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Articles 18511 - 18540 of 196383
Full-Text Articles in Engineering
Context Dependent Training Data Selection For Automatic Target Detection., Tylman Michael
Context Dependent Training Data Selection For Automatic Target Detection., Tylman Michael
Electronic Theses and Dissertations
An Automatic Target Detection (ATD) algorithm is capable of identifying the location of targets of interest captured by Infra-Red imagery in vastly different contexts. ATD is often a precursor in a 2-stage methodology in order to ascertain the location and nature of a target in both military and civilian applications. In order to train an ATD algorithm, a large amount of data from varied sources is required. One drawback of this requirement is that some sources of data may harm the performance of the method in different contexts. This thesis explores utilizing an unsupervised method to identify a subset of …
Rockin’ Rehab: Novel Rocking Chair For Children With Spinal Cord Injury To Enable Trunk Muscle Activation And Detect Muscle Activation Patterns., Johnathan Jay George
Rockin’ Rehab: Novel Rocking Chair For Children With Spinal Cord Injury To Enable Trunk Muscle Activation And Detect Muscle Activation Patterns., Johnathan Jay George
Electronic Theses and Dissertations
Introduction: Activity-based locomotor training improves trunk control in children with spinal cord injury (SCI), and there is need for additional activities to allow these children to activate trunk muscles. The purpose of this research was to design, fabricate, and evaluate a rocking chair for children with SCI, and to investigate the activation of muscles during use. Sensorization of the chair to confirm muscle activation is also explored. Methods: Quality Function Deployment (QFD) design methodologies identified and ranked needs and features for the rocking chair. A design was developed and evaluated via finite element analysis. The chair was fabricated and tested …
Multithreaded Applications On The Heterogeneous Research Computing Environment., Sungbo Jung
Multithreaded Applications On The Heterogeneous Research Computing Environment., Sungbo Jung
Electronic Theses and Dissertations
Bioinformatics is a domain that has experienced rapid research growth in recent years, as evidenced by the increasing number of articles in biomedical databases such as PubMed, which adds over a million publications every year. However, this also poses a challenge for researchers who need to find relevant citations for their work. Therefore, developing efficient indexing and searching methods for text data is crucial for Bioinformatics. One key technique for information retrieval is document inversion, which involves creating an inverted index to enable efficient searching through vast collections of text or documents. This Ph.D. research aims to design the research …
A Computational Framework For Predicting Cell-Specific Nucleo-Cytoskeletal Forces, Madison Leigh Goldfeldt
A Computational Framework For Predicting Cell-Specific Nucleo-Cytoskeletal Forces, Madison Leigh Goldfeldt
Boise State University Theses and Dissertations
Understanding the influence of mechanical forces on cell function and fate is crucial in unraveling the intricate mechanisms that govern cellular behavior. The cytoskeleton, a dynamic network of protein filaments, plays a pivotal role in sensing and transmitting mechanical cues within cells. The nucleus relies on cytoskeletal mechanical input through nuclear envelope adaptor proteins to sense external stimuli and respond by regulating intra-nuclear chromatin organization. This research provides a means for examining the interplay between mechanical forces and the cytoskeleton in regulating various cellular processes, including cell adhesion, migration, division, and differentiation. Through studying and simulating the cellular response to …
Porcine Computational Modeling To Investigate Developmental Dysplasia Of The Hip, Chia-Yu Yu
Porcine Computational Modeling To Investigate Developmental Dysplasia Of The Hip, Chia-Yu Yu
Boise State University Theses and Dissertations
While it is well-established that early detection and initiation of treatment of developmental dysplasia of the hip is crucial to successful clinical outcome, research on mechanics of the hip joint during healthy and pathological hip development in infants has been limited. Quantification of mechanical behavior in both the healthy and dysplastic developing joints may provide insight into the causes of developmental dysplasia of the hip and facilitate innovation in treatment options. In this study, subject-specific three-dimensional finite element models of two pigs were developed: one healthy pig and one pig with induced dysplasia in the right hindlimb. The objectives of …
Exploring The Effects Of Dopants On The Opto-Electrical Response Of Ge2Se3-Based Optically Gated Transistor (Ogt), Md Faisal Kabir
Exploring The Effects Of Dopants On The Opto-Electrical Response Of Ge2Se3-Based Optically Gated Transistor (Ogt), Md Faisal Kabir
Boise State University Theses and Dissertations
In this work, the electrical and optical responses of chalcogenide glass (ChG) Ge2Se3-based optically gated transistors (OGTs) were investigated. The device can act as a selector for resistive memory devices and potentially enable the production of functional high-density resistive (and memristive) arrays.
The OGT was developed using a Ge2Se3-based material heterostructure and demonstrated to successfully gate a memristor with light. The light intensity provided a built-in compliance current, allowing multi-state programming. By varying the light intensity incident on Ge2Se3 material, a family of current-voltage (I-V) curves were measured that …
Evaluating The Synergy Of Geocell And Microbial-Induced Calcite Precipitation (Micp) In Enhancing Pavement Base Stability: A Field Study On Us 95, Mabin Dahal
Boise State University Theses and Dissertations
The imperative to develop resilient and sustainable infrastructure is escalating, particularly as urban road networks are subjected to unprecedented stresses. Conventional pavement bases often entail the extensive utilization of quarry materials, which significantly exacerbates environmental degradation and amplifies the energy footprint of construction endeavors. The extraction, transportation, and processing of these quarry materials contribute to deforestation, habitat eradication, and greenhouse gas emissions. Given these environmental and operational hurdles, the quest for innovative, sustainable alternatives in pavement engineering is pressing. One solution is to use the native materials treated with microbial-induced calcite precipitation (MICP) alongside geocell technology back in pavement construction …
Effect Of Swirl Ratio On Simulated Vortech Chamber Vortex Parameters, Samuel Kolar
Effect Of Swirl Ratio On Simulated Vortech Chamber Vortex Parameters, Samuel Kolar
Civil Engineering Undergraduate Honors Theses
A numerical simulator can use computational fluid dynamics (CFD) to model an experimental tornado-simulating chamber at Texas Tech University (known as VorTECH). Previous studies evaluating this particular CFD model have produced results that compare the touchdown swirl ratio (STD), core radius (rc), maximum tangential velocity at touchdown (Vtmax @ STD), and height of the maximum tangential velocity (zc) reasonably well with experimental data from the VorTECH facility. The effects of swirl ratio beyond STD on important vortex parameters including rc, Vtmax, z …
The Effect Of Weather On Atc Complexity And Traffic Volume In Washington Air Route Traffic Control Center (Zdc) High Sectors, Amber Mccraw
The Effect Of Weather On Atc Complexity And Traffic Volume In Washington Air Route Traffic Control Center (Zdc) High Sectors, Amber Mccraw
Theses and Dissertations
The purpose of this study was to investigate the effect of weather on ATC complexity and traffic volume in ZDC high sectors in clear vs. convective weather using the AS&T Complexity Tool. This relationship was examined from a combined sector and individual sector perspective using both raw data and daily means for ATC complexity and traffic volume. This study employed an ex post facto effects-type design that used flight trajectory data from the FAA’s System-Wide Information Management (SWIM) Flight Data Publication Service (SFDPS) and weather data from NOAA spanning the year of 2019.
The primary analysis involved raw ATC complexity …
Microwave Imaging Technique For Breast Cancer Detection, Nure Alam Chowdhury
Microwave Imaging Technique For Breast Cancer Detection, Nure Alam Chowdhury
Theses and Dissertations
Breast cancer is a global problem, and it is inevitable to detect cancerous cells at early stages. In recent years, microwave imaging technology has been widely applied in biomedical applications for its non-ionizing radiation. In this study, we design a micro-strip patch antenna with an inverted T-type notch in the partial ground to detect tumor cells inside the human breast. The size of the current antenna is small enough (18 mm × 21 mm × 1.6 mm) to distribute around the breast phantom. The operating frequency has been observed from 6–14 GHz with a minimum return loss of −61.18 dB …
High-Fidelity 3d Reconstruction Of Space Bodies Using Machine Learning And Neural Radiance Fields, Timothy Jacob Huber
High-Fidelity 3d Reconstruction Of Space Bodies Using Machine Learning And Neural Radiance Fields, Timothy Jacob Huber
Theses and Dissertations
In the era of burgeoning space exploration, the growing population of spacecraft heightens the inevitability of collisions. While traditional imagery remains effective for damage assessment, its lack of 3D representation of the object necessitates more advanced approaches. This research delves into cutting-edge methodologies, with a primary focus on leveraging machine learning and computer vision technologies to enhance the precision and efficiency of damage assessment by taking imagery of a space body and creating a 3D model. The study extensively investigates TransMVSNet, a neural network code employing classical computer vision techniques such as multi-vision stereo (MVS) and depth maps. This approach …
Investigating Endothelial Damage During Ischemic Stroke Treatment Using In Vitro And Computational Models, Zackary Lorton
Investigating Endothelial Damage During Ischemic Stroke Treatment Using In Vitro And Computational Models, Zackary Lorton
Theses and Dissertations
Large vessel occlusion during acute ischemic strokes requires mechanical thrombectomy (MT) procedures using stent retrievers (SR). However, complete clot removal typically takes several attempts, which can amplify endothelial cell injury (EI). This project aims to characterize the extent of EI during MT using an in vitro vascular platform and a finite-element model (FEM). Impact of SR diameter and characterization of SR mechanical forces are assessed and correlated with human umbilical vein endothelial cell (HUVEC) response. HUVECs were seeded on fibronectin (4 µg/cm2) coated true-scale PDMS arterial phantoms with 2.5 mm luminal diameter. Test groups (n=6) either …
Synthesis Of Durable Zeolite 13x Insertion Coatings And Scaled-Up Experimental Demonstration For Co2 Capture, Daniel Jamil Hocheimy
Synthesis Of Durable Zeolite 13x Insertion Coatings And Scaled-Up Experimental Demonstration For Co2 Capture, Daniel Jamil Hocheimy
Theses and Dissertations
Minimizing the energy requirement for capturing carbon dioxide (CO2) from post-combustion sources is critical to efficient industrial decarbonization and subsequent mitigation of the effects of climate change. The current portfolio of CO2 capture technologies includes absorption, membrane separation and packed bed adsorption, which suffer from high energy and temperature requirements, scalability, and location dependency issues. Adsorption-based systems could cater to these concerns; however, their current embodiments primarily use packed adsorbent bed design and electricity-driven vacuum pumps to regenerate them. While simple and easy to fabricate, these designs are not scalable and cannot use heat to regenerate them …
Simulating And Training Autonomous Rover Navigation In Unity Engine Using Local Sensor Data, Christopher Pace
Simulating And Training Autonomous Rover Navigation In Unity Engine Using Local Sensor Data, Christopher Pace
Senior Honors Theses
Autonomous navigation is essential to remotely operating mobile vehicles on Mars, as communication takes up to 20 minutes to travel between the Earth and Mars. Several autonomous navigation methods have been implemented in Mars rovers and other mobile robots, such as odometry or simultaneous localization and mapping (SLAM) until the past few years when deep reinforcement learning (DRL) emerged as a viable alternative. In this thesis, a simulation model for end-to-end DRL Mars rover autonomous navigation training was created using Unity Engine, using local inputs such as GNSS, LiDAR, and gyro. This model was then trained in navigation in a …
Test And Evaluation Model For Midwater Docking Of Autonomous Underwater Vehicles, Parker Baillon
Test And Evaluation Model For Midwater Docking Of Autonomous Underwater Vehicles, Parker Baillon
Theses and Dissertations
This research created a Test and Evaluation (T&E) model for midwater Autonomous Underwater Vehicle (AUV) capture. The creation of this model will allow for a better assessment of the feasibility of midwater AUV capture. To achieve this, the T&E model was exposed to various flow conditions to assess stability. Capturing an AUV in midwater, the area below the wave-affected zone to the sea floor, has many benefits for an AUV and its mission. AUVs basing missions from a midwater dock will not be affected by wave motions. A midwater dock can be transported to any mission site and deployed with …
Representation Learning For Generative Models With Applications To Healthcare, Astronautics, And Aviation, Van Minh Nguyen
Representation Learning For Generative Models With Applications To Healthcare, Astronautics, And Aviation, Van Minh Nguyen
Theses and Dissertations
This dissertation explores applications of representation learning and generative models to challenges in healthcare, astronautics, and aviation.
The first part investigates the use of Generative Adversarial Networks (GANs) to synthesize realistic electronic health record (EHR) data. An initial attempt at training a GAN on the MIMIC-IV dataset encountered stability and convergence issues, motivating a deeper study of 1-Lipschitz regularization techniques for Auxiliary Classifier GANs (AC-GANs). An extensive ablation study on the CIFAR-10 dataset found that Spectral Normalization is key for AC-GAN stability and performance, while Weight Clipping fails to converge without Spectral Normalization. Analysis of the training dynamics provided further …
4-Channel Spatially Multiplexed Communication System In Single-Core Optical Fibers, Ce Su
4-Channel Spatially Multiplexed Communication System In Single-Core Optical Fibers, Ce Su
Theses and Dissertations
This dissertation delves into exploring and advancing spatial domain / space division multiplexing (SDM) technologies within single-core optical fibers, a frontier in optical fiber communications poised to meet the burgeoning global demand for data transmission. At the heart of this research is the pursuit to significantly enhance the capacity and efficiency of optical fiber communication systems without necessitating additional fiber infrastructure. This work unveils a new paradigm in optical fiber communications characterized by a pioneering 4-channel SDM system through a meticulous process encompassing theoretical modeling, computational simulations, design innovations, and rigorous experimental validations. Theoretical contributions include the development of refined …
Spin Disorder Control Of Topological Spin Texture, Hongrui Zhang, Yu-Tsun Shao, Xiang Chen, Binhua Zhang, Tianye Wang, Fanhao Meng, Kun Xu, Peter Meisenheimer, Xianzhe Chen, Xiaoxi Huang, Piush Behera, Sajid Husain, Tiancong Zhu, Hao Pan, Yanli Jia, Nick Settineri, Nathan Giles-Donovan, Zehao He, Andreas Scholl, Alpha N'Diaye, Padraic Shafer, Archana Raja, Changsong Xu, Lane W. Martin, Michael F. Crommie, Jie Yao, Ziqiang Qiu, Arun Majumdar, Laurent Bellaiche, David A. Muller, Robert J. Birgeneau, Ramamoorthy Ramesh
Spin Disorder Control Of Topological Spin Texture, Hongrui Zhang, Yu-Tsun Shao, Xiang Chen, Binhua Zhang, Tianye Wang, Fanhao Meng, Kun Xu, Peter Meisenheimer, Xianzhe Chen, Xiaoxi Huang, Piush Behera, Sajid Husain, Tiancong Zhu, Hao Pan, Yanli Jia, Nick Settineri, Nathan Giles-Donovan, Zehao He, Andreas Scholl, Alpha N'Diaye, Padraic Shafer, Archana Raja, Changsong Xu, Lane W. Martin, Michael F. Crommie, Jie Yao, Ziqiang Qiu, Arun Majumdar, Laurent Bellaiche, David A. Muller, Robert J. Birgeneau, Ramamoorthy Ramesh
Physics Faculty Publications and Presentations
Stabilization of topological spin textures in layered magnets has the potential to drive the development of advanced low-dimensional spintronics devices. However, achieving reliable and flexible manipulation of the topological spin textures beyond skyrmion in a two-dimensional magnet system remains challenging. Here, we demonstrate the introduction of magnetic iron atoms between the van der Waals gap of a layered magnet, Fe3GaTe2, to modify local anisotropic magnetic interactions. Consequently, we present direct observations of the order-disorder skyrmion lattices transition. In addition, non-trivial topological solitons, such as skyrmioniums and skyrmion bags, are realized at room temperature. Our work highlights …
The National Center For Reliable Electric Power Transmission Test Facility, Anna Corbitt, Wesley G. Schwartz, Chris Farnell, Juan Carlos Balda, H. Alan Mantooth
The National Center For Reliable Electric Power Transmission Test Facility, Anna Corbitt, Wesley G. Schwartz, Chris Farnell, Juan Carlos Balda, H. Alan Mantooth
Electrical Engineering and Computer Science Faculty Publications and Presentations
Globally, new technological solutions are being studied and developed by researchers in the field of power and energy systems. Before these solutions can be integrated into society as marketable products, thorough testing and validation of the design must be conducted. The National Center for Reliable Electric Power Transmission (NCREPT) is a unique high-power test facility located at the University of Arkansas, Fayetteville, AR, USA. NCREPT is a 12,000-square-foot laboratory space capable of testing power levels up to 6 MVA and offers testing at both the 480 V and 13.8 kV levels. NCREPT's capabilities expand outside of the scope of simply …
Geometric Multi-Resolution Analysis Across Signals, Images, And Networks, Felicia Schenkelberg
Geometric Multi-Resolution Analysis Across Signals, Images, And Networks, Felicia Schenkelberg
Dartmouth College Master’s Theses
This research delves into the transformative potential of Geometric Multi-Resolution Analysis (GMRA) as a robust tool for dimensionality reduction and data analysis in the context of high-dimensional graphs. Statistical techniques for classification have historically been tailored for scenarios wherein the number of observations significantly exceeds the number of features, a paradigm characteristic of low-dimensional datasets. However, recent advancements in technologies have ushered in a transformative era in data collection practices across diverse domains, resulting in the acquisition of extensive feature measurements. As a result of this shift, datasets have transitioned into a high-dimensional realm wherein the number of features significantly …
Fin Design Topology Optimization For Direct Liquid Cooling Of Multichip Power Modules, Aniket Ajay Ladd, Eric Roman, Yue Zhao, William P. King, Nenad Miljkovic
Fin Design Topology Optimization For Direct Liquid Cooling Of Multichip Power Modules, Aniket Ajay Ladd, Eric Roman, Yue Zhao, William P. King, Nenad Miljkovic
Electrical Engineering and Computer Science Faculty Publications and Presentations
This article demonstrates the use of topology optimization (TO) to generate optimal fin designs capable of high heat flux removal without increasing the pumping power. We use pseudo-3-D modeling validated against 3-D simulations for thermal-hydraulic performance, which reduces the computational intensity and allows for a wider range of designs to be considered. The accuracy of the pseudo-3-D modeling is aided by allowing the heat transfer coefficient to vary locally with the flow conditions, in contrast to other studies that often assume constant heat transfer coefficient independent of surface shape. We generated TO designs with density fields representing six different conventional …
Modeling Vibration Stiffness: An Analytical Extension Of Hertzian Theory For Angular Contact Bearings With A Thin Viscoelastic Coating, Davis R. Burton
Modeling Vibration Stiffness: An Analytical Extension Of Hertzian Theory For Angular Contact Bearings With A Thin Viscoelastic Coating, Davis R. Burton
Honors Theses
This thesis considers the novel angular contact rolling-element bearings proposed by NASA’s Glenn Research Center, which are coated with a thin solid lubricant that exhibits viscoelastic behavior. Current analytical models for the dynamic stiffness matrix of angular contact bearings, critical for vibration analysis, lack the ability to model the effects of a solid coating, as well as the time dependencies inherent in viscoelastic theory. The author first presents an overview of the stiffness matrix derivation, followed by a treatment of the underlying Hertzian contact theory. An analytical extension of this theory is proposed which accounts for a thin elastic layer …
The Epitaxial Growth Of Ge And Gesn Semiconductor Thin Films On C-Plane Sapphire, Emmanuel Wangila, Calbi Gunder, Petro M. Lytvyn, Mohammad Zamani-Alavijeh, Fernando Maia De Oliveira, Serhii Kryvyi, Hryhorii Stanchu, Aida Sheibani, Yuriy I. Mazur, Shui-Qing Yu, Gregory J. Salamo
The Epitaxial Growth Of Ge And Gesn Semiconductor Thin Films On C-Plane Sapphire, Emmanuel Wangila, Calbi Gunder, Petro M. Lytvyn, Mohammad Zamani-Alavijeh, Fernando Maia De Oliveira, Serhii Kryvyi, Hryhorii Stanchu, Aida Sheibani, Yuriy I. Mazur, Shui-Qing Yu, Gregory J. Salamo
Physics Faculty Publications and Presentations
Ge1−xSnx growth on a new sapphire platform has been demonstrated. This involved the growth of GeSn on Ge/GaAs layers using the algorithm developed. The resultant growths of Ge on GaAs/AlAs/sapphire and Ge1−xSnx on Ge/GaAs/AlAs/sapphire were investigated by in situ and ex situ characterization techniques to ascertain the surface morphology, crystal structure, and quality. The growth mode of Ge on GaAs was predominantly two-dimensional (2D), which signifies a layer-by-layer deposition, contributing to enhanced crystal quality in the Ge/GaAs system. The growth of Ge1−xSnx with 10% Sn on a graded profile for 30 …
Algorithm-Based Linearly Graded Compositions Of Gesn On Gaas (001) Via Molecular Beam Epitaxy, Calbi Gunder, Mohammad Zamani-Alavijeh, Emmanuel Wangila, Fernando Maia De Oliveira, Aida Sheibani, Serhii Kryvyi, Paul C. Attwood, Yuriy I. Mazur, Shui-Qing Yu, Gregory J. Salamo
Algorithm-Based Linearly Graded Compositions Of Gesn On Gaas (001) Via Molecular Beam Epitaxy, Calbi Gunder, Mohammad Zamani-Alavijeh, Emmanuel Wangila, Fernando Maia De Oliveira, Aida Sheibani, Serhii Kryvyi, Paul C. Attwood, Yuriy I. Mazur, Shui-Qing Yu, Gregory J. Salamo
Physics Faculty Publications and Presentations
The growth of high-composition GeSn films in the future will likely be guided by algorithms. In this study, we show how a logarithmic-based algorithm can be used to obtain high-quality GeSn compositions up to 16% on GaAs (001) substrates via molecular beam epitaxy. Herein, we use composition targeting and logarithmic Sn cell temperature control to achieve linearly graded pseudomorph Ge1−xSnx compositions up to 10% before partial relaxation of the structure and a continued gradient up to 16% GeSn. In this report, we use X-ray diffraction, simulation, secondary ion mass spectrometry, and atomic force microscopy to analyze and …
Revealing The Three-Dimensional Arrangement Of Polar Topology In Nanoparticles, Chaewa Jeong, Juhyeok Lee, Hyesung Jo, Jaewhan Oh, Hionsuck Baik, Kyoung-June Go, Junwoo Son, Si-Young Choi, Sergey Prosandeev, Laurent Bellaiche, Yongsoo Yang
Revealing The Three-Dimensional Arrangement Of Polar Topology In Nanoparticles, Chaewa Jeong, Juhyeok Lee, Hyesung Jo, Jaewhan Oh, Hionsuck Baik, Kyoung-June Go, Junwoo Son, Si-Young Choi, Sergey Prosandeev, Laurent Bellaiche, Yongsoo Yang
Physics Faculty Publications and Presentations
In the early 2000s, low dimensional ferroelectric systems were predicted to have topologically nontrivial polar structures, such as vortices or skyrmions, depending on mechanical or electrical boundary conditions. A few variants of these structures have been experimentally observed in thin film model systems, where they are engineered by balancing electrostatic charge and elastic distortion energies. However, the measurement and classification of topological textures for general ferroelectric nanostructures have remained elusive, as it requires mapping the local polarization at the atomic scale in three dimensions. Here we unveil topological polar structures in ferroelectric BaTiO3 nanoparticles via atomic electron tomography, which …
Biophysical Model Of Retraction Motor Neurons And Their Modification By Operant Conditioning, Maria Rasheed
Biophysical Model Of Retraction Motor Neurons And Their Modification By Operant Conditioning, Maria Rasheed
Dissertations and Theses (Open Access)
Operant conditioning (OC) is a form of associative learning in which an animal modifies its behavior based on the consequences that follow that behavior. Despite its ubiquity, the underlying mechanisms of OC are poorly understood. Insights into the mechanisms of OC can be obtained by studying Aplysia feeding behavior as it can be modified by OC. This behavior is mediated by a central pattern generator (CPG) network in the buccal ganglia that contains a relatively small number of neurons. This CPG generates rhythmic motor patterns (BMPs) that move food into the gut by closing a tongue-like structure (i.e., radula) during …
Testing Resilience Of Microalgae Biofilms When Exposed To Hydrothermal Liquefaction Aqueous Phase, Davis Riley Haag
Testing Resilience Of Microalgae Biofilms When Exposed To Hydrothermal Liquefaction Aqueous Phase, Davis Riley Haag
Undergraduate Honors Capstone Projects
There are a multitude of experimental and processing techniques in the bioenergy field that produce sustainable and carbon negative to carbon neutral methods of converting renewable resources into biologically based hydrocarbons. One example of a process is hydrothermal liquefaction (HTL) which specializes in converting wet biomass into biocrude oil. One reason that these processes are not used outside experimental testing is due to the high cost of performing these processes. There is potential to move these processes to larger scale testing and eventually industrial adaptation if breakthroughs are made to offset the process expenses. There is a waste product produced …
A Reinforcement Learning Framework For Powertrain Control Including Shared Learning Among A Fleet Of Vehicles, Lindsey Kerbel
A Reinforcement Learning Framework For Powertrain Control Including Shared Learning Among A Fleet Of Vehicles, Lindsey Kerbel
All Dissertations
The transportation sector provides a significant opportunity to reduce global emissions, both through technological advancements and vehicular control strategies. Model-based control systems are popular methods for increasing the operating efficiency of vehicles. However, these systems often rely on models that require costly calibrations that still fail to capture the complexity of modern powertrain systems and the variations found in real-world driving. The recent availability of operational data through connected vehicle technology and/or edge devices has led to the emergence of data-driven control strategies that can learn optimal control policies through the interactions of the vehicle’s control system with the environment. …
An In Vitro Investigation Of Urothelial Cell Function In Response To Hypoxia And Pressure In Relation To Bladder Outlet Obstruction, Britney Hudson
An In Vitro Investigation Of Urothelial Cell Function In Response To Hypoxia And Pressure In Relation To Bladder Outlet Obstruction, Britney Hudson
All Dissertations
Bladder outlet obstruction (BOO) is a prevalent urological condition and can be characterized by the presence of lower urinary tract symptoms (LUTS), such as hesitancy, weak stream, and nocturia. The main cause of BOO is a partial blockage of the urethra, which results in elevated voiding pressure, high storage pressure, and tissue ischemia, which are thought to be the triggers of bladder inflammation and subsequent fibrosis. Often patients do not seek treatment until the conditions get severe. Thus, it would be ideal to have an early diagnostic tool to detect changes in the bladder due to BOO. Extracellular vesicles (EVs) …
Locally Injectable Peptide Hydrogel For Conversion Of Temozolomide And Codelivery Of Sirna In Glioblastoma Multiforme Treatment, Megan Pitz
All Dissertations
Traditional treatment methods for glioblastoma multiforme (GBM) are largely unsuccessful, with a 5-year survival rate of 5.6%. Temozolomide (TMZ), the only chemotherapy FDA-approved for GBM treatment, is a hydrophobic prodrug that is stable in an acidic pH and begins converting to its active form at a physiological pH of 7.4. However, complete conversion of TMZ is observed only at a higher pH, and only about 30% of administered TMZ reaches the central nervous system. Therefore, there is a need for new treatment methods that maximize TMZ delivery to and efficacy at the tumor site. Self-assembling peptides are a unique class …