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Risk Factors Of Congenital Nomalies Of The Kidney And Urinary Tract (Cakut): Exposureto Mobile Phones During Pregnancy, Kübra Çeleğen, Esra Özgül, Zeynep Yeşi̇ldağ, Erdem Yusuf Çamirci, Mehmet Çeleğen, Ayşegül Bükülmez Jan 2024

Risk Factors Of Congenital Nomalies Of The Kidney And Urinary Tract (Cakut): Exposureto Mobile Phones During Pregnancy, Kübra Çeleğen, Esra Özgül, Zeynep Yeşi̇ldağ, Erdem Yusuf Çamirci, Mehmet Çeleğen, Ayşegül Bükülmez

Turkish Journal of Medical Sciences

Congenital anomalies of the kidney and urinary tract(CAKUT) are the leading causes of childhood chronic kidney disease (CKD). The etiology of most of the cases is thought to be multifactorial. In this study, risk factors for CAKUT and the effect of mobile phone-related electromagnetic field (EMF) exposure during pregnancy were investigated.Materials and methods: Fifty-seven cases and 57 healthy controls under 2 years of age were included and their mothers were subjected to a questionnaire. Groups were compared for parents’ demographics, pregestational (chronic disease, body mass index, use of the folic acid supplements) and antenatal variables (gestational disease, weight gain during …


Evaluation Of Clinical And Laboratory Findings In Severe Group Covid-19 Pregnants Without Comorbidity, Fatma Bozkurt, Ömer Çoşkun, Sevda Yeleç, Muhammed Bekçi̇başi, Muhammet Asena, İhsan Bağli Jan 2022

Evaluation Of Clinical And Laboratory Findings In Severe Group Covid-19 Pregnants Without Comorbidity, Fatma Bozkurt, Ömer Çoşkun, Sevda Yeleç, Muhammed Bekçi̇başi, Muhammet Asena, İhsan Bağli

Turkish Journal of Medical Sciences

Background/aim: COVID - 19 disease may be seen with different clinical presentations in pregnant women. Comorbid diseases are important factors affecting the progression of this disease. In this study, we aimed to evaluate the clinical and laboratory findings in pregnant women with COVID - 19 who had no comorbid disease. Material and methods: This retrospective designed study included 217 patients with Covid PCR positive in typically COVID - 19 clinic. The patients were classified into asymptomatic, nonsevere, and severe disease groups. The symptoms, laboratory results, hospital follow- ups and intensive care records of the patients and the findings of new …


Pregnancy And Its Outcomes In Hemodialysis Patients In Turkey, Hamad Dhei̇r, Özkan Güngör, Memnune Sena Ulu, Ebru Gök Oğuz, Necmi̇ Eren, Orçun Altunören, Erhan Tatar, Kadi̇r Gökhan Atilgan, Süleyman Karaköse, İbrahi̇m Güney, Eray Eroğlu, Rüya Mutluay, İlter Bozaci, Alper Alp, Hakan Akdam Jan 2022

Pregnancy And Its Outcomes In Hemodialysis Patients In Turkey, Hamad Dhei̇r, Özkan Güngör, Memnune Sena Ulu, Ebru Gök Oğuz, Necmi̇ Eren, Orçun Altunören, Erhan Tatar, Kadi̇r Gökhan Atilgan, Süleyman Karaköse, İbrahi̇m Güney, Eray Eroğlu, Rüya Mutluay, İlter Bozaci, Alper Alp, Hakan Akdam

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate pregnancy frequency and evaluate the factors affecting live births in hemodialysis (HD) patients. Materials and methods: Female HD patients whose pregnancy was retrospectively reported between January 1, 2014, and December 31, 2019. The duration of HD, primary disease, and the information on whether the pregnancy resulted in abortion, stillbirth, or live birth, whether the HD duration was prolonged after diagnosing the pregnancy and whether it accompanied preeclampsia were recorded. Results: In this study, we reached 9038 HD female patients' data in the study. A total of 235 pregnancies were detected in 145 patients. The …


Pregnancy And Covid-19: Prevention, Vaccination, Therapy, And Beyond, Di̇lek Şahi̇n, Atakan Tanaçan, Sophia Ne Webster, Özlem Moraloğlu Teki̇n Jan 2021

Pregnancy And Covid-19: Prevention, Vaccination, Therapy, And Beyond, Di̇lek Şahi̇n, Atakan Tanaçan, Sophia Ne Webster, Özlem Moraloğlu Teki̇n

Turkish Journal of Medical Sciences

: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has alarmed the world since its first emergence. As pregnancy is characterized by significant changes in cardiovascular, respiratory, endocrine, and immunological systems, there are concerns on issues like the course of disease in pregnant women, safety of medications, route of delivery and risk of obstetric complications. The aim of this review is to summarize the current literature in the management of pregnant women during the COVID-19 pandemic. Although more than 90% of pregnant women with COVID-19 recover without serious morbidity, rapid deterioration of disease and higher …


The Effects Of Salt Consumption Habits On Iodine Status And Thyroid Functions Duringpregnancy, Mahmut Apaydin, Taner Demi̇rci̇, Özden Özdemi̇r Başer, Beki̇r Uçan, Mustafa Özbek, Erman Çakal Jan 2021

The Effects Of Salt Consumption Habits On Iodine Status And Thyroid Functions Duringpregnancy, Mahmut Apaydin, Taner Demi̇rci̇, Özden Özdemi̇r Başer, Beki̇r Uçan, Mustafa Özbek, Erman Çakal

Turkish Journal of Medical Sciences

Background/aim: Iodine is the basic substrate for thyroid hormone synthesis and is vital for the general population and especially pregnant women. Iodine deficiency may cause severe health problems for a foetus. This study aimed to determine the relationship, if any, between iodine level and thyroid function tests, and to determine the relationship between consumption of salt types and its effects on thyroid function tests in the first trimester of pregnancy. Materials and methods: Three hundred and six pregnant women in the first trimester of pregnancy, who had known no thyroid disease history and had not received iodine supportive therapy, were …


Country-Based Report: The Safety Of Omalizumab Treatment In Pregnant Patients Withasthma, Bi̇lun Gemi̇ci̇oğlu, Arzu Di̇dem Yalçin, Yavuz Havlucu, Gül Karakaya, Levent Özdemi̇r, Meti̇n Keren, Sevi̇m Bavbek, Dane Edi̇ger, İpek Kivilcim Oğuzülgen, Zeynep Ferhan Özşeker, Ayşe Arzu Yorgancioğlu Jan 2021

Country-Based Report: The Safety Of Omalizumab Treatment In Pregnant Patients Withasthma, Bi̇lun Gemi̇ci̇oğlu, Arzu Di̇dem Yalçin, Yavuz Havlucu, Gül Karakaya, Levent Özdemi̇r, Meti̇n Keren, Sevi̇m Bavbek, Dane Edi̇ger, İpek Kivilcim Oğuzülgen, Zeynep Ferhan Özşeker, Ayşe Arzu Yorgancioğlu

Turkish Journal of Medical Sciences

Background/aim: We aimed to report outcomes of pregnant patients with asthma under omalizumab treatment and their infants in our country. Materials and methods: Patients with asthma who received omalizumab for at least 6 months and at least one dose during their pregnancy were retrospectively evaluated using a questionnaire regarding their disease and therapy and the health of their infants. Results: Twenty pregnant patients and their 23 infant's data were analyzed. The mean delivery age was 31.8 ± 7.4 years. They received omalizumab for 28.9 ± 21.8 months. Eight (36.4%) patients showed exacerbation of the disease during pregnancy. Forced expiratory volume …


Early Pregnancy After Bariatric Surgery: A Single-Institute Preliminary Experience, Emre Günakan, Hakan Buluş, Yusuf Aytaç Tohma Jan 2020

Early Pregnancy After Bariatric Surgery: A Single-Institute Preliminary Experience, Emre Günakan, Hakan Buluş, Yusuf Aytaç Tohma

Turkish Journal of Medical Sciences

Background/aim: Pregnancy after bariatric surgery is an issue of growing importance with increasing number of women undergoing bariatric surgery. Therefore, in this study we present patients who conceived after sleeve gastrectomy and evaluate the obstetric outcomes. Materials and methods: This retrospective case-control study includes 23 women who conceived after laparoscopic sleeve gastrectomy. Patients were evaluated in two groups according to the number of months between surgery and conception (group 1: ≤12 months; group 2: >12 months). Results: The mean body mass index of patients before surgery and at the time of conception was 46.6 kg/m2 and 29.7 kg/m2, respectively. Nine …


Different Perspectives Of Immunizations During Pregnancy, Gökce Celep, Aysu Duyan Çamurdan, Fatma Nur Baran Aksakal, Osman Fadil Kara Jan 2020

Different Perspectives Of Immunizations During Pregnancy, Gökce Celep, Aysu Duyan Çamurdan, Fatma Nur Baran Aksakal, Osman Fadil Kara

Turkish Journal of Medical Sciences

Background/aim: Pregnant women and infants are at risk of severe lower respiratory tract infections induced by influenza or pertussis. The uptake of both vaccines is poor in spite of proven benefits and safety. We aimed to determine the knowledge and attitude of pregnant women and their primary healthcare providers towards immunization during pregnancy. Materials and methods: This cross-sectional and interventional study was conducted in northern Turkey in 2016. It had 3 different groups including 786 pregnant women, 146 primary healthcare staff, and 97 family practitioners. Different questionnaires were filled by each group. The intervention phase of the study consisted of …


Tetanus Vaccine During Pregnancy: Data Of A Tertiary Hospital In Turkey, Gülşah Dağdevi̇ren, Gökçen Örgül, Aykan Yücel, Di̇lek Şahi̇n Jan 2020

Tetanus Vaccine During Pregnancy: Data Of A Tertiary Hospital In Turkey, Gülşah Dağdevi̇ren, Gökçen Örgül, Aykan Yücel, Di̇lek Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: To evaluate the prevalence of tetanus vaccination in pregnant women and determine the factors affecting the vaccination and barriers to vaccination. Materials and methods: An observational-descriptive study was conducted on 494 women who gave birth at the Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey. Participants were divided into 2 groups, vaccinated and unvaccinated. Sociodemographic characteristics, obstetric history, and prenatal care status were compared between the 2 groups. Results: There were 242 (48.9%) and 252 (51.1%) women in the vaccinated and unvaccinated groups, respectively. The vaccination rate decreased as the number of pregnancies increased (P = …


Retrospective Evaluation Of Anesthetic Techniques In Pregnant Women With Renal Transplantation, Asuman Sargin, Semra Karaman, Şeyda Ceylan Ari, Ali̇ Akdemi̇r, İsmet Hortu Jan 2019

Retrospective Evaluation Of Anesthetic Techniques In Pregnant Women With Renal Transplantation, Asuman Sargin, Semra Karaman, Şeyda Ceylan Ari, Ali̇ Akdemi̇r, İsmet Hortu

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to evaluate anesthesia management in cesarean operation of pregnant women who underwent renal transplantation and the effects on postoperative renal function, retrospectively.Materials and methods: After obtaining the approval of the ethics committee of our hospital, the records of pregnant women who underwent kidney transplantation and cesarean section between 2007 and 2017 were retrospectively analyzed. The patients' demographic data, concomitant disease history, the treatment received, and type of anesthesia were retrospectively evaluated and recorded in the follow-up form.Results: It was found that a total of 47 women who underwent renal transplantation had 47 live …


Immunohistochemical Localization Of Podoplanin In The Placentas Of Hiv-Positivepreeclamptic Women, Onankoy Onyangunga, Jagidesda Moodley, Frederick Odun-Ayo, Thajasvarie Naicker Jan 2018

Immunohistochemical Localization Of Podoplanin In The Placentas Of Hiv-Positivepreeclamptic Women, Onankoy Onyangunga, Jagidesda Moodley, Frederick Odun-Ayo, Thajasvarie Naicker

Turkish Journal of Medical Sciences

Background/aim: Impaired lymphatic function is associated with pathological conditions. The presence of placental lymphatics is still under debate. This study evaluates the placental podoplanin expression in normotensive and preeclamptic women with and without HIV. Materials and methods: Normotensive (n = 60) and preeclamptic (n = 120) pregnant women were stratified into early and late onset preeclampsia and further divided by HIV status. Immunostaining was performed using the podoplanin antibody prior to the morphometric image analysis. Results: Podoplanin was immunolocalized in a reticular-like stroma complex within the exchange and conducting villi. The immunoexpression of podoplanin was significantly upregulated in the exchange …


Factors Influencing The Success Of Cord Blood Collection: A Tertiary Perinatal Medicinecenter's Experience, Atakan Tanaçan, Pinar Yurdakul Mesutoğlu, Fati̇h Aktoz, Gökçen Örgül, Meral Beksaç, Mehmet Si̇nan Beksaç Jan 2018

Factors Influencing The Success Of Cord Blood Collection: A Tertiary Perinatal Medicinecenter's Experience, Atakan Tanaçan, Pinar Yurdakul Mesutoğlu, Fati̇h Aktoz, Gökçen Örgül, Meral Beksaç, Mehmet Si̇nan Beksaç

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the effects of certain maternal, fetal, and umbilical cord blood unit factors on storage and/or discard incidence of collected cord blood units from perinatal medicine patients. Materials and methods: A total of 273 cord blood units collected between January 2011 and December 2016 in the Division of Perinatology of Hacettepe University Hospital were evaluated retrospectively in this study. Results: Of the collected cord blood units, 53.8% (147/273) were stored. Infant birth weight, cord blood unit volume, total nucleated cell count, and CD34+ cell count were statistically significantly different between the eligible and discarded cord …


Comparison Of Percutaneous Nephrostomy And Double J Stent In Symptomatic Pregnancy Hydronephrosis Treatment, Adnan Şi̇mşi̇r, Fuat Kizilay, Mehmet Bülent Semerci̇ Jan 2018

Comparison Of Percutaneous Nephrostomy And Double J Stent In Symptomatic Pregnancy Hydronephrosis Treatment, Adnan Şi̇mşi̇r, Fuat Kizilay, Mehmet Bülent Semerci̇

Turkish Journal of Medical Sciences

Background/aim: We aimed to compare the success rate of percutaneous nephrostomy (PCN) and double J stenting (DJS) in the treatment of symptomatic pregnancy hydronephrosis. Materials and methods: Diagnosis and grading of hydronephrosis were performed by urinary ultrasound (USG) and Doppler mode was used for evaluation of renal arterial resistivity index (RI). Patients were divided into two groups according to the method used for the treatment of hydronephrosis: group A (PCN, n = 38) and group B (DJS, n = 46). A P value < 0.05 was considered signi cant. Results: The number of patients requiring second intervention was higher in group B (P = 0.0018) and time to secondary intervention was signi cantly earlier in group B also (P = 0.0025). e number of tertiary intervention was again higher in group B (5/16 vs. 1/6) and the need for tertiary intervention was higher in patients who underwent DJS implantation as a secondary intervention than those who underwent PCN (5/11 vs. 1/11, P = 0.0012). e time to tertiary intervention was longer in patients with PCN than in those with DJS (P = 0.0048). Conclusion: PCN may be preferred to DJS in symptomatic pregnancy hydronephrosis because it requires fewer re-interventions a er longer times.


Relation Between Foot Pain And Plantar Pressure In Pregnancy, Tuncay Varol, Asli Göker, Eni̇s Cezayi̇rli̇, Serkan Özgür, Ayşe Tuç Yücel Jan 2017

Relation Between Foot Pain And Plantar Pressure In Pregnancy, Tuncay Varol, Asli Göker, Eni̇s Cezayi̇rli̇, Serkan Özgür, Ayşe Tuç Yücel

Turkish Journal of Medical Sciences

Background/aim: Hormonal and structural changes that occur during pregnancy cause alterations in body biomechanics. These alterations reach their peak in the last trimester. Adaptive changes that appear in the foot result in pain in the foot and ankle. Pedobarography is a noninvasive measurement method that can be used to understand the origin of such pain. Materials and methods: One hundred and thirty-one pregnant women who did not have a foot or ankle problem prior to pregnancy volunteered to take part in the study. Pain was quantified by a visual analog scale (VAS). A cut-off value of 2.95 was taken to …


Traditional Practices Of Konya Women During Pregnancy, Birth, The Postpartumperiod, And Newborn Care, Berri̇n Okka, Yasemi̇n Durduran, Nesli̇han Değerli̇ Kodaz Jan 2016

Traditional Practices Of Konya Women During Pregnancy, Birth, The Postpartumperiod, And Newborn Care, Berri̇n Okka, Yasemi̇n Durduran, Nesli̇han Değerli̇ Kodaz

Turkish Journal of Medical Sciences

Background/aim: The purpose of the present study was to identify traditional practices and the extent to which they are practiced by mothers during pregnancy, birth, the postpartum period, and newborn care. Materials and methods: This study was conducted in the city center of Konya (Turkey). Data were collected through questionnaires completed by volunteers. The research sample comprised 450 mothers, all of whom had given birth to at least one live baby. The forms were completed during face-to-face interviews. Results: Some traditional pregnancy practices were followed by 70.7% of the participants. Of the women who performed these practices, 57.4% consciously chose …


Relationship Between Gestational Transient Thyrotoxicosis And Vitamin D, Feri̇t Keri̇m Küçükler, Yasi̇n Şi̇mşek, Ümi̇t Görkem, Berçem Ayçi̇çek Doğan, Serdar Güler Jan 2016

Relationship Between Gestational Transient Thyrotoxicosis And Vitamin D, Feri̇t Keri̇m Küçükler, Yasi̇n Şi̇mşek, Ümi̇t Görkem, Berçem Ayçi̇çek Doğan, Serdar Güler

Turkish Journal of Medical Sciences

Background/aim: Gestational transient thyrotoxicosis (GTT) is a transient, mild hyperthyroidism that occurs early in pregnancy and is due to human chorionic gonadotropin. There is no clear information about why only some pregnant women develop GTT. Previous papers stated that vitamin D plays a role in thyroid functions. We aimed to evaluate the relationship between vitamin D and GTT. Materials and methods: Fifty-three patients diagnosed with GTT at the 6th to 10th weeks of gestation were included in the study (GTT group). Thirty-five pregnant women with normal thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), and free thyroxine (fT4) levels served as a …


Crp, Hba1c, Lipid, And Biochemical Parameters And Their Relation With Maternal Visceral Adipose Tissue And Subcutaneous Fat Tissue Thickness, Müzeyyen Duran, Aydin Köşüş, Nermi̇n Köşüş, Ni̇lgün Turhan Jan 2016

Crp, Hba1c, Lipid, And Biochemical Parameters And Their Relation With Maternal Visceral Adipose Tissue And Subcutaneous Fat Tissue Thickness, Müzeyyen Duran, Aydin Köşüş, Nermi̇n Köşüş, Ni̇lgün Turhan

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to find whether maternal visceral tissue (VAT) or subcutaneous fat tissue (SCFT) thicknesses are associated with CRP, HbA1c, lipid, and biochemical parameters in the first trimester of pregnancy. Materials and methods: Ninety pregnant women were enrolled. Body mass index (BMI), VAT, and SCFT were measured. The best cut-off points for grouping subjects were found to be 4 cm for VAT and 2 cm for SCFT. Venous blood samples were collected. Results: VAT was higher than 4 cm in all cases with high BMIs. High CRP and HbA1c were found in 45.5% and 18.2% …


Fetal Health Locus Of Control In A Sample Of Pregnant Turkish Women, Sevgi̇ Özcan, Veli̇ Duyan Jan 2015

Fetal Health Locus Of Control In A Sample Of Pregnant Turkish Women, Sevgi̇ Özcan, Veli̇ Duyan

Turkish Journal of Medical Sciences

Background/aim: To examine the relationship between sociodemographic and pregnancy features and fetal health locus of control (FHLC) in a sample of pregnant Turkish women. Materials and methods: The study was conducted with 256 pregnant women. Data were collected by demographic questionnaire and the FHLC Scale consisting of 3 components: 1) Internality Scale (FHLC-I), 2) Powerful Others Scale (FHLC-P), and 3) Chances Scale (FHLC-C). Results: The age of marriage was found to have a positive relation with FHLC-I (r = 0.141) and a negative relation with FHLC-C (r = -0.145) (P < 0.05). The age of first pregnancy was found to have a positive relation with FHLC-I (r = 0.127). Those who have a low educational level (r = -0.258) and income (r = -0.149), who are unemployed (r = -2.839), whose number of pregnancies is high (r = 0.152), who get pregnant unplanned (r = 3.839), and who come to their first prenatal examination late (r = -0.142) have a significantly high score of FHLC-C (P


Intrahepatic Cholestasis Of Pregnancy May Lead To Low Birth Weight, İbrahi̇m Uyar, İbrahi̇m Gülhan, Deni̇z Özteki̇n, Cenk Gezer, Atalay Eki̇n, Seçi̇l Karaca Kurtulmuş, Mehmet Özeren Jan 2015

Intrahepatic Cholestasis Of Pregnancy May Lead To Low Birth Weight, İbrahi̇m Uyar, İbrahi̇m Gülhan, Deni̇z Özteki̇n, Cenk Gezer, Atalay Eki̇n, Seçi̇l Karaca Kurtulmuş, Mehmet Özeren

Turkish Journal of Medical Sciences

Background/aim: To evaluate patients hospitalized in our clinic in the last 5 years with the diagnosis of intrahepatic cholestasis of pregnancy (ICP). Materials and methods: One hundred and fifty patients hospitalized with a diagnosis of ICP between January 2008 and May 2013 were evaluated retrospectively and age, week at diagnosis, gestational age at delivery, period between diagnosis and delivery, fetal weight, transaminases, and coagulation parameters were recorded. Patients were divided into groups according to their diagnosis weeks and gravida. Accordingly, patients diagnosed before 32 weeks formed group A (n = 49) and those after 32 weeks formed group B (n …


Effects Of Prenatally Exposed Diclofenac Sodium On Rat Heart Tissue:A Stereological And Histological Study, Fi̇kret Gevrek, Mi̇kai̇l Kara, Murat Çeti̇n Rağbetli̇, Hüseyi̇n Aslan Jan 2015

Effects Of Prenatally Exposed Diclofenac Sodium On Rat Heart Tissue:A Stereological And Histological Study, Fi̇kret Gevrek, Mi̇kai̇l Kara, Murat Çeti̇n Rağbetli̇, Hüseyi̇n Aslan

Turkish Journal of Medical Sciences

Background/aim: Diclofenac sodium (DS) can cross the placental barrier and affect the fetus, and its consumption during pregnancy may cause developmental malformation of embryos. This study investigates the effect of prenatally applied DS on the quantitative morphology of the adult rat heart. Materials and methods: Pregnant rats were divided into three groups (control, sham, and test). The rats in the test group were injected with DS; the control group received physiological saline (1 mL; 1 mg/kg, i.m.) from the 5th to the 20th day of pregnancy; and the rats in the sham group were not injected at all. At the …


Incidence Of Maternal Vitamin D Deficiency In A Region Of Ankara, Turkey: A Preliminary Study, Gökçe Gür, Ayhan Abaci, Adem Yasi̇n Köksoy, Ahmet Anik, Gönül Çatli, Fati̇h Mehmet Kişlal, Kadi̇r Okhan Akin, Nesi̇be Andiran Jan 2014

Incidence Of Maternal Vitamin D Deficiency In A Region Of Ankara, Turkey: A Preliminary Study, Gökçe Gür, Ayhan Abaci, Adem Yasi̇n Köksoy, Ahmet Anik, Gönül Çatli, Fati̇h Mehmet Kişlal, Kadi̇r Okhan Akin, Nesi̇be Andiran

Turkish Journal of Medical Sciences

To evaluate vitamin D levels and risk factors for vitamin D deficiency in healthy newborns and their mothers. Materials and methods: Ninety-nine healthy pregnant women (≥37 weeks of gestation) were enrolled in the study. Previous history of pregnancies and births, nutritional status, multivitamin supplementation, educational status, type of clothing, and the economic level of the family were recorded. Blood samples were drawn from the mothers and the umbilical cord of the newborns to measure serum 25(OH)D3, calcium, phosphorus, and parathormone levels. Results: While vitamin D insufficiency was identified as 62.6% in mothers, it was 58.6% in newborns; on the other …


Evaluation Of Apoptotic Cell Death Following Transient Maternal Hypotension In Fetal Rat Brain: Temporal Pattern Within The First 24 H After Procedure, Si̇bel Bayrak, Bi̇lge Pehli̇vanoğlu, Ayşe Meltem Sevgi̇li̇, Zeynep Di̇cle Balkanci, Hami̇t Özyürek, Pergi̇n Ati̇lla, Ayşe Nur Çakar, Fatma Banu Anlar Jan 2014

Evaluation Of Apoptotic Cell Death Following Transient Maternal Hypotension In Fetal Rat Brain: Temporal Pattern Within The First 24 H After Procedure, Si̇bel Bayrak, Bi̇lge Pehli̇vanoğlu, Ayşe Meltem Sevgi̇li̇, Zeynep Di̇cle Balkanci, Hami̇t Özyürek, Pergi̇n Ati̇lla, Ayşe Nur Çakar, Fatma Banu Anlar

Turkish Journal of Medical Sciences

To explore the effects of maternal transient systemic hypotension on apoptotic neuronal death in an intrauterine fetal rat brain during the first 24 h after induction of hypotension. Materials and methods: A total of 40 pregnant Sprague–Dawley rats were subjected to either transient systemic hypotension produced for 30 min by blood withdrawal via femoral artery catheterization (hypotension group) or sham operation (control group) on day 15. Two randomly selected fetuses were taken from each rat at 0, 6, 12, and 24 h after the procedure. Apoptosis was evaluated in sections from the whole fetal brain by TUNEL and caspase-3 staining. …


Is There Any Effect Of Demographic Features On Development Of Hyperemesis Gravidarum In The Turkish Population?, Zeynep Kamalak, Nermi̇n Köşüş, Aydin Köşüş, Deni̇z Hizli, Ayli̇n Ayrim, Gonca Kurt Jan 2013

Is There Any Effect Of Demographic Features On Development Of Hyperemesis Gravidarum In The Turkish Population?, Zeynep Kamalak, Nermi̇n Köşüş, Aydin Köşüş, Deni̇z Hizli, Ayli̇n Ayrim, Gonca Kurt

Turkish Journal of Medical Sciences

To assess the effect of maternal demographic variables on development of hyperemesis gravidarum (HG) in pregnant Turkish women. Materials and methods: Two hundred consecutive women with HG were defined as the study group, and 200 consecutive pregnant women without any signs or symptoms of HG matched for age, parity, and gestational age were defined as the control group. Personal information, including lifestyle, educational level, occupation, and economic status were obtained via questionnaire. Results: The number of abortions was higher but parity was lower in the HG group. The time interval between 2 pregnancies was significantly shorter in the HG group …


Association Between Maternal Ghrelin Levels And Hyperemesis Gravidarum, İkbal Kaygusuz, İlknur İnegöl Gümüş, Melahat Yildirim, Hüsametti̇n Erdamar, Aysel Uysal, Serap Aynur Si̇mavli, Abdullah Ayyildiz, Muhammet Ramazan Yi̇ği̇toğlu Jan 2013

Association Between Maternal Ghrelin Levels And Hyperemesis Gravidarum, İkbal Kaygusuz, İlknur İnegöl Gümüş, Melahat Yildirim, Hüsametti̇n Erdamar, Aysel Uysal, Serap Aynur Si̇mavli, Abdullah Ayyildiz, Muhammet Ramazan Yi̇ği̇toğlu

Turkish Journal of Medical Sciences

To investigate serum levels of ghrelin in pregnant women as a potential early marker for hyperemesis gravidarum (HG). Materials and methods: A cross-sectional study was carried out at Fatih University Hospital. Included in the study were 35 women with HG and 31 pregnant women without HG as a control group. The groups were compared in terms of age, gravidity, body mass index (BMI), and fasting serum thyroid-stimulating hormone (TSH) and ghrelin levels. Results: Ghrelin levels of the patients with HG were found to be significantly lower than those in the control group (P = 0.03). No intergroup differences could be …


Sigmoid Volvulus In Pregnancy, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk Jan 2012

Sigmoid Volvulus In Pregnancy, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk

Turkish Journal of Medical Sciences

To review the clinical outcomes of 9 patients with sigmoid volvulus (SV), a rare complication during pregnancy. Materials and methods: The clinical records of the patients were reviewed retrospectively. Results: The age range of the patients was 24-39 years (mean: 30.6 years). All patients were multiparous, and 6 patients (66.7%) were in the third trimester when diagnosed with SV. The main clinical features were abdominal pain/tenderness, obstipation, and distention in all patients (100.0%). The correct diagnosis was achieved based on clinical examination in 66.7% of the cases. Endoscopic detorsion was attempted in 6 patients (66.7%), with an 83.3% success rate. …


Maternal Smoking During Pregnancy And Effects On Neonatal Anthropometry: A Prospective Study, Fati̇h Bolat, Özge Eren, Güher Bolat, Emrah Can, Serdar Cömert, Hasan Si̇nan Uslu, Asi̇ye Nuhoğlu Jan 2012

Maternal Smoking During Pregnancy And Effects On Neonatal Anthropometry: A Prospective Study, Fati̇h Bolat, Özge Eren, Güher Bolat, Emrah Can, Serdar Cömert, Hasan Si̇nan Uslu, Asi̇ye Nuhoğlu

Turkish Journal of Medical Sciences

To identify risk factors associated with cigarette smoking during pregnancy and to evaluate the effect of smoking on anthropometric measurements. Materials and methods: This study was carried out prospectively in selected women who gave birth to a healthy, term infant at Şişli Etfal Education and Research Hospital from January 2009 to January 2010. Smoking status during pregnancy was categorized into 3 groups: nonsmoker; smoker; passive smoker. Regression analysis was performed to compare risk factors with cigarette smoking. Results: A total of 1175 mothers were enrolled. Active and passive smoking rates were 14.9% and 32.3%, respectively. In univariate analysis, maternal active …


Mean Platelet Volume As A Marker Of Future Cardiovascular Disease Risk In Pregnant Women With Impaired Fasting Glucose And Impaired Glucose Tolerance, Nermi̇n Köşüş, Aydin Köşüş, Ni̇lgün Turhan Jan 2012

Mean Platelet Volume As A Marker Of Future Cardiovascular Disease Risk In Pregnant Women With Impaired Fasting Glucose And Impaired Glucose Tolerance, Nermi̇n Köşüş, Aydin Köşüş, Ni̇lgün Turhan

Turkish Journal of Medical Sciences

To compare the mean platelet volume (MPV) of pregnant women with mild glycemic disorders with that of healthy pregnant women to find whether these disorders are risk factors for future cardiovascular disease. Materials and methods: Fasting blood glucose and 50-g oral glucose loading were measured. A 100-g, 3-h oral glucose tolerance test was done when plasma glucose was ≥140 mg/dL, following a loading test. According to the test results, 4 groups were formed: control, impaired fasting glucose, false positive loading test, and impaired glucose tolerance. The hematologic parameters were compared in all of the groups. Results: The mean MPV of …


Ileosigmoid Knotting In Pregnancy, Sabri̇ Selçuk Atamanalp Jan 2012

Ileosigmoid Knotting In Pregnancy, Sabri̇ Selçuk Atamanalp

Turkish Journal of Medical Sciences

Aim: Ileosigmoid knotting (ISK) is a rare event in pregnancy. This study reviewed the clinical outcomes of 3 pregnant patients with ISK and compared the characteristics of these pregnant women with 16 nonpregnant women. Materials and methods: The clinical records were reviewed retrospectively. Results: Three pregnant patients accounted for 4.2% of 72 total ISK patients and 15.8% of 19 female ISK patients. The ages of the patients were 35, 38, and 31 years (mean: 34.7 years). All of the patients were multiparous. Two patients (66.7%) were in the 3rd trimester and 1 (33.3%) was in the 2nd trimester. The mean …


Iodine Deficiency In Pregnancy And In Women Of Reproductive Age In Erzurum, Turkey, Kadi̇r Çeti̇nkaya, Meti̇n İngeç, Semra Çeti̇nkaya, İbrahi̇m Kaplan Jan 2012

Iodine Deficiency In Pregnancy And In Women Of Reproductive Age In Erzurum, Turkey, Kadi̇r Çeti̇nkaya, Meti̇n İngeç, Semra Çeti̇nkaya, İbrahi̇m Kaplan

Turkish Journal of Medical Sciences

Aim: Iodine deficiency (ID) is an important public health problem and the most common cause of preventable mental retardation. The aims of this study were to determine the urinary iodine concentration (UIC) of pregnant women living in Erzurum, to assess the ID rate, and to find out whether iodine supplementation is necessary in pregnancy. Materials and methods: Spot urine was obtained from pregnant and nonpregnant women with no functional or organic thyroid disease. The UIC was studied using the Sandell-Kolthoff method. Results: The median UIC values of pregnant women in the first, second, and third trimesters and of the nonpregnant …


Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh Jan 2012

Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh

Turkish Journal of Medical Sciences

Aim: To investigate the effect of prenatal exposure to cigarette smoke (CS) on the conduction of sensory nerve fibers in the adult rat offspring. Materials and methods: Pregnant rats were exposed to CS by inhalation during the gestation period. The saphenous nerve in the adult offspring was exposed in vivo, and the conduction parameters of the threshold, maximum strength of stimulation, conduction velocity, and amplitude of compound action potentials (CAPs) of A\alpha\beta-, A\delta-, and C-fibers were examined. Results: Prenatal exposure to CS induced significant reduction (P < 0.005) in the peak amplitude of CAPs of A\alpha\beta- and A\delta-fibers. The conduction velocity of A\alpha\beta-fibers and C-fibers was significantly (P < 0.025-0.05) increased after prenatal exposure to CS. Conclusion: Prenatal exposure to CS attenuates the conduction of sensory nerve fibers in the rat saphenous nerve.