Engineering Commons^™

Future Meteorological Droughts In The Southeastern Us, Kunal Bhardwaj, C. Prakash Khedun, Abdul A. Khan

Journal of South Carolina Water Resources

The Southeastern U.S., despite its humid climate, experiences recurrent meteorological droughts which impact agricultural, water resources, ecological systems, and the economy and society. Knowledge of future drought conditions can guide adaptation efforts. Here, we evaluate historical and projected droughts using the Standardized Precipitation Index (SPI) and the Standardized Precipitation-Evapotranspiration Index (SPEI) computed from an ensemble of eight bias-corrected Global Climate Models (GCMs) from the Climate Model Intercomparison Phase-6 (CMIP6). The historical performance (1950–2014) of the GCM’s mean was benchmarked against gridded observations from the Climate Research Unit (CRU). Future changes were assessed under 1.5°C, 2.0°C, and 3.0°C global warming levels.We …

Exploration Of Real-Time Power Electronic Simulation On Amd Npu, Shouyu Du

All Theses

The rapid electrification of the automotive and data center sectors has created a critical demand for high-fidelity, real-time simulation of complex power electronic systems. While Hardware- in-the-Loop (HIL) simulation on Field-Programmable Gate Arrays (FPGAs) is the current industry standard, it presents significant challenges regarding development complexity and memory limita- tions. This dissertation investigates the feasibility of utilizing Neural Processing Units (NPUs)— specifically the AMD AI Engine (AIE) XDNA2 architecture—as a novel platform for real-time, deterministic circuit simulation. This study establishes a comprehensive automated modeling framework based on graph theory and Massarini’s method to derive linear state-space representations for arbitrary circuit …

Developing Aero-Floating Treatment Wetland (Aeroftw) Scaffolds: A Non-Plastic Alternative To Conventional Plastic-Based Ftws, Ada C. Montoya Gomez

All Theses

This research was conducted to explore the possibility of constructing floating treatment wetlands (FTWs) without using plastic materials. FTWs are floating platforms that hold plants on the water’s surface, letting roots dangle within the water column, to help remove contaminants from contaminated water, especially in stormwater ponds. Many conventional FTWs are made with plastic components, such as mats and plastic cup containers, which can release microplastics into the environment over time. The goal of this project was to design and test a new type of FTW that does not depend on plastics to support FTW flotation. The study took place …

Bayesian Assembly Tool For Intelligent Digital Twin Selection, Shishir Sharma

All Theses

Digital twins can be used for system performance optimization, health monitoring, predictive maintenance, and investigating system anomalies. A ground vehicle digital twin may be assembled using representations of the subsystem models (tires, suspension system, powertrain, etc.) of different fidelity. Lower fidelity Digital Twins have relatively simpler design and physics, hence are generally computationally less expensive, but may not represent the physical system accurately. On the contrary, higher fidelity Digital Twins are generally more precise in their ability to represent the physical system, but due to complexity, are usually computationally more demanding. This thesis describes the application of Bayesian Classification within …

Implementation Of A Local Llm Serving System For Agentic Ai, Zhiheng Ni

All Theses

This thesis presents a system that allows large AI models to run directly on personal devices instead of relying on cloud servers. Recent advances in artificial intelligence, especially large language models (LLMs), have made it possible to build powerful applications such as chatbots, coding assistants, and intelligent agents. However, most of these systems run in the cloud, which raises concerns about privacy, latency, and cost.

To address these issues, this work develops a local AI serving system that runs efficiently on a specialized hardware component called a Neural Processing Unit (NPU). The system provides a unified interface that supports multiple …

Quantifying The Value Of Adaptability: Bridging Real Options Analysis And Adaptable Building Design, Miranda Grice

All Dissertations

As the demands of the built environment continually evolve, buildings are expected to meet changing occupancy needs, or otherwise they become obsolete. Despite positive research on the benefits of adaptable building design, there is a knowledge gap regarding the long-term economic benefits of these designs. Practical methods are needed to determine if premium costs associated with adaptable designs are justified by the economic benefits inherent in adaptability. Therefore, this dissertation provides a discussion on the application of the financial theory of options analysis to the design of adaptable buildings. Additionally, a model and accompanying tool are presented as a solution …

Domain-Specific Design On Fpga And Npu For Scientific Computing And On-Device Llm Inference, Miaoxiang Yu

All Dissertations

High-performance computing (HPC) is changing rapidly as scientific simulations and large language model (LLM) workloads push the need for higher performance under tight power and memory constraints. Conventional platforms such as CPUs and GPUs accelerate computation through instruction-driven parallelism, relying on multithreading, SIMD, and SIMT execution, but increasingly encounter scalability limits imposed by the power and memory walls. In contrast, Field-Programmable Gate Arrays (FPGAs) and Neural Processing Units (NPUs) offer a high-efficiency alternative through dataflow-oriented architectures that exploit deep pipelining and customized memory hierarchies to reduce data movement. However, the performance potential of these spatial accelerators remains largely unrealized when …

Physical And Optical Properties Of The Germanium-Arsenic-Selenium Glass Forming Region For Precision Glass Molding And Infrared Optics, Peter F. Wachtel Ii

All Dissertations

The growth and advancement of infrared optical systems for thermal imaging, multi-band imaging, hyperspectral imaging, medical diagnostics, and chemical sensing are pushing the material science community to better understand existing materials while also developing new materials. Additionally, the thermal imaging market continues to grow, and system designers are continually being asked to reduce size, weight, and power while reducing costs (SWaP-c). Market growth has shifted optics manufacturing towards higher volume processes such as precision glass molding, but this does require most materials to be recharacterized due to property changes resulting from the process. Affecting the SWaP-c requirements, manufacturing tolerances are …

Effects Of A Passive Assistive Hamstring Device On Overground Running Kinematics And Hamstring Activation., Quinn Castner

All Theses

Hamstring strain injuries are among the most common and recurring injuries in sports, occurring most often during the terminal swing phase of gait. Despite progress in rehabilitation, the incidence of injury has only increased, suggesting a need for a novel intervention. We designed a passive, assistive, wearable device with two specific criteria in mind: to offload the hamstrings during running, and do so without hindering normal kinematic patterns. The device consists of an adjustable elastic band anchored proximally at the waist and distally just above the ankle joint center. It stretches and shortens with the hamstrings, providing passive hip extension …

Robustness Of Vision Language Models For Pedestrian Detection Tasks, Ostonya K. Thomas

All Theses

Autonomous vehicle (AV) systems typically employ modular systems in which discrete components handle separate tasks such as perception, computation, and path planning. While flexible, this approach allows errors to propagate and compound across the pipeline, and many AI systems offer little transparency into their internal decision-making. Such limitations are particularly concerning in safety-critical domains where failures can carry lethal consequences. Vision Language Models (VLMs) have emerged as a promising alternative because they support end-to-end implementations that bypass compounding error risks and provide natural language explanations of their outputs. Despite these advantages, prior research has demonstrated that both computer vision systems …

Enhanced Situational Awareness Of Solar Pv Plants For Near Real-Time Planning And Operation In Modern Power Systems, Michael A. Walters

All Theses

Solar photovoltaic (PV) plant development and utilization is increasing worldwide but remains intrinsically challenged by its large dependence on highly variable weather conditions and operating states. This paper presents a framework to leverage three new situational awareness indices (SAIs), namely: weather condition index (WCI) to gauge operational performance based on environmental states, operational complexity index (OCI) to indicate the severity of power generation reductions, and photovoltaic generation index (PVGI) to provide a final determination of the impact on power generation and to bolster situational awareness in planning and operational contexts for solar PV plants. This is accomplished by exploiting the …

Versatile Exoskeleton Control Paradigms For Agile Human Locomotion: Task-Agnostic And Stability-Augmented Assistance, Miao Yu

All Dissertations

Lower-limb exoskeletons have shown great potential for assisting human locomotion, but designing controllers that provide assistance across diverse locomotor tasks and under external perturbations remains a major challenge. Many existing controllers for steady-state walking rely on pre-defined reference trajectories, which constrain voluntary human motion and limit adaptability across tasks. Moreover, they usually assume stable walking, while their performance under unstable conditions remains largely unexplored. In addition, existing gait stability augmentation controllers are often reactive rather than proactive to unstable conditions. In this dissertation, we propose control frameworks that preserve voluntary human motion while addressing two major challenges: providing task-agnostic assistance …

Engineering Silicone Magnetic Fluids For Localized Radiation Attenuation During Ocular Melanoma Brachytherapy, Zachary L. Caprow

All Dissertations

Ocular melanoma is commonly treated using plaque brachytherapy; however, radiation-induced damage to healthy ocular tissues frequently results in partial or complete vision loss. This work investigates the development of an injectable, magnetically responsive silicone magnetic fluid designed to localize adjacent to the tumor and attenuate low-energy gamma radiation during treatment.

The material system consists of iron oxide nanoparticles surface-functionalized with a siloxane polymer, in which the nanoparticles provide magnetic responsiveness and radiation attenuation, while the polymer coating ensures colloidal stability, injectability, and biocompatibility. A one-pot synthetic approach was developed wherein a functionalized siloxane polymer containing iron-affinitive groups was reacted with …

Investigation Into The Effects Of Moderate-Dose Radiation On Ligament Biomechanics, Andrew Landefeld

All Theses

Recent advances in arthritis treatment pin ionizing X-ray radiation as a useful tool in reducing joint pain and immune response. However, due to a lack of fundamental research in the effects of low-dose ionizing radiation on tendon and ligament biomechanics, the safety of these studies is rather unknown. While most related studies investigated cellular response to low dose treatment, surrounding tissue physiology is left out of the picture. Additionally, moderate range doses of irradiation are rarely studied, as most uses of radiation on tendons and ligaments are for sterilization of cadaver tendons for allografts. This study provides a preliminary investigation …

Feasibility Study Of Transitioning From Thick Plates (0.250”) Mounted On 30-Point Pvc Carriers To Thinner Plate Technologies Mounted On Recyclable Foam And Pet (0.155”) For Post-Print Corrugated, Nathaniel J. Poole

All Theses

In the United States, the most common press configuration for brown-box printing is a 0.280” undercut press. These press configurations have long relied on thick 0.250” plates mounted on 0.030” PVC sheets to print onto corrugated substrates. Each year, around twenty million pounds of waste are produced by the printing industry, through paper waste, plate waste, among other materials. One large factor of that waste is flexographic plate waste, which either ends its life in a landfill or is repurposed into other products. This study establishes a comparison between traditionally used 0.250” plates on 30pt PVC versus 0.155” plates mounted …

Robust Hardware Trojan Detection Leveraging Dual‑Domain Features And Stacked Ensemble Learning, Sefatun-Noor Puspa

All Theses

In Cyber-physical systems rely on sensors, communication, and computing, all powered by integrated circuits (ICs). These ICs are vulnerable to malicious hardware attacks, with hardware Trojans being one of the stealthiest threats. Trojans are malicious implants in the circuitry, which are often inserted during design or fabrication stages. This stealthy addition remains dormant until triggered and might cause functional disruptions or sensitive information leakage once triggered. Traditional IC validation methods, such as functional testing and logic analysis, usually fail to capture these subtle anomalies because hardware Trojans are intentionally designed to mimic normal circuit behavior. They often remain dormant under …

Laser-Induced Acoustic Signal Generation, Resonance Characterization, And Optical Sensing In Metallic Plates, Xinghang Zhao

All Theses

This thesis investigates laser-induced acoustic signal generation, resonance characterization, and optical sensing in metallic plates as a foundational study for damage-sensitive inspection. Rather than presenting a complete defect-detection system, the work focuses on how measurable acoustic responses can be generated, amplified, and interpreted in a controlled laboratory setting. Experiments showed that pulsed-laser excitation can produce strong and repeatable acoustic responses in metallic structures. Repetition-rate sweeping identified narrow resonant responses, including a cantilever resonance at 57.862 kHz and a maximum circular-disk response at an FFT frequency of 48.8 kHz with a laser repetition rate of about 49.1 kHz. High-Q resonances exceeding …

Field Testing Of Retrofits To Improve The Structural Behavior Of South Carolina Flat-Slab Bridges, Jacob Bowers

All Theses

The South Carolina Department of Transportation manages approximately 2,300 “flat-slab” bridges statewide, with an average age of 58 years, according to the National Bridge Inventory (NBI 2024). Many of these structures were originally designed for H10 or H15 truck loadings, which are significantly below current design standards. As a result, numerous bridges have been load-posted, restricting freight movement, emergency response, and local connectivity. While full replacement provides a long-term solution, it is often cost-prohibitive and disruptive. Accordingly, the South Carolina Department of Transportation is seeking cost-effective retrofit strategies that improve performance and extend the service life of these bridges. Implementing …

Estimation Of The Mechanical Properties Of South Carolina Timber Piles Using Non-Destructive Evaluation Methods And Experimentally-Informed Models, Aashish Sapkota

All Theses

South Carolina has about 2,600 bridges that are supported by nearly 75,000 timber piles. They are increasingly vulnerable to biological decay, cracking and impact damages after decades of service. Current inspection methods used by the South Carolina Department of Transportation (SCDOT), such as hammer sounding and awl probing, are labor-intensive and expensive. This study investigated non-destructive evaluation (NDE) methods, including micro-resistance drilling and stress wave timing, as alternatives for assessing timber pile condition.

Ten timber piles were collected from two South Carolina bridges, and their above-grade portions were cut into 40 specimens approximately 13 to 15 inches long. Specimens were …

Neural-Network-Based Modeling Of Grid-Forming Inverters, Jacob D. Levesque

All Theses

Renewable energy production has grown significantly in recent years and continues to expand, resulting in an increasing number of inverter-based resources (IBRs) in the grid. As the number of IBRs in the grid continues to grow, grid-forming (GFM) inverters are becoming increasingly popular due to their ability to regulate voltage and frequency, providing increased grid stability and enabling islanding. As GFM inverters become more widely used in power systems, accurate and efficient models of their behavior are needed for system design purposes.

Emerging advances in neural networks have led to research on computationally efficient neural-network-based (NN-based) modeling approaches for inverters. …

Multimodal Aerial Image-Based Ground Object Detection And Classification Using Yolo, Erik Nielsen

All Theses

Object detection in unmanned aerial vehicles (UAVs) present a unique challenge due to small object sizes, varying viewpoints, and changing environmental conditions. These challenges are exacerbated when operating during daytime and nighttime scenarios where illumination differences can heavily impact detection performance. This work is motivated by military object detection applications where the ability to reliably identify small objects such as landmines or unexploded ordnance from aerial imagery presents a critical safety need and a significant technical challenge. In this paper, we investigate object detection using both visible (RGB) and infrared (IR) imagery to improve robustness and reliability across diverse operating …

The Impact Of Dipeptides On Product Quality In Chinese Hamster Ovary Cells, Louise C. Herman

All Theses

Biopharmaceuticals are medicines produced in cells which are used to treat diseases such as cancer. Monoclonal antibodies (mAbs) represent the majority of approved biotherapeutics. MAbs are mostly produce using Chinese hamster ovary (CHO) cells. CHO cells are favored for resiliency, scalability, and established safety, and are considered the “workhorse” organism for biopharmaceuticals.  Amino acids are a key component of cell culture media, however several amino acids have solubility limits, such as cysteine, cystine, and tyrosine.  At neutral pH, these amino acids are poorly soluble.  However, dipeptides, such as N,N'-di-L-Alanyl-L-Cystine (ACCA) have been reported to increase cysteine and cystine availability. Further, …

Fluorescence-Based Quantification Of Hepatic Ldl Uptake And Donor Hepatocyte Engraftment Using Atto 700–Labeled Ldl, Victor Agustin Cortes Flores

All Theses

Familial hypercholesterolemia (FH) is an inherited disorder characterized by elevated low-density lipoprotein cholesterol (LDL-C) that increases the risk of premature atherosclerotic cardiovascular disease. In severe FH, including low-density lipoprotein receptor (LDLR), hepatic LDL clearance is profoundly impaired and many lipid lowering treatment strategies have limited effectiveness. Current advances in ex vivo CRISPR–Cas9 hepatocyte gene editing in vivo and ex vivo approaches for treatment of FH are under development.

However, a central barrier to translation is the ability to quantitatively measure the percentage of healthy gen edited hepatocytes in the liver while simultaneously assessing functional hepatic LDL handling. This thesis establishes …

Increasing The Number Of Injections Per Cycle In A Gasoline Compression Ignition Strategy: An Experimental Study, Joshua Murray

All Theses

Gasoline Compression Ignition (GCI) is an advanced compression ignition strategy which utilizes the high octane number of gasoline to improve diesel soot and NOx emissions by enabling partially premixed injections of fuel. GCI work in the literature typically uses single, double, or triple injection strategies, with higher numbers of injections noted for their ability to achieve low MPRRs, improved soot and NOx emissions, and higher efficiency. Thus, this study extends the literature by evaluating quadruple and quintuple injection strategies for continued improvement in engine efficiency and emissions.

The experiments in this work are conducted on a heavy-duty Detroit Diesel DD13 …

Exercise-Induced Muscle Damage As A Model For Exploring The Effects Of Pain On Gait, Sydney Savage

All Theses

Persistent gait asymmetry following anterior cruciate ligament reconstruction (ACLR) is a recognized contributor to post-traumatic knee osteoarthritis, yet the independent role of pain in driving altered movement patterns remains poorly understood due to confounding factors inherent to clinical populations. This study used exercise-induced muscle damage (EIMD) as a controlled experimental model to isolate the effects of musculoskeletal pain on gait, independent of kinesiophobia, structural damage, and proprioceptive disruption. Eighteen healthy adults underwent unilateral eccentric calf-raise protocols to induce delayed onset muscle soreness (DOMS), with gait assessed at baseline, 48 hours, and 168 hours post-exercise using bilateral inertial measurement units. Outcomes …

Design And Development Of A Perfusable Hydrogel Platform With Bioprinted Human-Endothelialized Microvascular Channels, Calvin A. Chernyatinskiy

All Theses

We developed an integrated bioprinting and perfusion platform to generate vascularized hydrogel constructs that support perfusable microchannel networks. Multiple hydrogel formulations, sacrificial ink systems, device geometries, and perfusion conditions were systematically evaluated to optimize print fidelity, mechanical stability, and cellular compatibility. Internally gelling alginate–calcium carbonate hydrogels were identified as a robust matrix, providing tunable gelation kinetics and structural stability during embedded printing. In parallel, Pluronic F-127 fugitive ink enabled reliable fabrication of continuous hollow channels due to its shear-thinning behavior and efficient post-print removal.

The finalized platform integrates stereolithographically fabricated perfusion chambers with extrusion-based bioprinting to produce three-dimensional, perfusable vascular …

Development Of Low-Cost Triaxial Force Sensor For Measurement Of Human-Exoskeleton Interaction Forces, Hamdan Khan Sarvathullah

All Theses

Contemporary research suggests that shear force is a major contributor to discomfort and pressure injury. However, the variation of shear forces during human-exoskeleton interaction dynamics is a highly unexplored field. The high cost of commercial triaxial force sensors may be a major factor in the notable lack of research in this field. Therefore, in this paper, we present a low-cost, 3D-printed triaxial force sensor designed specifically to measure the triaxial interaction forces between an exoskeleton and its user. The triaxial force sensor uses Carbon-Black/Silicone Rubber (CB/SR) strings to measure shear forces, whereas the normal force is measured with a Force …

Enhancing Reliable Performance Of Microgrids With Autonomous Control Of Distributed Energy Resources, Sahand Liasi

All Dissertations

This dissertation presents a comprehensive investigation into enhancing the reliability, efficiency, and autonomous operation of modern power networks through advanced microgrid integration and control strategies. The research addresses critical challenges across three interconnected domains: microgrid control, thermodynamic modeling of heat recovery system (HRS), and optimal distribution network reliability.

In the realm of microgrid control, this work introduces novel methodologies for grid forming inverter-based resources (IBRs). A significant contribution is the development and validation of an "Auto Frequency Change" controller, which drastically reduces microgrid synchronization time with the main grid from several minutes to approximately four seconds, with theoretical potential for …

Development And Validation Of The Ampere Scale: Measuring Adaptive And Maladaptive Perfectionism In Engineering Students, Haleh B. Brotherton

All Dissertations

Perfectionism refers to the inclination to set very high expectations for oneself, which can at times encourage personal development and at other times lead to stress and a sense of pressure. Perfectionism is widely observed among engineering students; however, instruments that distinguish adaptive striving from concern-driven tendencies in the engineering context remain limited. My study is based on the development and validation of the AMPERE (Adaptive and Maladaptive Perfectionism in Engineering) scale through a three-phase process: (I) expert review with two domain experts to establish content validity; (II) cognitive interviews with seven undergraduates to refine wording and interpretability; and (III) …

Generative Ai Of Breast Cancer Progression In Gene Expression Space, Xusheng Ai

All Dissertations

Breast cancer is one of the most common and deadly cancers in the world. Although doctors can use gene activity data to better understand different types of breast cancer, it is still difficult to identify the most important genes and to track how the disease changes over time. This is partly because gene data are very large and complex.

This dissertation develops a computer-based framework to study breast cancer using gene expression data. The work focuses on three goals: creating realistic synthetic gene data, identifying important genes linked to cancer, and modeling how breast cancer changes from normal tissue to …