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Articles 14011 - 14040 of 198026
Full-Text Articles in Engineering
Affordable And Sustainable: Innovating Filament Extrusion For Recycled Materials, Turab S. Rizvi
Affordable And Sustainable: Innovating Filament Extrusion For Recycled Materials, Turab S. Rizvi
UROP Posters
The chemical stability, toxicity and non-biodegradability of the polymers pose a significant environmental threat. Addressing end-of-life treatment sustainability is crucial for mitigating these issues. The customized Lyman filament extruder in the Advanced Magnetic Materials Processing Laboratory represents an innovative approach to advancing sustainability in renewable energy production and CO₂ mitigation. Redesigning the thermal system and screw operation will tackle key challenges, including precise temperature control, consistent material flow to handle diverse recycled materials. Integrating an advanced thermal regulation system will reduce the energy consumption by maintaining optimal thermal conditions, thereby lowering the CO₂ footprint of the recycling process. The optimized …
Systematic Co-Culture Of Ipsc-Cm And Ipsc-An Promote Co-Maturation In Vitro, William Gregory Terrell Jr.
Systematic Co-Culture Of Ipsc-Cm And Ipsc-An Promote Co-Maturation In Vitro, William Gregory Terrell Jr.
Graduate Dissertations and Theses
The cardiac microenvironment is a complex system of multicellular interactions that enables proper heart function. In native heart muscle, sympathetic neurons (SN) and parasympathetic neurons (PSN) modulate the beat rate of cardiomyocytes (CM) to maintain homeostasis. Pluripotent stem cells can differentiate into CM, but differentiated CMs are fetal-like, with a high beat rate, and lack organized sarcomeric structure. Recent reports of co-cultured pluripotent CM/SN pairs have reported electrophysiological changes in the SN (increased upstroke velocity). However, interpretation of these results are obscured by the differences in co-culture parameters between studies (stage of development, co-culture duration, etc.). The goal of this …
Precast Foundation For Steel Lattice Towers, Wessam Ramadan
Precast Foundation For Steel Lattice Towers, Wessam Ramadan
All ETDs from UAB
Steel lattice towers are essential structures used in power transmission, telecommunications, and wind turbine towers, where they must withstand various loads to ensure stability and durability. The foundation system plays a crucial role in supporting these towers, with different types chosen based on soil conditions, environmental factors, and project requirements. Traditional foundations, such as drilled shafts, spread footings, and steel grillages have been widely used but often come with challenges, including long installation times, high labor costs, and difficult site conditions. As demand for transmission infrastructure grows, there is a need for faster, more efficient, and environmentally friendly foundation solutions. …
3d Printing Metal Horn Antennas Using Periodic And Aperiodic Perforated Designs For Directed Energy Applications, Alexis Valencia
3d Printing Metal Horn Antennas Using Periodic And Aperiodic Perforated Designs For Directed Energy Applications, Alexis Valencia
Open Access Theses & Dissertations
In the past decade, Additive Manufacturing (AM) has proven to be groundbreaking yet reliable technology. Not only has it revolutionized the way we approach problems in research, design, and production but it has enabled burgeoning discoveries and methods due to the technologyâ??s efficiency, speed, and low manufacturing cost. One area that benefits greatly from this includes radio frequency (RF) devices like horn antennas. At the moment, most horn antennas produced by conventional manufacturing are expensive, heavy, and limited in customization, yet they are necessary for various systems like satellite communication, radar, radio astronomy, and more. 3D printing technology would alleviate …
Navigating Big Data In Cyber Archaeology: An Updated Four-Field Approach Applied To San Miceli, Jared Wilson
Navigating Big Data In Cyber Archaeology: An Updated Four-Field Approach Applied To San Miceli, Jared Wilson
Dissertations
Problem
This dissertation examines the evolving role of digital technologies in archaeological research, focusing on the management and interpretation of extensive digital datasets generated by modern excavations. Drawing on six years of comprehensive fieldwork at San Miceli, Sicily, this study critically evaluates and updates the established four-field methodology proposed by Levy et al. (2012), encompassing acquisition, analysis, dissemination, and curation. While traditional archaeological documentation methods rely heavily on analog techniques, these approaches increasingly fall short due to the rapid expansion and complexity of digital data.
Method
To address this gap, the dissertation refines and expands the current methodological framework by …
Quantum-Resilient Architectures For Enterprise And Cloud Information Systems, Implications Of Quantum Computing For Enterprise Cybersecurity And Data Integrity, Manikantha Varaprasad Inakollu
Quantum-Resilient Architectures For Enterprise And Cloud Information Systems, Implications Of Quantum Computing For Enterprise Cybersecurity And Data Integrity, Manikantha Varaprasad Inakollu
Computer Science and Engineering Faculty Publications
The emergence of quantum computing presents unprecedented challenges to contemporary enterprise cybersecurity frameworks. Current cryptographic systems that protect sensitive data and secure communications will become vulnerable to quantum attacks within the next decade. This research examines the implications of quantum computing advancement for enterprise and cloud information systems, proposing quantum-resilient architectural frameworks that can withstand both classical and quantum threats. We analyze the timeline of quantum computing development, assess vulnerabilities in existing enterprise security infrastructures, and evaluate post-quantum cryptographic approaches suitable for organizational implementation. Through comparative analysis of quantum-resistant algorithms and architectural patterns, this study demonstrates that enterprises must begin …
Blockchain-Enabled Trust Frameworks For Enterprise Information Systems, Establishing Verifiable Trust In Distributed Organizational Environments, Manikantha Varaprasad Inakollu
Blockchain-Enabled Trust Frameworks For Enterprise Information Systems, Establishing Verifiable Trust In Distributed Organizational Environments, Manikantha Varaprasad Inakollu
Computer Science and Engineering Faculty Publications
Enterprise information systems increasingly operate in distributed environments where traditional trust mechanisms based on centralized authority prove insufficient. This research develops a comprehensive blockchain-enabled trust framework that establishes verifiable, decentralized trust mechanisms for enterprise systems operating across organizational boundaries. The study addresses critical gaps in current enterprise architectures where trust depends on centralized intermediaries, creating single points of failure and limiting inter-organizational collaboration. Through examination of existing trust models and blockchain capabilities, we propose an integrated framework that combines cryptographic verification, distributed consensus, and smart contract automation to establish trust without centralized control. Our framework enables organizations to verify data …
Flame Boundary Effects Of Hydrogen-Air Premixing, Alecson L. De Lima Junior
Flame Boundary Effects Of Hydrogen-Air Premixing, Alecson L. De Lima Junior
Honors Undergraduate Theses
The objective of this research was to investigate the reaction of hydrogen and heated air premixing when injected into a combusting ethylene-air crossflow, and to study the flame stabilization location with varying premixing levels. The main parameter of this investigation was the flame stabilization diagnosed through chemiluminescence, based on recorded equivalence ratio, temperature, and flame boundaries, and maintaining a constant air temperature, hydrogen and air mass flow, and momentum flux ratios. Testing was conducted at different ratios of hydrogen and air premixing achieved through alternating the distance between the point where hydrogen and air are mixed and the combusting crossflow. …
Integrated Qfd-Triz Optimization Method For Satellite Solar Array Design In Cost-Sensitive Environment, Hongyi Zhang, Liang Su
Integrated Qfd-Triz Optimization Method For Satellite Solar Array Design In Cost-Sensitive Environment, Hongyi Zhang, Liang Su
International Journal of Aviation, Aeronautics, and Aerospace
With the rapid evolution of commercial space markets in the new space era, satellite design philosophy is transitioning from "performance supremacy" toward "cost-effectiveness priority." This research concentrates on solar arrays, a critical component representing 15%-20% of satellite costs, addressing limitations in traditional design methodologies that inadequately coordinate user requirements and lack systematic frameworks for cost-performance collaborative optimization. We propose a solar array optimization methodology predicated on the integration of Quality Function Deployment (QFD) and the Theory of Inventive Problem Solving (TRIZ). This methodology incorporates cost dimensions through an extended QFD matrix, employs TRIZ to resolve technical contradictions, and develops a …
Suas Agricultural Aerial Application Operational Field Test, David Thirtyacre, Joseph Cerreta, Scott S. Burgess
Suas Agricultural Aerial Application Operational Field Test, David Thirtyacre, Joseph Cerreta, Scott S. Burgess
International Journal of Aviation, Aeronautics, and Aerospace
One of the most promising uses of aerial applications by a sUAS is on small farms where traditional crewed aerial applicators were not practical due to the limited size of the operations. This controlled field test aimed to assess the feasibility and cost-effectiveness of using a sUAS spreading system compared to the traditional manual application of weed killer and fertilizer on cranberry bogs in Western Washington that were less than 10 acres. The aerial application took place over two separate days as scheduled by the farmer for maximum product efficiency. A total of sixty-three flights were necessary to apply the …
Bibliometric Analysis With R Biblioshiny On Safety Behavior In Aviation, Büşra Yıldırım, İnan Eryılmaz, Ahmet Karacan, Nusret Erceylan
Bibliometric Analysis With R Biblioshiny On Safety Behavior In Aviation, Büşra Yıldırım, İnan Eryılmaz, Ahmet Karacan, Nusret Erceylan
International Journal of Aviation, Aeronautics, and Aerospace
Safety behaviors in aviation are not limited to technical knowledge and skills in ensuring the safety of flight operations, but also include the attitudes, decision-making processes and collaborations of individuals and teams. In this context, in this study, a bibliometric analysis of publication and citation trends, key concepts and interactions of studies in the field was conducted to identify current and potential trends in aviation and safety behavior-based research, and to explore the intersections between safety behavior and aviation studies and the areas waiting to be explored. The bibliometric analysis using the RStudio-based Biblioshiny program was conducted on 1065 articles …
Mitigating Information Overload In Aviation Safety: Ai-Driven Hierarchical Tagging And Summarization Of Notam For Pre-Flight Information Bulletin, Rutong Gu, Yefeng Qu, Dongling Chen, Yu Tang, Ailin Zhou
Mitigating Information Overload In Aviation Safety: Ai-Driven Hierarchical Tagging And Summarization Of Notam For Pre-Flight Information Bulletin, Rutong Gu, Yefeng Qu, Dongling Chen, Yu Tang, Ailin Zhou
International Journal of Aviation, Aeronautics, and Aerospace
To address the challenges of aviation safety information overload in Pre-flight Information Bulletin (PIB) systems, this study proposes an intelligent classification framework (ERNIE-DPCNN) that integrates knowledge-enhanced semantic representation with a Deep Pyramid Convolutional Network. Traditional systems relying on rule-based filtering mechanisms suffer from inefficiencies in critical information identification and high risks of human misjudgment. The proposed framework achieves breakthroughs through three technical innovations: (1) An aviation domain-adapted ERNIE model is constructed, leveraging phrase-level masking strategies to enhance semantic representation of compound identifiers; (2) A Deep Pyramid Convolutional Network (DPCNN) is designed to extract multi-granularity features via hierarchical convolution-pooling architecture, optimized …
Innovative Bird Strike Mitigation Strategies: Integrating Drones And Cutting-Edge Technologies To Enhance Airport Safety, Abdellah Hanine, Abdellah Elbarkany
Innovative Bird Strike Mitigation Strategies: Integrating Drones And Cutting-Edge Technologies To Enhance Airport Safety, Abdellah Hanine, Abdellah Elbarkany
International Journal of Aviation, Aeronautics, and Aerospace
Notwithstanding significant efforts to reduce the risk of bird strikes at and around airports, as well as advancements in technology, aviation safety continues to be threatened by this hazard. Our study of recent data shows a clear historical increase in accidents, therefore underscoring the flaws in present technologies. Although among the technologies in common use are radar, drones, cameras, and acoustic approaches, they are not always able to completely meet the challenging needs of bird strike risk mitigation. This approach creatively blends these four fundamental technologies by means of enhanced real-time data processing and targeted drone deployment. While providing more …
Design, Implementation, And Testing Of Spatial Disorientation Scenarios In A Modified Hexapod Motion Simulator, Jarod Hinckley, Ryan Paul, Logan Rock, Joe Conner, Jon M. Loffi
Design, Implementation, And Testing Of Spatial Disorientation Scenarios In A Modified Hexapod Motion Simulator, Jarod Hinckley, Ryan Paul, Logan Rock, Joe Conner, Jon M. Loffi
International Journal of Aviation, Aeronautics, and Aerospace
Abstract
Investigations into aviation accidents aim to identify root causes and enhance safety. Despite advancements in safety measures, technology, and education, general aviation accident rates remain stable, with loss of control identified as the leading cause. Spatial disorientation is a significant contributing factor in these incidents, accounting for approximately 10% of general aviation accidents—90% of which are fatal. Addressing spatial disorientation is increasingly critical with the emergence of Advanced Air Mobility (AAM) vehicles, a sector projected to reach a $30 billion market by 2030. While AAM is expected to transition toward full autonomy, human pilots will operate these vehicles during …
Generalizing Classification Of Pilot Workload: Transfer Learning Versus A Jepa-Inspired Transformer Architecture, Naim Barnett, Shivani Nagrecha, Morgan Glover, Clayton Harper, Justin Wilson, James Maher, Eric C. Larson
Generalizing Classification Of Pilot Workload: Transfer Learning Versus A Jepa-Inspired Transformer Architecture, Naim Barnett, Shivani Nagrecha, Morgan Glover, Clayton Harper, Justin Wilson, James Maher, Eric C. Larson
International Journal of Aviation, Aeronautics, and Aerospace
Within the context of learning, there poses difficulty when objectively measuring human performance. In this work, we investigate the evaluation of human performance via its relation to the individual's mental capacity by classification of cognitive load within the domain of aviation. By utilizing a mixed virtual and physical flight simulation environment in conjunction with biometric sensing, we create and evaluate the predictive capabilities of a Joint-Embedding Predictive Architecture (JEPA) and compare the architecture and results to traditional methods for transfer learning and domain adaptation. We find that our JEPA inspired architecture can achieve more than 70% accuracy of cognitive workload, …
Advances In Ocean Mapping And Nautical Cartography, Giuseppe Masetti, Ian Church, Anand Hiroji, Ove Andersen
Advances In Ocean Mapping And Nautical Cartography, Giuseppe Masetti, Ian Church, Anand Hiroji, Ove Andersen
Center for Coastal and Ocean Mapping
The Special Issue of Geomatics on "Advances in Ocean Mapping and Nautical Cartography" addresses emerging methodologies, technologies, and applications in ocean mapping. This collection includes studies on the development of high-resolution seabed mapping techniques, innovative data processing for marine cartography, and advancements in hydrographic surveying. It highlights the importance of integrating geospatial data from sources such as remote sensing, autonomous underwater vehicles, and satellite-based observations. Additionally, articles discuss challenges and strategies for ensuring data accuracy and accessibility, reflecting a growing interest in sustainable marine resource management and navigation safety enhancements.
Your Foot Is Not A Brick: Using A Multi-Segment Foot Model To Explore The Actions Of The Ankle-Foot Complex During Uneven Terrain Gait., Tayler Jon Hoekstra
Your Foot Is Not A Brick: Using A Multi-Segment Foot Model To Explore The Actions Of The Ankle-Foot Complex During Uneven Terrain Gait., Tayler Jon Hoekstra
Dissertations and Theses
The field of biomechanics has seen continued development of models to be used and circumstances to be considered. An increasing number of more complex models for the foot known as multi-segment foot models (MSFMs) have created opportunities to better understand the compensatory motion of this vital portion of human anatomy. This research seeks to utilize one such MSFM model to increase understanding in how human ambulation changes in uneven terrain environments. Unique inner-foot joints defined by the Rizzoli foot model (RFM) were measured for and compared for subjects traversing both even and uneven terrain to quantify joints that experienced significant …
Afit Generative Ai Teaching Guidebook, Afit Faculty Learning Community, Mark G. Bateman, Brett J. Borghetti, Allen W. Dukes, Nicholas C. Francis, Mike Frick, Bobbie Oh, Kevin Patterson, Hiren J. Patel, Mark G. Reith, Erick S. Tyndall, Teresa M. Walton, Torrey J. Wagner, Timothy S. Wolfe, Jonathan Zemmer
Afit Generative Ai Teaching Guidebook, Afit Faculty Learning Community, Mark G. Bateman, Brett J. Borghetti, Allen W. Dukes, Nicholas C. Francis, Mike Frick, Bobbie Oh, Kevin Patterson, Hiren J. Patel, Mark G. Reith, Erick S. Tyndall, Teresa M. Walton, Torrey J. Wagner, Timothy S. Wolfe, Jonathan Zemmer
AFIT Documents
AFIT is proud to highlight the Generative AI Teaching Guidebook, a resource designed to provide military educators with practical insights, strategies, and use cases for integrating Generative AI (Gen AI) into their teaching practices. Developed through a collaborative effort involving AFIT faculty across various departments within the Graduate School of Engineering and Management and the School of Systems and Logistics, this digital resource serves as a starting point for educators exploring how to leverage Gen AI in their classrooms. It offers accessible examples and best practices, ensuring utility for instructors of all technical backgrounds. The guidebook provides a comprehensive overview …
Afit Generative Ai Teaching Guidebook Synopsis, Afit Faculty Learning Community, Mark G. Bateman, Brett J. Borghetti, Allen W. Dukes, Nicholas C. Francis, Mike Frick, Bobbie Oh, Kevin Patterson, Hiren J. Patel, Mark G. Reith, Erick S. Tyndall, Teresa M. Walton, Torrey J. Wagner, Timothy S. Wolfe, Jonathan Zemmer
Afit Generative Ai Teaching Guidebook Synopsis, Afit Faculty Learning Community, Mark G. Bateman, Brett J. Borghetti, Allen W. Dukes, Nicholas C. Francis, Mike Frick, Bobbie Oh, Kevin Patterson, Hiren J. Patel, Mark G. Reith, Erick S. Tyndall, Teresa M. Walton, Torrey J. Wagner, Timothy S. Wolfe, Jonathan Zemmer
AFIT Documents
The main objective of this work was to bring together various perspectives on how to envision incorporating Gen AI capabilities into the learning environment and identify some best practices for their implementation. Any instructor who is interested in these capabilities but does not necessarily have a technical background can find pragmatic use of the examples provided. While the examples have a wide range of applicability, they are meant to serve as a starting point for educators to explore what would be beneficial to their educational environment, from traditional classroom settings to online continuing education courses.
A Comprehensive Exploration Of 6g Wireless Communication Technologies, Md Nurul Absar Siddiky, Muhammad Enayetur Rahman, Md. Shahriar Uzzal, H. M. Dipu Kabir
A Comprehensive Exploration Of 6g Wireless Communication Technologies, Md Nurul Absar Siddiky, Muhammad Enayetur Rahman, Md. Shahriar Uzzal, H. M. Dipu Kabir
Electrical & Computer Engineering Faculty Publications
As the telecommunications landscape braces for the post-5G era, this paper embarks on delineating the foundational pillars and pioneering visions that define the trajectory toward 6G wireless communication systems. Recognizing the insatiable demand for higher data rates, enhanced connectivity, and broader network coverage, we unravel the evolution from the existing 5G infrastructure to the nascent 6G framework, setting the stage for transformative advancements anticipated in the 2030s. Our discourse navigates through the intricate architecture of 6G, highlighting the paradigm shifts toward superconvergence, non-IP-based networking protocols, and information-centric networks, all underpinned by a robust 360-degree cybersecurity and privacy-by-engineering design. Delving into …
Similarity May Be Safer: The Effect Of Similarity Between Speech-Based Takeover Request Style And Driver Personality On Self-Driving Takeover Performance, Keer Ma, Jianfeng Wu, Yanxi Lin, Zihan Li, Songyang Guo, Dongfang Jiao, Shihan Yu
Similarity May Be Safer: The Effect Of Similarity Between Speech-Based Takeover Request Style And Driver Personality On Self-Driving Takeover Performance, Keer Ma, Jianfeng Wu, Yanxi Lin, Zihan Li, Songyang Guo, Dongfang Jiao, Shihan Yu
Psychology Faculty Publications
In Level 3 automated driving, it is critical that drivers can rapidly and effectively shift from non-driving related tasks (NDRT) back to the driving task. While previous research has examined the modality, timing, and vocal characteristics of takeover requests (TORs), little is known about how the style of speech-based TORs interacts with drivers’ personality traits. This study conducted a driving simulator experiment with 49 participants using a 2 × 2 within-subjects design. Drawing on the dominant-submissive dimension of personality, we examined the similarity of personality tendencies between speech-based TORs and drivers under takeover scenarios of varying urgency (low: road construction; …
Integration Of Agile Approach Into The Implementation Of The Iso/Sae 21434 On Top Of The V-Model To Enable Continuous Secure-By-Design Automotive Cybersecurity Development, Pooja Patil
Master's Theses and Doctoral Dissertations
The rapid evolution of technology is revolutionizing the automotive industry, with connected and autonomous vehicles at the forefront. These vehicles rely on complex digital ecosystems to enhance safety and efficiency but are increasingly vulnerable to cybersecurity threats. Addressing these challenges requires following robust development methodologies, while complying with cybersecurity standards. This study introduces a framework that merges the widely used agile methodology practices with the ISO/SAE 21434 standard to support secure-by-design automotive product development. Traditional development approaches like the V-model provide structured and linear project phases, but they often lack the flexibility and the ability to adapt to evolving security …
Detection Of Data Leakage And Disruption Of Covert Timing Channel In Secure Drone Communication Using Machine And Deep Learning, Jonathan Walatkiewicz
Detection Of Data Leakage And Disruption Of Covert Timing Channel In Secure Drone Communication Using Machine And Deep Learning, Jonathan Walatkiewicz
Master's Theses and Doctoral Dissertations
The utilization of recreational drones has experienced a substantial increase in both the United States and globally. However, it is noteworthy that most drones, classified as Internet of Things devices, are produced with a limited security lifecycle. This study's findings are of paramount importance, as traditional computing exploits can be applied to drones, designating them as high- value targets. This study examines the detectability and disruptability of covert timing channel traffic in secure drones. The investigation aims to ascertain the effects of multiple interarrival times, distances ranging from 1 to 330 feet, various detection algorithms, and stream sizes between 32-bit …
Motion Planning For A Flexible Modular Raft Robot, Chun-Yi She
Motion Planning For A Flexible Modular Raft Robot, Chun-Yi She
Dartmouth College Master’s Theses
This thesis presents a hierarchical motion planning framework for SoftRafts, a modular and deformable aquatic robot capable of performing locomotion and manipulation tasks on water surfaces. SoftRafts consist of soft and rigid components that enable structural reconfiguration, offering adaptability in unstructured aquatic environments.
To address the complexity of planning in high-dimensional, deformable systems, the proposed method uses a bounding-shape abstraction, specifically, enclosing circles and rectangular bounding boxes to simplify motion planning. These enclosures abstract the robot's overall shape, reducing the high-dimensional planning problem into a lower-dimensional problem. A global planner uses a probabilistic roadmap (PRM) to compute a collision-free path …
Toward General Purpose Llms: From Domain Alignment To Multimodal And Multi-Agent Systems, Thang Nguyen
Toward General Purpose Llms: From Domain Alignment To Multimodal And Multi-Agent Systems, Thang Nguyen
Dartmouth College Master’s Theses
Large Language Models have shown remarkable capabilities, but their generalization across domains, modalities, and collaborative settings remains limited. This work explores how LLMs can be adapted along three dimensions: domain specialization, multimodal processing, and multi-agent reasoning. First, we introduce a reward-guided retrieval mechanism that fine-tunes the retrieval component of a language model using preference-based supervision, improving response relevance in specialized domains. Building on this, we design a multi-agent framework for complex information-seeking tasks, where distinct agents handle query clarification, evidence extraction, and answer synthesis, enabling robust reasoning without additional model training. Extending beyond language, we investigate how LLMs can operate …
Horizontal Infiltration Of Water Through Porous Snow As A Gravity Current, Anthony Cheng
Horizontal Infiltration Of Water Through Porous Snow As A Gravity Current, Anthony Cheng
Dartmouth College Master’s Theses
On the surface of the Greenland ice sheet or around the margins of the Antarctic ice shelf, water infiltrates porous ice. It is important to understand this infiltration process since water populating the pore space of ice directly impacts the density, porosity, and wetness of ice. These properties influence the mechanics and tensile strength of ice, as greater amounts of infiltration result in faster or more widespread deformation events, which may lead to adverse climatic effects such as sea level rise and ocean current disruption. While studies have considered the thermodynamics and fluid mechanics of water vertically percolating through snow …
The Implementation And Miniaturization Of A New Current Source Into The Consolidated Layout Of An Electrical Impedance Tomography Probe With A Novel Approach To Electrode Layout, Katherine M. Bullion
The Implementation And Miniaturization Of A New Current Source Into The Consolidated Layout Of An Electrical Impedance Tomography Probe With A Novel Approach To Electrode Layout, Katherine M. Bullion
Dartmouth College Master’s Theses
Prostate cancer is the most highly diagnosed form of cancer in male subjects in the United States. As a result, over 100,000 radical prostatectomies are performed annually in the US [1]. However, it is currently very difficult for surgeons to confirm that all impacted tissues have been effectively removed from the patient. Positive surgical margins are an independent risk factor for the recurrence of cancer, yet currently there is no method to efficiently, intraoperatively assess the status of surgical margins during a radical prostatectomy. There is a need for a new tool that is small enough to fit into a …
Advanced Nanocomposite-Based Electrochemical Sensor For Ultra-Sensitive Dopamine Detection In Physiological Fluids, Megha Shinde, Gymama Slaughter
Advanced Nanocomposite-Based Electrochemical Sensor For Ultra-Sensitive Dopamine Detection In Physiological Fluids, Megha Shinde, Gymama Slaughter
Center for Bioelectronics Publications
This study presents a novel point-of-care electrochemical sensor for dopamine (DA) detection, featuring a flexible laser-induced graphene (LIG) modified with a unique nanocomposite comprising Nb4C3Tx MXene, polypyrrole (PPy), and iron nanoparticles (FeNPs). The LIG-Nb4C3Tx MXene-PPy-FeNPs is characterized by scanning electron microscopy to confirm the successful surface modification. The electrochemical performance of the fabricated sensor via cyclic voltammetry showed significant electrochemical activity upon Nb4C3Tx MXene-PPy-FeNPs nanocomposite modification of the LIG surface with an increased peak anodic current (Ipa) from 43 μA to 104 μA. The sensor …
Laser-Induced Graphene For Early Disease Detection: A Review, Sri Ramulu Torati, Gymama Slaughter
Laser-Induced Graphene For Early Disease Detection: A Review, Sri Ramulu Torati, Gymama Slaughter
Center for Bioelectronics Publications
Electrochemical biosensors have been instrumental in early disease detection, facilitating effective monitoring and treatment. The emergence of graphene has significantly advanced sensor technology in various fields, including biomedicine, electronics, and energy. In this landscape, laser‐induced graphene (LIG) has emerged as a superior alternative to conventional graphene synthesis methods. Its straightforward fabrication process and compatibility with wearable devices boost its practicality and potential for real‐world applications. This review highlights the transformative potential of LIG in biosensing, showcasing its contributions to the development of next‐generation diagnostic tools for early disease detection. An overview of the LIG synthesis process and its applications in …
Cost-Effective Hierarchical Cobalt Nanostructured Laser-Induced Graphene For Enhanced Uric Acid Detection, Anju Joshi, Gymama Slaughter
Cost-Effective Hierarchical Cobalt Nanostructured Laser-Induced Graphene For Enhanced Uric Acid Detection, Anju Joshi, Gymama Slaughter
Center for Bioelectronics Publications
This study presents an innovative, cost-effective strategy to develop a flexible, enzyme-free biosensor for the sensitive detection of uric acid (UA). Utilizing electrochemically modified cobalt nanostructured on laser-induced graphene electrodes (CoNCs/LIG), this approach surpasses traditional noble metal-based electrocatalysts in sensitivity and affordability. The one-step electrochemical modification method is efficient and straightforward, enabling the uniform deposition of hierarchical flower-like cobalt nanostructures. These structures synergistically enhance the performance of the LIG, resulting in a broad detection range of 5 to 700 µM with a sensitivity of 6.75 µA µM-¹ cm-² and a low detection limit of 3.66 µM for UA. …