Open Access. Powered by Scholars. Published by Universities.®
Social and Behavioral Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Anthropology (115980)
- Arts and Humanities (114009)
- Archaeological Anthropology (96468)
- Communication (89177)
- Sociology (86996)
-
- Library and Information Science (79658)
- Psychology (73717)
- Education (63236)
- Public Affairs, Public Policy and Public Administration (62984)
- History (49317)
- Economics (47013)
- Political Science (41881)
- Journalism Studies (41442)
- Mass Communication (35097)
- Medicine and Health Sciences (33668)
- Business (31776)
- Law (29755)
- International and Area Studies (29034)
- Religion (26371)
- Life Sciences (22951)
- Physical Sciences and Mathematics (21175)
- United States History (21111)
- Disability Studies (18907)
- Archival Science (18703)
- Catholic Studies (17680)
- Social History (17364)
- Social Work (16386)
- Higher Education (15766)
- Legal Studies (15129)
- Institution
-
- Kenyon College (90122)
- San Jose State University (23479)
- College of the Holy Cross (18332)
- Western Kentucky University (17443)
- University of Nebraska - Lincoln (16702)
-
- Purdue University (11626)
- University of Central Florida (11266)
- Portland State University (10476)
- Hope College (10070)
- Singapore Management University (9289)
- City University of New York (CUNY) (9088)
- Western Michigan University (8806)
- University of Kentucky (8788)
- Brigham Young University (8231)
- University of Nebraska at Omaha (7433)
- Chulalongkorn University (7224)
- Nova Southeastern University (6947)
- Grand Valley State University (6655)
- Northwestern Pritzker School of Law (6515)
- Ursinus College (6412)
- Walden University (6380)
- Kennesaw State University (5836)
- Wright State University (5801)
- Old Dominion University (5749)
- Utah State University (5493)
- University of Nevada, Las Vegas (5403)
- James Madison University (4916)
- University of Massachusetts Boston (4574)
- Syracuse University (4384)
- University of Northern Iowa (4353)
- Keyword
-
- Newspaper (24534)
- Deaf culture (17047)
- Hearing impaired (17047)
- Pastoral care of people with disabilities (17039)
- Church work with the deaf -- Catholic Church (17031)
-
- Deaf -- Periodicals (17022)
- Spartan Daily (12401)
- Western Kentucky University (8598)
- Newspapers (8443)
- Michigan (6700)
- Holland (5964)
- Local newspapers (5902)
- Pennsylvania (5690)
- Holland City News (5484)
- Collegeville (5414)
- Montgomery County (5354)
- Trappe (5309)
- Student newspaper (4571)
- Norristown (4312)
- Education (4237)
- Communication (4229)
- Student Newspaper (4023)
- Law libraries (3904)
- Law librarians (3817)
- SEAALL (3767)
- Student newspapers (3602)
- Kentucky (3552)
- Wright State University (3397)
- Gender (3370)
- Archaeology (3211)
- Publication Year
-
- 2026 (12744)
- 2025 (19474)
- 2024 (20651)
- 2023 (20699)
- 2022 (22564)
-
- 2021 (24088)
- 2020 (23488)
- 2019 (26090)
- 2018 (22831)
- 2017 (21434)
- 2016 (21480)
- 2015 (19696)
- 2014 (18483)
- 2013 (17400)
- 2012 (15703)
- 2011 (13782)
- 2010 (12751)
- 2009 (11930)
- 2008 (11622)
- 2007 (8953)
- 2006 (8226)
- 2005 (9032)
- 2004 (13903)
- 2002 (14539)
- 2000 (12380)
- 1996 (24086)
- 1995 (13620)
- 1992 (12546)
- 1990 (17675)
- 1988 (10228)
- Publication
-
- Four Valleys Archive (90076)
- Spartan Daily (School of Journalism and Mass Communications) (11410)
- Theses and Dissertations (8859)
- WKU Administration Documents (7431)
- Library Philosophy and Practice (e-journal) (7221)
-
- Against the Grain (6901)
- Journal of Criminal Law and Criminology (6417)
- Walden Dissertations and Doctoral Studies (5913)
- Electronic Theses and Dissertations (5494)
- Dissertations (5199)
- Faculty Publications (4632)
- Masters Theses (4045)
- Publications and Research (3309)
- The Journal of Sociology & Social Welfare (3255)
- Master's Theses (3064)
- Dissertations and Theses (3031)
- Honors Theses (3003)
- The Qualitative Report (3000)
- Independent Study Project (ISP) Collection (2931)
- Cowles Foundation Discussion Papers (2930)
- The Independent Newspaper, 1898-1952 (2730)
- Dissertations, Theses, and Capstone Projects (2711)
- The Guardian Student Newspaper (2691)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (2614)
- Doctoral Dissertations and Projects (2604)
- Great Plains Quarterly (through 2013) (2472)
- Correspondence (2468)
- Central Florida Future (2281)
- USF Tampa Graduate Theses and Dissertations (2273)
- Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State (2263)
- Publication Type
Articles 75901 - 75930 of 658862
Full-Text Articles in Social and Behavioral Sciences
Typical Pathway To Carbon Neutrality For Urban Smart Energy Systems—Case Study Of Macao Special Administrative Region, Yonghua Song, Hongcai Zhang, Ge Chen
Typical Pathway To Carbon Neutrality For Urban Smart Energy Systems—Case Study Of Macao Special Administrative Region, Yonghua Song, Hongcai Zhang, Ge Chen
Bulletin of Chinese Academy of Sciences (Chinese Version)
China's ambitious goal "strive to peak carbon emissions before 2030 and achieve carbon neutrality before 2060" not only shows China's responsible attitude towards climate change, but also aligns with the upgrade requirement of China's economy and industries. Since cities occupy a dominant position in China's population, energy consumption, and carbon emissions, they are the main battlefield for achieving national carbon neutrality. This study first analyzes the challenges and requirements that cities' energy systems facing in order to realize carbon neutrality. Then, it takes Macao as an example to analyze the characteristics of cities' energy consumption and carbon emissions. Finally, it …
Policy Overview (October, 2022)
Policy Overview (October, 2022)
Bulletin of Chinese Academy of Sciences (Chinese Version)
No abstract provided.
Trend Observation: Research Development Trend And Enlightenment Of Superconducting Quantum Interference Device
Bulletin of Chinese Academy of Sciences (Chinese Version)
No abstract provided.
Digitization Of Information Resources In University Libraries In Nigeria: Challenges And Way Forward, Peter Olubunmi Olubiyo, Nancy E. Achebe (Prof.), Lydia M. Olubiyo
Digitization Of Information Resources In University Libraries In Nigeria: Challenges And Way Forward, Peter Olubunmi Olubiyo, Nancy E. Achebe (Prof.), Lydia M. Olubiyo
Library Philosophy and Practice (e-journal)
Libraries, archives, museums, and other memory institutions digitize items to preserve fragile materials and create more access points for patrons. The traditional role of the library as simply a place of storage and preservation of books and other information materials which has changed overwhelmingly since the advent of information and communication technologies (ICTs) Academic libraries are duly bound to acquire, preserve and disseminate information from whatever source, hence there is the need for such sources of information to be kept preserved and made available in a more convenient and accessible format. This calls for digitization which is the process of …
Masculinities And Affective Equality; The Case Of Professional Caring, Niall Hanlon
Masculinities And Affective Equality; The Case Of Professional Caring, Niall Hanlon
Articles
Critical studies of men and masculinities [CSMM] aim to advance gender equality by critiquing and deconstructing male hegemony and hegemonic masculinities. Although the implicit value of gender equality is clear in CSMM generally, the conceptualization of equality is frequently vague, implied, and lacks conceptual definition. The problem is compounded in caring masculinities studies which additionally often lack engagement with critical feminist and other socio-political perspectives on caring. These shortcomings hide the complex interrelation of different dimensions to inequality as they intersect with multiple relational identities. Caring practices are also complex having distinct phases that engage different forms of labour within …
Effect Of Covid-19 Pandemic On Volunteerism And Fundraising Management Strategies In Nonprofits And Rebuilding Tactics Of Ronald Mcdonald House Charities Of Chicagoland And Northwest Indiana (Rmhc-Cni), Humza Wolf
Nonprofit and NGO Studies Student Projects
The financial sustainability of nonprofits depends highly on volunteerism and funding strategies which got impacted during Coronavirus 2019 (COVID-19) Pandemic. This capstone study explores to what extent nonprofits got affected and evaluates the efforts of Ronald McDonald House Charities of Chicagoland & Northwest Indiana (RMHC-CNI) to improve the provision of support for underprivileged families of critically ill children. The continual efforts to overcome financial hurdles escalated in pandemic. Mixed method research design was used to collect, analyze, and triangulate both quantitative and qualitative research methods in this single study to understand the research problem. Interpretive approach encompassed the complexities of …
An Ethnography Of Voodoo Tourism And Heritage Sites In New Orleans, Lousiana, Bryant Long
An Ethnography Of Voodoo Tourism And Heritage Sites In New Orleans, Lousiana, Bryant Long
Master of Arts in Art and Design Theses
This thesis considers how Voodoo is presented and experienced in various tourism and heritage sites within New Orleans in the present moment. A variety of visual representations, verbal narratives and multimedia performances were documented and analyzed through participant observation. Current tourism relies on the city’s ghost stories, mythology, as well as Voodoo practices and lore, raising questions about the melding of fact and fiction in the potential perpetuation of sensational ideas about the city and its African heritage. Cultural sites discussed in this thesis include Congo Square, the New Orleans Voodoo Museum, Voodoo Authentica, the New Orleans Museum of Art, …
Framework Of Sns Usage For Knowledge And Information Sharing In Higher Learning Institutions In Tanzania, Jaffar Msafiri Ponera
Framework Of Sns Usage For Knowledge And Information Sharing In Higher Learning Institutions In Tanzania, Jaffar Msafiri Ponera
Library Philosophy and Practice (e-journal)
This study investigated a framework for implementing SNS for knowledge sharing in Tanzania's higher learning institutions (HLIs). The study deployed mixed-methods research, where a convergent research design was used. This enabled the researcher to collect quantitative and qualitative data in a similar research phase, but they were analysed differently. A convergent research design enabled the researcher to compare the findings obtained from quantitative data with those from qualitative data to ensure rigour. A total of 171 out of 239 targeted postgraduate students completed an online survey from the four HLIs in Kilimanjaro and Arusha regions, Tanzania. The study included eight …
How Things Take Up Space: A Grounded Theory Of Presence And Lived Space, Aleš Oblak, Asena Boyadzhieva, Jaya Caporusso, Borut Škodlar, Jurij Bon
How Things Take Up Space: A Grounded Theory Of Presence And Lived Space, Aleš Oblak, Asena Boyadzhieva, Jaya Caporusso, Borut Škodlar, Jurij Bon
The Qualitative Report
In cognitive science, it is unclear what precisely presence (both in the sense of objecthood and immersion) refers to in lived experience. The present study addresses the research question of what the relationship between presence is and lived space. A hundred and seventeen phenomenological interviews were conducted with 14 participants. We sampled their experience in a transdiagnostic manner. That is, we observed how the experience of presence changes both in circumstances appraised as positive (e.g., sexual intimacy) and negative (e.g., psychopathology). Our grounded theory suggests that presence is a phenomenon that is comprised of all available sensory knowledge, however, it …
An Interactionist Approach To Btlg Pride, Lain A.B. Mathers, Jason E. Sumerau
An Interactionist Approach To Btlg Pride, Lain A.B. Mathers, Jason E. Sumerau
The Qualitative Report
Within and beyond Symbolic Interactionism, sociological studies of bisexual, transgender, lesbian, and gay (BTLG) populations have expanded dramatically in the past two decades. Although such studies have invigorated our understanding of many aspects of BTLG life and experience, they have thus far left BTLG Pride relatively unexplored. How do BTLG populations experience Pride, and what insights might such efforts have for sociologically understanding such populations and events? We examine these questions through an interview study of bi+ people (i.e., sexually fluid people who identify as bisexual, pansexual, or otherwise outside of gay/straight binaries; Eisner, 2013). Specifically, we analyze how bi+ …
Assessment Of The Quality Services Of The University Libraries: The Case Of Birjand University Library, Leili Seifi
Assessment Of The Quality Services Of The University Libraries: The Case Of Birjand University Library, Leili Seifi
Library Philosophy and Practice (e-journal)
The study evaluates the quality of services received by the Central Library of Birjand University among users based on LibQual components. The present study is descriptive. Data were collected using the LibQual questionnaire, and its reliability is obtained using Cronbach's alpha test. The statistical population included all users of the Central Library of Birjand University which 150 users were selected by non-proportional stratified sampling. The results of the study showed that the quality of services received in general and in the three components of effect of service, information control, and the library as place, were above average. There was no …
The Clash Of The Commons: An Imagined Library Commons Discourse, Emily Benoff
The Clash Of The Commons: An Imagined Library Commons Discourse, Emily Benoff
Urban Library Journal
The commons has been adopted by LIS as a metaphor for transformational library spaces. However, post-colonial scholarship exposes the material violence and exclusionary practices that coincide(d) with commons-making in Europe and North America. When weighing such assessments against the traditional role of American libraries as mechanisms of colonial values, it becomes necessary for library professionals to critique their continued evocation of commons discourse from a perspective that centers decolonization. Responding to this challenge, I historicize the commons as both an imagined ideology and an actual instrument of power to contextualize Indigenous and post-colonial assessments of commons-making in the settler colonial …
Mentoring: The Factors That Contribute To Persistence To Graduation For African American Males In Predominantly White Institutions In Missouri, Paula Miller
Dissertations
Due to several decisions by the United States Supreme Court in the 19th and 20th centuries, African Americans were granted access to PWI’s of higher education. However, African Americans still face challenges in obtaining post-secondary education. For example, in 2019 – 2020, according to the National Center for Educational Statistics (2021), 13.1% of African Americans graduated with master’s degrees. Additionally, in 2020, 19% of African Americans attained a post-secondary degree in Missouri (Towncharts.com, 2021).
Despite access, the number of African Americans obtaining degrees remains low. And, when the lens is focused on African American males, the numbers are …
Neurodiverse Navigation And Disability Equity In A Nyc Doe Early College Library, Nava Bahrampour, Jess Decourcy Hinds
Neurodiverse Navigation And Disability Equity In A Nyc Doe Early College Library, Nava Bahrampour, Jess Decourcy Hinds
Urban Library Journal
The Bard High School Early College Queens (BHSEC Q) serves high school students who are simultaneously earning college associates degrees. The library works in partnership with a student affinity group called the Abled-Disabled Alliance (ADA). During the 2021-22 school year, the ADA has recommended a library renovation and a disability studies course, among other initiatives. The librarian taught “Disability and Equity in the Library,” to 13 students, many of whom identified as neurodiverse or disabled, and invited them to reflect on their learning needs. The course culminated in research-based proposals to redesign library space and services. This work complements one …
Responses To Validating Versus Reframing Support Strategies As A Function Of Borderline Personality Features And Interpersonal Problems, Stella Nicolaou, Sydney F. Goldberg, Kaley M. Michael, Kathy R. Berenson
Responses To Validating Versus Reframing Support Strategies As A Function Of Borderline Personality Features And Interpersonal Problems, Stella Nicolaou, Sydney F. Goldberg, Kaley M. Michael, Kathy R. Berenson
Psychology Faculty Publications
We examined whether borderline personality features may be differentially associated with reactions to social support strategies involving validation (acknowledging distress as normal) vs. reframing (highlighting opportunities for positive outcomes). After completing self-report measures of their borderline personality features and interpersonal problems, participants rated their reactions to receiving either validation or reframing support (randomly assigned) from a close friend with whom they imagined sharing hypothetical negative experiences. Borderline personality features were associated with less positive responses to reframing than to validation, and a tendency to interpret reframing support as an assertion of dominance. Moderated mediation analyses further showed that associations between …
Test Taking Tips, Zoey Hart, Triniti Joy, Samdine Murray, Conor Reilly
Test Taking Tips, Zoey Hart, Triniti Joy, Samdine Murray, Conor Reilly
University Student Success UNIV 101
- Introduction
- Weeks Before
- What Kind of Test?
- Cramming
- Pretest
- Study Group
- Night Before the Test
- Morning of the Test
- Test Anxiety
- Test Taking Strategies
- Multiple Choice
- True or False
- Open Ended
- Works Cited
The Current - Volume 33 Issue 3, Nova Southeastern University
The Current - Volume 33 Issue 3, Nova Southeastern University
Student Newspapers
No abstract provided.
From The Acting Editor In Chief, Conrad C. Crane
From The Acting Editor In Chief, Conrad C. Crane
The US Army War College Quarterly: Parameters
No abstract provided.
Moving From Probabilistic To Time-Based On-Time Performance (For Practitioners), Miles James Allen Crumley
Moving From Probabilistic To Time-Based On-Time Performance (For Practitioners), Miles James Allen Crumley
PSU Transportation Seminars
On-Time Performance (OTP) is a probabilistic measure that tells the customer the likelihood that the trip they are about to take will arrive "on-time." However, this metric forces the customer to think in terms of a probability of trip timeliness and not an actual time value for how timely the trip will be. This presentation will explore a new way to examine on-time performance by quantifying the timeliness of trips. Customers can then use this information to determine which trip would be the best to take based on when they need to arrive at their destination. Using a system science …
Archives Annual Report, 2021-2022, Meg Miner
Archives Annual Report, 2021-2022, Meg Miner
Administrative Reports
No abstract provided.
Estimation Of Economic Risk From Coastal Natural Hazards In Louisiana, Rubayet Bin Mostafiz
Estimation Of Economic Risk From Coastal Natural Hazards In Louisiana, Rubayet Bin Mostafiz
LSU Doctoral Dissertations
Louisiana, U.S.A., is among the most vulnerable areas globally to coastal natural hazards, with risk vulnerability likely increasing. The risks associated with non-tropical-cyclone hazards in Louisiana’s coastal zone have been understudied. This research enhances present and future (i.e., 2050) Louisiana risk assessment using locally-weighted, model-based hazard frequency/intensity and population projections.
Results suggest that property risks associated with extreme cold temperature and tornado are and will remain costlier than those for hail and lightning. Property risks of extreme cold temperature and hail are projected to decrease with the expected warming temperatures, with those of all four of these hazards peaking in …
The Impact Of The Covid-19 Pandemic On School Psychology Internship Outcomes, Julie Q. Morrison, Kizzy Albritton, Elana Bernstein, Susan C. Davies, Laurice Joseph, Katherine R. Mezher, Jennifer Reynolds, Richard W. Vanvoorhis
The Impact Of The Covid-19 Pandemic On School Psychology Internship Outcomes, Julie Q. Morrison, Kizzy Albritton, Elana Bernstein, Susan C. Davies, Laurice Joseph, Katherine R. Mezher, Jennifer Reynolds, Richard W. Vanvoorhis
Counselor Education and Human Services Faculty Publications
The Ohio Internship Program in School Psychology was forced to adapt abruptly to the changing circumstances brought on by the novel coronavirus (COVID-19) pandemic beginning in March 2020. The purpose of this study was to determine the extent to which the school psychology internship outcomes were negatively affected by the COVID-19 pandemic in terms of supervisors' ratings of intern competencies, the number of students served by interns, and the outcomes of academic and behavior interventions supported by interns. Findings of the annual evaluation of the Ohio Internship Program in School Psychology for the school year directly affected by the pandemic …
The Limits Of Financial Equity: The Federal Reserve, The Depression Of 1921, And The End Of Wilsonian Progressivism, Terril Hebert
The Limits Of Financial Equity: The Federal Reserve, The Depression Of 1921, And The End Of Wilsonian Progressivism, Terril Hebert
LSU Master's Theses
The Limits of Financial Equity: The Federal Reserve, the Depression of 1921, and the End of Wilsonian Progressivism is an examination of monetary policy and centralized macroeconomic planning in the American economy during the inflationary spiral of the 1910s that culminated in the Depression of 1921. Put forward for consideration is the successful populist campaign for agricultural credit equity by the burgeoning Federal Reserve System; set against a backdrop of intentional inflation, world and domestic citizens competed against as the price and supply chain distortions perpetuated by the policing of American commerce by the Food Administration, A. Mitchell Palmer’s Department …
Why Do Senior Officers Sometimes Fail In Character? The Leaky Character Reservoir, Everett S.P. Spain, Katie E. Matthew, Andrew L. Hagemaster
Why Do Senior Officers Sometimes Fail In Character? The Leaky Character Reservoir, Everett S.P. Spain, Katie E. Matthew, Andrew L. Hagemaster
The US Army War College Quarterly: Parameters
This article argues senior officers may fail in character because their rate of character development throughout their careers typically decreases as environmental stressors rise. It conceptualizes character as an open system with both gains and leaks over time and integrates existing scholarship on personality and ethical development to create the Leaky Character Reservoir framework, which it then applies to Army officers’ careers. Military leaders will gain a new understanding of character and find specific actions officers, units, and the US Army can undertake to strengthen the character of its senior officers.
Cognitive Difficulty In The Five Boroughs Of New York City, 2000-2019, Marjorine Henriquez-Castillo
Cognitive Difficulty In The Five Boroughs Of New York City, 2000-2019, Marjorine Henriquez-Castillo
Center for Latin American, Caribbean, and Latino Studies
Introduction:
the percentage of people with cognitive difficulty reported in 2000, 2010, and 2019 among residents in New York City. Specifically, residents from the five boroughs in New York City—Bronx, Brooklyn, Manhattan, Queens, and Staten Island—were included in this analysis.
Methods:
This report uses the American Community Survey PUMS (Public Use Microdata Series) data for all years released by the Census Bureau and reorganized for public use by the Minnesota Population Center, University of Minnesota, IPUMSusa, (https://usa.ipums.org/usa/index.shtml). See Public Use Microdata Series Steven Ruggles, J. Trent Alexander, Katie Genadek, Ronald Goeken, Matthew B. Schroeder, and Matthew Sobek. Integrated Public Use …
Parameters Winter Issue 2022-23, Usawc Press
Parameters Winter Issue 2022-23, Usawc Press
The US Army War College Quarterly: Parameters
No abstract provided.
Conferencia "Definición Y Características De Las Mega-Campañas En El Contexto De Los Juegos De Rol", Marcos O. Cabobianco, Cristo Leon
Conferencia "Definición Y Características De Las Mega-Campañas En El Contexto De Los Juegos De Rol", Marcos O. Cabobianco, Cristo Leon
STEM for Success Resources
Presentación realizada durante el 6º Coloquio de Estudios sobre Juegos de Rol (CEJR) el 18 de noviembre de 2022 en Mérida, Yucatán, México.
Climate Action And Indigenous Land Relations: A Case Study In Nagaland, Northeastern India, Osensang Pongen
Climate Action And Indigenous Land Relations: A Case Study In Nagaland, Northeastern India, Osensang Pongen
USF Tampa Graduate Theses and Dissertations
This research grew out of my interest in the implications of climate action, especially its effects in natural-resource-rich peripheral regions like my home state of Nagaland. This study will be of interest to anyone seeking a deeper understanding of the ways in which global ecodevelopment programs expand and mutate at the micro-scales in Indigenous communities. This includes structural transformations to their Indigenous socio-economic and political lifeworlds, their cosmologies, and their affective relations with their ancestral lands and environment. More broadly, the study draws attention to the growing challenges confronting Indigenous peoples in the Global South who are being seduced by …
Sindh: Floods And Rural Economy ‐ Part Iii, Ishrat Husain Dr.
Sindh: Floods And Rural Economy ‐ Part Iii, Ishrat Husain Dr.
Faculty Research - Newspaper and Magazine Articles
What needs to be done? One of the main reasons for the flooding due to torrential rains this time around rather – than the river levels rising –was that the national waterways have been encroached, the capacity of drainage system such as LBOD was limited and outlets to traditional drains leading to the sea were not functional, desilting of canals had not taken place and repair and maintenance of bund embankments were neglected. A World Bank-SIDA study of 2013 had identified projects to be executed for an integrated drainage system. The works worth Rs42 billion have been delayed for the …
Genome-Transcriptome-Functional Connectivity-Cognition Link Differentiates Schizophrenia From Bipolar Disorder, Jiayu Chen, Zening Fu, Juan R Bustillo, Nora I Perrone-Bizzozero, Dongdong Lin, Jose Canive, Godfrey D Pearlson, Julia M Stephen, Andrew R Mayer, Steven G Potkin, Theo G M Van Erp, Peter Kochunov, L Elliot Hong, Bhim M Adhikari, Ole A Andreassen, Ingrid Agartz, Lars T Westlye, Jing Sui, Yuhui Du, Fabio Macciardi, Faith M Hanlon, Rex E Jung, Jessica A Turner, Jingyu Liu, Vince D Calhoun
Genome-Transcriptome-Functional Connectivity-Cognition Link Differentiates Schizophrenia From Bipolar Disorder, Jiayu Chen, Zening Fu, Juan R Bustillo, Nora I Perrone-Bizzozero, Dongdong Lin, Jose Canive, Godfrey D Pearlson, Julia M Stephen, Andrew R Mayer, Steven G Potkin, Theo G M Van Erp, Peter Kochunov, L Elliot Hong, Bhim M Adhikari, Ole A Andreassen, Ingrid Agartz, Lars T Westlye, Jing Sui, Yuhui Du, Fabio Macciardi, Faith M Hanlon, Rex E Jung, Jessica A Turner, Jingyu Liu, Vince D Calhoun
Faculty, Staff and Student Publications
BACKGROUND AND HYPOTHESIS: Schizophrenia (SZ) and bipolar disorder (BD) share genetic risk factors, yet patients display differential levels of cognitive impairment. We hypothesized a genome-transcriptome-functional connectivity (frontoparietal)-cognition pathway linked to SZ-versus-BD differences, and conducted a multiscale study to delineate this pathway.
STUDY DESIGNS: Large genome-wide studies provided single nucleotide polymorphisms (SNPs) conferring more risk for SZ than BD, and we identified their regulated genes, namely SZ-biased SNPs and genes. We then (a) computed the polygenic risk score for SZ (PRSSZ) of SZ-biased SNPs and examined its associations with imaging-based frontoparietal functional connectivity (FC) and cognitive performances; (b) examined the spatial …