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Full-Text Articles in Social and Behavioral Sciences

Review: Digital Memory Studies: Media Pasts In Transition, Donnie S. Summerlin Oct 2022

Review: Digital Memory Studies: Media Pasts In Transition, Donnie S. Summerlin

Provenance, Journal of the Society of Georgia Archivists

Book review of Digital Memory Studies: Media Pasts in Transition. Edited by Andrew Hoskins (New York: Routledge, 2018. 313 pp.). Review by Donnie Summerlin.


Georgia Southern’S Checkout Equipment: Laptops, Cameras, Boardgames, And More. How We Manage The Checkout Equipment Program, Wilhelmina Randtke, Lonnie Brogdon, Tony Curtis, Jessica Garner Oct 2022

Georgia Southern’S Checkout Equipment: Laptops, Cameras, Boardgames, And More. How We Manage The Checkout Equipment Program, Wilhelmina Randtke, Lonnie Brogdon, Tony Curtis, Jessica Garner

University Libraries: Faculty Presentations

Presentation given at the Georgia Libraries Conference, Macon, GA.

Georgia Southern makes available a variety of equipment for student check out including a fleet of approximately 200 laptops, high-end digital cameras, tripods and lighting kits, video recording equipment, high-end microphones, and more. Equipment checkout is popular with students with equipment cycling in and out. Equipment also presents unique cataloging challenges. MARC was designed for books, and providing a good search for pulling statistics for non-traditional items can be a challenge. Items also may be returned needing repairs and Georgia Southern performs in-house repairs on laptops and other electronics. Participants will …


Protecting Against Adversity: The Role Of Positive Childhood Experiences In Youth Recidivism, Melissa Kowalski, Zachary Hamilton, Alex Kigerl, Michael T. Baglivio, Kevin T. Wolff Oct 2022

Protecting Against Adversity: The Role Of Positive Childhood Experiences In Youth Recidivism, Melissa Kowalski, Zachary Hamilton, Alex Kigerl, Michael T. Baglivio, Kevin T. Wolff

Criminology and Criminal Justice Faculty Publications

An abundance of research has established Adverse Childhood Experiences’ (ACEs’) contributions to deviant behavior. Recently, studies have demonstrated the importance of Positive Childhood Experiences (PCEs). Yet, the PCE establishment as a predictive scale is needed. In a multistate, robust sample (N = 254,874) of justice-involved youth, we examined PCE scale effects and ACE-PCE combinations on recidivism using mixed effects logistic regression while adjusting for the impact of state. Presence of PCEs was associated with lower reoffending likelihood, and ACEs were related to increased recidivism odds. Further, PCEs demonstrated a protective impact on ACEs. A ceiling effect on the ACE-PCE composite …


How Hearing Parents With Deaf Or Hard Of Hearing Children Construct Deafness Through Their Early Intervention Experience, Bettie T. Petersen Oct 2022

How Hearing Parents With Deaf Or Hard Of Hearing Children Construct Deafness Through Their Early Intervention Experience, Bettie T. Petersen

Language, Literacy, and Sociocultural Studies ETDs

This dissertation explores how hearing parents with deaf/hard of hearing children come to understand deafness. This mixed methods study used an online survey and multiple case studies (volunteers from survey). Participants were asked about early intervention experiences and beliefs about deafness. The survey had 74 respondents and five families participated in the interviews. Survey participants’ beliefs about deafness were primarily medical, focusing on the perceived barriers caused by deafness and the remediation of those barriers through spoken language options. A small number of respondents adopted a cultural perspective of deafness and focused on remediation of barriers through involvement in the …


Ethical Hiv Research With Transgender And Non-Binary Communities In The United States, Augustus Klien, Sarit Golub Oct 2022

Ethical Hiv Research With Transgender And Non-Binary Communities In The United States, Augustus Klien, Sarit Golub

Publications and Research

Introduction: Because transgender individuals experience disproportionately high rates of HIV infection, this population is an increasing focus of epidemiological and implementation science research to combat the epidemic. However, study participants, providers and other advocates have become increasingly concerned about research practices that may alienate, objectify, exploit or even re-traumatize the communities they are designed to benefit. This commentary explores the common pitfalls of HIV research with transgender communities and provides a potential framework for ethical, community-engaged research practice.

Discussion: We review some of the critical challenges to HIV research with transgender and non-binary communities that limit the potential for such …


Mindfulness-Based Interventions For Survivors Of Lung Cancer And Their Partners: A Systematic Review, Karen Kane Mcdonnell, Otis L. Owens, Fattona Umari Oct 2022

Mindfulness-Based Interventions For Survivors Of Lung Cancer And Their Partners: A Systematic Review, Karen Kane Mcdonnell, Otis L. Owens, Fattona Umari

Faculty Publications

Background

Survivors of lung cancer and their partners often have complex unresolved physical, psychosocial, and behavioral needs that can negatively affect the survivors’ and partners’ well-being. This systematic review aimed to (1) examine the content and delivery of mindfulness-based interventions (MBIs) and (2) summarize and synthesize the current evidence for effectiveness of MBIs targeting survivors of lung cancer and/or one selected partner (dyads).

Method

Six databases were searched for interventional studies published in English between 1980 and June 2020 using three terms (lung neoplasms, mindfulness, caregivers). For outcome measures, the interventions focused on behavioral change (meditation, yoga, stretching, breathing), symptom …


Sports Coaches’ Depression Literacy, And Engagement In Prevention And Early Intervention Behaviors: A Moderated Mediation Analysis, Cliona O’Leary, Brendan Rooney, Bradley Donohue, James Matthews Oct 2022

Sports Coaches’ Depression Literacy, And Engagement In Prevention And Early Intervention Behaviors: A Moderated Mediation Analysis, Cliona O’Leary, Brendan Rooney, Bradley Donohue, James Matthews

Psychology Faculty Research

Coaches’ mental health literacy is associated with increased engagement in prevention and early intervention behaviors. However, few studies have explored the factors that may influence these relationships. The purpose of this study was to explore whether role breadth and role efficacy mediate the relationship between coach depression literacy and prevention and early intervention, and to assess whether gender or stigma moderates any mediation effects. One thousand and forty five coaches (M ¼ 42.71 years old; SD¼ 11.52; 30% female) completed an online survey exploring depression literacy, personal stigma, role breadth and efficacy and engagement in prevention and early intervention. Path …


Collaborative Constructions: Designing High School History Curriculum With The Lost & Found Game Series, Owen Gottlieb, Shawn Clybor Oct 2022

Collaborative Constructions: Designing High School History Curriculum With The Lost & Found Game Series, Owen Gottlieb, Shawn Clybor

Articles

This chapter addresses design research and iterative curriculum design for the Lost & Found games series. The Lost & Found card-to-mobile series is set in Fustat (Old Cairo) in the twelfth century and focuses on religious laws of the period. The first two games focus on Moses Maimonides’ Mishneh Torah, a key Jewish law code. A new expansion module which was in development at the time of the fieldwork described in this article that introduces Islamic laws of the period, and a mobile prototype of the initial strategy game has been developed with support National Endowment for the Humanities. The …


Lindenwood Digest, October 12, 2022, Lindenwood University Oct 2022

Lindenwood Digest, October 12, 2022, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.


Understanding Self-Compassion Within Narrative Identity: The Struggles Of Japanese Students With Measuring Up, Anton Sevilla-Liu Oct 2022

Understanding Self-Compassion Within Narrative Identity: The Struggles Of Japanese Students With Measuring Up, Anton Sevilla-Liu

The Qualitative Report

The psychology of self-compassion is growing in importance for understanding well-being and helping people in therapeutic and educational settings. However, present research may be limited by a narrow focus on nomothetic self-reports like the Self-Compassion Scale. This article supplements that qualitatively, looking at self-compassion in life stories. It is guided by the questions, “How do students experience the struggle between self-compassion and its deficit? And how is this experience manifest in their narrative identity?” This study examined three Japanese university students who submitted their narrative self-reflections, including stories of the high point, low point, turning point, and recurring pattern in …


Measurement Of Severe Acute Respiratory Syndrome Coronavirus 2 Antigens In Plasma Of Pediatric Patients With Acute Coronavirus Disease 2019 Or Multisystem Inflammatory Syndrome In Children Using An Ultrasensitive And Quantitative Immunoassay, George B Sigal, Tanya Novak, Anu Mathew, Janet Chou, Yubo Zhang, Navaratnam Manjula, Pradeepthi Bathala, Jessica Joe, Nikhil Padmanabhan, Daniel Romero, Gabriella Allegri-Machado, Jill Joerger, Laura L Loftis, Stephanie P Schwartz, Tracie C Walker, Julie C Fitzgerald, Keiko M Tarquinio, Matt S Zinter, Jennifer E Schuster, Natasha B Halasa, Melissa L Cullimore, Aline B Maddux, Mary A Staat, Katherine Irby, Heidi R Flori, Bria M Coates, Hillary Crandall, Shira J Gertz, Adrienne G Randolph, Nira R Pollock, Overcoming Covid-19 Investigators Oct 2022

Measurement Of Severe Acute Respiratory Syndrome Coronavirus 2 Antigens In Plasma Of Pediatric Patients With Acute Coronavirus Disease 2019 Or Multisystem Inflammatory Syndrome In Children Using An Ultrasensitive And Quantitative Immunoassay, George B Sigal, Tanya Novak, Anu Mathew, Janet Chou, Yubo Zhang, Navaratnam Manjula, Pradeepthi Bathala, Jessica Joe, Nikhil Padmanabhan, Daniel Romero, Gabriella Allegri-Machado, Jill Joerger, Laura L Loftis, Stephanie P Schwartz, Tracie C Walker, Julie C Fitzgerald, Keiko M Tarquinio, Matt S Zinter, Jennifer E Schuster, Natasha B Halasa, Melissa L Cullimore, Aline B Maddux, Mary A Staat, Katherine Irby, Heidi R Flori, Bria M Coates, Hillary Crandall, Shira J Gertz, Adrienne G Randolph, Nira R Pollock, Overcoming Covid-19 Investigators

Center for Medical Ethics and Health Policy Staff Publications

Background: Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens in blood has high sensitivity in adults with acute coronavirus disease 2019 (COVID-19), but sensitivity in pediatric patients is unclear. Recent data suggest that persistent SARS-CoV-2 spike antigenemia may contribute to multisystem inflammatory syndrome in children (MIS-C). We quantified SARS-CoV-2 nucleocapsid (N) and spike (S) antigens in blood of pediatric patients with either acute COVID-19 or MIS-C using ultrasensitive immunoassays (Meso Scale Discovery).

Methods: Plasma was collected from inpatients (< 21 years) enrolled across 15 hospitals in 15 US states. Acute COVID-19 patients (n = 36) had a range of disease severity and positive nasopharyngeal SARS-CoV-2 RT-PCR within 24 hours of blood collection. Patients with MIS-C (n = 53) met CDC criteria and tested positive for SARS-CoV-2 (RT-PCR or serology). Controls were patients pre-COVID-19 (n = 67) or within 24 hours of negative RT-PCR (n = 43).

Results: Specificities of N and S assays were 95-97% and 100%, respectively. In acute COVID-19 patients, N/S plasma assays …


Screen Time Among Children With Mental, Emotional, Developmental, Or Behavioral Problems (Medb) - A Us Population-Based Study, Saral R. Desai, Amanda Shapiro Oct 2022

Screen Time Among Children With Mental, Emotional, Developmental, Or Behavioral Problems (Medb) - A Us Population-Based Study, Saral R. Desai, Amanda Shapiro

Tower Health Research Day

No abstract provided.


The Impact Of Facial Feminization On Qol In Transgender Patients, Odette Rosales, Zane Sejdiu, Justin Michael Camacho, Ali Yasback, Caroline E. Quindlen, Sanjeev Herr, Amir Behnam Md Oct 2022

The Impact Of Facial Feminization On Qol In Transgender Patients, Odette Rosales, Zane Sejdiu, Justin Michael Camacho, Ali Yasback, Caroline E. Quindlen, Sanjeev Herr, Amir Behnam Md

Tower Health Research Day

No abstract provided.


Review Of Making Your Tools Work For You: Building And Maintaining An Integrated Technical Ecosystem For Digital Archives And Libraries, Lindsey Memory Oct 2022

Review Of Making Your Tools Work For You: Building And Maintaining An Integrated Technical Ecosystem For Digital Archives And Libraries, Lindsey Memory

Journal of Western Archives

Review of Making Your Tools Work for You: Building and Maintaining an Integrated Technical Ecosystem for Digital Archives and Libraries.


Spartan Daily, October 11, 2022, San Jose State University, School Of Journalism And Mass Communications Oct 2022

Spartan Daily, October 11, 2022, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2022

Volume 159, Issue 21


Analyzing Discoverability In An Mplp World: How Levels Of Description Impact Findability, Anna-Maria Arnljots, Paul Daybell, Kurt Alan Meyer, Andrea Payant, Becky Skeen, Liz Woolcott Oct 2022

Analyzing Discoverability In An Mplp World: How Levels Of Description Impact Findability, Anna-Maria Arnljots, Paul Daybell, Kurt Alan Meyer, Andrea Payant, Becky Skeen, Liz Woolcott

Library Faculty & Staff Presentations

Libraries and archives have differing opinions on how much effort to put into content description. Yet, descriptive practices meant to reduce processing time and increase exposure to collections can have unintended impacts on long-term user discovery. This project tests minimal and full description to determine the effects on discoverability.


Ms 242 Guide To The John Z. Bowers, Md Papers (1947-1983), John Z. Bowers (1913-1993) Oct 2022

Ms 242 Guide To The John Z. Bowers, Md Papers (1947-1983), John Z. Bowers (1913-1993)

Manuscript Finding Aids

This collection includes photographs, manuscripts, and reprints related to Dr. John Bowers' involvement with the Atomic Bomb Casualty Commission (ABCC). Of particular note are 58 black-and-white photographs of Nagasaki, Japan, taken by Captain Shields Warren (MC) in 1947. There is also a photograph showing Dr. Bowers alongside Carl Tessmer reviewing plans for the ABCC laboratory-clinic in Hiroshima, and another featuring the groundbreaking of the Radiation Effects Research Foundation (RERF). A third set of photographs depicts Berlin, Germany during the Cold War. See more at MS 242.


Ms 241 Guide To The Thomas D. Dow, Dds Papers (1884-1944), Thomas D. Dow (1876-1960) Oct 2022

Ms 241 Guide To The Thomas D. Dow, Dds Papers (1884-1944), Thomas D. Dow (1876-1960)

Manuscript Finding Aids

This collection contains materials related to Thomas D. Dow's collecting of books and journals on dentistry. Correspondence and book lists make up the bulk of the materials, which date from 1884-1944. See more at MS 241.


Ms 243 Guide To The Louise Cavagnaro Papers (1948-1992), Louise Cavagnaro (1920-2010) Oct 2022

Ms 243 Guide To The Louise Cavagnaro Papers (1948-1992), Louise Cavagnaro (1920-2010)

Manuscript Finding Aids

This collection consists of photographs, clippings, publications, a thesis review, and correspondence relating to the Atomic Bomb Casualty Commission (ABCC). Most of the materials date from 1948 to 1962, although some items are undated. Cavagnaro's review of "War Guilt and Medical Research" is from 1992. Collection materials generally originated in Japan or discuss conditions there. See more at MS 243.


Person, (Place,) Or Thing: Centering People With Caring Language And The Acknowledgement Of Performance, Kiley Jolicoeur Oct 2022

Person, (Place,) Or Thing: Centering People With Caring Language And The Acknowledgement Of Performance, Kiley Jolicoeur

Librarian Publications

This presentation details remediation work done on harmful legacy metadata as part of the Syracuse University Libraries digital collections migration of the Sideshow Performers Collection, which contains digitized images from the Ronald G. Becker Collection of Charles Eisenmann photographs. The discussion focuses on deconstructing the legacy information and reconstructing it in ways that center the individual performer depicted, rather than portraying them as a medicalized specimen.

No session recording is available, but presenter's notes are included on the slides.


Older Immigrants Are More Likely Than Older Nonimmigrants To Experience Loneliness, Stephanie Zemba, Janet Wilmoth Oct 2022

Older Immigrants Are More Likely Than Older Nonimmigrants To Experience Loneliness, Stephanie Zemba, Janet Wilmoth

Population Health Research Brief Series

Loneliness in older adults is a growing U.S. population health problem, especially among immigrants This research brief explores the impact of age at immigration on loneliness and considers factors such as health, socio-demographic characteristics, and engagement in volunteering on loneliness. Findings demonstrate the need for programs that promote social connection among older adult immigrants to combat feelings of loneliness.


Ms 181 Guide To The Leta Denham, Rn Papers (1918-1920), Leta Elizabeth Denham (1895-1982) Oct 2022

Ms 181 Guide To The Leta Denham, Rn Papers (1918-1920), Leta Elizabeth Denham (1895-1982)

Manuscript Finding Aids

The Leta Denham, RN papers contains a short handwritten family history, scrapbook segments, photographs, a school yearbook from 1918, newspaper clippings, a nursing cap, and other items related to Leta Elizabeth Denham's nursing education at Baptist Sanitarium and Hospital Training School for Nurses from 1918 to 1919. See more at MS 181.


Personality And Psychopathology Correlates Of Institutional Misconduct Among Juvenile Offenders, Paula Floyd Oct 2022

Personality And Psychopathology Correlates Of Institutional Misconduct Among Juvenile Offenders, Paula Floyd

Dissertations

Juvenile delinquency is a national concern, as delinquent behavior is associated with a host of poor psychosocial outcomes during later adolescence and adulthood. To address delinquency, it is important to understand psychological adjustment among adolescents who have already made contact with the juvenile justice system. One way to explore adjustment within this population involves examining personality and psychopathology correlates of institutional misconduct (i.e., behavioral infractions while incarcerated). While there is a robust body of literature regarding personality and psychopathology correlates of misconduct in adult inmate samples, there has been far less work devoted to these relationships among justice-involved youth. Furthermore, …


Grounding Systemic Functional Linguistics And Critical Theory In Deepening Ell's Discipline Knowledge And Exploring The Praxis Of Teaching And Researching Disciplinary Literacy Development: A Book Review, Elih Sutisna Yanto, Junjun Muhamad Ramdani Oct 2022

Grounding Systemic Functional Linguistics And Critical Theory In Deepening Ell's Discipline Knowledge And Exploring The Praxis Of Teaching And Researching Disciplinary Literacy Development: A Book Review, Elih Sutisna Yanto, Junjun Muhamad Ramdani

The Qualitative Report

In the book, Teaching and Researching ELLs’ Disciplinary Literacies: SFL in Action in the Context of US School Reform (2019), Meg Gebhard, professor of Applied Linguistics and co-director of the Secondary English Education Program at the University of Massachusetts, Amherst, USA, provides a comprehensive description to second language researchers, multilingual learners, language teachers, and teacher educators of how Halliday's Systemic Functional Linguistics (SFL) can be applied to give ELLs access to the language and literacies they need to succeed across the curriculum. Throughout the chapters, Gebhard provides convincing evidence that mastering their various grammars and genres (text types) is equally …


Analysis Of Hybrid Learning For Students With Learning Disabilities In Primary Schools Providing Inclusive Education, Nugraheni Rachmawati, Asep Supena, Yufiarti Yufiarti, Gusti Yarmi, Asep Rudi Casmana Oct 2022

Analysis Of Hybrid Learning For Students With Learning Disabilities In Primary Schools Providing Inclusive Education, Nugraheni Rachmawati, Asep Supena, Yufiarti Yufiarti, Gusti Yarmi, Asep Rudi Casmana

The Qualitative Report

Many special-needs children, including students with learning disabilities, are enrolled in public schools. The current state of education is transitioning from online to face-to-face learning due to the improving situation after the COVID-19 pandemic. Hybrid learning is one of the alternative methods applied during the transition period. Therefore, this study aims to explore the experiences of teachers in implementing hybrid learning in students with disabilities in Indonesia using a qualitative description. Data was collected through interviews with one class teacher, two students with learning disabilities and their parents, and one school principal. Furthermore, observations were made on the learning process …


A Snapshot Of Science Education During Covid-19 In The Spring Of 2021, Lily Bentley Oct 2022

A Snapshot Of Science Education During Covid-19 In The Spring Of 2021, Lily Bentley

The Qualitative Report

The COVID-19 pandemic has placed many unique challenges on our education system. Unpacking the many issues that educators faced will allow researchers to understand some of the impacts that resulted from this unique phenomenon. This exploratory qualitative research study sought to understand how science educators and administrators made sense of science instruction during the spring of 2021. Data was collected through semi-structured interviews and online observations with ten K-12 science teachers and four administrators across two different counties within Virginia. Thematic coding was employed to analyze the findings, and results were validated through member checking with participants. Participants shared that …


Cue-Induced Cocaine Craving Enhances Psychosocial Stress And Vice Versa In Chronic Cocaine Users, Ann-Kathrin Kexel, Bruno Kluwe-Schiavon, Markus R Baumgartner, Etna J E Engeli, Monika Visentini, Clemens Kirschbaum, Erich Seifritz, Beate Ditzen, Leila M Soravia, Boris B Quednow Oct 2022

Cue-Induced Cocaine Craving Enhances Psychosocial Stress And Vice Versa In Chronic Cocaine Users, Ann-Kathrin Kexel, Bruno Kluwe-Schiavon, Markus R Baumgartner, Etna J E Engeli, Monika Visentini, Clemens Kirschbaum, Erich Seifritz, Beate Ditzen, Leila M Soravia, Boris B Quednow

Faculty, Staff and Student Publications

Stress and craving, it has been found, contribute to the development and maintenance of and relapse in cocaine use disorder. Chronic cocaine users (CU), previous research has shown, display altered physiological responses to psychosocial stress and increased vegetative responding to substance-related cues. However, how psychosocial stress and cue-induced craving interact in relation to the CU's physiological responses remains largely unknown. We thus investigated the interaction between acute psychosocial stress and cocaine-cue-related reactivity in 47 CU and 38 controls. In a crossed and balanced design, the participants were randomly exposed to a video-based cocaine-cue paradigm and the Trier Social Stress Test …


Evaluation Of Safe Firearm Storage Messaging In A Sample Of Firearm-Owning Us Military Service Members., Michael D. Anestis, Craig J. Bryan, Daniel W. Capron Oct 2022

Evaluation Of Safe Firearm Storage Messaging In A Sample Of Firearm-Owning Us Military Service Members., Michael D. Anestis, Craig J. Bryan, Daniel W. Capron

Faculty Publications

Importance Nearly two-thirds of military suicides involve firearms, and safe firearm storage is rare.

Objective To examine whether US military service members endorse greater openness to safe firearm storage depending on the content of the visual message they are randomly assigned to view.

Design, Setting, and Participants This comparative effectiveness study used a 3 × 2 × 2 factorial design to randomize US military service members to view 1 of 12 visual messages on safe firearm storage. Willingness to use safe firearm storage practices was assessed immediately before and after exposure to the message. Participants were recruited using the KnowledgePanel …


User Perception Of The Effectiveness Of Open Access Resources In Academic And Professional Achievements, Eness Munzya Miyanda-Chitumbo Dr., Thomas Van Der Walt Prof., Magdalene Simalalo Dr., Pailet Chewe Mr., Zachary Zulu Mr., Inonge Milupi Dr., Mercy Monde Wamunyima Mrs. Oct 2022

User Perception Of The Effectiveness Of Open Access Resources In Academic And Professional Achievements, Eness Munzya Miyanda-Chitumbo Dr., Thomas Van Der Walt Prof., Magdalene Simalalo Dr., Pailet Chewe Mr., Zachary Zulu Mr., Inonge Milupi Dr., Mercy Monde Wamunyima Mrs.

Library Philosophy and Practice (e-journal)

Abstract.

This study examined the University of Zambia students and researchers’ perception of the relevance of open access resources in their academic and professional work.The investigation was based on continued problem of low usage of online resources provided by the University of Zambia Library to support learning, teaching and research in the University. The study used a mixed-methods approach and took a case study-mixed methods design to investigate the research problem.

Findings:The study revealed that although the overall results showed an average level of awareness and low usage of the open access resources among students and researchers, …


Maternal Gut Microbiota Mediate Intergenerational Effects Of High-Fat Diet On Descendant Social Behavior, Claudia M Di Gesù, Lisa M Matz, Ian J Bolding, Robert Fultz, Kristi L Hoffman, Antonella Marino Gammazza, Joseph F Petrosino, Shelly A Buffington Oct 2022

Maternal Gut Microbiota Mediate Intergenerational Effects Of High-Fat Diet On Descendant Social Behavior, Claudia M Di Gesù, Lisa M Matz, Ian J Bolding, Robert Fultz, Kristi L Hoffman, Antonella Marino Gammazza, Joseph F Petrosino, Shelly A Buffington

Faculty, Staff and Students Publications

Dysbiosis of the maternal gut microbiome during pregnancy is associated with adverse neurodevelopmental outcomes. We previously showed that maternal high-fat diet (MHFD) in mice induces gut dysbiosis, social dysfunction, and underlying synaptic plasticity deficits in male offspring (F1). Here, we reason that, if HFD-mediated changes in maternal gut microbiota drive offspring social deficits, then MHFD-induced dysbiosis in F1 female MHFD offspring would likewise impair F2 social behavior. Metataxonomic sequencing reveals reduced microbial richness among female F1 MHFD offspring. Despite recovery of microbial richness among MHFD-descendant F2 mice, they display social dysfunction. Post-weaning Limosilactobacillus reuteri treatment increases the abundance of short-chain …