Engineering Commons^™

Conference Program, Weibing Ding, Martina Micheletti, Robert Repetto

Single-Use Technologies III: Scientific and Technological Advancements

No abstract provided.

Full Proceedings, 2018, Jianshun Zhang

International Building Physics Conference 2018

Full conference proceedings for the 2018 International Building Physics Association Conference hosted at Syracuse University.

Qualification Of Low Drift Single-Use Ph Sensors For Use In Single-Use Bioreactor Platforms, Jason Brown, Alexander J. Hodge, Nephi Jones

Single-Use Technologies III: Scientific and Technological Advancements

The biopharmaceutical industry is currently limited by access to low drift, gamma stable, easy-to-integrate single-use pH sensors for application in single-use bioreactors (S.U.B.). Hamilton Company has developed the OneFerm VP 70 sensor, a unique single-use glass electrode, which provides an additional option for customers wishing to implement reliable single-use pH sensing capabilities in the S.U.B. platform. In order to demonstrate the efficacy of these devices, a series of qualification experiments were carried out using a Thermo Fisher Scientific 50L bioprocess container (BPC) custom-fitted with Hamilton OneFerm sensors. BPCs were manufactured in a cGMP facility and allowed to age for a …

An Example Of Thermoset – Silicone, Csilla Kollar

Single-Use Technologies III: Scientific and Technological Advancements

Abstract is not available.

Single-Use Ph Sensor Via A Coplanar Ph Glass Electrode Design, Cd Feng, Robert Garrahy

Single-Use Technologies III: Scientific and Technological Advancements

The elimination of high temperature and high pressure sterilization processes by the advent of Single-Use-Systems (SUS) opens up a new era for the glass electrode based pH sensor. Without the requirement for pretreatment of a pH glass electrode under high temperature and pressure, the classic pH sensing technology delivers a more reliable, more rugged, and more accurate pH measurement. However, the innovative and unique SUS practice also posts new challenges, such as the long shelf-life requirement and the limitation of access to the sensor for calibration once on site,.

At Broadley-James Corporation, a new manufacturing technology has been developed to …

Process Intensification In Biomanufacturing Driven By Advances In Single Use Technologies, Stefan Schmidt

Single-Use Technologies III: Scientific and Technological Advancements

Single use technologies now represent the state of the art in biomanufacturing, but still the full potential of a broad application has not been tapped yet. One strategy that captures most of disposable benefits is process intensification. Here single use systems are optimized to achieve similar output levels as traditional stainless-steel facilities but at much lower capital expenditure, smaller footprints and faster implementation times. This presentation gives an overview on current approaches, describes the opportunities and limits of disposables and delivers recommendations to what should be done by suppliers and users in the near future.

Single Use Plastic Settlers For Clarifying Cell Culture Broth, Selective Removal Of Dead Cells And Affinity Capture Of Antibodies On Protein A Beads, Dhinakar Kompala, Mark Harris, Christopher Glascock, Premsingh Samuel

Single-Use Technologies III: Scientific and Technological Advancements

We have redesigned the successful “inclined settler” technology used as a selective cell retention device in mammalian cell perfusion bioreactor cultures into a more compact and easily scalable design using cylindrical and conical geometries. Through this novel settler design, we have achieved 6 – 10 x more settling area for the same footprint, compared to the traditional multi-plate or lamellar rectilinear scale up design. Using this compact settler design, we have demonstrated significant clarification of the smaller yeast Pichia pastoris cells in continuous harvest or settler effluent stream and high cell densities (700 – 1000 O.D.) in perfusion bioreactors operated …

Purity Testing Protocols For Silicone Tubing, Csilla Kollar, Lise Tan-Sien-Hee

Single-Use Technologies III: Scientific and Technological Advancements

Silicone tubing products are widely used in critical biopharmaceutical processes including final fill and other aseptic operations that require high purity product contact components.

At Dow we have developed reliable and rigorous methods based on the industry standards for particulates, endotoxins and bioburden to test our Platinum-catalyzed silicone tubing family. The tests were conducted per the USP ‹788› Particulate Matter in Injection, the USP ‹85› Bacterial Endotoxins Test, and the ISO 11737-1 Sterilization of medical devices — Microbiological methods — Part 1: Determination of a population of microorganisms on products.

• Method 2 Microscopic Particle Count Test of USP ‹788› was …

Map Based Discovery Of Hydrologic Data In The Hydroshare Collaboration Environment, Zhaokun Xue, Alva Couch, David G. Tarboton

Civil and Environmental Engineering Faculty Publications

Data discovery refers to the process of locating pre-existing data for use in new research. In the HydroShare collaboration environment for water science, there are more than twenty kinds of data that can be discovered, including data from specific sites on the globe, data corresponding to regions on the globe, and data with no geospatial meaning, such as laboratory experiment results. This paper discusses lessons learned in building a data discovery system for HydroShare. This was a surprisingly difficult problem; default behaviors of software components were unacceptable, use cases suggested conflicting approaches, and crafting a geographic view of a large …

Critical Theoretical Frameworks In Engineering Education: An Anti-Deficit And Liberative Approach, Joel A. Mejia, Renata A. Revelo, Idalis Villanueva, Janice Mejia

Engineering Education Faculty Publications

The field of engineering education has adapted different theoretical frameworks from a wide range of disciplines to explore issues of education, diversity, and inclusion among others. The number of theoretical frameworks that explore these issues using a critical perspective has been increasing in the past few years. In this review of the literature, we present an analysis that draws from Freire’s principles of critical andragogy and pedagogy. Using a set of inclusion criteria, we selected 33 research articles that used critical theoretical frameworks as part of our systematic review of the literature. We argue that critical theoretical frameworks are necessary …

“There Is Never A Break”: The Hidden Curriculum Of Professionalization For Engineering Faculty, Idalis Villanueva, Taya Carothers, Marialuisa Di Stefano, Md. Tarique Hasan Kahan

Engineering Education Faculty Publications

The purpose of this exploratory special issue study was to understand the hidden curriculum (HC), or the unwritten, unofficial, or unintended lessons, around the professionalization of engineering faculty across institutions of higher education. Additionally, how engineering faculty connected the role of HC awareness, emotions, self-efficacy, and self-advocacy concepts was studied. A mixed-method survey was disseminated to 55 engineering faculties across 54 institutions of higher education in the United States. Quantitative questions, which centered around the influences that gender, race, faculty rank, and institutional type played in participants’ responses was analyzed using a combination of decision tree analysis with chi-square and …

Physical Modeling Of Flow Nets In Groundwater And Determination Of Hydraulic Conductivity, Hannah Nicholas, Moses Karakouzian

AANAPISI Poster Presentations

The goal of this study is to physically model the paths that water particles take through soil, and estimate hydraulic conductivity for several soil configurations. Water paths, or flow lines, are shown by injecting dye into sand contained in a rectangular acrylic glass tank with a vertical barrier in the center; water is poured on one side of the tank and a pump is used to maintain constant head loss. If flow lines are formed, a flow net is to be drawn using photos of the tank and hydraulic conductivity is to be calculated.

This project consists of four phases: …

Coir Fiber Reinforced Concrete, Jose De La Serna, Moses Karakouzian

AANAPISI Poster Presentations

This poster exhibits the testing and research done on general Portland Cement Concrete with the addition of coir (coconut) fibers as reinforcement. Using the fundamental constituents of cement (water, cement, fine and coarse aggregate) and processed coir fiber, concrete specimens were batched to test for compressive and flexural strengths (per appropriate ASTM standards). Cylindrical and rectangular beam specimens were subjected to loadings until failure occurred. The capacity and modes of failures of the specimens were observed. It was determined that:

• The addition of processed coir fibers decreases the overall strength of general Portland Cement Concrete. • The tested concrete’s …

Simulation Of The Oxygen Reduction Reaction (Orr) Inside The Cathode Catalyst Layer (Ccl) Of Proton Exchange Membrane Fuel Cells Using The Kinetic Monte Carlo Method, Baosheng Bai, Yi-Tung Chen

Mechanical Engineering Faculty Research

In this paper, a numerical model of the kinetic Monte Carlo (KMC) method has been developed to study the oxygen reduction reaction (ORR) that occurs inside the cathode catalyst layer (CCL). Firstly, a 3-D model of the CCL that consists of Pt and carbon spheres is built using the sphere packing method; secondly, an efficient procedure of the proton-oxygen reaction process is developed and simulated. In the proton-oxygen reaction process, all of the continuous movements of protons and oxygen are considered. The maximum reaction distance is determined to be 8 Å. The input pressures of protons and oxygen are represented …

Evaluation Of Heat Efficiency Of Flat Solar Air Heaters, E.S. Abbasov, M.A. Umurzakova

Journal of Tashkent Institute of Railway Engineers

The article discusses the issues of increasing the thermal efficiency of flat solar air collectors. To achieve the goal, the authors propose to use methods of wall intensification of heat transfer (using the diffuser-confusor channels and surfaces with spherical depressions). In the article formulas for calculating the thermal efficiency and the relative thermal performance of the collectors are developed

Theoretical And Experimental Analysis Of The Process Of Defosphoration Of Steel Used For Parts Of The Mobile Composition Of Railway Transport, N.K. Tursunov, Ya.O. Ruzmetov

Journal of Tashkent Institute of Railway Engineers

Analyzed the process of dephosphoration of steel in coreless induction furnaces with a capacity of 6 tones. As the tested metal used steel grade 20GL. An experimental study of the process of steel dephosphoration was carried out in induction furnace with the use of solid slag-forming mixtures

Some Aspects Of Studying The Structure Of Construction Materials By The Method Of Mercury Purometry, Anvar Ishanovich Adilkhodjayev, I.A. Kadirov

Journal of Tashkent Institute of Railway Engineers

The article gives a classification of methods for controlling the porous structure of materials. The parameters of the porosity of aerated concrete were investigated by the method of mercury porosimetry. The method of mercury porosimetry is based on the fact that a liquid that does not wet a solid penetrates into its pores only when exposed to external pressure. The total porosity of aerated concrete according to mercury porosimetry is 49.28%

The Santa Clara, 2018-09-20, Santa Clara University

The Santa Clara

No abstract provided.

Coupled Thermally-Enhanced Bioremediation And Renewable Energy Storage System: Conceptual Framework And Modeling Investigation, Ali Moradi, Kathleen M. Smits, Jonathan O. Sharp

Civil Engineering Faculty Publications - Archive

This paper presents a novel method to couple an environmental bioremediation system with a subsurface renewable energy storage system. This method involves treating unsaturated contaminated soil using in-situ thermally enhanced bioremediation; the thermal system is powered by renewable energy. After remediation goals are achieved, the thermal system can then be used to store renewable energy in the form of heat in the subsurface for later use. This method can be used for enhanced treatment of environmental pollutants for which temperature is considered a limiting factor. For instance, this system can be used at a wide variety of petroleum-related sites that …

Removal Efficiencies, Uptake Mechanisms And Competitive Effects Of Copper And Zinc In Various Stormwater Filter Media, Emily Heleva-Ponaski

Dissertations and Theses

Polluted stormwater, if not treated, can compromise water quality throughout our hydrologic cycle, adversely affecting aquatic ecosystems. Common stormwater pollutants, copper and zinc, have been identified as primary toxicants in multiple freshwater and marine environments. For small-scale generators, stormwater management can be cumbersome and implementation of common BMPs impractical thus catch basins are popular though not the most environmentally conscious and sustainable option. This study aims to characterize the potential of a mobile media filter operation for the treatment and on-site recycling of catch basin stormwater. The removal capacities of various commercially available filter media (e.g. a common perlite; Earthlite™, …

Nanoflower-Like Bi2moo6/Ag3po4 In Water Treatment, Xavier Morgan-Lange, Jaeyun Moon, Kaleab Ayalew

McNair Poster Presentations

• Environmental issues continue to intensify causing natural resources such as clean water to become increasingly scarce while demand only continues to grow. • Some of the most effective measures taken appear to be bioremediation tactics and their synthetic counterparts. • A critical area of interest are semi-conducting photocatalytic nanomaterials that take advantage of the photo-electric effect and use the introduction of ultra violet (UV) and visible light to induce oxidation and reduction reaction in p-type semiconductors. This results in the decomposition of certain pollutants and/or deactivates certain microbes in water. • These materials have the potential to operate using …

Effects Of Different Retail Packaging Materials On The Shelflife Of Dehusked Foxtail Millet, Pooran Pragnya Joshi, Ravikumar Biradar, Prakash Mathad, Vikas Jha

Journal of Applied Packaging Research

Millets are in the family of cereals grown globally with differential importance across continents and within regions of the world. Cereals are staple foods for a large proportion of the world population. The present investigation was carried out to find out the effect of different retail packaging material on the shelf-life of dehusked foxtail millet. The foxtail millet was procured at local Raichur market. Physical properties of dehusked foxtail millet viz., Particle density, Bulk density, Angle of repose, Coefficient of internal friction, Coefficient of external friction, Length, Breadth, Thickness, size and Spherecity were found to be 1.34 g/cc , 0.87 …

Toward Autonomous Wall-Climbing Robots For Inspection Of Concrete Bridges And Tunnels, Jizhong Xiao

INSPIRE Archived Webinars

In addition to visual inspection for surface flaws, inspectors are often required to detect subsurface defects (e.g., delamination and voids) using nondestructive evaluation (NDE) instruments, such as ground penetration radar (GPR) and impact sounding device, in order to determine the structural integrity of bridges and tunnels. In these cases, access to critical locations for reliable and safe inspections is a challenge.

Since 2002, Dr. Jizhong Xiao’s group has developed four generations of wall-climbing robots for NDE inspection of bridges and tunnels. These robots combine the advantages of aerodynamic attraction and suction to achieve a desirable balance of strong adhesion and …

Deep Rc: Enabling Remote Control Through Deep Learning, Jaron Ellingson, Gary Ellingson, Tim Mclain

Student Works

Human remote-control (RC) pilots have the ability to perceive the position and orientation of an aircraft using only third-person-perspective visual sensing. While novice pilots often struggle when learning to control RC aircraft, they can sense the orientation of the aircraft with relative ease. In this paper, we hypothesize and demonstrate that deep learning methods can be used to mimic the human ability to perceive the orientation of an aircraft from monocular imagery.

This work uses a neural network to directly sense the aircraft attitude. The network is combined with more conventional image processing methods for visual tracking of the aircraft. …

Wireless Sensor Networks For Long-Term Monitoring Of Urban Noise, Courtney Peckens, Cédric Porter, Taylor Rink

Faculty Publications

Noise pollution in urban environments is becoming increasingly common and it has potential to negatively impact people’s health and decrease overall productivity. In order to alleviate these effects, it is important to better quantify noise patterns and levels through data collection and analysis. Wireless sensor networks offer a method for achieving this with a higher level of granularity than traditional handheld devices. In this study, a wireless sensing unit (WSU) was developed that possesses the same functionality as a handheld sound level meter. The WSU is comprised of a microcontroller unit that enables on-board computations, a wireless transceiver that uses …

Approaches To Open Source 3-D Printable Probe Positioners And Micromanipulators For Probe Stations, Iiro Hietanen, Ismo T. S. Heikkinen, Hele Savin, Joshua M. Pearce

Department of Materials Science and Engineering Publications

Three types of highly-customizable open source probe positioning systems are evaluated: (a) mostly 3-D printed, (b) partially printed using OpenBeam kinematic constraints, and (c) a 3-level stack of low-cost commercial single axis micropositioners and some printed parts. All systems use digital distributed manufacturing to enable bespoke features, which can be fabricated with RepRap-class 3-D printer and easily accessible components. They are all flexible in material choice for custom components. The micropositioners can be set up for left-right use and flat or recessed configurations using either mechanical or magnetic mounting. All systems use a manual probe holder that can be customized …

Minutes & Seconds: The Scientists, Patrick Aievoli

Zea E-Books Collection

Minutes & Seconds, is a captivating intelligible read for those who strive to understand where the “what if” moment has gone. Succeeding his other captivating books, Aievoli’s deep introspective lens dials his readers in to awaken the proverbial sleeping giant inside of our consciousness. He designs an insightful exciting romp through the surreal landscape of our society and illustrates how various pioneers have lead us to a crossroads. I’m truly impressed with Aievoli’s perspicacious comprehension of where digital has taken us through the hands of these select individuals. --Sequoyah Wharton

In creating Minutes & Seconds, Aievoli has assembled an interesting …

Cubesat Active Thermal Management In Support Of Cooled Electro-Optical Instrumentation For Advanced Atmospheric Observing Missions, Lucas Anderson, Charles Swenson, Ryan Davidson, Arthur J. Mastropietro, Elham Maghsoudi, S. Luong, Stefano Cappucci, I. Mckinley

Electrical and Computer Engineering Faculty Publications

The need for advanced cooled electro-optical instrumentation in remote observations of the atmosphere is well known and demonstrated by SABER on the TIMED mission. The relatively new use of small satellites in remote earth observing missions as, well as the challenges, are epitomized by the upcoming NOAA EON-IR 12U CubeSat missions. These advanced CubeSat missions, which hope to accomplish scientific objectives on the same scale as larger more traditional satellites, require advanced miniaturized cryocoolers and active methods for thermal management and power control. The active CryoCubeSat project (ACCS) is a demonstration of such a technology. Utilizing Ultrasonic Additive Manufacturing (UAM) …

Nasa Awards Prestigious Fellowship To Usu Engineering Graduate Student | College Of Engineering, Usu College Of Engineering

College of Engineering News

Utah State University’s Jeff Taylor is one of five students nationwide to receive a fellowship from NASA’s top aeronautics research division.

Reducing Exposures Traffic-Related Air Pollution And Urban Building Design, Elliott T. Gall, Linda George

Mechanical and Materials Engineering Faculty Publications and Presentations

No abstract provided.