Engineering Commons^™

Automated Droplet Manipulation Through Electrowetting On Dielectric For Solid-Phase Oligonucleotide Synthesis, Hee Tae An

Journal of the Microelectronic Engineering Conference

No abstract provided.

Mems Fabrication Of A Peristaltic Pump, Nicholas Amendola

Journal of the Microelectronic Engineering Conference

No abstract provided.

16-11 Microsimulation Of The Impact Of Access Management Practices To Pedestrians, Deo Chimba, Kevin Soloka

Transportation Research Center Reports

The study applied microsimulation to analyze the impact of access management (AM) to the operational performances of vehicles and pedestrians. A conceptual model was developed in VISSIM and VISWALK to examine the effect of access and signals density on different median types to the travel speed, travel time, delay and stopping. Access density, signal density, and presence of median were simulated in a scenario base analysis. The model scenarios shifted through changing both access density and signal density with no median, raised median and TWLT lane to provide interactions of arterial corridors in Nashville. The effect of access density on …

Evaluating The Impact Of Adopting 3d Printing Services On The Retailers, Sharareh Rajaei Dehkordi

Dissertations

As additive manufacturing technology becomes more responsive to consumers’ demand, one important question for the retailers is whether they should provide 3D printing services in their brick-and-mortar store in addition to the traditional off-the-shelf product? If so, what should be the retailers pricing scheme to achieve a higher profit? What should be the optimal inventory level of off-the-shelf products? What is the optimal capacity of 3D printers? In this study, stochastic models are examined to capture the joint optimal 3D product price and capacity of 3D printers to maximize retailer’s expected profit while considering consumer product choices. Moreover, a stochastic …

16-02 Enhancing Non-Motorized Mobility Within Construction Zones, Upul Attanayake, Abul Fazal Mazumder, Wjdan Dhaif Sahi Sahi, Mathew Mueller, Dustin Black

Transportation Research Center Reports

Acquisition of lanes and sidewalks for construction activities increases congestion and delays and compromises safety. Further, work zones impair access to local businesses, bus stops, nearby facilities, etc., while hindering mobility of pedestrians, cyclists, and emergency responders. The emphasis on non-motorized mobility varies significantly when temporary traffic control management plans are developed for small cities. Due to lack of specific instructions given to contractors and the potential liability issues, contractors tend to completely close access to non-motorized traffic without providing alternate routes or detours. Instead of using a detour, pedestrians and cyclists tend to pass through the construction zone or …

Development Of Economic Water Usage Sensor And Cyber-Physical Systems Co-Simulation Platform For Home Energy Saving, Joe Singer

Mechanical Engineering Master's Theses

In this thesis, two Cyber-Physical Systems (CPS) approaches were considered to reduce residential building energy consumption. First, a flow sensor was developed for residential gas and electric storage water heaters. The sensor utilizes unique temperature changes of tank inlet and outlet pipes upon water draw to provide occupant hot water usage. Post processing of measured pipe temperature data was able to detect water draw events. Conservation of energy was applied to heater pipes to determine relative internal water flow rate based on transient temperature measurements. Correlations between calculated flow and actual flow were significant at a 95% confidence level. Using …

Carbon Fiber Electrodes For In Vivo Neural Recording, Esma Cetinkaya

Theses

Multi-channel micro electrodes for neural recording is a growing field that thrives on novel materials and fabrication techniques offered by micro fabrication technology. The material and the design of microelectrodes have a critical role on the quality of neural signals recorded. The neural signals collected by chronic implantation of these devices in experimental animals reveal new information about the brain functions and guide the development of new diagnostic and treatment options for neurological disorders.

Ideally, a microelectrode should meet two important criteria: longevity after implantation and minimal tissue insult. Carbon fibers` high tensile strength and flexibility allow fabrication of micro-scale …

Computational And Experimental Determination Of The Mixing Efficiency Of A Microfluidic Serpentine Micromixer, Siril Arockiam

Theses

In microfluidics, efficiency and mixing time are the greatest disadvantages. These parameters hinder the application of microfluidic devices for biochemical and immunological assays. However, once these disadvantages have been overcome by optimizing the parameters of the microfluidic device, it becomes the important analytical tool. In this experiment, various designs of microfluidic devices have been both simulated using COMSOL software, and experimentally verified to obtain the optimized parameter such as depth and velocity for better mixing efficiency. The COMSOL model has been validated by comparing the results with fluorescent images data of the experiment. The microfluidic device is built with Adhesive …

Electrical Properties Of Metal/Wse2structures, Zeel Rajiv Gandhi

Theses

The formation of low resistance metal contacts on two-Dimensional layer (2-D) of WSe2 is a big challenge. In this research, a comparative study is presented on the electrical properties of metal/WSe2 Schottky barrier diodes with various metals such as Au, In, Al, and Ga in the temperature range of 80K to 400K well within the domain of thermionic emission theory.

Topics covered here include the factors that determine the Schottky barrier height, the device capacitance, and its current-voltage (I-V) characteristics. I-V curves for different metals on WSe2 are analyzed as function of temperature. Barrier height is determined from Au-nWSe2 Schottky …

Comparative Analysis Of The Dissolution Performance Of Aspirin Tablets In The Usp Apparatus 2 And In A Minivessel Dissolution System, Annmarie C. Walker

Theses

Dissolution testing is a critical component of quality control procedures in the pharmaceutical industry in order to ensure that the final solid dosage forms have consistent dissolution properties. Dissolution tests are also routinely conducted to evaluate the in-vitro performance of solid dosage forms during pharmaceutical development, to aid in the behavior of formulations, and to optimize drug release from dosage forms.

The use of compendial dissolution test apparatus and techniques, such as the USP 2 (Paddle), to characterize the dissolution performance of oral drug delivery system is an established area of pharmaceutical science. However, this method is not always appropriate, …

Formulation Of Uv Curable Resins Utilized In Vat Photo Polymerization For The Additive Manufacturing Of Gun Propulsion Charge In 3d Printers, David T. Bird

Theses

Formulating resins for Additive Manufacturing (AM), utilizing UV laser stereolithography, is a new technique that makes it possible for the fabrication of complex geometries with high dimensional resolution. This layer by layer photopolymerization approach spans various industrial sectors from adhesives, inks and optical fibers to nanotechnology and biomaterials. UV curable resins such as epoxides, vinyl ethers and other acrylates are important monomers that offer effective mediums for energetic materials, and the potential exists to develop environmentally friendly formulations with suspended energetic materials at various solids loading levels.

Developing techniques for UV curing formulations of highly loaded energetic suspensions is a …

General Design Procedure For Free And Open-Source Hardware For Scientific Equipment, Shane W. Oberloier, Joshua M. Pearce

Department of Materials Science and Engineering Publications

Distributed digital manufacturing of free and open-source scientific hardware (FOSH) used for scientific experiments has been shown to in general reduce the costs of scientific hardware by 90–99%. In part due to these cost savings, the manufacturing of scientific equipment is beginning to move away from a central paradigm of purchasing proprietary equipment to one in which scientists themselves download open-source designs, fabricate components with digital manufacturing technology, and then assemble the equipment themselves. This trend introduces a need for new formal design procedures that designers can follow when targeting this scientific audience. This study provides five steps in the …

Integrated Assessment Of Shallow-Aquifer Vulnerability To Multiple Contaminants And Drinking-Water Exposure Pathways In Holliston, Massachusetts, Birgit Claus Henn, Yelena Ogneva-Himmelberger, Allegra Denehy, Marcie Randall, Nichole Cordon, Bilin Basu, Brian Caccavale, Stefanie Covino, Ravi Hanumantha, Kevin Longo, Ariel Maiorano, Spring Pillsbury, Gabrielle Rigutto, Kelsey Shields, Marianne Sarkis, Timothy Downs

International Development, Community, and Environment

Half of U.S. drinking water comes from aquifers, and very shallow ones (table) are especially vulnerable to anthropogenic contamination. We present the case of Holliston, a Boston, Massachusetts suburb that draws its drinking water from very shallow aquifers, and where metals and solvents have been reported in groundwater. Community concerns focus on water discolored by naturally occurring manganese (Mn), despite reports stating regulatory aesthetic compliance. Epidemiologic studies suggest Mn is a potentially toxic element (PTE) for children exposed by the drinking-water pathway at levels near the regulatory aesthetic level. We designed an integrated, community-based project: five sites were profiled for …

Monitoring Of Corrosion Process In Structural Adhesive Using Smart Materials, Yee Yan Lim, Iman Izadgoshasb, Scott T. Smith

Dr Iman Izadgoshasb

Luminescence Of Defects In The Structural Transformation Of Layered Tin Dichalcogenides, Peter Sutter, H.P. Komsa, A. V. Krasheninnikov, Y Huang, Eli A. Sutter

Faculty Publications from the Department of Electrical and Computer Engineering

Layered tin sulfide semiconductors are both of fundamental interest and attractive for energy conversion applications. Sn sulfides crystallize in several stable bulk phases with different Sn:S ratios (SnS2, Sn2, S3, and SnS), which can transform into phases with a lower sulfur concentration by introduction of sulfur vacancies (VS). How this complex behavior affects the optoelectronic properties remains largely unknown but is of key importance for understanding light-matter interactions in this family of layered materials. Here, we use the capability to induce VS and drive a transformation between few-layer SnS2 and SnS by electron beam irradiation, combined with in-situ cathodoluminescence spectroscopy …

A Post-American World? Assessing The Cognitive And Attitudinal Impacts Of Challenges To American Exceptionalism, Jason A. Gilmore, Charles Rowling

Languages, Philosophy, and Communication Studies Faculty Publications

A number of voices have emerged in U.S. political discourse questioning the legitimacy of American exceptionalism, suggesting we are in a “post-American world.” Our research examines the effects that political messages that explicitly challenge American exceptionalism can have on U.S. public opinion. Drawing upon social identity theory, we find that explicit challenges to American exceptionalism significantly impact Americans’ views toward their own nation, their willingness to denigrate foreign publics, and their broader foreign policy preferences.

Microfluidic Pore Model Study On Physical And Geomechanical Factors Influencing Fluid Flow Behavior In Porous Media, Shuang Cao

LSU Doctoral Dissertations

Fluid flow in porous media is a subject of fundamental importance and relevant to numerous engineering applications. The comprehensive description of fluid interaction parameters containing wetting properties, fluid-fluid displacement ratio, and capillary pressure, are inevitably needed. Moreover, the fine-grained sediments’ response to various pore fluids and migration in porous media influences reservoir geomechanical properties and pore clogging is essential to a better understanding of fluids flow behavior.

This dissertation provides a detailed study of physical and geomechanical factors influencing fluids flow behavior in porous media. The two-dimensional micromodel tests have been conducted under a wide selection of fluids flow conditions. …

Smart-Based Monitoring Of Epoxy Using Piezoelectric Transducers, Yee Yan Lim, Iman Izadgoshasb, Scott T. Smith

Dr Iman Izadgoshasb

Vortex Detection And Tracking In Massively Separated And Turbulent Flows, Yangzi Huang

Dissertations - ALL

The vortex produced at the leading edge of the wing, known as the leading edge vortex (LEV), plays an important role in enhancing or destroying aerodynamic force, especially lift, upon its formation or shedding during the flapping flight of birds and insects. In this thesis, we integrate multiple new and traditional vortex identification approaches to visualize and track the LEV dynamics during its shedding process. The study is carried out using a 2D simulation of a flat plate undergoing a 45 degree pitch-up maneuver. The Eulerian 𝛤1 function and 𝑄 criterion are used along with the Lagrangian coherent structures (LCS) …

Design Of Tribologically Enhanced Polymeric Materials For Biomedical Applications, Allen Osaheni

Dissertations - ALL

Anytime two surfaces are in normal contact, accompanied by tangential motion, there is potential for deterioration of one or both surfaces. Gradual wear, or the removal of surface material, is typically an undesirable event. Therefore, the need for lubrication arises to minimize the amount of shear stress that develops between opposing surfaces. This reduction in shear stress is characterized by the coefficient of friction (COF). Friction is one of the primary subjects of interest in tribology, the science of the friction and wear of articulating surfaces.

A number of fascinating tribological systems can be found in nature. One example which …

Design, Synthesis And Study Of Thermomechanically Active Polymer Networks Based On Latent Crosslinking Of Semicrystalline Polymers, Wenbin Kuang

Dissertations - ALL

Demand has arisen rapidly for smart materials in the world of the need to develop and understand new functional products like plastics, rubber, adhesives, fibers, and coatings. Such products are essentially composed of polymers, large molecules of high molecular weight with homogeneous or various repeating units, which researchers term “macromolecules” that engender specific structural, morphological, and physical and mechanical properties. Those polymers with the capacity to change their configuration in accordance with environmental alteration are specifically referred to as shape memory polymers (SMPs), attracting much interest of study both academically and industrially. Herein, this dissertation aims at design, fabrication, and …

Accelerated Construction Of Roadways: Life Cycle Assessment And Environmental Impacts, Sudipta Ghorai

Dissertations - ALL

Sustainability refers to a long-term perspective of economic, social, and environmental progress, which not only addresses the present conditions but also includes the needs of future generations. The massive network of roadways in United States has the potential to contribute considerably towards achieving sustainability in the infrastructure sector. The “triple bottom line” of sustainability, if incorporated in roadway development projects, can address issues like climate change, environmental protection, funds optimization, and social equity. This study focuses on the life cycle assessment (LCA) of arterial improvement projects. Preservation treatments help in extending the remaining service life of roads; but at the …

Ensemble Methods For Anomaly Detection, Zhiruo Zhao

Dissertations - ALL

Anomaly detection has many applications in numerous areas such as intrusion detection, fraud detection, and medical diagnosis. Most current techniques are specialized for detecting one type of anomaly, and work well on specific domains and when the data satisfies specific assumptions.

We address this problem, proposing ensemble anomaly detection techniques that perform well in many applications, with four major contributions: using bootstrapping to better detect anomalies on multiple subsamples, sequential application of diverse detection

algorithms, a novel adaptive sampling and learning algorithm in which the anomalies are iteratively examined, and improving the random forest algorithms for detecting anomalies in streaming …

Catalytic Synthesis Of Biodiesel Fuel Under Sub/Supercritical Conditions: Kinetics And Phase Behavior, Jiuxu Liu

Dissertations - ALL

In this thesis, transesterification of triglycerides and esterification of free fatty acids were executed under subcritical and supercritical alcohol conditions, and discussed in Chapter 2-5. The project was initiated by studying the phase behavior and kinetics of transesterification reactions under severe reaction conditions (T: 300-400 oC, P=200 bar), since those conditions were suggested and commonly used in the literature. At these conditions, triglycerides reacted with alcohol within minutes, and the oil-alcohol mixture formed a homogeneous phase which minimized the boundary mass transfer resistance. The composition change of the reaction mixture made the critical point of the system approach supercritical region …

Adsorption Of Iodine And Water On Silver-Exchanged Mordenite, Yue Nan

Dissertations - ALL

The reprocessing of used nuclear fuel to recover the fissile materials generates off gases including radioactive nuclides namely 3H (tritiated water, H3HO), 129I, 85Kr, 135Xe, and 14C. Due to its high quantity in off-gas streams and long half-life (1.59 million years), 129I removal from the off-gas streams is a significant objective of off-gas treatment.

129I retention by solid adsorbents was recognized a better strategy in comparison to liquid scrubbers due to the simplicity of system design and low cost. Among the studied adsorbents, reduced silver-exchanged mordenite (Ag0Z) was widely recognized as the state-of-art adsorbent for iodine removal. It has been …

Development And Evaluation Of A Connective Tissue Phantom Model For Subsurface Visualization Of Cancers Requiring Wide Local Excision, Kimberly S. Samkoe, Brent D. Bates, Niki N. Tselepidakis, Alisha V. Dsouza, Jason R. Gunn, Dipak B. Ramkumar, Keith D. Paulsen, Brian W. Pogue, Eric R. Henderson

Dartmouth Scholarship

Wide local excision (WLE) of tumors with negative margins remains a challenge because surgeons cannot directly visualize the mass. Fluorescence-guided surgery (FGS) may improve surgical accuracy; however, conventional methods with direct surface tumor visualization are not immediately applicable, and properties of tissues surrounding the cancer must be considered. We developed a phantom model for sarcoma resection with the near-infrared fluorophore IRDye 800CW and used it to iteratively define the properties of connective tissues that typically surround sarcoma tumors. We then tested the ability of a blinded surgeon to resect fluorescent tumor-simulating inclusions with ∼1-cm margins using predetermined target fluorescence intensities …

Modifications To Commercial Printers To Enable Multi-Material Fabrication Of 3d Cellular Scaffolds, Lucas D. Albrecht

Theses - ALL

The scarcity of organs for patients that need transplants has led to exceedingly

lengthy waits for organ transplants for sick patients. Fabrication of tissues and organ

constructs in-vitro has potential to end the shortage, however many of the machines

used to create these tissues and organs are expensive, not easy to use, and do not

have any further practical applications. Bioprinting technology has the potential to

revolutionize the fabrication of biological constructs that can be used as in vitro model

tissues and vivo substitutes. Bioprinting is the process of using conventional 3D printing

methods and computer-aided-design (CAD) to create patient …

Cell Laden Hydrogel Microspheres Using 3d Printed Microfluidics, Sanika Nitin Suvarnapathaki

Theses - ALL

Cell laden hydrogel microspheres using 3D printed microfluidics

Abstract

By

Sanika Suvarnapathaki

Current tissue engineering therapies use macro-scale three dimensional (3D) scaffolds to treat tissue defects surgically. Uneven cell seeding and oxygen and media perfusion cause low cell viability in these macro-scale scaffolds. Microencapsulation, a technique of encapsulating cells in biocompatible polymers or hydrogels, has the potential to address these key issues, and therefore this technology has been used for numerous healthcare applications over the last two decades. Cell microencapsulation in hydrogels that mimic the tissue physiology and biochemistry has made it possible to use natural hydrogels like gelatin methacrylate …

Detection, Diagnosis And Mitigation Of Malicious Javascript With Enriched Javascript Executions, Xunchao Hu

Dissertations - ALL

Malicious JavaScript has become an important attack vector for software exploitation attacks and imposes a severe threat to computer security. In particular, three major class of problems, malware detection, exploit diagnosis, and exploits mitigation, bring considerable challenges to security researchers. Although a lot of research efforts have been made to address these threats, they have fundamental limitations and thus cannot solve the problems.

Existing analysis techniques fall into two general categories: static analysis and dynamic analysis. Static analysis tends to produce inaccurate results (both false positive and false negative) and is vulnerable to a wide series of obfuscation techniques. Thus, …

Gas Phase Oxidation Of Levulinic Acid For The Production Of Maleic Anhydride Over Supported Vanadium Oxide Catalysts, Anargyros Chatzidimitriou

Dissertations - ALL

With continued depletion of fossil carbon, there is a need to utilize renewable sources of energy and consumer end products. In this context, we examine the aerobic oxidation of levulinic acid, a bio-based platform chemical derived from lignocellulosic biomass, to produce maleic anhydride, a valuable commodity chemical. This process is carried out over supported vanadium oxide catalysts. Yields as high as 71% of the theoretical maximum were achieved at 573 K over a vanadium oxide catalyst supported on SiO2. The exact mechanism underlying this transformation is complex, but our results suggest that maleic anhydride forms by the oxidative cleavage of …