng, Thomas C Neylan, Gari Clifford, Sarah D Linnstaedt, Laura T Germine, Scott L Rauch, Paul I Musey, Phyllis L Hendry, Sophia Sheikh, Christopher W Jones, Brittany E Punches, Gregory Fermann, Lauren A Hudak, Kamran Mohiuddin, Vishnu Murty, Meghan E Mcgrath, John P Haran, Jose Pascual, Mark Seamon, David A Peak, Claire Pearson, Robert M Domeier, Paulina Sergot, Roland Merchant, Leon D Sanchez, Niels K Rathlev, William F Peacock, Steven E Bruce, Deanna Barch, Diego A Pizzagalli, Beatriz Luna, Steven E Harte, Irving Hwang, Sue Lee, Nancy Sampson, Karestan C Koenen, Kerry J Ressler, Ronald C Kessler

Faculty, Staff and Students Publications

BACKGROUND: This is the first report on the association between trauma exposure and depression from the

METHODS: We focus on participants presenting at EDs after a motor vehicle collision (MVC), which characterizes most AURORA participants, and examine associations of participant socio-demographics and MVC characteristics with 8-week depression as mediated through peritraumatic symptoms and 2-week depression.

RESULTS: Eight-week depression prevalence was relatively high (27.8%) and associated with several MVC characteristics (being passenger

CONCLUSIONS: These observations, coupled with substantial variation in the relative strength of the mediating pathways across predictors, raises the possibility of diverse and potentially complex underlying biological and psychological …


“It Felt Like Having A Second Job”: Perspectives From Deaf Professionals On Communication Equity In The Workplace, Paul B. Harrelson, Brenda S. Nicodemus Jul 2022

“It Felt Like Having A Second Job”: Perspectives From Deaf Professionals On Communication Equity In The Workplace, Paul B. Harrelson, Brenda S. Nicodemus

JADARA

More than 50 years of nondiscrimination legislation in the United States has resulted in greater diversity in the workplace; however, questions persist about the communication equity of Deaf employees who use a signed language. In this study, we investigate systemic factors that underlie the provision of signed language interpreting services in the workplace. Using the Critical Incident Technique, observations were collected from 17 Deaf professionals regarding the systems of interpreter provision at work. The data resulted in four main findings: (1) Deaf professionals hold a sophisticated understanding of their communication needs, (2) both quality and quantity of interpreting are important, …


Influences On The Attachment Style Of Deaf Adults With Hearing Parents, Ellen Schaefer-Salins Jul 2022

Influences On The Attachment Style Of Deaf Adults With Hearing Parents, Ellen Schaefer-Salins

JADARA

The current study explored variables that could contribute to the development of a secure or insecure attachment style of 15 deaf adults between the ages of 30 and 50 with hearing parents. There is a paucity of information on the relationship of deaf adults to their hearing parent and how that relationship may influence attachment. For the current study, quantitative methods were used to explore both childhood and adulthood variables, such as type of communication used with parents, type and level of schooling, and current attachment style. Variables also studied include age, gender, race, birth order, marital status, the hearing …


A Novel, De Novo Intronic Variant In Pogz Causes White-Sutton Syndrome, Ashanta Merriweather, David R Murdock, Jill A Rosenfeld, Hongzheng Dai, Shamika Ketkar, Lisa Emrick, Sarah Nicholas, Richard A Lewis, Undiagnosed Diseases Network, Carlos A Bacino, Daryl A Scott, Brendan Lee, Vernon Reid Sutton, Lorraine Potocki, Lindsay C Burrage Jul 2022

A Novel, De Novo Intronic Variant In Pogz Causes White-Sutton Syndrome, Ashanta Merriweather, David R Murdock, Jill A Rosenfeld, Hongzheng Dai, Shamika Ketkar, Lisa Emrick, Sarah Nicholas, Richard A Lewis, Undiagnosed Diseases Network, Carlos A Bacino, Daryl A Scott, Brendan Lee, Vernon Reid Sutton, Lorraine Potocki, Lindsay C Burrage

Center for Medical Ethics and Health Policy Staff Publications

White-Sutton syndrome (WHSUS), which is caused by heterozygous pathogenic variants in POGZ, is characterized by a spectrum of intellectual disabilities and global developmental delay with or without features of autism spectrum disorder. Additional features may include hypotonia, behavioral abnormalities, ophthalmic abnormalities, hearing loss, sleep apnea, microcephaly, dysmorphic facial features, and rarely, congenital diaphragmatic hernia (CDH). We present a 6-year-old female with features of WHSUS, including CDH, but with nondiagnostic clinical trio exome sequencing. Exome sequencing reanalysis revealed a heterozygous, de novo, intronic variant in POGZ (NM_015100.3:c.2546-20T>A). RNA sequencing revealed that this intronic variant leads to skipping of exon 18. …


The Role Of An Inpatient Hospice And Palliative Clinical Pharmacist In The Interdisciplinary Team, Jetavia Jones Moody, Ivy O Poon, Ursula K Braun Jul 2022

The Role Of An Inpatient Hospice And Palliative Clinical Pharmacist In The Interdisciplinary Team, Jetavia Jones Moody, Ivy O Poon, Ursula K Braun

Center for Medical Ethics and Health Policy Staff Publications

Palliative care is a specialized health care service for individuals with serious illness at any stage and can be provided in any setting. Current national consensus developed by palliative care experts recommends the inclusion of pharmacists in an interdisciplinary team (IDT) to provide quality palliative care. However, national registry data report that less than 10% of inpatient palliative teams in the U.S. have a clinical pharmacist. Clinical pharmacists have an impactful role in palliative patients' quality of life by optimizing symptom management, deprescribing, and providing education to the palliative care team as well as patients and their families. In this …


Journalism As Historical Repair Work: Addressing Present Injustice Through The Second Draft Of History, Nik Usher, Matt Carlson Jul 2022

Journalism As Historical Repair Work: Addressing Present Injustice Through The Second Draft Of History, Nik Usher, Matt Carlson

Communication: Faculty Scholarship

As part of contemporary racial reckoning, institutions are acknowledging their historical legacies of racism and discrimination. Media institutions, given their role in the social construction of reality, have been called to account by racial justice activists for perpetuating the white-dominant status quo. We develop a framework for recognizing and interpreting efforts at historical repair work in journalism, second draft of history journalism (SDOH), whereby contemporary consciousness about racial injustice, structural inequality, and exclusionary practices inside and outside journalism prompt news organizations to revisit the historical record. Through case study exemplars at U.S. newspapers, we define the three main modes—active, reflective, …


Reconsidering The “Acculturation Gap”: Mother-Adolescent Cultural Adaptation Mis/Matches And Positive Psychosocial Outcomes Among Mexican-Origin Families, Jinjin Yan, Lester Sim, Jiaxiu Song, Shanting Chen, Su Yeong Kim Jul 2022

Reconsidering The “Acculturation Gap”: Mother-Adolescent Cultural Adaptation Mis/Matches And Positive Psychosocial Outcomes Among Mexican-Origin Families, Jinjin Yan, Lester Sim, Jiaxiu Song, Shanting Chen, Su Yeong Kim

Research Collection School of Social Sciences

Previous studies have linked parent-child cultural adaptation mismatches with adolescents’ maladjustment without addressing how intergenerational mis/matches are related to positive aspects of adolescent development and parental outcomes. Using data from 604 Mexican-origin families (adolescent sample:54%female, Mage = 12.41, range = 11 to 15), response surface analysis was conducted to investigate how mother-child mis/matches in cultural adaptation (acculturation, enculturation, English and Spanish proficiency) are associated with adolescents’ and mothers’ resilience and life meaning. Adolescents and mothers reported greater resilience and meaning when they matched at higher, versus lower, levels of acculturation, enculturation and English proficiency; adolescents reported more resilience when they …