Engineering Commons^™

Rebuilding Kidneys, Alonzo D. Cook, Deverly L. Roeder, Jonathan J. Wisco

Journal of Undergraduate Research

The motivation for this work was the tremendous need for replacement kidneys. End-stage renal disease (ESRD) affects over 500,000 patients in the U.S. and costs Medicare $30 Billion annually for dialysis and transplant procedures. Our overall objective was to engineer kidneys from decellularized porcine extracellular matrix (DPECM) scaffolds and cell cultures grown from human progenitor cells. The primary reason for using human cells was to develop non-immunogenic kidneys that can be used to treat the more than 100,000 chronic kidney disease (CKD) patients awaiting a transplant, thus obviating the need for post-transplant immunosuppressive therapy and the associated risks of acute …

Validation Of Adaptive Control Laws Using Optimization And Trajectory Sensitivity, Mario Luca Fravolini, Antonio Ficola, Fabio Radicioni, Tansel Yucelen, Ehsan Arabi

Mechanical and Aerospace Engineering Faculty Research & Creative Works

In this paper it is proposed an easy-to-use verification and validation method for adaptive control laws that relies on time domain simulations. The problem is set as a trajectory falsification problem that is the search of closed loop trajectories that, starting from a set of admissible initial conditions, reach a set of unsafe states. The falsification is placed as a nonlinear optimization problem whose decision variables are the initial condition of the states and the uncertain parameters of the system. The falsification is performed iteratively using the local gradient of the sensitivity function derived from a linearized model of the …

A Decentralized Adaptive Control Architecture For Large-Scale Active-Passive Modular Systems, Benjamin C. Gruenwald, Ehsan Arabi, Tansel Yucelen, Animesh Chakravarthy, Drew Mcneely

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Decentralized control of large-scale active-passive modular systems is considered. These systems consist of physically interconnected and generally heterogeneous modules, where local control signals can be only applied to a subset of these modules (i.e., active modules) and the rest are not subject to any control signals (i.e., passive modules). Using a set-theoretic adaptive control approach predicated on restricted potential functions, we design decentralized command following control architectures for each active module such that they can effectively perform their tasks with strict performance guarantees in the presence of unknown physical interconnections between modules and module-level system uncertainties. The efficacy of the …

An Algorithm For Enlarging The Region Of Attraction Using Trajectory Reversing, Nilay Kant, Dhrubajit Chowdhury, Ranjan Mukherjee, Hassan K. Khalil

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Trajectory reversing is a method commonly used for estimating the region of attraction of stabilized equilibria. Using a discrete set of points obtained by trajectory reversing, this paper presents an algorithm for estimation and mathematical representation of the region of attraction using convex hulls. Several two-dimensional examples are presented to illustrate the usefulness of the algorithm. The method provides larger estimates compared to that obtained by existing algorithms, but its main advantage lies in its applicability to higher-order systems. The mathematical representation of the region of attraction is useful in applying the Impulse Manifold Method, which was developed for stabilization …

Enlarging The Region Of Attraction Of Equilibria Of Underactuated Systems Using Sum Of Squares And Impulse Manifold Method, Dhrubajit Chowdhury, Nilay Kant, Ranjan Mukherjee, Hassan K. Khalil

Mechanical and Aerospace Engineering Faculty Research & Creative Works

This paper presents an algorithm to enlarge the estimate of the Region of Attraction of stable equilibria of underactuated systems. To achieve this, we use a combination of the Sum of Squares (SOS) method and the Impulse Manifold Method (IMM). Initially, the SOS method is used to optimize the control input u(x) in order to obtain an enlarged Region of Attraction. The IMM is then applied on enlarged Region of Attraction obtained using SOS to further enlarge it. The IMM is implemented using high gain feedback and to demonstrate the efficacy of our algorithm, we present simulation results where an …

Space-Time Transportation System Modelling: From Traveler’S Characteristics To The Network Design Problem, Mohsen Parsafard

USF Tampa Graduate Theses and Dissertations

Traditional network design problems only consider the long-term stationary travel patterns (e.g., fixed OD demand) and short-term variations of human mobility are ignored. This study aims to integrate human mobility characteristics and travel patterns into network design problems using a space-time network structure. Emerging technologies such as location-based social network platforms provide a unique opportunity for understanding human mobility patterns that can lead to advanced modeling techniques. To reach our goal, at first multimodal network design problems are investigated by considering safety and flow interactions between different modes of transport. We develop a network reconstruction method to expand a single-modal …

Loss Model For Gallium Nitride Dc-Dc Buck Converter, Rushi P. Patel

Pursuit - The Journal of Undergraduate Research at The University of Tennessee

In recent years, more research has been done on Enhancement Mode Gallium Nitride (eGaN) converters, as the world is moving towards more power efficient converters. Power converters play a major role in efficiently controlling and converting electric energy used by machines, systems, and everyday products. The process to make converters more efficient was complicated and slow in the twentieth century. One of the important aspects in power electronics is to evaluate different losses and minimize losses to achieve high efficiency of the converter. With help of simulation tools such as MATLAB and LTspice, this process has become much faster and …

Evaluation Of Foldable Tractor Roll-Over Protective Structures (Rops) Clearance, Luke Martin

Pursuit - The Journal of Undergraduate Research at The University of Tennessee

Tractor rollovers are a leading cause of death in the agricultural industry. While rollovers continue to happen, Roll-Over Protective Structures (ROPS) have shown great ability to prevent or reduce the casualties and injuries associated with rollover events. One authority on the subject even goes so far as to claim that “that fatality rates due to tractor overturns could be reduced by a minimum of 71% if all tractors in the U.S. were equipped with ROPS,” (NIOSH, 2009). The potential of this promising statistic has been devalued slightly due to the misapplication of foldable ROPS by leaving the ROPS in the …

Streambank Erosion Mapping On The Nottoway River Using Gps-Based Above-Water Video, Emine Fidan

Pursuit - The Journal of Undergraduate Research at The University of Tennessee

This project concerns the development of streambank erosion maps on military installations utilizing GPS-based above-water video mapping and image georeferencing techniques. The river mapped was the Nottoway River at the Fort Pickett military installation on October 10-11, 2015. Kayak-mounted above-water cameras were utilized to capture georeferenced images of streambank erosion. These GIS-based erosion classifications were utilized to develop erosion maps for determining streambank erosion conditions along the river. Areas of high erosion were identified as about two percent of the river (2167 ft. of streambank length). These maps allow for the opportunity to revisit the sites to determine changes in …

Identification Of Key Drivers For Municipal Utility Performance, Jasmin Alsaied

Pursuit - The Journal of Undergraduate Research at The University of Tennessee

This report explores the various performance indicators for municipal electric utilities and the greatest impact financial investments can make for improving these indicators. A literature search provided key detail about performing an analysis that would prove useful to utilities. The analysis identifies key performance indicators that allowed for the most prudent of investments. Data mining techniques and statistical analyses were performed on data sets concerning the 51 North Carolina municipal electric utilities to identify several key ratios and performance indicators that have the greatest impact on cost of service, system reliability, and customer satisfaction. Statistical analyses were used to determine …

Comparing Building Modeling Software To The Energy Record Of A Preexisting Structure, Nathan Lasley

Mahurin Honors College Capstone Experience/Thesis Projects

Buildings are complex systems - even "simple" residential structures. Many factors go into building energy consumption and the design to reduce it. Computer energy modeling allows the simultaneous consideration and balance of many of those variables. Computer models are only as good as the information provided however. Tools like blower door and duct blaster can be used to aid in verifying the model or to provide more information to build a better model. In order to verify of building computer energy simulation methods, the Western Kentucky University (WKU) Office of Sustainability located at 503 Regents Ave. in Bowling Green KY …

Redox-Responsive Polysulfide-Based Biodegradable Organosilica Nanoparticles For Delivery Of Bioactive Agents, Seyyed Pouya Hadipour Moghaddam, Jiban Saikia, Mostafa Yazdimamaghani, Hamidreza Ghandehari

Chemical and Biochemical Engineering Faculty Research & Creative Works

Design and development of silica nanoparticles (SiO2 NPs) with a controlled degradation profile promises effective drug delivery with a predetermined carrier elimination profile. In this research, we fabricated a series of redox-responsive polysulfide-based biodegradable SiO2 NPs with low polydispersity and with variations in size (average diameters of 58 ± 7, 108 ± 11, 110 ± 9, 124 ± 9, and 332 ± 6 nm), porosity, and composition (disulfide vs tetra sulfide bonds). The degradation kinetics of the nanoparticles was analyzed in the presence of 8 mM glutathione (GSH), mimicking the intracellular reducing condition. Results indicate that porosity and core composition …

Characterization Of Surface Charges And Compensating Charges For Gene Delivery To Tissue, Ravi Shanmugha Preethi Vangapattu

USF Tampa Graduate Theses and Dissertations

Ever since the discovery of DNA, there has been many pathologies identified effecting mankind. With the development in technology, there are many methods to alleviate these pathologies. One such is gene therapy or gene delivery. It is a process of introducing some foreign material into the body to correct the effected cells. In principle, it is a modern method to cure cells or a method to transfer nucleic acid into a cell to treat specific cells in the body. The process of delivering a genetic material is carried out using vectors, namely, viral vectors and non-viral vectors. In viral vectors, …

Comparative Analysis Of Tag Estimation Algorithms On Rfid Epc Gen-2 Performance, Arundhoti Ferdous

USF Tampa Graduate Theses and Dissertations

In a passive radio-frequency identification (RFID) system the reader communicates with the tags using the EPC Global UHF Class 1 Generation 2 (EPC Gen-2) protocol with dynamic framed slotted ALOHA. Due to the unique challenges presented by a low-power, random link, the channel efficiency of even the most modern passive RFID system is less than 40%. Hence, a variety of methods have been proposed to estimate the number of tags in the environment and set the optimal frame size. Some of the algorithms in the literature even claim system efficiency beyond 90%. However, these algorithms require fundamental changes to the …

Impaired Right Ventricular Contractile Function In Childhood Obesity And Its Association With Right And Left Ventricular Changes: A Cine Dense Cardiac Magnetic Resonance Study, Linyuan Jing, Arichanah Pulenthiran, Christopher D. Nevius, Abba Mejia-Spiegeler, Jonathan D. Suever, Gregory J. Wehner, H. Lester Kirchner, Christopher M. Haggerty, Brandon K. Fornwalt

Biomedical Engineering Faculty Publications

Background: Pediatric obesity is a growing public health problem, which is associated with increased risk of cardiovascular disease and premature death. Left ventricular (LV) remodeling (increased myocardial mass and thickness) and contractile dysfunction (impaired longitudinal strain) have been documented in obese children, but little attention has been paid to the right ventricle (RV). We hypothesized that obese/overweight children would have evidence of RV remodeling and contractile dysfunction.

Methods: One hundred and three children, ages 8–18 years, were prospectively recruited and underwent cardiovascular magnetic resonance (CMR), including both standard cine imaging and displacement encoding with stimulated echoes (DENSE) imaging, which allowed …

A Wood-Powered Lawn Mower: Separating The Rules Of Thumb From Engineering Design, William White

Mahurin Honors College Capstone Experience/Thesis Projects

Biomass gasification, the thermal process of exracting combustible gasses from organic matter, is an established procedure that has been used for many years to provide fuel in various applications. It is a potential source of renewable fuel and has proven useful as a crisis energy source. This thesis investigates the primary engineering science principles involved in gasifier-engine system design. It arises from and supplements a WKU mechanical engineering senior project. The senior project has developed a wood gasification system designed to power a riding lawn mower. The thesis reiews theory-based design and separates it from informal hit and miss approaches—rule …

Characteristics And Mechanism For The Simons Electrochemical Fluorination Of Methanesulfonyl Fluoride, Wen-Lin Xu, Bao-Tong Li, Da-Wei Wang, Ya-Qiong Wang

Journal of Electrochemistry

The characteristics and mechanism for the Simons electrochemical fluorination processes were investigated during the electrochemical fluorination of CH₃SO₂F to CF₃SO₂F. The results showed that the reaction mechanism for the electrochemical fluorination of organic compounds to organic fluorides was the same as that of chemical fluorination processes using fluorinating agents such as CoF₃. The electrochemical fluorination in anhydrous HF was a heterogeneous process, and nickel fluorides on the surface of the nickel anode played the role of a mediator in the Simons process to transfer oxidation potential from the anode to …

Ionic Liquid-Supported Tempo/Polymeric Ionic-Liquid/Carbon Black Ternary Composites: Preparations And Applications In Electrochemical Oxidation Of Alcohols, Xin Lin, Cao-Cao Sun, Zhi-Rong Liu, Cheng-Chu Zeng

Journal of Electrochemistry

To effectively recover redox catalyst and supporting electrolyte, a novel ternary composite consisting of ionic liquid-supported TEMPO, polymeric ionic-liquid and carbon black was prepared. The ionic-liquid supported redox catalyst TEMPO-IL-BF₄ was firstly synthesized from 4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl, and followed by the reaction of polydimethyldiallylammonium chloride (PDDA) and bis(trifluoromethane)sulfonimide lithium salt (LiTFSI) to form poly[diallyldimethylammonium bis(trifluoromethanesulfonyl)imide] (PDDA(Tf₂N)). A combination of the above mentioned two synthesized materials and carbon black afforded to obtain the ternary composite, which was used as the recoverable supporting electrolyte and mediator for the electrochemical oxidation of alcohol. The results indicate that various alcohols could be oxidized …

Electrochemical Deposition Of Cr From Cr3+ In The Mixed Electrolyte Of [Bmim]Oac/H2O, Wei Luo, Dong-Fang Niu, Rong-Bin Du, Jun-Wei Wang, Zhu-Qing Wang, Heng Xu, Xin-Sheng Zhang

Journal of Electrochemistry

The electrochemical reduction of trivalent chromium ion (Cr³⁺) to Cr in 1-butyl-3-methylimidazolium acetate ([BMIM]OAc)-H₂O mixed electrolyte was investigated. The cyclic voltammograms showed that the electroreduction of Cr³⁺ in the mixed electrolyte occurred in a two-step process, namely, Cr³⁺ + e → Cr²⁺ and Cr²⁺ + 2e→ Cr⁰, controlled by the diffusion of Cr³⁺ to the electrode. The diffusion coefficient of Cr³⁺ was 1.2×10^-8 cm²/s at 40 ℃ obtained by Rendle-Sevcik equation. The chronoamperomograms of the Cr³⁺ electrodeposition confirmed the three-dimensional instantaneous nucleation mechanism of …

Effects Of Short Term Hypoxia-Preconditioning On Glial Phenotype Induction Of Human Mesenchymal Stem Cells, Zichen Qian, Qi Xing, Corey Fase, Kyle Jansen, Feng Zhao

Michigan Tech Publications, Part 1

Development of successful clinical treatments for peripheral nerve injury is limited due to the complications behind neural physiology. Human mesenchymal stem cells (hMSCs) have the ability to directly promote tissue repair and protect cells at the injury site. Studies have shown that hMSCs can be transplanted to improve nerve regeneration. Hypoxic culture condition has been proven to maintain the stemness of hMSCs for later differentiation. In this study, we investigated the effects of low oxygen (O₂) (2% and 5% O₂) pre-treatment and initial seeding density (500, 1000, and 2000 cells/cm²) on glial protein expression …

Electrocarboxylation: An Effective Process For Fixation Of Co2 Into Organic Carboxylic Acids, Huan Wang, Jia-Xing Lu

Journal of Electrochemistry

Conversion and utilization of greenhouse gas carbon dioxide (CO₂) have become more and more significant to the sustainable development of the global economy. Among them, electrocarboxylation of organic substrates is an effective process. Under mild conditions such as ambient temperature and pressure, carbocations generated by electroreduction of organic substrates can react with CO₂ into corresponding carboxylic acids. This paper introduces the recent progress of our group in electrochemical carboxylation, including electrocarboxylation of varies active organic substrates and asymmetric electrocarboxylation.

Wastewater Treatment Process Based On Microbial Electrochemistry: Opportunities And Challenges, Wei-Hua He, Jia Liu, Hai-Man Wang, Yu-Jie Feng

Journal of Electrochemistry

Microbial electrochemical technology (MET) has drawn great attention for its characteristics of synergetic pollution removal and energy recovery of wastewater. In the last decade, significant developments in microbial electrochemical system (MES) have been made in the aspects of electron transfer mechanism, microbial community analysis, function expansion, low-cost electrode materials and scaled-up constructions. However, the feasibility of MET as a wastewater treatment process has been controversial so far. In this paper, the characteristics of MET were systematically compared with anaerobic and aerobic processes from the application point of view in the aspects of pollution degradation and energy recovery processes. The MET-based …

Electrochemical Synthesis Of Homoallylic Alcohols And Homoallylic Amines, Wei-Qiang Zhong, Xiang-Hui Liang, Jing-Mei Huang

Journal of Electrochemistry

Electrochemical technique has been widely applied in the organic synthesis. This review focuses on the electrochemical synthesis of homoallylic alcohols and homoallylic amines from the allylation of carbonyl compounds and imines. This method has been developed impressively, especially in the field of electrochemical allylation in a green solvent of aqueous media. Improvement of the efficiency of the electricity, regio-selectivity and chiral synthesis are expected.

Preparations And Applications Of Irsnox Electrode In Electrochemical Synthesis Of 2,5-Dichlorophenol, Xiang-Yu Ma, Xu-Guo Tu, Rui-Nan He, Ya Chen, Gui-Sheng Zhu, Shou-Yan Shao, Song Chen

Journal of Electrochemistry

The electrodes of titanium based iridium tin oxides (IrSnOx) have been prepared by traditional thermal decomposition method and further applied to the electrosynthsis of 2,5-dichlorophenol in order to explore a green and high efficient synthesis route. The results showed that the electrode surface existed apparent cracks, while the intermediate layer prepared with Sn:Sb=94:6 existed less cracks and longer life time. The main products of the electrolytic reaction were 2,5-dichlorophenol, p-chlorophenol, and 1,2,4-trichlorobenzene. The electrosynthsis yield of 2,5-dichlorophenol reached 57% and the selectivity of 2,5-dichlorophenol was as high as 93% by using the IrSnOx as an anode, which is obviously better …

Electrocatalysis Of Nanotin Dioxide In The Battery Reaction Of Zinc-Nitrobenzene, Xu-Guo Tu, Xiang-Yu Ma, Rui-Nan He, Xiao-Juan Wang, Chen Ling, Yun-Xia Sun, Song Chen

Journal of Electrochemistry

The tin dioxide (SnO₂) nanoparticles were synthesized by using a simple hydrothermal route in the presence of tetrapropyl ammonium bromide (TPAB) as a surfactant. Accordingly, the titanium mesh based SnO₂ catalyst electrode was prepared. The morphologies and structures of SnO₂ nanostructures were characterized by scanning electron microscopy and X-ray diffraction spectrometry. The influences of reactant concentration, reaction temperature and time on the morphology of the products were investigated in detail. The electrocatalytic performance of SnO₂ for the reduction of nitrobenzene with zinc was studied. Possible formation process and growth mechanism for such hierarchical SnO_{2 …}

Selective Direct Electro-Oxidation Of C-H Bond, Yan-Mei Liao, Qian-Qian Wu, An-Lun Zhang, Ying-Hong Zhu, Chun-An Ma

Journal of Electrochemistry

Carbon-hydrogen (C-H) bond is the most basic chemical bond in organic compounds. The activation and direct conversion of C-H bond are the effective methodology for synthesis of different kinds of organic compounds from alkane compounds. The oxidative activation and functionalization of C-H bonds constitute an important and challenging area of investigation. The electro-oxidative activation of C-H bonds to form new C-O, C-C and C-N bonds has proven to be interesting and important in organic chemistry using the clean electron as the oxidant. The target C-O, C-C and C-N compounds could be selectively achieved by choosing the appropriate electrode, supporting electrolyte …

Multiple Scattering Theory For Heterogeneous Elastic Continua With Strong Property Fluctuation: Theoretical Fundamentals And Applications, Huijing He

Department of Mechanical and Materials Engineering: Faculty Publications

Scattering of elastic waves in heterogeneous media has become one of the most important problems in the field of wave propagation due to its broad applications in seismology, natural resource exploration, ultrasonic nondestructive evaluation and biomedical ultrasound. Nevertheless, it is one of the most challenging problems because of the complicated medium inhomogeneity and the complexity of the elastodynamic equations. A widely accepted model for the propagation and scattering of elastic waves, which properly incorporates the multiple scattering phenomenon and the statistical information of the inhomogeneities is still missing. In this work, the author developed a multiple scattering model for heterogeneous …

Libraries Embrace The Engineering Grand Challenges, James A. Van Fleet

Faculty Conference Papers and Presentations

The National Academy of Engineering has put forward 14 Grand Challenges for Engineering in the 21st Century. These are addressed by students at participating universities through a Grand Challenge Scholars Program. Each program is unique, approved by application to the NAE, and administered by faculty and staff at the participating institution.

There are obvious opportunities for libraries and librarians to be an active part of the GCSP. Students are required to develop a research project around one of the challenges. They may take courses designed with the Grand Challenges in mind, seek out opportunities to develop global perspectives, and participate …

Preparations And Characterizations Of Ti/Pbo2 Electrodes Modified With Rare Earth Of Praseodymium And Pvp In Electrochemical Degradation Of Organics, Mai Xu, Feng-Wu Wang, Xian Liang, Yi-Jun Wei, Wen-Yan Fang, Chuan-Gao Zhu, Yun-Hu Hun

Journal of Electrochemistry

The titanium (Ti) based lead oxide (PbO₂) electrodes doped with praseodymium oxide (Pr₂O₃) and polyvinylpyrrolidone (PVP) were prepared by electrodeposition. The surface morphologies and structures of the as-prepared thin films were characterized by scanning electron microscopy (SEM) and X-ray diffraction (XRD) technique, respectively. The results showed that the denser and more uniform coatings with smaller particles and larger surfaces were obtained by doping, which modified the micro-structure of the Ti/SnO₂-Sb₂O₃/Pr₂O₃-PVP-PbO₂ electrode. Cyclic voltammetry (CV) was also used to study the electrocatalytic activity of …

1950 - Digitization Of 1949 Dwr Bulletin 52 – Groundwater Wells In Salinas Valley And Vicinity [Draft]

Groundwater Basin Maps

A 2017 digital representation of groundwater wells in the Salinas Valley and surrounding area as depicted on 1949 maps found in the California Department of Public Works, Division of Water Resources, Bulletin No. 52-A, Salinas Basin Investigation, Basic Data, 1949.