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Articles 2911 - 2940 of 4871
Full-Text Articles in Medicine and Health Sciences
Evaluation Of Patients With Zygomycosis, Onur Kaya, Sema Alp Çavuş, Özge Turhan, Meltem Işikgöz Taşbakan, Hüsnü Pullukçu, Mustafa Bülent Ertuğrul, Şebnem Şenol, Çi̇ğdem Banu Çeti̇n, Beti̇l Özhak Baysan, Selda Sayin Kutlu, Di̇lek Yeşi̇m Meti̇n, Meltem Avci, Gülşen Mermut, Vi̇ldan Avkan Oğuz, Nur Yapar
Evaluation Of Patients With Zygomycosis, Onur Kaya, Sema Alp Çavuş, Özge Turhan, Meltem Işikgöz Taşbakan, Hüsnü Pullukçu, Mustafa Bülent Ertuğrul, Şebnem Şenol, Çi̇ğdem Banu Çeti̇n, Beti̇l Özhak Baysan, Selda Sayin Kutlu, Di̇lek Yeşi̇m Meti̇n, Meltem Avci, Gülşen Mermut, Vi̇ldan Avkan Oğuz, Nur Yapar
Turkish Journal of Medical Sciences
Zygomycosis is a severe angioinvasive infection caused by Zygomycetes. We retrospectively investigated 16 cases of zygomycosis. Materials and methods: The data of patients, who had been followed between 2004 and 2010 in 8 tertiary-care teaching hospitals, were reviewed. Demographic characteristics, underlying diseases, and clinical signs and symptoms of the patients, as well as diagnostic methods, data obtained by radiological imaging methods, and the therapies, were recorded. Therapeutic approaches, antifungal agents and duration of use, and the characteristics of the cases were identified. Results: The study included 11 female and 5 male subjects. The most common symptoms and clinical signs were …
An Anatomical Study On The Facial Nerve Trunk In Fetus Cadavers, Ahmet Kalaycioğlu, Gülay Yegi̇noğlu, Canan Ertemoğlu Öksüz, Özlem Uzun, Şahi̇ Nur Kalkişim
An Anatomical Study On The Facial Nerve Trunk In Fetus Cadavers, Ahmet Kalaycioğlu, Gülay Yegi̇noğlu, Canan Ertemoğlu Öksüz, Özlem Uzun, Şahi̇ Nur Kalkişim
Turkish Journal of Medical Sciences
Facial nerve paralysis is the most worrying parotid surgery complication. Little attention has been paid to the facial nerve trunk, especially in children. Pathological variations, tumors, and anatomic variations of the facial nerve may cause parotid and facial nerve surgery difficulties. This study describes the facial nerve trunk. Materials and methods: We measured the facial nerve trunk from 8 female and 8 male fetus cadavers aged 21.0 to 35.5 gestational weeks. The locations and positions of the trunks were described. The length of the facial nerve trunk (K) was measured and bifurcation and trifurcation of the trunk was examined. Values …
Resistin Predicts Ischemia In Myocardial Perfusion Scintigraphy, Mustafa Yildirim, Meli̇h Engi̇n Erkan, Muhammet Aşik, Taner Uçgun, Ayşe Yilmaz, Huri̇ Ti̇lla İlçe, Yusuf Aslantaş, Ramazan Memi̇şoğullari, Serkan Bulur, Ahmet Semi̇h Doğan
Resistin Predicts Ischemia In Myocardial Perfusion Scintigraphy, Mustafa Yildirim, Meli̇h Engi̇n Erkan, Muhammet Aşik, Taner Uçgun, Ayşe Yilmaz, Huri̇ Ti̇lla İlçe, Yusuf Aslantaş, Ramazan Memi̇şoğullari, Serkan Bulur, Ahmet Semi̇h Doğan
Turkish Journal of Medical Sciences
Resistin plays a role in the pathogenesis of coronary artery disease and is related to mortality and morbidity through a number of mechanisms. We hypothesize that plasma resistin levels are increased in the presence of ischemia, as measured by GATED single-photon emission computed tomography myocardial perfusion scintigraphy (SPECT MPS), in comparison with nonischemic subjects. Materials and methods: Fasting intravenous blood samples of patients were drawn before a stress test. An ELISA kit was used for the assays. All patients underwent a technetium 99m-sestamibi GATED SPECT MPS study with a 1-day stress-rest protocol. Images were analyzed visually and patients were assessed …
Prevalence Of Blabstractp And Blavim Gene Carriage In Metallo-\Beta-Lactamase-Producing Burn Isolates Of Pseudomonas Aeruginosa In Tehran, Fatemeh Salimi, Fereshteh Eftekhar
Prevalence Of Blabstractp And Blavim Gene Carriage In Metallo-\Beta-Lactamase-Producing Burn Isolates Of Pseudomonas Aeruginosa In Tehran, Fatemeh Salimi, Fereshteh Eftekhar
Turkish Journal of Medical Sciences
To study the prevalence of bla_{VIM} and bla_{IMP} genes in metallo-\beta-lactamase (MBL)-producing burn isolates of Pseudomonas aeruginosa in relation with AmpC and extended-spectrum \beta-lactamase (ESBL) production. Materials and methods: Thirty-two carbapenem-resistant MBL-producing P. aeruginosa burn isolates from Shahid Motahari Burn Hospital in Tehran were employed. Antibiotic susceptibility was determined to 13 antibiotics including imipenem and meropenem by disk diffusion. AmpC and ESBL production was detected by the AmpC disk test and combined disk diffusion assay, respectively. bla_{IMP} and bla_{VIM} gene carriage was shown by polymerase chain reaction and type-specific primers. Results: AmpC production was observed in 81% and ESBL production …
What Is The Effect Of Radioiodine Therapy On Helicobacter Pylori Infection?, Celi̇l Alper Usluoğullari, Eda Demi̇r Önal, Eli̇f Özdemi̇r, Sedat Caner, Osman Ersoy, Reyhan Ersoy, Beki̇r Çakir
What Is The Effect Of Radioiodine Therapy On Helicobacter Pylori Infection?, Celi̇l Alper Usluoğullari, Eda Demi̇r Önal, Eli̇f Özdemi̇r, Sedat Caner, Osman Ersoy, Reyhan Ersoy, Beki̇r Çakir
Turkish Journal of Medical Sciences
Helicobacter pylori is an important human pathogen associated with gastric and duodenal ulcers, gastric mucosa-associated lymphoid tissue lymphoma, and adenocarcinoma. Radioiodine (RAI) treatment plays an important role in the management of differentiated thyroid cancer and primary hyperthyroidism. It is known that during RAI treatment, a considerable amount is absorbed by the stomach as well. In this study we aimed to reveal any therapeutic impact of RAI on H. pylori infections. Materials and methods: Eighty-seven patients who were hospitalized for RAI treatment were consecutively included in this study. Of those, 76 patients had differentiated thyroid cancer and 11 had primary hyperthyroidism. …
Pulsatile Ocular Blood Flow Changes After Panretinal Photocoagulation Treatment In Patients With Proliferative Diabetic Retinopathy, Adem Türk, Cenap Mahmut Esenülkü, Nuretti̇n Akyol, Mehmet Kola, Hi̇dayet Erdöl, Hali̇l İbrahi̇m İmamoğlu
Pulsatile Ocular Blood Flow Changes After Panretinal Photocoagulation Treatment In Patients With Proliferative Diabetic Retinopathy, Adem Türk, Cenap Mahmut Esenülkü, Nuretti̇n Akyol, Mehmet Kola, Hi̇dayet Erdöl, Hali̇l İbrahi̇m İmamoğlu
Turkish Journal of Medical Sciences
To prospectively assess the effects of panretinal photocoagulation (PRP) treatment on pulsatile ocular blood flow (POBF) in patients with proliferative diabetic retinopathy (PDRP). Materials and methods: The study included 40 eyes with PDRP in 27 patients. The PRP treatments were completed in 3 sessions with 3-week intervals. The intraocular pressure (IOP), pulse amplitude (PA), pulse volume (PV), and POBF changes that arose during the sessions were recorded using a blood flow analyzer. Results: The average age of the patients was 57.37 ± 11.14 years. The pre-PRP basal IOP, PA, PV, and POBF values were 20.44 ± 4.13 mmHg, 4.23 ± …
An Unusual Case Of Sclerosing Angiomatoid Nodular Transformation: Radiological And Histopathological Analyses, Meli̇ke Ruşen Meti̇n, Şehnaz Evri̇mler, Nurdan Çay, Hüseyi̇n Çeti̇n
An Unusual Case Of Sclerosing Angiomatoid Nodular Transformation: Radiological And Histopathological Analyses, Meli̇ke Ruşen Meti̇n, Şehnaz Evri̇mler, Nurdan Çay, Hüseyi̇n Çeti̇n
Turkish Journal of Medical Sciences
Sclerosing angiomatoid nodular transformation (SANT) is a rare benign primary vascular lesion of the spleen. Its etiology is still debated. Radiological characteristics are less known, although there are some reports regarding histopathological features of SANT. A 21-year-old male patient was admitted to our hospital with fatigue, weight loss, and abdominal pain for 4 months. Physical examination, complete blood count, and biochemical parameters were unremarkable. Dynamic contrast-enhanced computed tomography (CT) of the abdomen was performed. A heterogeneous well-defined hyperdense nodular lesion 3 cm in diameter was detected during the arterial phase. The detected lesion was seen as isodense with the spleen …
Liver Enzymes, Mean Platelet Volume, And Red Cell Distribution Width In Gestational Diabetes, Serpi̇l Erdoğan, Özhan Özdemi̇r, Halef Okan Doğan, Sevi̇lay Sezer, Cemal Reşat Atalay, Fatma Meri̇ç Yilmaz, Yüksel Koca
Liver Enzymes, Mean Platelet Volume, And Red Cell Distribution Width In Gestational Diabetes, Serpi̇l Erdoğan, Özhan Özdemi̇r, Halef Okan Doğan, Sevi̇lay Sezer, Cemal Reşat Atalay, Fatma Meri̇ç Yilmaz, Yüksel Koca
Turkish Journal of Medical Sciences
To investigate the value of measuring liver enzymes, red cell distribution width (RDW), and mean platelet volume (MPV) in predicting the development of gestational diabetes mellitus (GDM). Materials and methods: The medical records of all pregnant women followed by the obstetrics clinic between January 2010 and November 2012 were systematically evaluated, and patients with a diagnosis of GDM were identified. A total of 68 patients with GDM and 61 healthy controls were included in the study. Results of relevant laboratory parameters were recorded. Results: Out of all the parameters evaluated, mean values for platelet distribution width (PDW) and mean activities …
Detection Of Caga And Vaca Genotypes Of Helicobacter Pylori Isolates From A University Hospital In Ankara Region, Turkey, Ceren Erdoğdu, Zeynep Saribaş, Yakut Akyön Yilmaz
Detection Of Caga And Vaca Genotypes Of Helicobacter Pylori Isolates From A University Hospital In Ankara Region, Turkey, Ceren Erdoğdu, Zeynep Saribaş, Yakut Akyön Yilmaz
Turkish Journal of Medical Sciences
The cagA and vacA profiles and their association with clinical findings show a distinct geographical distribution. In the present study, we aimed to determine the cagA status and vacA allelic subtypes in strains isolated from a university hospital in Ankara and to evaluate their associations with histopathological and endoscopic findings. Materials and methods: A total of 120 H. pylori strains from stock cultures positive for the ureA gene were randomly included in the present study. Of these strains, cagA and vacA allelic subtypes (s1a, s1b, s2, m1, m2) were examined by polymerase chain reaction. Results: Of the 120 strains, 64 …
Diastolic Function Of The Right Ventricle Is Impaired In Experimental Type 2 Diabetic Rat Models, Ya Miao, Wei Zhang, Yuan Zhong, Ming Zhong, Xiao Ma
Diastolic Function Of The Right Ventricle Is Impaired In Experimental Type 2 Diabetic Rat Models, Ya Miao, Wei Zhang, Yuan Zhong, Ming Zhong, Xiao Ma
Turkish Journal of Medical Sciences
To evaluate diastolic function alterations of the right ventricle (RV) by echocardiography in type 2 diabetic rat models. Materials and methods: Male Wistar rats were divided into 2 groups: a control group (n = 8) and a diabetic group (n = 16, with 11 remaining at the end of the experiment), which was fed a high-fat and high-calorie diet and injected with streptozotocin (STZ). RV diastolic functional alteration of rat models was studied by the tricuspid flow Doppler (Ep, Ap, and Ep/Ap) and tissue Doppler imaging (TDI) (Em, Am, and Em/Am) of the lateral tricuspid annulus. RV structural alteration of …
Vitamin C As An Antioxidant: Evaluation Of Its Role On Pulmonary Contusion Experimental Model, Rana Sirmali, Zeynep Gi̇ni̇ş, Mehmet Sirmali, Okan Solak, Bengü Şeli̇man, Yetki̇n Ağaçkiran, Namik Deli̇baş
Vitamin C As An Antioxidant: Evaluation Of Its Role On Pulmonary Contusion Experimental Model, Rana Sirmali, Zeynep Gi̇ni̇ş, Mehmet Sirmali, Okan Solak, Bengü Şeli̇man, Yetki̇n Ağaçkiran, Namik Deli̇baş
Turkish Journal of Medical Sciences
To analyze the protective activity of vitamin C on the lungs by assessing biochemical and histopathological analysis after performing an experimental isolated lung contusion model. Materials and methods: Fifty-four male Sprague-Dawley male rats were used. The rats were randomly separated into 4 groups. Vitamin C (200 mg/kg) was injected intraperitoneally 30 min after trauma. Blood samples were obtained for myeloperoxidase (MPO), glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and catalase (CAT) activities and malondialdehyde (MDA) levels. Blood gas analysis and bronchoalveolar lavage was performed. The lung tissue was also extracted for histopathological examination. Results: The lung contusion enhanced MDA, SOD, CAT, …
Evaluation Of 4 Methods For The Serological Diagnosis Of EpsteinBarr Virus Infection Using An Immunofluorescence Assay As The Reference Method, Mücahi̇de Esra Koçoğlu, Teki̇n Taş, Firat Zafer Mengeloğlu, Şeyda Özsoy, Özlem Bucak
Evaluation Of 4 Methods For The Serological Diagnosis Of EpsteinBarr Virus Infection Using An Immunofluorescence Assay As The Reference Method, Mücahi̇de Esra Koçoğlu, Teki̇n Taş, Firat Zafer Mengeloğlu, Şeyda Özsoy, Özlem Bucak
Turkish Journal of Medical Sciences
Tests specific for VCA IgM, VCA IgG, and EBNA IgG are used to diagnose Epstein-Barr virus (EBV) infections and interpret disease status. The immunofluorescence assay (IFA) is accepted as the gold standard test. The purpose of this study was to evaluate the performance of 4 methods in comparison with IFA. Materials and methods: In total, 101 serum samples were obtained from clinically suspected cases of EBV infection between May 2010 and May 2012 and evaluated by IFA. All serum samples were analyzed by an immunoblot assay, enzyme-linked fluorescent assay (ELFA), enzyme immunoassay (EIA), and immunochromatographic assay (ICA). Results: ELFA and …
Cell Apoptosis And Proliferation In Rat Brains After Intracerebral Hemorrhage: Role Of Wnt/\Beta-Catenin Signaling Pathway, Ling Zhou, Li Deng, Neng Bin Chang, Ling Dou, Chao Xian Yang
Cell Apoptosis And Proliferation In Rat Brains After Intracerebral Hemorrhage: Role Of Wnt/\Beta-Catenin Signaling Pathway, Ling Zhou, Li Deng, Neng Bin Chang, Ling Dou, Chao Xian Yang
Turkish Journal of Medical Sciences
To investigate the role of Wnt/\beta-catenin signaling pathway in cell apoptosis and proliferation in intracerebral hemorrhage (ICH) in rats. Materials and methods: The ICH rats were established by stereotaxic infusion of 50 µL autologous arterial blood into the right striatum. Pathological characteristics of brain tissue was assessed by hematoxylin and eosin and TUNEL staining, and the expressions of proliferating cell nuclear antigen (PCNA) and Wnt3a/\beta-catenin/cyclin D1 were investigated by immunohistochemistry or reverse-transcription polymerase chain reaction. Results: The number of apoptotic cells and PCNA-positive cells kept increasing from the day following the ICH induction and reached a peak on the 3rd …
Investigation Of Serum Macrophage Migration Inhibitor Factor And Monocyte Chemotactic Protein-1 Levels In Irritable Bowel Syndrome, Feti̇ Tülübaş, Mustafa Oran, Rafet Mete, Fi̇li̇z Turan, Ahsen Yilmaz, Zeynep Deni̇z Yildiz, Ahmet Gürel
Investigation Of Serum Macrophage Migration Inhibitor Factor And Monocyte Chemotactic Protein-1 Levels In Irritable Bowel Syndrome, Feti̇ Tülübaş, Mustafa Oran, Rafet Mete, Fi̇li̇z Turan, Ahsen Yilmaz, Zeynep Deni̇z Yildiz, Ahmet Gürel
Turkish Journal of Medical Sciences
Irritable bowel syndrome (IBS), a functional disorder of the bowel, has been thought to result from immune activation. The aim of this study was to evaluate macrophage migration inhibitory factor (MMIF) and monocyte chemotactic protein-1 (MCP-1) levels in IBS patients. Materials and methods: We enrolled 30 IBS patients and 30 healthy controls. The MMIF and MCP-1 levels of all patients and controls were detected using commercial enzyme-linked immunosorbent assay kits. Results: Serum MMIF and MCP-1 levels were markedly higher in IBS patients than in controls. White blood cell, neutrophil, lymphocyte, monocyte, eosinophil, and basophil counts did not differ significantly between …
Association Analyses Of Oxidative Stress, Aerobic Capacity, Daily Physical Activity, And Body Composition Parameters In Patients With Mild To Moderate Copd, Abdurrahman Genç, Kağan Üçok, Ümi̇t Şener, Tülay Koyuncu, Olcay Akar, Sefa Çeli̇k, Mehmet Ünlü
Association Analyses Of Oxidative Stress, Aerobic Capacity, Daily Physical Activity, And Body Composition Parameters In Patients With Mild To Moderate Copd, Abdurrahman Genç, Kağan Üçok, Ümi̇t Şener, Tülay Koyuncu, Olcay Akar, Sefa Çeli̇k, Mehmet Ünlü
Turkish Journal of Medical Sciences
To investigate total oxidant and antioxidant status, maximal aerobic capacity, daily physical activity, pulmonary functions, and body composition changes, as well as the associations among these parameters, in patients with mild to moderate chronic obstructive pulmonary disease (COPD) versus healthy controls. Materials and methods: The study included 30 male patients newly diagnosed with COPD and 30 body mass index-matched, nonsmoker male controls. Maximal aerobic capacity, daily physical activity, total oxidant and antioxidant status, pulmonary function tests, body composition, and anthropometric parameters were measured. Results: Maximal aerobic capacity and total antioxidant values were lower in patients with COPD compared to the …
Effects Of Oral Hormone Replacement Therapy On Mean Platelet Volume In Postmenopausal Women, İkbal Kaygusuz, Serap Aynur Si̇mavli, Ayla Eser, İlknur İnegöl Gümüş, Selcen Yüksel, Zehra Candan İltemi̇r Duvan, Hasan Kafali
Effects Of Oral Hormone Replacement Therapy On Mean Platelet Volume In Postmenopausal Women, İkbal Kaygusuz, Serap Aynur Si̇mavli, Ayla Eser, İlknur İnegöl Gümüş, Selcen Yüksel, Zehra Candan İltemi̇r Duvan, Hasan Kafali
Turkish Journal of Medical Sciences
To examine the effects of hormone replacement therapy (HRT) on mean platelet volume (MPV), lipid profile, and C-reactive protein (CRP) levels in postmenopausal women who have a high risk and incidence of cardiovascular disease. Materials and methods: This study was performed retrospectively. Twenty-seven healthy postmenopausal women received 1 mg estradiol and 2 mg drospirenone orally for 6 months. Twenty-eight healthy postmenopausal women not taking any HRT were admitted to the study as the control population. Results: Time effect (independent from group effect) was statistically significant for the MPV variable (P = 0.025), but there was no significant change in MPV …
Endobronchial Ultrasound-Guided Transbronchial Needle Biopsy For The Diagnosis Of Mediastinal Lymphadenopathy In Patients With Extrathoracic Malignancies, Ayşegül Şentürk, Hati̇ce Kiliç, Habi̇be Hezer, Funda Karaduman Yalçin, Hati̇ce Canan Hasanoğlu
Endobronchial Ultrasound-Guided Transbronchial Needle Biopsy For The Diagnosis Of Mediastinal Lymphadenopathy In Patients With Extrathoracic Malignancies, Ayşegül Şentürk, Hati̇ce Kiliç, Habi̇be Hezer, Funda Karaduman Yalçin, Hati̇ce Canan Hasanoğlu
Turkish Journal of Medical Sciences
Mediastinal lymphadenopathy is common in extrathoracic malignancies and should not always be considered a metastatic lesion. The purpose of this study is to determine the diagnostic value of endobronchial ultrasound-guided transbronchial needle biopsy (EBUS-TBNA) in patients with extrathoracic malignancies. Materials and methods: This study included 54 consecutive patients with extrathoracic malignancies who had suspected mediastinal metastases and had undergone EBUS-TBNA for diagnosis. Results: Using EBUS-TBNA, 27 of 54 patients (50%) were diagnosed with mediastinal metastases. Among patients with mediastinal metastases, 2 (3.7%) had a sarcoid-like reaction, 5 (9.3%) had tuberculosis, and 17 (31.5%) had reactive lymph nodes. In 3 cases …
Effect Of Nodule Size On The Reliability Of Fine-Needle Aspiration Biopsy In Thyroid Nodules, Ali̇ Erkan Uçar, Seyyi̇t Muhsi̇n Sarikaya, Ömer Parlak, Abdussamed Yalçin
Effect Of Nodule Size On The Reliability Of Fine-Needle Aspiration Biopsy In Thyroid Nodules, Ali̇ Erkan Uçar, Seyyi̇t Muhsi̇n Sarikaya, Ömer Parlak, Abdussamed Yalçin
Turkish Journal of Medical Sciences
To investigate the reliability of fine-needle aspiration biopsy (FNAB) in thyroid nodules and benign/malignant discrimination, particularly in large nodules. Materials and methods: A retrospective analysis of 1466 nodules in 402 patients with thyroid nodules who underwent thyroid surgery was made. The pathologic results of the thyroid nodules from preoperative FNAB and postoperative surgical pathology results were compared. Results: FNAB was found to be in accordance with the postoperative pathologic results. A concordance between the FNAB and postoperative pathologic results, particularly in nodules less than 3 cm in size, was detected. However, a similar finding was not detected in nodules larger …
The Role Of Fdg-Pet/Ct In Detecting Unsuspected And Unknown Distant Metastasis In The Initial Staging Of Nsclc, Meti̇n Halaç, Meftune Özhan, Sabi̇re Yilmaz Aksoy, Betül Vatankulu, Anar Aliyev, Sertaç Asa, Ersan Atahan, Muhammet Sai̇t Sağer, Keri̇m Sönmezoğlu
The Role Of Fdg-Pet/Ct In Detecting Unsuspected And Unknown Distant Metastasis In The Initial Staging Of Nsclc, Meti̇n Halaç, Meftune Özhan, Sabi̇re Yilmaz Aksoy, Betül Vatankulu, Anar Aliyev, Sertaç Asa, Ersan Atahan, Muhammet Sai̇t Sağer, Keri̇m Sönmezoğlu
Turkish Journal of Medical Sciences
Our purpose in this retrospective study was to determine the ratio of unexpected [metastases within the coverage area of thorax computed tomography (CT)] and unknown (metastases out of the coverage area of thorax CT) metastases by positron emission tomography/CT (PET/CT) in patients with newly diagnosed non-small cell lung cancer (NSCLC) who had no defined metastatic lesion, and to investigate the contribution of fludeoxyglucose (FDG)-PET/CT in metastasis staging. Materials and methods: A total of 567 patients (489 males and 78 females, mean age 60.9 ± 10.7 years) were enrolled in this study. Among the 567 patients, a total of 156 patients …
Detection The Frequency Of Per-1 Type Extended-Spectrum Ss-Lactamase-Producing Acinetobacter Baumannii Clinical Isolates In Turkey: A Multicenter Study, Gülşah Aşik, Mehmet Özdemi̇r, Muhammet Güzel Kurtoğlu, Server Yağci, Lütfi̇ye Öksüz, Mustafa Gül, Mücahi̇de Esra Koçoğlu, Emel Sesli̇ Çeti̇n, Adnan Seyrek, Mustafa Berktaş, Ahmet Ayyildiz, İhsan Hakki Çi̇ftci̇
Detection The Frequency Of Per-1 Type Extended-Spectrum Ss-Lactamase-Producing Acinetobacter Baumannii Clinical Isolates In Turkey: A Multicenter Study, Gülşah Aşik, Mehmet Özdemi̇r, Muhammet Güzel Kurtoğlu, Server Yağci, Lütfi̇ye Öksüz, Mustafa Gül, Mücahi̇de Esra Koçoğlu, Emel Sesli̇ Çeti̇n, Adnan Seyrek, Mustafa Berktaş, Ahmet Ayyildiz, İhsan Hakki Çi̇ftci̇
Turkish Journal of Medical Sciences
\beta-Lactamases are an important resistance mechanism in Acinetobacter baumannii. Pseudomonas extended-resistance (PER-1) type \beta-lactamase-producing strains have been reported from various geographic locations; however, PER-1 type \beta-lactamases from Turkish hospitals have not been investigated extensively. The aim of this study was to determine the prevalence of PER-1 type \beta-lactamases in A. baumannii isolates in various regions of Turkey. Materials and methods: A total of 763 clinical A. baumannii isolates were collected from 9 university hospitals and 2 state hospitals between 2008 and 2011. Molecular amplification of the OXA-51 gene from the A. baumannii genome was performed in order to verify identification …
The Comparison Of Pandemic H1n1 Igg Levels Between H1n1 Influenza-Vaccinated Healthcare Workers And Unvaccinated Healthcare Workers, Aydin Çi̇fci̇, Özlem Erol, Sali̇h Cesur, Nurkan Aksoy, Üçler Kisa
The Comparison Of Pandemic H1n1 Igg Levels Between H1n1 Influenza-Vaccinated Healthcare Workers And Unvaccinated Healthcare Workers, Aydin Çi̇fci̇, Özlem Erol, Sali̇h Cesur, Nurkan Aksoy, Üçler Kisa
Turkish Journal of Medical Sciences
To compare pandemic H1N1 (pH1N1) IgG antibody levels between healthcare workers who were vaccinated with the pH1N1 influenza vaccine and the unvaccinated healthcare workers who were selected as the control group. Materials and methods: A total of 68 healthcare workers were included in this study. Of those, 53 were adults vaccinated with the H1N1 influenza vaccine and 15 were unvaccinated. Serum samples were parsed and stored at -40 °C until they were examined. Results: Of the total 53 vaccinated healthcare workers, 16 (30.1%) were positive for IgG antibodies (titer > 11), 17 (32.0%) were negative for IgG antibodies (titer < 9), and 20 (37.7%) were borderline (titer: 9-11). Of the 15 unvaccinated healthcare workers, 1 (6.6%) was positive for IgG antibodies, 11 (73.3%) were negative for IgG antibodies, and the remaining 3 (20.0%) had borderline values (P = 0.014, P < 0.05). In both groups, there was no statistically significant difference between IgG-negative, IgG-positive, and borderline subjects in terms of age or sex. Conclusion: The IgG antibody level was higher in the vaccinated healthcare workers than among the unvaccinated healthcare workers.
A General Consideration Of The Importance Of Nutrition For Critically Ill Patients, Ersi̇n Gürkan Dumlu, Mesut Özdedeoğlu, Bi̇rkan Bozkurt, Mehmet Tokaç, Abdussamed Yalçin, Levent Öztürk, Mehmet Kiliç
A General Consideration Of The Importance Of Nutrition For Critically Ill Patients, Ersi̇n Gürkan Dumlu, Mesut Özdedeoğlu, Bi̇rkan Bozkurt, Mehmet Tokaç, Abdussamed Yalçin, Levent Öztürk, Mehmet Kiliç
Turkish Journal of Medical Sciences
Malnutrition is a common medical condition among intensive care unit patients. It should be monitored carefully, since early management of malnutrition can dramatically improve the medical condition of the patients. A general consideration of enteral feeding shows that it is much more useful than parenteral administration, because it is more physiological and poses a lower risk of hyperalimentation. Materials and methods: In this retrospective study, we scanned all files and personal information of patients hospitalized in intensive care units between 2009 and 2012 due to various medical conditions. We evaluated the nutritional status of patients with biochemical parameters that were …
The Increase Of Mean Platelet Volume In Patients With Alzheimer Disease, Emi̇ne Rabi̇a Koç, Ertuğrul Uzar, Yasemi̇n Çirak, Yasemi̇n Parlak Demi̇r, Ati̇lla İlhan
The Increase Of Mean Platelet Volume In Patients With Alzheimer Disease, Emi̇ne Rabi̇a Koç, Ertuğrul Uzar, Yasemi̇n Çirak, Yasemi̇n Parlak Demi̇r, Ati̇lla İlhan
Turkish Journal of Medical Sciences
Vascular risk factors play an important role in the progression of Alzheimer disease (AD). Mean platelet volume (MPV) is a determinant of platelet functionality and increased MPV is associated with an increased risk of vascular inflammation. Here we aimed to examine whether MPV could be used as a marker of vascular damage in AD and to discuss the relation between MPV and other vascular risk factors. Materials and methods: A total of 109 outpatients with AD and 81 healthy controls were included in this study. Diagnosis of AD was made according to defined criteria. The Turkish version of the Mini …
Comparison Of Motor Pattern Of Periodic Limb Movements In Patients With Restless Legs Syndrome And Obstructive Sleep Apnea Syndrome, Murat Gülteki̇n, Sevda İsmai̇loğullari, Murat Aksu
Comparison Of Motor Pattern Of Periodic Limb Movements In Patients With Restless Legs Syndrome And Obstructive Sleep Apnea Syndrome, Murat Gülteki̇n, Sevda İsmai̇loğullari, Murat Aksu
Turkish Journal of Medical Sciences
Periodic limb movements (PLMs) are repetitive and stereotypical movements of the lower extremities that occur during sleep. The purpose of this study was to analyze the leg muscle activity patterns in PLMs seen in restless legs syndrome (RLS) and obstructive sleep apnea syndrome (OSAS). Materials and methods: In this study, 1260 PLMs from 4 patients with RLS and 4 patients with OSAS were analyzed. The spreading and frequency characteristics of the gastrocnemius, medial hamstring, and vastus muscles were examined separately for each muscle in addition to the tibialis anterior muscle already included in the standard polysomnography recording. Results: A greater …
Evaluation Report Of Pediatric Intensive Care Units In Turkey, Benan Bayrakci, Selman Kesi̇ci̇, Tanil Kendi̇rli̇, Gökhan Kalkan, Aydin Sari, Necvan Tokmak, Gökmen Yilmaz, Orkun Baloğlu, İrfan Şencan
Evaluation Report Of Pediatric Intensive Care Units In Turkey, Benan Bayrakci, Selman Kesi̇ci̇, Tanil Kendi̇rli̇, Gökhan Kalkan, Aydin Sari, Necvan Tokmak, Gökmen Yilmaz, Orkun Baloğlu, İrfan Şencan
Turkish Journal of Medical Sciences
To collect data from throughout Turkey in order to facilitate the organization of pediatric intensive care units (PICUs), and to develop short-term immediate action plans and draft long-term strategic plans. Materials and methods: A total of 35 specialists including 17 pediatric critical care (PCC) specialists, 9 PCC fellows in training, and 9 pediatricians working in PICUs evaluated PICUs and their infrastructures, mortality rates, appropriateness of indications for PICU admissions, PICU bed numbers, and utilization of those PICU beds. Results: PICU bed numbers, PCC specialist numbers, and PICU nurse numbers are insufficient in Turkey. The high percentage of inappropriate and inefficient …
An Examination Of The Symptoms Of Anxiety And Parental Attitude In Children With Hemophilia, Osman Abali, Osman Bülent Zülfi̇kar, Sevcan Karakoç Demi̇rkaya, Hamza Ayaydin, Fuat Kircelli̇, Meltap Duman
An Examination Of The Symptoms Of Anxiety And Parental Attitude In Children With Hemophilia, Osman Abali, Osman Bülent Zülfi̇kar, Sevcan Karakoç Demi̇rkaya, Hamza Ayaydin, Fuat Kircelli̇, Meltap Duman
Turkish Journal of Medical Sciences
Hemophilia is an inherited disease with serious repercussions. Psychiatric symptoms are frequently seen in children and adolescents with hemophilia. The aim of this study was to assess symptoms of anxiety in children with hemophilia and parental attitude towards children with hemophilia. Materials and methods: 42 boys were assessed according to child and adolescent psychiatry. Anxiety symptoms and parental attitude were obtained by the State-Trait Anxiety Scale, the Self-Report for Childhood Anxiety Related Disorders (SCARED) and the Parent Attitude Research Instrument (PARI). Results: The mean age was 11.6 ± 2.5 (range; 7-16). State anxiety scores (44.02 ± 6.9) were higher than …
A Comparison Of Dysfunctional Voiding Scores Between Patients With Nocturnal Enuresis And Healthy Children, Özlem Boybeyi̇, Mustafa Kemal Aslan, Emi̇ne Gül Durmuş, İsmai̇l Özmen, Tutku Soyer
A Comparison Of Dysfunctional Voiding Scores Between Patients With Nocturnal Enuresis And Healthy Children, Özlem Boybeyi̇, Mustafa Kemal Aslan, Emi̇ne Gül Durmuş, İsmai̇l Özmen, Tutku Soyer
Turkish Journal of Medical Sciences
To compare dysfunctional voiding symptom scores (DVSSs) between enuretic children and nonenuretic controls and to investigate associated factors that may affect DVSS. Materials and methods: A questionnaire including demographic features, educational status of parents, DVSS questions, and urinary tract infection (UTI) history was designed. A total of 269 patients were included; Group 1 comprised 161 patients with no voiding symptoms and Group 2 comprised 108 patients with nocturnal enuresis (NE). Children with DVSS of greater than 8.5 were suspected to have dysfunctional voiding. The results were evaluated using SPSS 15.0 with Kruskal-Wallis and multivariate logistic regression tests. Results: The median …
Stress Indicators During General Anesthesia With Opioid Analgesics In Children, Biljana Draskovic, Danica Stanic, Anna Uram-Benka, Izabela Fabri
Stress Indicators During General Anesthesia With Opioid Analgesics In Children, Biljana Draskovic, Danica Stanic, Anna Uram-Benka, Izabela Fabri
Turkish Journal of Medical Sciences
To determine which of the applied opioid analgesics brings the most powerful blockade of the stress response with the fewest side effects in children. Materials and methods: This was a prospective, observational clinical study. The study included 150 boys, aged 2-5 years, ASA I, who underwent herniectomy or orchidopexy in day case surgery. The introduction and maintenance of anesthesia was intravenous (propofol, rocuronium, and opioids); airway was maintained by laryngeal mask and ventilation by mixture of oxygen/air. Subjects were divided into 3 groups depending on the applied opioid analgesics (fentanyl, alfentanil, remifentanil). Results: The fentanyl group had the highest blood …
Relationship Between Placental Localisation, Birth Weight, Umbilical Doppler Parameters, And Foetal Sex, Müzeyyen Duran Erdolu, Aydin Köşüş, Nermi̇n Köşüş, Gülçi̇n Di̇lmen, Hasan Kafali
Relationship Between Placental Localisation, Birth Weight, Umbilical Doppler Parameters, And Foetal Sex, Müzeyyen Duran Erdolu, Aydin Köşüş, Nermi̇n Köşüş, Gülçi̇n Di̇lmen, Hasan Kafali
Turkish Journal of Medical Sciences
The aim of this study is to examine the relationship between placental localisation, birth weight, and foetal sex. It also evaluates umbilical artery Doppler parameters and their relationship with placental localisation. Materials and methods: This is a retrospective study of 500 healthy pregnant women who gave birth at our university. All women had undergone a detailed ultrasound and Doppler examination at 20-23 weeks. The ultrasonography results of the patients were examined retrospectively. Foetal biometry, birth weight, and umbilical artery Doppler parameters were recorded and compared according to placental localisation. Results: Birth weight was significantly higher in foetuses with anteriorly located …
Optimizing Individual Treatment Outcomes In Men With Lower Urinary Tract Symptoms Using Storage Subscale Score/Total International Prostate Symptom Score (Ipss) As A New Ipss Ratio, Serkan Altintas, İsmai̇l Cenk Acar, Saadetti̇n Yilmaz Eski̇çorapçi, Ali̇ Ersi̇n Zümrütbaş, Deni̇z Bolat, Ömer Levent Tuncay, Mehmet Zafer Sinik
Optimizing Individual Treatment Outcomes In Men With Lower Urinary Tract Symptoms Using Storage Subscale Score/Total International Prostate Symptom Score (Ipss) As A New Ipss Ratio, Serkan Altintas, İsmai̇l Cenk Acar, Saadetti̇n Yilmaz Eski̇çorapçi, Ali̇ Ersi̇n Zümrütbaş, Deni̇z Bolat, Ömer Levent Tuncay, Mehmet Zafer Sinik
Turkish Journal of Medical Sciences
To evaluate the effects of the storage/total International Prostate Symptom Score (s/T) ratio on the selection and success of medical therapy in men with lower urinary tract symptoms (LUTS). Materials and methods: A total of 54 men (>45 years of age) with moderate or severe LUTS were divided into 2 groups according to the s/T ratio: Group 1 at 0.43. Tamsulosin (0.4 mg to Group 1) and tolterodine ER (4 mg to Group 2) were administered. Patients were evaluated during the 1st and 3rd months of follow-up treatment. Results: Thirty-seven (68.5%) and 17 (31.5%) patients were in Groups 1 …