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Articles 1 - 30 of 78123
Full-Text Articles in Engineering
Elevate Hardcase, Caleb J. Bailey, Colby M. Cordoba, Marissa Mccleod, Shaan Sandhu
Elevate Hardcase, Caleb J. Bailey, Colby M. Cordoba, Marissa Mccleod, Shaan Sandhu
Mechanical Engineering
The Elevate Hardcase project developed a portable mechanical elevation system that allows users to access rugged hard cases at a comfortable working height without needing a separate table or placing the case on uneven ground. The design focuses on improving ergonomics, portability, stability, and quick setup for users in field environments such as photography, hunting, and maintenance. Through customer research, concept development, prototyping, analysis, and testing, the final system was designed to support a loaded hard case, provide height adjustability, remain stable on uneven terrain, and be deployed by a single user in under five minutes. The final prototype demonstrates …
Design And Production Of A Carbon Fiber Longboard, John R. Beebe, Jacob Williams, Julia Stradinger, Vince Fitchtel, Jordan Cochran
Design And Production Of A Carbon Fiber Longboard, John R. Beebe, Jacob Williams, Julia Stradinger, Vince Fitchtel, Jordan Cochran
Honors Theses
This thesis contains an overview of the design, prototyping, and manufacturing of a carbon fiber long board. The purpose of this capstone was to create a viable product for the real-world market and then determine how to manufacture it at scale with sustainable financial practices. In order to accomplish this task, engineering, accounting, and manufacturing challenges had to be overcome throughout all stages. The production process involved the carbon fiber layup, baking, water jet cutting, and assembly of the carbon fiber longboard. In order to optimize this process, continuous improvement and lean manufacturing problem solving techniques were applied. After a …
What Types Of Uncertainty Emerge In Instructional Aviation Incidents?, Abigail Henson
What Types Of Uncertainty Emerge In Instructional Aviation Incidents?, Abigail Henson
Mechanical Engineering Undergraduate Honors Theses
This study utilized narrative reports from the National Aeronautics and Space Administration (NASA) Aviation Safety Reporting System (ASRS) database to examine the types of uncertainty present in near-miss instructional aviation incidents occurring within the United States between 2015 and 2025. The final dataset consisted of 86 reports, with each report containing a set of narrative accounts from both the student pilot and the flight instructor operating under Part 91 regulations. Each instructional event was classified using a combined framework incorporating uncertainty categorizations and the Human Factors Analysis and Classification System (HFACS). Results indicate that epistemological uncertainty was the most common …
A Maximum Energy Release Rate Computational Framework For Fatigue Crack Trajectory And Life Prediction Under Mixed-Mode Proportional And Nonproportional Loading, Nahla Helmy Matar
A Maximum Energy Release Rate Computational Framework For Fatigue Crack Trajectory And Life Prediction Under Mixed-Mode Proportional And Nonproportional Loading, Nahla Helmy Matar
Theses and Dissertations
The problem of mixed-mode fatigue crack growth has been a persistent research challenge. The determination of fatigue crack propagation direction directly impacts the safety and integrity of components and structures, making it crucial in various industrial applications, including welded drilling pipes, aerospace, and automotive engineering. Unlike uniaxial loading, mixed-mode cracks tend to change direction frequently (kinking), and nonproportional loading adds to the complexity of the problem. This research aims to estimate the crack propagation direction and fatigue crack life in linear elastic materials subjected to mixed-mode (I+II) loading conditions under proportional or non-proportional cyclic loading. Numerical software was developed based …
Simulation-Based Assessment Of Operational And Retrofit Solutions For Effluent Compliance Of A Capacity-Limited Oxidation Ditch Wwtp, Ahmed Sameh Harash
Simulation-Based Assessment Of Operational And Retrofit Solutions For Effluent Compliance Of A Capacity-Limited Oxidation Ditch Wwtp, Ahmed Sameh Harash
Theses and Dissertations
Oxidation-ditch wastewater treatment plants (WWTPs) across Egypt's Nile Delta are increasingly carrying hydraulic and organic loads beyond what they were designed for. This work can be considered pioneering as this work compared operational and structural retrofit alternatives for such a plant within a single verified simulation framework. The present study fills that gap by building a digital twin of the Qaha WWTP, a dual-train Carrousel oxidation ditch in Qalyubia Governorate, calibrated to a baseline flow of 7,420 m³/day in the SUMO24 platform (a third-generation, open-source wastewater treatment process simulation software) using the SUMO2c biokinetic model (a simplified variant of Activated …
Dynamic Baseline Schedule Updates Using Digital Twinning: A Case Study On Aluminum Formwork Construction, Ahmed Hamdi Sweilam
Dynamic Baseline Schedule Updates Using Digital Twinning: A Case Study On Aluminum Formwork Construction, Ahmed Hamdi Sweilam
Theses and Dissertations
Repetitive high-rise construction using aluminum formwork couples consecutive floor cycles through a reused panel set and a floor-level inspection and pour barrier, so productivity loss compounds upward rather than being absorbed locally. The baseline schedule is nevertheless fixed before execution and is not revised as evidence of realized productivity accumulates. This thesis develops a simulation-based digital twin that updates the baseline from observed as-built durations and acts on its own forecast. A discrete-event simulation of a ten-story residential tower is built in AnyLogic® and verified analytically at 180.00 hours per floor. After each completed floor the twin infers activity productivity …
Sustainable – Low-Cost - Upgrade Of Activated Sludge Process For Nitrogen And Phosphorus (N&P) Removal From Wastewater, Abanoub N. Basta
Sustainable – Low-Cost - Upgrade Of Activated Sludge Process For Nitrogen And Phosphorus (N&P) Removal From Wastewater, Abanoub N. Basta
Theses and Dissertations
Many municipal wastewater treatment plants (WWTPs) in developing countries were designed primarily for organic matter and suspended solids removal and therefore face increasing difficulty in meeting modern nitrogen (N) and phosphorus (P) discharge requirements. Conventional biological nutrient removal upgrades commonly require additional reactor volume, recirculation systems, aeration energy, and capital investment. Accordingly, sustainable retrofit strategies that improve nutrient removal within existing treatment footprints are increasingly needed, particularly in water-scarce and land-constrained regions.
This study investigated the integration of water hyacinth (Eichhornia crassipes) into the aeration stage of an activated sludge process as a hybrid nature-based enhancement for nitrogen and phosphorus …
A Comparative Study: Force Majeure And The Theory Of Unforeseen Circumstances Across Different Jurisdictions In The Middle East, Omar Hamed Sawan
A Comparative Study: Force Majeure And The Theory Of Unforeseen Circumstances Across Different Jurisdictions In The Middle East, Omar Hamed Sawan
Theses and Dissertations
The motivation behind this study stems from recent global disruption events that impact construction projects worldwide. These events vary across a wide spectrum, whether they are political events such as the Russo-Ukraine war or the war in the Middle East, economic events such as inflation or currency devaluations; or environmental events such as climate change and the emergence of public health crises like the Covid-19 pandemic. These series of events underscore the growing importance of understanding how the different legal frameworks address unforeseeable events in the construction industry. In this context, force majeure and the theory of unforeseen circumstances (also …
Deep Brain Stimulation In Early-Stage Alzheimer's Disease: A Systematic Review Of Neuropsychological Outcomes, Nora Huey
Doctoral Dissertations
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory impairment, and disruption of neural networks involved in cognitive functioning. Although existing treatments may provide symptomatic benefit, there remains a need for interventions capable of slowing or stabilizing disease progression. Deep brain stimulation (DBS) has emerged as a potential neuromodulatory intervention for early-stage AD through stimulation of memory- and cognition-related neural circuitry. This dissertation employed a systematic review research methodology to examine teh neuropsychological and neurobiological outcomes associated with DBS targeting the fornix (DBS-f) and nucleus basalis of Meynert (DBS-NBM) in individuals with early-stage AD over 12–24 …
Adaptive Active Snore Noise Control Using Microphone And Loudspeaker Arrays, Nathan Walker
Adaptive Active Snore Noise Control Using Microphone And Loudspeaker Arrays, Nathan Walker
All Graduate Theses and Dissertations, Fall 2023 to Present
Snoring can wreck a good night’s sleep, not just for the snorer but for their partner, and over time it can strain relationships. Common fixes like CPAP machines, nasal strips, and earplugs either have to be worn or don’t do much against the deep, low-pitched rumble that makes snoring so hard to ignore.
This research explores a different approach, a device that doesn’t need to be worn at all. It uses a small set of microphones to listen to the snoring and a set of speakers to play back carefully timed anti-snore noise, which is sound designed to cancel out …
Enhancing Agricultural Sustainability Under Climate Change: A Multi-Scale Framework Integrating Climate Extremes, Resource Efficiency, And Data-Driven Modeling, Shahryar Fazli
Computational and Data Sciences (PhD) Dissertations
Agricultural systems are increasingly challenged by climate variability, where shifting temperature regimes, hydrological variability, and the rising frequency of compound and cascading extremes threaten global food security and resource sustainability. Addressing these challenges requires integrated frameworks that bridge biophysical monitoring, predictive modeling, and adaptive decision-making. This dissertation develops a data-driven, multi-scale framework to quantify and enhance agricultural resilience by integrating remote sensing, climate analytics, and machine learning across the United States, with a focus on California and the Western U.S.
First, hyperspectral and thermal remote sensing data from EMIT and OpenET are integrated to characterize crop nitrogen–water interactions and assess …
Power At Sea Develop Phase, Jake Lauer, Isabella Heinemann, Bailey Gargasz, Zachery Boyer
Power At Sea Develop Phase, Jake Lauer, Isabella Heinemann, Bailey Gargasz, Zachery Boyer
Mechanical Engineering
This project develops a renewable, wave-powered charging system designed to extend the mission duration of Autonomous Underwater Vehicles by eliminating the need for frequent manual battery replacement. Building upon a prior oscillating water column prototype from the CONCEPT phase, the team redesigned and tested an improved system capable of converting wave-induced air motion into electrical power using a Wells turbine. Key enhancements include doubling the column diameter to increase displaced air volume, integrating a flared inlet and bi-directional nozzle to improve airflow, and selecting corrosion-resistant materials suitable for long-term deployment in marine environments. Multiple prototypes were constructed and evaluated through …
Cascaded Pid Control Of A Passive Bio-Inspired Rotating Empennage Aircraft, Zachary T. Jenkins
Cascaded Pid Control Of A Passive Bio-Inspired Rotating Empennage Aircraft, Zachary T. Jenkins
All Graduate Theses and Dissertations, Fall 2023 to Present
This thesis presents an autopilot for a Bio-Inspired Rotating Empennage (BIRE) aircraft. Most airplanes control yaw using a vertical stabilizer and a moving rudder, a design that has stayed essentially unchanged for nearly a century but adds weight, drag, and surface area to the aircraft. The BIRE removes the vertical tail entirely and instead allows the horizontal tail to rotate about the body x-axis of the airplane; tilting the horizontal tail produces a yaw force, doing the job of a rudder. This thesis first develops a controller for the BIRE where the empennage angle is commanded directly, then extends …
Physics-Data-Hybrid Modeling And Control For Vtol Aircraft, Samantha Dawn Burton
Physics-Data-Hybrid Modeling And Control For Vtol Aircraft, Samantha Dawn Burton
All Graduate Theses and Dissertations, Fall 2023 to Present
Vertical takeoff and landing (VTOL) aircraft are hybrid aircraft having both a helicopter flight mode and a fixed-wing plane flight mode. The objective of this dissertation is to examine and evaluate a new approach, physics-data-hybrid (PDH), for VTOL aircraft modeling and control. The PDH approach combines traditional, physics-based methods (Newtonian mechanics) with data driven methods (a machine learning technique called a Koopman operator model) to create an efficient and accurate modeling and control framework—mitigating the disadvantages of the purely physics-based and purely data-driven methods. The PDH approach is used to model scenarios when the VTOL aircraft transitions between helicopter mode …
Flight System Development For A Bio-Inspired Rotating Empennage Experimental Unmanned Aerial Vehicle, Ashton Gilbert
Flight System Development For A Bio-Inspired Rotating Empennage Experimental Unmanned Aerial Vehicle, Ashton Gilbert
All Graduate Theses and Dissertations, Fall 2023 to Present
Unmanned aerial systems, commonly known as drones, are increasingly used for research, environmental monitoring, and testing new aircraft concepts. Many commercially available drone flight controllers work well for standard aircraft designs, but they can be difficult to adapt for experimental vehicles that use unconventional control methods or require detailed monitoring during testing. This creates challenges for researchers who need flexible and reliable tools to safely evaluate new flight technologies. This work presents the development of a custom drone flight control system designed specifically for experimental research. The system integrates custom electronics and software that allow researchers to easily modify control …
Psychometric Evaluation And Cognitive Correlates Of The Tactile Mental Cutting Test: Investigating Reliability, Validity, Gender Differences In Spatial Ability, Executive Function And Social Emotional Competence Among Native American Elementary Students, Sujata Basnet
All Graduate Theses and Dissertations, Fall 2023 to Present
Spatial ability-the ability to understand, visualize, and mentally manipulate shapes and objects-is important for learning in science, technology, engineering, and mathematics (STEM). However, many traditional spatial ability tests rely heavily on drawings and other visual representations and have often been developed and evaluated with populations that do not adequately represent culturally diverse students. As a result, there is a need for assessment approaches that are developmentally appropriate, engaging, and potentially more inclusive for young learners. The Tactile Mental Cutting Test (TMCT) provides one such approach by allowing students to explore three-dimensional objects through touch and physical manipulation while solving spatial …
Extending Geometric Acoustic Ray Tracing To Multi-Room Environments: A Case Study On Gunshot Sound Transmission Between Adjacent Rooms, Tyler Ton
Theses and Dissertations
Accurate localization of gunshots in multi-room building environments remains a challenging problem in acoustic forensics and public safety applications. Existing approaches model sound propagation within a single room, neglecting the transmission of acoustic energy through walls and other building materials. This thesis presents a study on modeling multi-room gunshot acoustic transmission, combining geometric ray tracing with structural acoustic transmission-loss modeling to generate impulse responses for two horizontally adjacent rooms separated by a shared wall, providing a foundation for future inter-room gunshot localization work. The proposed system uses GSound-SIR, a geometric acoustics engine, to simulate sound propagation in both of the …
A Data-Driven Koopman Framework For Station-Keeping On Near Rectilinear Halo Orbit, Anusha Sharma Malladi
A Data-Driven Koopman Framework For Station-Keeping On Near Rectilinear Halo Orbit, Anusha Sharma Malladi
Theses and Dissertations
Cislunar missions have gained significant attention in recent decades, motivating the need for efficient modeling and reliable control. In this work a Koopman operator based framework is developed for approximating the error dynamics around a reference Near Rectilinear Halo Orbit (NRHO) in the Earth-Moon Circular Restricted Three-Body Problem (CR3BP). A decoder free neural network is used to learn a lifted linear representation of the nonlinear CR3BP dynamics and a residual based approach is used to identify the corresponding control input matrix. The model is then implemented in a receding-horizon target point controller and compared with uncontrolled propagation and a State …
Comparative Performance Of Physiological Vital-Sign Forecasting Under Random And Patient-Wise Splitting Using Deep Learning, Lavanya Vasavi Chittem Reddy
Comparative Performance Of Physiological Vital-Sign Forecasting Under Random And Patient-Wise Splitting Using Deep Learning, Lavanya Vasavi Chittem Reddy
Theses and Dissertations
Physiological vital-sign forecasting estimates future measurements based on recent temporal patterns and can support analysis of continuously recorded monitoring data. This study comparatively evaluated deep feedforward, recurrent, bidirectional recurrent, long short-term memory, and bidirectional long short-term memory architectures for one-step-ahead forecasting of peripheral oxygen saturation, heart rate, and pulse rate. Each model received consecutive observations of peripheral oxygen saturation, heart rate, pulse rate, respiratory rate, and age, while separate single-output models predicted the next value of the selected target.
Random and patient-wise data splitting were compared using identical input definitions, preprocessing procedures, model architectures, and training hyperparameters. The strongest architecture …
Developing Imitation Learning Policies By Exploring Diffusion Framework For Quadcopters, Likith Swamireddy
Developing Imitation Learning Policies By Exploring Diffusion Framework For Quadcopters, Likith Swamireddy
Theses and Dissertations
Imitation learning offers a promising approach in developing near-optimal onboard policies for nonlinear systems, by learning from computationally expensive trajectory planners during offline training. Existing State-of-the-art methods commonly learn deterministic mappings from observations to actions by training fast neural networks to mimic the expert demonstrations, which can limit their ability to capture the action distribution, when the policy is trained on multiple possible expert commands to reach the same target, and this may lead to unsafe scenarios in the obstacle environments. To address these challenges, this study explores Diffusion Models (DMs) as a feedback controller for quadcopters that learns the …
Scalable Quality Assessment Of Ground Motion Records Via Interpretable Deep Learning Architectures, Ali Montazeri Namin
Scalable Quality Assessment Of Ground Motion Records Via Interpretable Deep Learning Architectures, Ali Montazeri Namin
All Graduate Theses and Dissertations, Fall 2023 to Present
Earthquake engineers rely on accurate recordings of ground shaking to design safe and resilient buildings. However, sorting through thousands of these recordings to find the reliable ones and throwing out those ruined by sensor errors or background noise is traditionally done by hand. Because modern seismic networks collect massive amounts of earthquake data every day, this manual checking process is much too slow. To fix this, researchers are turning to artificial intelligence to automatically check the quality of these recordings.
While artificial intelligence offers a fast solution, there are limitations. These computer models can become massive and expensive to run, …
Engineering, Processing, And Evaluation Of Alternative Solid-Phase Carbon Media For Passive Self-Regulatory Denitrification (Psrd), Chinedu James Chiama
Engineering, Processing, And Evaluation Of Alternative Solid-Phase Carbon Media For Passive Self-Regulatory Denitrification (Psrd), Chinedu James Chiama
LSU Doctoral Dissertations
Biological denitrification is an effective and cost-efficient approach for nitrate removal; however, conventional processes often rely on liquid carbon sources such as methanol or acetate that require precise dosing and monitoring. Solid-phase denitrification (SPD) using polyhydroxybutyrate (PHB) provides a self-regulating alternative, but its high cost limits widespread application. This dissertation investigated strategies to develop lower-cost solid carbon media and simplify SPD operation for recirculating aquaculture systems (RAS). PHB/cellulose (PHBC) blends containing 20–40% cellulose were first evaluated against pure PHB based on nitrate conversion, carbon release, substrate consumption, and denitrification cost. PHBC60:40 and PHBC70:30 achieved the highest apparent peak nitrate conversion …
Willingness To Pilot Under Varying Weather And Tower System Conditions: Mediating Effects Of Risk, Nathan Royal Schultz
Willingness To Pilot Under Varying Weather And Tower System Conditions: Mediating Effects Of Risk, Nathan Royal Schultz
Doctoral Dissertations and Master's Theses
The implementation of Remote Tower Systems (RTS) within the National Airspace System (NAS) offers potential improvements in operational efficiency, cost-effectiveness, and scalability; however, its success depends on pilots' willingness to operate in such environments. This study examined the effects of tower system type (RTS vs. Traditional Tower Systems [TTS]) and weather conditions (visual meteorological conditions [VMC], marginal visual meteorological conditions [MVMC], and instrument meteorological conditions [IMC]) on pilots’ willingness to pilot (WTP), while also evaluating the mediating role of perceived risk (PR). Grounded in Paul Slovic’s Risk Perception Theory (RPT), this research employed a quantitative experimental design using a factorial …
Domain Knowledge-Informed Machine Learning Model To Study Weather-Induced Flight Delays, Gurvir Bawa
Domain Knowledge-Informed Machine Learning Model To Study Weather-Induced Flight Delays, Gurvir Bawa
Doctoral Dissertations and Master's Theses
Weather-induced Traffic Management Initiatives (TMIs) occur rarely relative to normal air traffic operations. This scarcity produces severe class imbalance that limits predictive models of flight delay. To address it, this dissertation leverages a physics- and domain- knowledge informed Variational Autoencoder (VAE), conditioned on airport identity, that generates physically plausible synthetic weather events for underrepresented TMI categories. The fidelity of the model is assessed with a calibrated discrepancy measure disclosed along- side the results rather than described in free-form terms. A multitask Graph Neural Network (GNN) is then trained on the augmented dataset to jointly classify airport-level TMI status and predict …
Ai-Driven Biomarker Discovery & Progression Modeling For Precision Diagnosis Of Glaucoma, Cheng Huang
Ai-Driven Biomarker Discovery & Progression Modeling For Precision Diagnosis Of Glaucoma, Cheng Huang
Computer Science and Engineering Theses and Dissertations
This dissertation presents a comprehensive study on the integration of artificial intelligence (AI) for glaucoma diagnosis and retinal image analysis. Leveraging multimodal imaging data including fundus photography, Optical Coherence Tomography Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA), the research develops a suite of deep learning frameworks designed to detect early glaucomatous changes with high precision, robustness, and interpretability. A series of novel architectures are introduced, spanning vessel segmentation networks, biomarker discovery pipelines, and multimodal fusion models, all designed to enhance diagnostic accuracy and generalizability across diverse populations. To facilitate reproducible and scalable ophthalmic AI research, this work …
Analysis And Design Of Multi-Winding Current Ballasted Magnetics For Integrated Dc-Dc Conversion, Kishalay Datta
Analysis And Design Of Multi-Winding Current Ballasted Magnetics For Integrated Dc-Dc Conversion, Kishalay Datta
Dartmouth College Ph.D Dissertations
Power conversion circuits have become a bottleneck in terms of reducing the size and cost of modern electronic systems in a vast number of applications ranging from personal devices, to automotive systems, to data centers. This has motivated designs at higher frequencies where smaller passive components can be used. Unfortunately, magnetic components scale poorly to smaller dimensions. In addition, the AC resistance of magnetic components deteriorates due to current crowding effects at high frequencies. This has resulted in fully- integrated power converters with planar magnetic components having efficiencies lower than what may be theoretically achieved. In this work, we investigate …
Degree Assortativity And Estimation Of Degree Distribution In A Contact Network Of People Who Inject Drugs, Peter Geissert
Degree Assortativity And Estimation Of Degree Distribution In A Contact Network Of People Who Inject Drugs, Peter Geissert
Dissertations and Theses
This dissertation analyzes data from a respondent driven sampling (RDS) study of people who inject drugs in Portland, OR. The objective was to assess assumptions for the use of weighted estimators to estimate a population physical contact (syringe sharing) network degree distribution.
Visualization of degree distribution for social and physical networks, Kolmogorov-Smirnov tests of difference, and kernel tests of equivalence were used for comparison of distributions. Spearman's rho and GAM non-parametric regression models were used to test for association and assess non-monotonic relationship. The validity of Markov chain assumptions for RDS was assessed using a transition matrix, Markov chain graphs, …
Polymer Nanocomposite Dielectrics For High-Temperature Superconducting Cables: Cryogenic Characterization And Testing Environment Development, Jared R. Ericksen
Polymer Nanocomposite Dielectrics For High-Temperature Superconducting Cables: Cryogenic Characterization And Testing Environment Development, Jared R. Ericksen
Theses and Dissertations
High-temperature superconducting (HTS) cables require dielectric insulation materials that can withstand cryogenic operating environments while maintaining electrical reliability, mechanical stability, and manufacturing compatibility. This thesis investigates polyamide-based polymer nanocomposites as candidate HTS cable insulation materials and develops cryogenic testing platforms for evaluating thin-film dielectrics at reduced temperatures. Two silicon-based filler systems are studied: sol-gel-derived silicon dioxide (SiO 2 ) nanoparticles and polyhedral oligomeric silsesquioxane (POSS). Dielectric breakdown behavior is evaluated under DC and AC high-potential testing, while mechanical behavior is assessed through tensile testing. The results show that PA/SiO 2 nanocomposites provide the strongest overall balance of mechanical reinforcement and …
From Retrieval To Generation: Building And Evaluating An Ai Accompanist For Piano Duets With An Anticipatory Music Transformer, Sai Ruthvik Uppala
From Retrieval To Generation: Building And Evaluating An Ai Accompanist For Piano Duets With An Anticipatory Music Transformer, Sai Ruthvik Uppala
Masters Theses
Systems that accompany a live musician, such as ACCompanion, work by retrieval: they hold a written accompaniment and stretch its timing to follow the soloist, so they can only accompany music whose second part already exists as a score. This thesis asks whether that second part can instead be generated, and specifically whether a machine learning model can write an accompaniment for a piece whose score it has never seen. A player performs the primo, the melody; a model produces the secondo, the accompaniment; and a score follower places the generated notes against the live performance. If this works, a …
Isolating Human Monocytes And Characterizing Human Macrophage Polarization Through Flow Cytometry And Morphological Analysis, Arthur Peter Klujian
Isolating Human Monocytes And Characterizing Human Macrophage Polarization Through Flow Cytometry And Morphological Analysis, Arthur Peter Klujian
Biomedical Engineering
Peripheral Artery Occlusive Disease (PAOD) is a cardiovascular disease that affects more than 200 million people. It is characterized by atherosclerosis, a biologic process where peripheral arteries are restricted due to a buildup in cholesterol and fats. This eventually leads to ischemia, developing complications such as chronic inflammation and possible limb amputation. The current standard of care for patients includes surgical revascularization and exercise therapy. These treatment strategies have had limited success with alleviating symptoms and restoring perfusion, however, many patients still experience ischemia and do not fully restore blood flow. Further exploration in pursuit of treating these shortcomings led …