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Critically Ill Covid-19 Patient, Burçi̇n Halaçli, Akin Kaya, Arzu Topeli̇ İski̇t Jan 2020

Critically Ill Covid-19 Patient, Burçi̇n Halaçli, Akin Kaya, Arzu Topeli̇ İski̇t

Turkish Journal of Medical Sciences

Coronavirus disease 2019 (COVID-19) stands out as the major pandemic that we have experienced in the last century. As it affects every social structure, it brought the importance of intensive care support once again to the agenda of healthcare system after causing severe acute respiratory syndrome. The precautions to be taken against this virus, where our knowledge is extremely small, intensive care units take an indispensable place in pandemic planning. In this review, we aimed to emphasize the crucial points regarding intensive care management of COVID-19 patients, which we have written not only for intensivists but also for all healthcare …


Understanding Dynamics Of Pandemics, Levent Akin, Mustafa Gökhan Gözel Jan 2020

Understanding Dynamics Of Pandemics, Levent Akin, Mustafa Gökhan Gözel

Turkish Journal of Medical Sciences

Along the centuries, novel strain of virus such as influenza produces pandemics which increase illness, death and disruption in the countries. Spanish flu in 1918, Asian flu in 1957, Hong Kong flu in 1968 and swine flu in 2009 were known pandemic which had various characteristics in terms of morbidity and mortality. A current pandemic is caused by novel corona virus originated from China. COVID-19 pandemic is very similar to Spanish, Hong Kong, Asian and swine influenza pandemics in terms of spreading to world by the mobilized people. Burden of pandemic is considered in terms of disease transmissibility and the …


Sars-Cov-2 Epidemiology And Control, Different Scenarios For Turkey, Eskild Petersen, Ayşe Deni̇z Gökengi̇n Jan 2020

Sars-Cov-2 Epidemiology And Control, Different Scenarios For Turkey, Eskild Petersen, Ayşe Deni̇z Gökengi̇n

Turkish Journal of Medical Sciences

Background/aim: Coronavirus Infectious Disease 2019 (COVID-19) is now a pandemic spreading in most countries including Turkey. Materials and methods: The current knowledge of COVID-19 and the virus causing it, SARS-CoV-2, was reviewed. The epidemiology and control in different countries was compared and the differences discussed. Results: The population attack rates and case fatality rates vary from country to country with Lombardy in northern Italy reporting an attack rate in the general population of 0.37% compared to 0.004% in Hong Kong. The differences are caused by different testing strategies and reporting systems. Conclusion: Turkey is early in the outbreak. Different control …


Medical Mask Or N95 Respirator: When And How To Use?, Alpay Azap, Fatma Şebnem Erdi̇nç Jan 2020

Medical Mask Or N95 Respirator: When And How To Use?, Alpay Azap, Fatma Şebnem Erdi̇nç

Turkish Journal of Medical Sciences

COVID-19 pandemic is now a global threat to human health reaching up to 2 million infected people all around the world. Since its first recognition in Wuhan, many topics were discussed intensively about COVID-19, both in the public and scientific community. Personal protective equipment, especially masks, has been among the hottest topics during this pandemic. Regardless of which mask is used, performing hand hygiene frequently with an alcohol-based hand rub or with soap and water if hands are dirty is the most effective preventive measure for COVID-19. The type of mask used when caring for COVID-19 patients will vary according …


The Early Impact Of The Covid-19 Pandemic On The Global And Turkish Economy, Ömer Açikgöz, Asli Günay Jan 2020

The Early Impact Of The Covid-19 Pandemic On The Global And Turkish Economy, Ömer Açikgöz, Asli Günay

Turkish Journal of Medical Sciences

Background/aim: Individuals infected by the Covid-19 potentially are at risk of health and economic well-being. Today, the Covid-19 is a global issue, and the world economy can be interpreted as almost at the standstill. In this context, this study aims to discuss the potential first reactions of short and long term global economic impacts of the pandemic through sectors by assessing its costs according to the data announced for both the world and Turkey. In addition, this study tries to put forth possible economic and political scenarios for the post-pandemic world. Materials and methods: This is a review article that …


Global Surveillance, Travel, And Trade During A Pandemic, Ceren Çeti̇n, Ateş Kara Jan 2020

Global Surveillance, Travel, And Trade During A Pandemic, Ceren Çeti̇n, Ateş Kara

Turkish Journal of Medical Sciences

Pandemics have had very important consequences in human history. Lots of people lost their lives and countries have been intensively affected in terms of socioeconomic problems. Unfortunately, avoidance of pandemics and limiting the spread are still currently not always possible. Maybe the most important factor for this is the increasing frequency of traveling. Increasing airline traveling rate also increases the rate of spread. Global organizations like the World Health Organization and United Nations are trying to play a supreme role over the countries. Pandemics do not have borders; therefore, efforts should be given globally, definition of pandemic should be established …


Quarantine And Its Legal Dimension, Rahmi̇ Kiliç, Çi̇ğdem Ataman Hati̇poğlu, Cemi̇l Güneş Jan 2020

Quarantine And Its Legal Dimension, Rahmi̇ Kiliç, Çi̇ğdem Ataman Hati̇poğlu, Cemi̇l Güneş

Turkish Journal of Medical Sciences

Quarantine and isolation are public health measures used for centuries to prevent the spread of infectious diseases. Quarantine is separation of persons who have been exposed to an infection but asymptomatic, while isolation is separation of infected patients. Voluntary quarantine is preferred, but if necessary, it can be mandatory. These implementations can lead to restrictions on individual liberties, leading to ethical and legal problems. Isolation and quarantine enforcement are regulated by laws. Those who do not follow the quarantine rules could be punished. Isolation and quarantine practices in our country are described in General Hygiene Law. In this study the …


Coronaviruses And Sars-Cov-2, Mustafa Hasöksüz, Selçuk Kiliç, Fahri̇ye Saraç Jan 2020

Coronaviruses And Sars-Cov-2, Mustafa Hasöksüz, Selçuk Kiliç, Fahri̇ye Saraç

Turkish Journal of Medical Sciences

Coronaviruses (CoVs) cause a broad spectrum of diseases in domestic and wild animals, poultry, and rodents, ranging from mild to severe enteric, respiratory, and systemic disease, and also cause the common cold or pneumonia in humans. Seven coronavirus species are known to cause human infection, 4 of which, HCoV 229E, HCoV NL63, HCoV HKU1 and HCoV OC43, typically cause cold symptoms in immunocompetent individuals. The others namely SARS-CoV (severe acute respiratory syndrome coronavirus), MERS-CoV (Middle East respiratory syndrome coronavirus) were zoonotic in origin and cause severe respiratory illness and fatalities. On 31 December 2019, the existence of patients with pneumonia …


Epidemiology Of Covid-19, Cemal Bulut, Yasuyuki̇ Kato Jan 2020

Epidemiology Of Covid-19, Cemal Bulut, Yasuyuki̇ Kato

Turkish Journal of Medical Sciences

It seems that coronaviruses take an important place in the 21th century history. Five of seven human coronavirus was isolated in this century. Unfortunately, last three of them entered our life with a fear of outbreak, pandemic or death. Last human coronavirus which emerged world from Wuhan China, SARS CoV-2 and its clinical expression, Coronavirus disease (COVID-19) recently taken a significant place in our daily practice. Initial reports showed that, its origin was bats. It transmitted human to human by droplet and contact routes, but some doubt about airborne, fecal or intrauterine transmission also should be removed. Its R0 value …


Emerging And Reemerging Respiratory Viral Infections Up To Covid-19, İlhami̇ Çeli̇k, Esma Saatçi̇, Ayşegül Füsun Eyüboğlu Jan 2020

Emerging And Reemerging Respiratory Viral Infections Up To Covid-19, İlhami̇ Çeli̇k, Esma Saatçi̇, Ayşegül Füsun Eyüboğlu

Turkish Journal of Medical Sciences

Infectious diseases remain as the significant causes of human and animal morbidity and mortality, leading to extensive outbreaks and epidemics. Acute respiratory viral diseases claim over 4 million deaths and cause millions of hospitalizations in developing countries every year. Emerging viruses, especially the RNA viruses, are more pathogenic since most people have no herd immunity. The RNA viruses can adapt to the rapidly changing global and local environment due to the high error rate of their polymerases that replicate their genomes. Currently, coronavirus disease 2019 (COVID-19) is determined as an infectious disease caused by severe acute respiratory syndrome coronavirus 2 …


Novel Coronavirus Disease (Covid-19) In Children, Hasan Tezer, Tuğba Bedi̇r Demi̇rdağ Jan 2020

Novel Coronavirus Disease (Covid-19) In Children, Hasan Tezer, Tuğba Bedi̇r Demi̇rdağ

Turkish Journal of Medical Sciences

Coronavirus disease (COVID-19) was firstly reported at the end of 2019. The disease rapidly spread all around the world in a few months and was declared a worldwide pandemic by WHO in March 2020. By April 9, there were 1,436,198 confirmed COVID-19 cases in the world, nearly with 6% mortality rate. This novel infectious disease causes respiratory tract illness that may generally occur as mild upper respiratory tract disease or pneumonia. In older patients and/or patients with underlying conditions, it may result in acute respiratory distress syndrome, multi organ failure and even death. According to the current literature, children account …


Covid-19, Immune System Response, Hyperinflammation And Repurposingantirheumatic Drugs, Abdurrahman Tufan, Aslihan Avanoğlu Güler, Marco Matucci-Cerinic Jan 2020

Covid-19, Immune System Response, Hyperinflammation And Repurposingantirheumatic Drugs, Abdurrahman Tufan, Aslihan Avanoğlu Güler, Marco Matucci-Cerinic

Turkish Journal of Medical Sciences

In the Wuhan Province of China, in December 2019, the novel coronavirus 2019 (COVID-19) has caused a severe involvement of the lower respiratory tract leading to an acute respiratory syndrome. Subsequently, coronavirus 2 (SARS-CoV-2) provoked a pandemic which is considered a life-threatening disease. The SARS-CoV-2, a family member of betacoronaviruses, possesses singlestranded positive-sense RNA with typical structural proteins, involving the envelope, membrane, nucleocapsid and spike proteins that are responsible for the viral infectivity, and nonstructural proteins. The effectual host immune response including innate and adaptive immunity against SARS-Cov-2 seems crucial to control and resolve the viral infection. However, the severity …


Radiological Approaches To Covid-19 Pneumonia, Müşerref Şule Akçay, Tevfi̇k Özlü, Aydin Yilmaz Jan 2020

Radiological Approaches To Covid-19 Pneumonia, Müşerref Şule Akçay, Tevfi̇k Özlü, Aydin Yilmaz

Turkish Journal of Medical Sciences

COVID-19 pneumonia has high mortality rates. The symptoms are undiagnostic, the results of viral nucleic acid detection method (PCR) can delay, so that chest computerized tomography is often key diagnostic test in patients with possible COVID-19 pneumonia. In this review, we discussed the main radiological findings of this infection.


Covid-19: Pathogenesis, Genetic Polymorphism, Clinical Features And Laboratory Findings, Recep Öztürk Jan 2020

Covid-19: Pathogenesis, Genetic Polymorphism, Clinical Features And Laboratory Findings, Recep Öztürk

Turkish Journal of Medical Sciences

COVID-19 caused by a novel agent SARS-CoV-2 progressed to a pandemic condition and resulted in a major public health concern worldwide, leading to social and economic issues at the same time. The pathogenesis of COVID-19 starts with the bonding of the virus to ACE2 receptors expressed in many tissues, and the triggered excessive immune response plays a critical role in the course of the disease. The cytokine storm that occurs upon excessive production of pro-inflammatory cytokines is considered responsible for the severe progression of the disease and the organ damage. However, the accurate pathophysiological mechanism of the disease, which progresses …


Decreasing Incidence And Severity Of Behçet's Disease: A Changing Trend Inepidemiological Spectrum Possibly Associated With Oral Health, Gonca Mumcu, Fatma Ali̇baz Öner, Safi̇ye Atlas Tüli̇n Ergun, Rafi̇ Haner Di̇reskeneli̇ Jan 2020

Decreasing Incidence And Severity Of Behçet's Disease: A Changing Trend Inepidemiological Spectrum Possibly Associated With Oral Health, Gonca Mumcu, Fatma Ali̇baz Öner, Safi̇ye Atlas Tüli̇n Ergun, Rafi̇ Haner Di̇reskeneli̇

Turkish Journal of Medical Sciences

Behçet's disease (BD) is a systemic and inflammatory disorder that is mainly present along the ancient Silk Road, from the Mediterranean Sea to East Asia. A wide range of prevalence figures (0.1-420/100,000) have been reported for BD, also among Turkish populations of similar genetic background living in different countries. Recently, a decline in the incidence of BD and a change of the disease spectrum to less-severe manifestations have been reported from Japan and Korea, two genetically homogenous, affluent populations with limited immigration. It was hypothesized that a decline in infectious diseases, especially dental/periodontal infections, associated with the improvement in oral …


Total Oxidant And Antioxidant Status And Paraoxonase 1 Levels Ofchildren With Noncystic Fibrosis Bronchiectasis, Ahmet Hakan Gedi̇k, Erkan Çakir, Aysel Vehapoğlu Türkmen, Ömer Faruk Özer, Sare Betül Kaygusuz Jan 2020

Total Oxidant And Antioxidant Status And Paraoxonase 1 Levels Ofchildren With Noncystic Fibrosis Bronchiectasis, Ahmet Hakan Gedi̇k, Erkan Çakir, Aysel Vehapoğlu Türkmen, Ömer Faruk Özer, Sare Betül Kaygusuz

Turkish Journal of Medical Sciences

Background/aim: To evaluate total oxidant status (TOS), total antioxidant capacity (TAC), and paraoxonase 1 (PON1) levels in children with noncystic fibrosis (CF) bronchiectasis (BE), and to compare these levels with those of healthy controls. The study parameters were also evaluated according to some demographic, anthropometric, and clinical characteristics, as well as lung functions. Materials and methods: Enrolled in the study were 118 children with non-CF BE and 68 healthy controls. Serum TOS, TAC, and PON1 levels were determined. Lung function tests were performed by spirometry. Results: Serum TOS was higher in the patients [median 9.54 (IQR 25-75 = 7.05-13.30) µmol …


Effects Of Stage I Hypertension On The Recovery Of Early Postoperative Attention Network Function In Elderly Patients Undergoing Elective Hip Or Knee Arthroplasty Surgery, Dan Zhao, Jun Li, Rui Yang, Guanghong Xu Jan 2020

Effects Of Stage I Hypertension On The Recovery Of Early Postoperative Attention Network Function In Elderly Patients Undergoing Elective Hip Or Knee Arthroplasty Surgery, Dan Zhao, Jun Li, Rui Yang, Guanghong Xu

Turkish Journal of Medical Sciences

Background/aim: Hypertension is an important risk factor for cognitive impairment. This study explored whether elderly patients with stage I hypertension (HPs) and normotensive patients (NPs) showed differences in the recovery of postoperative attention network function according to the attentional network test (ANT) performance.Materials and methods: Of 110 patients screened, 25 HPs and 25 NPs completed this study. The Mini-Mental State Examination (MMSE) was applied to all participants before the operation and the ANT (on days 2 and 7) after the operation. All participants completed 1 day preoperatively and the ANT on postoperative days (PODs) 2 and 7.Results: Compared with NPs, …


Anti-Interleukin-6 (Tocilizumab) Therapy In Takayasu's Arteritis: A Real Life Experience, Levent Kiliç, Ömer Karadağ, Abdulsamet Erden, Alper Sari, Berkan Armağan, Gözde Kübra Yardimci, Esra Firat Şentürk, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Ali̇ Akdoğan Jan 2020

Anti-Interleukin-6 (Tocilizumab) Therapy In Takayasu's Arteritis: A Real Life Experience, Levent Kiliç, Ömer Karadağ, Abdulsamet Erden, Alper Sari, Berkan Armağan, Gözde Kübra Yardimci, Esra Firat Şentürk, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Ali̇ Akdoğan

Turkish Journal of Medical Sciences

Background/aim: Tumour necrosis factor inhibitors and anti-interleukin-6 (anti-IL-6) therapies are increasingly being used in Takayasu's arteritis (TA) patients who are unresponsive to corticosteroids ± conventional immunosuppressive agents.The aim of this study is to assess the efficacy and safety of anti-IL-6 (tocilizumab) therapy in refractory TA patients in real life.Materials and methods: Fifteen TA patients (86.7% were female) who received at least 3 cycles of tocilizumab therapy were retrospectively assessed by clinical, laboratory, and radiological evaluations before and after tocilizumab therapy. Results: The median (min-max) age of the patients at evaluation was 35 (20-58) years and the median disease duration from …


Dermoscopy Of Oral Mucocele: Three Types Of Extravasation Mucoceles, Erhan Ayhan, Serdar Feri̇t Toprak, Şeyhmus Kaya, Şeri̇ke Akkaynak Jan 2020

Dermoscopy Of Oral Mucocele: Three Types Of Extravasation Mucoceles, Erhan Ayhan, Serdar Feri̇t Toprak, Şeyhmus Kaya, Şeri̇ke Akkaynak

Turkish Journal of Medical Sciences

Background/aim: Dermoscopy is a diagnostic tool that assists in imaging the epidermis and dermis. Although it has also started to be used to diagnose nonmelanocytic lesions recently, it has not been tested much on oral mucosal masses, such as oral mucoceles. This study aimed to investigate whether dermoscopy is a valuable tool in diagnosing oral mucoceles.Materials and methods: In this study, the clinical and dermoscopic features of 21 oral mucocele lesions of 21 patients (11 females, 10 males) aged between 6 and 38 years who were confirmed histopathologically were evaluated.Results: Of the lesions studied, 95.2% (20) were extravasation and 4.8% …


Diagnostic Efficacy Of Routine Contrast-Enhanced Abdominal Ct For The Assessment Of Osteoporosis In The Turkish Population, Ayşegül Cansu, Di̇lara Atasoy, İlker Eyüboğlu, Murat Karkucak Jan 2020

Diagnostic Efficacy Of Routine Contrast-Enhanced Abdominal Ct For The Assessment Of Osteoporosis In The Turkish Population, Ayşegül Cansu, Di̇lara Atasoy, İlker Eyüboğlu, Murat Karkucak

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the diagnostic efficacy of vertebral Hounsfield unit (HU) values on routine contrast-enhanced abdominal computed tomography (CT) scans for the assessment of osteoporosis using dual-energy X-ray absorptiometry (DXA) T-scores as a reference standard.Materials and methods: A total of 111 consecutive patients who underwent contrast-enhanced abdominal CT examination for any indication and DXA within a 6-month period were retrospectively analyzed. The CT attenuation values of trabecular bone in HUs were measured in axial and sagittal planes from lumbar vertebrae 1-4 (L1-L4). The correlation between the DXA T-scores and HU values measured on the CT scans was …


Relationship Of Mesenteric Panniculitis With Visceral And Subcutaneous Adipose Tissue, Çi̇ğdem Özer Gökaslan, Eranil Aslan, Emi̇n Demi̇rel, Ayli̇n Yücel Jan 2020

Relationship Of Mesenteric Panniculitis With Visceral And Subcutaneous Adipose Tissue, Çi̇ğdem Özer Gökaslan, Eranil Aslan, Emi̇n Demi̇rel, Ayli̇n Yücel

Turkish Journal of Medical Sciences

Background/aim: Mesenteric panniculitis (MP) is an idiopathic benign disease characterized by fat necrosis, chronic inflammation, and fibrosis. The relationship between obesity and chronic low-grade inflammation has been reported. This study investigated the relationship of MP diagnosed using multidetector computed tomography (MDCT) with visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) areas.Materials and methods: We retrospectively enrolled 104 patients with no radiological findings other than MP. Additionally, 76 individuals without any indicative radiological findings were included as controls. VAT and SAT were separately calculated (cm2) using a 3-dimensional workstation. The abdominal circumference was measured (cm). Results: The mean abdominal circumference …


Twenty Children With Non-Wilms Renal Tumors From A Reference Center In Central Anatolia, Turkey, Ekrem Ünal, Ebru Yilmaz, Alper Özcan, Bi̇lgen Işik, Musa Karakükcü, Cüneyt Turan, Hülya Akgün, Fi̇gen Öztürk, Abdulhaki̇m Coşkun, Mehmet Aki̇f Özdemi̇r, Türkan Patiroğlu Jan 2020

Twenty Children With Non-Wilms Renal Tumors From A Reference Center In Central Anatolia, Turkey, Ekrem Ünal, Ebru Yilmaz, Alper Özcan, Bi̇lgen Işik, Musa Karakükcü, Cüneyt Turan, Hülya Akgün, Fi̇gen Öztürk, Abdulhaki̇m Coşkun, Mehmet Aki̇f Özdemi̇r, Türkan Patiroğlu

Turkish Journal of Medical Sciences

Background/aim: Non-Wilms renal tumors (NWRTs) are rarely encountered in children. The aim of this study is to determine the treatment strategies, prognosis, outcomes, and survival of children with NWRTs at Erciyes University in Kayseri, Turkey.Materials and methods: Medical records of all patients (n = 20) treated for NWRTs over a 23-year period (1995-2018) were reviewed retrospectively.Results: There was male predominance (female/male: 7/13); the median age at diagnosis was 3.2 years old (0.1-13.5 years old). The major histological groups included mesoblastic nephroma (MBN), (n: 5, 25%), malignant rhabdoid tumor (MRT), (n: 5, 25%), renal cell carcinoma, (n: 3, 15%), inflammatory myofibroblastic …


Predictive Factors For Treatment Success Of Transforaminal Epidural Steroid Injection In Lumbar Disc Herniation-Induced Sciatica, Savaş Şencan, Alp Eren Çelenli̇oğlu, Ruslan Asadov, Osman Hakan Gündüz Jan 2020

Predictive Factors For Treatment Success Of Transforaminal Epidural Steroid Injection In Lumbar Disc Herniation-Induced Sciatica, Savaş Şencan, Alp Eren Çelenli̇oğlu, Ruslan Asadov, Osman Hakan Gündüz

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to identify predictive factors for treatment success in transforaminal epidural steroid injection in patients with lumbar disc herniation-induced sciatica. Materials and methods: A total of 219 patients who were diagnosed with unilateral sciatica and underwent transforaminal epidural steroid injections at the level of L4-5, L5-S1, or S1 neural foramina between March 2016 and May 2018 were retrospectively analyzed. The presence of transitional vertebrae and the grade of nerve root compression were evaluated by a radiologist. Data including age, sex, body mass index, duration of symptoms, injection levels, and pain scores were recorded. Pain …


Patients With Copd Who Underwent Pulmonary Rehabilitation In Turkey: Prevalence, Distribution, And Mortality, Tarkan Özdemi̇r, İpek Candemi̇r, Pinar Ergün, Mustafa Hami̇dullah Türkkani, Orhan Koç Jan 2020

Patients With Copd Who Underwent Pulmonary Rehabilitation In Turkey: Prevalence, Distribution, And Mortality, Tarkan Özdemi̇r, İpek Candemi̇r, Pinar Ergün, Mustafa Hami̇dullah Türkkani, Orhan Koç

Turkish Journal of Medical Sciences

Background: Pulmonary rehabilitation (PR) is an effective, evidenced-based treatment. Despite its proven effect, it is still underused. The aim of this study was to present the number of patients with chronic obstructive pulmonary disease (COPD) who underwent PR, general mortality percentages, the rate of patients prescribed PR by pulmonologists, and the distribution of institutions where PR was performed between 2008 and 2016 in Turkey. Materials and methods: The documents were obtained from Turkish Institution of Social Insurance. Ages, sexes, and numbers of patients with COPD who underwent PR between 2008 and 2016 were recorded. The number of patients with COPD …


Can Postoperative Pain Be Predicted? New Parameter: Analgesia Nociception Index, Ali̇ Şefi̇k Köprülü, Ali̇ Haspolat, Yaşar Gökhan Gül, Nurşen Tanrikulu Jan 2020

Can Postoperative Pain Be Predicted? New Parameter: Analgesia Nociception Index, Ali̇ Şefi̇k Köprülü, Ali̇ Haspolat, Yaşar Gökhan Gül, Nurşen Tanrikulu

Turkish Journal of Medical Sciences

Background/aim: The Analgesia Nociception Index (ANI) is a new method of identifying nociception-analgesia balance. In this study, we investigate the correlation between the ANI and numeric rating scale (NRS) values immediately before and after extubation. The NRS values were recorded in the postanesthesia care unit, in a group of patients who underwent laparoscopic cholecystectomy, with the aim of evaluating the potential use of ANI values in the prediction of postoperative pain levels.Materials and methods: The ANI and NRS values, heartbeat rate (HR), systolic and diastolic arterial pressure (SAP/DAP), and oxygen saturation (SpO2) values of the patients were recorded into three …


Evaluation Of A Two-Image Technique Consisting Of An Axial And A Coronal Image Generated By Using The Rib-Flattening Application: Effect On Reading Time And Diagnostic Validity, Hüseyi̇n Koray Kiliç, Meli̇h Akyüz, Emetullah Ci̇ndi̇l, Nesri̇n Erdoğan, Gonca Erbaş, Mehmet Araç Jan 2020

Evaluation Of A Two-Image Technique Consisting Of An Axial And A Coronal Image Generated By Using The Rib-Flattening Application: Effect On Reading Time And Diagnostic Validity, Hüseyi̇n Koray Kiliç, Meli̇h Akyüz, Emetullah Ci̇ndi̇l, Nesri̇n Erdoğan, Gonca Erbaş, Mehmet Araç

Turkish Journal of Medical Sciences

Background/aim: When reading a chest CT, a radiologist needs to evaluate each rib one by one due to complex curvy shape, which makes reporting a tiresome and time-consuming task. A new curved planar reformat application that flattens ribs on a single plane may find a place in the radiology reporting room. This study aimed to evaluate the effect of a two-image set created by using the rib-flattening application on the performance of a radiologist in detecting sclerotic rib lesions in cancer patients. Materials and methods: The local Institutional Review Board approved this retrospective study.Two radiologists with different experience levels reviewed …


Severe Neonatal Hyperbilirubinemia In The Southeast Region Of Turkey, Özlem Bozkurt, Ebru Yücesoy, Baran Oğuz, Ömür Akinel, Mehmet Fati̇h Palali, Nurgül Ataş Jan 2020

Severe Neonatal Hyperbilirubinemia In The Southeast Region Of Turkey, Özlem Bozkurt, Ebru Yücesoy, Baran Oğuz, Ömür Akinel, Mehmet Fati̇h Palali, Nurgül Ataş

Turkish Journal of Medical Sciences

Background/aim: Severe neonatal hyperbilirubinemia is an important cause of morbidity and mortality in developing countries. The aim was to assess etiologic reasons for development of severe hyperbilirubinemia and define risk factors for exchange transfusion and acute bilirubin encephalopathy (ABE) in Şanlıurfa located in the southeast region of Turkey.Materials and methods: An observational cohort study included 115 infants with ≥35 weeks of gestation admitted with diagnosis of severe hyperbilirubinemia in a period of 18 months. Potential risk factors associated with exchange transfusion and development of ABE were analyzed.Results: Among 115 infants, 67 (58.3%) received exchange transfusion and 45 (39.1%) developed ABE. …


Thiol/Disulfide Homeostasis And Ischemia Modified Albumin Levels In Autoimmune Gastritis And Their Relations With Gastric Emptying, Emra Asfuroğlu Kalkan, Serap Boz, Özcan Erel, Sali̇m Neşeli̇oğlu, Çağdaş Kalkan, Ari̇f İrfan Soykan Jan 2020

Thiol/Disulfide Homeostasis And Ischemia Modified Albumin Levels In Autoimmune Gastritis And Their Relations With Gastric Emptying, Emra Asfuroğlu Kalkan, Serap Boz, Özcan Erel, Sali̇m Neşeli̇oğlu, Çağdaş Kalkan, Ari̇f İrfan Soykan

Turkish Journal of Medical Sciences

Background/aim: Autoimmune gastritis is an autoimmune and inflammatory disorder. The aim of this study is to examine dynamic thiol/disulfide homeostasis and ischemia modified albumin levels, and to analyze the association between thiol/disulfide homeostasis and gastric emptying time in autoimmune gastritis. Materials and methods: Thiol/disulfide homeostasis tests and ischemia modified albumin levels were determined in 50 autoimmune gastritis patients and 53 healthy subjects. Patients with delayed and normal gastric emptying were compared by thiol/disulfide homeostasis tests. Results: The results showed that native thiol (μmol/L), total thiol (μmol/L), and native thiol/total thiol ratio (%) of the patients with autoimmune gastritis decreased compared …


Effects Of Early Mobilization And Weight Bearing On Postoperative Walking Ability And Pain In Geriatric Patients Operated Due To Hip Fracture: A Retrospective Analysis, Tolgahan Kuru, Haci Ali̇ Olçar Jan 2020

Effects Of Early Mobilization And Weight Bearing On Postoperative Walking Ability And Pain In Geriatric Patients Operated Due To Hip Fracture: A Retrospective Analysis, Tolgahan Kuru, Haci Ali̇ Olçar

Turkish Journal of Medical Sciences

Background/aim: Hip fractures in older adults are associated with high morbidity, mortality, and subsequent hospital costs and decreased quality of life. The objective of this study was to evaluate geriatric patients who underwent partial prosthesis surgery following hip fracture and effects of early mobilization and weight bearing on postoperative walking ability and pain. Materials and methods: A total of 52 geriatric patients with intertrochanteric and femoral neck fractures were included in the study. Patients' service files, system records, pre- and postoperative X-rays were retrospectively reviewed.Results: There were 52 patients in the study group with 36 (69.2%) being female. The mean …


Addition Of Intratympanic Steroid Or Hyperbaric Oxygen Treatment To Systemic Steroid Treatment In Sudden Idiopathic Sensorineural Hearing Loss Treatment, And Long-Term Results Of Salvage Treatment, Kemal Keseroğlu, Gökhan Toptaş, Ahmet Uluat, Ömer Bayir, Emel Çadalli Tatar, Güleser Saylam, Mehmet Hakan Korkmaz, Ali̇ Özdek Jan 2020

Addition Of Intratympanic Steroid Or Hyperbaric Oxygen Treatment To Systemic Steroid Treatment In Sudden Idiopathic Sensorineural Hearing Loss Treatment, And Long-Term Results Of Salvage Treatment, Kemal Keseroğlu, Gökhan Toptaş, Ahmet Uluat, Ömer Bayir, Emel Çadalli Tatar, Güleser Saylam, Mehmet Hakan Korkmaz, Ali̇ Özdek

Turkish Journal of Medical Sciences

Background/aim: This study aims to determine the therapeutic superiority of the addition of intratympanic steroid or hyperbaric oxygen therapy to systemic steroid treatment in idiopathic sudden sensorineural hearing loss as initial treatment, and evaluate the long-term results of salvage treatment. Materials and methods: This study was a retrospective clinical trial with a total of 96 patients with idiopathic sudden sensorineural hearing loss. Patients were divided into 3 groups. Group 1 (n: 32) received systemic steroid treatment. Group 2 (n: 32) received the Group 1 protocol plus intratympanic steroid treatment. Group 3 (n: 32) received the Group 1 protocol plus hyperbaric …