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Articles 4411 - 4440 of 195925
Full-Text Articles in Engineering
Mental Health And Help-Seeking In Engineering Education: Beliefs, Norms, And Intervention Pathways For Undergraduate Students, Matthew D. Whitwer
Mental Health And Help-Seeking In Engineering Education: Beliefs, Norms, And Intervention Pathways For Undergraduate Students, Matthew D. Whitwer
Theses and Dissertations--Chemical and Materials Engineering
Engineering education is at a critical juncture where supporting student mental health is essential for fostering persistence, equity, and the development of a resilient and innovative workforce. While engineering students experience high levels of distress and low rates of mental health treatment seeking (known as a mental health treatment gap), there is a gap in knowledge around how this compares to that of students in other fields of study. Further, while efforts have been made to improve the mental health treatment gap in engineering, they are limited by a lack of actionable, theory-based targets. Therefore, this dissertation aims to characterize …
A Specification-Driven Framework For Self-Supervised Learning In Specialized Vision Domains, Mahmut S. Gokmen
A Specification-Driven Framework For Self-Supervised Learning In Specialized Vision Domains, Mahmut S. Gokmen
Theses and Dissertations--Computer Science
Self-supervised learning (SSL) has emerged as a principled approach to visual representation learning that derives supervisory signal directly from unlabeled data, enabling foundation models to be trained at scale without manual annotation. Deployments in medical imaging and biometric recognition have demonstrated the potential of this paradigm, yet the assumptions that make SSL effective on natural image benchmarks fail systematically in specialized domains. Generic SSL pipelines encode a tacit assumption that the most informative correspondence is spatial proximity within a single acquisition. In specialized domains this assumption breaks at the level of the data-generating process: the signal that carries domain-specific information …
Linking S‑Pillar Empirical Criteria With Boundary And Finite Element Models For Underground Stone Pillar Analysis, Benjamin Diddle
Linking S‑Pillar Empirical Criteria With Boundary And Finite Element Models For Underground Stone Pillar Analysis, Benjamin Diddle
Theses and Dissertations--Mining Engineering
The objective of this thesis is to strengthen the relationship between empirically based stone pillar design methods and two numerical modeling techniques by calibrating boundary element and finite element models to the S‑Pillar empirical criteria and observed pillar behavior in underground stone mines. The first component of the research investigates the displacement‑discontinuity boundary element method implemented in LaModel, quantifying the influence of the lamination thickness and element size on stone pillar safety factor predictions. Results showed that optimal thickness depends on overburden modulus, while larger element sizes introduce significant SF differences from S-Pillar values once the grid size exceeds 5 …
Validation Of Final And Dynamic Subsidence Prediction Models Using The Influence Function Method, Carlos M. Hernandez Garcia
Validation Of Final And Dynamic Subsidence Prediction Models Using The Influence Function Method, Carlos M. Hernandez Garcia
Theses and Dissertations--Mining Engineering
This study evaluates the Surface Deformation Prediction System (SDPS Version 7) for predicting final and dynamic subsidence in longwall mining. Using the influence function method, SDPS 7 was calibrated using data from the Quarto 7 Mine (Ohio, USA) and two panels in Anhui Province, China, to test the reliability of the method under varying geological and operational conditions, particularly low advance rates.
For the Quarto 7 Mine, monument line C provided the optimal set of subsidence parameters: SSF of 78%, tanβ of 2.97, edge‑effect offset of 160 ft, with an RMSE of 0.108 ft. These values aligned with estimates obtained …
Evaluation Of The Proclivity For Recovering Rare Earth Elements Via Heap Leaching Of Coal And Coal Byproducts, Dylan Connell
Evaluation Of The Proclivity For Recovering Rare Earth Elements Via Heap Leaching Of Coal And Coal Byproducts, Dylan Connell
Theses and Dissertations--Mining Engineering
Rare earth elements (REEs) - 17 elements classified as light (LREE) or heavy (HREE) - underpin modern technology. This thesis presents the development, design, and testing of a heap leach pad (HLP) to extract REEs from Western KY No.13 seam coal refuse. Testing included resource estimation, column and heap leaching, and an economic feasibility study. Drillhole analyses identified average REE concentrations in two refuse piles of 286 ppm and 290 ppm. The resource base totaled approximately 7,085 metric tons of REOs. The HLP, constructed with 2,000 metric tons of coal refuse material, was tested continuously over 308 days. Fresh lixiviant …
Field-Assisted Post-Processing Of Cold-Sprayed Pure Copper, Alan Hensley
Field-Assisted Post-Processing Of Cold-Sprayed Pure Copper, Alan Hensley
Theses and Dissertations--Mechanical and Aerospace Engineering
The properties of materials processed through cold spray, and many other AM processes, are non-uniform and unpredictable. In most cases, post-processing is required to achieve desired properties and better uniformity. In cold spray, the typical method is an annealing heat treatment (AHT), which can improve bond strength, reduce porosity, and restore ductility, among other effects. AHT alone, however, is unable to completely remedy any of the unfavorable properties. In addition, long treatments at high temperatures are often needed for satisfactory results. This increases energy consumption and extends production times for products made by the process. For these reasons, numerous investigations …
Multiphysics Transport In Porous Thermal Protection Systems: Experimental Characterization Of Gas Permeability And Radiative Properties, Yejajul Hakim
Multiphysics Transport In Porous Thermal Protection Systems: Experimental Characterization Of Gas Permeability And Radiative Properties, Yejajul Hakim
Theses and Dissertations--Mechanical and Aerospace Engineering
Porous thermal protection systems (TPS) used in hypersonic vehicles exhibit coupled gas and radiative transport across multiple regimes and length scales. Accurate performance prediction requires reliable characterization of permeability, slip-flow behavior, and radiative transport properties, particularly for low-permeability and charred materials where existing data are limited. This dissertation presents experimental methods for characterizing multiphysics transport in porous TPS materials. A modular flow system was developed to measure permeability and slip behavior in both virgin and charred materials under relevant environments. A transient pressure decay method enables accurate permeability estimation in low-permeability regimes and provides insight into effective pore structure. Results …
Reciprocity-Based Transfer Function Techniques For Acoustic Source Reconstruction, Spring Isolator Characterization And Structural Damping Assessment, David Pum Thian Lal Paite Neihguk
Reciprocity-Based Transfer Function Techniques For Acoustic Source Reconstruction, Spring Isolator Characterization And Structural Damping Assessment, David Pum Thian Lal Paite Neihguk
Theses and Dissertations--Mechanical and Aerospace Engineering
Reciprocity implies that a system responds identically when the source and receiver positions are interchanged. This dissertation applies this principle to address three practical challenges in noise and vibration characterization, where conventional approaches are limited by inaccessible interfaces, constrained excitation conditions, or metrics that do not fully capture vibroacoustic behavior.
The first study develops and validates an inverse method to characterize ducted acoustic sources using acoustic free velocity. Acoustic reciprocity is applied to simplify transfer function measurements. The method is extended to large cross-section ducts, where the source is reconstructed as a collection of point sources along a plane. Validation …
Process-Guided Learning Via Data-Driven Modeling And Controller Synthesis, Benton Clark
Process-Guided Learning Via Data-Driven Modeling And Controller Synthesis, Benton Clark
Theses and Dissertations--Mechanical and Aerospace Engineering
This work introduces process-guided learning, a framework in which process characteristics and learning algorithms are combined in the modeling process of engineering applications with the aim of uniting traditional and data-driven modeling and control techniques. Traditional engineering methods using simplified analytic models fail to capture the increasing complexities of engineering problems with sufficient accuracy to achieve modern requirements. More advanced modeling and control techniques using high-fidelity models often produce a computational burden that is infeasible for real-time solutions. Data-driven modeling offers a simple and flexible algorithm for producing real-time capable, high-fidelity models, but naive implementations lack the physical constraints of …
From Floodplain To Floodplain: Analyzing Stream And Riparian Restoration Methodologies And Impacts, Noah P. Lane
From Floodplain To Floodplain: Analyzing Stream And Riparian Restoration Methodologies And Impacts, Noah P. Lane
Theses and Dissertations--Biosystems and Agricultural Engineering
Stream restoration is a relatively new scientific field. Currently, there is not a definitive methodology for performing restorations that all professionals in industry and academia can agree upon. This has allowed for multiple ideologies to be developed and altered that vary by geographic location and the professional using them. In addition to the methodologies used, the publicly available design guidance published by state government organizations also varies by regulatory authority, method of analysis, ecoregion, and restoration objectives. In some cases, design guidance is replicated from a different geographical area and may not satisfy local needs or existing site conditions. Since …
Constrained Dynamics Of Rapid Orbit Motion Emulator (Rome) Using Udwadia-Kalaba Approach, Keanu Brayman
Constrained Dynamics Of Rapid Orbit Motion Emulator (Rome) Using Udwadia-Kalaba Approach, Keanu Brayman
Honors Undergraduate Theses
The Rapid Orbit Motion Emulator (ROME) is designed to be a hardware-in-the-loop (HIL) testbed for orbital control algorithms. It consists of a four-wheeled ground vehicle and a six-degree-of-freedom robotic manipulator. This work investigates the use of optimal control to execute orbital trajectories on ROME using the Udwadia-Kalaba (UK) formulation to model the system dynamics. The UK formulation is a novel method to derive equations of motion for constrained systems. Unlike traditional approaches, the UK approach can be applied directly to any constrained dynamical system. This project utilizes the UK approach to derive dynamics with trajectory following constraints for the ROME …
Exploring Drone Technology For The Survey And Documentation Of Aerospace Archaeology Sites, David G. Morgan, Thomas R. Allen
Exploring Drone Technology For The Survey And Documentation Of Aerospace Archaeology Sites, David G. Morgan, Thomas R. Allen
Political Science & Geography Faculty Publications
This research examines the implementation of Unmanned Aerial Systems (UAS) during a pilot mission in Nike Park to support its aerospace preservation. Located in Carrollton, Virginia, it was a Cold War missile installation that formed part of the area’s air-defense network. This project aims to use a drone to capture high-resolution video and imagery of Nike Park’s Administrative Office Supply and PX building and the Nike Ajax missile to create virtual 3D models for the Isle of Wight County Museum’s exhibit. For this mission, the DJI Mini 4 Pro drone manually flew a circular flight pattern around the missile and …
Shock The System: Pouring Water On The Cpuc’S Income-Graduated Flat Rates In Favor Of More Effective Rate Structures, Benjamin Hill
Shock The System: Pouring Water On The Cpuc’S Income-Graduated Flat Rates In Favor Of More Effective Rate Structures, Benjamin Hill
Dickinson Law Review (2017-Present)
The volume of rate cases in the United States continues to increase, resulting in constant price hikes for utility customers. The battle between corporate profit and consumer financial satisfaction will likely continue. Considering these diametrically opposed interests, the California Public Utility Commission, at the behest of the California legislature, decreased the rate consumers pay for usage and added fixed fees based on income to utility bills. The broader goals of the Commission’s model are to maintain utility profitability, alleviate the financial burden consumers face, promote energy conservation, and develop energy efficient technology to combat greenhouse gas emissions. This Comment will …
Five Tensions Of Artificial Intelligence Adoption For Organ Allocation: Applying The Technology–Organization–Environment Framework, Amaneh Babaee, Daniel Burton Shank, Casey I. Canfield, Joely Grace Hall, Krista L. Lentine, Henry Randall, Mark Schnitzler
Five Tensions Of Artificial Intelligence Adoption For Organ Allocation: Applying The Technology–Organization–Environment Framework, Amaneh Babaee, Daniel Burton Shank, Casey I. Canfield, Joely Grace Hall, Krista L. Lentine, Henry Randall, Mark Schnitzler
Psychological Science Faculty Research & Creative Works
Background: The US organ transplantation system is pursuing modernization of the allocation process through the integration of new technologies such as artificial intelligence (AI). However, the legal and ethical issues within the transplantation industry are still of concern. Objective: We explore the opportunities and challenges for Organ Procurement Organizations (OPOs) to adopt AI. The US organ transplant system is a highly regulated industry yet open to innovation. Methods: Ten structured interviews were conducted with OPO representatives using the Extended Technology, Organization, Environment (TOE) framework. Results: Overall, we identified five core tensions in AI adoption: (1) misconceptions, (2) approach to training, …
Exploring Aggregate Morphological Characteristics Under Laboratory Polishing For Enhanced Pavement Skid Resistance, Ahmed S. El-Ashwah, Magdy Abdelrahman
Exploring Aggregate Morphological Characteristics Under Laboratory Polishing For Enhanced Pavement Skid Resistance, Ahmed S. El-Ashwah, Magdy Abdelrahman
Civil, Architectural and Environmental Engineering Faculty Research & Creative Works
As the use of recycled asphalt pavement (RAP) in pavement construction grows for sustainable development, it becomes essential to investigate potential frictional deterioration over time. This study evaluated the friction properties of recovered RAP material aggregates compared with raw aggregates across various polishing cycles. The micro-Deval test was employed to simulate aggregate loss of texture, while morphological and friction properties were measured using an aggregate imaging measurement system (AIMS-II), along with a British pendulum tester (BPT) and dynamic friction tester (DFT). Additionally, Fourier transform infrared spectroscopy (FTIR) was employed to assess its potential in determining the origin and composition of …
Evaluation Of Multiple Generative Large Language Models On Neurology Board-Style Questions, Mohammad Almomani, Vijaya Valaparla, James Weatherhead, Xiang Fang, Alok Dabi, Chih Ying Li, Peter Mccaffrey, Dan Hier, Jorge Mario Rodríguez-Fernández
Evaluation Of Multiple Generative Large Language Models On Neurology Board-Style Questions, Mohammad Almomani, Vijaya Valaparla, James Weatherhead, Xiang Fang, Alok Dabi, Chih Ying Li, Peter Mccaffrey, Dan Hier, Jorge Mario Rodríguez-Fernández
Electrical and Computer Engineering Faculty Research & Creative Works
Objective: To compare the performance of eight large language models (LLMs) with neurology residents on board-style multiple-choice questions across seven subspecialties and two cognitive levels. Methods: In a cross-sectional benchmarking study, we evaluated Bard, Claude, Gemini v1, Gemini 2.5, ChatGPT-3.5, ChatGPT-4, ChatGPT-4o, and ChatGPT-5 using 107 text-only items spanning movement disorders, vascular neurology, neuroanatomy, neuroimmunology, epilepsy, neuromuscular disease, and neuro-infectious disease. Items were labeled as lower- or higher-order per Bloom's taxonomy by two neurologists. Models answered each item in a fresh session and reported confidence and Bloom classification. Residents completed the same set under exam-like conditions. Outcomes included overall and …
C.A.S. Full Assessment Report: State Of Florida Government Portal, Delante Clark
C.A.S. Full Assessment Report: State Of Florida Government Portal, Delante Clark
Graduate Scholarship and Creative Works
The purpose of this assessment is to evaluate the cognitive overhead, transparency, and attentional integrity of
official State of Florida digital interfaces using the Cognitive Attentional Standards (C.A.S.) platform.
While the Florida Digital Bill of Rights (FDBR) establishes strict regulatory guardrails for consumer data
transparency, tracking opt-outs, and attentional safeguards, the State of Florida explicitly exempts its own
government agencies, public universities, and non-profit entities from complying with these rules.
This assessment serves to investigate the tension between legislative intent and government execution. By
analyzing public sector websites through the C.A.S. platform, this project will establish a “state-enforced vs.
state-executed” …
River Tay Refreshments Package Design, Blake Studley
River Tay Refreshments Package Design, Blake Studley
Student Research Design & Innovation Symposium
This package design project was created for a junior-level Package Design course. The objective of the project was to develop a custom beverage packaging system inspired by a culturally significant river from another country. The design concept was based on Scotland's River Tay, which is known for one of the largest salmon populations and harvesting industries. The project incorporated elements of Scottish heritage and environmental significance through visual motifs and design. Featured flavors were inspired by major cities located along the River Tay, reinforcing the geographic and cultural connection. Plaid patterns, nature-inspired graphics, and imagery of an otter; an animal …
Solving High-Dimensional Differential Equations Using Recurrent And Residual Neural Network Architectures, Hind Khaled Kolaib
Solving High-Dimensional Differential Equations Using Recurrent And Residual Neural Network Architectures, Hind Khaled Kolaib
Knowledge Engineering and Data Science
High-dimensional Partial Differential Equations (PDEs) form the foundation of complex process modeling in various scientific and engineering applications, including finance, physics, and optimal control. However, classical numerical methods are adversely affected by the curse of dimensionality, making them inapplicable for large-scale problems. Recently, however, deep learning-based approaches have provided a new toolbox for these high-dimensional PDEs, including methods such as the Deep Backward Stochastic Differential Equation (Deep BSDE) method. Our approach draws on a more sophisticated deep learning backbone, using neural networks (in our case, a Residual Neural Network and a Long Short-Term Memory network (LSTM) integrated into the Deep …
Evaluation Of Chromium-Crosslinked Amps-Hpam Copolymer Gels: Effects Of Key Parameters On Gelation Time And Strength, Maryam Sharifi Paroushi, Baojun Bai, Thomas P. Schuman, Yin Zhang, Mingzhen Wei
Evaluation Of Chromium-Crosslinked Amps-Hpam Copolymer Gels: Effects Of Key Parameters On Gelation Time And Strength, Maryam Sharifi Paroushi, Baojun Bai, Thomas P. Schuman, Yin Zhang, Mingzhen Wei
Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works
Controlling CO2 channeling in heterogeneous reservoirs remains a major challenge for both enhanced oil recovery (EOR) and secure geological storage. AMPS-HPAM copolymers exhibit high-temperature resistance and brine tolerance compared with conventional HPAM gels, making them well suited for the harsh environments associated with CO2 injection. Chromium-based crosslinkers (CrAc and CrCl3) were investigated because sulfonic acid groups in AMPS can coordinate with trivalent chromium ions, enabling dual ionic crosslinking and the formation of a robust gel network. While organic crosslinked AMPS-HPAM gels have been widely studied, the behavior of chromium-crosslinked AMPS-containing systems, particularly their gelation kinetics under …
Solubility And Dissolution Mechanism Of Novel Multi-Ester Headgroup Surfactants In Supercritical Co2, Ning Xu, Yan Ling Wang, Baojun Bai, Shi Zhang Cui, Yu Zhang, Wen Jing Shi, Zhao Nian Zhang, Wen Hui Ding, Pei Xu Ma, Zan Gao
Solubility And Dissolution Mechanism Of Novel Multi-Ester Headgroup Surfactants In Supercritical Co2, Ning Xu, Yan Ling Wang, Baojun Bai, Shi Zhang Cui, Yu Zhang, Wen Jing Shi, Zhao Nian Zhang, Wen Hui Ding, Pei Xu Ma, Zan Gao
Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works
To address the limited solubility and applicability of conventional hydrocarbon surfactants in supercritical CO2, a series of multi-ester headgroup surfactants were designed and synthesized by leveraging the CO2-philic properties of ester groups. The molecular structures were characterized using Fourier transform infrared (FT-IR) spectroscopy and 1H NMR. A custom-designed laser-based apparatus was developed to quantify surfactant solubility and systematically investigate phase behavior in CO2. Molecular dynamics (MD) simulations were employed to elucidate structure–solubility relationships across multiple scales, including solubility parameters, interaction energies, radial distribution functions (RDFs), and free volume fractions. Results indicate that, at 323.15 K, …
Unlocking Green Potential In Indonesian Small Medium Enterprises: Challenges And Opportunities For Sustainable Vermicelli Production, Togar W. S. Panjaitan, Karina Agustin, Prayonne Adi, Jani Rahardjo, I Nyoman Sutapa
Unlocking Green Potential In Indonesian Small Medium Enterprises: Challenges And Opportunities For Sustainable Vermicelli Production, Togar W. S. Panjaitan, Karina Agustin, Prayonne Adi, Jani Rahardjo, I Nyoman Sutapa
ASEAN Journal on Science and Technology for Development
Due to limited initiatives and support, the transition to green manufacturing among small and medium enterprises (SMEs) in developing countries remains challenging. Through a critical literature review and case study of the Indonesian vermicelli industry, this study highlights the importance of collaboration and strong policies to address this. Other findings also reveal that the energy intensity and emissions in the sector exceed best practice benchmarks, with the cooking and drying stages contributing significantly to emissions due to high energy consumption. Lack of government regulations, company awareness, and understanding of applicable practices and technologies creates challenges in green manufacturing. The study …
Evaluating The Role Of Power Electronics In Enhancing Renewable Energy And Smart Grid Performance: A Review, Muhammad Irfan Habib
Evaluating The Role Of Power Electronics In Enhancing Renewable Energy And Smart Grid Performance: A Review, Muhammad Irfan Habib
ASEAN Journal on Science and Technology for Development
The review article demonstrates the importance of power electronics in propelling the increase of renewables and increasing the efficiency of contemporary electrical grids. In particular, it highlights the need for bidirectional converters for effective energy management in vehicle-to-grid (V2G) systems with two-way power transfer. The paper examines the series of complications offered by the significantly large integration of power electronic converter-interfaced renewables, such as those related to system steadiness, power quality, and resignation bottlenecks. Also, it recognizes a mix of new technologies, such as wide bandgap (WBG) semiconductors like silicon carbide (SiC) and gallium nitride (GaN), that deliver superior performance …
Artificial Neural Network Based Protection For Dc Bus Using Solid State Dc Breaker, Eswaraiah Giddalur, Askani Jaya Laxmi
Artificial Neural Network Based Protection For Dc Bus Using Solid State Dc Breaker, Eswaraiah Giddalur, Askani Jaya Laxmi
ASEAN Journal on Science and Technology for Development
Low voltage Direct Current (LVDC) microgrids have been extensively used as a hopeful technology with high access to distributed energy resources (DERs) and DC loads, due to the absence of multiple conversions. A high amplitude Fault current together with the vulnerability of electronic devices, poses a great challenge to the line protection in LVDC microgrids. Electromechanical switches are slow and take long tripping time to clear the short circuit fault. Power electronic circuit breakers are used to achieve fast fault interruption recent progress in areas like machine learning and natural language processing have affected nearly every assiduity and area of …
Assessing The Influence Of Land Use Land Cover Alterations On Climate Variability In Thimphu & Chhukha, Sonam Zangpo, Karma Choki, Tashi Tobgay, Phurpa Rinchen, Tandin Tshewang
Assessing The Influence Of Land Use Land Cover Alterations On Climate Variability In Thimphu & Chhukha, Sonam Zangpo, Karma Choki, Tashi Tobgay, Phurpa Rinchen, Tandin Tshewang
ASEAN Journal on Science and Technology for Development
This study examines the spatiotemporal dynamics of land use and land cover (LULC) changes and their influence on local climate variability in Bhutan using an integrated geospatial and machine learning framework. LULC changes during the period 2004 to 2022 were analyzed to understand their relationship with localized climate responses. Despite increasing urbanization pressures, comprehensive assessments linking LULC dynamics with climate variability in Bhutan remain limited. Geographic Information System (GIS) techniques and Random Forest classification were used to map LULC changes, while non-parametric trend analyses (Mann–Kendall test and Sen’s slope estimator) were applied to evaluate trends in key meteorological variables, including …
A Full Polymer Piezoelectric Flextensional Energy Harvester, Nadia Ahbab, Sidra Naz, Bingqi Zhao, Tian-Bing Xu
A Full Polymer Piezoelectric Flextensional Energy Harvester, Nadia Ahbab, Sidra Naz, Bingqi Zhao, Tian-Bing Xu
Mechanical & Aerospace Engineering Faculty Publications
This study presents a full polymer piezoelectric flextensional energy harvester (FPPFEH) comprising a single-layer poly(vinylidene fluoride) (PVDF) film bonded to a 3D-printed polylactic acid (PLA) flextensional frame. For an arm inclination angle of θ=10°, the free-body model gives a theoretical geometric force-amplification factor of MF=cot θ ≈ 5.67; this value represents an ideal upper bound and was not independently validated by local force or strain measurements. During assembly, the film was tensioned only to remove visible slack and maintain a flat configuration. No intentional pretension was applied, and any residual tension was not measured. Off-resonance force-controlled tests showed …
High Temperature Creep Deformation Mechanism Of Fe28.2ni18.8mn32.9al14.1cr6 High Entropy Alloy And Its Modified Alloys, Edwin S. Jiang, I. Baker
High Temperature Creep Deformation Mechanism Of Fe28.2ni18.8mn32.9al14.1cr6 High Entropy Alloy And Its Modified Alloys, Edwin S. Jiang, I. Baker
Dartmouth College Ph.D Dissertations
Fe28.2Ni18.8Mn32.9Al14.1Cr6 eutectic high entropy alloy exhibits a good combination of room-temperature and high temperature properties, including tensile strength, ductility, and corrosion resistance, making it a promising candidate for structural applications in extreme environments. However, the creep deformation behavior of this alloy— and high-entropy alloys (HEAs) in general—remains insufficiently understood. This dissertation systematically investigates the high-temperature creep deformation mechanisms of Fe28.2Ni18.8Mn32.9Al14.1Cr6 and its derivatives.
Creep mechanisms and associated microstructural changes were examined across a wide range of strain rates using strain-rate jump and constant-stress tests. Two dominant regimes were identified: dislocation glide/solute-drag at low strain rates, and dislocation climb at high …
Structural And Magnetic Characterization Of A Magnetite Nanoparticle-Based Aggregation Assay And Its Application To In Vitro Cytokine Monitoring, Gabrielle Rose Moss
Structural And Magnetic Characterization Of A Magnetite Nanoparticle-Based Aggregation Assay And Its Application To In Vitro Cytokine Monitoring, Gabrielle Rose Moss
Dartmouth College Ph.D Dissertations
Magnetic particle spectroscopy (MPS) based aggregation assays rely on target induced changes in functionalized magnetic nanoparticle (fMNP) hydrodynamic diameter and/or changes in fMNP aggregation level to enable target detection. fMNP target binding can be modeled via Brownian and Néel relaxation. We are engineering an MPS-based aggregation assay to sense tumor necrosis factor (TNF)-⍺ in a 3D melanoma tissue culture to aid in the development of immunotherapies for cancer treatment. TNF-⍺ is an inflammatory cytokine, whose production can be linked to cell death.
The first part of this thesis investigates the effects of ligand density, off-target proteins, and salts on fMNP …
Advancing Cns Tumor Management: Novel Modalities In Surgery, Radiation, And Chemotherapy, Armin David Tavakkoli
Advancing Cns Tumor Management: Novel Modalities In Surgery, Radiation, And Chemotherapy, Armin David Tavakkoli
Dartmouth College Ph.D Dissertations
Most tumors affecting the brain and spine are managed through a combination of surgical resection, radiation, and chemotherapy; however, operative morbidity from invasive surgery, the narrow therapeutic window of conventional radiotherapy, and poor blood-brain barrier penetration of systemic agents are critical barriers that hinder long term tumor control. This thesis presents three complementary strategies to advance brain and spine tumor therapy. First, we investigate laser interstitial thermal therapy (LITT) in the treatment of spinal tumors with metastatic epidural spinal cord compression, replacing “separation surgery” with a minimally invasive, image-guided approach that maximizes tumor ablation while preserving neurologic function. Second, we …
Engineering Disorder, Defects, And Electrical Transport For High-Performance Thermoelectric Fe2val Heusler Alloys, James Russell Taylor Iv
Engineering Disorder, Defects, And Electrical Transport For High-Performance Thermoelectric Fe2val Heusler Alloys, James Russell Taylor Iv
Dartmouth College Ph.D Dissertations
Fe2VAl is a promising low-temperature thermoelectric material for waste-heat energy conversion because it is easily processed and comprised of earth-abundant, non-toxic, and low-cost elements. However, viability for applications faces two major challenges: high thermal conductivity and low p-type Seebeck coefficients. This primarily experimental work aims to address these issues through extrinsic and self-doping, point-defect and disorder generation through thermal and electrical processing, disordered and metastable phase composition quantification, and comparison of transport measurements to modeled electronic features.
An accessible phase quantification method was developed for bulk Fe2VAl using laboratory X-ray diffraction equipment to compare thermoelectric properties …