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Articles 88021 - 88050 of 197093

Full-Text Articles in Engineering

Avoiding Bus Bunching: From Theory To Practice, Ricardo Giesen Jan 2017

Avoiding Bus Bunching: From Theory To Practice, Ricardo Giesen

PSU Transportation Seminars

The problem of bus bunching in a high frequency service has been largely studied in the literature.

This phenomenon is produced by three main factors

(i) the variability in travel time between stops; (ii) variations in passenger demand; and (iii) drivers’ heterogeneity.

In order to tackle this phenomenon a wide range of control strategies have been proposed, however, none of them had been successfully implemented on a large transit network with high frequency services.

In this talk, we present a control scheme based on a rolling horizon optimization problem that has been successfully implemented for real-time control of two high …


A Well Clear Recommendation For Small Uas In High-Density, Ads-B-Enabled Airspace, Timothy Mclain, Matthew O. Duffield Jan 2017

A Well Clear Recommendation For Small Uas In High-Density, Ads-B-Enabled Airspace, Timothy Mclain, Matthew O. Duffield

Faculty Publications

With the growing popularity of small unmanned aircraft systems (UAS), there is a significant need to enable small UAS to detect and avoid collisions with both manned and unmanned aircraft. The capabilities of ADS-B make it an attractive sensor for detect and avoid (DAA), but it is susceptible to frequency congestion. This paper quantitatively analyzes the frequency limitations of 978 MHz ADS-B. It then uses these limitations to make a recommendation for well clear in ADS-B-equipped airspace that has a high density of small UAS operations.


Hyperbolic Metamaterials-Based Plasmonic Biosensor For Fluid Biopsy With Single Molecule Sensitivity, Kandammathe Valiyaveedu Sreekanth, Mohamed Elkabbash, Yunus Alapan, Efe Ilker Ilker, Michael Hinczewski, Umut A. Gurkan, Giuseppe Strangi Jan 2017

Hyperbolic Metamaterials-Based Plasmonic Biosensor For Fluid Biopsy With Single Molecule Sensitivity, Kandammathe Valiyaveedu Sreekanth, Mohamed Elkabbash, Yunus Alapan, Efe Ilker Ilker, Michael Hinczewski, Umut A. Gurkan, Giuseppe Strangi

Faculty Scholarship

Plasmonic sensors are one of the most powerful optical biosensors, which can be used for the detection of small numbers of molecules at ultra-low concentrations. However, the detection of dilute analytes of low molecular weight (Da) is still a challenging task using currently available plasmonic biosensors. Here, we demonstrate the detection of both lower and heavier molecular weight biomolecules close to single molecule level using a novel plasmonic biosensor platform based on hyperbolic metamaterials. We show experimentally the extraordinary spectral and angular sensitivities of the biosensor platform, from visible to near infrared (NIR) wavelengths, by exciting the bulk plasmon polaritons …


Effect Of Liquid Contamination On Hermeticity And Seal Strength Of Flexible Pouches With Lldpe, Francesca Delle Cese, Koushik Saha, S. Roy, Jay Singh Jan 2017

Effect Of Liquid Contamination On Hermeticity And Seal Strength Of Flexible Pouches With Lldpe, Francesca Delle Cese, Koushik Saha, S. Roy, Jay Singh

Journal of Applied Packaging Research

Flexible packaging is a growing successful market and the majority of flexible package applications are for the food industry. The demand for process optimization and reduced production costs, has led to an increase in flexible packaging. However, fast production lines can result in contamination in the seal area. For flexible food packaging, contamination is considered any food particle or substance trapped in the seal area. Current quality control processes can detect contamination in the seal area, but it is not determined if seal contamination affects seal quality. Oil-based and sodium based snack foods are two common categories that can be …


Producing Food Packaging Printing Ink Via Green Emulsion Aggregation Method, Maryam Ataeefard, Shohre Rouhani Jan 2017

Producing Food Packaging Printing Ink Via Green Emulsion Aggregation Method, Maryam Ataeefard, Shohre Rouhani

Journal of Applied Packaging Research

Digital printing will become more and more important in the packaging industry. Digital printing technology is growing because it allows the print suppliers to improve the level of service they offering to their customers, as well as, it opens new opportunities and helps them to make more money. Additives, dyestuffs, resin and other chemicals in packaging printing ink may influence safety of the food. Therefore, choosing suitable materials are very important in food packing ink. Over the last years, many printing ink manufacturers moved toward more sustainable inks. Drivers for this development, besides the resource scarcity and a higher legislative …


The Effect Of Creasing Lines On The Compression Strength Of Adjustable Height Corrugated Boxes, Péter Csavajda, Péter Böröcz, Ákos Mojzes, Bence Molnár Jan 2017

The Effect Of Creasing Lines On The Compression Strength Of Adjustable Height Corrugated Boxes, Péter Csavajda, Péter Böröcz, Ákos Mojzes, Bence Molnár

Journal of Applied Packaging Research

Due to its high strength and low density, the corrugated fibreboard (CFB) box is one of the most popular types of packaging all over the world. This packaging device is able to fulfil a huge number of requirements of the logistic process, during the phases of handling, shipping and storage. In addition to this, corrugated packaging is easily machinable, so it is also suitable for special supply chains and products. These special needs include the requirement to fit to the inner measurements of the shipping device, e.g. the shipping container. This is particularly expected in case of less than container-load …


Adding A Polymer Film Barrier Layer In The Press Forming Process Of Paperboard Trays, Ville Leminen, Panu Tanninen, Mika Kainusalmi, Kirubel Bogale, Juha Varis Jan 2017

Adding A Polymer Film Barrier Layer In The Press Forming Process Of Paperboard Trays, Ville Leminen, Panu Tanninen, Mika Kainusalmi, Kirubel Bogale, Juha Varis

Journal of Applied Packaging Research

The aim of this paper was to investigate the possibility to add a barrier layer in the press forming phase of paperboard trays by sealing a polymer film to a paperboard substrate. Plastic coating is often an important part of packages manufactured for food packaging. Traditionally the paperboards for food packaging are coated in the paper mill before the actual forming of the package. Experiments with coated and uncoated boards were made and the bonding and adhesion of materials was observed. The results indicate that adhesion between the board and the film can be achieved in the forming process. However …


The Effect Of Graphene On Catalytic Performance Of Palladium Nanoparticles Decorated With Fe3o4, Co3o4, And Ni (Oh)2: Potential Efficient Catalysts Used For Suzuki Cross—Coupling, Hany A. Elazab Dr Jan 2017

The Effect Of Graphene On Catalytic Performance Of Palladium Nanoparticles Decorated With Fe3o4, Co3o4, And Ni (Oh)2: Potential Efficient Catalysts Used For Suzuki Cross—Coupling, Hany A. Elazab Dr

Chemical Engineering

In this research, we report a scientific investigation of an efficient method used for the synthesis of highly active Palladium Nanoparticles decorated with Fe3O4, Co3O4, and Ni (OH)2 Supported on Graphene as Potential Efficient Catalysts for Suzuki Cross—Coupling. Pd/Fe3O4 nanoparticles supported on graphene nanosheets (Pd/ Fe3O4/G) showed an excellent catalytic activity for Suzuki coupling reactions and recycled for up to four times without loss of catalytic activity. An efficient magnetic catalyst has been successfully synthesized using a simple, reproducible fast and reliable method using microwave irradiation conditions. The prepared catalysts are magnetic as in case of iron and cobalt oxides …


Image And Information Fusion Experiments With A Software-Defined Multi-Spectral Imaging System For Aviation And Marine Sensor Networks, Sam B. Siewert, Matthew Demi Vis, Ryan Claus, Ramnarayan Krishnamurthy, Surjith B. Singh, Akshay K. Singh, Shivasankar Gunasekaran Jan 2017

Image And Information Fusion Experiments With A Software-Defined Multi-Spectral Imaging System For Aviation And Marine Sensor Networks, Sam B. Siewert, Matthew Demi Vis, Ryan Claus, Ramnarayan Krishnamurthy, Surjith B. Singh, Akshay K. Singh, Shivasankar Gunasekaran

Publications

The availability of Internet, line-of-sight and satellite identification and surveillance information as well as low-power, low-cost embedded systems-on-a-chip and a wide range of visible to long-wave infrared cameras prompted Embry Riddle Aeronautical University to collaborate with the University of Alaska Arctic Domain Awareness Center (ADAC) in summer 2016 to prototype a camera system we call the SDMSI (Software-Defined Multi-spectral Imager). The concept for the camera system from the start has been to build a sensor node that is drop-in-place for simple roof, marine, pole-mount, or buoy-mounts. After several years of component testing, the integrated SDMSI is now being tested, first …


Quality Improvement In Drilling Silicon By Using Micro Laser Assisted Drilling, Barkin Bakir Jan 2017

Quality Improvement In Drilling Silicon By Using Micro Laser Assisted Drilling, Barkin Bakir

The Hilltop Review

The micro-laser assisted drilling (µ-LAD) of monocrystalline silicon (100), using a diamond cutting tool coupled with a laser, was tested in order to improve the cutting edge quality of a drilled samples. The laser beam is transmitted through an optically transparent diamond drill bit and focused precisely at the tool-workpiece interface, where the material is under high pressure induced by the diamond tool. The influence of the laser power on the quality and the inner surface finish of the drilled materials is investigated. Different laser powers were used to carry out the experiments. The experimental results indicated that the µ-LAD …


Disciplinary Differences In Out-Of-School High School Science Experiences And Influence On Students’ Engineering Choices, Allison Godwin, Gerhard Sonnert, Philip M. Sadler Jan 2017

Disciplinary Differences In Out-Of-School High School Science Experiences And Influence On Students’ Engineering Choices, Allison Godwin, Gerhard Sonnert, Philip M. Sadler

Journal of Pre-College Engineering Education Research (J-PEER)

Participation from a variety of students is important to the long-term growth of the engineering field. Much of the research on engineering recruitment or career choice has focused on engineering as a whole, even though engineering disciplines are varied in student participation and focus. This work examines how students’ out-of-school interests and experiences in high school predict the likelihood of choosing a career in a particular engineering discipline. Out-of-school experiences offer more unstructured ways for students to meaningfully engage with science and engineering outside of the confines of the classroom. These experiences offer opportunities to spark particular science interests not …


2012, May - San Luis Obispo County Master Water Report, Volume I Of Iii Jan 2017

2012, May - San Luis Obispo County Master Water Report, Volume I Of Iii

San Luis Obispo Public Works Water Reports

A compilation of current and future water resource management activities with in San Luis Obispo County that are organized by Water Planning Areas. The report explores how the activities interrelate, analyzes current and future supplies and demands, and identifies future water management strategies and ways to optimize existing strategies.


2012, May - San Luis Obispo County Master Water Report, Volume Ii Of Iii Jan 2017

2012, May - San Luis Obispo County Master Water Report, Volume Ii Of Iii

San Luis Obispo Public Works Water Reports

A compilation of current and future water resource management activities with in San Luis Obispo County that are organized by Water Planning Areas. The report explores how the activities interrelate, analyzes current and future supplies and demands, and identifies future water management strategies and ways to optimize existing strategies.


Effects Of Rejuvenators On High-Rap Mixtures Based On Laboratory Tests Of Asphalt Concrete Mixtures And Fine Aggregate Matrix Mixtures, Hesamaddin Nabizadeh, Hamzeh Haghshenas, Yong-Rak Kim, F. T. S. Aragão Jan 2017

Effects Of Rejuvenators On High-Rap Mixtures Based On Laboratory Tests Of Asphalt Concrete Mixtures And Fine Aggregate Matrix Mixtures, Hesamaddin Nabizadeh, Hamzeh Haghshenas, Yong-Rak Kim, F. T. S. Aragão

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

Although the linear viscoelastic stiffness, fracture characteristics, and permanent deformation behavior of AC mixtures can be determined through experiments, it is generally time-consuming and expensive to reach statistically repeatable results. Thus, it is attractive to pursue alternative methods that are cheaper, faster, and repeatable in order to efficiently evaluate and predict asphalt mixtures’ core mechanical characteristics (such as stiffness, fatigue, and plastic deformation).


Chemical–Rheological Evaluation Of The Short-Term And Long-Term Effectiveness Of Binder Rejuvenators, H. F. Haghshenas, S. Kommidi, D. Nguyen, Yong-Rak Kim Jan 2017

Chemical–Rheological Evaluation Of The Short-Term And Long-Term Effectiveness Of Binder Rejuvenators, H. F. Haghshenas, S. Kommidi, D. Nguyen, Yong-Rak Kim

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

Many previous studies have investigated how rejuvenators affect/alter mechanical/chemical characteristics of aged binders. However, it has not been actively examined how the rejuvenated binders will perform for the next round of service after the rejuvenation was made. A better understanding of the short-term and long-term effect of rejuvenating agents in RAP blended asphalt mixtures is necessary to achieve more appropriate selection and use of rejuvenating agents.


Evaluation Of Thin Asphalt Overlay Pavement Preservation In Nebraska: Laboratory Tests, Mepdg, And Lcca (17-2624), Soohyok Im, Taesun You, Yong-Rak Kim, Gabriel Nsengiyumva, Robert Rea, Hamzeh Haghshenas Jan 2017

Evaluation Of Thin Asphalt Overlay Pavement Preservation In Nebraska: Laboratory Tests, Mepdg, And Lcca (17-2624), Soohyok Im, Taesun You, Yong-Rak Kim, Gabriel Nsengiyumva, Robert Rea, Hamzeh Haghshenas

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

Thin asphalt overlays offer an economical resurfacing, preservation, and renewal paving solution for roads that require safety and smoothness improvements. Recently, thin asphalt overlays have been used in Nebraska as a promising pavement preservation technique that needs evaluations.


The Irreversible Momentum Of Clean Energy, Barack Obama Jan 2017

The Irreversible Momentum Of Clean Energy, Barack Obama

United States Department of Energy: Publications

The release of carbon dioxide (CO2) and other greenhouse gases (GHGs) due to human activity is increasing global average surface air temperatures, disrupting weather patterns, and acidifying the ocean. Left unchecked, the continued growth of GHG emissions could cause global average temperatures to increase by another 4°C or more by 2100 and by 1.5 to 2 times as much in many midcontinent and far northern locations. Although our understanding of the impacts of climate change is increasingly and disturbingly clear, there is still debate about the proper course for U.S. policy—a debate that is very much on display …


Development Of Earthquake Vulnerability Functions And Risk Curves For Low And Mid-Rise Hotel Buildings Using A Performance-Based Loss Estimation Framework, Amir Safiey, Weichiang Pang, Mohammad Javanbarg, Keivan Rokneddin, Ershad Ziaei Jan 2017

Development Of Earthquake Vulnerability Functions And Risk Curves For Low And Mid-Rise Hotel Buildings Using A Performance-Based Loss Estimation Framework, Amir Safiey, Weichiang Pang, Mohammad Javanbarg, Keivan Rokneddin, Ershad Ziaei

Publications

The concept of performance-based earthquake engineering has gained significant attentions in both the research and engineering communities. The development of a performance-based seismic loss assessment framework, known as the FEMA P-58 method, allows one to estimate the potential financial losses of a building using performance-based engineering method. This research employs a seismic loss estimation framework derived using the P-58 method to estimate the monetary loss of a mid-rise wood-frame hotel building which is assumed to be located in Napa Valley, California. A 3D structural model representative of the dynamic behavior of the wood-frame hotel was created and subjected to Incremental …


Analytical Content Vulnerability Assessment Methodology For Earthquake Catastrophe Models, Keivan Rokneddin, Amir Safiey, Mohammad Javanbarg, Vijay Manghnani, Weichiang Pang Jan 2017

Analytical Content Vulnerability Assessment Methodology For Earthquake Catastrophe Models, Keivan Rokneddin, Amir Safiey, Mohammad Javanbarg, Vijay Manghnani, Weichiang Pang

Publications

The scarcity of detailed claims data for building contents (Coverage C) from historical earthquake events poses a significant challenge for property insurance catastrophe models to reliably estimate the losses associated to building contents. To develop content vulnerability functions empirically, one would need to have access to data from a multitude of historical events; however, loss disaggregation by coverage is rarely reported even when claims data become available from recent significant events such as Maule (2010) and Tohoku (2011). While damage to the building structure (Coverage A) can be estimated analytically using simulation-based fragility functions to amend sparse historical observations, the …


Estimating Airport Operations At General Aviation Airports Using The Faa Npias Airport Categories, Mary E. Johnson, Yue Gu Jan 2017

Estimating Airport Operations At General Aviation Airports Using The Faa Npias Airport Categories, Mary E. Johnson, Yue Gu

International Journal of Aviation, Aeronautics, and Aerospace

The number of annual aircraft operations (take-offs and landings) is a significant concern to both airport owners and operators and to governmental agencies because operations data are one of the most important criteria used for determining future investments in airports. However, estimating the number of aircraft operations at non-towered general aviation airports is challenging work due to the lack of counts from air traffic control towers or useful estimates developed using models. Previous work in estimating annual aircraft operations has resulted in models and sampling methods that are imprecise or difficult to use. In 2014, new classification categories of 2,939 …


Assessing Dprestin & Nadc1 (Indy) Interaction On Calcium Oxalate Crystal Formation In A Drosophila Model Of Kidney Stones, Jessica Lin Jan 2017

Assessing Dprestin & Nadc1 (Indy) Interaction On Calcium Oxalate Crystal Formation In A Drosophila Model Of Kidney Stones, Jessica Lin

Undergraduate Research Symposium Posters

Calcium oxalate (CaOx) accounts for >70%of kidney stones, yet why CaOx stones form is poorly understood. While several factors contribute to the stone aggregation and growth, elucidating the roles of oxalate transporters can help demystify this phenomenon. Using a Drosophila model to study the formation and inhibition of CaOx crystals in the fly Malpighian tubule (MT), oxalate transport via dPrestin—the fly Slc26a6 Cl-/Ox2- exchanger was studied using both electrophysiology and MT dissection with CaOx birefringence assays. Here, the fly model suffices as it recapitulates renal oxalate excretion. Additionally, the mammalian dicarboxylate transporter NaDC1 (Indy in Drosophila) …


Interplay Of Composition, Structure, And Electron Density Of States In W-Os Cathode Materials And Relationship With Thermionic Emission, Qunfei Zhou, Thomas John Balk, Matthew J. Beck Jan 2017

Interplay Of Composition, Structure, And Electron Density Of States In W-Os Cathode Materials And Relationship With Thermionic Emission, Qunfei Zhou, Thomas John Balk, Matthew J. Beck

Chemical and Materials Engineering Faculty Publications

The presence and composition of W-Os alloys have been found to significantly affect the thermionic emission properties of Os-coated tungsten dispenser cathodes. However, the comprehensive understanding of structure–property relationships needed to design improved tungsten cathodes with larger thermionic emission is still lacking. In this study, composition–structure–property relationships governing thermionic emission from W-Os alloys were investigated using quantum mechanical calculations. Low-energy W-Os atomic configurations at various compositions were determined from first-principles calculations based on density functional theory in combination with cluster expansion calculations. Electronic properties were investigated in terms of the electron density of states. The relative position of the Fermi …


Rans Simulations Of Aerodynamic Performance Of Naca 0015 Flapped Airfoil, Sohaib Obeid, Ratneshwar Jha, Goodarz Ahmadi Jan 2017

Rans Simulations Of Aerodynamic Performance Of Naca 0015 Flapped Airfoil, Sohaib Obeid, Ratneshwar Jha, Goodarz Ahmadi

Henry M. Rowan College of Engineering Departmental Research

An analysis of 2D subsonic flow over an NACA 0015 airfoil with a 30% trailing edge flap at a constant Reynolds number of 106 for various incidence angles and a range of flap deflections is presented. The steady-state governing equations of continuity and momentum conservation are solved combined with the realizable k-ε turbulence model using the ANSYS-Fluent code (Version 13.7, ANSYS, Inc., Canonsburg, PA, USA). The primary objective of the study is to provide a comprehensive understanding of flow characteristics around the NACA 0015 airfoil as a function of the angle of attack and flap deflection at Re = 106 …


Multi-Stage Nozzle-Shape Optimization For Pulsed Hydrogen-Air Detonation Combustor, Francesco Ornano, James Braun, Bayindir H. Saracoglu, Guillermo Paniagua Jan 2017

Multi-Stage Nozzle-Shape Optimization For Pulsed Hydrogen-Air Detonation Combustor, Francesco Ornano, James Braun, Bayindir H. Saracoglu, Guillermo Paniagua

School of Aeronautics and Astronautics Faculty Publications

hermal engines based on pressure gain combustion offer new opportunities to generate thrust with enhanced efficiency and relatively simple machinery. The sudden expansion of detonation products from a single-opening tube yields thrust, although this is suboptimal. In this article, we present the complete design optimization strategy for nozzles exposed to detonation pulses, combining unsteady Reynolds-averaged Navier-Stokes solvers with the accurate modeling of the combustion process. The parameterized shape of the nozzle is optimized using a differential evolution algorithm to maxi­ mize the force at the nozzle exhaust. The design of experiments begins with a first optimization considering steady-flow conditions, subsequently …


Factors Associated With Crash Severities In Built-Up Areas Along Rural Highways Of Nevada: A Case Study Of 11 Towns, P P. Shrestha, K J. Shrestha Jan 2017

Factors Associated With Crash Severities In Built-Up Areas Along Rural Highways Of Nevada: A Case Study Of 11 Towns, P P. Shrestha, K J. Shrestha

Civil and Environmental Engineering and Construction Faculty Research

In 2014, 32,675 deaths were recorded in vehicle crashes within the United States. Out of these, 51% of the fatalities occurred in rural highways compared to 49% in urban highways. No specific crash data are available for the built-up areas along rural highways. Due to high fatalities in rural highways, it is important to identify the factors that cause the vehicle crashes. The main objective of this study is to determine the factors associated with severities of crashes that occurred in built-up areas along the rural highways of Nevada. Those factors could aid in making informed decisions while setting up …


Survey Of Value Assessment Programs Within Transportation Construction Projects In U.S, Rafaa Khalifa, Robert Stewart Jan 2017

Survey Of Value Assessment Programs Within Transportation Construction Projects In U.S, Rafaa Khalifa, Robert Stewart

Engineering and Technology Management Faculty Publications and Presentations

In order to deliver transportation project on time and within budget, project planners and decision makers need to understand the desirable outcomes of projects or programs to make intelligent decisions. In addition, they also need effective tools and techniques to guide those decisions. In development of a guide that identifies available tools and techniques to foster useable and improved practices for key stakeholders of transportation projects, this paper as a preliminary study assessed current utilization of project delivery value improvement programs such as value engineering (VE), risk analysis/management (RA/RM) and constructability reviews (CR) for transportation projects. To determine whether states …


Electrical & Computer Engineering News, Georgia Southern University Jan 2017

Electrical & Computer Engineering News, Georgia Southern University

Electrical & Computer Engineering: News & Publications (2014-2023)

  • Antennas and Wireless Propagation (AWP) Lab Present Research at Colloquium


Idiosyncratic Drug-Induced Liver Injury (Idili): Potential Mechanisms And Predictive Assays, Alexander D. Roth, Moo-Yeal Lee Jan 2017

Idiosyncratic Drug-Induced Liver Injury (Idili): Potential Mechanisms And Predictive Assays, Alexander D. Roth, Moo-Yeal Lee

Chemical & Biomedical Engineering Faculty Publications

Idiosyncratic drug-induced liver injury (IDILI) is a significant source of drug recall and acute liver failure (ALF) in the United States. While current drug development processes emphasize general toxicity and drug metabolizing enzyme- (DME-) mediated toxicity, it has been challenging to develop comprehensive models for assessing complete idiosyncratic potential. In this review, we describe the enzymes and proteins that contain polymorphisms believed to contribute to IDILI, including ones that affect phase I and phase II metabolism, antioxidant enzymes, drug transporters, inflammation, and human leukocyte antigen (HLA). We then describe the various assays that have been developed to detect individual reactions …


Dirichlet Process Gaussian Mixture Models For Real-Time Monitoring And Their Application To Chemical Mechanical Planarization, Jia (Peter) Liu, Omer F. Beyca, Prahalad K. Rao, Zhenyu (James) Kong, Satish T. S. Bukkapatnam Jan 2017

Dirichlet Process Gaussian Mixture Models For Real-Time Monitoring And Their Application To Chemical Mechanical Planarization, Jia (Peter) Liu, Omer F. Beyca, Prahalad K. Rao, Zhenyu (James) Kong, Satish T. S. Bukkapatnam

Department of Mechanical and Materials Engineering: Faculty Publications

The goal of this work is to use sensor data for online detection and identification of process anomalies (faults). In pursuit of this goal, we propose Dirichlet process Gaussian mixture (DPGM) models. The proposed DPGM models have two novel outcomes: 1) DP-based statistical process control (SPC) chart for anomaly detection and 2) unsupervised recurrent hierarchical DP clustering model for identification of specific process anomalies. The presented DPGM models are validated using numerical simulation studies as well as wireless vibration signals acquired from an experimental semiconductor chemical mechanical planarization (CMP) test bed. Through these numerically simulated and experimental sensor data, we …


Inhibition Of Mammalian Glycoprotein Ykl-40 Identification Of The Physiological Ligand, Abhishek A. Kognole, Christina M. Payne Jan 2017

Inhibition Of Mammalian Glycoprotein Ykl-40 Identification Of The Physiological Ligand, Abhishek A. Kognole, Christina M. Payne

Chemical and Materials Engineering Faculty Publications

YKL-40 is a mammalian glycoprotein associated with progression, severity, and prognosis of chronic inflammatory diseases and a multitude of cancers. Despite this well documented association, identification of the lectin′s physiological ligand and, accordingly, biological function has proven experimentally difficult. YKL-40 has been shown to bind chito-oligosaccharides; however, the production of chitin by the human body has not yet been documented. Possible alternative ligands include proteoglycans, polysaccharides, and fibers like collagen, all of which makeup the extracellular matrix. It is likely that YKL-40 is interacting with these alternative polysaccharides or proteins within the body, extending its function to cell biological roles …