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Articles 1621 - 1650 of 4871
Full-Text Articles in Medicine and Health Sciences
Conventional Versus Endoscopic Components Separation Technique: New Anthropometric Calculation For Selection Of Surgical Approach, Yaşar Subutay Peker, Oğuz Hançerli̇oğullari, Mehmet Fati̇h Can, Sezai̇ Demi̇rbaş
Conventional Versus Endoscopic Components Separation Technique: New Anthropometric Calculation For Selection Of Surgical Approach, Yaşar Subutay Peker, Oğuz Hançerli̇oğullari, Mehmet Fati̇h Can, Sezai̇ Demi̇rbaş
Turkish Journal of Medical Sciences
Background/aim: Giant ventral incisional hernias (GVIHs) are hard to manage for surgeons. This problem was resolved in 1990 with the components separation technique (CST). We aimed to compare endoscopic and conventional CST for GVIHs and find a new anthropometric calculation.Materials and methods: In this prospective nonrandomized clinical trial, 21 patients were treated with endoscopic or conventional CST between 2012 and 2016. Eight patients (38.1%) were operated endoscopically and 13 (61.9%) conventionally on the basis of preoperative tomography results, hernia surface area (HSA), number of recent abdominal operations, comorbidities, and the presence or history of ostomy. Groups in which prosthetic material …
Determination Of Liver Fibrosis Stages In Egyptian Chronic Hepatitis B Patients By A Noninvasive Tool, Waleed Serag, Magdy Mahmoud, Basem Eysa, Sara Mahmoud
Determination Of Liver Fibrosis Stages In Egyptian Chronic Hepatitis B Patients By A Noninvasive Tool, Waleed Serag, Magdy Mahmoud, Basem Eysa, Sara Mahmoud
Turkish Journal of Medical Sciences
Background/aim: Hepatitis B virus (HBV) infection is the leading cause of liver fibrosis (LF). The prognosis and management of patients with chronic hepatitis B virus depend on the amount and progression of liver fibrosis. Angiopoietin-like protein 2 (Angptl2) is not only a chronic inflammatory mediator, but also a tissue-remodeling factor. The aim of this study is to explore the predictive value of Angptl2 in different fibrosis stages in patients chronically infected with HBV. Materials and methods: Eighty patients with chronic HBV infection undergoing Fibroscan were included. Serum concentrations of Angptl2 were detected using a commercial ELISA kit.Results: Angptl2 levels were …
Bloodstream Infections In Pediatric Hematology/Oncology Patients: Six Years? Experience Of A Single Center In Turkey, Tuğçe Tural Kara, Tuğba Erat, Aysun Yahşi̇, Hali̇l Özdemi̇r, Di̇lber Tali̇a İleri̇, Eli̇f İnce, Nurdan Taçyildiz, Emel Ünal, Ergi̇n Çi̇ftci̇, Erdal İnce
Bloodstream Infections In Pediatric Hematology/Oncology Patients: Six Years? Experience Of A Single Center In Turkey, Tuğçe Tural Kara, Tuğba Erat, Aysun Yahşi̇, Hali̇l Özdemi̇r, Di̇lber Tali̇a İleri̇, Eli̇f İnce, Nurdan Taçyildiz, Emel Ünal, Ergi̇n Çi̇ftci̇, Erdal İnce
Turkish Journal of Medical Sciences
Background/aim: Bloodstream infections are the major cause of morbidity, increased cost, prolonged hospitalization, and mortality in pediatric patients. Identifying the predominant microorganisms and antimicrobial susceptibilities in centers helps to select effective empirical antimicrobials which leads to positive clinical outcomes. We aimed to identify the causative microorganisms and their antimicrobial susceptibilities in patients with bloodstream infections.Materials and methods: Data belonging to patients with hematological and/or oncological diseases admitted to our hospital with fever between January 2010 and November 2015 were analyzed. Results: In total, 71 patients who had 111 bloodstream infection episodes were included. Responsible pathogens were detected as follows: 35.1% …
Effect Of Parathyroidectomy On Epicardial Fat Thickness As A Cardiovascular Risk Factor In Patients With Primary Hyperparathyroidism, Muhammed Kizilgül, Mustafa Çalişkan, Selvi̇han Beysel, Mustafa Özbek, Erman Çakal
Effect Of Parathyroidectomy On Epicardial Fat Thickness As A Cardiovascular Risk Factor In Patients With Primary Hyperparathyroidism, Muhammed Kizilgül, Mustafa Çalişkan, Selvi̇han Beysel, Mustafa Özbek, Erman Çakal
Turkish Journal of Medical Sciences
Background/aim: Several studies demonstrated that primary hyperparathyroidism is related to increased risk for cardiovascular diseases (CVDs), and risk is decreased by parathyroidectomy. Epicardial fat thickness (EFT) has been postulated as a new marker of CVD risk. We evaluated the impact of parathyroidectomy on EFT in patients with primary hyperparathyroidism (PHPT).Materials and methods: Thirty-four PHPT patients (29 female, 5 male) and 28 age- and sex-matched controls (19 female, 9 male) were included in the study. Demographic, anthropometric, and biochemical data were recorded both before parathyroidectomy and 6 months after the procedure. Epicardial fat thickness was measured by transthoracic echocardiography.Results: Mean age …
Risk Factors For Bacteremia In Children With Febrile Neutropenia, Soner Sertan Kara, Hasan Tezer, Meltem Polat, Burcu Ceylan Cura Yayla, Tuğba Bedi̇r Demi̇rdağ, Arzu Okur, Ali̇ Fettah, Sali̇ha Kanik Yüksek, Anil Tapisiz, Zuhre Kaya, Namik Özbek, İdi̇l Yeni̇cesu, Hüsni̇ye Neşe Yarali, Ülker Koçak
Risk Factors For Bacteremia In Children With Febrile Neutropenia, Soner Sertan Kara, Hasan Tezer, Meltem Polat, Burcu Ceylan Cura Yayla, Tuğba Bedi̇r Demi̇rdağ, Arzu Okur, Ali̇ Fettah, Sali̇ha Kanik Yüksek, Anil Tapisiz, Zuhre Kaya, Namik Özbek, İdi̇l Yeni̇cesu, Hüsni̇ye Neşe Yarali, Ülker Koçak
Turkish Journal of Medical Sciences
Background/aim: Bacteremia remains an important cause of morbidity and mortality during febrile neutropenia (FN) episodes. We aimed to define the risk factors for bacteremia in febrile neutropenic children with hemato-oncological malignancies. Materials and methods: The records of 150 patients aged ?18 years who developed FN in hematology and oncology clinics were retrospectively evaluated. Patients with bacteremia were compared to patients with negative blood cultures.Results: The mean age of the patients was 7.5 ± 4.8 years. Leukemia was more prevalent than solid tumors (61.3% vs. 38.7%). Bacteremia was present in 23.3% of the patients. Coagulase-negative staphylococci were the most frequently isolated …
Validity And Reliability Of The Turkish Version Of The Cold Intolerance Symptom Severity Questionnaire, Nurten Gi̇zem Tore, Mesken Gümüşsoy, Deran Oskay
Validity And Reliability Of The Turkish Version Of The Cold Intolerance Symptom Severity Questionnaire, Nurten Gi̇zem Tore, Mesken Gümüşsoy, Deran Oskay
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine validity and reliability of the Turkish version of the Cold Intolerance Symptom Severity (CISS-T) Questionnaire. Materials and methods: The translation and back translation steps of the study were based on the Beaton guidelines. Sixty-eight patients between 18 and 65 years old with cold intolerance after amputation, replantation, multiple crush syndrome, and peripheral nerve injury were included in the study. Patients completed the Disabilities of the Arm, Shoulder, and Hand Questionnaire (DASH), the SF-36 Quality of Life Questionnaire, and the single questions assessing the cold sensitivity and cold intolerance once and the …
Elevated Neutrophil To Lymphocyte Ratio As An Indicator Of Secondary Erythema Nodosum, A Retrospective Observational Study, Yildiz Hayran, Ayşe Öktem, Emi̇ne Buket Şahi̇n, Pinar İncel Uysal, Nuran Alli, Başak Yalçin
Elevated Neutrophil To Lymphocyte Ratio As An Indicator Of Secondary Erythema Nodosum, A Retrospective Observational Study, Yildiz Hayran, Ayşe Öktem, Emi̇ne Buket Şahi̇n, Pinar İncel Uysal, Nuran Alli, Başak Yalçin
Turkish Journal of Medical Sciences
Background/aim: Erythema nodosum (EN) is an inflammatory disorder of subcutaneous tissue. Although etiopathogenesis of the disease is unknown, many predisposing factors such as infections, systemic disease, and drugs have been identified. Neutrophil to lymphocyte ratio (NLR) has been shown to be a novel inflammatory marker in many dermatological diseases. The aim of our study is to investigate NLR in EN patients and evaluate its relation to the underlying cause of the disease.Materials and methods: Between 2014 and 2018, clinical and laboratory data of 395 patients diagnosed with EN and 395 controls were extracted from patient files. EN patients were grouped …
In Vitro Combination Of Tigecycline With Other Antibiotics In Stenotrophomonas Maltophilia Isolates, Di̇lek Karamanlioğlu, Murat Di̇zbay
In Vitro Combination Of Tigecycline With Other Antibiotics In Stenotrophomonas Maltophilia Isolates, Di̇lek Karamanlioğlu, Murat Di̇zbay
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the usefulness of tigecycline in combination treatment of Stenotrophomonas maltophilia infections by evaluating the in vitro synergistic effects of tigecycline with various antibiotics using the E-test method.Materials and methods: Synergy testing by E-test was performed with various antibiotic combinations in 10 S. maltophilia isolates identified as a cause of infection. The antibiotics used in the study included tigecycline (TGC), cefoperazone-sulbactam (CPS), ceftazidime (TZ), levofloxacin (LEV), and trimethoprim-sulfamethoxazole (cotrimoxazole)(TS). Four different combinations (TGC-CPS, TGC-TZ, TGC-LEV, TGC-TS) were studied with the E-test synergy method. Results: S. maltophilia isolates were found to have the …
Effects Of Different Percentages Of Body Weight-Supported Treadmill Training In Parkinson's Disease: A Double-Blind Randomized Controlled Trial, Tuğba Atan, Özden Özyemi̇şci̇ Taşkiran, Ayşe Bora Tokçaer, Gülçi̇n Kaymak Karataş, Asli Karakuş Çalişkan, Belgi̇n Karaoğlan
Effects Of Different Percentages Of Body Weight-Supported Treadmill Training In Parkinson's Disease: A Double-Blind Randomized Controlled Trial, Tuğba Atan, Özden Özyemi̇şci̇ Taşkiran, Ayşe Bora Tokçaer, Gülçi̇n Kaymak Karataş, Asli Karakuş Çalişkan, Belgi̇n Karaoğlan
Turkish Journal of Medical Sciences
Background/aim: Body weight-supported treadmill training (BWSTT) might have greater effects than conventional treadmill training (TT) in neurological diseases such as Parkinson's disease (PD). The aim of this study was to evaluate the effects of different percentages of BWSTT on gait, balance, quality of life, and fatigue in PD.Materials and methods: Thirty-five patients with moderate to advanced PD were randomized into three BWSTT groups according to the supported percentage of body weight: 0% BWSTT (control group; unsupported TT), 10% BWSTT, or 20% BWSTT. Five patients were excluded due to early discharge and 30 patients completed BWSTT sessions lasting 30 min, 5 …
Evaluation Of The Correlation Between Quantitative Measurement Of The Foveal Avascular Zone And Retinal Vessel Density And Outer Retinal Disruptions In Diabetic Patients, Nagi̇han Uğurlu, Ayşe Güzi̇n Taşlipinar Uzel, Ahmet Şengün, Fatma Yülek, Demet Özdaş, Abbas Ali̇ Tam, Reyhan Ersoy, Beki̇r Çakir
Evaluation Of The Correlation Between Quantitative Measurement Of The Foveal Avascular Zone And Retinal Vessel Density And Outer Retinal Disruptions In Diabetic Patients, Nagi̇han Uğurlu, Ayşe Güzi̇n Taşlipinar Uzel, Ahmet Şengün, Fatma Yülek, Demet Özdaş, Abbas Ali̇ Tam, Reyhan Ersoy, Beki̇r Çakir
Turkish Journal of Medical Sciences
Background/aim: The aim of the current study was to evaluate the correlation between the integrity of the outer retinal layers on optical coherence tomography (OCT) and objective parameters of retinal microvascular perfusion on optical coherence tomography angiography (OCTA).Materials and methods: A total of 105 eyes of 54 diabetic patients were included in the study. Integrity of the outer retinal layers including the external limiting membrane (ELM), ellipsoid zone (EZ), and interdigitation zone (IZ) was assessed by spectral-domain optical coherence tomography. The foveal avascular zone (FAZ) area and vessel density (VD) measurements in the superficial capillary plexus (SCP) and deep capillary …
The Effect Of Technical Details Of Percutaneous Catheter Drainage On The Clinical Outcomes Of Infected Necrotizing Pancreatitis Patients, Zhi-Hua Zhang, Yi-Xuan Ding, Yu-Duo Wu, Chong-Chong Gao, Fei Li
The Effect Of Technical Details Of Percutaneous Catheter Drainage On The Clinical Outcomes Of Infected Necrotizing Pancreatitis Patients, Zhi-Hua Zhang, Yi-Xuan Ding, Yu-Duo Wu, Chong-Chong Gao, Fei Li
Turkish Journal of Medical Sciences
Background/aim: This study aimed to investigate the effect of technical details of percutaneous catheter drainage (PCD) on the clinical outcomes of patients with infected necrotizing pancreatitis (INP).Materials and methods: A total of 44 INP patients treated in our hospital from October 2013 to October 2015 were included. The correlations of the first PCD treatment data and the clinical outcomes were analyzed.Results: The number of catheters was positively correlated with hospital readmission (r = 0.335, P = 0.032). Receiver operating characteristic curve analysis showed that patients with ? 3 catheters were more likely to have hospital readmission. Patients with pleural effusion …
Kinesiophobia And Related Factors In Systemic Lupus Erythematosus Patients, Songül Bağlan Yentür, Sali̇ha Karatay, Deran Oskay, Abdurrahman Tufan, Hami̇t Küçük, Şemi̇nur Haznedaroğlu
Kinesiophobia And Related Factors In Systemic Lupus Erythematosus Patients, Songül Bağlan Yentür, Sali̇ha Karatay, Deran Oskay, Abdurrahman Tufan, Hami̇t Küçük, Şemi̇nur Haznedaroğlu
Turkish Journal of Medical Sciences
Background/aim: This study was designed to investigate the relationship between kinesiophobia and the level of physical activity, depression, disease activity, fatigue, pain, and quality of life in female patients with systemic lupus erythematosus (SLE).Materials and methods: Seventy volunteer female patients were included in the study. Kinesiophobia, physical activity level, disease activity, fatigue, depression, pain, and quality of life were assessed using the Tampa Scale for Kinesiophobia (TSK), International Physical Activity Questionnaire- Short Form (IPAQ), Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), Fatigue Severity Scale (FSS), Beck Depression Inventory (BDI), McGill Pain Questionnaire- Short Form (MPQ-SF) and Nottingham Health Profile (NHP), …
Does Different Subfertility Etiology Affect Pregnancy Rates In Intrauterineinsemination Cycles?, Batuhan Turgay, Yavuz Emre Şükür, Batuhan Özmen, Ruhşen Aytaç, Cem Somer Atabekoğlu, Bülent Berker, Murat Sönmezer
Does Different Subfertility Etiology Affect Pregnancy Rates In Intrauterineinsemination Cycles?, Batuhan Turgay, Yavuz Emre Şükür, Batuhan Özmen, Ruhşen Aytaç, Cem Somer Atabekoğlu, Bülent Berker, Murat Sönmezer
Turkish Journal of Medical Sciences
Background/aim: To investigate the relationship between subfertility etiologies and success rates in controlled ovarian stimulation and intrauterine insemination (COS?IUI) cycles.Materials and methods: The medical records of 218 couples who applied to a university-based fertility center were analyzed retrospectively. Detailed infertility examination data and pregnancy outcomes were compared according to different subfertility etiologies. The study groups with regard to subfertility etiologies were minimal?mild endometriosis, unexplained infertility, and mild male infertility. The primary outcome measure was live birth rate.Results: There were no statistically significant differences between the groups regarding demographics except for total motile sperm count. Live birth rates in the male …
Protective Effect Of Cyclosporine A In The Treatment Of Severe Hydronephrosis In A Rabbit Renal Pelvic Perfusion Model, Ben Zheng Zhou, Da Hu Zhang, Wei Min Yu, Jin Zhuo Ning
Protective Effect Of Cyclosporine A In The Treatment Of Severe Hydronephrosis In A Rabbit Renal Pelvic Perfusion Model, Ben Zheng Zhou, Da Hu Zhang, Wei Min Yu, Jin Zhuo Ning
Turkish Journal of Medical Sciences
Background/aim: Cyclosporine A (CsA), a traditional immunosuppressive compound, has been reported to specifically prevent isch-emia reperfusion tissue injury via apoptosis pathway. This study aimed to explore the renoprotective effects of CsA on the kidneys of rabbits undergoing renal pelvic perfusion.Materials and methods: A total of 30 rabbits were randomly assigned into a control group (n = 6) and an experimental group (n = 24). The experimental group underwent a surgical procedure that induced severe hydronephrosis and was then stochastically divided into 4 groups (S1, S1?, S2, and S2?), consisting of 6 rabbits each. Groups S1 and S1? were perfused with …
Neuroprotective Role Of Delta Opioid Receptors In Hypoxic Preconditioning, Şevi̇n Güney, Si̇bel Di̇ncer, Güleser Göktaş, Gülnur Take Kaplanoğlu
Neuroprotective Role Of Delta Opioid Receptors In Hypoxic Preconditioning, Şevi̇n Güney, Si̇bel Di̇ncer, Güleser Göktaş, Gülnur Take Kaplanoğlu
Turkish Journal of Medical Sciences
Background/aim: The purpose of the present study was to explore the neuroprotective role of delta opioid receptors (DOR) in the rat cortex in hypoxic preconditioning. Materials and methods: Rats were randomly divided into 8 groups: control (C), sham (S), hypoxic preconditioning (PC), severe hypoxia (SH), PC + SH, PC + SH + Saline (PS), PC + SH + DPDPE (DPDPE, selective DOR agonist), PC + SH + NT (NT, Naltrindole, selective DOR antagonist). Drugs were administered intracerebroventrically. Twenty four h after the end of 3 consecutive days of PC (10% O2, 2 h/day), the rats were subjected to severe hypoxia …
Seasonal, Sex Variations In Vitamin D Levels And Their Association With Pulmonary Function In Children With Asthma, Şebnem Özdoğan
Seasonal, Sex Variations In Vitamin D Levels And Their Association With Pulmonary Function In Children With Asthma, Şebnem Özdoğan
Turkish Journal of Medical Sciences
Background/aim: We aimed to examine the seasonal and sex variations in vitamin D levels in children with asthma and their associations with lung function. Materials and methods: We conducted a cohort study involving children aged 7?17 years old with asthma. Vitamin D levels were obtained and pulmonary function tests (PFTs) were performed in winter months (December, January, and February) and at the end of summer (August, September, and October). Seasonal and sex variations in vitamin D levels and lung function were examined. Results: A total of 56 children (26 males, mean age: 11.93 ± 1.8) were enrolled. The mean vitamin …
A Novel Marker Relationship Between Carotid Intima-Media Thickness And Disease Activity Score-28 In Patients With Rheumatoid Arthritis: Human Endothelial Cell-Specific Molecule-1, Göksel Tuzcu, Ali̇ Uğur Uslu, Ayça Tuzcu, Rabi̇a Aydoğan Baykara, Ahmet Omma, Adem Küçük
A Novel Marker Relationship Between Carotid Intima-Media Thickness And Disease Activity Score-28 In Patients With Rheumatoid Arthritis: Human Endothelial Cell-Specific Molecule-1, Göksel Tuzcu, Ali̇ Uğur Uslu, Ayça Tuzcu, Rabi̇a Aydoğan Baykara, Ahmet Omma, Adem Küçük
Turkish Journal of Medical Sciences
Background/aim: Human endothelial cell-specific molecule-1 (endocan) is a marker of vascular endothelial dysfunction that may be used in the evaluation of inflammatory-associated atherosclerotic lesions. Endocan may be a marker for the evaluation of atherosclerosis and disease activity in rheumatoid arthritis (RA) patients.Materials and methods: We included 39 RA patients assessed according to the American College of Rheumatology/European League Against Rheumatology 2010 diagnostic criteria and recruited 30 age- and sex-matching healthy subjects for the control group.Results: Endocan values were 14.11 ± 3.27 for the RA patients and 12.10 ± 2.92 for the controls. The endocan values of the patients were significantly …
The Role Of Right Ventricular Volumes And Inferior Vena Cava Diameters In The Evaluation Of Volume Status Before Colonoscopy, Şule Arican, Ramazan Dertli̇, Çağdaş Dağli, Gülçi̇n Hacibeyoğlu, Mustafa Koyuncu, Ahmet Topal, Sema Tuncer Uzun, Mehmet Asil
The Role Of Right Ventricular Volumes And Inferior Vena Cava Diameters In The Evaluation Of Volume Status Before Colonoscopy, Şule Arican, Ramazan Dertli̇, Çağdaş Dağli, Gülçi̇n Hacibeyoğlu, Mustafa Koyuncu, Ahmet Topal, Sema Tuncer Uzun, Mehmet Asil
Turkish Journal of Medical Sciences
Background/aim: Ultrasonographic measurements of inferior vena cava (IVC) diameters and right ventricle (RV) volumes are important tools for the evaluation of intravascular volume. The current study investigates the association of IVC diameters and RV volumes before colonoscopy in prediction of postanesthesia hypotension.Materials and methods: Seventy patients scheduled for colonoscopy were included in the study. Preoperatively, expirium (dIVC max) and inspirium (dIVC min) IVC diameters were measured using M-mode ultrasonography and the collapsibility index (IVC-CI) was calculated. Ventricular volumes and areas were also measured using transthoracic echocardiography. Postanesthesia hypotension was defined as mean arterial blood pressure of 30% in the mean …
Initial Regional Evaluation Of The Cystic Fibrosis Newborn Screening Program: Data From The Mediterranean Coast Of Turkey, Abdurrahman Erdem Başaran, Ayşen Başaran, Di̇lara Fatma Kocacik, Özgül Alper, Deni̇z Acican, Ayşen Bi̇ngöl
Initial Regional Evaluation Of The Cystic Fibrosis Newborn Screening Program: Data From The Mediterranean Coast Of Turkey, Abdurrahman Erdem Başaran, Ayşen Başaran, Di̇lara Fatma Kocacik, Özgül Alper, Deni̇z Acican, Ayşen Bi̇ngöl
Turkish Journal of Medical Sciences
Background/ aim: Since January 2015, the Cystic Fibrosis Newborn Screening (CFNS) program has been implemented in Turkey. We aimed to evaluate the demographic, clinical, and laboratory data of cases referred from the CFNS program and to determine the most suitable cut-off value for immunoreactive trypsinogen (IRT)-1 and immunoreactive trypsinogen (IRT-2) that are used in the CFNS program in Turkey. Materials and methods: A total of 156 Turkish Caucasian subjects were determined as positive cases during 3 years, from January 2015 to January 2018, and were referred to the pediatric pulmonology clinics of Akdeniz University Hospital, Antalya, Turkey, for the national …
The Validity And Reliability Of The Turkish Version Of The Physical Activity Scale For Individuals With Physical Disabilities (Pasipd), Kardem Ulaş, Semra Topuz, Gönül Horasan
The Validity And Reliability Of The Turkish Version Of The Physical Activity Scale For Individuals With Physical Disabilities (Pasipd), Kardem Ulaş, Semra Topuz, Gönül Horasan
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to assess the validity and reliability of Turkish translation of thePhysical Activity Scale for Individuals with Physical Disabilities (PASIPD) in a disabled Turkish population.Materials and methods: Following the translation protocol of the PASIPD, the Turkish version of the PASIPD, Short Form-36, and International Physical Activity Questionnaire were administered to 198 developmentally and physically disabled individuals.Results: The Turkish version of the PASIPD was found to be reliable. The domains of the Turkish version of the PASIPD were also found to be valid. Four factors were obtained from the questionnaire. The ICC was 1.0 since …
The Effect Of Parathyroidectomy On Bone Mineral Density In Primary Hyperparathyroidism, Mustafa Çalişkan, Selvi̇han Beysel, Muhammed Kizilgül, Mustafa Özbek, Erman Çakal
The Effect Of Parathyroidectomy On Bone Mineral Density In Primary Hyperparathyroidism, Mustafa Çalişkan, Selvi̇han Beysel, Muhammed Kizilgül, Mustafa Özbek, Erman Çakal
Turkish Journal of Medical Sciences
Background/aim: This study aimed to investigate the change in bone mineral density (BMD) before and 1 year after parathyroidectomy in patients with primary hyperparathyroidism (PHPT). Materials and methods: The clinical and biochemical parameters and DEXA screening of patients with symptomatic PHPT (n = 28) and asymptomatic PHPT (n = 63) were investigated before and 1 year after parathyroidectomy. Results: Patients with symptomatic PHPT had a higher prevalence of nephrolithiasis (18.2% vs. 4.6%, P = 0.032) when compared to the prevalence in patients with asymptomatic PHPT. The prevalence of osteoporosis in the lumbar spine (63.0% vs. 37.5%, P = 0.026) and …
Clinical Results Of Intradiscal Hydrogel Administration (Gelstix) In Lumbar Degenerative Disc Disease, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken
Clinical Results Of Intradiscal Hydrogel Administration (Gelstix) In Lumbar Degenerative Disc Disease, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken
Turkish Journal of Medical Sciences
Background/aim: Degenerative disc disease (DDD) is one of the main causes of lower back pain. In this study, we evaluate the efficacy of percutaneous intradiscal GelStix administration in patients with discogenic pain due to lumbar DDD who were unresponsive to conservative methods.Materials and methods: A total of 29 patients were included in the study, which took place between 2013 and 2017. Sedation was performed in the prone position in the operating room, and a C-arm was located so as to provide a lateral view of the surgical field. A 22-G, 3.5-inch needle was inserted into the center of the disc …
Pipeline Flex Embolization Device (Ped Flex) For The Treatment Of Intracranial Aneurysms: Periprocedural Outcomes And First-Year Angiographic Results, Şükrü Oğuz, Ömer Naci̇ Tabakci, Ender Uysal, Eser Bulut, Hasan Di̇nç
Pipeline Flex Embolization Device (Ped Flex) For The Treatment Of Intracranial Aneurysms: Periprocedural Outcomes And First-Year Angiographic Results, Şükrü Oğuz, Ömer Naci̇ Tabakci, Ender Uysal, Eser Bulut, Hasan Di̇nç
Turkish Journal of Medical Sciences
Background/aim: The Pipeline Flex Embolization Device (PED Flex) is a new updated version of the PED classic that incorporates a new delivery system to allow facilitation of stent deployment, resheathing, and removal of the capture coil. This study evaluated the PED Flex in terms of the technical aspects of the procedure and first-year follow-up results. Materials and methods: This retrospective study involved prospectively collected data from May 2015 to August 2017. The primary endpoint was technical aspects of the procedure, and the secondary endpoint was first-year follow-up results. Results: Forty-nine patients with 59 target intracranial aneurysms were enrolled. Patients' mean …
The Effect Of Pregabalin On Tourniquet-Induced Ischemia-Reperfusion Injury:A Prospective Randomized Study, Ömer Karaca, Hüseyi̇n Ulaş Pinar, Ahmet Fevzi̇ Özgür, Sevsen Kulaksizoğlu, Rafi̇ Doğan
The Effect Of Pregabalin On Tourniquet-Induced Ischemia-Reperfusion Injury:A Prospective Randomized Study, Ömer Karaca, Hüseyi̇n Ulaş Pinar, Ahmet Fevzi̇ Özgür, Sevsen Kulaksizoğlu, Rafi̇ Doğan
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the efficacy of pregabalin on ischemia-reperfusion injuries.Materials and methods: Fifty-four patients were randomly assigned into 2 groups. A 150-mg tablet of pregabalin was given the night before and then 1 h before the operation for patients in Group P (pregabalin group, n = 27). A placebo was given to patients in Group C (control group, n = 27) at the same times. After combined spinal-epidural anesthesia was performed, venous blood samples were taken before tourniquet inflation (t1), just before tourniquet deflation (t2), and 20 min after tourniquet deflation (t3) for the …
Abdominal Girth Has A Strong Correlation With Actual And Ultrasound Estimated Epidural Depth, Mehmet Cantürk, Nazan Kocaoğlu, Meltem Hakki
Abdominal Girth Has A Strong Correlation With Actual And Ultrasound Estimated Epidural Depth, Mehmet Cantürk, Nazan Kocaoğlu, Meltem Hakki
Turkish Journal of Medical Sciences
Background/aim: This study aimed to assess the correlations of actual epidural depth (ND) and ultrasound estimated epidural depth in the paramedian sagittal oblique plane (ED/PSO) and transverse median plane (ED/TM) with the abdominal girth (AG), body mass index (BMI), and weight of patients. Materials and methods: One hundred and thirty patients of either sex scheduled for unilateral inguinal hernia repair were enrolled. ED/PSO and ED/TM were assessed with a 2-5 MHz curved array probe at the L3-4 intervertebral space. The epidural needle was marked with a sterile marker upon locating the epidural space. The ND was assessed by measuring the …
Assessment Of The Visual Pathways In Patients With Neurofibromatosis-1 By 3s-Space Technique With 3-Tesla Mri, Özge Saraç, Oktay Algin, Mehmet Beyazal, Fatma Banu Anlar, Ali̇ Varan, Adi̇le Tülay Kansu
Assessment Of The Visual Pathways In Patients With Neurofibromatosis-1 By 3s-Space Technique With 3-Tesla Mri, Özge Saraç, Oktay Algin, Mehmet Beyazal, Fatma Banu Anlar, Ali̇ Varan, Adi̇le Tülay Kansu
Turkish Journal of Medical Sciences
Background/aim: We aimed to evaluate the size/tortuosity of the optic nerve (ON) and the dilatation of the ON sheath (ONS) in neurofibromatosis type 1 (NF-1) patients with 3T-MRI, and to assess the usefulness of 3D-SPACE in imaging the optic pathway, ON, and ONS in NF-1 patients. Materials and methods: Twenty consecutive NF-1 patients without optic pathway glioma (OPG) (Group 1), 16 consecutive NF-1 patients with OPG (Group 2), and 19 controls were included in this study. The thickness and tortuosity of the ON and the diameter of the ONS were measured on STIR and 3D-SPACE images. Results: The thickness of …
Can We Predict Patients That Will Not Benefit From Invasive Mechanical Ventilation? A Novel Scoring System In Intensive Care: The Imv Mortality Prediction Score (Impres), Tevfi̇k Özlü, Mehtap Pehli̇vanlar Küçük, Akin Kaya, Esra Yarar, Sami̇ Cenk Kirakli, Özlem Şengören Di̇ki̇ş, Hale Kefeli̇ Çeli̇k, Serdar Özkan, Hayri̇ye Bektaş Aksoy, Ahmet Oğuzhan Küçük
Can We Predict Patients That Will Not Benefit From Invasive Mechanical Ventilation? A Novel Scoring System In Intensive Care: The Imv Mortality Prediction Score (Impres), Tevfi̇k Özlü, Mehtap Pehli̇vanlar Küçük, Akin Kaya, Esra Yarar, Sami̇ Cenk Kirakli, Özlem Şengören Di̇ki̇ş, Hale Kefeli̇ Çeli̇k, Serdar Özkan, Hayri̇ye Bektaş Aksoy, Ahmet Oğuzhan Küçük
Turkish Journal of Medical Sciences
Background/aim: The present study aimed to define the clinical and laboratory criteria for predicting patients that will not benefit from invasive mechanical ventilation (IMV) treatment and determine the prediction of mortality and prognosis of these critical ill patients. Materials and methods: The study was designed as an observational, multicenter, prospective, and cross-sectional clinical study. It was conducted by 75 researchers at 41 centers in intensive care units (ICUs) located in various geographical areas of Turkey. It included a total of 1463 ICU patients who were receiving invasive mechanical ventilation (IMV) treatment. A total of 158 parameters were examined via logistic …
Neutrophil-To-Lymphocyte Ratio, Monocyte-To-Lymphocyte Ratio, And Platelet-To-Lymphocyte Ratio In Different Etiological Causes Of Thyrotoxicosis, Işilay Taşkaldiran, Tülay Omma, Çağatay Emi̇r Önder, Sevde Nur Firat, Gönül Koç, Mustafa Kemal Kiliç, Şeri̇fe Mehli̇ka Kuşkonmaz, Cavi̇t Çulha
Neutrophil-To-Lymphocyte Ratio, Monocyte-To-Lymphocyte Ratio, And Platelet-To-Lymphocyte Ratio In Different Etiological Causes Of Thyrotoxicosis, Işilay Taşkaldiran, Tülay Omma, Çağatay Emi̇r Önder, Sevde Nur Firat, Gönül Koç, Mustafa Kemal Kiliç, Şeri̇fe Mehli̇ka Kuşkonmaz, Cavi̇t Çulha
Turkish Journal of Medical Sciences
Background/aim: The most common causes of thyrotoxicosis include Graves' disease (GD), toxic multinodular goiter (TMNG), toxic adenoma (TA), and subacute granulomatous thyroiditis (SAT). In our study, we aimed to see whether neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) may be helpful in the differential diagnosis of these diseases.Materials and methods: We retrospectively analyzed the hospital records of the Endocrinology Clinic of our hospital between 2016 and 2019. We included data from 66 GD, 37 TA, and 35 SAT patients. We compared the data with those of 35 healthy subjects as controls.Results: NLR, MLR, …
Development And Psychometric Testing Of The Family Functioning Questionnaire In Rehabilitation (Ffqr), Hati̇ce Abaoğlu, Esra Aki
Development And Psychometric Testing Of The Family Functioning Questionnaire In Rehabilitation (Ffqr), Hati̇ce Abaoğlu, Esra Aki
Turkish Journal of Medical Sciences
Background/aim: The present study aimed to develop a reliable and valid assessment tool for measuring family functioning in rehabilitation. Materials and methods: Semistructured interviews were performed with 100 rehabilitation professionals working in pediatrics to identify the feature to be measured. The items determined with the qualitative analysis of the data were presented to 14 experts and content validity was provided. The questionnaire created based on the judgments of the experts was administered to 440 parents of children with special needs. Results: After validity and reliability analysis, the final version of the questionnaire comprised 48 items with four factors identified as …
The Effect Of N-Acetylcysteine On Inflammation And Oxidative Stress In Cisplatin-Induced Nephrotoxicity: A Rat Model, İnayet Güntürk, Cevat Yazici, Sema Kader Köse, Fatma Dağli, Bi̇lal Yücel, Arzu Hanim Yay
The Effect Of N-Acetylcysteine On Inflammation And Oxidative Stress In Cisplatin-Induced Nephrotoxicity: A Rat Model, İnayet Güntürk, Cevat Yazici, Sema Kader Köse, Fatma Dağli, Bi̇lal Yücel, Arzu Hanim Yay
Turkish Journal of Medical Sciences
Background/Aim: Cisplatin is a highly effective chemotherapeutic agent used in the treatment of solid organ cancers. Besides its chemotherapeutic effectiveness, cisplatin administration is associated with numerous side effects. Of those, the most clinically significant and common effect is nephrotoxicity. Recent studies reported that oxidative stress and inflammation are probably the most important mechanisms that contribute to the nephrotoxicity. N-acetylcysteine (NAC) is an antioxidant and antiinflammatory agent. In the present study, the effects of NAC on cisplatin-induced nephrotoxicity were investigated. Materials and methods: Rats were divided into four groups each including eight rats: CONT, NAC-250, CP, and CP+NAC. Rats in experimental …