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Full-Text Articles in Engineering

Analysis Of An Outdoor Pilot-Scale Rotating Algae Biofilm Reactor For Power Optimization, Ash-Enhanced Productivity, And Nutrient Uptake, Peter F. Jeppesen Dec 2024

Analysis Of An Outdoor Pilot-Scale Rotating Algae Biofilm Reactor For Power Optimization, Ash-Enhanced Productivity, And Nutrient Uptake, Peter F. Jeppesen

All Graduate Theses and Dissertations, Fall 2023 to Present

Outdoor testing of a rotating algae biofilm reactor (RABR) was performed to see how well it could remove nutrients from water and produce algae. By adjusting the operation settings, we found the lowest power needed to remove nitrogen and phosphorus. The lowest power values needed were 1.36 kWh per kilogram of nitrogen and 20.1 kWh per kilogram of phosphorus. The algae production rate reached a maximum of 7.09 grams per square meter per day. Detailed analysis showed that the reactor worked like a continuous flow system, and the performance was influenced by factors including light and temperature. The results also …


Study Of Different Treatment Strategies In Epidemic Models Using Nonlinear Model Predictive Control, Hector Puebla, Luis A. Ricardez-Sandoval, Priti Kumar Roy Nov 2024

Study Of Different Treatment Strategies In Epidemic Models Using Nonlinear Model Predictive Control, Hector Puebla, Luis A. Ricardez-Sandoval, Priti Kumar Roy

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Energy Performance Efficiency And Cost Analysis By Bim-Based Model Simulation For Residential Buildings In Egypt, Bishoy Magdy Tawfeeq Sidhom Oct 2024

Energy Performance Efficiency And Cost Analysis By Bim-Based Model Simulation For Residential Buildings In Egypt, Bishoy Magdy Tawfeeq Sidhom

Mansoura Engineering Journal

Technology plays an important role in meeting the needs of users, as it is considered one of the important tools in the BIM construction and industry, which many engineering sectors in projects have taken an interest in using by creating a social and healthy environment. Therefore, Egypt was interested in resorting to the establishment of stations to take advantage of renewable energy sources to produce energy and reduce the consumption of non-renewable energy sources, including reducing the consumption of cooling devices in the summer to save energy and costs. BIM helps designers design buildings quickly, the ability to analyze information, …


Scaleddetr: An Alight Weight Object Detection Model For Autonomous Driving, Ali Elhenidy, Labib Mohamed, Amira Yassien, Mahmoud Saafan Oct 2024

Scaleddetr: An Alight Weight Object Detection Model For Autonomous Driving, Ali Elhenidy, Labib Mohamed, Amira Yassien, Mahmoud Saafan

Mansoura Engineering Journal

End-to-end object detection is one of the recent trends in object detection; however, it is time- and memory-consuming due to the Transformer encoder-decoder (TED) module. Detection TRansformer (DETR) is the first end-to-end object detector using a TED architecture. Despite achieving competitive performance, it suffers from slow convergence due to a long sequence of attention and the whole image. In this paper, ScaledDETR is proposed to handle the slow convergence issue in DETR and speed up the training process by implementing end-to-end detection based on the latest efficient backbone with fewer parameters. ScaledDETR proposes an efficient model with fewer parameters by …


13th International Conference On Business, Technology And Innovation 2024, University For Business And Technology - Ubt Oct 2024

13th International Conference On Business, Technology And Innovation 2024, University For Business And Technology - Ubt

UBT International Conference

Welcome to IC – UBT 2024

UBT Annual International Conference is the 13th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make …


Basic Psychological Needs Satisfaction And Well-Being Among Seafarers: An Investigation Of Interaction Effects Through The Lens Of Self-Determination Theory, Nong Vuong Phi, Kung Don Ye, Feng Ming Tsai, Hsiao Chao Hsieh, Shiou-Yu Chen Oct 2024

Basic Psychological Needs Satisfaction And Well-Being Among Seafarers: An Investigation Of Interaction Effects Through The Lens Of Self-Determination Theory, Nong Vuong Phi, Kung Don Ye, Feng Ming Tsai, Hsiao Chao Hsieh, Shiou-Yu Chen

Journal of Marine Science and Technology

Enhancing employee well-being is a primary goal for enterprise sustainable development. Although seafarers represent a major human resource in the maritime industry, the distinctive demands of their profession often compel them to compromise on certain elements in fulfilling their basic psychological needs, thereby contributing to mental health challenges. Recently, COVID-19 and its associated border control measures have prolonged the voyages of seafarers, drawing public attention to the topic of seafarer well-being. In this study, self-determination theory was used to explore the effects of autonomy, competence, and relatedness as fundamental psychological needs on seafarer well-being. After the independent effects of these …


An Experiment Study On Implementing Syngas On A Small Generator Set, Bui Van Chinh, Khong Vu Quang, Khanh Nguyen Duc Oct 2024

An Experiment Study On Implementing Syngas On A Small Generator Set, Bui Van Chinh, Khong Vu Quang, Khanh Nguyen Duc

ASEAN Journal on Science and Technology for Development

This paper presents an experiment on syngas's influence on the performance and pollutant characteristics of a mechanical diesel engine generator set. Using syngas as an external fuel is good for medium and light loads of less than 80%. While a moderate substitution of syngas will contribute to good performance at high loads, a larger level of syngas provided may degrade engine performance. The brake-specific energy consumption rises as the replacement syngas flow increases. Using syngas as an external fuel to substitute for a part of the diesel might cause the engine to perform unstablely. The more syngas replacements, the greater …


Efficient Real-Time Droplet Tracking In Crop-Spraying Systems, Troung Nhut Huynh, Travis Burgers, Kim-Doang Nguyen Oct 2024

Efficient Real-Time Droplet Tracking In Crop-Spraying Systems, Troung Nhut Huynh, Travis Burgers, Kim-Doang Nguyen

Mechanical Engineering Faculty Publications

Spray systems in agriculture serve essential roles in the precision application of pesticides, fertilizers, and water, contributing to effective pest control, nutrient management, and irrigation. These systems enhance efficiency, reduce labor, and promote environmentally friendly practices by minimizing chemical waste and runoff. The efficacy of a spray is largely determined by the characteristics of its droplets, including their size and velocity. These parameters are not only pivotal in assessing spray retention, i.e., how much of the spray adheres to crops versus becoming environmental runoff, but also in understanding spray drift dynamics. This study introduces a real-time deep learning-based approach for …


Advances In Biomedical Research And Treatments: What Is Acceptable?, Michael L. Clancy, Khalid M. Iskandarani, Mitchell C. Mccrea Oct 2024

Advances In Biomedical Research And Treatments: What Is Acceptable?, Michael L. Clancy, Khalid M. Iskandarani, Mitchell C. Mccrea

Journal of Health Ethics

This study investigated the technology acceptance (TA) of twenty-first century biomedical treatments by adults in the United States. A new TA instrument was created, using five distinct levels: (1) Healing and Prevention, (2) Replacement Organs, (3) Enhancements-Medical, (4) Enhancements-Discretionary, and (5) Transhumans. An on-line survey produced 353 usable responses, which showed distinct patterns for each of five biomedical treatment levels. There was clear support for Levels 1–3, but very strong opposition to Levels 4–5. The TA finding draws the line between which human interventions are acceptable versus others that should be prohibited through public policies and medical guidelines.


Radiopaque Femnn-Mo Composite Drawn Filled Tubing Wires For Braided Absorbable Neurovascular Devices, Adam J. Griebel, Petra Maier, Henry D. Summers, Benjamin Clausius, Isabella Kanasty, Weilue He, Nicholas Peterson, Carolyn Czerniak, Alexander A. Oliver, David F. Kallmes, Ramanathan Kadirvel, Jeremy E. Schaffer, Roger J. Guillory Oct 2024

Radiopaque Femnn-Mo Composite Drawn Filled Tubing Wires For Braided Absorbable Neurovascular Devices, Adam J. Griebel, Petra Maier, Henry D. Summers, Benjamin Clausius, Isabella Kanasty, Weilue He, Nicholas Peterson, Carolyn Czerniak, Alexander A. Oliver, David F. Kallmes, Ramanathan Kadirvel, Jeremy E. Schaffer, Roger J. Guillory

Michigan Tech Publications, Part 2

Flow diverter devices are small stents used to divert blood flow away from aneurysms in the brain, stagnating flow and inducing intra-aneurysmal thrombosis which in time will prevent aneurysm rupture. Current devices are formed from thin (∼25 μm) wires which will remain in place long after the aneurysm has been mitigated. As their continued presence could lead to secondary complications, an absorbable flow diverter which dissolves into the body after aneurysm occlusion is desirable. The absorbable metals investigated to date struggle to achieve the necessary combination of strength, elasticity, corrosion rate, fragmentation resistance, radiopacity, and biocompatibility. This work proposes and …


Nanopore Signal Deviations From Pseudouridine Modifications In Rna Are Sequence-Specific: Quantification Requires Dedicated Synthetic Controls, Amr Makhamreh, Sepideh Tavakoli, Ali Fallahi, Xinqi Kang, Howard Gamper, Mohammad Nabizadehmashhadtoroghi, Miten Jain, Ya-Ming Hou, Sara H Rouhanifard, Meni Wanunu Sep 2024

Nanopore Signal Deviations From Pseudouridine Modifications In Rna Are Sequence-Specific: Quantification Requires Dedicated Synthetic Controls, Amr Makhamreh, Sepideh Tavakoli, Ali Fallahi, Xinqi Kang, Howard Gamper, Mohammad Nabizadehmashhadtoroghi, Miten Jain, Ya-Ming Hou, Sara H Rouhanifard, Meni Wanunu

Department of Biochemistry and Molecular Biology Faculty Papers

Chemical modifications to mRNA respond dynamically to environmental cues and are important modulators of gene expression. Nanopore direct RNA sequencing has been applied for assessing the presence of pseudouridine (ψ) modifications through basecalling errors and signal analysis. These approaches strongly depend on the sequence context around the modification, and the occupancies derived from these measurements are not quantitative. In this work, we combine direct RNA sequencing of synthetic RNAs bearing site-specific modifications and supervised machine learning models (ModQuant) to achieve near-analytical, site-specific ψ quantification. Our models demonstrate that the ionic current signal features important for accurate ψ classification are sequence …


2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute Sep 2024

2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute

Kentucky Water Resources Annual Symposium

No abstract provided.


2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute Sep 2024

2024 Kentucky Water Resources Annual Symposium, Kentucky Water Research Institute

Kentucky Water Resources Annual Symposium

The program and proceedings contains details of the 2024 Kentucky Water Resources Symposium, including presentations, award winners, and poster presentations.

This symposium was planned and conducted as a part of the state water resources research institute annual program that is supported by Grant/Cooperative Agreement Number G21AP10631-02 from the United States Geological Survey (USGS). The contents of this proceedings document and the views and conclusions presented at the symposium are solely the responsibility of the individual authors and presenters and do not represent the official views of the USGS or of the symposium organizers and sponsors. This publication is produced with …


Polyvinyl Alcohol–Red Cabbage Nanofibers As Ph-Responsive Freshness Sensors For Advanced Food Packaging Technology, Foliatini Foliatini, Singgih Wibowo, Henny Rochaeni, Suhartini Suhartini, Fachrurrazie Fachrurrazie, Arzzaq Imanda Prianditya, Pradnadia Putri Hadriansyah, Naura Athira Putri Siregar, Novi Nurpadilah, Putri Alfiani, Maudi Rahim, Endah Sriwahyuni Sep 2024

Polyvinyl Alcohol–Red Cabbage Nanofibers As Ph-Responsive Freshness Sensors For Advanced Food Packaging Technology, Foliatini Foliatini, Singgih Wibowo, Henny Rochaeni, Suhartini Suhartini, Fachrurrazie Fachrurrazie, Arzzaq Imanda Prianditya, Pradnadia Putri Hadriansyah, Naura Athira Putri Siregar, Novi Nurpadilah, Putri Alfiani, Maudi Rahim, Endah Sriwahyuni

Makara Journal of Science

The development of innovative food packaging technologies, particularly those capable of monitoring freshness, has become increasingly important in the food industry. This research explores the development of a pH-responsive freshness sensor using polyvinyl alcohol–red cabbage (PVA/RC) nanofibers. The nanofibers are fabricated through the electrospinning technique and meticulously analyzed via scanning electron microscopy, Fourier-transform infrared (FTIR) spectroscopy, and differential scanning calorimetry (DSC). The results underscore the fine structure of the nanofiber matrix, with an average diameter of ~68 nm. FTIR analysis substantiates the presence of anthocyanin compounds from RC within the PVA/RC nanofibers, which confirms the integration of beneficial components into …


An Optimal Schedule Recovery Model For Transportation Carriers Under Uncertain Typhoon Disruption Periods, Yi-Chun Chen, Shangyao Yan Sep 2024

An Optimal Schedule Recovery Model For Transportation Carriers Under Uncertain Typhoon Disruption Periods, Yi-Chun Chen, Shangyao Yan

Journal of Marine Science and Technology

Due to the unsettled weather conditions caused by typhoons, it is not possible to forecast the time when a typhoon will arrive or depart accurately. The uncertainty regarding the duration of typhoon disruptions makes it challenging for transportation carriers to efficiently adjust their schedules. In this study, to deal with the problem of airline fleet rerouting, flight rescheduling, and passenger reassignment for uncertain disruption periods caused by a typhoon, we utilize network flow techniques with the concept of probability to construct a stochastic model for minimizing the total operating costs. A heuristic algorithm based on the divide-and-conquer technique is adopted …


Chacahoula 2024, Vol 91, Alayna Pellegrin Sep 2024

Chacahoula 2024, Vol 91, Alayna Pellegrin

Chacahoula

MERGING REALITIES:

The 2023 issue of Chacahoula includes December 2023 and May 2024 graduating classes, as well as stunning photography of Week of Welcome, Homecoming, Mardi Gras, and Spring Fever. With features covering notable students, faculty, and staff, this year's time capsule beautifully preserves an academic year in the life of the University of Louisiana at Monroe.


Irrigation Pumping Plants: Energy Consumption And Pumping Plant Performance, Class Handout, Derek M. Heeren, Saleh Taghvaeian, Abia Katimbo, Xin Qiao Sep 2024

Irrigation Pumping Plants: Energy Consumption And Pumping Plant Performance, Class Handout, Derek M. Heeren, Saleh Taghvaeian, Abia Katimbo, Xin Qiao

Open Educational Resources for Engineering

Irrigation can be a large contributor to energy consumption on an irrigated farm. It is important to understand factors that impact irrigation energy use and to identify opportunities to reduce energy consumption. This class handout introduces a set of equations for calculating energy consumption for an irrigation pumping plant based on flow conditions and pump efficiency. It also presents typical values for motor performance (including both electric motors and internal combustion engines) in both SI and USCS units. Finally, the handout introduces the concept of a field evaluation of an irrigation pumping plant along with the Nebraska Pumping Plant Performance …


Prediction Of Mooring System Characteristics Of The Floating Barge Using Deep Neural Networks, Janghoon Seo, Dong-Woo Park Sep 2024

Prediction Of Mooring System Characteristics Of The Floating Barge Using Deep Neural Networks, Janghoon Seo, Dong-Woo Park

Journal of Marine Science and Technology

The present study establishes deep learning models to predict the tensions and inclinations of mooring lines of a floating barge and verifies applicability of these models. Hydrodynamic and mooring analyses are conducted on the dataset used for the deep learning models. Three types of neural network models include a deep neural network (DNN) with input data representing the six degrees of freedom motions of a floating barge, convolutional neural network (CNN) with input images of the floating barge and mooring lines on a horizontal plane, and hybrid neural network (HNN) that consolidates the characteristics of DNN and CNN models. The …


Mapping Of The Potential To Substitute Plastic In Food Packaging In Finnish Supermarkets, Taina Lahtinen, Kirsi Kataja, Jari Viitanen, Vinay Kumar, Jussi Lahtinen, Ali Harlin Sep 2024

Mapping Of The Potential To Substitute Plastic In Food Packaging In Finnish Supermarkets, Taina Lahtinen, Kirsi Kataja, Jari Viitanen, Vinay Kumar, Jussi Lahtinen, Ali Harlin

Journal of Applied Packaging Research

Single-use plastics (SUP), which are extensively utilized in food packaging, are one notable cause for the constantly growing littering issue. This novel study is one of the first attempts to systemically analyze food packaging data to reveal the potential for plastic packaging material reduction or substitution by utilizing a primary packaging material summary of single items sold in Finnish supermarkets. The outcome of the study indicates considerable dissimilarities among product groups concerning used packaging materials, weight, share of plastic, and sales volume. The analysis identified sweets and ready-to-eat meals as product groups for which there is a clear need, but …


Integrated Environmental Vulnerability Assessment And Adaptation Strategies For Coastal Areas Under Sustainable Development, Lien-Kwei Chien, Yu-Chi Li, Chia-Feng Hsu Sep 2024

Integrated Environmental Vulnerability Assessment And Adaptation Strategies For Coastal Areas Under Sustainable Development, Lien-Kwei Chien, Yu-Chi Li, Chia-Feng Hsu

Journal of Marine Science and Technology

This research focuses on the holistic management and environmental vulnerability of coastal areas in Taiwan within the framework of sustainable development. With economic and social growth gravitating towards coastal regions, the strain on the natural environment is increasing. Therefore, discovering a balance between economic progress and environmental conservation is paramount. To decipher the vulnerability of Taiwan's coastal zones, this study first defines ‘Integrated Environmental Vulnerability of Coastal Areas.’Key vulnerability factors were identified across environmental, social, and economic dimensions. Seven core determinants were determined using the Fuzzy Delphi method: biodiversity, coastal erosion, water pollution, population density, population aging, land utilization, and …


Evalution Of The Ability To Infer Tilt Angle And Size Distributions Of Fish Using A Broadband Scientific Echosounder Based On Simulation, Jing Liu Sep 2024

Evalution Of The Ability To Infer Tilt Angle And Size Distributions Of Fish Using A Broadband Scientific Echosounder Based On Simulation, Jing Liu

Journal of Marine Science and Technology

The biological information, such as species, size, and tilt angle, is crucial for converting the echo data into biomass information in acoustic surveys. Typically, the information can be obtained through trawl net sampling or underwater camera observations. However, both methods have some limitations. To overcome these limitations, scientists have utilized inversion methods with multi-frequency and broadband echosounders to derive biological information about fish, plankton, and krill. However, evaluating the reliability and accuracy of these inversion methods has been challenging due to the difficulty in obtaining accurate biological information. In this study, a numerical simulation method was used to generate fish …


A Marine Knowledge System For Ocean Affairs: Integrating Data, Evaluating Usage, And Enabling Sustainable Marine Management, Yu-Jen Pan Sep 2024

A Marine Knowledge System For Ocean Affairs: Integrating Data, Evaluating Usage, And Enabling Sustainable Marine Management, Yu-Jen Pan

Journal of Marine Science and Technology

This study presents the evolution and assessment of the Marine Knowledge Education System (MKES), designed to improve user acceptance among students in professional marine science courses in Taiwan. The MKES leverages real-world maritime cases from the General Coast Guard Administration and is built upon existing technologies like cloud services, social networks, and data analysis tools. The technology acceptance model (TAM) provides the theoretical underpinning for the assessment of user confidence. Data was collected from 190 participants through purposive sampling. Path analysis confirmed all hypothesized relationships within the TAM with statistical significance (p < 0.001). Additionally, paired-sample t-tests revealed a significant increase in student acceptance of the MKES after integrating it into the marine science curriculum. These findings underscore the capacity of the MKES as a digital learning tool to enrich course pedagogy and improve student learning outcomes, thereby offering valuable support in advancing the education of professional marine managers.


Resting-State Eeg Microstate Features For Major Depressive Disorder Classification, George M. V. Quinn Sep 2024

Resting-State Eeg Microstate Features For Major Depressive Disorder Classification, George M. V. Quinn

Dissertations, Theses, and Capstone Projects

Neuroimaging studies have revealed consistent abnormalities in functional connectivity within specific neural networks that may serve as biomarkers for major depressive disorder (MDD). It is important to find inexpensive, non-invasive techniques that target these biomarkers to make diagnosis easier and more objective. EEG microstates are quasi-stable potential topographies that are thought to reflect the quasi-stable network activity of the underlying neural generators. MDD has been shown to alter features of the four canonical EEG microstates (A, B, C, D) with some conflicting results. The most consistent network abnormalities in MDD are found in the anterior default mode network, and this …


Development Of A Disc Blade Cutting System For Sesame Harvesting: Determination Of Operating Criteria And Energy Requirements, Selcuk Ugurluay, Gamze Genc Sep 2024

Development Of A Disc Blade Cutting System For Sesame Harvesting: Determination Of Operating Criteria And Energy Requirements, Selcuk Ugurluay, Gamze Genc

The Philippine Agricultural Scientist

This study aimed to explore the use of rotary disc blades in cutting, since the mowing units used in sesame harvesting contain many parts, require frequent lubrication, and have vibration problems. An experimental setup with a disc blade working on a cut-mowing system based from harvesting methods of sesame plants was designed and fabricated. The most suitable cutting criteria which are blade edge types (30°-30°, 30°-Flat, 45°-45°, 45°-Flat) and disc blade diameters (150, 180, and 210 mm) were determined for shearing and disc cutting action. The lowest cutting energy was consumed by the disc blade with a 30°-wedge angle at …


A P-Graph Approach For Planning Sustainable Rice Straw Management Networks, Victoria Migo Sumagang Maria, Michael Angelo B. Promentilla Sep 2024

A P-Graph Approach For Planning Sustainable Rice Straw Management Networks, Victoria Migo Sumagang Maria, Michael Angelo B. Promentilla

The Philippine Agricultural Scientist

The Philippines produces up to 15.2 Mt of rice straw waste annually. Unmanaged rice straw waste disposal can lead to pollution from open field burning. On the other hand, rice straw agricultural waste can be used sustainably to produce valuable products such as mushrooms, fodder, pellets, or bioenergy, in a rice straw management system. Such systems can be optimized using Process Integration tools so that the raw materials are used efficiently at the maximum profit and with a minimal carbon footprint. The P-graph framework is an efficient Process Integration tool that solves Process Network Synthesis problems. A P-graph finds the …


Boar Sperm Performance In Polystyrene Transport Cool Box Under Various Storage Conditions And Holding Times [Rsearch Note], Santiago T. Peña Jr., Bianca Therese P. Ymas, Mark Edd B. Janier, Heherson A. Luza Sep 2024

Boar Sperm Performance In Polystyrene Transport Cool Box Under Various Storage Conditions And Holding Times [Rsearch Note], Santiago T. Peña Jr., Bianca Therese P. Ymas, Mark Edd B. Janier, Heherson A. Luza

The Philippine Agricultural Scientist

When transporting highly valuable boar semen samples over long distances, it is crucial to ensure that boar semen is stored ideally at approximately 15 – 17°C to minimize the impact of cold shock and oxidative damage on sperm quality. This study evaluated the performance of a commercially available semen and embryo polystyrene transport cool box, BotuFLEX®, in preserving the quality of extended boar semen under different storage conditions and holding times. Boar ejaculates were extended at 1:1 or 1:3 using a commercial mid-term extender, stored in a BotuFLEX® semen cool box, and examined 24 vs. 48 h thereafter (Experiment 1; …


Seal Counting On Our Plages (S.C.O.O.P.), Kaanan Kharwa Sep 2024

Seal Counting On Our Plages (S.C.O.O.P.), Kaanan Kharwa

Master's Theses

The Vertebrate Integrative Physiology (VIP) lab monitors the population of northern elephant seals at the largest mainland breeding colony, located at Piedras Blancas (San Simeon, CA). As the population expands, more human-seal interactions and conflicts over land use occur. The VIP lab's work informs California State Parks and helps with the management of the rookery. Currently, members of the VIP lab fly a drone over the beaches, capture multiple images, and manually count the seals, which takes around 14 to 21 hours of analysis per survey. Machine learning methods such as Convolutional Neural Networks (CNN) and Region-based Convolutional Neural Networks …


In Silico Modelling And Docking Simulation Of Egfr-Targeted Diphtheria Toxin Chimera With Various Targeting Moieties, Muhammad Afif Naufal Bmed, Benedictus Ansell Susanto Bmed, Talitha Dinda Gunawan Bmed, Azhar Ridha Lukman Bmed, Alifa Rahma Rizqina Bmed, Muhammad Misbahul Fuad Bmed Aug 2024

In Silico Modelling And Docking Simulation Of Egfr-Targeted Diphtheria Toxin Chimera With Various Targeting Moieties, Muhammad Afif Naufal Bmed, Benedictus Ansell Susanto Bmed, Talitha Dinda Gunawan Bmed, Azhar Ridha Lukman Bmed, Alifa Rahma Rizqina Bmed, Muhammad Misbahul Fuad Bmed

Indonesian Journal of Medical Chemistry and Bioinformatics

Introduction: Cancer is a major etiology of death worldwide due to high mortality and suboptimal medicine. However, an emerging field, targeted therapy enabled a more selective and effective therapeutic action. This article aims to analyze in-silico the hypothetical targeted therapy agent that is combinations of conjugate consisting of EGFR targeting moieties and diphtheria toxin (DT-390).

Method: Our novel peptide is a conjugate of a novel EGFR targeting peptide and DT-390, forming a chimera. The tertiary structure was predicted using AlphaFold 2.0. The best IDDT scoring and stereochemistry profiles were utilized. The HADDOCK2.4 webserver modelled the docking between our …


The Prospect Of Indonesian Herbal As An Alternative Treatment For Covid-19 Patient: A Literature-Based Study, Hadi Sunaryo, Wahyu Hidayati Aug 2024

The Prospect Of Indonesian Herbal As An Alternative Treatment For Covid-19 Patient: A Literature-Based Study, Hadi Sunaryo, Wahyu Hidayati

Indonesian Journal of Medical Chemistry and Bioinformatics

Coronavirus disease 2019 (COVID-19) is a new disease caused by a novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The disease has several symptoms from mild to severe and could lead to death for comorbidities and the elderly. Therefore, the infections and mortality cases keep growing day by day, moreover many authorities are trying to suppress it by applying several health protocols, including medicines. Several studies were conducted on drug discovery from plants to cure the disease. The article aimed to do a narrative review about the prospect of JAMU becoming an alternative medicine to cure COVID-19 by mapping …


A Step By Step Shoreline Attribute Analysis For Selected Waterbodies In The Gulf Of Mexico To Promote The Use Of Living Shorelines, Christoper Boyd, Xutong Niu, Taylor R. Horn Aug 2024

A Step By Step Shoreline Attribute Analysis For Selected Waterbodies In The Gulf Of Mexico To Promote The Use Of Living Shorelines, Christoper Boyd, Xutong Niu, Taylor R. Horn

The Journal of Extension

Living Shorelines are being promoted by coastal extension professionals as a more resilient nature-based solution to control shoreline erosion. The Virginia Institute of Marine Sciences Living Shorelines Suitability Model was run in selected waterbodies within the Gulf of Mexico.

The locations of the selected water bodies, coastal data sets used, and shoreline protection recommendations generated by the Model are presented. A step-by-step statistical analysis conducted through ArcGIS Pro from these selected coastal shorelines will illustrate how extension professionals with novice GIS experience can use the model output to promote living shorelines to coastal property owners, city managers, and developers.