Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- COVID-19 (110)
- Children (97)
- Oxidative stress (90)
- Inflammation (65)
- Rat (62)
-
- Mortality (59)
- Treatment (57)
- Turkey (57)
- Breast cancer (51)
- Prognosis (51)
- Pregnancy (49)
- Apoptosis (47)
- Prevalence (47)
- Magnetic resonance imaging (46)
- Obesity (46)
- Diabetes mellitus (37)
- Quality of life (36)
- Risk factors (36)
- Diagnosis (34)
- Nitric oxide (32)
- Ultrasonography (32)
- Rheumatoid arthritis (31)
- Epidemiology (30)
- Asthma (29)
- Hypertension (29)
- Reliability (29)
- Child (28)
- Validity (28)
- Depression (26)
- Diabetes (26)
- Publication Year
Articles 1381 - 1410 of 4871
Full-Text Articles in Medicine and Health Sciences
Effects Of Different Analgesic Methods Used For Vaginal Delivery On Mothers And Fetuses, Gülçi̇n Babaoğlu, Banu Kiliçaslan, Aysun Ankay Yilbaş, Bi̇lge Çelebi̇oğlu
Effects Of Different Analgesic Methods Used For Vaginal Delivery On Mothers And Fetuses, Gülçi̇n Babaoğlu, Banu Kiliçaslan, Aysun Ankay Yilbaş, Bi̇lge Çelebi̇oğlu
Turkish Journal of Medical Sciences
Background/aim: Knowledge regarding pain relief during labor remains insufficient. We aimed to determine and compare the effectiveness and safety of epidural analgesia, combined spinal-epidural analgesia, and parenteral meperidine on both mothers and fetuses. Materials and methods: This study was designed as an observational case-control study. We collected prospective data from patients whose labor pain management was conducted with meperidine in addition to retrospective cohort data of neuraxial methods; 138 patients were enrolled. Epidural analgesia group consisted of 68 patients, whereas combined spinal-epidural (CSE) analgesia group and meperidine group consisted of 50 and 20 patients, respectively. We compared the delivery patterns, …
The Profitmap-Neck - A Questionnaire For Measuring Symptoms And Functional Limitations In Neck Pain: Reliability, Validity And Cross-Cultural Adaptation Of The Turkish Version, Hati̇ce Çeti̇n, Nezi̇re Köse, Sevi̇l Bi̇lgi̇n, Haluk Tekerlek, Esra Dülger, Ceyhun Türkmen, Jale Karakaya
The Profitmap-Neck - A Questionnaire For Measuring Symptoms And Functional Limitations In Neck Pain: Reliability, Validity And Cross-Cultural Adaptation Of The Turkish Version, Hati̇ce Çeti̇n, Nezi̇re Köse, Sevi̇l Bi̇lgi̇n, Haluk Tekerlek, Esra Dülger, Ceyhun Türkmen, Jale Karakaya
Turkish Journal of Medical Sciences
Background/aim: The Profile Fitness Mapping neck questionnaire (ProFitMap-neck) is a reliable and valid assessment instrument for measuring neck-related symptoms and functional limitations in people with neck pain, but a Turkish version of it had not been published. The purpose of this study was to investigate the adaptation, validity, and intrarater reliability of the Turkish version of the ProFitMap-neck. Materials and methods: Two hundred and thirty-five individuals with chronic neck pain were enrolled in the study. Intrarater reliability was assessed by intraclass correlation coefficient (ICC) and Cronbach's alpha was calculated for internal consistency. For concurrent validity, ProFitMap-neck scores were compared with …
Factors Associated With Severe Lung Disease In An Adult Population With Cystic Fibrosis: A Single-Center Experience, Berri̇n Er, Ebru Çelebi̇oğlu, Ebru Yalçin, Deni̇z Doğru, Özlem Erden Aki̇, Ömrüm Uzun, Murat Akova, Uğur Özçeli̇k, Nural Ki̇per, Sali̇h Emri̇
Factors Associated With Severe Lung Disease In An Adult Population With Cystic Fibrosis: A Single-Center Experience, Berri̇n Er, Ebru Çelebi̇oğlu, Ebru Yalçin, Deni̇z Doğru, Özlem Erden Aki̇, Ömrüm Uzun, Murat Akova, Uğur Özçeli̇k, Nural Ki̇per, Sali̇h Emri̇
Turkish Journal of Medical Sciences
Background/Aim: The patients with cystic fibrosis (CF) are living longer compared to the past, but respiratory failure is still the most common cause of mortality. The aim of this study is to investigate factors associated with severe lung disease in a cohort of adult patients with CF. Materials and methods: Demographic data, clinical and laboratory findings of the patients aged 18 years and more were collected and the patients were grouped according to forced expiratory volume in 1 s (FEV1) as severe group:
Validating The Turkish Version Of The Weinstein Noise Sensitivity Scale: Effects Of Age, Sex, And Education Level, Meli̇s Keski̇n Yildiz, Yusuf Kemal Kemaloğlu, Yetki̇n Tuaç, Güven Mengü, Recep Karamert, Çağil Gökdoğan
Validating The Turkish Version Of The Weinstein Noise Sensitivity Scale: Effects Of Age, Sex, And Education Level, Meli̇s Keski̇n Yildiz, Yusuf Kemal Kemaloğlu, Yetki̇n Tuaç, Güven Mengü, Recep Karamert, Çağil Gökdoğan
Turkish Journal of Medical Sciences
Background/aim: Subjective noise sensitivity (SNS) is not only one of the most important predictors of perceived noise annoyance for the subjects exposed to the noise, but also strongly related with some psychological conditions and poor health perception of the subjects. Weinstein's Noise Sensitivity Scale (WNSS) is widely used for measuring of SNS. Materials and methods: In this study we adapted WNSS to Turkish (Tr-WNSS) and evaluated its psychometric properties and effect of age, sex and education level on SNS. Results: The study included 105 males and 105 female subjects between 18 and 55 years of age. Conclusion: Our data demonstrated …
Risk Indices That Predict In-Hospital Mortality Of Elderly Patients, Di̇lek Dülger, Özgür Albuz
Risk Indices That Predict In-Hospital Mortality Of Elderly Patients, Di̇lek Dülger, Özgür Albuz
Turkish Journal of Medical Sciences
Background/aim: Mortality in the elderly population tends to be higher than in all other age groups; the risk factors that predict mortality among those in this age cohort are not fully understood. This large-scale clinical study aimed to identify effective risk factors that predict mortality in the elderly population with a particular focus on age and hospitalization status. Material and methods: We retrospectively analyzed outcomes from patients with clinical follow-up between July 2015 and January 2020 at 29 Mayıs State Hospital, Ankara, Turkey. Patient records with missing or ambiguous data were excluded. Age, sex, length of hospital stay, comorbidities, consultation …
The Effect Of Sacrospinous Ligament Fixation During Vaginal Hysterectomy On Postoperative De Novo Stress Incontinence Occurrence: A Prospective Study With 2-Year Follow-Up, Eralp Başer, Kerem Doğa Seçki̇n, Pinar Kadi̇roğullari, Hüseyi̇n Kiyak
The Effect Of Sacrospinous Ligament Fixation During Vaginal Hysterectomy On Postoperative De Novo Stress Incontinence Occurrence: A Prospective Study With 2-Year Follow-Up, Eralp Başer, Kerem Doğa Seçki̇n, Pinar Kadi̇roğullari, Hüseyi̇n Kiyak
Turkish Journal of Medical Sciences
Background/aim: To investigate the risk of de novo stress urinary incontinence (SUI) occurrence in women who were treated for pelvic organ prolapse (POP) with sacrospinous ligament fixation (SSLF) in addition to vaginal hysterectomy (VAH) and antero-posterior colporrhaphy (CAP) over a 24-month follow-up period. Materials and methods: A prospective randomized study was designed. Women without occult or obvious SUI were randomized into either one of the study groups: Group 1: VAH + CAP, and Group 2: VAH + CAP + SSLF. Postoperatively, the patients were reevaluated for de novo SUI occurrence. Results: A total of 150 women were analyzed [G1 = …
Evaluation Of The Effects Of Ss1-Selective Beta-Blockers On Bone Mineral Density And Fracture Risk In Postmenopausal Women, Betül Yavuz Keleş, Meltem Vural, Burcu Önder, Kadri̇ye Öneş
Evaluation Of The Effects Of Ss1-Selective Beta-Blockers On Bone Mineral Density And Fracture Risk In Postmenopausal Women, Betül Yavuz Keleş, Meltem Vural, Burcu Önder, Kadri̇ye Öneş
Turkish Journal of Medical Sciences
Background/aim: ß1-selective beta-blockers (BBs) are sympatholytic agents, and discerning their effects on bone health would be of great importance. This study aimed to investigate the influence of ß1-selective BBs on bone mineral density (BMD) and fracture risk. Materials and methods: This study included postmenopausal women who used ß1-selective BBs (BB group) and control group. Sociodemographic characteristics, BMD and previous fragility fractures were recorded. Additionally, the 10-year probability of a major osteoporotic and hip fracture was calculated using the fracture risk assessment tool (FRAX). Results: A total of 60 participants were included in the study. L1-4 and L2-4 BMD values were …
Evaluation Of The Cardioprotective Effects Of Crystalloid Del Nido Cardioplegia Solution Via A Rapid And Accurate Cardiac Marker: Heart-Type Fatty Acid-Binding Protein, Mehmet Ki̇ri̇şci̇, Aydemi̇r Koçarslan, Duygun Altintaş Aykan, Fi̇li̇z Alkan Baylan, Adem Doğaner, Yavuz Orak
Evaluation Of The Cardioprotective Effects Of Crystalloid Del Nido Cardioplegia Solution Via A Rapid And Accurate Cardiac Marker: Heart-Type Fatty Acid-Binding Protein, Mehmet Ki̇ri̇şci̇, Aydemi̇r Koçarslan, Duygun Altintaş Aykan, Fi̇li̇z Alkan Baylan, Adem Doğaner, Yavuz Orak
Turkish Journal of Medical Sciences
Background/aim: Our aim in this study was to compare the efficacy and safety of crystalloid del Nido solution and cold blood cardioplegia solution on clinical and laboratory parameters. Materials and methods: Sixty patients who underwent elective coronary bypass operation between July 2019 and January 2020 were included in our study. Patients were divided into 2 groups of 30 patients using del Nido solution (DNS) and cold blood cardioplegia solution (CBCS), which were given for cardiac arrest. Demographic data, preoperative, postoperative 0th h, 6th h and 4th day creatine kinase myocardial band (CK-MB) and troponin I values were compared with a …
Spectrum Of Germline Cancer Susceptibility Gene Mutations In Turkish Colorectal Cancer Patients: A Single Center Study, Haktan Bağiş Erdem, Taha Bahsi̇
Spectrum Of Germline Cancer Susceptibility Gene Mutations In Turkish Colorectal Cancer Patients: A Single Center Study, Haktan Bağiş Erdem, Taha Bahsi̇
Turkish Journal of Medical Sciences
Background/aim: Quarter of colorectal cancer patients have a family history and 6% of these comprise hereditary cancer syndromes. For developing national health strategies for genetic screening, it is crucial to determine the spectrum of damaging alterations in causative genes and to describe frequent founder mutations. Materials and methods: One hundred and thirty six unrelated colorectal cancer cases were investigated. Qiagen large hereditary cancer panel and Hereditary Cancer Solution v1.1 panel were used for sequencing. The sequencing process was performed on the Illumina MiSeq system. The data analyses were performed on QIAGEN Clinical Insight (QCITM) Analyze software and Sophia DDM software. …
The Relationship Of The Immune Response Mediator Genes' Polymorphic Variants With The Methotrexate Efficacy In Juvenile Idiopathic Arthritis, Liliia Nazarova, Ksenia Danilko, Viktor Malievsky, Denis Karimov, Akhat Bakirov, Tatiana Viktorova
The Relationship Of The Immune Response Mediator Genes' Polymorphic Variants With The Methotrexate Efficacy In Juvenile Idiopathic Arthritis, Liliia Nazarova, Ksenia Danilko, Viktor Malievsky, Denis Karimov, Akhat Bakirov, Tatiana Viktorova
Turkish Journal of Medical Sciences
Background/aim: The aim of the study was to analyze the relationship of the immune response mediator genes' polymorphic loci (TNFA rs1800629, LTA rs909253, IL1B rs16944, IL2-IL21 rs6822844, IL2RA rs2104286, IL6 rs1800795, IL10 rs1800872, MIF rs755622, CTLA4 rs3087243, NFKB1 rs28362491, PTPN22 rs2476601, PADI4 rs2240336) variants with the methotrexate efficacy in juvenile idiopathic arthritis (JIA). Materials and methods: The study included 274 JIA patients from the Republic of Bashkortostan, Russia. Achieving the American College of Rheumatology Pediatric 30 (ACR Pedi 30) response was regarded as the presence of the response to methotrexate (otherwise, as the absence), while achieving clinical remission on medication …
Optimization Of Isothermal Amplification Method For Mycobacterium Tuberculosis Detection And Visualization Method For Fieldwork, Hati̇ce Esra Ağel, Hasan Sağcan, İsmai̇l Ceyhan, Riza Durmaz
Optimization Of Isothermal Amplification Method For Mycobacterium Tuberculosis Detection And Visualization Method For Fieldwork, Hati̇ce Esra Ağel, Hasan Sağcan, İsmai̇l Ceyhan, Riza Durmaz
Turkish Journal of Medical Sciences
Background/aim: Tuberculosis is still one of the most contagious diseases around the world. Key factors of tuberculosis control are rapid diagnostic, efficient treatment, and prevention of contamination by surveillance and monitoring. However, culture is the gold standard method for laboratory diagnosis of tuberculosis; the results are several weeks to obtain. In order to prevent contamination of tuberculosis, diagnosis must be made in short time and treatment should be started as soon as possible. The aim of this study is to optimize the loop-mediated isothermal amplification (LAMP) method, which provides a much faster and more sensitive result than the polymerase chain …
Does Capsaicin Have Therapeutic Benefits In Human Colon Adenocarcinoma? Selection Of The Most Reliable Dose Via Agnor, Mustafa Ni̇sari̇, Recep Eröz
Does Capsaicin Have Therapeutic Benefits In Human Colon Adenocarcinoma? Selection Of The Most Reliable Dose Via Agnor, Mustafa Ni̇sari̇, Recep Eröz
Turkish Journal of Medical Sciences
Background/aim: To determine the effect of different doses of capsaicin on AgNOR protein synthesis in human colon adenocarcinoma derivate from colon cancer (Caco-2 cell). Materials and methods: In this experimental study, after the cultured of Caco-2 cell line, the cells are divided into 4 groups as control and different capsaicin exposed doses (25uµ, 50uµ, and 75uµ). Mean AgNOR number and total AgNOR area/nuclear area (TAA/NA) were calculated. Results: A significant differences were detected between control and capsaicin (50uµ) (P = 0.001), between control and capsaicin (75uµ) (P = 0.000), between capsaicin (25uµ) and capsaicin (50uµ) (P = 0.001) and between …
The Effect Of Rituximab On Encapsulated Peritoneal Sclerosis In An Experimental Rat Model, Süleyman Karaköse, Ayşe Zeynep Bal, Eylem Pinar Eser, Murat Duranay
The Effect Of Rituximab On Encapsulated Peritoneal Sclerosis In An Experimental Rat Model, Süleyman Karaköse, Ayşe Zeynep Bal, Eylem Pinar Eser, Murat Duranay
Turkish Journal of Medical Sciences
Background/aim: Peritoneal sclerosis may be observed in varied manifestations. However, the most serious form is the encapsulated peritoneal sclerosis. We researched the effect of rituximab on peritoneal fibrosis in an experimental rat model. Materials and methods: Twenty-four Wistar Albino rats were divided into 4 equal groups. During weeks 0-3; group I received isotonic saline (IS) solution, group II, group III, and group IV received chlorhexidine gluconate (CG) via intraperitoneal (i.p.) route. In the next 3 weeks nothing adminestred to both group I and group II but IS solution was adminestred to group III via i.p. route and 375 mg/m2/ week …
Analysing The Blood-Stemming Effect Of Ankaferd Blood Stopper In Medulla Spinalis Surgery, Dursun Turkoz, Cem Demi̇rel, Hüseyi̇n Sataloğlu, Cengiz Cokluk
Analysing The Blood-Stemming Effect Of Ankaferd Blood Stopper In Medulla Spinalis Surgery, Dursun Turkoz, Cem Demi̇rel, Hüseyi̇n Sataloğlu, Cengiz Cokluk
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the possible toxicity of the Ankaferd Blood Stopper (ABS) on the neural system. Materials and methods: Thirty Sprague Dawley rats were randomized into ABS (n: 15) and control (n: 15) groups. Following the anaesthetic induction, total laminectomy was performed to the lower thoracic, and upper lumbar areas in both groups and medulla spinalis was exposed. Two myelotomies were performed on the medulla spinalis. One millilitre ABS was applied to the incision site in the ABS group, and one millilitre 0.9% saline solution was applied in the control group. Rats were observed …
Reply To Letter To The Editor, Zehra İpek Arslan Aydin
Reply To Letter To The Editor, Zehra İpek Arslan Aydin
Turkish Journal of Medical Sciences
No abstract provided.
Immunomagnetic Separation And Listeria Monocytogenes Detection With Surface- Enhanced Raman Scattering, Hande Yeğenoğlu Akçinar, Belma Aslim, Hi̇lal Torul, Burcu Güven, Adem Zengi̇n, Zeki̇ye Suludere, İsmai̇l Hakki Boyaci, Uğur Tamer
Immunomagnetic Separation And Listeria Monocytogenes Detection With Surface- Enhanced Raman Scattering, Hande Yeğenoğlu Akçinar, Belma Aslim, Hi̇lal Torul, Burcu Güven, Adem Zengi̇n, Zeki̇ye Suludere, İsmai̇l Hakki Boyaci, Uğur Tamer
Turkish Journal of Medical Sciences
Background/aim: We aimed to develop a rapid method to enumerate Listeria monocytogenes (L. monocytogenes) utilizing magnetic nanoparticle based preconcentration and surface-enhanced Raman spectroscopy measurements. Materials and methods: Biological activities of magnetic Au-nanoparticles have been observed to have the high biocompatibility, and a sample immunosensor model has been designed to use avidin attached Au-nanoparticles for L. monocytogenes detection. Staphylococcus aureus (S. aureus) and Salmonella typhimurium (S. typhimurium) bacteria cultures were chosen for control studies. Antimicrobial activity studies have been done to identify bio-compatibility and bio-characterization of the Au-nanoparticles in our previous study and capturing efficiencies to bacterial surfaces have been also …
Nanotoxicity: A Challenge For Future Medicine, Ramazan Akçan, Hali̇t Canberk Aydogan, Mahmut Şeri̇f Yildirim, Burak Taşteki̇n, Necdet Sağlam
Nanotoxicity: A Challenge For Future Medicine, Ramazan Akçan, Hali̇t Canberk Aydogan, Mahmut Şeri̇f Yildirim, Burak Taşteki̇n, Necdet Sağlam
Turkish Journal of Medical Sciences
Background/aim: Due to nanomaterials' potential benefits for diagnosis and treatment, they are widely used in medical applications and personal care products. Interaction of nanomaterials, which are very small in size, with tissue, cell and microenvironment, can reveal harmful effects that cannot be created with chemically identical and larger counterparts in biological organisms. In this review, a challenge for future medicine, nanotoxicity of nanomaterials is discussed. Materials and methods: A detailed review of related literature was performed and evaluated as per medical applications of nanomaterials their toxicity. Results and conclusion: Most authors state "the only valid technology will be nanotechnology in …
Neuroprotective Effects Of Quercetin On Cerebral Vasospasm Following Experimental Subarachnoid Haemorrhage In Rats, Şanser Gül, Evren Aydoğmuş, Burak Bahadir, Mustafa Çağatay Büyükuysal, Berrak Güven
Neuroprotective Effects Of Quercetin On Cerebral Vasospasm Following Experimental Subarachnoid Haemorrhage In Rats, Şanser Gül, Evren Aydoğmuş, Burak Bahadir, Mustafa Çağatay Büyükuysal, Berrak Güven
Turkish Journal of Medical Sciences
Background/aim: We examined the protective effects of the natural flavonoid, quercetin, against cerebral vasospasm in an experimental rat subarachnoid haemorrhage (SAH) model. Materials and methods: Thirty-eight albino Wistar rats were divided into five groups as follows: group 1 (G1, n=8), no experimental intervention; group 2 (G2, n=8), subarachnoid physiological saline; group 3 (G3, n=8), SAH; group 4 (G4, n=7) SAH and low-dose (10 mg/kg) quercetin treatment; group 5 (G5, n=7), SAH and high-dose (50 mg/kg) quercetin treatment. Subarachnoid haemorrhage was induced by injection of 0.15 cc of autologous blood taken from the tail artery into the cisterna magna from the …
Could Hif-1∝ Be A Novel Biomarker For The Clinical Course And Treatment Of Pulmonary Embolism?, Buğra Kerget, Dursun Erol Afşi̇n, Alperen Aksakal, Alperen Aksakal, Seda Aşkin, Ömer Araz
Could Hif-1∝ Be A Novel Biomarker For The Clinical Course And Treatment Of Pulmonary Embolism?, Buğra Kerget, Dursun Erol Afşi̇n, Alperen Aksakal, Alperen Aksakal, Seda Aşkin, Ömer Araz
Turkish Journal of Medical Sciences
Background/aim: Pulmonary embolism (PE) is associated with high morbidity and mortality rates if not diagnosed and treated rapidly. The aim of our study was to investigate the relationship between levels of hypoxia-induced factor-1 alpha (HIF-1∝) and clinical course and prognosis in patients with intermediate low-risk, intermediate high-risk, and high-risk PE. Materials and methods: The study included 240 subjects in 4 groups: a healthy control group (n = 60, mean age = 60 ± 15.2, female/male = 30/30 ), intermediate low-risk PE group (n = 60, mean age = 60 ± 12,5, female/male = 27/33), intermediate high-risk PE group (n = …
Ocular Toxicity Of Intravitreal Golimumab In A Rabbit Model, Ceren Durmaz Engi̇n, Serap Ci̇laker Miçili, Osman Yilmaz, Hüsnü Alper Bağriyanik, Beki̇r Uğur Ergür, Fatoş Önen, Ali̇ Osman Saatci̇
Ocular Toxicity Of Intravitreal Golimumab In A Rabbit Model, Ceren Durmaz Engi̇n, Serap Ci̇laker Miçili, Osman Yilmaz, Hüsnü Alper Bağriyanik, Beki̇r Uğur Ergür, Fatoş Önen, Ali̇ Osman Saatci̇
Turkish Journal of Medical Sciences
Background/aim: To investigate the effect of intravitreal golimumab on rabbit retina histopathology. Materials and methods: Sixteen albino New Zealand rabbits were divided into three groups. The right eye of each rabbit in groups I, II, and III received a single intravitreal injection of 5 mg/0.05 mL (6 eyes), 10 mg/0.1 mL (6 eyes), or 20 mg/0.2 mL (4 eyes) golimumab, while left eyes served as controls with the same volume of a balanced salt solution injection. All animals were examined using slit-lamp biomicroscopy and indirect ophthalmoscopy before and after intravitreal injection and at days 1 and 7. Animals were euthanized …
Comment On: "Which Nostril Should Be Used For Nasotracheal Intubation With Airtraq Nt®: The Right Or Left?", Raghuraman M. Sethuraman
Comment On: "Which Nostril Should Be Used For Nasotracheal Intubation With Airtraq Nt®: The Right Or Left?", Raghuraman M. Sethuraman
Turkish Journal of Medical Sciences
No abstract provided.
Comparison Of Mesenchymal Stem Cell Sheets And Chondrocyte Sheets In A Rabbit Growth Plate Injury Model, Alper Gülteki̇n, Yücel Ağirdi̇l, Büşra Öncel Duman, Cansu Subaşi, Erdal Karaöz
Comparison Of Mesenchymal Stem Cell Sheets And Chondrocyte Sheets In A Rabbit Growth Plate Injury Model, Alper Gülteki̇n, Yücel Ağirdi̇l, Büşra Öncel Duman, Cansu Subaşi, Erdal Karaöz
Turkish Journal of Medical Sciences
Background/aim: The treatment of posttraumatic deformities and differences in length between the extremities resulting from physeal injury remains controversial. The aims of this study were to compare the efficacy of tissue-engineered, monolayer, and allogeneic mesenchymal stem cell sheets and chondrocyte sheets for physeal arrest treatment and to investigate cell sheet technology as a novel method for cell transplantation in physeal cartilage repair. Materials and methods: A proximal tibial physeal injury was induced in New Zealand rabbits. Allogeneic mesenchymal stem cells (MSCs) and chondrocytes were cultured in temperature-responsive culture dishes and applied to the iatrogenic partial growth plate defects in single-sheet …
Importance Of The National Early Warning Score (News) At The Time Of Discharge From The Intensive Care Unit, Ci̇hangi̇r Doğu, Güvenç Doğan, Selçuk Kayir, Özgür Yağan
Importance Of The National Early Warning Score (News) At The Time Of Discharge From The Intensive Care Unit, Ci̇hangi̇r Doğu, Güvenç Doğan, Selçuk Kayir, Özgür Yağan
Turkish Journal of Medical Sciences
Backround/aim: To identify, at an early stage of intensive care, patients who will require readmission to the intensive care unit (ICU) based on their National Early Warning Score (NEWS-d) at discharge.Materials and methods: Overall, 536 patients aged >18 years who stayed at a tertiary ICU for >24 h were included. Patients who readmitted and not readmitted to the intensive care within 48 h after discharge were compared.Results: Mean patient age was 64.26 ± 18.50 years and 252 (44.7%) patients were male. Mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score was 21.86 ± 8.74; mean NEWS-d was 4.48 …
Value Of Prognostic Scores In Antineutrophil Cytoplasmic Antibody (Anca) Associated Vasculitis Patients In Intensive Care Unit: A Multicenter Retrospective Cohort Study From Turkey, Uğur Özdemi̇r, Nazmi̇ye Ebru Ortaç Ersoy, Recep Ci̇van Yüksel, Erhan Kaya, Şahender Gülbi̇n Aygencel Bikmaz, Melda Türkoğlu, Arzu Topeli̇ İski̇t, Muhammet Güven, Murat Sungur, Neri̇man Defne Altintaş
Value Of Prognostic Scores In Antineutrophil Cytoplasmic Antibody (Anca) Associated Vasculitis Patients In Intensive Care Unit: A Multicenter Retrospective Cohort Study From Turkey, Uğur Özdemi̇r, Nazmi̇ye Ebru Ortaç Ersoy, Recep Ci̇van Yüksel, Erhan Kaya, Şahender Gülbi̇n Aygencel Bikmaz, Melda Türkoğlu, Arzu Topeli̇ İski̇t, Muhammet Güven, Murat Sungur, Neri̇man Defne Altintaş
Turkish Journal of Medical Sciences
Background/aim: There is a need for a scoring system for predicting ICU prognosis of patients with ANCA-associated vasculitis (AAV), but there are limited data on it in the literature. Therefore, we aimed to determine the scores that can estimate the prognosis of patients with AAV during intensive care follow up.Materials and methods: All adult patients admitted to the medical ICUs of 4 reference university hospitals in Turkey due to AAV activation and/or disease/treatment complications in the last 10 years were included in this study. Demographic data, treatments before ICU, the Birmingham Vasculitis Activity Score (BVAS) score at the time of …
Surgical Management Of Insulinomas At The Azerbaijan Medical University: A Retrospective Study Of 21 Cases Over A 10-Year Period, Rovshan Hasanov, Elgun Samadov, Nuru Bayramov, Ayteki̇n Ünlü, Patrizio Petrone
Surgical Management Of Insulinomas At The Azerbaijan Medical University: A Retrospective Study Of 21 Cases Over A 10-Year Period, Rovshan Hasanov, Elgun Samadov, Nuru Bayramov, Ayteki̇n Ünlü, Patrizio Petrone
Turkish Journal of Medical Sciences
Background/aim: This study represents the first report that evaluates the experience gathered from diagnosis, surgical treatment and outcome of insulinoma patients from Azerbaijan.Materials and methods: We retrospectively review of insulinoma patients for a 10-year period. Collected data included patient demographics, laboratory and imaging tests, detailed surgical reports, histopathological examination of resected specimens, and clinical follow-up.Results: Twenty-one insulinoma patients were identified. Male patients comprised 52.4%; mean age was 44 years. Mean time to diagnosis was 14 months; 61% patients had ≥3 medical referrals due to hypoglycemia-related symptoms. Diagnosis sensitivity of CT, MRI and US was 85%, 80%, and 55%, respectively. The …
Noninvasive Monitoring Of Central Venous Oxygen Saturation By Jugular Transcutaneous Near-Infrared Spectroscopy In Pediatric Patients Undergoing Congenital Cardiac Surgery, Di̇lek Altun, Abdullah Doğan, Ahmet Arnaz, Adnan Yüksek, Yusuf Kenan Yalçinbaş, Riza Türköz, Cafer Tayyar Sarioğlu
Noninvasive Monitoring Of Central Venous Oxygen Saturation By Jugular Transcutaneous Near-Infrared Spectroscopy In Pediatric Patients Undergoing Congenital Cardiac Surgery, Di̇lek Altun, Abdullah Doğan, Ahmet Arnaz, Adnan Yüksek, Yusuf Kenan Yalçinbaş, Riza Türköz, Cafer Tayyar Sarioğlu
Turkish Journal of Medical Sciences
Background and aim: In patients undergoing congenital cardiac surgery, it is crucial to maintain oxygen demand-consumption balance. Central venous oxygen saturation (ScvO2) is a useful indicator of oxygen demand and consumption balance which is an invasive method. Near-infrared spectroscopy (NIRS) is a noninvasive, continuous monitoring technique that measures regional tissue oxygenation. NIRS that is placed over the internal jugular vein cutaneous area (NIRSijv) has the potential to show ScvO2 indirectly. In this study, we aimed to determine the correlation between ScvO2 with NIRSijv in pediatric patients undergoing congenital cardiac surgery.Materials and methods: Fifty children participated in the study. Four patients …
The Association Between Temperament Features And Childhood Traumas In Patients With Juvenile Myoclonic Epilepsy, Ali̇şan Burak Yaşar, Ceyhun Sayman, Serap Erdoğan Taycan, Yilmaz Çeti̇nkaya, Anil Gündüz, Hülya Ti̇reli̇
The Association Between Temperament Features And Childhood Traumas In Patients With Juvenile Myoclonic Epilepsy, Ali̇şan Burak Yaşar, Ceyhun Sayman, Serap Erdoğan Taycan, Yilmaz Çeti̇nkaya, Anil Gündüz, Hülya Ti̇reli̇
Turkish Journal of Medical Sciences
Background/aim: Epilepsy is a common chronic neurological problem that impairs daily activities, functionality, and quality of life. Childhood traumas (CTs) are known to be critical factors in the onset or development of many psychiatric and medical disorders. They also play a critical role in the development of temperament and personality. This study aimed to investigate the association between CTs and common temperament patterns and features seen in epilepsy patients. Materials and methods: The study included 38 patients who were diagnosed with juvenile myoclonic epilepsy (JME) and volunteered to participate in the study. In addition to the sociodemographic form and questions …
Oxidative Stress Parameters In Patients With Ascending Aortic Dilatation, Mehmet Erdoğan, Meli̇ke Polat, Muhammet Ci̇hat Çeli̇k, Selçuk Öztürk, Serdal Baştuğ, Yunus Emre Özbebek, Sali̇m Neşeli̇oğlu, Murat Akçay
Oxidative Stress Parameters In Patients With Ascending Aortic Dilatation, Mehmet Erdoğan, Meli̇ke Polat, Muhammet Ci̇hat Çeli̇k, Selçuk Öztürk, Serdal Baştuğ, Yunus Emre Özbebek, Sali̇m Neşeli̇oğlu, Murat Akçay
Turkish Journal of Medical Sciences
Background/aim: This study aimedto determine plasma thiol, disulphide, and serum ischemia-modified albumin (IMA) levels and ferroxidase activity in patients with ascending aorta dilatation (AAD) in comparison to those without AAD and to evaluate the predictive value of these oxidative stress parameters for AAD.Materials and methods: This study was designed as a cross-sectional study of 184 patients who applied to our cardiology clinic. Our study population consisted of patients with AAD (n = 85) and without AAD (n = 99). A spectrophotometric method was used to determine plasma thiol, disulphide, and serum IMA levels and ferroxidase activity.Results: The native thiol and …
He Utility Of Synovial Fluid Levels Of Adamts9 And Adamts4 In Predicting Treatment Responses To Intraarticular Steroid Injections In Patients With Knee Osteoarthritis, Kenan Özler
Turkish Journal of Medical Sciences
Background/aim: This study aims to identify the role of synovial fluid levels of a disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) and a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4) for the prediction of intraarticular steroid injection success in knee osteoarthritis (OA).Material and methods: A total of eighty-four advanced stage knee OA patients (42 with stage 3 OA and 42 with stage 4 OA) were enrolled in the study. Baseline and posttreatment outcomes were determined using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Pretreatment synovial fluid ADAMTS9 and ADAMTS4 levels were measured by enzyme linked immunosorbent assay …
The Triglyceride-Glucose Index Predicts Peripheral Artery Disease Complexity, Bi̇lge Duran Karaduman, Hüseyi̇n Ayhan, Telat Keleş, Engi̇n Bozkurt
The Triglyceride-Glucose Index Predicts Peripheral Artery Disease Complexity, Bi̇lge Duran Karaduman, Hüseyi̇n Ayhan, Telat Keleş, Engi̇n Bozkurt
Turkish Journal of Medical Sciences
Background/aim: High levels of triglyceride (TG) and fasting blood glucose (FBG) values increase atherosclerosis risk. This study evaluates the relationship between peripheral artery disease (PAD) severity and complexity, as assessed by TransAtlantic InterSociety Consensus-II (TASC-II) classification and the triglyceride-glucose (TyG) index.Materials and methods: A total of 71 consecutive patients with PAD (males 93%, mean age 63.3 ± 9.7), who underwent percutaneous peripheral intervention were included retrospectively. The patients were divided into two groups according to the angiographically detected lesions. Those with TASC A-B lesions were included in Group 1, and those with TASC C-D lesions were included in Group 2. …