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Articles 1441 - 1470 of 4871
Full-Text Articles in Medicine and Health Sciences
Covid-19-Related Anxiety In People Living With Hiv: An Online Cross-Sectional Study, Özlem Kuman Tunçel, Hüsnü Pullukçu, Hüseyi̇n Aytaç Erdem, Behi̇ce Kurtaran, Seli̇n Ece Taşbakan, Meltem Taşbakan
Covid-19-Related Anxiety In People Living With Hiv: An Online Cross-Sectional Study, Özlem Kuman Tunçel, Hüsnü Pullukçu, Hüseyi̇n Aytaç Erdem, Behi̇ce Kurtaran, Seli̇n Ece Taşbakan, Meltem Taşbakan
Turkish Journal of Medical Sciences
Background/aim: The emergence of the coronavirus disease 2019 (COVID-19) outbreak has had an enormous emotional impact on some vulnerable groups, such as people living with human immunodeficiency virus (HIV) (PLHIV). This study was planned with the aim of assessing the anxiety levels of PLHIV and the sources of their anxiety. Materials and methods: A web-based questionnaire was sent to PLHIV using the virtual snowball sampling method. The questionnaire included questions about sociodemographic status, information about HIV infection, and the Beck Anxiety Inventory (BAI). Additionally, some opinions of the participants about COVID-19 were asked. Results: A total of 307 respondents, with …
Covid-19 Experience Of The Major Pandemic Response Center In The Capital: Results Ofthe Pandemic's First Month In Turkey, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Bi̇rcan Kayaaslan, Adalet Aypak, Ayşe Kaya Kalem, Fatma Eser, Burcu Özdemi̇r, Eli̇f Muki̇me Saricaoğlu, Müge Ayhan, Yeşi̇m Aybar Bi̇li̇r, Işil Özkoçak Turan, Deni̇z Erdem, Nevzat Mehmet Mutlu, Turan Buzğan, Bedi̇a Di̇nç
Covid-19 Experience Of The Major Pandemic Response Center In The Capital: Results Ofthe Pandemic's First Month In Turkey, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Bi̇rcan Kayaaslan, Adalet Aypak, Ayşe Kaya Kalem, Fatma Eser, Burcu Özdemi̇r, Eli̇f Muki̇me Saricaoğlu, Müge Ayhan, Yeşi̇m Aybar Bi̇li̇r, Işil Özkoçak Turan, Deni̇z Erdem, Nevzat Mehmet Mutlu, Turan Buzğan, Bedi̇a Di̇nç
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to evaluate the epidemiological and clinical characteristics and parameters that determined the clinical course and prognosis of the COVID-19 patients admitted to Ankara City Hospital during the first month of the pandemic in Turkey. Materials and methods: SARS-CoV-2 PCR positive patients who were hospitalized between March 10 and April 10, 2020 were included. Results: Among 222 patients, mean age was higher in severe acute respiratory illness (SARI)/critical disease group (P < 0.001). Median time from illness onset to admission and presence of comorbidity, especially coronary artery disease and chronic obstructive pulmonary disease, were significantly higher in the SARI/critical disease group (P < 0.05). Cough and fever were the most common symptoms, while anosmia and loss of taste were observed in 8.6% and 7.7% patients, respectively. The mortality rate was 5.4%. A high neutrophil/lymphocyte ratio; low lymphocyte, monocyte, and platelet count; elevated liver enzymes; low GFR; and high levels of muscle enzymes, ferritin, and IL-6 on admission were found to be associated with SARI/critical disease (P < 0.05). Bilateral ground-glass opacity and patchy infiltration were more frequently seen in the SARI/critical disease group (P < 0.001). Patients older than 65 years had an 8-fold increased risk for development of SARI/critical disease. Conclusion: This cohort study regarding COVID-19 cases in Turkey reveals that older age, presence of comorbidity, bilateral infiltration on CT, high neutrophil/lymphocyte ratio, low monocyte and platelet count, elevated liver enzymes, low GFR, high levels of muscle enzymes, and high levels of ferritin and IL-6 on admission are predictors of SARI and severe disease.
Survival Analysis And Factors Affecting Survival In Patients Who Presented To The Medicaloncology Unit With Non-Small Cell Lung Cancer, Özgür Önal, Murat Koçer, Hande Nur Eroğlu, Servet Derya Yilmaz, İsmet Eroğlu, Di̇lek Karadoğan
Survival Analysis And Factors Affecting Survival In Patients Who Presented To The Medicaloncology Unit With Non-Small Cell Lung Cancer, Özgür Önal, Murat Koçer, Hande Nur Eroğlu, Servet Derya Yilmaz, İsmet Eroğlu, Di̇lek Karadoğan
Turkish Journal of Medical Sciences
Background/aim: This study aimed to investigate the effect of clinical and pathological indicators at the time of the diagnosis on overall survival in patients recently diagnosed with non-small cell lung cancer. Materials and methods: The study population consisted of patients who were diagnosed at the Faculty of Medicine at Isparta Süleyman Demirel University Hospital between January 1, 2010 and December 31, 2017 and presented to the medical oncology outpatient clinic. Results: A total of 518 patients were evaluated, including 260 patients with squamous cell carcinoma, 207 patients with adenocarcinoma, 50 patients with non-small cell lung cancer-not otherwise specified, and 1 …
Effects Of Immunization Program On Morbidity And Mortality Rates Ofvaccine-Preventable Diseases In Turkey, Tufan Nayi̇r, Ersi̇n Nazlican, Musa Şahi̇n, Fati̇h Kara, Emi̇ne Alp Meşe
Effects Of Immunization Program On Morbidity And Mortality Rates Ofvaccine-Preventable Diseases In Turkey, Tufan Nayi̇r, Ersi̇n Nazlican, Musa Şahi̇n, Fati̇h Kara, Emi̇ne Alp Meşe
Turkish Journal of Medical Sciences
Background/aim: This study aims to serve as a unique consolidated source in Turkey's vaccination history and as an example for other countries by objectively revealing the change in mortality and morbidity rates in Turkey following the beginning of vaccination without asserting any claim on the benefits or risks of vaccines. This unbiased research will also help health professionals identify the challenges more easily when they face with the people who hesitate to vaccinate their children. Materials and methods: Descriptive research design is adopted in this study. The coverages of vaccinations, mortality, and morbidity rates were identified through a retrospective analysis …
Correlation Between Serum Vitamin D Level And Dichotomous Distribution Ofhematological Parameters In A Cohort Of 12709 Patients, Oktay Olmuşçeli̇k, Ömür Gökmen Sevi̇ndi̇k
Correlation Between Serum Vitamin D Level And Dichotomous Distribution Ofhematological Parameters In A Cohort Of 12709 Patients, Oktay Olmuşçeli̇k, Ömür Gökmen Sevi̇ndi̇k
Turkish Journal of Medical Sciences
Background/aim: Recent evidence suggests that Vitamin D deficiency may be associated with varying degrees of peripheral blood cytopenia(s). However, the effect of Vitamin D on hematopoiesis is largely unknown. According to predefined inclusion criteria, here we analyzed the correlation between serum Vitamin D level and hematological parameters. Materials and methods: In the present cohort study, a total of 12.709 patients were screened. In the first data set, all patients were included. However, in the second one, only patients (9.936) with no complete blood count (CBC) abnormality and any nutritional deficiency (Iron, Vitamin B12 and Folic acid) were evaluated. According to …
Serum Paraoxonase 1 And 3 Activities In Benign And Malignant Diseases Of The Prostateand Changes In Levels Following Robotic-Assisted Laparoscopic Radical Prostatectomy, Fevzi̇ Bedi̇r, Hüseyi̇n Kocatürk, Mehmet Sefa Altay, Engi̇n Şebi̇n, Banu Bedi̇r
Serum Paraoxonase 1 And 3 Activities In Benign And Malignant Diseases Of The Prostateand Changes In Levels Following Robotic-Assisted Laparoscopic Radical Prostatectomy, Fevzi̇ Bedi̇r, Hüseyi̇n Kocatürk, Mehmet Sefa Altay, Engi̇n Şebi̇n, Banu Bedi̇r
Turkish Journal of Medical Sciences
Background/aim: This study aimed to examine serum paraoxonase 1 and 3 (PON1 and PON3) activities in benign and malignant diseases of the prostate, to determine lipid profile and malondialdehyde (MDA) levels, and to investigate changes in levels following robotic-assisted laparoscopic radical prostatectomy (RALRP). Materials and methods: A total of 137 patients, including a control group, were enrolled in the study and assigned into four groups. Group 1 (n = 33) consisted of patients previously undergoing RALRP with no recurrence, group 2 (n = 36) consisted of patients diagnosed with prostate cancer (PCa) and undergoing RALRP, and group 3 (n = …
Rare Occurrence Of Common Filaggrin Mutations In Turkish Children With Food Allergyand Atopic Dermatitis, Neşe Vardar Acar, Özlem Cavkaytar, Ebru Arik Yilmaz, Ayşe Betül Büyükti̇ryaki̇, Özge Uysal Soyer, Ümi̇t Murat Şahi̇ner, Bülent Eni̇s Şekerel, İbrahi̇m Çağatay Karaaslan, Cansin Saçkesen
Rare Occurrence Of Common Filaggrin Mutations In Turkish Children With Food Allergyand Atopic Dermatitis, Neşe Vardar Acar, Özlem Cavkaytar, Ebru Arik Yilmaz, Ayşe Betül Büyükti̇ryaki̇, Özge Uysal Soyer, Ümi̇t Murat Şahi̇ner, Bülent Eni̇s Şekerel, İbrahi̇m Çağatay Karaaslan, Cansin Saçkesen
Turkish Journal of Medical Sciences
Background/aim: Filaggrin is a protein complex involved in epidermal differentiation and skin barrier formation. Mutations of the filaggrin gene (FLG) are associated with allergen sensitization and allergic diseases like atopic dermatitis (AD), allergic rhinitis, food allergy (FA), and asthma. The aim of the study is to reveal the frequency of change in the FLG gene and determine the association between FLG loss-of-function (LOF) mutations and FA and/or AD in Turkish children. Materials and methods: Four FLG loss-of-function (LOF) mutations known to be common in European populations were analyzed in 128 healthy children, 405 food-allergic children with or without atopic dermatitis, …
Cross-Sectional Study: Long Term Follow-Up Care For Pediatric Cancer Survivors In Adeveloping Country, Turkey: Current Status, Challenges, And Future Perspectives, Sonay İncesoy Özdemi̇r, Nurdan Taçyildiz, Ali̇ Varan, Reji̇n Kebudi̇, Osman Bülent Zülfi̇kar, Tüli̇n Tiraje Celkan, Gürses Şahi̇n, Funda Vesi̇le Çorapcioğlu, Zuhal Keski̇n Yildirim, Faruk Güçlü Pinarli, Hati̇ce Nur Olgun, Neriman Sari, Ayhan Dağdemi̇r, Derya Özyörük, Tuba Eren
Cross-Sectional Study: Long Term Follow-Up Care For Pediatric Cancer Survivors In Adeveloping Country, Turkey: Current Status, Challenges, And Future Perspectives, Sonay İncesoy Özdemi̇r, Nurdan Taçyildiz, Ali̇ Varan, Reji̇n Kebudi̇, Osman Bülent Zülfi̇kar, Tüli̇n Tiraje Celkan, Gürses Şahi̇n, Funda Vesi̇le Çorapcioğlu, Zuhal Keski̇n Yildirim, Faruk Güçlü Pinarli, Hati̇ce Nur Olgun, Neriman Sari, Ayhan Dağdemi̇r, Derya Özyörük, Tuba Eren
Turkish Journal of Medical Sciences
Aim: The main purpose of this study is to determine the current status of long-term follow-up (LTFU) for childhood cancer survivors and the challenges of LTFU for pediatric cancer survivors at pediatric oncology institutions in Turkey. Material and methods: A questionnaire was e-mailed to the directors of 33 pediatric oncology centers (POCs) registered in the Turkish Pediatric Oncology Group (TPOG). Of these 33 active TPOG institutions, 21 participated in the study and returned their completed questionnaires. Results: Only 1 of the 21 participating centers had a separate LTFU clinic. The remaining centers provided LTFU care for childhood cancer survivors at …
Validity And Reliability Of The Turkish Version Of The Multidimensional Dyspnea Profile Inoutpatients With Respiratory Disease, Buse Özcan Kahraman, Turhan Kahraman, İsmai̇l Özsoy, Ayli̇n Tanriverdi̇, Asli Papurcu, Nazeni̇n Hande Sezgi̇n, Karya Polat, Serap Acar, Ayli̇n Özgen Alpaydin, Can Sevi̇nç, Sema Savci
Validity And Reliability Of The Turkish Version Of The Multidimensional Dyspnea Profile Inoutpatients With Respiratory Disease, Buse Özcan Kahraman, Turhan Kahraman, İsmai̇l Özsoy, Ayli̇n Tanriverdi̇, Asli Papurcu, Nazeni̇n Hande Sezgi̇n, Karya Polat, Serap Acar, Ayli̇n Özgen Alpaydin, Can Sevi̇nç, Sema Savci
Turkish Journal of Medical Sciences
Background/aim: Dyspnea is the subjective feeling of breathing discomfort, which is a significant problem for patients with heart and respiratory disease and also an important determinant of exercise tolerance, quality of life, and mortality in various diseases. Most of the scales are not enough to investigate the multidimensional effects of dyspnea; therefore, the Multidimensional Dyspnea Profile (MDP) was developed and validated in many languages. This study aimed to translate and culturally adapt the MDP into Turkish and investigate the psychometric properties of this adapted version in outpatients with respiratory disease. Materials and methods: The MDP was translated and culturally adapted …
Genetic Evaluation Of Mycobacterium Bovis Isolates With Miru-Vntr And Spoligotyping, Nevi̇n Tuzcu, Fati̇h Köksal
Genetic Evaluation Of Mycobacterium Bovis Isolates With Miru-Vntr And Spoligotyping, Nevi̇n Tuzcu, Fati̇h Köksal
Turkish Journal of Medical Sciences
Background/aim: Determining the epidemiological characteristics of M. bovis strains isolated from human and animal tuberculosis cases will assist in taking more appropriate and effective control measures in controlling tuberculosis originating from animals. Materials and methods: In this study, 32 M. bovis isolates of animal origin and 10 of human origin were isolated and identified in the Çukurova region between March 2011 and June 2012. The 12-locus MIRU-VNTR and spoligotyping methods were used. Results: Six different patterns were determined by spoligotyping and 10 by MIRU-VNTR. When both methods were used together, the number of patterns was found to be 28; MIRU4, …
Iron Homeostasis Is Altered In Response To Hypoxia And Hypothermic Preconditioning Inbrain Glial Cells, Lati̇fe Arzu Aral, Mehmet Ali̇ Ergün, Ayşe Başak Engi̇n, Alp Özgün Börcek, Hayrunni̇sa Bolay Belen
Iron Homeostasis Is Altered In Response To Hypoxia And Hypothermic Preconditioning Inbrain Glial Cells, Lati̇fe Arzu Aral, Mehmet Ali̇ Ergün, Ayşe Başak Engi̇n, Alp Özgün Börcek, Hayrunni̇sa Bolay Belen
Turkish Journal of Medical Sciences
Background/aim: Altered iron metabolism is one of the pathophysiological mechanisms occurring during hypoxic injuries in the central nervous system. Proper homeostasis of cellular iron is regulated by iron import, storage, and export proteins that prevent excess iron overload or iron starvation in cells. Therapeutic hypothermia is an approved treatment for hypoxic ischemia in newborns, but the underlying molecular mechanism is still unknown. We studied the effects of hypoxia, preceded with preconditioning, on the iron homeostasis of glial cells, known as a major actor in the inflammatory process during perinatal brain injury. Materials and methods: Primary microglia and astrocytes in culture …
Clinical And Demographic Characteristics Of Children And Adolescents With Acute Vertigosymptoms: A Cross-Sectional Study, Arzu Yilmaz, Sema Ni̇lay Abseyi̇
Clinical And Demographic Characteristics Of Children And Adolescents With Acute Vertigosymptoms: A Cross-Sectional Study, Arzu Yilmaz, Sema Ni̇lay Abseyi̇
Turkish Journal of Medical Sciences
Background/aim: Vertigo is one of the rarely diagnosed disorders during childhood due to insufficient description of the children regarding their experiences to the physicians. The clinical features of children and adolescents admitted by acute vertigo symptoms were investigated to elaborate the subject retrospectively. Materials and methods: Between January 2017-July 2019, records of cases admitted with acute vertigo complaints to pediatric neurology were retrospectively examined. Results: Of 761 patients, mean age was 13.8 years, 64% (n = 487) were women, 22.6% (n = 172) of which were children (1-11 years). A total of 37.3% of the cases (n = 284) had …
Effects Of Different Epidural Initiation Volumes On Postoperative Analgesia In Cesarean Section, Osman Kaçmaz, Nurçi̇n Gülhaş, Gülay Erdoğan Kayhan, Mahmut Durmuş
Effects Of Different Epidural Initiation Volumes On Postoperative Analgesia In Cesarean Section, Osman Kaçmaz, Nurçi̇n Gülhaş, Gülay Erdoğan Kayhan, Mahmut Durmuş
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to compare the effects of different epidural initiation volumes on postoperative pain scores, analgesic requirements, and side effects in pregnant women administered patient-controlled epidural analgesia (PCEA) for postoperative pain after cesarean sections. Materials and methods: Eighty-one pregnant women, aged 18-45 years, were included in this randomized, double-blind study. Combined spinal epidural anesthesia was administered for each cesarean section. The patients were divided into 3 groups and different volumes (20 mL, 10 mL, and 5 mL) of the study drug (0.0625% bupivacaine plus 2 μg/mL of fentanyl) were administered 90 min after the spinal …
Comparing Performance Of Mcgrath Mac Videolaryngoscope In Morbidly Obese Andnonobese Patients, Ying Gao, Liu-Jia-Zi Shao, Fushan Xue
Comparing Performance Of Mcgrath Mac Videolaryngoscope In Morbidly Obese Andnonobese Patients, Ying Gao, Liu-Jia-Zi Shao, Fushan Xue
Turkish Journal of Medical Sciences
No abstract provided.
Antioxidative Effects Of Uridine In A Neonatal Rat Model Of Hyperoxic Brain Injury, Nevi̇n Al, Ayşen Çakir, Cansu Sevi̇nç, Mehmet Cansev, Tüli̇n Alkan
Antioxidative Effects Of Uridine In A Neonatal Rat Model Of Hyperoxic Brain Injury, Nevi̇n Al, Ayşen Çakir, Cansu Sevi̇nç, Mehmet Cansev, Tüli̇n Alkan
Turkish Journal of Medical Sciences
Background/aim: Premature birth is a major problem that results in an increased risk of mortality and morbidity. The management of such infants consists of supraphysiological oxygen therapy, which affects brain development due, in part, to the deterioration caused by reactive oxygen species (ROS). We showed previously that exogenously administered uridine provides neuroprotection in a neonatal rat model of hyperoxic brain injury. Hence, the aim of the present study was to investigate the effects of uridine on ROS in the same setting. Materials and methods: Hyperoxic brain injury was induced by subjecting a total of 53 six-day-old rat pups to 80% …
Comment On: ?Treatment Of Idiopathic Granulomatous Mastitis And Factors Related Withdisease Recurrence?, Ahmet Sami̇ Akbulut, Tevfi̇k Tolga Şahi̇n
Comment On: ?Treatment Of Idiopathic Granulomatous Mastitis And Factors Related Withdisease Recurrence?, Ahmet Sami̇ Akbulut, Tevfi̇k Tolga Şahi̇n
Turkish Journal of Medical Sciences
No abstract provided.
The Role And Importance Of Auxiliary Tests In Differential Diagnosis In Patients Withmildly High Basal 17-Oh-Progesterone Levels In The Evaluation Of Hirsutism, Taner Demi̇rci̇, Hasret Cengi̇z, Ceyhun Varim, Sedat Çeti̇n
The Role And Importance Of Auxiliary Tests In Differential Diagnosis In Patients Withmildly High Basal 17-Oh-Progesterone Levels In The Evaluation Of Hirsutism, Taner Demi̇rci̇, Hasret Cengi̇z, Ceyhun Varim, Sedat Çeti̇n
Turkish Journal of Medical Sciences
Background/aim: In the differential diagnosis of hirsutism, early follicular basal 17-OH-progesterone levels sometimes overlap with the diagnosis of late onset congenital adrenal hyperplasia (LOCAH) and other causes of hyperandrogenism. This study aims to investigate the role of some common tests and clinical findings in differential diagnosis in such cases. Materials and methods: One hundred seventy-five female patients with hirsutism and mildly high initial 17-OH-progesterone levels (2-10 ng/mL) were included in the study. The cases were divided into three groups according to their diagnosis: LOCAH (n = 16, mean age = 26.1 ± 6.9), polycystic ovary syndrome (PCOS) (n = 122, …
Peripheral Axonal Excitability In Hemiplegia Related To Subacute Stroke, Zeynep Turan, Murat Zi̇nnuroğlu
Peripheral Axonal Excitability In Hemiplegia Related To Subacute Stroke, Zeynep Turan, Murat Zi̇nnuroğlu
Turkish Journal of Medical Sciences
Background/aim: This study aims to investigate peripheral nerve excitability in patients with subacute stroke. Materials and methods: The study was performed in 29 stroke patients within the subacute period and 29 healthy controls using QTRAC software and TRONDNF protocol. The threshold electrotonus, recovery cycle, stimulus-response, strength-duration, and current-threshold relationships were recorded. Results: The membrane was more hyperpolarized, and excitability was decreased in the hemiplegic side. The impairment of inward rectifying channel function, degree of hyperpolarization, and decrease of excitability were directly related to the Brunnstrom stages, which were more pronounced in lower stages. Conclusion: The lower motor neurons were affected …
The Effect Of Long-Term Systemic Immunosuppressive Drug Use On Druse Formation: A Newperspective To Age-Related Macular Degeneration, Özkan Sever, Ridvan Mercan
The Effect Of Long-Term Systemic Immunosuppressive Drug Use On Druse Formation: A Newperspective To Age-Related Macular Degeneration, Özkan Sever, Ridvan Mercan
Turkish Journal of Medical Sciences
Background/aim: To evaluate the effect of the long-term use of systemic immunosuppressive drugs on druse formation in patients aged over 50 years. Materials and methods: The current retrospective cohort study includes 420 eyes of 420 patients. 210 eyes of 210 patients who used immunosuppressive drugs (Group 1) at least for the last 5 years and 210 eyes of 210 control patients (Group 2) who did not use any drugs were compared. All patients were older than 50 years and selected among patients who were followed by rheumatology and ophthalmology clinic at a tertiary university hospital. All patients had complete ophthalmic …
Proteomic Analysis Of The Anticancer Effect Of Various Extracts Of Endemicthermopsis Turcica In Human Cervical Cancer Cells, Mustafa Yildiz, Hakan Terzi̇, Sali̇ha Handan Yildiz, Nuray Varol, Müjgan Özdemi̇r Erdoğan, Murat Kasap, Nermi̇n Akçali, Mustafa Solak
Proteomic Analysis Of The Anticancer Effect Of Various Extracts Of Endemicthermopsis Turcica In Human Cervical Cancer Cells, Mustafa Yildiz, Hakan Terzi̇, Sali̇ha Handan Yildiz, Nuray Varol, Müjgan Özdemi̇r Erdoğan, Murat Kasap, Nermi̇n Akçali, Mustafa Solak
Turkish Journal of Medical Sciences
Background/aim: Thermopsis turcica is a perennial species endemic to Turkey and different extracts of T. turcica have an antiproliferative effect on cancer cells, but there has not been any report on HeLa (human cervical cancer) cells. Materials and methods: To get a better understanding of the molecular mechanism of anticancer activity of methanolic extracts of leaves (LE) and flowers (FE) of T. turcica, we employed 2-DE-based proteomics to explore the proteins involved in anticancer activity in HeLa cells. Results: T. turcica extracts showed a potent cytotoxic effect on HeLa cells with the IC50 values of 1.75 mg/mL for LE and …
Research On The Protective Effect Of Caffeic Acid Phenethyl Ester On Testicular Damagecaused By Cisplatin, Tayfun Ceylan, Emi̇n Kaymak, Fazi̇le Cantürk Tan, Bi̇rkan Yakan
Research On The Protective Effect Of Caffeic Acid Phenethyl Ester On Testicular Damagecaused By Cisplatin, Tayfun Ceylan, Emi̇n Kaymak, Fazi̇le Cantürk Tan, Bi̇rkan Yakan
Turkish Journal of Medical Sciences
Background/aim: Cisplatin (CP), a chemotherapeutic drug, causes damage to spermatogenic serial cells, Sertoli cells, and Leydig cells in rat testicles. It was aimed to investigate the protective effect of caffeic acid phenethyl ester (CAPE), one of the active ingredients of propolis, in eliminating CP-induced testicular damage. Materials and methods: Group 1 (control group) was given physiological saline solution intraperitoneally (IP) throughout the experiment. Group 2 (CP group) was given a single dose of CP (7 mg/kg) IP on the day 7. Group 3 (CP + CAPE group), was given CAPE (10 μmol/kg/day) IP for 12 days and a single dose …
Comparison Of The Sensititre Yeastone Antifungal Method With The Clsi M27-A3reference Method To Determine The Activity Of Antifungal Agents Against Clinical Isolatesof Candida Spp., Rabi̇ye Altinbaş, Ayşe Bariş, Sümeyye Şen, Recep Öztürk, Nuri̇ Ki̇raz
Comparison Of The Sensititre Yeastone Antifungal Method With The Clsi M27-A3reference Method To Determine The Activity Of Antifungal Agents Against Clinical Isolatesof Candida Spp., Rabi̇ye Altinbaş, Ayşe Bariş, Sümeyye Şen, Recep Öztürk, Nuri̇ Ki̇raz
Turkish Journal of Medical Sciences
Background and aim: Infections caused by Candida species are significantly increasing today, and invasive Candida infections are generally associated with high mortality. Early diagnosis and identification of Candida spp. is important for the determination of antifungal agents that will be used for treatment. The aim of the present study was to provide a better regimen for Candida infections in the future. Materials and methods: The Sensititre YeastOne (SYO) method was compared with The Clinical Laboratory Standards Institute (CLSI) reference broth microdilution (BMD) testing method. Endpoints of minimal inhibitory concentrations (MICs) were determined for both methods. Results: By using both methods, …
In Reply: Comparing Performance Of Mcgrath Mac Videolaryngoscope In Morbidlyobese And Nonobese, Zehra İpek Arslan Aydin
In Reply: Comparing Performance Of Mcgrath Mac Videolaryngoscope In Morbidlyobese And Nonobese, Zehra İpek Arslan Aydin
Turkish Journal of Medical Sciences
No abstract provided.
Mango Ginger (Curcuma Amada) Inhibits Collagen-Induced Arthritis By Modulatinginflammatory Cytokine Levels In Rats, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Nurhan Şahi̇n, İbrahi̇m Hani̇fi̇ Özercan, Süleyman Serdar Koca, Vijaya Juturu, Kazi̇m Şahi̇n
Mango Ginger (Curcuma Amada) Inhibits Collagen-Induced Arthritis By Modulatinginflammatory Cytokine Levels In Rats, Ahmet Karataş, Cemal Orhan, Mehmet Tuzcu, Nurhan Şahi̇n, İbrahi̇m Hani̇fi̇ Özercan, Süleyman Serdar Koca, Vijaya Juturu, Kazi̇m Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: Mango ginger (MG: curcuma amada) has antioxidant and antiinflammatory activities. The aim was to evaluate the antiarthritic potential efficacy of MG on collagen-induced arthritis. Materials and methods: Twenty-one female Wistar-albino rats were divided into three groups. Arthritis was induced by intradermal injections of type II collagen and Freund's adjuvant. MG extract was orally administered starting from the first collagen injection. TNF-α, IL-6, IL-17, obestatin, sclerostin, and DKK-1 serum levels were determined, and perisynovial inflammation and cartilage-bone destruction in the paws were histologically evaluated. Moreover, joint tissue TNF-α, IL-17, NF-κB, and COX-2 levels were analyzed. Results: TNF-α, IL-17, IL-6, and …
Comment On `Treatment Of Idiopathic Granulomatous Mastitis And Factors Related Withdisease Recurrence?, Emre Tekgöz, Seda Çolak, Muhammet Çinar, Sedat Yilmaz
Comment On `Treatment Of Idiopathic Granulomatous Mastitis And Factors Related Withdisease Recurrence?, Emre Tekgöz, Seda Çolak, Muhammet Çinar, Sedat Yilmaz
Turkish Journal of Medical Sciences
No abstract provided.
Preemptive Action Saves Lives In A Pandemic: Closing The Grand Bazaar Before Thecovid-19 Infection Starts, Abdullah Emre Güner, Kemal Memi̇şoğlu, Şuayip Bi̇ri̇nci̇
Preemptive Action Saves Lives In A Pandemic: Closing The Grand Bazaar Before Thecovid-19 Infection Starts, Abdullah Emre Güner, Kemal Memi̇şoğlu, Şuayip Bi̇ri̇nci̇
Turkish Journal of Medical Sciences
No abstract provided.
Mobilizing The Research Ecosystem For Scientific Advances Towards Positive Impact In Thecontext Of The Covid-19 Pandemic, Hasan Mandal
Mobilizing The Research Ecosystem For Scientific Advances Towards Positive Impact In Thecontext Of The Covid-19 Pandemic, Hasan Mandal
Turkish Journal of Medical Sciences
This special issue of the Turkish Journal of Medical Sciences is dedicated to providing scientific advances in the process of better understanding the SARS-CoV-2 virus that causes the COVID-19 infection. The special issue is published in a special time in which science-based approaches, cocreation-based collaboration, and the effective utilization and integration of competences have a crucial role during the race against time while combating the COVID-19 pandemic. In this process, the Scientific and Technological Research Council of Turkey (TÜBİTAK), which publishes academic journals including the Turkish Journal of Medical Sciences, has taken rapid action to mobilize the research community. This …
Global Threat Of Covid 19 And Evacuation Of The Citizens Of Different Countries, İrfan Şencan, Semanur Kuzi̇
Global Threat Of Covid 19 And Evacuation Of The Citizens Of Different Countries, İrfan Şencan, Semanur Kuzi̇
Turkish Journal of Medical Sciences
Beginning from China on December 2019, COVID-19 epidemic has spreaded all over the world in a short period of time and has been a pandemic. In challenge with this pandemic quarantine technique has been used widely after tens of years. In the course of the pandemic, many countries evacuated their citizens from affected regions and combined the evacuation with quarantine process. Some examples of these countries who evacuated their citizens are Germany, Italy, Spain, and USA. In further times, during the course of pandemic, according to spread, other countries evacuated their citizens from these countries too. Despite being the origin …
Covid-19 Outbreak Control, Example Of Ministry Of Health Of Turkey, Yasemi̇n Demi̇rbi̇lek, Gülen Pehli̇vantürk, Zeynep Özge Özgüler, Emi̇ne Alp Meşe
Covid-19 Outbreak Control, Example Of Ministry Of Health Of Turkey, Yasemi̇n Demi̇rbi̇lek, Gülen Pehli̇vantürk, Zeynep Özge Özgüler, Emi̇ne Alp Meşe
Turkish Journal of Medical Sciences
Our first COVID-19 case in Turkey was a 44-year-old male who referred to the hospital on March 9, 2020. The first related death occurred on March 17, 2020. Preparedness for the pandemic has been ongoing before the first case was detected. The National Pandemic Plan was published in 2006. The Pandemic Influenza National Preparedness Plan was available after being updated in light of experiences gained during the 2009 Influenza A pandemic. Accordingly, Pandemic Coordination Boards and Operation Centers have been established on the national and provincial levels. This was an adaptable plan to the Novel Coronavirus Disease (COVID-19). We formed …
Protective Measures For Covid-19 For Healthcare Providers And Laboratory Personnel, Canan Ağalar, Derya Öztürk Engi̇n
Protective Measures For Covid-19 For Healthcare Providers And Laboratory Personnel, Canan Ağalar, Derya Öztürk Engi̇n
Turkish Journal of Medical Sciences
In the COVID-19 pandemic, which affects the whole world, healthcare professionals (HCP) are at high risk of transmission due to their direct contact with patients with COVID-19. Therefore, how to ensure the triage of the patient with acute respiratory symptoms should be determined in advance, the contact distance should be arranged to be at least 2 m, COVID-19 suspect or diagnosed patient should be instructed to wear a surgical mask. During the care of these patients, HCP should wear their personal protective equipment (PPE) in accordance with the procedure and should not neglect hand hygiene. The samples of the patient …