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Full-Text Articles in Medicine and Health Sciences
Evaluation Of The Effects Of Locally Applied Rosuvastatin On Bone Formation In A Threedimensional Reconstruction Rabbit Xenograft Model, Taha Özer, Alper Aktaş, Canseda Avağ, Ayşegül Firat, Mert Ocak, Fevzi̇ye Fi̇gen Kaymaz, Hakan Hamdi̇ Çeli̇k
Evaluation Of The Effects Of Locally Applied Rosuvastatin On Bone Formation In A Threedimensional Reconstruction Rabbit Xenograft Model, Taha Özer, Alper Aktaş, Canseda Avağ, Ayşegül Firat, Mert Ocak, Fevzi̇ye Fi̇gen Kaymaz, Hakan Hamdi̇ Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: Guided bone regeneration (GBR) is commonly performed to repair bone defects, and rigid occlusive titanium barriers play a vital role in bone formation in regions with no prior bone tissue. The statin, rosuvastatin (RSV), strongly affects bone apposition when applied locally. Here, we aimed to evaluate the anabolic effects of locally applied RSV with a xenograft placed on rabbit calvaria. Materials and methods: Two rigid occlusive titanium caps were used in 16 rabbits after decorticating the calvarial bone. In the control group, the area under the cap was filled with a xenograft, while in the RSV group, a xenograft …
Perspectives For Immune Plasma Treatment Of Covid-19, Başak Sayinalp, Olgu Erki̇n Çinar, İbrahi̇m Celaletti̇n Haznedaroğlu
Perspectives For Immune Plasma Treatment Of Covid-19, Başak Sayinalp, Olgu Erki̇n Çinar, İbrahi̇m Celaletti̇n Haznedaroğlu
Turkish Journal of Medical Sciences
Background/aim: The SARS-CoV-2 infection was declared as a pandemic by the World Health Organization (WHO) on March 11, 2020, and the death toll from COVID-19, which is the disease caused by SARS-CoV-2, has already surpassed that of many previous epidemics. A wide variety of treatment options are being considered for COVID-19, but there is still no definitive treatment or vaccine. This study aims to explain the background of convalescent plasma (CP) treatment and its relations with COVID-19 immunity, to define ideal treatment procedures, and to reveal present and future perspectives in the light of the rapidly growing data. Immunological basis …
Comparison Of The Clinical And Sonographic Effects Of Ultrasound Therapy, Extracorporealshock Wave Therapy, And Kinesio Taping In Lateral Epicondylitis, Tarik Özmen, Sali̇h Süha Koparal, Özlem Karataş, Fi̇li̇z Eser, Bülent Özkurt, Tuba Ümi̇t Gafuroğlu
Comparison Of The Clinical And Sonographic Effects Of Ultrasound Therapy, Extracorporealshock Wave Therapy, And Kinesio Taping In Lateral Epicondylitis, Tarik Özmen, Sali̇h Süha Koparal, Özlem Karataş, Fi̇li̇z Eser, Bülent Özkurt, Tuba Ümi̇t Gafuroğlu
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to compare the clinical and sonographic effects of the ultrasound (US) therapy, extracorporeal shock wave therapy (ESWT), and Kinesio taping (KT) in the lateral epicondylitis (LE). Materials and methods: A total of 40 patients with LE were included in the present study. The patients were randomly assigned to 3 treatment groups: US (n = 13), ESWT (n = 14), and KT (n = 13) groups. Results: The visual analog scale (VAS) scores significantly decreased in all groups (P < 0.05). Grip strength significantly increased after 8 weeks in only the KT group (P < 0.05). The Patient-Rated Tennis Elbow Evaluation Scale (PRTEE) scores significantly decreased after 2 weeks and after 8 weeks in the US group and ESWT groups, and after 8 weeks in the KT group (P < 0.05). Common extensor tendon (CET) thicknesses significantly decreased after 8 weeks in only the ESWT group (P < 0.05). Conclusion: The US therapy, KT, and ESWT are effective in reducing pain and improving functionality. However, none of these treatment methods were found to be superior to others in reducing the pain and improving functionality.
Utility Of The Pleth Variability Index In Predicting Anesthesia-Induced Hypotension Ingeriatric Patients, Ahmet Yüksek
Utility Of The Pleth Variability Index In Predicting Anesthesia-Induced Hypotension Ingeriatric Patients, Ahmet Yüksek
Turkish Journal of Medical Sciences
Background/aim: Anesthesia-induced hypotension may have negative consequences in geriatric patients. Therefore, predicting hypotension remains an important topic for anesthesiologists. Pleth Variability Index (PVI) measurement provides information about the fluid status and vascular tonus of patients. In this study, the ability of the Pleth Variability Index to predict hypotension after general anesthesia induction was evaluated. Materials and methods: PVI values obtained from pulse oximetry were recorded, in addition to preoperative standard anesthesia monitoring. The correlation between the PVI value and mean arterial pressure (MAP), systolic arterial blood pressure (SAP) changes, and the power of PVI values to predict the incidence of …
Magnetic Resonance Imaging Histogram Analysis Of Corpus Callosum In A Functionalneurological Disorder, Sema Baykara, Murat Baykara, Osman Mermi̇, Hanefi̇ Yildirim, Murad Atmaca
Magnetic Resonance Imaging Histogram Analysis Of Corpus Callosum In A Functionalneurological Disorder, Sema Baykara, Murat Baykara, Osman Mermi̇, Hanefi̇ Yildirim, Murad Atmaca
Turkish Journal of Medical Sciences
Background/aim: The aim of the present study was to examine and compare the corpus callosum (CC) via histogram analysis (HA) on T1-weighted MR images of patients diagnosed with Functional Neurological Disorder (FND) and healthy controls. Materials and methods: The study group included 19 female patients diagnosed with FND, and the control group included 20 healthy subjects. All participants were scanned with a 1.5 T MR scanner. A high-resolution structural image of the entire brain was obtained with sagittal 3D spiral fast spin echo T1-weighted images. Gray level intensity, standard deviation of the histogram, entropy, uniformity, skewness, and kurtosis values were …
Continuous Renal Replacement Therapy In Critically Ill Children: Single-Center Experience, Gül Hati̇ce Erkol Tuncer, Mesi̇ha Eki̇m, Emel Okulu, Begum Atasay, Tanil Kendi̇rli̇
Continuous Renal Replacement Therapy In Critically Ill Children: Single-Center Experience, Gül Hati̇ce Erkol Tuncer, Mesi̇ha Eki̇m, Emel Okulu, Begum Atasay, Tanil Kendi̇rli̇
Turkish Journal of Medical Sciences
Background/aim: Continuous renal replacement therapy (CRRT) has significant benefits in the treatment of critically ill children. The objective of this study is to describe the treatment indications, methods, demographics, and outcome of the patients who received CRRT in our pediatric intensive care unit and neonatal care unit, and, according to these results, we also aim to make improvements in our unit-based interventions. Material and methods: In this single-centered study, we retrospectively evaluated medical charts of the patients admitted to our intensive care units and received CRRT between February 2010 and November 2015. Results: Fifty of 60 patients were included in …
Evaluation Of Initial Chest Computed Tomography (Ct) Findings Of Covid-19pneumonia In 117 Deceased Patients: A Retrospective Study, Yasemi̇n Gündüz, Oğuz Karabay, Ali̇ Fuat Erdem, Erbi̇l Arik, Mehmet Hali̇l Öztürk
Evaluation Of Initial Chest Computed Tomography (Ct) Findings Of Covid-19pneumonia In 117 Deceased Patients: A Retrospective Study, Yasemi̇n Gündüz, Oğuz Karabay, Ali̇ Fuat Erdem, Erbi̇l Arik, Mehmet Hali̇l Öztürk
Turkish Journal of Medical Sciences
Background/aim: There is no study in the literature in which only chest computed tomography (CT) findings of deceased cases obtained at admission were examined, and the relationship between these findings and mortality was evaluated. Materials and methods: In this retrospective study, a total of 117 deceased patients with COVID-19 infection confirmed by positive polymerase chain reaction and undergone chest CT were enrolled. We evaluated initial chest CT findings and their relationship, location, prevalence, and the frequency with mortality. Results: The mean age of patients was 73 ±18 years; 71 of all patients were male and 46 were female. The predominant …
Impact Of Hospital-Acquired Acute Kidney Injury On Covid-19 Outcomes In Patients Withand Without Chronic Kidney Disease: A Multicenter Retrospective Cohort Study, Savaş Öztürk, Kenan Turgutalp, Mustafa Arici, Hakki Çeti̇nkaya, Mehmet Riza Altiparmak, Zeki̇ Aydin, Zeki̇ Soypaçaci, Feyza Bora, Ekrem Kara, Egemen Cebeci̇, Tuba Eli̇f Özler, Mürşi̇de Esra Dölarslan, Savaş Si̇pahi̇, Yavuz Ayar, İdri̇s Şahi̇n
Impact Of Hospital-Acquired Acute Kidney Injury On Covid-19 Outcomes In Patients Withand Without Chronic Kidney Disease: A Multicenter Retrospective Cohort Study, Savaş Öztürk, Kenan Turgutalp, Mustafa Arici, Hakki Çeti̇nkaya, Mehmet Riza Altiparmak, Zeki̇ Aydin, Zeki̇ Soypaçaci, Feyza Bora, Ekrem Kara, Egemen Cebeci̇, Tuba Eli̇f Özler, Mürşi̇de Esra Dölarslan, Savaş Si̇pahi̇, Yavuz Ayar, İdri̇s Şahi̇n
Turkish Journal of Medical Sciences
Background/aim: Hospital-acquired acute kidney injury (HA-AKI) may commonly develop in Covid-19 patients and is expected to have higher mortality. There is little comparative data investigating the effect of HA-AKI on mortality of chronic kidney disease (CKD) patients and a control group of general population suffering from Covid-19. Materials and methods: HA-AKI development was assessed in a group of stage 3-5 CKD patients and control group without CKD among adult patients hospitalized for Covid-19. The role of AKI development on the outcome (in-hospital mortality and admission to the intensive care unit [ICU]) of patients with and without CKD was compared. Results: …
Treatment Of Hypothyroidism Improves Glomerular Filtration Rate (Gfr) In Geriatricpatients, Mert Eşme, Oktay Bulur, Mehmetcan Atak, Cafer Balci, Kürşat Dal, Derun Taner Ertuğrul, Zeli̇ha Günnur Di̇kmen, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Burcu Balam Doğu
Treatment Of Hypothyroidism Improves Glomerular Filtration Rate (Gfr) In Geriatricpatients, Mert Eşme, Oktay Bulur, Mehmetcan Atak, Cafer Balci, Kürşat Dal, Derun Taner Ertuğrul, Zeli̇ha Günnur Di̇kmen, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Burcu Balam Doğu
Turkish Journal of Medical Sciences
Background/aim: Renal function of patients with hypothyroidism increases after reaching euthyroid state. There is no data regarding geriatric age group. The aim of the study was determined to investigate whether renal function of geriatric patients with hypothyroidism increases after they become euthyroid. Materials and methods: Patients who were sixty-five years or older were retrospectively screened in two centers. TSH, T3, T4, creatinine, and eGFR calculated by CKD-EPI formula were recorded under the presence of accompanying hypothyroidism. The same variables were recorded after the patients became euthyroid. Results: 285 patients were included in the study, the median age was 73(65-84), and …
What Is The Consistency Between The Results Of Needle Biopsy And Prostatectomy Specimenpathology Results' A Pilot Study, Ömer Ozan Yildizli, İbrahi̇m Üntan, Deni̇z Demi̇rci̇
What Is The Consistency Between The Results Of Needle Biopsy And Prostatectomy Specimenpathology Results' A Pilot Study, Ömer Ozan Yildizli, İbrahi̇m Üntan, Deni̇z Demi̇rci̇
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to establish the relationship between the needle biopsy and the pathology result after radical prostatectomy administrated for prostate cancer. Materials and methods: We retrospectively analyzed 67 patients who had undergone radical prostatectomy from 2016 to 2019. All surgeries and all biopsies were performed in the third author's urology department. Samples were collected through 12-core biopsy under local anesthesia. All specimens were studied in the pathology department of the third author's center. The results evaluated were needle biopsies' Gleason scores and prostatectomy specimens' Gleason scores. Results: Inclusion criteria were not having any neo-adjuvant treatment …
The Effect Of Ankaferd Blood Stopper On Liver Damage In Experimental Obstructivejaundice, Koray Koşmaz, Abdullah Durhan, Marlen Süleyman, Yilmaz Ünal, Mustafa Taner Bostanci, Tuğba Yi̇ği̇t Haskaraca, Can Ersak, Mehmet Şeneş, İlknur Alkan Kuşabbi̇, Eylem Pinar Eser, Sema Hücümenoğlu
The Effect Of Ankaferd Blood Stopper On Liver Damage In Experimental Obstructivejaundice, Koray Koşmaz, Abdullah Durhan, Marlen Süleyman, Yilmaz Ünal, Mustafa Taner Bostanci, Tuğba Yi̇ği̇t Haskaraca, Can Ersak, Mehmet Şeneş, İlknur Alkan Kuşabbi̇, Eylem Pinar Eser, Sema Hücümenoğlu
Turkish Journal of Medical Sciences
Background/aims: To evaluate the potential protective effects of Ankaferd blood stopper (ABS) in an experimental obstructive jaundice (OJ) model. Materials and methods: The study included 26 female rats, which were divided into 3 groups. The sham group, consisting of 10 rats, (group 1) only received solely laparotomy. In the control group, consisting of 8 rats, (group 2), ligation was applied to the biliary tract and no treatment was implemented. In the treatment group, consisting of 8 rats, (group 3), following ligation of biliary tract, 0.5 mL/day ABS was given for 10 days. Liver tissue and blood samples were taken for …
Effects Of The Covid-19 Pandemic On Psychology And Disease Activity In Patients Withankylosing Spondylitis And Rheumatoid Arthritis, Şaki̇r Gica, Yasemi̇n Akkubak, Zaki̇re Kübra Aksoy, Adem Küçük, Erkan Cüre
Effects Of The Covid-19 Pandemic On Psychology And Disease Activity In Patients Withankylosing Spondylitis And Rheumatoid Arthritis, Şaki̇r Gica, Yasemi̇n Akkubak, Zaki̇re Kübra Aksoy, Adem Küçük, Erkan Cüre
Turkish Journal of Medical Sciences
Background/aim: The COVID-19 outbreak is known to increase stress levels of most patients with chronic diseases. Patients with ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are highly susceptible to environmental stress. In the current study, we aimed to determine how the COVID-19 pandemic psychologically affected patients with chronic progressive diseases such as AS and RA and the effects of these psychological factors on disease activity. Materials and methods: Age and sex-matched patients with AS (n = 80), RA (n = 80), and healthy controls (n = 80) were included in the study. All participants were evaluated with the "Perceived COVID-19 …
Role Of Frailty In Prediction Of Hospitalized Older Adult Patient's Outcomes: A Prospective Study, Maryam Chehrehgosha, Reza Fadaye Vatan, Mahtab Alizadeh Khoei, Farshad Sharifi, Reyhaneh Aminalroaya, Zahra Vahabi, Abolfazl Zendedel, Hamidreza Hekmat
Role Of Frailty In Prediction Of Hospitalized Older Adult Patient's Outcomes: A Prospective Study, Maryam Chehrehgosha, Reza Fadaye Vatan, Mahtab Alizadeh Khoei, Farshad Sharifi, Reyhaneh Aminalroaya, Zahra Vahabi, Abolfazl Zendedel, Hamidreza Hekmat
Turkish Journal of Medical Sciences
Background/aim: Frailty is associated with an increased risk of negative short-term and long-term hospital outcomes. This study aimed to evaluate the role of frailty in predicting readmission, length of stay, and quality of life in the hospitalized older adults. Materials and methods: This observational study was conducted at Ziaiyan Hospital, Tehran, Iran. In total, 304 participants (65-85 years), were enrolled through the inclusion criteria from August to December 2019. The frailty index (FI) was assessed by the minimum data set-home care. Readmission was obtained through telephone interviews. The length of stay was gathered by the patient's hospital records, and the …
Dual Energy Ct In Necrotizing Enterocolitis; A Novel Diagnostic Approach, Özgür Çağlar, Emrullah Cesur, Recep Sade, Bi̇nali̇ Firinci, Mustafa Kara, Mehmet Emi̇n Çeli̇kkaya, Akgün Oral, Murat Yi̇ği̇ter, Sevi̇lay Özmen
Dual Energy Ct In Necrotizing Enterocolitis; A Novel Diagnostic Approach, Özgür Çağlar, Emrullah Cesur, Recep Sade, Bi̇nali̇ Firinci, Mustafa Kara, Mehmet Emi̇n Çeli̇kkaya, Akgün Oral, Murat Yi̇ği̇ter, Sevi̇lay Özmen
Turkish Journal of Medical Sciences
Background/aim: Necrotizing enterocolitis (NEC) is one of the most important causes of morbidity and mortality in premature infants. Although there are no specific diagnostic tools, the main factors affecting prognosis are clinical and laboratory findings, and early diagnosis and treatment. In this study, we demonstrate the importance of dual-energy computed tomography (DECT) in confirming intestinal ischemia in neonates with NEC. Materials and methods: Patients diagnosed with NEC in a neonatal intensive care unit were staged according to modified Bell's classification, and DECT was performed on patients with NEC stages 2-A, 2-B and 3-A. According to their DECT reports, these patients …
Pulse Steroid Treatment For Hospitalized Adults With Covid-19, Ayşe Batirel, Recep Demi̇rhan, Nurullah Eser, Ezgi̇ Körlü, Mehmet Engi̇n Tezcan
Pulse Steroid Treatment For Hospitalized Adults With Covid-19, Ayşe Batirel, Recep Demi̇rhan, Nurullah Eser, Ezgi̇ Körlü, Mehmet Engi̇n Tezcan
Turkish Journal of Medical Sciences
Background/aim: High-dose steroid has been shown to reduce the mortality rate in Corona virus disease 2019 (COVID-19) patients who need oxygen support. Here, we evaluated the effectiveness of pulse-steroid in case of unresponsiveness to treatment with high dose steroid. Materials and methods: The study is a retrospective controlled trial. We divided the patients in 3 groups: standard-care therapy alone, high-dose steroid treatment (6 mg/day dexamethasone equivalent), and pulse-steroid treatment (250 mg/day methyl-prednisolone). One hundred and fifty patients were enrolled in each group. All patients were hospitalized and needed oxygen support. We matched the patients according to disease severity at the …
Galectin-3: Can It Be A Diagnostic Tool For Pneumonia In Covid-19 Patients?, Emi̇ne Kartal Baykan, Engi̇n Şebi̇n, Ömer Karaşahi̇n, Ahmed Rami̇z Baykan, Serkan Cerrah, Hasan Göğebakan, Can Sevi̇nç, Mustafa Kahraman, Yasemi̇n Coşkun Yavuz
Galectin-3: Can It Be A Diagnostic Tool For Pneumonia In Covid-19 Patients?, Emi̇ne Kartal Baykan, Engi̇n Şebi̇n, Ömer Karaşahi̇n, Ahmed Rami̇z Baykan, Serkan Cerrah, Hasan Göğebakan, Can Sevi̇nç, Mustafa Kahraman, Yasemi̇n Coşkun Yavuz
Turkish Journal of Medical Sciences
Background/aim: Biochemical markers are needed to show lung involvement in COVID-19 disease. Galectin-3 is known to play a key role in the inflammation and fibrosis process. We aimed to evaluate the predictive role of galectin-3 levels for pneumonia in patients with COVID-19. Materials and methods: Total of 176 patients with COVID-19, confirmed with reverse transcriptase polymerase chain reaction, admitted to the Erzurum Regional Training and Research Hospital was analyzed. The study was designed as a cross sectional. The baseline data of laboratory examinations, including galectin-3 were collected at the time of diagnosis. CT images evaluated by a single radiologist according …
A Single Center Survey Study Of Systemic Vasculitis And Covid-19 During The First Months Of Pandemic, Burak İnce, Murat Bektaş, Nevzat Koca, Besi̇m Fazil Ağargün, Si̇bel Zarali, Damla Yenersu Güzey, Ayşe İnce, Mehmet Sali̇h Sevdi̇, Yasemi̇n Yalçinkaya, Bahar Artim Esen, Ahmet Gül, Mahdume Lale Öçal, Murat İnanç
A Single Center Survey Study Of Systemic Vasculitis And Covid-19 During The First Months Of Pandemic, Burak İnce, Murat Bektaş, Nevzat Koca, Besi̇m Fazil Ağargün, Si̇bel Zarali, Damla Yenersu Güzey, Ayşe İnce, Mehmet Sali̇h Sevdi̇, Yasemi̇n Yalçinkaya, Bahar Artim Esen, Ahmet Gül, Mahdume Lale Öçal, Murat İnanç
Turkish Journal of Medical Sciences
Backgroun/aim: COVID-19 pandemic created concerns among patients receiving immunosuppressive therapy. Frequency of COVID-19 and impact of lockdown on treatment compliance in patients with vasculitis are largely unknown. Materials Method: Patients with ANCA-associated and large vessel vasculitis that have been followed-up in our clinic were contacted by phone and a questionnaire containing home isolation status, treatment adherence and history of COVID-19 between March 1st and June 30th, 2020 was applied. Results: The survey was applied to 103 patients (F/M: 59/44, mean age: 53.2±12.5). Thirty-three (32%) patients didn't attend at least one appointment; 98(95.1%) noted that they spent 3 months in home …
Clinical Characteristics And Risk Factors For 28-Day Mortality In Critically Ill Patients With Covid-19: A Retrospective Cohort Study, Mehmet Nuri̇ Yakar, Begüm Ergan, Bi̇şar Ergün, Murat Küçük, Ali̇ Cantürk, Mahmut Cem Ergon, Naci̇ye Si̇nem Gezer, Erdem Yaka, Bi̇lgi̇n Cömert, Ali̇ Necati̇ Gökmen
Clinical Characteristics And Risk Factors For 28-Day Mortality In Critically Ill Patients With Covid-19: A Retrospective Cohort Study, Mehmet Nuri̇ Yakar, Begüm Ergan, Bi̇şar Ergün, Murat Küçük, Ali̇ Cantürk, Mahmut Cem Ergon, Naci̇ye Si̇nem Gezer, Erdem Yaka, Bi̇lgi̇n Cömert, Ali̇ Necati̇ Gökmen
Turkish Journal of Medical Sciences
Background: To date, the coronavirus disease 2019 (COVID-19) caused more than 2.6 million deaths all around the world. Risk factors for mortality remain unclear. The primary aim was to determine the independent risk factors for 28-day mortality. Materials and Methods: In this retrospective cohort study, critically ill patients (≥ 18 years) who were admitted to the intensive care unit due to COVID-19 were included. Patient characteristics, laboratory data, radiologic findings, treatments, and complications were analyzed in the study. Results: A total of 249 patients (median age 71, 69.1% male) were included in the study. 28-day mortality was 67.9% (n = …
Reliability And Validity Of The Turkish Version Of Post-Covid-19 Functional Status Scale, Ebru Çalik Kütükcü, Aslihan Çakmak, Esra Kinaci, Oğuz Abdullah Uyaroğlu, Naci̇ye Vardar Yağli, Gülay Sai̇n Güven, Melda Sağlam, Lale Özişik, Nursel Çalik Başaran, Deni̇z İnal İnce
Reliability And Validity Of The Turkish Version Of Post-Covid-19 Functional Status Scale, Ebru Çalik Kütükcü, Aslihan Çakmak, Esra Kinaci, Oğuz Abdullah Uyaroğlu, Naci̇ye Vardar Yağli, Gülay Sai̇n Güven, Melda Sağlam, Lale Özişik, Nursel Çalik Başaran, Deni̇z İnal İnce
Turkish Journal of Medical Sciences
Background/aim: The post-COVID-19 Functional Status (PCFS) has recently been developed for functional outcomes of COVID-19 upon discharge and in long term. The purpose of this study was to investigate the reliability and validity properties of the Turkish version of the PCFS in Turkish post-COVID-19 patients with hospitalized and nonhospitalized during infection. Materials and methods: One hundred participants with post-COVID-19 were included in this cross-sectional study. Test-retest reliability of the Turkish version of PCFS assessed by intraclass correlation coefficient (ICC) and Cronbach's alpha was calculated for internal consistency. For construct validity, correlation coefficients between the Turkish version of PCFS developed by …
Intraoperative Ultrasound Imaging And Sono-Scintigraphic Concordance Improvessuccess Rates Of Minimally Invasive Parathyroidectomy, Rabi̇ye Uslu Erdemi̇r, İlhan Taşdöven, Taner Bayraktaroğlu, Güldeni̇z Karadeni̇z Çakmak
Intraoperative Ultrasound Imaging And Sono-Scintigraphic Concordance Improvessuccess Rates Of Minimally Invasive Parathyroidectomy, Rabi̇ye Uslu Erdemi̇r, İlhan Taşdöven, Taner Bayraktaroğlu, Güldeni̇z Karadeni̇z Çakmak
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the effect of sono-scintigraphic correlation on the success of minimal invasive parathyroidectomy (MIP) via surgeon performed continuous intraoperative sonographic guidance in patients operated for primary hyperparathyroidism (PHPT) without intact parathormone (PTH) measurement. Materials and methods: A retrospective analysis of a prospective database was conducted to review patients who underwent MIP (July 2017-October 2019). The screened parameters were preoperative PTH level, preoperative ultrasonography (US), preoperative scintigraphy, intraoperative US, intraoperative frozen section analysis, postoperative PTH level, and permanent pathology report. Intraoperative intact PTH measurement was not employed due to institutional policy. Results: Preoperative US alone localized …
Low Immunity Against Vaccine Preventable Diseases In Turkish Hiv Cohort, Aslihan Candevi̇r, Feri̇t Kuşcu, Fi̇gen Yildirim, Süheyla Kömür, Gönül Çi̇çek Şentürk, Ayşe Seza İnal, Fatma Eser, Sali̇h Çeti̇ner, Behi̇ce Kurtaran, Yeşi̇m Taşova
Low Immunity Against Vaccine Preventable Diseases In Turkish Hiv Cohort, Aslihan Candevi̇r, Feri̇t Kuşcu, Fi̇gen Yildirim, Süheyla Kömür, Gönül Çi̇çek Şentürk, Ayşe Seza İnal, Fatma Eser, Sali̇h Çeti̇ner, Behi̇ce Kurtaran, Yeşi̇m Taşova
Turkish Journal of Medical Sciences
Background/aim: HIV infection increase the risk of serious disease resulting from common vaccine-preventable infections. Vaccinations are particularly important for HIV infected adults. We aimed to investigate the immunity rates against measles, mumps, rubella, hepatitis A, B, and tetanus in newly diagnosed HIV patients. Materials and methods: Patients who admitted to outpatient clinics of three centers with newly diagnosed HIV infection, between 1 January 2015 and 31 June 2017 were included. Measles, mumps, rubella, varicella zoster virus, hepatitis A, hepatitis B, and tetanus antibody levels were measured by commercial diagnostic kits. Demographical and laboratory data of the patients were recorded. Results: …
History Repeats Itself: Horse Originated Hyperimmune Sera Production Against Sars Cov-2, Ahu Pakdemi̇rli̇, Elvi̇n Çalişkan, Sabri̇ Hacioğlu, Erdem Danyer, Özlem Kardoğan, Züleyha Ergün Kurt, Özcan Yildirim, Hakan Taşkaya, Bora Ündar, Yasemi̇n Sezgi̇n, Gencay Ergi̇n, Hi̇mmet Eki̇ci̇, Ufuk Ülker, Erkan Taçbaş, Şahi̇n Çakir
History Repeats Itself: Horse Originated Hyperimmune Sera Production Against Sars Cov-2, Ahu Pakdemi̇rli̇, Elvi̇n Çalişkan, Sabri̇ Hacioğlu, Erdem Danyer, Özlem Kardoğan, Züleyha Ergün Kurt, Özcan Yildirim, Hakan Taşkaya, Bora Ündar, Yasemi̇n Sezgi̇n, Gencay Ergi̇n, Hi̇mmet Eki̇ci̇, Ufuk Ülker, Erkan Taçbaş, Şahi̇n Çakir
Turkish Journal of Medical Sciences
Background/aim: SARS-CoV-2 disease was announced as a pandemic by The World Health Organization in early 2020. It is still threatening the world population. Here, we aimed to produce hyperimmune sera that contain immunoglobulin G and F(ab')2 fragments sourced from horse antibodies as an urgent response to the pandemic. Materials and methods: SARS-CoV-2 was produced and inactivated with three different methods [formaldehyde (FA), formaldehyde, and binary ethylene amine (FA + BEI), and heat treatment]. After in vitro inactivation control, immunogens were mixed with Freund's adjuvant, thereafter horses (n: 2 for FA, 4 for FA + BEI, 2 for heat inactivation) and …
Association Of Physical Frailty With Cognitive Function And Mood In Older Adults Without Dementia And Depression, Rana Tuna Doğrul, Hacer Doğan Varan, Muhammet Cemal Kizilarslanoğlu, Mustafa Kemal Kiliç, Özgür Kara, Güneş Arik, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Burcu Balam Doğu
Association Of Physical Frailty With Cognitive Function And Mood In Older Adults Without Dementia And Depression, Rana Tuna Doğrul, Hacer Doğan Varan, Muhammet Cemal Kizilarslanoğlu, Mustafa Kemal Kiliç, Özgür Kara, Güneş Arik, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Burcu Balam Doğu
Turkish Journal of Medical Sciences
Background/aim: Physical frailty is thought to be related with a decline in cognitive function, mood, and social activities, especially in patients with depression and dementia. It is not clear whether or not physical frailty is associated with an impairment in cognitive function and mood in patients without dementia and depression. In this study, we evaluated the association of physical frailty with cognitive function and mood in geriatric patients without dementia and depression. Material and methods: In this study, 612 patients aged 65 years and over were evaluated. Physical frailty was assessed by using Fried criteria. Furthermore, comprehensive geriatric assessment was …
A Novel Marker Of Systemic Inflammation In Psoriasis And Related Comorbidities: Chitotriosidase, Bi̇lal İlanbey, Ömer Faruk Elmas, Eser Yildirim Sözmen, Ümran Günay, Abdullah Demi̇rbaş, Mustafa Atasoy, Ümi̇t Türsen, Torello Lotti̇
A Novel Marker Of Systemic Inflammation In Psoriasis And Related Comorbidities: Chitotriosidase, Bi̇lal İlanbey, Ömer Faruk Elmas, Eser Yildirim Sözmen, Ümran Günay, Abdullah Demi̇rbaş, Mustafa Atasoy, Ümi̇t Türsen, Torello Lotti̇
Turkish Journal of Medical Sciences
Background/aim: Chitotriosidase (ChT) is an enzyme secreted by activated macrophages and neutrophils in response to proinflammatory signals. There is growing evidence indicating that ChT activity reflects the systemic inflammatory status. This study aimed to investigate whether serum ChT activity increased in patients with psoriasis and related comorbidities. Materials and methods: This cross-sectional study included 53 (28 with associated comorbidities and 25 without comorbidities) patients with psoriasis and 52 healthy volunteers. All participants underwent laboratory investigations for serum ChT levels, complete blood count, erythrocyte sedimentation rate, C-reactive protein, and serum lipid levels. Results: The patients with psoriasis showed significantly higher levels …
Risk Factors Related To The Size And Volume Of Femoral Artery Pseudoaneurysm Aftercatheter Angiography: A Single-Center-Study, Özgür Çakir, Zeki̇ Talas, Duygu Temi̇z Karadağ, Ayşegül Durmaz, İsa Çam, Ercüment Çi̇ftçi̇, Mühi̇p Kanko
Risk Factors Related To The Size And Volume Of Femoral Artery Pseudoaneurysm Aftercatheter Angiography: A Single-Center-Study, Özgür Çakir, Zeki̇ Talas, Duygu Temi̇z Karadağ, Ayşegül Durmaz, İsa Çam, Ercüment Çi̇ftçi̇, Mühi̇p Kanko
Turkish Journal of Medical Sciences
Background/aim: Evaluate the risk factors associated with pseudoaneurysms' development after the percutaneous interventional procedures performed by cardiology, interventional radiology (IR), and the other clinics. Materials and methods: We retrospectively analyzed the ultrasound scans in the hospital database and picture archiving system (PACS) and enrolled a total of 132 patients during the period from October 2015 and December 2019. We evaluated the maximum diameter and volume of the pseudoaneurysm with the patient and procedure-related factors with univariate analysis. Results: We found that the patients with hypertension and without peripheric artery disease (PAD) had greater sac diameter (p = 0.010 and p …
Differences In Corpus Callosum Morphology Between Healthy Adolescents Andadolescents With Migraine: A Case Control Study, Mustafa Emre Akin, Ayşegül Neşe Çitak Kurt
Differences In Corpus Callosum Morphology Between Healthy Adolescents Andadolescents With Migraine: A Case Control Study, Mustafa Emre Akin, Ayşegül Neşe Çitak Kurt
Turkish Journal of Medical Sciences
Background/aim: This study objected to compare the measurements of corpus callosum substructures of adolescents with migraine and healthy adolescents. Materials and methods: In a case-control design, adolescents aged 12-18 years with the diagnosis of migraine and healthy control group had brain magnetic resonance imaging examination. The CC dimensions including anteroposterior length, truncus, genu and splenium widths of the case and control groups were measured and compared. Results: The sample consisted of 188 adolescents, 109 girls (58.0%), and 79 boys (42.0%). Of these 87 (46.3%) were in the migraine group and 101 (53.7%) were in the healthy control group. The mean …
Non-Adherence To Colchicine Treatment Is A Common Misevaluation In Familialmediterranean Fever, Emre Tekgöz, Seda Çolak, Fatma İlknur Çinar, Sedat Yilmaz, Muhammet Çinar
Non-Adherence To Colchicine Treatment Is A Common Misevaluation In Familialmediterranean Fever, Emre Tekgöz, Seda Çolak, Fatma İlknur Çinar, Sedat Yilmaz, Muhammet Çinar
Turkish Journal of Medical Sciences
Background/aim: Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease that requires lifelong colchicine treatment. Colchicine is the mainstay of the treatment, which decreases the frequency and the severity of recurrent FMF attacks and prevents the development of amyloidosis. This study aimed to investigate the rates of colchicine treatment adherence in patients with FMF and the factors related to treatment non-adherence. Materials and methods: This observational study was conducted with 179 patients with FMF between November 2018 and April 2019 in a tertiary rheumatology outpatient clinic. The sociodemographic and clinical data were recorded. Compliance Questionnaire on Rheumatology (CQR) was used …
Evaluation Of Serum Neutrophil Gelatinase-Associated Lipocalin (Ngal), Asymmetricdimethylarginine (Adma) And Symmetric Dimethylarginine (Sdma) Levels, And Theirrelations With Disease Type And Activity In Inflammatory Bowel Diseases, Hüseyi̇n Korkmaz, Mehmet Asil, Tuncer Temel, Bahadir Öztürk, Levent Kebapcilar
Evaluation Of Serum Neutrophil Gelatinase-Associated Lipocalin (Ngal), Asymmetricdimethylarginine (Adma) And Symmetric Dimethylarginine (Sdma) Levels, And Theirrelations With Disease Type And Activity In Inflammatory Bowel Diseases, Hüseyi̇n Korkmaz, Mehmet Asil, Tuncer Temel, Bahadir Öztürk, Levent Kebapcilar
Turkish Journal of Medical Sciences
Background/aim: Inflammatory bowel disease (IBD) mainly encompass two entities called ulcerative colitis (UC) and Crohn's disease (CD), both of which are chronic, progressive and, inflammatory conditions of the gastrointestinal tract. Various indicators and noninvasive markers have been sought and used in IBD patients to help assessing disease activity and treatment effectiveness although none of them are proven to yield definite results in full correlation with the clinical, endoscopic, and histopathological examinations. The aim of the current study was to investigate the relationship of serum neutrophil gelatinase-associated lipocalin (NGAL), asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA) levels with disease type and …
Oxygen Reserve Index Guided Oxygen Titration In One Lung Ventilation With Low Freshgas Flow, Ayten Saraçoğlu, Esra Yamansavci Şi̇rzai̇, Bedretti̇n Yildizeli̇, Mustafa Yüksel, Zeynep Zuhal Aykaç
Oxygen Reserve Index Guided Oxygen Titration In One Lung Ventilation With Low Freshgas Flow, Ayten Saraçoğlu, Esra Yamansavci Şi̇rzai̇, Bedretti̇n Yildizeli̇, Mustafa Yüksel, Zeynep Zuhal Aykaç
Turkish Journal of Medical Sciences
Background/aim: Continuous oxygen reserve index (ORI) measurement with multiple wave pulse co-oximetry is a noninvasive measurement. The decrease in the ORI trend provides a prediction for the development of hypoxemia and provides information on hyperoxia. Our aim is to determine the effect of ORI-guided oxygen titration on hyperoxemia-mediated morbidity. Materials and methods: Consecutive 120 ASA I-III patients, 18-70 years of age, without severe obstruction or restriction, undergoing one lung ventilation (OLV), were included in the study. Patients were divided into 4 groups. Oxygen titration without ORI monitoring with low-flow anesthesia (1 L/min, Group 1, n = 25) and high-flow anesthesia …
Cross-Cultural Adaptation, Reliability, And Validity Of The Turkish Version Of The Obesityspecific Quality Of Life Questionnaire: Quality Of Life, Obesity, And Dietetics (Qolod)Rating Scale, Ni̇metcan Mehmet Yağma, Egemen Ünal, Mehmet Enes Gökler, Sali̇h Mollahali̇loğlu
Cross-Cultural Adaptation, Reliability, And Validity Of The Turkish Version Of The Obesityspecific Quality Of Life Questionnaire: Quality Of Life, Obesity, And Dietetics (Qolod)Rating Scale, Ni̇metcan Mehmet Yağma, Egemen Ünal, Mehmet Enes Gökler, Sali̇h Mollahali̇loğlu
Turkish Journal of Medical Sciences
Background/aim: Obesity is one of the main public health issues in many countries including Turkey. The aim of the study is to test cross-cultural adaptation, reliability, and validity of QOLOD rating scale in the Turkish language. Materials and methods: This methodological study was conducted among the overweight and obesity people between February-March, 2018 in Ankara Atatürk Training and Research Hospital. The data was collected through self-report and face to face interviews. The QOLOD rating scale has 36 items, a 5-point Likert scale (1-5) is used for each question. Results: In the study, of the 180 participants, 101 (56.1%) were female, …