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Articles 2941 - 2970 of 4871
Full-Text Articles in Medicine and Health Sciences
A New Knot-Supporting Instrument And Knot Technique For Laparoscopic Surgery, Hasan Börekci̇, Eli̇f Börekci̇, Hakan Ak, Kürşad Zengi̇n, Tugay Atalay, Serhat Tanik
A New Knot-Supporting Instrument And Knot Technique For Laparoscopic Surgery, Hasan Börekci̇, Eli̇f Börekci̇, Hakan Ak, Kürşad Zengi̇n, Tugay Atalay, Serhat Tanik
Turkish Journal of Medical Sciences
We report here an instrument designed by Dr Hasan Börekci that provides support to the knot to facilitate knot tying in laparoscopic procedures. We call the device the 'Börekci knot-supporting instrument' and the technique 'Börekci's knot technique'. Materials and methods: To evaluate the efficacy of this instrument, 17 surgeons performing laparoscopic surgery tied 3 knots using the classical intracorporeal method and then using the intracorporeal knot-supporting instrument. The times required to tie each knot were recorded and compared statistically. Results: Comparing the 2 knotting methods, the time spent tying the knots was shorter with the knot-supporting instrument in all 3 …
Investigation Of Linezolid Resistance In Staphylococcus Epidermidis: First Reported Linezolid Resistant Coagulase Negative Staphylococcus In Turkey, Bariş Yalçin, Mehmet Burak Selek, Bayhan Bektöre, Tuğrul Hoşbul, Mustafa Özyurt
Investigation Of Linezolid Resistance In Staphylococcus Epidermidis: First Reported Linezolid Resistant Coagulase Negative Staphylococcus In Turkey, Bariş Yalçin, Mehmet Burak Selek, Bayhan Bektöre, Tuğrul Hoşbul, Mustafa Özyurt
Turkish Journal of Medical Sciences
No abstract provided.
Folate And Homocysteine Metabolisms And Their Roles In The Biochemical Basis Of Neuropsychiatry, Alpaslan Coşar, Osman Meti̇n İpci̇oğlu, Ömer Özcan, Mustafa Gültepe
Folate And Homocysteine Metabolisms And Their Roles In The Biochemical Basis Of Neuropsychiatry, Alpaslan Coşar, Osman Meti̇n İpci̇oğlu, Ömer Özcan, Mustafa Gültepe
Turkish Journal of Medical Sciences
The term 'one-carbon metabolism' is commonly used to describe 3 separate metabolic processes: folate metabolism, the homocysteine remethylation cycle, and the transsulfuration pathway. Folate metabolism concerns the biochemical reactions in which endogenous and exogenous one-carbon units are transferred to tetrahydrofolates. The remethylation cycle is used for the synthesis of methionine from homocysteine with one-carbon units that come from folate. This methionine is then used for the synthesis of S-adenosyl methionine, which is a general donor of methyl groups for many biochemical reactions in the human body. In the transsulfuration pathway, some amino acids and polypeptides, such as cystathionine, cysteine, and …
The Obesity Prevalence Of The Students Between The Ages Of 5-19 In Kütahya, Mehmet Kaya, Ayli̇n Sayan, Mustafa Bi̇ri̇nci̇, Mevlüt Yildiz, Kami̇l Türkmen
The Obesity Prevalence Of The Students Between The Ages Of 5-19 In Kütahya, Mehmet Kaya, Ayli̇n Sayan, Mustafa Bi̇ri̇nci̇, Mevlüt Yildiz, Kami̇l Türkmen
Turkish Journal of Medical Sciences
To determine the prevalence of obesity among students between the ages of 5 and 19 in Kütahya, and to determine the factors associated with obesity prevalence. Materials and methods: The population in the survey was formed of students between the ages of 5 and 19 in the schools of Kütahya. Within the scope of this survey, obesity was evaluated in accordance with the percentile values indicated in a study on the body weight and height, head circumference, and body mass index reference values of Turkish children that was published in 2008. Results: It was determined that 6.5% of the students …
Serum Amyloid A, Fetuin-A, And Pentraxin-3 Levels In Patients With Ischemic Stroke: Novel Prognostic Biomarkers?, Sevi̇lay Sezer, Fatma Uçar, Ersi̇n Kasim Ulusoy, Serpi̇l Erdoğan, Şule Bi̇len, Cevdet Züngün, Sema Uysal, Haci Kemal Erdemli̇
Serum Amyloid A, Fetuin-A, And Pentraxin-3 Levels In Patients With Ischemic Stroke: Novel Prognostic Biomarkers?, Sevi̇lay Sezer, Fatma Uçar, Ersi̇n Kasim Ulusoy, Serpi̇l Erdoğan, Şule Bi̇len, Cevdet Züngün, Sema Uysal, Haci Kemal Erdemli̇
Turkish Journal of Medical Sciences
Inflammation plays an important role in acute ischemic stroke. In this study we aimed to investigate the relationship between acute ischemic stroke and serum amyloid A, fetuin-A, and pentraxin-3 which are inflammation markers. Materials and methods: We enrolled 52 patients with acute ischemic stroke and 30 sex-matched control subjects in the study. The patients were followed for 3 months. We evaluated the common risk factors, laboratory variables, and neurological examination of stroke patients according to prognosis scales. Results: The median serum amyloid A, fetuin-A, and pentraxin-3 levels in the stroke patients were higher than in control subjects (respectively, P = …
What Is The Best Radiological Method To Predict The Actual Weight Of The Prostate?, Meti̇n Kiliç, Ahmet Tunç Özdemi̇r, Serkan Altinova, Ali̇ Fuat Atmaca, Abdullah Erdem Canda, Mevlana Derya Balbay
What Is The Best Radiological Method To Predict The Actual Weight Of The Prostate?, Meti̇n Kiliç, Ahmet Tunç Özdemi̇r, Serkan Altinova, Ali̇ Fuat Atmaca, Abdullah Erdem Canda, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
We compared the weight of the prostate specimen extracted after radical prostatectomy with preoperatively estimated weights of the prostate by different imaging techniques. Materials and methods: Prostate weights were estimated by transabdominal ultrasonography (TAUS), transrectal ultrasonography (TRUS), and computed tomography (CT) preoperatively before radical prostatectomy. Prostatectomy specimens were weighed postoperatively and the actual prostate weights were calculated. Statistical analyses were done using 95% confidence intervals with repeated measurement analysis of variance and intraclass correlation coefficients. Results: Of the 163 patients enrolled in the study, the mean age was 64.2 ± 6.4 (range: 45 to 76) years. The mean postoperative prostate …
Prognostic Value Of Neutrophil/Lymphocyte Ratio In Patients With Pulmonary Embolism, Umut Yücel Çavuş, Si̇nan Yildirim, Ertan Sönmez, Çağatay Ertan, Özcan Özeke
Prognostic Value Of Neutrophil/Lymphocyte Ratio In Patients With Pulmonary Embolism, Umut Yücel Çavuş, Si̇nan Yildirim, Ertan Sönmez, Çağatay Ertan, Özcan Özeke
Turkish Journal of Medical Sciences
Preliminary evidence suggests that inflammation plays a role in the development and prognosis of pulmonary embolism (PE). We used the neutrophil/lymphocyte ratio (NLR) as a measure of systemic inflammation and investigated its association with PE. Materials and methods: A total of 266 patients who were diagnosed with PE and a control group of 124 age- and sex-matched healthy subjects were included in this study. We further classified the PE patients into 2 groups: those who survived and those who died in the first 30 days. Baseline NLR was measured by dividing neutrophil count to lymphocyte count and was compared between …
Choroidal Thickness In Healthy Turkish Subjects, Erol Coşkun, Seydi̇ Okumuş, Bülent Gürler, Ramazan Yayuspayi, Burak Ören, Erdal Kaydu, Ayşegül Çömez, İbrahi̇m Erbağci
Choroidal Thickness In Healthy Turkish Subjects, Erol Coşkun, Seydi̇ Okumuş, Bülent Gürler, Ramazan Yayuspayi, Burak Ören, Erdal Kaydu, Ayşegül Çömez, İbrahi̇m Erbağci
Turkish Journal of Medical Sciences
To investigate choroidal thickness in healthy Turkish subjects. Materials and methods: Refraction, axial length (AXL) measurement, anterior chamber, and fundus examinations were performed. Eyes that had any retinal or choroidal pathology were excluded from the study. Enhanced-depth imaging optical coherence tomography was used to evaluate choroidal thickness. Results: 139 eyes from 70 subjects were investigated. The mean age, AXL, spherical equivalent refractive error (SE), and subfoveal choroidal thickness (SCT) were 34.7 ± 12.7 years, 23.31 ± 0.91 mm, -0.15 ± 1.64 diopters (D), and 326 ± 60 µm, respectively. A negative correlation was found between SCT and AXL (P = …
The Diagnostic Value Of Ischemia-Modified Albumin In The Diagnosis Of Aortic Pathology, Oğuz Eroğlu, Süha Türkmen, Ahmet Menteşe, Gökalp Altun, Süleyman Türedi̇, Umut Eryi̇ği̇t, Süleyman Caner Karahan, Abdülkadi̇r Gündüz
The Diagnostic Value Of Ischemia-Modified Albumin In The Diagnosis Of Aortic Pathology, Oğuz Eroğlu, Süha Türkmen, Ahmet Menteşe, Gökalp Altun, Süleyman Türedi̇, Umut Eryi̇ği̇t, Süleyman Caner Karahan, Abdülkadi̇r Gündüz
Turkish Journal of Medical Sciences
To investigate the diagnostic value of ischemia-modified albumin (IMA) in the diagnosis of patients with aortic aneurysm. Materials and methods: The study group consisted of 98 patients who presented to our university hospital emergency department with aortic pathology and were definitively diagnosed using spiral tomography. The control group consisted of 101 healthy individuals with similar demographic characteristics. Results: Mean IMA values were 0.89 ± 0.21 absorbance units (ABSU) in the aortic aneurysm group (P < 0.001), 0.70 ± 0.12 ABSU in the aortic dissection group (P < 0.001), 0.98 ± 0.23 ABSU in the aneurysm and dissection group (P < 0.001), 0.84 ± 0.16 ABSU in the aneurysm and rupture group (P < 0.001), and 0.87 ± 0.27 ABSU in the aneurysm, dissection, and rupture group (P < 0.001). Mean IMA value for the subjects in the control group was 0.62 ± 0.17 ABSU. All the differences between the aortic pathology groups' IMA values and those of the control group were statistically significant (P < 0.001). Conclusion: On the basis of the findings from this study, serum IMA levels are higher in patients with aortic pathology compared to healthy individuals. This finding suggests that IMA may help to diagnose aortic pathology, but it requires confirmation by additional clinical studies.
Comparison Of The Effects Of Different Percutaneous Tracheotomy Techniques On Acute Tracheal Trauma, Cengi̇z Beki̇r Demi̇rel, Hacer Haltaş, Hasan Kutluk Pampal, Yusuf Ünal, Berri̇n Işik, Mükerrem Uysal
Comparison Of The Effects Of Different Percutaneous Tracheotomy Techniques On Acute Tracheal Trauma, Cengi̇z Beki̇r Demi̇rel, Hacer Haltaş, Hasan Kutluk Pampal, Yusuf Ünal, Berri̇n Işik, Mükerrem Uysal
Turkish Journal of Medical Sciences
As it can easily be performed at the bedside with minimal morbidity, percutaneous dilatational tracheotomy (PDT) is preferred over surgical tracheotomy. The aim of this study is to compare the effects of different PDT techniques on posterior tracheal wall injury. Materials and methods: The study was conducted at the Gazi University Laparoscopy Training Center after approval was granted by the ethics committee. After sedation with xylazine/ketamine, electrocardiography, peripheral oxygen saturation, and blood pressure were monitored. Propofol was used to achieve the desired level of sedation during the procedure. There were 16 pigs, randomly allocated into 4 groups. Multiple, single, forceps, …
Increasing Resistance Of Nosocomial Acinetobacter Baumannii: Are We Going To Be Defeated?, Tümer Güven, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, Ayşe Kaya Kalem, Fatma Eser, Mehmet Akin Taşyaran
Increasing Resistance Of Nosocomial Acinetobacter Baumannii: Are We Going To Be Defeated?, Tümer Güven, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, Ayşe Kaya Kalem, Fatma Eser, Mehmet Akin Taşyaran
Turkish Journal of Medical Sciences
To investigate the change of the antibiotic resistance profiles of the nosocomial Acinetobacter baumannii isolates in intensive care units (ICUs) between the years 2008 and 2011. Materials and methods: A. baumannii isolates that were responsible for ICU-acquired nosocomial infections between 2008 and 2011 were included in the study. The susceptibility rates of the antibiotics that are mainly used in the treatment of Acinetobacter infections were compared by years. Clinical and Laboratory Standards Institute criteria were used to determine antimicrobial susceptibility. Results: There were 252 infection episodes detected in 229 hospitalized patients in the ICU that were caused by A. baumannii. …
Incidental Parathyroidectomy During Thyroid Surgery: Risk Factors, Incidence, And Outcomes, Bünyami̇ Özoğul, Müfi̇de Nuran Akçay, Abdullah Kisaoğlu, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk, Bülent Aydinli
Incidental Parathyroidectomy During Thyroid Surgery: Risk Factors, Incidence, And Outcomes, Bünyami̇ Özoğul, Müfi̇de Nuran Akçay, Abdullah Kisaoğlu, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk, Bülent Aydinli
Turkish Journal of Medical Sciences
Incidental removal of the parathyroid glands is common in some cases. In this trial, we investigated the risk factors, incidence, and outcomes associated with incidental excision of the parathyroid glands during thyroid surgery. Materials and methods: The records of patients who had undergone thyroid surgery in our department between January 2006 and December 2011 were retrospectively evaluated. Results: A total of 801 patients were enrolled in the trial. The number of incidental parathyroidectomies was determined as 19 (2.3%). Statistical evaluation revealed that sex (P > 0.05) and type of surgical operation (P > 0.05) were not associated with a significant impact on …
Puva Phototherapy-Induced Secondary Amyloidosis In Patients With Mycosis Fungoides: A Rare Adverse Effect Of Phototherapy, Itir Ebru Zemheri̇, Sidika Şeyma Özkanli, İlki̇n Zi̇ndanci, Serkan Şenol, Özge Akbulak, Fi̇li̇z Topaloğlu Demi̇r
Puva Phototherapy-Induced Secondary Amyloidosis In Patients With Mycosis Fungoides: A Rare Adverse Effect Of Phototherapy, Itir Ebru Zemheri̇, Sidika Şeyma Özkanli, İlki̇n Zi̇ndanci, Serkan Şenol, Özge Akbulak, Fi̇li̇z Topaloğlu Demi̇r
Turkish Journal of Medical Sciences
Amyloidosis is a common disorder in adults. Secondary amyloidosis in patients with mycosis fungoides (MF) after photochemotherapy with 8-methoxypsoralen followed by ultraviolet A (PUVA) treatment has not been reported. Our aim is to describe the clinical and histological features of PUVA phototherapy-induced secondary amyloidosis. Materials and methods: Sixty-one patients with MF treated with PUVA phototherapy were analyzed clinically and pathologically and by staining with Congo red and crystal violet. Results: Of 61 patients, 5 met the study criteria. Secondary amyloidosis was detected in 5 patients treated with PUVA. The secondary amyloidosis appeared after a mean of 56 exposures (range: 30-81) …
Acute Q Fever Among Febrile Patients In Zahedan, Southeastern Iran, Maliheh Metanat, Nahid Sepehri Rad, Roya Alavi-Naini, Shahram Shahreki, Batool Sharifi-Mood, Aida Akhavan, Zahra Poormotaseri
Acute Q Fever Among Febrile Patients In Zahedan, Southeastern Iran, Maliheh Metanat, Nahid Sepehri Rad, Roya Alavi-Naini, Shahram Shahreki, Batool Sharifi-Mood, Aida Akhavan, Zahra Poormotaseri
Turkish Journal of Medical Sciences
So far, few studies have been conducted on Q fever in Iran. The objective of this study was to determine the frequency of acute Q fever in febrile patients admitted to Boo-Ali Hospital in Zahedan (southeastern Iran). Materials and methods: In this study, 105 febrile patients suspected of having brucellosis were examined using indirect immunofluorescent assay kit for the detection of Coxiella burnetii IgM and IgG phase antibodies in their serum. Serum with a phase II IgG titer of =>256 and a phase II IgM titer of =>50 was predictive for acute Q fever. Additionally, a 4-fold rise …
Factors Associated With The Pain Catastrophizing Scale And Validation In A Sample Of The Turkish Population, Mustafa Süren, İsmai̇l Okan, Azi̇z Mehmet Gökbakan, Zi̇ya Kaya, Ünal Erkorkmaz, Semi̇h Arici, Serkan Karaman, Mürsel Kahveci̇
Factors Associated With The Pain Catastrophizing Scale And Validation In A Sample Of The Turkish Population, Mustafa Süren, İsmai̇l Okan, Azi̇z Mehmet Gökbakan, Zi̇ya Kaya, Ünal Erkorkmaz, Semi̇h Arici, Serkan Karaman, Mürsel Kahveci̇
Turkish Journal of Medical Sciences
The aim of this study was to validate the Pain Catastrophizing Scale (PCS) in the Turkish population and to investigate its correlation with the demographic and clinical characteristics of patients. Materials and methods: Volunteer patients, who were scheduled for elective surgery and who applied to the Outpatient Clinic of Anesthesiology for preoperative evaluation, were asked to complete a PCS form. The patient's age, sex, educational level, marital status, presence of chronic pain, and American Society of Anesthesiologists score were recorded, and PCS scores and demographic variables were compared statistically. Results: Of the 257 patients enrolled in the study, 136 were …
Bone Mineral Density And Vitamin D Status In Children And Adolescents With Congenital Adrenal Hyperplasia, Fatma Demi̇rel, Özlem Kara, Derya Tepe, İhsan Esen
Bone Mineral Density And Vitamin D Status In Children And Adolescents With Congenital Adrenal Hyperplasia, Fatma Demi̇rel, Özlem Kara, Derya Tepe, İhsan Esen
Turkish Journal of Medical Sciences
To determine the prevalence of and risk factors for decreased bone mineral density (BMD) and vitamin D deficiency in children and adolescents with congenital adrenal hyperplasia (CAH). Materials and methods: This study was conducted on 30 girls and 22 boys with CAH (age range = 5-20 years) with median age of 12.0 years. BMD values of lumbar vertebras (L1-L4), which were determined by dual-energy X-ray absorptiometry, were used to calculate z-scores according to chronological age. A serum 25-hydroxyvitamin D level of
Epistaxis In Geriatric Patients, Alper Yüksel, Hani̇fi̇ Kurtaran, Ekrem Sai̇d Kankiliç, Nebi̇l Ark, Kadri̇ye Şeri̇fe Uğur, Mehmet Gündüz
Epistaxis In Geriatric Patients, Alper Yüksel, Hani̇fi̇ Kurtaran, Ekrem Sai̇d Kankiliç, Nebi̇l Ark, Kadri̇ye Şeri̇fe Uğur, Mehmet Gündüz
Turkish Journal of Medical Sciences
Epistaxis is a common emergency in otolaryngology. The aim of this study is to analyze the etiology, management, and accompanying disorders of epistaxis in geriatric patients by reviewing the literature Materials and methods: Data of 117 patients 65 years old and older who presented to the Department of Otorhinolaryngology with active epistaxis between 2004 and 2010 were retrospectively reviewed. Records were evaluated for age, sex, accompanying disorders, drug medication, detailed otorhinolaryngological findings, and management of epistaxis. Results: There were 67 women (57.26%) and 50 men (42.74%) with a mean age of 73.51 years (range: 65–90). Ninety-four (80.34%) patients had accompanying …
Indoor Air Quality In Primary Schools In Keçiören, Ankara, Mustafa Alparslan Babayi̇ği̇t, Bi̇lal Bakir, Ömer Faruk Tekbaş, Recai̇ Oğur, Abdullah Kiliç, Serdar Ulus
Indoor Air Quality In Primary Schools In Keçiören, Ankara, Mustafa Alparslan Babayi̇ği̇t, Bi̇lal Bakir, Ömer Faruk Tekbaş, Recai̇ Oğur, Abdullah Kiliç, Serdar Ulus
Turkish Journal of Medical Sciences
To increase the awareness of environmental risk factors by determining the indoor air quality status of primary schools. Materials and methods: Indoor air quality parameters in 172 classrooms of 31 primary schools in Keçiören, Ankara, were examined for the purpose of assessing the levels of air pollutants (CO, CO_2, SO_2, NO_2, and formaldehyde) within primary schools. Results: Schools near heavy traffic had a statistically significant mean average of CO and SO_2 (P < 0.05). The classrooms that had more than 35 students had higher and statistically significant averages of CO_2, SO_2, NO_2, and formaldehyde compared to classrooms that had fewer than 35 students (P < 0.05). Of all classrooms, 29% had 100 CFU/100 mL and higher concentrations of microorganisms, which were not pathogens. Conclusion: Indoor air quality management should continually be maintained in primary schools for the prevention and control of acute and chronic diseases, particularly considering biological and chemical pollution.
Ocular Surface Culture Changes In Patients After Septoplasty, Mahmut Özkiriş, Zeli̇ha Kapusuz Gencer, Çi̇ğdem Kader, Levent Saydam
Ocular Surface Culture Changes In Patients After Septoplasty, Mahmut Özkiriş, Zeli̇ha Kapusuz Gencer, Çi̇ğdem Kader, Levent Saydam
Turkish Journal of Medical Sciences
To investigate the interrelationships between pre- and postoperative microbiological changes by taking samples from both eyes of 40 patients who underwent septoplasty due to septal deviation. Materials and methods: Forty patients diagnosed with septal deviation who underwent a septoplasty operation under general anesthesia were enrolled in this study. The study was conducted on 40 patients who met the inclusion criteria and attended follow-up visits. One day before the operation and 48 h after the operation, cultures were taken individually from the conjunctivas and puncta of both eyes and sent to the microbiology laboratory. Results: Patients who were candidates for nasal …
An Investigation Of Pulmonary Findings Of Crimean-Congo Haemorrhagic Fever Patients, Gülden Bi̇lgi̇n, Çi̇ğdem Ataman Hati̇poğlu, Şeri̇fe Altun, Cemal Bulut, Sami̇ Kinikli, Ali̇ Pekcan Demi̇röz
An Investigation Of Pulmonary Findings Of Crimean-Congo Haemorrhagic Fever Patients, Gülden Bi̇lgi̇n, Çi̇ğdem Ataman Hati̇poğlu, Şeri̇fe Altun, Cemal Bulut, Sami̇ Kinikli, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
Crimean-Congo haemorrhagic fever (CCHF) generally affects many organs. In this study a retrospective evaluation of the pulmonary findings of CCHF patients was made. Materials and methods: The records of patients were retrospectively analysed. For each patient an evaluation was made of age, sex, occupation, place of residence, contact with ticks, smoking history, and pulmonary radiological and laboratory findings. A confirmed diagnosis of CCHF was made on determination by enzyme-linked immunosorbent assay or polymerase chain reaction. Results: Of the 128 patients, 48.4% were female. Symptoms of coughing were determined in 18% of patients, sputum in 4.7%, chest pain in 3.9%, dyspnoea …
Right-Sided Double-Lumen Tubes: Need For Design Improvement And Better Insertion Technique?, Jean S. Bussieres, Jérôme Lemieux, Jacques Somma
Right-Sided Double-Lumen Tubes: Need For Design Improvement And Better Insertion Technique?, Jean S. Bussieres, Jérôme Lemieux, Jacques Somma
Turkish Journal of Medical Sciences
No abstract provided.
Cystatin C As Biomarker Of Contrast-Induced Nephropathy In Pediatric Cardiac Angiography, Osman Özdemi̇r, Ayşe Deni̇z Oğuz, Abdülkadi̇r Eren, Ci̇hat Şanli, Hüsnü Oğuz Söylemezoğlu, Ayşe Banu Çayci
Cystatin C As Biomarker Of Contrast-Induced Nephropathy In Pediatric Cardiac Angiography, Osman Özdemi̇r, Ayşe Deni̇z Oğuz, Abdülkadi̇r Eren, Ci̇hat Şanli, Hüsnü Oğuz Söylemezoğlu, Ayşe Banu Çayci
Turkish Journal of Medical Sciences
The purpose of this study is to find the frequency of contrast-induced nephropathy (CIN) and to show the risk factors in the development of CIN and the diagnostic utility of serum cystatin C (CysC) and serum and urine neutrophil gelatinase-associated lipocalin (NGAL) during childhood following cardiac angiography. Materials and methods: In this prospective study, we studied 46 children with congenital heart disease. The levels of serum creatinine, serum CysC, and serum NGAL were measured at 4, 24, and 48 h, while levels of urine NGAL and urine creatinine were measured at 4 to 8 and 48 h following cardiac angiography. …
Clinical Manifestations, Complications, And Treatment Of Brucellosis: Evaluation Of 72 Cases, Şükran Köse, Süheyla Seri̇n Senger, Gülgün Akkoçlu, Lütfi̇ye Kuzucu, Yildiz Ulu, Gürsel Ersan, Fi̇li̇z Oğuz
Clinical Manifestations, Complications, And Treatment Of Brucellosis: Evaluation Of 72 Cases, Şükran Köse, Süheyla Seri̇n Senger, Gülgün Akkoçlu, Lütfi̇ye Kuzucu, Yildiz Ulu, Gürsel Ersan, Fi̇li̇z Oğuz
Turkish Journal of Medical Sciences
Brucellosis is an important disease in developing countries. We aimed to determine the epidemiologic, clinical, and laboratory characteristics of brucellosis, which still has a high morbidity in Turkey. Materials and methods: Seventy-two patients with brucellosis, monitored at our clinic from January 2004 to July 2010, were reviewed retrospectively. Results: The average age was determined to be 44.8 ± 18 years, and 40 of the patients were female (55.6%). The most frequent transmission route was the use of raw milk and dairy products, in 45 of the patients (62.5%). The most frequent complaints were joint pain, high fever, weakness, low back …
Thromboelastography In The Evaluation Of Coagulation Disorders In Patients With Sepsis, Yeli̇z Kiliç, İsmet Topçu, Hamza Bambal, Melek Çi̇vi̇
Thromboelastography In The Evaluation Of Coagulation Disorders In Patients With Sepsis, Yeli̇z Kiliç, İsmet Topçu, Hamza Bambal, Melek Çi̇vi̇
Turkish Journal of Medical Sciences
Unbalanced hemostasis and disseminated intravenous coagulopathy serve as key participants in organ dysfunction and disability. In this study we evaluated the coagulation profiles of patients diagnosed with systemic inflammatory syndrome (SIRS)-sepsis and multiple organ dysfunction syndrome. We also researched coagulation in sepsis by comparing thromboelastography (TEG) data with those of nonsepsis patients to determine the usefulness of the TEG device. Materials and methods: Data were collected from 55 anesthesiology and surgery intensive care unit (ICU) patients: 21 with SIRS-sepsis (Group S) and 34 patients without SIRS-sepsis (Group C). Blood samples were taken upon admission to the ICU (t1) and on …
Epidemiology Of Organophosphate Intoxication And Predictors Of Intermediate Syndrome, Şahi̇n Çolak, Mehmet Özgür Erdoğan, Ahmet Baydin, Mustafa Ahmet Afacan, Celal Kati, Lati̇f Duran
Epidemiology Of Organophosphate Intoxication And Predictors Of Intermediate Syndrome, Şahi̇n Çolak, Mehmet Özgür Erdoğan, Ahmet Baydin, Mustafa Ahmet Afacan, Celal Kati, Lati̇f Duran
Turkish Journal of Medical Sciences
To evaluate the usefulness of plasma glucose and serum cholinesterase levels as predictors of organophosphate-induced intermediate syndrome. Materials and methods: Seventy-one organophosphate poisoning patients who were admitted to our emergency department during a 4-year period were evaluated retrospectively. Four patients were excluded from the study due to a lack of medical records. Categorical variables were analyzed using the chi-square test and nonparametric variables were analyzed using the Mann-Whitney U test. Results: Thirty-five (52.2%) patients were male and 32(47.8%) were female. Patients had a mean age of 39.4 ± 15.9 years and 70.1% of the patients were married. Oral intake (68.7%) …
Efficacy Of Resuscitation With Intralipid In A Levobupivacaine-Induced Cardiac Arrest Model, Murat Karcioğlu, Kasim Tuzcu, Fati̇h Sefi̇l, Işil Davarci, Suzan Aydin, Ali̇ Sari, Akin Aydoğan, Rai̇f Özden
Efficacy Of Resuscitation With Intralipid In A Levobupivacaine-Induced Cardiac Arrest Model, Murat Karcioğlu, Kasim Tuzcu, Fati̇h Sefi̇l, Işil Davarci, Suzan Aydin, Ali̇ Sari, Akin Aydoğan, Rai̇f Özden
Turkish Journal of Medical Sciences
Cardiac toxicity due to the administration of local anesthetics may be fatal. In this study, we evaluated the efficacy of a 20% lipid solution combined with epinephrine in a levobupivacaine-induced cardiac arrest model. Materials and methods: A total of 14 New Zealand rabbits were sedated and mechanically ventilated. Asystole was induced with intravenous levobupivacaine injection. The rabbits were randomized into groups receiving the same volume of either 0.9% saline (CR group) or a 20% lipid solution (LE group) along with a 100 µg/kg epinephrine bolus, which were administered immediately upon asystole. Standard advanced cardiac life support protocols were performed. Results: …
The Expression Of Egfr, Cerbb2, P16, And P53 And Their Relationship With Conventional Parameters In Squamous Cell Carcinoma Of The Larynx, Hülya Şi̇mşek, Ünsal Han, Bi̇nnur Önal, Gülçi̇n Şi̇mşek
The Expression Of Egfr, Cerbb2, P16, And P53 And Their Relationship With Conventional Parameters In Squamous Cell Carcinoma Of The Larynx, Hülya Şi̇mşek, Ünsal Han, Bi̇nnur Önal, Gülçi̇n Şi̇mşek
Turkish Journal of Medical Sciences
To investigate the expression of epidermal growth factor receptor¬-HER1 (EGFR), cerbB2 (HER2), p16, and p53, as well as the relationship of the expression of these genes with conventional parameters in squamous cell carcinoma (SCC) of the larynx. Materials and methods: Samples from 92 cases of diagnosed laryngeal SCC between 2001 and 2011 from the Pathology Department of Ministry of Health Ankara Dışkapı Yıldırım Beyazıt Teaching & Research Hospital were studied by immunohistochemistry using EGFR, cerbB2, p16, and p53 antibodies. Results: An increase in the TNM stage and pathological tumor size status correlated with an increase in EGFR and cerbB2 expression. …
Immunohistochemical Investigation Of Galectin-3 In The Skin Of Mice Applied With Origanum Hypericifolium Essential Oil And Irradiated With Ultraviolet B, Pinar İli̇, Nazan Keski̇n
Immunohistochemical Investigation Of Galectin-3 In The Skin Of Mice Applied With Origanum Hypericifolium Essential Oil And Irradiated With Ultraviolet B, Pinar İli̇, Nazan Keski̇n
Turkish Journal of Medical Sciences
To demonstrate galectin-3-immunoreactivity in the undiluted essential oil of Origanum hypericifolium when applied to the ultraviolet B (UVB) irradiated skin of mice. Materials and methods: Female BALB/c mice were allocated to 4 groups, each comprising 6 mice (Group 1: control; Group 2: UVB irradiated control; Group 3: undiluted O. hypericifolium essential oil applied; Group 4: undiluted O. hypericifolium essential oil applied before UVB irradiation). One week prior to UVB irradiation, the undiluted O. hypericifolium essential oil was applied to the shaved dorsal skin of mice 3 times a week. Subsequently, the mice were irradiated 3 times per week with UVB …
Comparison Of Cutaneous Mastocytosis With Onset In Children And Adults, Serap Güneş Bi̇lgi̇li̇, Ayşe Serap Karadağ, Zennure Takci, Ömer Çalka, Mustafa Kösem
Comparison Of Cutaneous Mastocytosis With Onset In Children And Adults, Serap Güneş Bi̇lgi̇li̇, Ayşe Serap Karadağ, Zennure Takci, Ömer Çalka, Mustafa Kösem
Turkish Journal of Medical Sciences
Mastocytosis is a heterogeneous group of diseases characterized by the abnormal infiltration of mast cells in the skin and sometimes other organs. This study aimed to compare the demographic, clinical, and histopathological findings of cutaneous mastocytosis with onset in children and in adults. Materials and methods: Patients diagnosed with cutaneous mastocytosis in 2 different dermatology clinics between 2007 and 2011 were included in the study. Demographic characteristics of the patients as well as localization and type of the cutaneous lesions, presence of symptoms, Darier's sign, family history, systemic involvement, and histopathological evaluations were retrospectively examined. Results: Out of the 30 …
Effects Of Linoleic Acid On Generalized Convulsive And Nonconvulsive Epileptic Seizures, Fati̇h Eki̇ci̇, Gönül Gürol, Nurbay Ateş
Effects Of Linoleic Acid On Generalized Convulsive And Nonconvulsive Epileptic Seizures, Fati̇h Eki̇ci̇, Gönül Gürol, Nurbay Ateş
Turkish Journal of Medical Sciences
To comparatively investigate the effects of linoleic acid on convulsive and nonconvulsive epileptic seizures. Materials and methods: Rats were divided into 3 groups: convulsive epileptic rats receiving only pentylentetrazole (PTZ) injections (group 1), convulsive epileptic rats receiving PTZ and linoleic acid (group 2), and Wistar Albino Glaxo rats from Rijswijk with genetic absence epilepsy receiving linoleic acid (group 3). The duration and severity of convulsive activity were determined in groups in which convulsive seizures were induced by PTZ. In group 3, intravenous linoleic acid was administered after 1-h baseline electroencephalography (EEG) recordings. The EEG recordings were analyzed. Results: When groups …