Engineering Commons^™

Effects Of Training Intensity On Locomotor Performance In Individuals With Chronic Spinal Cord Injury: A Randomized Crossover Study, Gabrielle Brazg, Meghan Fahey, Carey L. Holleran, Mark Connolly, Jane Woodward, Patrick W. Hennessy, Brian D. Schmit, T. George Hornby

Biomedical Engineering Faculty Research and Publications

Background. Many physical interventions can improve locomotor function in individuals with motor incomplete spinal cord injury (iSCI), although the training parameters that maximize recovery are not clear. Previous studies in individuals with other neurologic injuries suggest the intensity of locomotor training (LT) may positively influence walking outcomes. However, the effects of intensity during training of individuals with iSCI have not been tested. Objective. The purpose of this pilot, blinded-assessor randomized trial was to evaluate the effects of LT intensity on walking outcomes in individuals with iSCI. Methods. Using a crossover design, ambulatory participants with iSCI >1 year duration performed either …

Structurofunctional Resting-State Networks Correlate With Motor Function In Chronic Stroke, Benjamin Kalinosky, Reivian B. Barillas, Brian D. Schmit

Biomedical Engineering Faculty Research and Publications

Purpose

Motor function and recovery after stroke likely rely directly on the residual anatomical connections in the brain and its resting-state functional connectivity. Both structural and functional properties of cortical networks after stroke are revealed using multimodal magnetic resonance imaging(MRI). Specifically, functional connectivity MRI (fcMRI) can extract functional networks of the brain at rest, while structural connectivity can be estimated from white matter fiber orientations measured with high angular-resolutiondiffusion imaging (HARDI). A model that marries these two techniques may be the key to understanding functional recovery after stroke. In this study, a novel set of voxel-level measures …

How A Diverse Research Ecosystem Has Generated New Rehabilitation Technologies: Review Of Nidilrr’S Rehabilitation Engineering Research Centers, David J. Reinkensmeyer, Sarah Blackstone, Cathy Bodine, John Brabyn, David Brienza, Kevin Caves, Frank Deruyter, Edmund Durfee, Stefania Fatone, Geoff Fernie, Steven Gard, Patricia Karg, Todd A. Kuiken, Gerald F. Harris, Mike Jones, Yue Li, Jordana Maisel, Michael Mccue, Michelle A. Meade, Helena Mitchell, Tracy L. Mitzner, James L. Patton, Philip S. Requejo, James H. Rimmer, Wendy A. Rogers, W. Zev Rymer, Jon A. Sanford, Lawrence Schneider, Levin Sliker, Stephen Sprigle, Aaron Steinfeld, Edward Steinfeld, Gregg Vanderheiden, Carolee Winstein, Li-Qun Zhang, Thomas Corfman

Biomedical Engineering Faculty Research and Publications

Over 50 million United States citizens (1 in 6 people in the US) have a developmental, acquired, or degenerative disability. The average US citizen can expect to live 20% of his or her life with a disability. Rehabilitation technologies play a major role in improving the quality of life for people with a disability, yet widespread and highly challenging needs remain. Within the US, a major effort aimed at the creation and evaluation of rehabilitation technology has been the Rehabilitation Engineering Research Centers (RERCs) sponsored by the National Institute on Disability, Independent Living, and Rehabilitation Research. As envisioned at their …

Lung Injury Pathways: Adenosine Receptor 2b Signaling Limits Development Of Ischemic Bronchiolitis Obliterans Organizing Pneumonia, John C. Densmore, Terry R. Schaid, Paul M. Jeziorczak, Meetha Medhora, Said H. Audi, Shraddha Nayak, John Auchampach, Melinda R. Dwinell, Aron M. Geurts, Elizabeth R. Jacobs

Biomedical Engineering Faculty Research and Publications

Purpose/Aim of the Study: Adenosine signaling was studied in bronchiolitis obliterans organizing pneumonia (BOOP) resulting from unilateral lung ischemia. Materials and Methods: Ischemia was achieved by either left main pulmonary artery or complete hilar ligation. Sprague–Dawley (SD) rats, Dahl salt sensitive (SS) rats and SS mutant rat strains containing a mutation in the A_2B adenosine receptor gene (Adora2b) were studied. Adenosine concentrations were measured in bronchoalveolar lavage (BAL) by HPLC. A_2A (A_2AAR) and A_2B adenosine receptor (A_2BAR) mRNA and protein were quantified. Results: Twenty-four hours after unilateral PA …

Smartphone Based Optical Spectrometer For Diffusive Reflectance Spectroscopic Measurement Of Hemoglobin, Perry Edwards, Chenji Zhang, Baigang Zhang, Xiangqian Hong, Vivek K. Nagarajan, Bing Yu, Zhiwen Liu

Biomedical Engineering Faculty Research and Publications

We report a miniature, visible to near infrared G-Fresnel spectrometer that contains a complete spectrograph system, including the detection hardware and connects with a smartphone through a microUSB port for operational control. The smartphone spectrometer is able to achieve a resolution of ~5 nm in a wavelength range from 400 nm to 1000 nm. We further developed a diffuse reflectance spectroscopy system using the smartphone spectrometer and demonstrated the capability of hemoglobin measurement. Proof of concept studies of tissue phantoms yielded a mean error of 9.2% on hemoglobin concentration measurement, comparable to that obtained with a commercial benchtop spectrometer. The …

Statistical Shape Modeling To Quantify Variation In The Proximal Humeral Anatomy, Paul B. Sade Sr.

Electronic Theses and Dissertations

The fit of the humeral prosthesis to the intramedullary canal and the replication of the anatomic humeral head center are important factors in Total Shoulder Arthroplasty (TSA). The objective of this thesis was to develop a Statistical Shape Model (SSM) of the cortical and cancellous bone regions of the proximal humerus, and to assess potential shape differences with gender and ethnicity, with a goal of informing implant design. An SSM was used and Principal Component Analysis (PCA) was applied to data that represented both the cancellous and cortical humeral bone of 63 healthy subjects and cadavers. Anatomical measurements and PC …

Six Degrees Of Freedom: Kinematics Of The Healthy Ankle Syndesmosis Joint, Veronica A. Hogg-Cornejo

Electronic Theses and Dissertations

Syndesmotic injury, more commonly known as a "high ankle sprain", accounts for over 12% of all ankle sprain incidents in the US; of which, over 25% occur during a sporting activity. Typically, harm to the syndesmosis occurs in sports such as football, soccer, lacrosse, and hockey where it is common for an athlete to experience rapid and extreme dorsiflexion-external rotations of the foot. Severe syndesmotic sprains have been noted by clinicians as the most difficult ankle injury to accurately diagnose and treat, require the most recuperation time, and often results in life-long dysfunction. Even more problematic, 40% of patients suffering …

A 3d Fem Comparative Study On The Impact Response Between Human Head And Nocsae Head Due To Free Fall, Amey S. Badhe

Dissertations, Master's Theses and Master's Reports

We all enjoy sports be it watching or playing. Concussion is well known topic when it comes sports related injuries. However, concussion and brain injury is not exclusive to sports and outdoor activities. Sometimes, even the impact due to slip and fall at small heights can cause serious damage to the head and brain. This report studies the response generated in the human head model and the commercially use dummy NOCSAE headform due to drop from height of 2, 3, 4 and 5 feet. Earlier studies have related brain kinetics and head kinematics to concussion and traumatic brain injury (TBI). …

Investigation Of The Use Of 3-D Printer Platform As Building Block For Rapid Design Of Research And Manufacturing Tool, Handy Chandra

Dissertations, Master's Theses and Master's Reports

This thesis attempts to show how an open source 3-D printer platform, the self replicating rapid prototype (RepRap), could be used to accelerate the development of research and manufacturing tools. Two projects are shown as examples, both utilizing components of the 3-D printer platform.

The first project is to develop an instrument capable of performing automated large-area four-point probe measurements. A modified RepRap 3-D Printer with a four-point probe in place of the 3-D printer head is utilized as a precision positioning platform. The printer together with custom designed measurement circuit and software performs automated measurement on multiple points on …

Performance Simulation And Optimization Of A Simultaneous Transmit And Receive Phased Antenna Array Using Adaptive Beamforming And Genetic Algorithm Techniques, Ian Thomas Cummings

Dissertations, Master's Theses and Master's Reports

The development of simultaneous transmit and receive capabilities is on the cutting-edge of research in phased array technology [1, 2, 3]. The large disparity in power between the transmitted and received signals in antenna systems has traditionally prevented operation in a simultaneous mode. However, simultaneous transmit and receive offers great opportunities for increased capabilities and performance in communications, radar, and electronic warfare applications [3]. This technology will be made feasible by realizing a high level of isolation between the transmitted and received signals through a variety of techniques. This work explores the feasibility of choosing non-standard array partitions that--when paired …

A Wireless, Passive Sensor For Measuring Temperature At Orthopedic Implant Sites For Early Diagnosis Of Infections, Salil Sidharthan Karipott

Dissertations, Master's Theses and Master's Reports

Sensorized implants with embedded wireless, passive temperature sensors were developed for early detection of implant-associated infections. The operation principle of the sensor is based on the hypothesis that infections can lead to an increase in local temperature prior to the rise of body temperature. The sensor was an inductive capacitive (LC) circuit that has been used for monitoring of different parameters wirelessly, often in difficult to access environments. The sensor was fabricated on to an interference screw, which is used for tendon and ligament reconstruction surgeries. In this project, a sensorized interference screw was designed and fabricated by accommodating an …

High Performance Multiview Video Coding, Caoyang Jiang

Dissertations, Master's Theses and Master's Reports

Following the standardization of the latest video coding standard High Efficiency Video Coding in 2013, in 2014, multiview extension of HEVC (MV-HEVC) was published and brought significantly better compression performance of around 50% for multiview and 3D videos compared to multiple independent single-view HEVC coding. However, the extremely high computational complexity of MV-HEVC demands significant optimization of the encoder. To tackle this problem, this work investigates the possibilities of using modern parallel computing platforms and tools such as single-instruction-multiple-data (SIMD) instructions, multi-core CPU, massively parallel GPU, and computer cluster to significantly enhance the MVC encoder performance. The aforementioned computing tools …

Design Of Robust Hydrogel Based On Mussel-Inspired Chemistry, Yuan Liu

Dissertations, Master's Theses and Master's Reports

The structure of catechol is found in mussel adhesive proteins and contributed to both wet-resistant adhesion and cohesive curing of these proteins. A synthetic nano-silicate, Laponite was incorporated into catechol-containing hydrogels and the hydrogel network-bound catechol formed strong reversible interfacial interaction with Laponite. The contribution of incorporated catechol-Laponite reversible interfacial interactions to the mechanics of hydrogels constructed by different strategies was studied. In the first strategy, Laponite and catechol were introduced into the double network hydrogel (DN) via the free radical co-polymerization of a catechol-containing monomer, backbone monomer, and crosslinker. The introduction of catechol-Laponite interactions significantly improved the compressive strength …

Design Automation For Carbon Nanotube Circuits Considering Performance And Security Optimization, Lin Liu

Dissertations, Master's Theses and Master's Reports

As prevailing copper interconnect technology advances to its fundamental physical limit, interconnect delay due to ever-increasing wire resistivity has greatly limited the circuit miniaturization. Carbon nanotube (CNT) interconnects have emerged as promising replacement materials for copper interconnects due to their superior conductivity. Buffer insertion for CNT interconnects is capable of improving circuit timing of signal nets with limited buffer deployment. However, due to the imperfection of fabricating long straight CNT, there exist significant unidimensional-spatially correlated variations on the critical CNT geometric parameters such as the diameter and density, which will affect the circuit performance.

This dissertation develops a novel timing …

Implantable Wireless Sensor Networks: Application To Measuring Temperature For In Vivo Detection Of Infections, Praharsh Madappaly Veetil

Dissertations, Master's Theses and Master's Reports

It is has been proven that infection in the body cause a local temperature increase due to localized inflammation. Therefore, a method to provide early diagnostic or long-term tracking of this infection will provide great benefits to patients with diabetic foot ulcers or sickle cell disease, and those receiving hemodialysis where they suffer from a weakened immune system. The goal of this project is to develop an implantable wireless temperature sensor based on a wireless sensor network system for monitoring infections in situ. The analog signals from the thermistors are digitized and wirelessly transmitted to a computer with an ez430-rf2500 …

Impact Of E20 Fuel On A High-Performance, Two-Stroke Engine, Jon Gregory Loesche

Dissertations, Master's Theses and Master's Reports

The purpose of this project was to explore the emissions, combustion, and performance effects of running a gasoline/ethanol fuel mixture of 20 percent by volume (E20) in a fuel-injected, two-stroke engine. The engine was operated at five engine speeds that corresponded with the EPA 5-mode emissions test for snowmobile engines. Single parameter sweeps were conducted along with a preliminary recalibration of the test engine at two E0 target values (lambda and mid-pipe temperature) using E20 fuel.

Baseline testing showed that running E20 fuel produced a leaner air/fuel mixture compared to E0, resulting in higher lambda values for all modes and …

Frontal Crash Analysis Of A Conformable Cng Tank Using Finite Element Analysis, Datta Sandesh Manjunath

Dissertations, Master's Theses and Master's Reports

The purpose of this study is to computationally model and analyze a Conformable Compressed Natural Gas (CNG) fuel tank for frontal crashes using Finite Element Analysis. Researchers have developed a CNG fuel tank, which is conformable, non-conventional and non-cylindrical. This tank increases cost efficiency, volumetric efficiency and cargo efficiency in CNG vehicle applications. A lightweight pickup truck (2015 Chevrolet Silverado) has been used to integrate the CNG tanks and field-testing has been conducted to demonstrate the application.

The report mainly focuses on the effective finite element modeling of the chassis, brackets and tanks using HYPERMESH and RADIOSS. The frontal crash …

Second-Life Battery Electrochemical Impedance Spectroscopy Modeling And Application To A Residential System, Busra Ovali

Dissertations, Master's Theses and Master's Reports

This study presents the modeling of a used hybrid electric vehicle battery (also called second life battery), and its design and simulation for a standalone residential photovoltaic system. For this purpose, the battery was tested through capacity and electrochemical impedance spectroscopy tests (EIS). These tests were done with variable temperatures (0ºC, 15ºC and 30ºC), and results were used to fit an equivalent impedance circuit. This model was used to incorporate a second life battery to a PV system, which was simulated by using daily irradiance and load data for Tucson (AZ) under most various month (May).

Low-Cost Open-Source Gmaw-Based Metal 3-D Printing: Monitoring, Slicer, Optimization, And Applications, Yuenyong Nilsiam

Dissertations, Master's Theses and Master's Reports

Low-cost and open-source gas metal arc welding (GMAW)-based 3-D printing has been demonstrated yet the electrical design and software was not developed enough to enable wide-spread adoption. This thesis provides three novel technical improvements based on the application of mechatronic and software theory that when combined demonstrate the ability for distributed digital manufacturing at the small and medium enterprise scale of steel and aluminum parts. First, low cost metal inert gas welders contain no power monitoring needed to tune GMAW 3-D printers. To obtain this data about power and energy usage during the printing, an integrated monitoring system was developed …

Research And Development Of Industrial Integrated Robotic Workcell And Robotrun Software For Academic Curriculum, Siddharth Y. Parmar

Dissertations, Master's Theses and Master's Reports

Robotic automation is consuming the laborious tasks performed by workers all over industry. The increasing demand for trained robotic engineers to implement and maintain industrial robots has led to the development of various courses in academia. Michigan Tech is a FANUC Authorized Certified Education Training Center for industrial robot training. This report discusses the research and development of an integrated robotic workcell consisting of three Fanuc robots, Allen Bradley programmable logic controller (PLC), Mini-Mover belt conveyor and Fanuc iR-vision system. The workcell allows students to explore an environment similar to industry and intended to be used for laboratory hands-on activities …

Feature And Decision Level Fusion Using Multiple Kernel Learning And Fuzzy Integrals, Anthony Pinar

Dissertations, Master's Theses and Master's Reports

The work collected in this dissertation addresses the problem of data fusion. In other words, this is the problem of making decisions (also known as the problem of classification in the machine learning and statistics communities) when data from multiple sources are available, or when decisions/confidence levels from a panel of decision-makers are accessible. This problem has become increasingly important in recent years, especially with the ever-increasing popularity of autonomous systems outfitted with suites of sensors and the dawn of the ``age of big data.'' While data fusion is a very broad topic, the work in this dissertation considers …

An Optimal Energy Management Strategy For Hybrid Electric Vehicles, Amir Rezaei

Dissertations, Master's Theses and Master's Reports

Hybrid Electric Vehicles (HEVs) are used to overcome the short-range and long charging time problems of purely electric vehicles. HEVs have at least two power sources. Therefore, the Energy Management (EM) strategy for dividing the driver requested power between the available power sources plays an important role in achieving good HEV performance.

This work, proposes a novel real-time EM strategy for HEVs which is named ECMS-CESO. ECMS-CESO is based on the Equivalent Consumption Minimization Strategy (ECMS) and is designed to Catch Energy Saving Opportunities (CESO) while operating the vehicle. ECMS-CESO is an instantaneous optimal controller, i. e., it does not …

Advanced Uses For Carbon Nanotubes: A Spherical Sound Source And Hot-Films As Microphones, Micaela M. Thiery

Dissertations, Master's Theses and Master's Reports

Super-aligned carbon nanotube (CNT) thin-film is used to create thermophones. The thermal properties of CNT film allow it to rapidly heat and cool when supplied AC power producing temperature and pressure gradients and, therefore, audible sound. The advantages of CNT thermophones include eliminating all moving components of traditional speakers and reducing the weight of the speaker itself by using CNT film, which is nearly weightless. Additionally, the flexibility of CNT film provides the unique opportunity to construct loudspeakers of various sizes and geometries. In this work, a spherical CNT thermophone is designed, manufactured, and tested for directivity with the overall …

Computational Ultrasound Elastography: A Feasibility Study, Yu Wang

Dissertations, Master's Theses and Master's Reports

Ultrasound Elastography (UE) is an emerging set of imaging modalities used to assess the biomechanical properties of soft tissues. UE has been applied to numerous clinical applications. Particularly, results from clinical trials of UE in breast lesion differentiation and staging liver fibrosis indicated that there was a lack of confidence in UE measurements or image interpretation. Confidence on UE measurements interpretation is critically important for improving the clinical utility of UE. The primary objective of my thesis is to develop a computational simulation platform based on open-source software packages including Field II, VTK, FEBio and Tetgen. The proposed virtual simulation …

Characterization Of Ecological Water Stress In The U.S. Great Lakes Region Using A Geospatial Modeling Approach, Sara Alian

Dissertations, Master's Theses and Master's Reports

Anthropocentric water resources management affects aquatic habitats by changing streamflow regime. Understanding the impacts of water withdrawal from different sources and consumption by various economic sectors at different spatial and temporal scales is key to characterizing ecologically harmful streamflow disturbances. To this end, we developed a generic, integrative framework to characterize catchment scale water stress at annual and monthly time scales. The framework accounts for spatially cumulative consumptive and non-consumptive use impacts and associated changes in flow due to depletion and return flow along the stream network. Application of the framework to the U.S. Great Lakes Region indicates that a …

Accuracy Assessment Of 3d Point Clouds Generated By Photogrammetry From Different Distances, Zhongming An

Dissertations, Master's Theses and Master's Reports

Photogrammetry is playing more important role in many industries today, and thanks to Structure-from-Motion, 3D point clouds and 3D meshes can be produced and be used as a resource for surveying and documentation.

In this project, the accuracies of Structure-from-Motion generated point clouds from pictures taken from different distances are assessed to determine if the distance has a significant impact on the accuracy and what kind of pattern the accuracies will show if there is any. Due to space limit, an improvised turntable was used in order to mimic the condition where camera moves around the object. Multiple images were …

Electro-Optic Contact Poling Of Polymer Waveguide Devices And Thin Films, Michael Briseno

Dissertations, Master's Theses and Master's Reports

Optical communication is a high speed, large bandwidth, low cost, and power efficient method of transferring data over short-haul and long-haul channels. Optical communication requires devices (optical modulators) that utilize the originating electrical signal information to modulate a corresponding optical signal. State of the art optical modulators can be used for communicating signals at modulation frequencies up to 100 GHz and faster. Polymer modulators are used over lithium niobate due to the large potential electro-optic coefficient, which has been shown to be as high as 226 pm/V in thin films.

Organic electro-optic polymers used in thin film modulators contain nonlinear …

Development Of A High-Fidelity Model And Kalman Filter Based State Estimator For Simulation And Control Of Nox Reduction Performance Of A Scr Catalyst On A Dpf, Venkata Rajesh Chundru

Dissertations, Master's Theses and Master's Reports

Reduction of emissions and improving the fuel consumption are two prime research areas in Diesel engine development. The present after-treatment systems being used for emissions control include diesel oxidation catalyst (DOC) for NO, HC and CO oxidation along with catalyzed particulate filters for PM (particulate matter) and selective catalytic reduction (SCR) for controlling NOx emissions. Recently an after-treatment system called SCR catalyst on a DPF capable of simultaneously reducing both NOx and PM emissions has been developed in order to reduce the overall size of the after-treatment system.

The goal of this proposed research is to create a state estimator …

Heterogeneous Multi-Sensor Fusion For 2d And 3d Pose Estimation, Hanieh Deilamsalehy

Dissertations, Master's Theses and Master's Reports

Sensor fusion is a process in which data from different sensors is combined to acquire an output that cannot be obtained from individual sensors. This dissertation first considers a 2D image level real world problem from rail industry and proposes a novel solution using sensor fusion, then proceeds further to the more complicated 3D problem of multi sensor fusion for UAV pose estimation.

One of the most important safety-related tasks in the rail industry is an early detection of defective rolling stock components. Railway wheels and wheel bearings are two components prone to damage due to their interactions with the …

Performance Of Hard Disk Drives In High Noise Environments, Trinoy Dutta

Dissertations, Master's Theses and Master's Reports

Digital information stored in rotational media, such as Hard Disk Drives (HDD) needs to be reliable and readily accessible. Various studies have been performed on the modal analysis of HDDs and the noise emitted during operation. Analysis performed by Siemens Corporation, IBM and Tyco Fire Protection Products show that HDDs are sensitive to noise. This report initially focusses on identifying the critical frequency ranges and the levels of noise where the performance of the drives reduces. A series of tests have been performed using pink noise at one-third octave frequency bands at sound pressure levels ranging from 80 dB to …