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Full-Text Articles in Engineering

Analysis Of Ptfe Radial Lip Seals For Wheel Bearing Applications, Madison Vogt Jan 2025

Analysis Of Ptfe Radial Lip Seals For Wheel Bearing Applications, Madison Vogt

Theses and Dissertations--Mechanical and Aerospace Engineering

A numerical analysis was conducted to investigate the viscoelastic effects of nonlinear materials on the sealing zone and contact pressure distribution of radial lip seals in a conventional geometric topology. The use of nonlinear materials in radial lip seal applications is desirable to improve operation and reliability of rotating machinery due to their high operating temperatures, chemical compatibility, and low friction coefficients. Examples include, but are not limited to, seals within industrial air compressors, turbine engines, aircraft landing systems, chemical processing equipment, and Freon pumps. This work focuses on analyzing the nonlinear viscoelastic response of pure Polytetrafluoroethylene (PTFE) and PTFE …


Simplified Molecular Diagnostics Methods For Environmental Testing Of Pathogens And Other Applications, Mohammad Dehghan Banadaki Jan 2025

Simplified Molecular Diagnostics Methods For Environmental Testing Of Pathogens And Other Applications, Mohammad Dehghan Banadaki

Theses and Dissertations--Mechanical and Aerospace Engineering

Environmental Surveillance (ES) has emerged as a powerful tool to monitor the emergence and persistence of a pathogen within a facility or community using wastewater/water analysis. Over the past four years, implementation of ES has experienced an explosive acceleration, driven by efforts to monitor the spread of SARS-CoV-2, which has made ES a routinely used public health tool in many locations. We can now use ES to measure the emergence/presence/abundance of different viruses (e.g., SARS-CoV-2, influenza, mpox), bacteria (e.g., E. coli, V. cholerae, antibiotic-resistant strains), fungi (e.g., C. auris), and other biological markers indicative of infectious diseases. However, its broad …


Determination And Limitations Of Blocked Forces In Industrial Settings, Matthew Smither Jan 2025

Determination And Limitations Of Blocked Forces In Industrial Settings, Matthew Smither

Theses and Dissertations--Mechanical and Aerospace Engineering

Transfer path analysis methods have been used for decades to determine noise and vibration paths emanating from machinery. In its advent, the machinery source had to be disconnected from the receiver it was attached to in order to gain useful information about each. Further advances in methodology allowed for determining machinery input forces without decoupling them from the structures they were attached to. However, these methods were limited in that the machinery and structures were required to be treated as a system. Thus, any force data obtain was only useful in the configuration it was measured in. Finally, a method …


In-Situ Characterization Of Damage Mechanisms In Ceramic Matrix Composites, Cle' E. Sanchez Jan 2025

In-Situ Characterization Of Damage Mechanisms In Ceramic Matrix Composites, Cle' E. Sanchez

Theses and Dissertations--Mechanical and Aerospace Engineering

Ceramic Matrix Composites have many advantages, attracting the nuclear, aerospace, and automotive industries with their high heat stability, strength, and oxidation resistance. However, challenges are presented when machining these materials due to the brittle properties and complicated microstructure. The objective of this project was to identify damage mechanisms that occur when a CMC is orthogonally machined and the cutting mechanics are observed in-situ, followed by post-cut characterization of the as-machined surface morphology. In this analysis, the main variable is the feed rate, which can influence the damage mechanisms, such as matrix failure (matrix cracking) or fiber failure (pullout). Through this …


In Situ Bourbon Barrel Measurements Of Alcohol By Volume And Liquid Depth Using Borosilicate Glass Probes And Near Infrared Absorption Spectroscopy, Trent T. Reed Jan 2025

In Situ Bourbon Barrel Measurements Of Alcohol By Volume And Liquid Depth Using Borosilicate Glass Probes And Near Infrared Absorption Spectroscopy, Trent T. Reed

Theses and Dissertations--Mechanical and Aerospace Engineering

In pursuit of measuring different variables present in bourbon barrels, absorption spectroscopy was utilized to ensure that different ethanol and water concentrations can be differentiated using a broadband light source and near infrared spectrometer in a simple cuvette-based testing setup. The intensity and absorption plots gathered of different ethanol and water mixtures were then analyzed using proper orthogonal decomposition (POD) to break down the data into modes which represent specific variables of interest, specifically ethanol concentration or alcohol by volume (ABV). The modes were then utilized to find mode constants to represent the data taken from cuvette samples which were …


Numerical Investigation Of Wind Disturbance Around A Multirotor Uav In Crosswind And Vertical Flight, Garrison Page Jan 2025

Numerical Investigation Of Wind Disturbance Around A Multirotor Uav In Crosswind And Vertical Flight, Garrison Page

Theses and Dissertations--Mechanical and Aerospace Engineering

Uncrewed Aerial Vehicles (UAVs) are being increasingly utilized in a wide range of research applications, especially in meteorology. This is due to such factors as their ease of use, maneuverability compared to other forms of data collection, and for rotor- craft, the ability to hover. However, the rotorwash generated by UAVs can introduce significant disturbances, potentially affecting measurement accuracy from sensors. While several studies have investigated the rotorwash of individual UAVs utilizing Particle Image Velocimetry (PIV) and Computational Fluid Dynamics (CFD), there is limited exploration into how different rotor configurations and external wind conditions influence regions of turbulent flow around …


Growth Kinetics And Stability Of Metal Halide Perovskite Nanocrystals: Influence Of Stirring Speed And Water Exposure, You-Lin Huang Jan 2025

Growth Kinetics And Stability Of Metal Halide Perovskite Nanocrystals: Influence Of Stirring Speed And Water Exposure, You-Lin Huang

Theses and Dissertations--Mechanical and Aerospace Engineering

Cesium lead bromide (CsPbBr3) perovskite nanocrystals (NCs) have garnered significant interest due to their exceptional optoelectronic properties, including high photoluminescence quantum yield, tunable bandgap, and excellent carrier dynamics. These attributes make them promising candidates for applications in light-emitting diodes, photovoltaics, and sensing technologies. However, optimizing their synthesis and improving their environmental stability remain critical challenges. This dissertation explores the growth kinetics of CsPbBr3 NCs, focusing on the effects of stirring speed and water exposure on their structural and optical properties.

The synthesis of CsPbBr3 NCs was performed using both mechanochemical (MC) and antisolvent methods, enabling an …


Acoustic Characterization Of A Quadcopter Using A Test Stand, Jared Schmal Jan 2025

Acoustic Characterization Of A Quadcopter Using A Test Stand, Jared Schmal

Theses and Dissertations--Mechanical and Aerospace Engineering

Unmanned Aerial Vehicles (UAVs) with multirotor propulsion and control, commonly called drones or multicopters, generate a complex acoustic field that is not entirely understood. Many components and their interactions contribute to the overall noise level and behavior of the acoustic field. However, performing acoustic measurements on a multicopter in a confined space, such as a small anechoic chamber, can be an extremely difficult and time-consuming process. A test stand was developed to allow for rapid and safe acoustic measurements in a controlled environment. The design, development, and initial measurements are discussed. The performance and acoustic response are assessed to examine …


Analysis Of Closed-Loop Dynamical Systems Using Relu Nns, Pouya Samanipour Jan 2025

Analysis Of Closed-Loop Dynamical Systems Using Relu Nns, Pouya Samanipour

Theses and Dissertations--Mechanical and Aerospace Engineering

This thesis develops a framework for analyzing the stability and invariance properties of closed-loop dynamical systems whose dynamics are derived from neural networks with rectified linear units (ReLUs). The ReLU neural network defines continuous piecewise affine (PWA) functions, which makes them ideal for analysis using polyhedral geometry and optimization techniques. To begin, we introduce two exact algorithms for enumerating polytopic regions of affine behavior induced by ReLU networks: a half-space-based method that checks the feasibility of activation patterns and a geometric vertex-based method. Using these methods, we are able to perform precise region-wise analysis, and these methods serve as the …


In-Situ Informed Modeling And Characterization Of Friction And Built-Up Edge In Machining Of Aerospace Alloys, Avery Hartley Jan 2025

In-Situ Informed Modeling And Characterization Of Friction And Built-Up Edge In Machining Of Aerospace Alloys, Avery Hartley

Theses and Dissertations--Mechanical and Aerospace Engineering

Machining is by no means a new manufacturing process. However, it is separated from other traditional deformation processes by its extreme temperatures and strain rates. The function and life of a multitude of products and mechanical components are dependent on the material properties induced by changing the surface through machining. Furthermore, the tools used within machining are often expensive and material reserves are sparse. The understanding the mechanics of the machining process, especially related to the friction of the tool and workpiece, helps to further the life of tools and parts to minimize economic and environmental impact.

Current friction modeling …


Engineering A Novel Solvent Regenerator That Leverages Electrochemically Induced Ph Swings For Direct Air Capture And Hydrogen Generation, Emmanuel Aluhunmile Ohiomoba Jan 2025

Engineering A Novel Solvent Regenerator That Leverages Electrochemically Induced Ph Swings For Direct Air Capture And Hydrogen Generation, Emmanuel Aluhunmile Ohiomoba

Theses and Dissertations--Mechanical and Aerospace Engineering

Direct Air Capture (DAC) is considered to be a key component for achieving global net-negative emissions. However, to capture CO2 at the low concentrations in the atmosphere requires materials with high affinity for CO2. This makes the solvent-based chemical approach for DAC more applicable compared to physical approaches. Nonetheless, regenerating the capture solvent presents a significant challenge due to high heat requirements for thermal decomposition of carbonates. Leveraging electrochemical principles provides an opportunity to simplify the regeneration process, thus, this work focuses on engineering an electrochemical solvent regenerator for recovering alkaline solvents for DAC, with co-production of …


Machining-Induced Residual Stress Modeling Using Physics-Informed Neural Networks, Md Mehedi Hasan Jan 2025

Machining-Induced Residual Stress Modeling Using Physics-Informed Neural Networks, Md Mehedi Hasan

Theses and Dissertations--Mechanical and Aerospace Engineering

Process-induced residual stress (RS) plays a critical role in determining the structural integrity, fatigue life, corrosion resistance, and dimensional stability of manufactured components. Tensile residual stress can be harmful to the machined workpiece by lowering fatigue strength, while compressive residual stress helps to prevent such issues. Therefore, accurate prediction and control of machining-induced residual stresses are essential for optimizing manufacturing processes and enhancing component performance. However, existing modeling approaches—empirical, analytical, and numerical—often have limited predictive accuracy, demand extensive calibration, or involve high computational costs. Traditional finite element analysis (FEA) provides modeling insights but is constrained by its high computational cost …


Scaling Investigations Of Wall-Bounded Turbulent Flow, Nikolay Gustenyov Jan 2025

Scaling Investigations Of Wall-Bounded Turbulent Flow, Nikolay Gustenyov

Theses and Dissertations--Mechanical and Aerospace Engineering

This dissertation investigates the scaling behavior, structural organization, and modeling of turbulence in wall-bounded flows across a wide range of Reynolds numbers and surface conditions. Through high-resolution experimental studies in zero-pressure- gradient turbulent boundary layers and pipe flows (2000 < Reτ < 38 200), the wall- dependence of turbulent length scales is examined with a focus on both small-scale dissipative motions and large-scale structures. When external intermittency is properly accounted for, dissipative motions are shown to obey inner scaling even in outer- scaled regions, while large-scale motions exhibit outer scaling behavior deep into the inner region. These findings are consistent across internal (pipe) and external (boundary layer) flows and are reflected in distinct features of the longitudinal wavenumber spectrum.

The dissertation also explores the development of a turbulent boundary layer transitioning from a smooth solid wall to a liquid surface. An internal boundary layer forms in response to stochastic surface waves, resulting in increased turbulence intensity and displaced momentum relative to solid-wall cases. Near the liquid surface, turbulence generation aligns with wavenumbers corresponding to the surface waves, introducing distinct small-scale …


Development Of An Immersed Boundary Method-Wall Modeled Large Eddy Simulation Approach For Incompressible Flows And Aeroacoustic Predictions, John C. Higgins Jan 2025

Development Of An Immersed Boundary Method-Wall Modeled Large Eddy Simulation Approach For Incompressible Flows And Aeroacoustic Predictions, John C. Higgins

Theses and Dissertations--Mechanical and Aerospace Engineering

The performance capabilities of rotorcraft have improved significantly in the past decade as both manned and unmanned rotorcraft become a larger part of future transportation systems. Private companies as well as various government offices have worked to develop capabilities ranging from transportation/package delivery to intelligence/surveillance to livestock monitoring. Their practicality in both rural and urban areas, however, is questionable due to the significant tonal and broadband noise which is produced by the rotors. Public acceptance of rotorcraft, namely small Unmanned Aerial Vehicles (sUAVs), in transportation systems is an issue largely associated with the noise generation and it's effect on nearby …


Fluid Pathways For Enhanced Mass Transfer In The Micro Regime: Applications In Novel Pumpless Redox Flow Cell And Zinc Finger Protein-Based Dna Detection, Shaikh Al Mahmud Bhuiyan Jan 2025

Fluid Pathways For Enhanced Mass Transfer In The Micro Regime: Applications In Novel Pumpless Redox Flow Cell And Zinc Finger Protein-Based Dna Detection, Shaikh Al Mahmud Bhuiyan

Theses and Dissertations--Mechanical and Aerospace Engineering

Precise fluid transport through microscale geometries can help optimize electrochemical and biochemical processes by maximizing the mass transfer rate of reactants. By introducing intricate structural features inside microchannels, it is possible to manipulate the fluid motion and direct the flow towards any surface of interest. In this study, we have demonstrated that rationally designed fluid pathways can improve the performance of electrochemical and biochemical systems.

The emergence of additive manufacturing has enabled rapid fabrication of robust structures with intricate features to guide fluid motion. However, their application in nonaqueous electrochemical systems has been limited due to their interaction with organic …


Direct Numerical Simulation Of Pulsating Flow In Curved Pipes: Insights Into Aortic Dissection In Humans, Gokul Anugrah Gopakumar Jan 2025

Direct Numerical Simulation Of Pulsating Flow In Curved Pipes: Insights Into Aortic Dissection In Humans, Gokul Anugrah Gopakumar

Theses and Dissertations--Mechanical and Aerospace Engineering

This dissertation investigates the hemodynamics of pulsating blood flow in curved vessels through direct numerical simulations (DNS), with the overarching aim of uncovering fluid dynamic mechanisms linked to the onset and progression of aortic dissection in humans. The work is structured in two parts: (i) fundamental studies in idealized geometries and (ii) preliminary investigations in patient-specific anatomies. In the first part, curved pipe models representing the aortic arch are used to isolate the effects of pulsation frequency, amplitude ratio, and curvature ratio on transitional and turbulent flow dynamics. The simulations reveal that curvature-driven centrifugal forces shift the peak velocity toward …


High-Altitude Balloon-Launched Uncrewed Aircraft System Measurements Of Atmospheric Turbulence And Qualitative Comparison With Infrasound Microphone Response, Anisa Haghighi Jan 2025

High-Altitude Balloon-Launched Uncrewed Aircraft System Measurements Of Atmospheric Turbulence And Qualitative Comparison With Infrasound Microphone Response, Anisa Haghighi

Theses and Dissertations--Mechanical and Aerospace Engineering

This study explores the use of a balloon-launched uncrewed aircraft system (UAS) to measure atmospheric turbulence in the troposphere and lower stratosphere using both wind velocity measurements and infrasonic acoustic energy. The UAS, a glider configured for autonomous descent along a predefined trajectory, had on board, in situ sensors to capture thermodynamic and kinematic atmospheric parameters. Additionally, it carried an infrasonic microphone to evaluate its potential for remotely detecting clear-air turbulence by capturing infrasonic waves. The system’s performance was assessed over the course of three test flights conducted in New Mexico, USA, in 2021. The descent enabled high-resolution profiling, with …


Simulation-To-Hardware Validation Of Mpc For Binary Thruster 2d Cubesat Control, Aevar Amundinusarson Oefjoerd Jan 2025

Simulation-To-Hardware Validation Of Mpc For Binary Thruster 2d Cubesat Control, Aevar Amundinusarson Oefjoerd

Theses and Dissertations--Mechanical and Aerospace Engineering

Small satellites must execute precise, fuel-limited maneuvers under strict actuation and operational constraints. Model Predictive Control (MPC) is a suitable approach because it optimizes future actions while explicitly enforcing these limits. This work evaluates (1) whether MPC can operate in real time using binary (on/off), asymmetric thrusters, and (2) whether a high-fidelity digital twin can be used to tune and validate the controller prior to hardware testing.

An MPC framework was implemented on a planar satellite prototype that floats on air bearings, operates at 16.7 Hz (60 ms period), and uses eight binary thrusters exhibiting up to 13.2% variation in …


Kentucky Re-Entry Universal Payload System (Krups): Second Atmospheric Re-Entry Flight, Kirsten F. Ford Jan 2025

Kentucky Re-Entry Universal Payload System (Krups): Second Atmospheric Re-Entry Flight, Kirsten F. Ford

Theses and Dissertations--Mechanical and Aerospace Engineering

Kentucky Re-entry Universal Payload System (KRUPS) is a small-scale re-entry capsule developed at the University of Kentucky. The KRUPS project began in 2013 with the aspiration of providing an affordable and repeatable method of collecting data on the re-entry environment. Numerically-based methods used to model re-entry require experimental data to validate their predictions. However, re-entry data is not easily obtained. Flight tests of re-entry vehicles require extensive time and resources, including a substantial financial burden. Alternatively, ground testing is not able to accurately and completely replicate the complex re-entry environment. Thus, there is a need for an inexpensive and accessible …


Influence Of Agrochemical Mixtures On Nitrogen Transformations In Floating Treatment Wetlands, Matthew Russell Jan 2025

Influence Of Agrochemical Mixtures On Nitrogen Transformations In Floating Treatment Wetlands, Matthew Russell

Theses and Dissertations--Biosystems and Agricultural Engineering

Controlling losses of nitrate-N from agricultural fields to ground and surface water environments is one of the most pressing water resources problems today. Increasing levels of nitrate-N pollution in surface and groundwater is a critical threat to human and environmental health across the globe. To mediate nitrate-N losses, natural and constructed wetlands have been increasingly used as nutrient mitigation technologies and strategies. The use of wetlands as a treatment approach for nitrogen in runoff is a common practice in agroecosystems, however, nitrate-N is not the sole constituent present in agricultural runoff, and other biologically active contaminants have the potential to …


Nanopesticide Fate And Transport In Agroecosystems: A Field Study, John C. Stickney Jan 2025

Nanopesticide Fate And Transport In Agroecosystems: A Field Study, John C. Stickney

Theses and Dissertations--Biosystems and Agricultural Engineering

Nanopesticides are an emerging class of pesticides associated with engineered nanoparticles that provide agricultural and environmental benefits. However, nanopesticide fate, transport, and persistence remain poorly understood. As do their potential impacts on the health of agroecosystems and influence on nutrient release. Therefore, this project investigated the fate, transport, and persistence of two widely available nanopesticides, an insecticide, nano-imidacloprid, and a fungicide, nano-copper hydroxide. The fate and transport in runoff water and soils of these nanopesticides, as well as their impacts on nutrients retention, were assessed through a field plot study over 2 growing seasons. Runoff from rainfall events and soil …


Safety Monitoring & Intelligent Power Distribution Systems For Compact Agricultural Equipment, Mason O. Bradley Jan 2025

Safety Monitoring & Intelligent Power Distribution Systems For Compact Agricultural Equipment, Mason O. Bradley

Theses and Dissertations--Biosystems and Agricultural Engineering

The agricultural industry continues to be one of the most dangerous career fields in the United States of America with compact agricultural equipment being a common source for casualties in the industry. The primary focus of this work is to develop new technology that improves operational safety of compact agricultural equipment through the use of low-cost embedded electronics. This work presents the design of three systems in alignment with this goal.

The first system aims to integrate electrical intelligence and passive safety monitoring into the power distribution system of a small piece of agricultural equipment. The system known as the …


Impacts Of Utilizing Reverse Osmosis Concentrate On Mashing, Fermentation, And Water Use In Bourbon Whiskey Production, Ryan C. Sarhan Jan 2025

Impacts Of Utilizing Reverse Osmosis Concentrate On Mashing, Fermentation, And Water Use In Bourbon Whiskey Production, Ryan C. Sarhan

Theses and Dissertations--Biosystems and Agricultural Engineering

This thesis addresses the feasibility of reusing reverse osmosis concentrate (ROC) in the bourbon whiskey fermentation processes. Initial work compared laboratory-scale mashing and fermentation methods, demonstrating that simultaneous saccharification and fermentation reliably reflects industrial-scale processes, with lower complexity and process time. Building upon this, laboratory and distillery-scale experiments demonstrated that reusing ROC in the mashing and fermentation steps does not negatively impact ethanol yields. ROC produced by systems with a water softener was found to significantly increase mash rheology, suggesting a need for potential process adjustments. Softened ROC also altered the production of flavor-influencing volatile congeners. Under worst case conditions, …


Quantifying Sedimentation Dynamics Of Regulated River Backwater Confluences With Low-Order Tributaries, Abby Kathryne Berry Jan 2025

Quantifying Sedimentation Dynamics Of Regulated River Backwater Confluences With Low-Order Tributaries, Abby Kathryne Berry

Theses and Dissertations--Biosystems and Agricultural Engineering

Sediment dynamics in backwater confluences of regulated rivers have received limited study, despite being recognized as hotspots for sedimentation and nutrient attenuation. Development of management and restoration strategies in these landscapes require improved understanding of fluvial geomorphology and sediment transport dynamics due to the alterations in hydraulic regimes and sediment inputs associated with riverine backwaters. The objective of this study was to couple remote sensing, high frequency sensing, and numerical modeling to quantify drivers of erosion and deposition dynamics within regulated river backwater tributary confluences. To meet the objective of this study, data was collected and analyzed from the Fourpole …


Development Of A Cultivation System For Producing Pure Mycelium Materials From Distillers' Spent Grains, Keya Rani Roy Jan 2025

Development Of A Cultivation System For Producing Pure Mycelium Materials From Distillers' Spent Grains, Keya Rani Roy

Theses and Dissertations--Biosystems and Agricultural Engineering

Stillage is a byproduct of distilleries which is rich in organic matter, minerals, and acidic components. It is commonly used as animal feed and has high potential for use as an alternative substrate for microorganisms. Filamentous fungi are saprophytes that can utilize stillage solids to grow as threadlike mycelium. The structure and composition of the filamentous mycelium has shown promise to produce pure mycelium materials (PMM), which might have many potential applications, for instance as a leather-like material or alternative protein food ingredient. Basidiomycota fungi (including true mushrooms) species are presently used in industry to produce PMM due to the …


Development Of Non-Destructive Methods For The Detection And Quantification Of Gluten Sources In Foods, Adewale Abiola Oloyede Jan 2025

Development Of Non-Destructive Methods For The Detection And Quantification Of Gluten Sources In Foods, Adewale Abiola Oloyede

Theses and Dissertations--Biosystems and Agricultural Engineering

Cross-contamination of food with gluten-rich grains such as wheat, barley, and rye remains a significant challenge in gluten-free food production, posing health risks to individuals with gluten-related disorders. Traditional detection methods are often time-consuming and labor-intensive, highlighting the need for rapid and reliable alternatives. This study investigates the use of hyperspectral imaging (HSI) combined with machine learning (ML) and deep learning (DL) techniques for the detection and quantification of gluten contamination in grain-based foods through three main approaches: (i) classification of gluten source contaminants in gluten-free flour, (ii) quantification of gluten content from wheat, rye, and barley flours, and …


Damping Modulation Of Dampened Kapton Surfaces, Sebastian Esteban Jan 2025

Damping Modulation Of Dampened Kapton Surfaces, Sebastian Esteban

Honors Undergraduate Theses

When droplets are vibrated or disturbed, they can exhibit a complex sloshing motion, an understudied behavior in drop physics. Droplet sloshing involves a complex combination of transverse and longitudinal motion that changes the droplet's effective weight on the surface the droplet is on. Our current understanding stems from preliminary work focusing on a cantilever beam of fixed thickness and variable viscosity of the liquid being sloshed. This investigation will focus on how variable cantilever thickness and constant viscosity for a liquid being sloshed affects the beam's deflection under consistent vibration. It will also investigate how the natural frequency of a …


Integrated Compliant Structure For A Hand Exoskeleton, Tristan R. Koopman Jan 2025

Integrated Compliant Structure For A Hand Exoskeleton, Tristan R. Koopman

Honors Undergraduate Theses

This thesis presents the design and prototyping of a wearable hand exoskeleton that integrates a flexible structural framework to assist with hand movement while maintaining comfort and anatomical conformity. The goal was to create a device that supports tendon-driven actuation through a compliant structure, combining elements of rigidity and flexibility to match the natural geometry and motion of the human hand. Traditional hand exoskeletons often trade off motion for structure or vice versa. This project aims to bridge that gap with a hybrid compliant design that balances flexibility and support. The design process followed an iterative approach involving rapid prototyping …


Fabricating Silver-Ceria Polymer Nanocomposite Scaffolds For Biomedical Therapeutic Applications, Shreya S. Pawar Jan 2025

Fabricating Silver-Ceria Polymer Nanocomposite Scaffolds For Biomedical Therapeutic Applications, Shreya S. Pawar

Honors Undergraduate Theses

Improper healing of bone fractures and limited regeneration of bone following bone tumor resection remain a prevalent complication worldwide. Long-term effects of this include joint instability, limited movement, and arthritis. Bone infections (osteomyelitis), reactive oxygen species (ROS) generation via excessive inflammation, and underlying conditions such as osteoporosis can contribute to suboptimal bone tissue regeneration. ROS accumulation stimulates osteoblast apoptosis, while promoting osteoclast differentiation. These processes inhibit mineralization and osteogenesis. Conventional therapeutics involve the utilization of drugs and bone grafts. However, these approaches pose limitations and can result in subsequent complications. Microbial infections, ROS accumulation, and excessive inflammations are factors that …


High-Performance Computational Kernels For Algorithm-System Co-Design In Machine Learning: Enabling Efficient Gcn Training And Llm Inference Serving., Shakya D. Jayakody Arachchige Jan 2025

High-Performance Computational Kernels For Algorithm-System Co-Design In Machine Learning: Enabling Efficient Gcn Training And Llm Inference Serving., Shakya D. Jayakody Arachchige

Graduate Thesis and Dissertation post-2024

The rapid advancement of machine learning, from Graph Convolutional Networks (GCNs) to transformer-based Large Language Models (LLMs), continues to expose fundamental limitations in memory efficiency, scalability, and system reliability. GCNs are critical for domains such as biomedical modeling, social networks, and recommendation systems, yet their reliance on sparse general matrix–matrix multiplication (SpGEMM) makes them highly sensitive to GPU memory constraints and irregular access patterns. As graph data scales, out-of-core computation becomes inevitable, but existing systems are hindered by I/O bottlenecks and underutilized GPU resources. Our contribution with AIRES demonstrates how algorithm–system co-design can alleviate these challenges: by introducing block-wise data …