Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- COVID-19 (110)
- Children (97)
- Oxidative stress (90)
- Inflammation (65)
- Rat (62)
-
- Mortality (59)
- Treatment (57)
- Turkey (57)
- Breast cancer (51)
- Prognosis (51)
- Pregnancy (49)
- Apoptosis (47)
- Prevalence (47)
- Magnetic resonance imaging (46)
- Obesity (46)
- Diabetes mellitus (37)
- Quality of life (36)
- Risk factors (36)
- Diagnosis (34)
- Nitric oxide (32)
- Ultrasonography (32)
- Rheumatoid arthritis (31)
- Epidemiology (30)
- Asthma (29)
- Hypertension (29)
- Reliability (29)
- Child (28)
- Validity (28)
- Depression (26)
- Diabetes (26)
- Publication Year
Articles 4861 - 4871 of 4871
Full-Text Articles in Medicine and Health Sciences
The Effect Of Diphtheria Toxin On Nitric Oxideinduction From Raw264.7 Murine Macrophages, Cemalettin Aybay, Gülnur Tarhan, Turgut İmi̇r, Başak Kayhan
The Effect Of Diphtheria Toxin On Nitric Oxideinduction From Raw264.7 Murine Macrophages, Cemalettin Aybay, Gülnur Tarhan, Turgut İmi̇r, Başak Kayhan
Turkish Journal of Medical Sciences
In this study the effect of diphtheria toxin (DT) on nitric oxide (NO) production from RAW 264.7 murine macrophages was investigated. Griess reagent was used to determine NO production by measuring nitrite levels in the culture supernatants. Corynebacterium diphtheriae G12/6 strain-produced DT (Limes flocculation activity and immunodiffusion assays were positive) demonstrated a dose-dependent effect on RAW 264.7 macrophages to induce NO production. L-NAME, an L-arginine analogue, inhibited NO production from DT-stimulated RAW 264.7 macrophages. At the given concentrations of DT, lipopolysaccharide (LPS or endotoxin)-induced NO production from RAW 264.7 macrophages was also inhibited. RAW 264.7 macrophage cells, incubated with various …
Teratogenic Effects And The Role In The Etiologyof Atopic Diseases Of Erythrosine(Fd&C Red No.3), Onur K. Uysal, Erinç Aral
Teratogenic Effects And The Role In The Etiologyof Atopic Diseases Of Erythrosine(Fd&C Red No.3), Onur K. Uysal, Erinç Aral
Turkish Journal of Medical Sciences
Erythrosine (FD&C Red No.3, di sodium salt of 2,4,5,7-tetra-iodofluorescein); is used extensively as a colour additive in foods, drugs and cosmetics. Previous studies have shown that some of the food additives, depending on their long-term and short-term use, have potential carcinogenic, toxic and teratogenic effects. In Turkey this colourant has temporary permission of use until studies are completed about it. In addition food colours may cause allergic reactioins due to food intolerance. In our study 17 pregnant rats are divided into two groups: control and erythrosine group. 7 Wistar albino rats were administered 5 ml erythrosine (2mg/ml) by gavage at …
Effect Of Acute And Regular Exercise Onantioxidative Enzymes, Tissue Damage Markersand Membran Lipid Peroxidation Of Erythrocytesin Sedentary Students, Recep Aslan, M. Ramazan Şekeroğlu, Mehmet Tarakçioğlu, Fahri Bayiroğlu, İsmail Meral
Effect Of Acute And Regular Exercise Onantioxidative Enzymes, Tissue Damage Markersand Membran Lipid Peroxidation Of Erythrocytesin Sedentary Students, Recep Aslan, M. Ramazan Şekeroğlu, Mehmet Tarakçioğlu, Fahri Bayiroğlu, İsmail Meral
Turkish Journal of Medical Sciences
15 healthy sedentary men, 19-25 years old an did not have any programmed physical activity, were studied. The subjects were asked to run submaximal 15-20 min every day for 5 weeks. Erythrocyte lipid peroxidation, superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) activities and glucose and uric acid levels were determined in blood samples which were taken before and immediately after acute exercise and after the end of 5-week training program. Malonaldialdehyde (MDA), sing of lipid peroxidation, creatin phosphokinase (CK), CK-MB, lactate dehydrigenase (LDH) concentrations increased (p
The Natural Menopause Age Of Women Inerzurum And Factors Influencing The Age Atmenopause, Nesrin Rei̇s, Türkân Pasi̇nli̇oğlu, Şenol Dane
The Natural Menopause Age Of Women Inerzurum And Factors Influencing The Age Atmenopause, Nesrin Rei̇s, Türkân Pasi̇nli̇oğlu, Şenol Dane
Turkish Journal of Medical Sciences
In this study the age at menopause and factors influencing age at menopause were investigated by a questionnaire in 282 women. The mean age of menopause was found to be 45.3 years and ranged from 35 to 54. Positive relationships were found between age at menopause and marital satus, body mass index, gravidity, parity, age at menarche, menstruation and menstruation bleeding period. Whereas negative relationships were found between age at menopause and smoking, age at first birth, abortion status and oral contraceptive use.
A Probable Case Of Men1 Syndrome Presentingwith Intractable Peptic Ulcer Disease Andepisodic Confusion, Şükrü Palanduz, Cemil Taşçioğlu, Nilgün Erten, Mehmet Akif Karan, Kıvanç Çefle, Kerim Güler, Oğuz Öztürk, Şükrü Öztürk
A Probable Case Of Men1 Syndrome Presentingwith Intractable Peptic Ulcer Disease Andepisodic Confusion, Şükrü Palanduz, Cemil Taşçioğlu, Nilgün Erten, Mehmet Akif Karan, Kıvanç Çefle, Kerim Güler, Oğuz Öztürk, Şükrü Öztürk
Turkish Journal of Medical Sciences
No abstract provided.
Neuronal Differentiation In The Cerebral Cortexof The Rat: A Golgi-Cox Study, Necdet Demi̇r, Ramazan Demi̇r
Neuronal Differentiation In The Cerebral Cortexof The Rat: A Golgi-Cox Study, Necdet Demi̇r, Ramazan Demi̇r
Turkish Journal of Medical Sciences
The development of cerebral cortex neurons has been studied in different stages of pre- and postnatal periods of rats. In order to show the neuronal processes, the Golgi-Cox impregnation technique was used. The first neuronal process development was observed in the cranial and caudal poles of the cerebral cortex during the 15th prenatal day and continued spreading from the lateral regions and poles towards the dorsocentral regions of the hemispheres. The cells which showed the first impregnation in the cerebral cortex, were bipolar cells and their bodies were located in the deep regions of the hemisphere wall. Primitive multipolar cells, …
Limited Joint Mobility In 77 Children With Type Idiabetes Mellitus And Correlation To Otherdiabetic Complications, Ayşenur Ökten, Gülay Kaya, Gülay Karagüzel, Yusuf Gedi̇k, Yakup Aslan
Limited Joint Mobility In 77 Children With Type Idiabetes Mellitus And Correlation To Otherdiabetic Complications, Ayşenur Ökten, Gülay Kaya, Gülay Karagüzel, Yusuf Gedi̇k, Yakup Aslan
Turkish Journal of Medical Sciences
We investigated limited joint mobility in 77 patients with type I diabetes mellitus. The patients were also assesed for neuropathy, retinopathy and pulmonary complications. The prevalence of limited joint mobility was 47%. Skin changes were present in 87% of patients with diabetes of more than 5 years' duration. No relationship was found between limited joint mobility and metabolic control, but there was a very strong correlation between limited joint mobility and other diabetic complications such as neuropathy, nephropathy and retinopathy. We did not find any differences in the pulmonary function tests of patients with and without limited joint mobility. We …
Noise Induced Hearing Loss Among Cottontextile And Carpet Mill Workers, Melikşah Ertem, Ersen İlçi̇n, Faruk Meri̇ç
Noise Induced Hearing Loss Among Cottontextile And Carpet Mill Workers, Melikşah Ertem, Ersen İlçi̇n, Faruk Meri̇ç
Turkish Journal of Medical Sciences
In industry increased mechanisation results in increased noise levels. Operation of textile machines carries a high risk of hearing loss. In this study the evaluation of textile worker's noise induced hearing loss was reviewed cross sectionally. The hearing of 260 textile workers exposed to noise levels between 85-95 dB(A) in carpet and cotton textile factories was assessed by means of air and bone conductance audiograms obtained. The subjects were grouped into five hearing categories according to hearing thresholds at 125 to 8000 Hz with Klockhoffs classification. The prevalence of the grade-3 hearing loss was 47.92% and grade 4-5 was 9.21% …
Characterisation Of A Polyclonal Antiserumagaints Ubiquitin And Its Use In The Investigationof Ubiquitin Conjugate Distribution In Normaland Stressed 3t3-Li Cells, İbrahim Pi̇ri̇m
Turkish Journal of Medical Sciences
Antiserum against ubiquitin was used to identify ubiquitin conjugates in 3T3- LI cells, and to investigate changes in the amount and distribution of these conjugates in cells subjected to stress. Stress was induced by incubation with canavanine, an amino acid analogue, and by exposure of cells to temperatures of 43°C (heat shock). SDS-PAGE, followed by immunoblotting, produced no observable change in ubiquitin conjugation with the canavanine as used in this protocol.Heat shock, in a variety of different exposure protocols, appeared to produce an increase in a wide spectrum of ubiquitin conjugates of molecular weight>70kd. The conjugates wereresent in the …
Metabolic Effects Of Isradipine In Normotensiveniddm Patients With Microalbuminuria, Tevfik Sabuncu, Hüseyin Vural, Mahmut Dalmaz, Yaşar Nazligül, Abdurrahim Koçyi̇ği̇t, Özcan Erel, Şenel Avci
Metabolic Effects Of Isradipine In Normotensiveniddm Patients With Microalbuminuria, Tevfik Sabuncu, Hüseyin Vural, Mahmut Dalmaz, Yaşar Nazligül, Abdurrahim Koçyi̇ği̇t, Özcan Erel, Şenel Avci
Turkish Journal of Medical Sciences
The aim of this study was to determine whether isradipine affects microalbuminuria and other biochemical parameters related to glucose and lipid metabolisms. 18 subjects, 40 to 73 years of age, with NIDDM for 0 to 21 years, blood pressure²140/90 mmHg in the absence of antihypertensive treatment, and persistent urinary albumin excretion rate (UAER) 30 to 300 mg/day, received sustained-release (SRO) formulation isradipine at dosages of 5 mg once daily for 3 months. The effects of isradipine on microalbuminuria, fasting plasma glucose, plasma lipids, plasma creatinin, uric acid, C-peptide, insulin, HbA 1c , fructosamine, systolic and diastolic blood pressure and heart …
Changes In Blood Antioxidant Status And Lipidperoxidation Following Distance Running, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Sermet, Mukadder Atmaca, Yüksel Koçyi̇ği̇t
Changes In Blood Antioxidant Status And Lipidperoxidation Following Distance Running, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Sermet, Mukadder Atmaca, Yüksel Koçyi̇ği̇t
Turkish Journal of Medical Sciences
To examine the effects of increased O 2 utilization on blood antioxidant status and lipid peroxidation, ten trained male athletes took part in a 20 km distance race. Venous blood samples were removed before and immediately after completion of the half-marathon. Plasma creatine kinase (CK) activity, an index of muscle damage, increased (p