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Articles 25411 - 25440 of 196021
Full-Text Articles in Engineering
Obtaining Sweet Molasses By The Method Of Hydromechanical And Enzymatic Processing Of Grain, Sadritdin Maxamatdinovich Turabdjanov, Kamoliddin Ahmadjonovich Mahmudov, Bexzod Alisherovich Kasimov, Kasun Dissanayake Kumara
Obtaining Sweet Molasses By The Method Of Hydromechanical And Enzymatic Processing Of Grain, Sadritdin Maxamatdinovich Turabdjanov, Kamoliddin Ahmadjonovich Mahmudov, Bexzod Alisherovich Kasimov, Kasun Dissanayake Kumara
Chemical Technology, Control and Management
Methods of hydrolysis of grains to starch under the influence of hydrodynamic and enzymatic processes are logically based. Polysaccharides derived from starchy grains are known and popular in the food industry for their thickening and stabilizing properties. To date, studies that allow for a deeper understanding of the mechanism of interaction of polysaccharide-containing products with their main components, the effect on the set of rheological, organoleptic, physico-chemical properties of food products that determine their functions are relevant.
Mathematical Model Of An Industrial Robot Built On The Basis Of Linear Motion Mechatron Modules, Matyokubov Nurbek Rustamovich, Rakhimov Temurbek Omonboyevich
Mathematical Model Of An Industrial Robot Built On The Basis Of Linear Motion Mechatron Modules, Matyokubov Nurbek Rustamovich, Rakhimov Temurbek Omonboyevich
Chemical Technology, Control and Management
The use of Industry 4.0 technologies in modern production serves to increase production efficiency. Robots and robotic complexes with innovative intelligent control are widely used in industrial production. However, studying their mechanical part, linear motion mechatronic modules and control system is a complex object. The variety and complexity of control methods and operating modes negatively affects the operator's working time and production productivity. In such cases, it is necessary to improve control methods and develop technologies used in industry, including robots and robotic manipulators, which allow to perform short movements with high accuracy and speed. In the article, the mathematical …
Application Of Evolutionary Algorithms For Optimization Of Operation Modes Of Regional Electric Power Systems, Isamiddin Khakimovich Siddikov, Oksana Vitalevna Porubay
Application Of Evolutionary Algorithms For Optimization Of Operation Modes Of Regional Electric Power Systems, Isamiddin Khakimovich Siddikov, Oksana Vitalevna Porubay
Chemical Technology, Control and Management
The paper presents the possibilities of using evolutionary algorithms to solve the problem of optimizing the operation modes of electric power facilities in the presence of constraints in the form of inequalities and equalities. The limits of constraints have a variable character, depending on the generated and consumed energy. Existing methods used for the optimization of modes are based on general principles and approaches to optimization, which usually adapt to the specifics of the problem. In electric power facilities, optimization problems have some peculiarities, among which is the presence of multiple constraints applied to both independent and dependent variables. Many …
Investigating The Rheological Behavior Of A Simple Yield Stress Fluid Under Shear Flows, Francesco Accetta
Investigating The Rheological Behavior Of A Simple Yield Stress Fluid Under Shear Flows, Francesco Accetta
Theses
Many soft materials display unique and complex rheological behavior characterized by a transition from a solid-like to a fluid-like state upon the application of a force that exceeds the threshold to flow, known as the yield stress. Yield stress fluids are found in a wide range of commonly encountered materials including microgels, emulsions, and foams, and have been widely studied by rheologists over the last several decades. Carbopol is a popular polymeric microgel system as it displays simple, non-thixotropic rheological behavior and is typically seen as an ideal yield stress fluid. Previous research has demonstrated the reproducible behavior of shear …
Challenges In Optimization For The Performance On Sustainability Dimensions In Reverse Logistics Social Responsibility, Sumarsono Sudarto, Katsuhiko Takahashi, Mochammad Dewo
Challenges In Optimization For The Performance On Sustainability Dimensions In Reverse Logistics Social Responsibility, Sumarsono Sudarto, Katsuhiko Takahashi, Mochammad Dewo
Makara Journal of Technology
Reverse logistics social responsibility is preferred as the most acceptable solution for addressing the challenges in stakeholders’ debate regarding social responsibility in supply chains because it involves as many actors as possible in the supply chain to perform social responsibility to achieve sustainability. This paper explores the challenges in achieving optimal policies in sustainability dimensions for collection and recycling facilities in reverse logistics. Sustainability dimensions include economic, environmental, and social aspects. The reverse logistics is modeled on System Dynamics, and a simplified statistical analysis using a contour chart is employed in numerical experiments. Results show a narrow area of optimal …
An Animated Introduction To Digital Logic Design, John D. Carpinelli
An Animated Introduction To Digital Logic Design, John D. Carpinelli
Open and Affordable Textbooks
There is a newer edition of this textbook available here.
This book is designed for use in an introductory course on digital logic design, typically offered in computer engineering, electrical engineering, computer science, and other related programs. Such a course is usually offered at the sophomore level. This book makes extensive use of animation to illustrate the flow of data within a digital system and to step through some of the procedures used to design and optimize digital circuits.
All of the animations for this book can be found here: https://digitalcommons.njit.edu/dld-animations/
Validation Of A Biomechanical Injury And Disease Assessment Platform Applying An Inertial-Based Biosensor And Axis Vector Computation, Wangdo Kim, Emir A. Vela, Sean S. Kohles, Victor Huayamave
Validation Of A Biomechanical Injury And Disease Assessment Platform Applying An Inertial-Based Biosensor And Axis Vector Computation, Wangdo Kim, Emir A. Vela, Sean S. Kohles, Victor Huayamave
Publications
Inertial kinetics and kinematics have substantial influences on human biomechanical function. A new algorithm for Inertial Measurement Unit (IMU)-based motion tracking is presented in this work. The primary aims of this paper are to combine recent developments in improved biosensor technology with mainstream motion-tracking hardware to measure the overall performance of human movement based on joint axis-angle representations of limb rotation. This work describes an alternative approach to representing three-dimensional rotations using a normalized vector around which an identified joint angle defines the overall rotation, rather than a traditional Euler angle approach. Furthermore, IMUs allow for the direct measurement of …
Can Artificial Intelligence, Specifically Large Language Models (Llms), Enhance Human Emotional Intelligence Responses In A Small Team Work Environment?, Jason Evans
AI Assignment Library
Compare real-world human responses to potential conflict situations to an artificial intelligence response. Several articles have suggested that LLMs may actually be more successful at modeling proper human emotional responses than factual based responses. The objective of this assignment is for students to discover if and how a LLM can serve as a model for proper responses to minimize conflict and increase team effectiveness. This specific assignment was designed for aviation students, but can be adapted for any small team working environment.
Molecular Dynamics Simulation Of Interfacial Tension Of The Co2-Ch4-Water And H2-Ch4-Water Systems At The Temperature Of 300 K And 323 K And Pressure Up To 70 Mpa, Quoc Truc Doan, Alireza Keshavarz, Caetano R. Miranda, Peter Behrenbruch, Stefan Iglauer
Molecular Dynamics Simulation Of Interfacial Tension Of The Co2-Ch4-Water And H2-Ch4-Water Systems At The Temperature Of 300 K And 323 K And Pressure Up To 70 Mpa, Quoc Truc Doan, Alireza Keshavarz, Caetano R. Miranda, Peter Behrenbruch, Stefan Iglauer
Research outputs 2022 to 2026
Subsurface geologic formations such as depleted hydrocarbon reservoirs, deep saline aquifers and shale formations have been considered promising targets for carbon dioxide and hydrogen storage. A solid understanding of the interfacial properties of multiphase systems, including binary (pure gas-water) and ternary (gas mixtures and water), is vital to assess for reliability and storage capacity of the geological formations. However, most previous experimental and simulation studies for interfacial properties have mainly focused on binary systems at low-medium pressure. Only a few experimental and simulation studies investigated the interfacial tension at high pressure (above 20 MPa) for the CO2-CH4 …
Accomplishments Of Endwall Contouring On Heat Transfer In A Passage Of A Turbine Blade, Kozhikkatil Sunil Arjun, Tide Porathoor Sunny, Narayanan Biju
Accomplishments Of Endwall Contouring On Heat Transfer In A Passage Of A Turbine Blade, Kozhikkatil Sunil Arjun, Tide Porathoor Sunny, Narayanan Biju
Makara Journal of Technology
The study explores axisymmetric endwall contouring with emphasis on the design of novel endwalls capable of heat load reduction. Optimizations with parameterization numerically determined by the endwall of flat shape led to the endwall of the contoured shape with substantial depletion of heat transfer in the passage of the vane. Heat transfer attributes for the generated contoured endwalls were analyzed for the exit Reynolds number of 2 × 106 . Endwall three-dimensional contouring resulted in remarkable changes in secondary flow vortices, jet-to-secondary flow interaction, and film cooling effectiveness on the flat endwall. The results pointed out that the axisymmetric convergent …
Optimization Of A Bioreactor, Ali Alshami
Optimization Of A Bioreactor, Ali Alshami
AI Assignment Library
The primary objective of this assignimentis to learn to work effectively as a team, and to design an experiment where optimization is essential.
Selection Of Materials For A Nuclear Rocket Engine, Marcos Fernandez-Tous
Selection Of Materials For A Nuclear Rocket Engine, Marcos Fernandez-Tous
AI Assignment Library
Selection of materials which will be used in the construct of a nuclear reactor for a space rocket.
Improving Irrigant Flow Characteristics For Enhanced Root Canal Therapy: A Numerical Study, Bibek Banjaday
Improving Irrigant Flow Characteristics For Enhanced Root Canal Therapy: A Numerical Study, Bibek Banjaday
Masters Theses
This numerical study investigates the flow characteristics within a root canal during a manual endodontic treatment. To underscore the difference in root canal geometry, a simplified root canal (frustum of a cone) and a more complex (realistic) root canal geometry were considered. The needle utilized in all simulations is a side-vented 30G KerrHaweIrrigation Probe, KerrHawe SA, Bioggio, Switzerland. For both root canal geometries, the effect of variation of fluid inlet velocity, needle insertion depth, and needle tilt angle on flow characteristics was examined via velocity contours, turbulent intensity, wall shear stress, and streamline and vector plots. The fluid was Sodium …
Investigating The Resistance Properties Of Concrete Containing Waste Carpet Fibers, Faezeh Nejati, Ali Mahboobi
Investigating The Resistance Properties Of Concrete Containing Waste Carpet Fibers, Faezeh Nejati, Ali Mahboobi
Makara Journal of Technology
This research was conducted with the aim of investigating the use of waste carpet fiber (WCF) and assessing the resistance properties of concrete. The main goal of this study was to investigate the effect of the internal processing of concrete containing WCF on increasing its resistance properties. At the same time, the secondary goals pursued in the research included determining the optimal percentages of carpet fibers in improving compressive strength, tensile strength, and bending strength. The materials used included cement, aggregates, water, WCF, and super lubricant. This research applied seven mixing designs: A, B1, B2, C1, C2, D1, and D2. …
Permeability Prediction For Expansive Soil Based On Physical Properties Using Artificial Neural Networks, Ferry Fatnanta, Imam Suprayogi, Nicola Rabb Ranata, Soewignjo Agus Nugroho, Agus Ika Putra
Permeability Prediction For Expansive Soil Based On Physical Properties Using Artificial Neural Networks, Ferry Fatnanta, Imam Suprayogi, Nicola Rabb Ranata, Soewignjo Agus Nugroho, Agus Ika Putra
Makara Journal of Technology
Permeability is a soil parameter related to the construction industry to understand the processes of infiltration, runoff, and settlement. The risk of testing errors is inevitable in permeability investigations, especially in expansive soils. Trial and error in permeability testing becomes difficult due to soils with small pore sizes and large shrinkage expansion. Several studies related to soil physical properties that affect permeability have been conducted. However, the correlation results obtained still have poor accuracy. Artificial neural networks (ANN) are machine learning systems that can change their structure to solve problems that are included in the system. The use of ANNs …
Asymmetric Secondary Flows Above Geometrically Symmetric Surface Roughness, Wen Zhang, Xiang Yang, Xiaowei Zhu, Minping Wan, Shiyi Chen
Asymmetric Secondary Flows Above Geometrically Symmetric Surface Roughness, Wen Zhang, Xiang Yang, Xiaowei Zhu, Minping Wan, Shiyi Chen
Mechanical and Materials Engineering Faculty Publications and Presentations
The mean flow behaviour of a turbulent boundary layer over rough walls is expected to exhibit symmetries that govern the flow dynamics. In particular, when roughness elements are arranged in a spanwise symmetric manner, the mean flow above them should also exhibit spanwise symmetry. This symmetrical consideration has garnered substantial empirical support. We conduct direct numerical simulations (DNS) of flow over aligned cube arrays to test such symmetry considerations further. We vary the surface coverage density from 0.25 % to 6.25 %, and employ an averaging time of about 100 large-eddy turnover times, which is longer than the typical averaging …
The Relaying Network In Free-Space Optical Communications Using Optical Amplifiers In Cascaded Configuration, Ucuk Darusalam, Arockia Bazil Raj, Fitri Yuli Zulkifli, Purnomo Sidi Priambodo, Eko Tjipto Rahardjo
The Relaying Network In Free-Space Optical Communications Using Optical Amplifiers In Cascaded Configuration, Ucuk Darusalam, Arockia Bazil Raj, Fitri Yuli Zulkifli, Purnomo Sidi Priambodo, Eko Tjipto Rahardjo
Makara Journal of Technology
Optical relaying is the best technique to implement free-space optical (FSO) communications as a terrestrial platform. However, atmospheric turbulence (AT) limits the optical-propagation path length. In this study, the implementation of some optical amplifiers (OAs) in cascaded configuration, namely, erbium-doped fiber amplifiers, semiconductor OAs, and Raman amplifiers (RAs), are investigated through simulation. This study aims to search for the maximum link distance of an optical propagation and enhance the FSO performance caused by each configuration of OAs. The optical relaying network consists of three nodes, with each node designed with a space of several kilometers under the influence of AT. …
Reconstructing 42 Years (1979–2020) Of Great Lakes Surface Temperature Through A Deep Learning Approach, Miraj Kayastha, Tao Liu, Daniel Titze, Timothy C. Havens, Chenfu Huang, Pengfei Xue
Reconstructing 42 Years (1979–2020) Of Great Lakes Surface Temperature Through A Deep Learning Approach, Miraj Kayastha, Tao Liu, Daniel Titze, Timothy C. Havens, Chenfu Huang, Pengfei Xue
Michigan Tech Publications
Accurate estimates for the lake surface temperature (LST) of the Great Lakes are critical to understanding the regional climate. Dedicated lake models of various complexity have been used to simulate LST but they suffer from noticeable biases and can be computationally expensive. Additionally, the available historical LST datasets are limited by either short temporal coverage (<30 >years) or lower spatial resolution (0.25° × 0.25°). Therefore, in this study, we employed a deep learning model based on Long Short-Term Memory (LSTM) neural networks to produce a daily LST dataset for the Great Lakes that spans an unparalleled 42 years (1979–2020) at …30>
Bim And Digital Twins In Infrastructure Projects: An Overview From The Transportation Professional's Perspective, Natállia Mendes
Bim And Digital Twins In Infrastructure Projects: An Overview From The Transportation Professional's Perspective, Natállia Mendes
LSU Master's Theses
Transport infrastructure has undergone significant changes in recent years due to the digitalization of construction methods. Consequently, there is an increasing demand for more productive and cost-effective technologies to optimize various aspects such as time, cost, changes, waste, and errors in projects. Notably, technologies such as Building Information Modeling (BIM) and Digital Twin (DT) hold the potential to enhance the performance of infrastructure projects. While BIM has received substantial attention in recent years, Digital Twin is relatively new to the construction industry. This leads to a scarcity of studies on DT and its integration with other emerging technologies like BIM. …
2023 Fall Engr 333 Project Assignment: Calvin Carbon Neutrality Date Project, Matthew K. Heun
2023 Fall Engr 333 Project Assignment: Calvin Carbon Neutrality Date Project, Matthew K. Heun
ENGR 333
Description
The Fall 2023 ENGR333 project focused on the carbon neutrality date for Calvin University. In 2017, then-president Michael LeRoy committed Calvin to carbon neutrality by 2057, which seems rather too far into the future from the perspective of 2023. I asked the students “What earlier year should Calvin University choose for its carbon neutrality date?”
Customer
The customer for this project was Dr. Wiebe Boer, President of Calvin University.
Evaluating Frozen Soil Properties With Electrical Resistivity Measurement And Electro-Magnetic Induction Methods, Rui Liu
Theses and Dissertations
Electromagnetic induction was utilized in the past by the United States Army Corps of Engineers as a method of detecting unexploded ordinance, while it has the potential to act as a novel method of investigating frozen soils in cold regions. In this study, we performed lab-scale 1D electrical resistivity measurements under freeze-thaw circumstances on frost-susceptible soils with varied soil properties. We implemented an empirical model from our experiments into a COMSOL finite element model at both laboratory and field scales to simulate soil electrical resistivity response under both short-term and long-term sub-freezing conditions. Dynamic temperature-dependent soil properties, most notably unfrozen …
Calculating The Difference In Stiffness Of Living T Cells Through Micropipette Aspiration, Minju Lee
Calculating The Difference In Stiffness Of Living T Cells Through Micropipette Aspiration, Minju Lee
McKelvey School of Engineering Graduate Student Theses & Dissertations
Cardiovascular disease (CVD) accounted for 17.9 million deaths in 2019, with fibrosis contributing to nearly a quarter of these fatalities [1,2]. Fibrosis, characterized by excessive connective tissue formation, has been strongly linked to T cells, essential components of the immune system. This study explores the mechanisms of T cell activation and the subsequent changes in biophysical properties like diameter, stiffness, and elasticity, aiming to develop therapeutic strategies for fibrosis-related diseases, including CVD. Utilizing the micropipette aspiration technique, we accurately assessed T cell stiffness and observed a change in bulk cell stiffness upon activation. The results demonstrated increased fluid-like behavior in …
Design And Implementation Of An Instrument Package For Measuring Process Conditions In An Expeller, Md Masud Rana
Design And Implementation Of An Instrument Package For Measuring Process Conditions In An Expeller, Md Masud Rana
LSU Master's Theses
The expeller process variable has gained increasing attention in research to validate process flow models. The expeller process is a mechanical method used to extract oil and water from seeds, nuts and polymers. Various factors, such as the speed of the press, size, and shape of the expeller, temperature, pressure, and moisture content, impact the efficiency and quality of the oil and water extraction process. By understanding these variables, researchers can develop accurate process flow models to predict the efficiency and quality of the oil and water extraction process. In this research, A custom instrumentation package have designed and implemented …
Thermoresponsive Polymers With Lcst Transition: Synthesis, Characterization, And Their Impact On Biomedical Frontiers, Yichun Yuan, Konpal Raheja, Nathalie B. Milbrandt, Sophia Beilharz, Steffy Tene, Solomon Oshabaheebwa, Umut A. Gurkan, Anna Cristina S. Samia, Metin Karayilan
Thermoresponsive Polymers With Lcst Transition: Synthesis, Characterization, And Their Impact On Biomedical Frontiers, Yichun Yuan, Konpal Raheja, Nathalie B. Milbrandt, Sophia Beilharz, Steffy Tene, Solomon Oshabaheebwa, Umut A. Gurkan, Anna Cristina S. Samia, Metin Karayilan
Faculty Scholarship
Advances in thermoresponsive materials have significantly impacted many biomedical fields. The unique behavior of reversible phase transition close to the physiological temperatures makes these types of materials a great candidate for a wide variety of biomedical applications including bioimaging, biosensing, injectables, smart surfaces, adhesives, biomanufacturing, and tissue engineering. Thermoresponsive behavior, mainly lower critical solution temperature (LCST) can be easily tuned by shifting the balance between hydrophobicity and hydrophilicity (e.g., by using comonomers or changing end groups) and modifying the molecular weight and architecture of the polymer. Hence, synthetic and characterization tools are critical in tailoring and precisely determining these properties. …
Real-Time Length Sensing Of Braided Pneumatic Actuator Using Ir Time-Of-Flight Sensor, Luon B. Chung
Real-Time Length Sensing Of Braided Pneumatic Actuator Using Ir Time-Of-Flight Sensor, Luon B. Chung
Dissertations and Theses
Braided Pneumatic Actuators (BPAs) are used widely in robotics as artificial muscles because of their similar characteristics to biological muscles. When a BPA is pressurized, it expands in the radial direction and contracts in the longitudinal direction. The contraction generates a pulling force that is dependent on the input pressure and BPA length. Biological muscle also behaves in the same way where a pulling force is generated on a contraction. To control BPAs on a robot, the real-time pressure and length measurements are necessary. In this dissertation, I present a new method to measure length of BPAs in real-time using …
Reaction Pathways, Kinetic Modelling And Parameter Estimation Of Heterogeneous Catalytic Trans-Esterificationprocess, Owolabi,R. U, Aderinsola A. P
Reaction Pathways, Kinetic Modelling And Parameter Estimation Of Heterogeneous Catalytic Trans-Esterificationprocess, Owolabi,R. U, Aderinsola A. P
Mansoura Engineering Journal
The kinetics of heterogeneous catalyzed trans-esterification between castor oil and methanol was studied and modeled. Kinetic data was obtained from a perfectly mixed slurry batch reactor. The modeling was conducted via the modified-hattori mechanism to determine the exact rate controlling step for the reaction. A total of five rate expressions were formed, which were as a result of; methanol adsorption, Triglyceride adsorption, Formation of the complex, Surface reaction and Glycerol desorption. Evaluation of best fitting model and parameter estimation was done using the nealder simplex least square optimization algorithm with the aid MATLAB software. The result from the regression analysis …
Improving Square Skirted Foundations Behavior On Sand, Tamer Al-Shyoukhi, Ayman Altahrany, Mahmoud Elmeligy
Improving Square Skirted Foundations Behavior On Sand, Tamer Al-Shyoukhi, Ayman Altahrany, Mahmoud Elmeligy
Mansoura Engineering Journal
Shallow foundations' behavior is enhanced by using skirts to confine the soil beneath the foundation. The bearing capacity and settlement of skirted foundations resting on the sand are influenced by the size of the skirt cell and shear strength of sand. Experimental modelling was carried out on an axially square-skirted footing resting on sand in this study. Plaxis-3D software was used for numerical analysis to support the experimental results. The numerical analysis results validated the experimental results. The outcomes of the study demonstrated that skirts wider than the footing size increased the bearing capacity of skirted foundations. In the case …
Large-Scale Cascading Of First-Order Fbg Array In A Highly Multimode Coreless Fiber Using Femtosecond Laser For Distributed Thermal Sensing, Farhan Mumtaz, Bohong Zhang, Ronald J. O'Malley, Jie Huang
Large-Scale Cascading Of First-Order Fbg Array In A Highly Multimode Coreless Fiber Using Femtosecond Laser For Distributed Thermal Sensing, Farhan Mumtaz, Bohong Zhang, Ronald J. O'Malley, Jie Huang
Electrical and Computer Engineering Faculty Research & Creative Works
This research focuses on the performance analysis and characterization of a fiber Bragg gratings (FBGs) array, consisting of 10 first order FBGs inscribed by a femtosecond (FS) laser in a highly multimode coreless fiber. The study evaluates the FBG array's ability to function as a distributed thermal sensing (DTS) platform, with the coreless fiber chosen as the sensing element due to its immunity to dopant migration at high temperatures. The design of a large cascaded first-order FBG array effectively eliminates unwanted harmonic peaks across a wide spectrum range. In contrast, higher-order FBGs introduce limitations due to the overlapping of Bragg …
A Framework And Approach For Leveraging Unsteady Response In Turbocompressor Flowfields, Eric M. Krivitzky
A Framework And Approach For Leveraging Unsteady Response In Turbocompressor Flowfields, Eric M. Krivitzky
Dartmouth College Ph.D Dissertations
Turbomachinery is an essential technology in the transfer of mechanical work to or from a fluid stream. Forming a cornerstone component in nearly all electrical energy production and air transportation propulsion systems, turbomachinery also accounts for significant en- ergy transfer due to its omnipresence in fluid handling, including water pumping and pro- cess machinery. As system designers look towards optimized arrangements that enhance system flexibility to highly variable conditions, increase the density of energy transfer, and reduce the amount of lost work, the performance and operability demands on turbomachin- ery components continue to increase. For turbocompressors, a turbomachinery subtype that …
Bacterial Extraction And Concentration From Blood Through Filtration Processes, Ryan L. Wood, Rebecca Prymak, Evelyn Welling, Alayna Bedwell, Jordan T. Wood, Damian E. Teasley, Magdalena Crofts, Hope Callister Anderson, Clifton M. Anderson, W Cameron Beard, Jacob Stepan, Alexandra Carter, William G. Pitt
Bacterial Extraction And Concentration From Blood Through Filtration Processes, Ryan L. Wood, Rebecca Prymak, Evelyn Welling, Alayna Bedwell, Jordan T. Wood, Damian E. Teasley, Magdalena Crofts, Hope Callister Anderson, Clifton M. Anderson, W Cameron Beard, Jacob Stepan, Alexandra Carter, William G. Pitt
Faculty Publications
Blood stream infections (BSIs) are challenging to rapidly and precisely diagnose. Current clinical diagnostic methods for BSI identification require culturing the blood sample for many hours prior to identifying the bacteria and possible antibiotic resistance. Removing the culturing step from the bacterial identification process of a BSI provides a significant reduction in the processing time, but shifts the rate-limiting step from the growth time to the concentration procedure, since CFU levels in clinical blood samples can be as low as 10 CFU/mL in blood. This study developed a novel whole blood filtration method to concentrate bacteria from a BSI without …