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Articles 1591 - 1620 of 4871
Full-Text Articles in Medicine and Health Sciences
Does Transrectal Ultrasonography-Guided Biopsy Of The Prostate Lead To Possible Further Metastasis Via Circulating Tumor Cells?, Mustafa Kemal Ati̇lla, Bahatti̇n Avci, Lokman İrkilata, Mustafa Aydin, Alper Bi̇tki̇n, Mevlüt Keleş, İnci̇ Yücel, Mahmut Ulubay
Does Transrectal Ultrasonography-Guided Biopsy Of The Prostate Lead To Possible Further Metastasis Via Circulating Tumor Cells?, Mustafa Kemal Ati̇lla, Bahatti̇n Avci, Lokman İrkilata, Mustafa Aydin, Alper Bi̇tki̇n, Mevlüt Keleş, İnci̇ Yücel, Mahmut Ulubay
Turkish Journal of Medical Sciences
Background/aim: We evaluate whether transrectal ultrasonography (TRUS)-guided prostate biopsy might lead to spillage of tumor cells into peripheral blood as a result of disruption of the epithelial barrier and ultimately result in metastasis. Materials and methods: Eighty-eight patients underwent TRUS-guided prostate needle biopsy due to prostate-specific antigen (PSA) increase or abnormal digital rectal examination at the Samsun Research and Training Hospital (Samsun, Turkey) between April 2016 and September 2018. Approximately 10 mL of whole blood was collected from patients before, 1 week after, and 1 month after biopsy. Samples were analyzed for CD117 positivity and prostate-specific membrane antigen (PSMA) levels …
Cross-Cultural Adaptation, Reliability, And Validity Of The Turkish Version Of The Neck Outcome Score, Şeyda Candeni̇z, Seyi̇t Çitaker, Batuhan Bakirarar
Cross-Cultural Adaptation, Reliability, And Validity Of The Turkish Version Of The Neck Outcome Score, Şeyda Candeni̇z, Seyi̇t Çitaker, Batuhan Bakirarar
Turkish Journal of Medical Sciences
Background/aim: This study aims to determine the validity and reliability of the Turkish version of the Neck OutcOme Score (NOOS).Materials and methods: Two hundred eight patients suffering from nonspecific neck pain participated in the study. Test-retest reliability and internal consistency were assessed using intraclass correlation coefficients (2, 1) and Cronbach's alpha, respectively. The dimensionality was investigated with the factor analysis. The construct validity was determined by testing whether the hypothesis of correlations between NOOS subscales, Short Form-36 subscales, and the Neck Disability Index were met using Spearman's rank correlation coefficient. Ceiling/floor effects and measurement error were tested as well.Results: The …
Is The Asymmetry Between The Vertebral Arteries Related To Cerebral Dominance?, Ahmet Vural, Esma Esi̇n Deri̇n Çi̇çek
Is The Asymmetry Between The Vertebral Arteries Related To Cerebral Dominance?, Ahmet Vural, Esma Esi̇n Deri̇n Çi̇çek
Turkish Journal of Medical Sciences
Background/aim: The two vertebral arteries (VAs) are usually unequal in size; the left one is generally larger than the right one. It was hypothesized that the asymmetry results from the need of the dominant cerebral hemisphere for more glucose and oxygen, i.e. more blood supply. In this study, we aimed to test this hypothesis in patients by evaluating their arterial diameter and hand preference, as it is the most common criterion to determine the dominance of the hemisphere. Materials and methods: The study was performed with 844 participants who consented to participate in the study. We identified the dominant cerebral …
Retrospective Evaluation Of Anesthetic Techniques In Pregnant Women With Renal Transplantation, Asuman Sargin, Semra Karaman, Şeyda Ceylan Ari, Ali̇ Akdemi̇r, İsmet Hortu
Retrospective Evaluation Of Anesthetic Techniques In Pregnant Women With Renal Transplantation, Asuman Sargin, Semra Karaman, Şeyda Ceylan Ari, Ali̇ Akdemi̇r, İsmet Hortu
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate anesthesia management in cesarean operation of pregnant women who underwent renal transplantation and the effects on postoperative renal function, retrospectively.Materials and methods: After obtaining the approval of the ethics committee of our hospital, the records of pregnant women who underwent kidney transplantation and cesarean section between 2007 and 2017 were retrospectively analyzed. The patients' demographic data, concomitant disease history, the treatment received, and type of anesthesia were retrospectively evaluated and recorded in the follow-up form.Results: It was found that a total of 47 women who underwent renal transplantation had 47 live …
Rasch Analysis Of The Neck Bournemouth Questionnaire: Turkish Version, Validity, And Reliability Study, Yasemi̇n Özel Asliyüce, Derya Gökmen, Özlem Ülger
Rasch Analysis Of The Neck Bournemouth Questionnaire: Turkish Version, Validity, And Reliability Study, Yasemi̇n Özel Asliyüce, Derya Gökmen, Özlem Ülger
Turkish Journal of Medical Sciences
Background/aim: The multidimensional evaluation of patients with chronic neck pain is important for planning the treatment program. The aim of this study was to investigate the validity and reliability of the Turkish version of the Neck Bournemouth Questionnaire (NBQ).Materials and methods: The internal construct validity of the NBQ was examined by the fit of the data to the Rasch measurement model. External validity of the NBQ was evaluated by testing for expected associations of Rasch transformed NBQ score with the corresponding variables through the process of convergent validity. The reliability of the NBQ in terms of both internal consistency and …
Validity And Reliability Study Of The Turkish Version Of The Postoperative Recovery Index Of Patients Undergoing Surgical Intervention, Hande Cengi̇z, Di̇lek Aygi̇n
Validity And Reliability Study Of The Turkish Version Of The Postoperative Recovery Index Of Patients Undergoing Surgical Intervention, Hande Cengi̇z, Di̇lek Aygi̇n
Turkish Journal of Medical Sciences
Background/aim: For the purpose of providing the optimal postoperative care for patients and assisting them in terms of recovery, their health conditions and particular symptoms should be evaluated systematically with an appropriate measurement tool. This research was designed with the purpose of conducting the validity and reliability study of the Postoperative Recovery Index-Turkish Version (PoRI-TR) and determining the postoperative recovery conditions.Materials and methods: The sample of this study, which was planned methodologically and analytically, consisted of 382 patients who had a surgical intervention in a university hospital between September 2016 and June 2017. Analyses concerning the Turkish validity and reliability …
Investigation Of The Relationship Between Ischemic Stroke And Endothelial Nitric Oxide Synthase Gene Polymorphisms [G894t, Intron 4 Vntr And T786c], Süleyman Ömer Anliaçik, Osman Serhat Tokgöz, Ayşegül Zamani̇, Mahmut Selman Yildirim, Mehmet Si̇nan İyi̇soy
Investigation Of The Relationship Between Ischemic Stroke And Endothelial Nitric Oxide Synthase Gene Polymorphisms [G894t, Intron 4 Vntr And T786c], Süleyman Ömer Anliaçik, Osman Serhat Tokgöz, Ayşegül Zamani̇, Mahmut Selman Yildirim, Mehmet Si̇nan İyi̇soy
Turkish Journal of Medical Sciences
Background/aim: We aimed to investigate the associations between endothelial nitric oxide synthase(eNOS) gene polymorphisms [G894T (rs1799983)], intron 4 (27-bpTR) variable number tandem repeat (VNTR) and T786C (rs2070744), and ischemic stroke in the Anatolian population.Materials and methods: This case-control study included 112 patients with "stroke of undetermined etiology" and 160 controls. Real-time polymerase chain reaction (RT-PCR) analysis was used to analyze these polymorphisms. Between-group frequencies of alleles and genotypes were compared using binary logistic regression analysis.Results: No significant difference was observed between the two groups in terms of the genotype and allele distributions of the eNOS G894T (rs1799983) polymorphism (P > 0.05). …
Relationship Between The Earlobe Crease And Brain White Matter Abnormalities In Apparently Healthy Subjects*, Hati̇ce Ayça Ata Korkmaz
Relationship Between The Earlobe Crease And Brain White Matter Abnormalities In Apparently Healthy Subjects*, Hati̇ce Ayça Ata Korkmaz
Turkish Journal of Medical Sciences
Background/aim: In the present study we aimed to investigate whether the earlobe crease (ELC) might provide predictive information about white matter intensities (WMIs) in the brain that reflect brain aging.Materials and methods: A total of 350 individuals examined from January 2016 to July 2016 were screened. Patients with known demyelinating white matter disease, neurodegenerative disorders, cerebrovascular event history, or brain tumors were excluded from the study. Finally, 285 cases were included in the study. The four-point cerebral intensity classification system of Fazekas was used in the evaluation of the brain. The ELC was evaluated by inspection.Results: A total of 285 …
Results Of Home-Based Modified Combined Decongestive Therapy In Patients With Lower Extremity Lymphedema, Ali̇s Kostanoğlu, Meltem Ramoğlu, Ethem Güneren
Results Of Home-Based Modified Combined Decongestive Therapy In Patients With Lower Extremity Lymphedema, Ali̇s Kostanoğlu, Meltem Ramoğlu, Ethem Güneren
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to present the results of modified combined decongestive therapy (CDT) in patients with lower extremity lymphedema (LEL). Materials and methods: We retrospectively reviewed 95 patients aged 55.84 ± 15.70 years who had been diagnosed with LEL between May 2015 and May 2017. The patients were treated for 4 weeks with modified CDT, including self-manual lymphatic drainage, self-bandaging, decongestive exercises, and skin care.Results: The mean reduction amounts of edema volume before and after treatment were 296.05, 784.92, and 1038.50 mL for stages 1, 2, and 3 respectively (P = 0.001). There were significant differences …
Assessment Of Cardiac And Vessel Functions In Childhood Psoriasis, Berna Şaylan Çevi̇k, Fi̇gen Akalin, Eli̇f Erolu, Di̇lek Seçki̇n Gençosmanoğlu, Safi̇ye Atlas Tüli̇n Ergun
Assessment Of Cardiac And Vessel Functions In Childhood Psoriasis, Berna Şaylan Çevi̇k, Fi̇gen Akalin, Eli̇f Erolu, Di̇lek Seçki̇n Gençosmanoğlu, Safi̇ye Atlas Tüli̇n Ergun
Turkish Journal of Medical Sciences
Background/aim: Psoriasis is a chronic inflammatory disease. The effect of psoriasis on the cardiovascular system has not been studied in children before. We studied ventricular strain and vascular functions to assess early cardiovascular effects of psoriasis during childhood. Materials and methods: The study population consisted of 20 psoriatic and 20 age- and sex-matched control subjects. Two-dimensional echocardiography images, longitudinal and global strain, and carotid and brachial ultrasound studies were performed. Results: The mean age of psoriatic children was 14 ± 0.89 years and that of the controls was 14.05 ± 0.88. There were significant increases in terms of interventricular septum …
Antibiotic Resistance Pattern And Spa Types Of Staphylococcus Aureus Strains Isolated From Food Business And Hospital Kitchen Employees In Çanakkale, Turkey, Nesri̇n Çakici, Alper Akçali, Nükhet Ni̇lüfer Zorba
Antibiotic Resistance Pattern And Spa Types Of Staphylococcus Aureus Strains Isolated From Food Business And Hospital Kitchen Employees In Çanakkale, Turkey, Nesri̇n Çakici, Alper Akçali, Nükhet Ni̇lüfer Zorba
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine antibiotic resistance profiles and spa types of Staphylococcus aureus strains isolated from food business employees in Çanakkale, Turkey.Materials and methods:S.aureus isolates were collected from hand and nasal swabs of 300 individuals working in 17 food businesses and 9 hospital kitchens. All S. aureus isolates obtained from each carrier were typed by staphylococcal protein A (spa) typing method.Staphylococcal cassette chromosome mec (SCCmec) and multilocus sequence typing (MLST) of MRSA were performed by sequencing method.Results: Of the 300 individuals, 125 (41.6%) were found to be carriers of S. aureus, 215 isolates of which …
Analyzing The Effect Of Laparoscopy Duration Time On Peroperative Gastroesophageal Reflux, Gökhan Berktuğ Bahadir, Hakan Taşkinlar, Caner İsbi̇r, İsa Killi, Di̇lek Yünlüel, Ülkü Çömelekoğlu, Ali̇ Nayci
Analyzing The Effect Of Laparoscopy Duration Time On Peroperative Gastroesophageal Reflux, Gökhan Berktuğ Bahadir, Hakan Taşkinlar, Caner İsbi̇r, İsa Killi, Di̇lek Yünlüel, Ülkü Çömelekoğlu, Ali̇ Nayci
Turkish Journal of Medical Sciences
Background/aim: Intraabdominal pressure (IAP) is one of the main reasons for gastroesophageal reflux (GER). This study investigates whether IAP during laparoscopic surgery leads to GER in a time-dependent manner.Materials and methods: In a laparoscopy model, 15 mmHg IAP was created in 8 Wistar albino rats in the Trendelenburg position (TP). A 5 mm laparotomy was performed in the left lower abdominal region, and a 6 Fr catheter was placed intraabdominally. Air was insufflated into the abdominal cavity, and the pressure was kept constant at 15 mmHg. Esophageal pH alterations were measured by pH sticks for 4 h every 30 min.Results: …
Is Nocturnal Enuresis A Predisposing Factor For The Overactive Bladder?, Nicolaie Suditu, Irina Negru, Adelina Miron, Bogdan Novac, Catalin Ciuta
Is Nocturnal Enuresis A Predisposing Factor For The Overactive Bladder?, Nicolaie Suditu, Irina Negru, Adelina Miron, Bogdan Novac, Catalin Ciuta
Turkish Journal of Medical Sciences
Background/aim: This study aimed to perform a limited observational study to ascertain whether there is statistical support that nocturnal enuresis (NE) is a predisposing factor in the development of overactive bladder (OAB).Materials and methods: The authors recruited patients diagnosed with OAB over a period of twelve months, and those who declared a history of NE were asked additional questions regarding the features of their NE.Results: A total of 285 patients were diagnosed with overactive bladder, and 98 (34.38%) of them had previously displayed NE symptoms that had diminished before reaching the median age of 9.83. Separation of patients by sex …
A Pilot Study On The Beneficial Effects Of Additional Selenium Supplementation To Methimazole For Treating Patients With Graves' Disease, Bin Xu, Di Wu, Hong Ying, Ying Zhang
A Pilot Study On The Beneficial Effects Of Additional Selenium Supplementation To Methimazole For Treating Patients With Graves' Disease, Bin Xu, Di Wu, Hong Ying, Ying Zhang
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to assess the effect of a combination use of methimazole (MMI) and selenium (Se) in the treatment of Graves' disease (GD). Materials and methods: A total of 103 newly diagnosed hyperthyroidism patients were randomized to MMI and MMI + Se combination groups. After treatment for 6 months, the levels of triiodothyronine (FT3), free thyroxine (FT4), thyrotropin receptor antibody (TRAb), thyroid peroxidase antibody (TPOAb), and thyroglobulin antibody (TGAb) were observed. An in vitro culture model of thyroid cells was established and the protein expression and mRNA levels of TRAb, TPOAb, and TGAb were determined …
The Effect Of Medial Longitudinal Arch Height And Medial Longitudinal Arch Support Insoles On Postural Balance In Perimenopausal Women, Levent Karataş, Doğa Vuralli, Zafer Günendi̇
The Effect Of Medial Longitudinal Arch Height And Medial Longitudinal Arch Support Insoles On Postural Balance In Perimenopausal Women, Levent Karataş, Doğa Vuralli, Zafer Günendi̇
Turkish Journal of Medical Sciences
Background/aim: Changes in balance and postural control have been reported during the perimenopausal period. We investigated the effect of medial longitudinal arch height and medial arch support insoles on postural sway and balance in middle-aged perimenopausal women. Materials and methods: 29 women with normal arches and 29 women with low arches were included in the study. The foot arches of the participants were determined using the arch height index. The static balance index (SBI) measured by Kinesthetic Ability Trainer 3000 and functional reach test were used to evaluate postural balance. Measurements were obtained from all participants with and without medial …
Can Apelin Play A Role In The Etiology Of Tinnitus?, Nuray Ensari̇, Özer Erdem Gür, Ni̇lgün Gür, Ömer Tarik Selçuk, Levent Renda, Mustafa Deni̇z Yilmaz, Mehmet Türker Öztürk, Yeşi̇m Çeki̇n
Can Apelin Play A Role In The Etiology Of Tinnitus?, Nuray Ensari̇, Özer Erdem Gür, Ni̇lgün Gür, Ömer Tarik Selçuk, Levent Renda, Mustafa Deni̇z Yilmaz, Mehmet Türker Öztürk, Yeşi̇m Çeki̇n
Turkish Journal of Medical Sciences
Background/aim: Tinnitus is seen in 15% of the general population; in 1%-6% of this number, the quality of life is seriously affected by this chronic condition. Chemical, oxidative, and emotional stressors are important in terms of the clinical course of tinnitus. Apelin is an endogenous peptide which is an oxidative stress mediator. It has been shown that the apelin/APJ (apelin junction receptor) system plays various roles in the physiology and pathophysiology of many organs. However, the role of the apelin/APJ system as an oxidative stress mediator in tinnitus is unknown. We investigated the level of apelin in patients with normal …
Use Of Traditional And Complementary Medicine For Musculoskeletal Diseases, Güli̇s Kavadar, Sali̇ha Eroğlu Demi̇r, Ebru Ayteki̇n, Yildiz Akbal
Use Of Traditional And Complementary Medicine For Musculoskeletal Diseases, Güli̇s Kavadar, Sali̇ha Eroğlu Demi̇r, Ebru Ayteki̇n, Yildiz Akbal
Turkish Journal of Medical Sciences
Background/aim: We aimedto determine the prevalence of traditional and complementary medicine (TCM) use among patients with musculoskeletal disorders (MSDs) and to examine the methods used, frequency, and experienced benefits of therapies; the reasons for using TCM; and the sources of information about therapies. We also compared demographic characteristics of users and nonusers of TCM.Materials and methods: The descriptive study was conducted with 839 patients who attended the physical therapy and rehabilitation units of 3 public hospitals between September 2014 and March 2015. A self-administered questionnaire including demographic characteristics, medical history, and details of TCM use was applied. Results: Of the …
The Relationship Between Patellofemoral Arthritis And Fat Tissue Volume, Body Mass Index And Popliteal Artery Intima-Media Thickness Through 3t Knee Mri, Mehmet Kurt, Ali̇ Yusuf Öner, Murat Uçar, Seda Aladağ Kurt
The Relationship Between Patellofemoral Arthritis And Fat Tissue Volume, Body Mass Index And Popliteal Artery Intima-Media Thickness Through 3t Knee Mri, Mehmet Kurt, Ali̇ Yusuf Öner, Murat Uçar, Seda Aladağ Kurt
Turkish Journal of Medical Sciences
Background/aim: Evaluating the relationship of patellar chondromalacia with obesity, infrapatellar fat pad (IFP) volume and popliteal artery intima-media thickness (IMT).Materials and methods: A total of203 patients with different degree of patellar chondromalacia (103 male, 100 female) and 52 control subjects (19 male, 33 female) were included and grouped according to sex, age, body surface area (BSA), body mass index (BMI) and patellar chondromalacia classification. All measurements were completed with 3T magnetic resonance imaging (MRI). Articular cartilage and IFP volume were measured in saggital plane using double echo steady state (DESS) and DIXON sequences, respectively. Patellar cartilage damage was graded using …
Viral Prevalence, Clinical Profiles And Comparison Of Severity Scores For Predicting The Mortality Of Adults With Severe Acute Respiratory Infections, Hakan Aydin, Hali̇l Doğan, Doğaç Ni̇yazi̇ Özüçeli̇k, Mehmet Koçak, Osman Avşar Gül
Viral Prevalence, Clinical Profiles And Comparison Of Severity Scores For Predicting The Mortality Of Adults With Severe Acute Respiratory Infections, Hakan Aydin, Hali̇l Doğan, Doğaç Ni̇yazi̇ Özüçeli̇k, Mehmet Koçak, Osman Avşar Gül
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the accuracy of severity scores for predicting the 28-day mortality among adults with severe acute respiratory infection (SARI) admitted to the emergency department.Materials andmethods: This study included 159 consecutive adult patients with SARI admitted to the emergency department of a tertiary hospital. A standard form was filled out in order to record demographic information, clinical parameters, laboratory tests, and radiographic findings of the patients. CURB-65, PSI, SIRS, qSOFA, SOFA and APACHE II scores were compared between the survivor and nonsurvivor groups. Results: Of 159 patients included in the study, 38.4% were …
Evaluation Of Being Overweight/Obese And Related Sociodemographic Factors In 0-5 Year Age Group In Turkey: Turkey Demographic Health Survey 2013 Advanced Analysis, Asi̇ye Uğraş Di̇kmen, Hande Konşuk Ünlü, Lütfi̇ye Hi̇lal Özcebe
Evaluation Of Being Overweight/Obese And Related Sociodemographic Factors In 0-5 Year Age Group In Turkey: Turkey Demographic Health Survey 2013 Advanced Analysis, Asi̇ye Uğraş Di̇kmen, Hande Konşuk Ünlü, Lütfi̇ye Hi̇lal Özcebe
Turkish Journal of Medical Sciences
Background/aim: To determine risk factors of overweightness/obesity in children aged 0-5 years in the Turkish population.Materials and methods: We made advanced analysis using the Turkey Demographic Health Survey (TDHS) 2013 female database, in which data from children aged under five years and their mothers are included. Analyses were performed using weight for height index data. The children were divided into two groups by age as 0-23 months and 24-59 months.Results: The analysis comprised 2196 children aged under 5 years. Several factors were associated with an increase in overweightness/obesity of children aged under 5 years. Overweight/obesity in children aged 0-23 months …
Karnofsky Performance Scale Validity And Reliability Of Turkish Palliative Cancer Patients, Nagi̇han Yildiz Çeltek, Mustafa Süren, Osman Demi̇r, İsmai̇l Okan
Karnofsky Performance Scale Validity And Reliability Of Turkish Palliative Cancer Patients, Nagi̇han Yildiz Çeltek, Mustafa Süren, Osman Demi̇r, İsmai̇l Okan
Turkish Journal of Medical Sciences
Background/aim: Validated measures in palliative cancer patients are very important in the evaluation and management of the disease. The Karnofsky Performance Scale (KPS) has been used for many years to assess the performance status of cancer patients. The aim of this study is to determine the validity and reliability of the KPS in cancer patients receiving palliative care in Turkey.Materials and methods: Eighty patients with a cancer diagnosis who were admitted to Gaziosmanpaşa University Medical Faculty Hospital Palliative Care Unit between 01.03.2016 and 01.03.2017 were included in the study. KPS, measurements from the Katz Activi-ties of Daily Living (ADL) scale, …
Comparative Evaluation Of Liver, Spleen, And Kidney Stiffness In Hiv-Monoinfected Pediatric Patients Via Shear Wave Elastography, Emi̇ne Çalişkan, Gürkan Atay, Manolya Kara, Murat Sütçü, Zuhal Bayramoğlu, Selda Hançerli̇ Törün, Ayper Somer, İbrahi̇m Adaletli̇
Comparative Evaluation Of Liver, Spleen, And Kidney Stiffness In Hiv-Monoinfected Pediatric Patients Via Shear Wave Elastography, Emi̇ne Çalişkan, Gürkan Atay, Manolya Kara, Murat Sütçü, Zuhal Bayramoğlu, Selda Hançerli̇ Törün, Ayper Somer, İbrahi̇m Adaletli̇
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the stiffness of the liver, spleen, and kidneys in HIV-monoinfected children via shear wave elastography (SWE).Materials and methods: Twenty-one HIV-monoinfected children and 37 healthy subjects were included in this study. Livers, spleens, and kidneys of the participants were examined via ultrasound and SWE. Patients were divided into two groups according to the presence of pathologic ultrasonographic findings. Routine laboratory tests were also recorded. Stiffness of these organs was compared between patients and control groups.Results: Liver transaminases, blood urea, and creatinine levels were normal in all subjects. Ultrasonographic examination revealed hepatosplenomegaly (n = 1, 4.7%), …
Ovarian Stimulation Modalities In Poor Responders, Zehra Sema Özkan
Ovarian Stimulation Modalities In Poor Responders, Zehra Sema Özkan
Turkish Journal of Medical Sciences
In a group of IVF/ICSI cycles, despite the appropriate ovarian stimulation, the number of oocytes collected is below the expected value. This condition is defined as poor ovarian response (POR) to stimulation. POR brings the risk of cycle cancellation with an estimated rate of 20%. Infertility experts are trying to improve cycle outcomes of POR cases with multiple modifications. This review article will present the latest modifications on the management of POR. The studies performed for improving cycle outcome in POR cases were evaluated and their notable results were presented.The first intervention among infertility specialists is to make a standard …
Risk Factors For Coronary Artery Disease In Young Patients With Stable Angina Pectoris, Mustafa Duran, Deni̇z Elçi̇k, Sani̇ Namik Murat, Fati̇h Öksüz, İbrahi̇m Etem Çeli̇k
Risk Factors For Coronary Artery Disease In Young Patients With Stable Angina Pectoris, Mustafa Duran, Deni̇z Elçi̇k, Sani̇ Namik Murat, Fati̇h Öksüz, İbrahi̇m Etem Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: We aimed to investigate the relationship between risk factors and the presence of coronary artery disease (CAD) in a young population with stable angina pectoris (SAP).Materials and methods: A total of571 individuals younger than 60 years old, admitted to the outpatient clinic with chest pain and referred for coronary angiography between January 2015 and December 2017, were included in the study. All clinical and biochemical parameters were documented in the hospital records. Coronary angiography of patients was monitored from records. The individuals were divided into two groups. The patient group consisted of 363 individuals with at least one-vessel stenosis …
The Efficiency Of Low-Dose Hepatitis B Immunoglobulin Plus Nucleos(T)Ide Analogs In Preventing Posttransplant Hepatitis B Virus Recurrence, Sezgi̇n Vatansever, Rasim Ferecov, Hüseyi̇n Cahi̇t Yilmaz, Murat Zeytunlu, Murat Kiliç
The Efficiency Of Low-Dose Hepatitis B Immunoglobulin Plus Nucleos(T)Ide Analogs In Preventing Posttransplant Hepatitis B Virus Recurrence, Sezgi̇n Vatansever, Rasim Ferecov, Hüseyi̇n Cahi̇t Yilmaz, Murat Zeytunlu, Murat Kiliç
Turkish Journal of Medical Sciences
Background/aim: In this study, the efficiency of using low-dose hepatitis B immunoglobulin (HBIG) plus antiviral treatment according to individual needs has been evaluated in posttransplant hepatitis B virus (HBV) patients.Materials and methods: We retrospectively evaluated 179 patients who were admitted between 2009 and 2014. Five thousand IU intravenous HBIG was given in the anhepatic phase, and 400 IU/day intramuscular (IM) HBIG was given in the posttransplant period. After HBsAg seroconversion, 400 IU IM HBIG was continued as prophylaxis every two weeks.Results: The average follow-up period was 26 (2-65) months. Seventy patients had hepatocellular carcinoma (HCC). The HBV recurrence was 4.5% …
Prognostic Importance Of Pten, Egfr, Her-2, And Igf-1r In Gastric Cancer Patients Treated With Postoperative Chemoradiation, Berri̇n Benli̇ Yavuz, Mehmet Koç, Sümeyye Kozacioğlu, Gül Kanyilmaz, Meryem Aktan
Prognostic Importance Of Pten, Egfr, Her-2, And Igf-1r In Gastric Cancer Patients Treated With Postoperative Chemoradiation, Berri̇n Benli̇ Yavuz, Mehmet Koç, Sümeyye Kozacioğlu, Gül Kanyilmaz, Meryem Aktan
Turkish Journal of Medical Sciences
Background/aim: This study aimed to describe the prognostic importance of epidermal growth factor (EGFR), phosphatase and tensin homolog (PTEN), human EGF receptor-2 (HER-2), and insulin-like growth factor 1 receptor (IGF-1R) in gastric cancer patients treated with postoperative chemoradiation therapy. Materials and methods: Sixty-nine patients treated with adjuvant chemoradiation therapy were retrospectively evaluated. Tumor samples were stained immunohistochemically. Results: All patients were treated with 3D conformal radiation therapy with concomitant and adjuvant chemotherapy. Perineural invasion (PNI) (P = 0.042), prechemoradiation therapy albumin levels below 3.5 mg/dL (P = 0.011), and EGFR positivity (P = 0.008) had negative effects on overall survival …
Effect Of 4 Weeks Of Frankincense Consumption On Explicit Motor Memory And Serum Bdnf In Elderly Men, Elham Asadi, Mohammad Reza Shahabi Kaseb, Rasool Zeidabadi, Mohammad Reza Hamedinia
Effect Of 4 Weeks Of Frankincense Consumption On Explicit Motor Memory And Serum Bdnf In Elderly Men, Elham Asadi, Mohammad Reza Shahabi Kaseb, Rasool Zeidabadi, Mohammad Reza Hamedinia
Turkish Journal of Medical Sciences
Background/aim: Memory is a mechanism for coding, storing, and recalling information. Weak memory and learning disability are common psychological problems in the elderly. The aim of this study was to investigate the effect of 4 weeks of frankincense consumption on explicit motor memory and serum BDNF in the elderly.Materials and methods: Twenty elderly men (mean age of 60.2 ± 1.7 years) were randomly divided into two groups: experimental (n = 12) and placebo (n = 8). The first blood samples were collected 24 h before the pretest. Then both groups participated in a 4-week exercise program based on the protocol …
Anticipatory Effect Of Execution On Observation: An Approach Using Exopinch Finger Robot, Kutluk Bi̇lge Arikan, Hassan Gol Mohammad Zadeh, Ali̇ Emre Turgut, Murat Zi̇nnuroğlu, Gözde Bayer, Zafer Günendi̇, Bülent Cengi̇z
Anticipatory Effect Of Execution On Observation: An Approach Using Exopinch Finger Robot, Kutluk Bi̇lge Arikan, Hassan Gol Mohammad Zadeh, Ali̇ Emre Turgut, Murat Zi̇nnuroğlu, Gözde Bayer, Zafer Günendi̇, Bülent Cengi̇z
Turkish Journal of Medical Sciences
Background/aim: This study aims to explore the mirror neuron system (MNS) involvement using mu (8?12 Hz)/beta (15?25 Hz) band suppression in an action observation-execution paradigm. Materials and methods: Electrophysiological (EEG) data from 16 electrodes were recorded while 8 participants observed video clips of a hand squeezing a spring. Specifically, the effect of anticipated execution on observation was studied. For this purpose, a fully actuated finger exoskeleton robot was utilized to synchronize observation and execution and to control the execution condition for the partici-pants. Anticipatory effect was created with a randomized robot accompany session. Results: The results showed that the observational …
Relationship Between Sirt1 Gene Expression Level And Disease In Age-Related Cataract Cases, Ni̇hat Buğra Ağaoğlu, Nuray Varol, Sali̇ha Handan Yildiz, Cem Karaosmanoğlu, Rahmi̇ Duman, Müjgan Özdemi̇r Erdoğan, Mustafa Solak
Relationship Between Sirt1 Gene Expression Level And Disease In Age-Related Cataract Cases, Ni̇hat Buğra Ağaoğlu, Nuray Varol, Sali̇ha Handan Yildiz, Cem Karaosmanoğlu, Rahmi̇ Duman, Müjgan Özdemi̇r Erdoğan, Mustafa Solak
Turkish Journal of Medical Sciences
Background/aim: Age-related cataract is the most important visual impairment all over the world. Epigenetic modifications, especially overexpression of histone deacetylases, have become the focus of interest for cataract development in recent years. Sirtuin 1 (SIRT1), a class II histone deacetylase and a member of the sirtuin family, is one of the best-characterized histone deacetylases and has a pivotal role in age-related diseases. However, the association of SIRT1 with age-related cataracts has not yet been fully elucidated. Therefore, we aimed to determine the expression of SIRT1 in age-related cataract patients.Materials and methods: Expressions of SIRT1 were evaluated by quantitative polymerase chain …
Diaphragmatic Thickness In Chronic Obstructive Lung Disease And Relationship With Clinical Severity Parameters, Nalan Ogan, Yusuf Aydemi̇r, Togay Evri̇n, Gökçe Kaan Ataç, Ayşe Baha, Burak Kati̇poğlu, Banu Süzen, Evri̇m Eylem Akpinar
Diaphragmatic Thickness In Chronic Obstructive Lung Disease And Relationship With Clinical Severity Parameters, Nalan Ogan, Yusuf Aydemi̇r, Togay Evri̇n, Gökçe Kaan Ataç, Ayşe Baha, Burak Kati̇poğlu, Banu Süzen, Evri̇m Eylem Akpinar
Turkish Journal of Medical Sciences
Background/aim: Sonographic assessment of diaphragm structure and function would be a useful clinical tool in patients with chronic obstructive pulmonary disease (COPD). Our aim was to determine the muscle thickness of the diaphragm and the usefulness of clinical practice in patients with COPD.Materials and methods: The diaphragmatic thickness of 34 COPD patients and 34 healthy subjects was measured during tidal volume (Tmin) and deep inspiration (Tmax) on both sides using a B-mode ultrasound. The body mass index and the modified Medical Research Council (mMRC) index values were reported.Results: There was no correlation among TminR (P = 0.134), TminL (P = …