Engineering Commons^™

Development Of A Tabletop Coherent Soft X-Ray Source, Hanfu Kong

Electronic Theses and Dissertations

The goal of this thesis is to design a tabletop coherent soft X-ray source for attosecond high resolution imaging. We collect signals from gas cells with different length and lens with different focal length. A spectrometer with a grating and a CCD camera is applied to observe and measure the spectrum of the X-ray attosecond pulses. This thesis first introduces the theory background of ultrafast lasers, then mainly explains high harmonic generation, which is the key method for attosecond pulses generation, subsequently presents the experiment system and analyzes the results from the experiment, also compares different combinations of parameters of …

Fast Compressed Automatic Target Recognition For A Compressive Infrared Imager, Brian Millikan

Electronic Theses and Dissertations

Many military systems utilize infrared sensors which allow an operator to see targets at night. Several of these are either mid-wave or long-wave high resolution infrared sensors, which are expensive to manufacture. But compressive sensing, which has primarily been demonstrated in medical applications, can be used to minimize the number of measurements needed to represent a high-resolution image. Using these techniques, a relatively low cost mid-wave infrared sensor can be realized which has a high effective resolution. In traditional military infrared sensing applications, like targeting systems, automatic targeting recognition algorithms are employed to locate and identify targets of interest to …

An Engineering Analytics Based Framework For Computational Advertising Systems, Mengmeng Chen

Electronic Theses and Dissertations

Engineering analytics is a multifaceted landscape with a diversity of analytics tools which comes from emerging fields such as big data, machine learning, and traditional operations research. Industrial engineering is capable to optimize complex process and systems using engineering analytics elements and the traditional components such as total quality management. This dissertation has proven that industrial engineering using engineering analytics can optimize the emerging area of Computational Advertising. The key was to know the different fields very well and do the right selection. However, people first need to understand and be experts in the flow of the complex application of …

Influence Of Chitosan-Alginate Scaffold Stiffness On Bone Marrow Stromal Cell Differentiation, Isabel Arias Ponce

Electronic Theses and Dissertations

Tissue grafts are the gold standard for replacing large volume tissue defects. Yet, they present several risks, including infection, low functional outcomes, and reduced graft integrity. Tissue engineering (TE) combines cells and biomaterial scaffolds to foster tissue growth and remodeling. Bone marrow stromal cells (BMSCs) have been shown to respond to the stiffness of their microenvironment, resulting in differentiation into different lineages. 3D porous chitosan-alginate (CA) scaffolds have been previously demonstrated for bone TE with osteoblasts and BMSCs; however, only a single scaffold composition (4 wt%) was studied. Three CA scaffold compositions (2, 4, 6 wt% CA) were produced. Scanning …

Cell Printing: An Effective Advancement For The Creation Of Um Size Patterns For Integration Into Microfluidic Biomems Devices, Megan Aubin

Electronic Theses and Dissertations

The Body-on-a-Chip (BoaC) is a microfluidic BioMEMs project that aims to replicate major organs of the human body on a chip, providing an in vitro drug testing platform without the need to resort to animal model testing. Using a human model also provides significantly more accurate drug response data, and may even open the door to personalized drug treatments. Microelectrode arrays integrated with human neuronal or human cardiac cells that are positioned on the electrodes are essential components for BoaC systems. Fabricating these substrates relies heavily on chemically patterned surfaces to control the orientation and growth of the cells. Currently, …

Liquid Crystal Phase Modulation For Beam Steering And Near-Eye Displays, Yun-Han Lee

Electronic Theses and Dissertations

Liquid crystal spatial phase modulator plays an important role in laser beam steering, wave-front shaping and correction, optical communication, optical computation and holography. One fundamental limitation lays in the response time of liquid crystal reorientation. To achieve fast response time, polymer-network liquid crystals are therefore proposed. By incorporating polymer network in a liquid crystal host, the response time can be reduced by a factor of 100. However, the polymer network introduces hysteresis, light scattering, and high voltage. The motivation for a fast-response liquid crystal phase modulator will be discussed in the first chapter. In the second chapter, we introduce our …

Some Aggregation Operators For Bipolar-Valued Hesitant Fuzzy Information, Florentin Smarandache, Tahir Mahmood, Kifayat Ullah, Qaisar Khan

Branch Mathematics and Statistics Faculty and Staff Publications

In this article we define some aggregation operators for bipolar-valued hesitant fuzzy sets. These operations include bipolar-valued hesitant fuzzy ordered weighted averaging (BPVHFOWA) operator, bipolar-valued hesitant fuzzy ordered weighted geometric (BPVHFOWG) operator and their generalized forms. We also define hybrid aggregation operators and their generalized forms and solved a decision-making problem on these operation.

Thermoresponsive, Redox-Polymerized Cellulosic Hydrogels Undergo In Situ Gelation And Restore Intervertebral Disc Biomechanics Post Discectomy, Devika Varma, H. A. Lin, R. G. Long, G. T. Gold, A. C. Hecht, J. C. Iadridis, Steven B. Nicoll

Publications and Research

Back and neck pain are commonly associated with intervertebral disc (IVD) degeneration. Structural augmentation of diseased nucleus pulposus (NP) tissue with biomaterials could restore degeneration-related IVD height loss and degraded biomechanical behaviors; however, effective NP replacement biomaterials are not commercially available. This study developed a novel, crosslinked, dual-polymer network (DPN) hydrogel comprised of methacrylated carboxymethylcellulose (CMC) and methylcellulose (MC), and used in vitro, in situ and in vivo testing to assess its efficacy as an injectable, in situ gelling, biocompatible material that matches native NP properties and restores IVD biomechanical behaviors. Thermogelling MC was required to enable consistent and timely …

Single-Site Catalyst Promoters Accelerate Metal- Catalyzed Nitroarene Hydrogenation, Liang Wang, Erjia Guan, Jian Zhang, Junhao Yang, Yihan Zhu, Yu Han, Ming Yang, Cheng Cen, Gang Fu, Bruce C. Gates, Feng-Shou Xiao

Faculty & Staff Scholarship

Atomically dispersed supported metal catalysts are drawing wide attention because of the opportunities they offer for new catalytic properties combined with efficient use of the metals. We extend this class of materials to catalysts that incorporate atomically dispersed metal atoms as promoters. The catalysts are used for the challenging nitroarene hydro- genation and found to have both high activity and selectivity. The promoters are single-site Sn on TiO2 supports that incorporate metal nanoparticle catalysts. Represented as M/Sn- TiO2 (M = Au, Ru, Pt, Ni), these catalysts decidedly outperform the unpromoted supported metals, even for hydrogenation of nitroarenes substituted with various …

Nanopulse Stimulation (Nps) Induces Tumor Ablation And Immunity In Orthotopic 4t1 Mouse Breast Cancer: A Review, Stephen J. Beebe, Brittany P. Lassiter, Siqi Guo

Bioelectrics Publications

Nanopulse Stimulation (NPS) eliminates mouse and rat tumor types in several different animal models. NPS induces protective, vaccine-like effects after ablation of orthotopic rat N1-S1 hepatocellular carcinoma. Here we review some general concepts of NPS in the context of studies with mouse metastatic 4T1 mammary cancer showing that the postablation, vaccine-like effect is initiated by dynamic, multilayered immune mechanisms. NPS eliminates primary 4T1 tumors by inducing immunogenic, caspase-independent programmed cell death (PCD). With lower electric fields, like those peripheral to the primary treatment zone, NPS can activate dendritic cells (DCs). The activation of DCs by dead/dying cells leads to increases …

Aviation Outreach Model And Gap Analysis: Examining Solutions To Address Workforce Shortages, Rebecca K. Lutte

Aviation Institute Faculty Publications

The purpose of this research is to examine aviation outreach programs to identify best practices and areas for improvement in the endeavor to recruit youth to the aviation industry. The research includes creation of a model of aviation outreach and development and application of an aviation outreach gap analysis design. Three programs are analyzed, Women in Aviation Girls in Aviation Day, Experimental Aviation Association Young Eagles, and Aircraft Owners and Pilots Association High School Aviation Initiative. Each program takes a unique approach to recruiting youth and the strengths and weaknesses, based on the aviation outreach model, are discussed. Results of …

University Of Nebraska At Omaha 2018-2019 Course Catalog, University Of Nebraska At Omaha

Undergraduate Catalogs

Located in one of America’s best cities to live, work and learn, the University of Nebraska at Omaha (UNO) is Nebraska’s premier metropolitan university. With more than 15,000 students enrolled in 200-plus programs of study, UNO is recognized nationally for its online education, graduate education, military friendliness, and community engagement efforts.Founded in 1908, UNO has served learners of all backgrounds for more than 100 years and is dedicated to another century of excellence both in the classroom and in the community.

The Design, Test And Evaluation Of A Sensing System For Process Analytical Technology (Pat), Trevor Murphy

Theses

Increased globalisation and competitiveness has given rise to a more dynamic and diverse global market that has begun to place incredible strain on manufacturing supply chains. Conventional manufacturing methods such as the batch manufacturing methods employed largely by the materials processing industries i.e. pharmaceuticals, polymers and magnesium processing plants are ill-suited to cope with the demands of today. As products evolve with technological advancements they become more complex to produce and require alternative approaches to manufacturing to ensure product quality while reducing costs and increasing manufacturing efficiencies.

A potential solution to the growing demands on today's supply chain is process …

Hosting Capacity Optimization In Modern Distribution Grids, Mansoor T. Alturki

Electronic Theses and Dissertations

The availability of distributed renewable energy resources and the anticipated increase in new types of loads are changing the way electricity is being produced and supplied to consumers. This shift is moving away from a network delivering power solely from centralized power plants towards a decentralized network which supplements its power production by incorporating local distributed generators (DGs). However, the increased integration of DGs into existing distribution networks is impacting their behavior in terms of voltage profile, reliability, and power quality. To determine the maximum amount of DG that distribution grids can accommodate the concept of hosting capacity is introduced. …

Automated Cfd Optimization To Maximize Wind Farms Performance And Land Use, Rafael Valotta Rodrigues

Electronic Theses and Dissertations

In this research, a computational system was designed to analyze and optimize the layout of wind farms under variable operational conditions. At first, a wind turbine computational fluid dynamic (CFD) model was developed covering the near wake. The near wake flow field was validated against near wake velocity data from the MEXICO experiment. The CFD simulation demonstrated that the tip speed ratio and the pitch angle greatly influence the near wake behavior, affecting the velocity deficit and the turbulence intensity profile in this region. The CFD model was extended to cover the far wake, aiming to become a computational tool …

Adrenergic Stimulation In Acute Hyperglycemia: Effects On Cellular And Tissue Level Murine Cardiac Electrophysiology, Sridevi Thyagarajan

Theses and Dissertations--Biomedical Engineering

Cardiovascular complications associated with elevated levels of glucose in the blood (Hyperglycemia, HG) is a growing health concern. HG is known to be associated with a variety of cardiovascular morbidities including higher incidence of electrical disturbances. Although effects of chronic HG have been widely investigated, electrophysiological effects of acute hyperglycemia are relatively less known. Further, hyperglycemic effects on adrenergic response is not widely investigated. We used excised ventricular tissues from mice to record trans-membrane potentials during a variety of pacing protocols to investigate cellular/tissue level electrophysiological effects of acute hyperglycemia and adrenergic stimulation (1µM Isoproterenol, a β-adrenergic agonist). A custom …

Effects Of Lumbar Spinal Fusion On Lumbopelvic Rhythm During Activities Of Daily Living, Cameron G. Slade

Theses and Dissertations--Biomedical Engineering

Abnormalities in lumbopelvic rhythm (LPR) play a role in occurrence/recurrence of low back pain (LBP). The LPR before spinal fusion surgery and its changes following the surgery are not understood. A repeated measure study was designed to investigate timing and magnitude aspects of LPR in a group of patients (n = 5) with LBP before and after a spinal fusion surgery. Participants completed a forward bending and backward return task at their preferred pace in the sagittal plane. The ranges of thoracic and pelvic rotations and lumbar flexion (as the magnitude aspects of LPR) as well as the mean absolute …

Multimodal Noncontact Diffuse Optical Reflectance Imaging Of Blood Flow And Fluorescence Contrasts, Daniel Irwin

Theses and Dissertations--Biomedical Engineering

In this study we design a succession of three increasingly adept diffuse optical devices towards the simultaneous 3D imaging of blood flow and fluorescence contrasts in relatively deep tissues. These metrics together can provide future insights into the relationship between blood flow distributions and fluorescent or fluorescently tagged agents. A noncontact diffuse correlation tomography (ncDCT) device was firstly developed to recover flow by mechanically scanning a lens-based apparatus across the sample. The novel flow reconstruction technique and measuring boundary curvature were advanced in tandem. The establishment of CCD camera detection with a high sampling density and flow recovery by speckle …

Sleep And Thermoregulation: A Study Of The Effect Of Ambient Temperature Manipulation On Mouse Sleep Architecture, Asma'a A. Ajwad

Theses and Dissertations--Biomedical Engineering

Good quality sleep is essential for mental and physical health. Inadequate sleep impacts memory consolidation, learning and cognition, immune function, autonomic regulation, physical performance, and other vital functions. In many neurological disorders that are associated with sleep problems such as epilepsy and Alzheimer’s disease, changes in brain circuitry affect sleep-wake regulation mechanisms; this is reflected in anomalous sleep-wake architecture and usually accompanied by poor sleep depth. Thus, over many years, many approaches have been tried in humans and animal models with the goal of improving sleep quality. Unfortunately, each of those approaches comes with limitations or side effects. Thus, there …

Lower Back Biomechanics At Non-Chronic Stage Of Low Back Pain, Iman Shojaei

Theses and Dissertations--Biomedical Engineering

Prior studies have reported differences in lower back biomechanics during activities of daily living between individuals with and without chronic low back pain (LBP). Nevertheless, the literature on lower back biomechanics of patients with non-chronic LBP is scant. Therefore, the objective of this study, as the first step towards future prospective studies, was to investigate the lower back biomechanics in patients with non-chronic LBP. Case-control studies were conducted wherein measures of lumbo-pelvic coordination during bending and return tasks as well as measures of mechanical demand on the lower back during lifting tasks in the sagittal plane were investigated between patients …

Segmentation Strategies For Road Safety Analysis, Eric R. Green

Theses and Dissertations--Civil Engineering

This dissertation addresses the relationship between roadway segment length and roadway attributes and their relationship to the efficacy of Safety Performance Function (SPF) models. This research focuses on three aspects of segmentation: segment length, roadway attributes, and combinations of the two. First, it is shown that choice of average roadway segment length can result in markedly different priority lists. This leads to an investigation of the effect of segment length on the development of SPFs and identifies average lengths that produce the best-fitting SPF. Secondly, roadway attributes are filtered to test the effect that homogeneity has on SPF development. Lastly, …

Assessment Of Watershed Nutrient Loads And Effectiveness Of Best Management Practices, Saeid Nazari

Theses and Dissertations--Civil Engineering

Several methods have been developed for use in estimating the water quality loads associated with urban and agricultural landuses and practices. These include the use of sophisticated computer models, typically based on using pollutant loading and runoff functions, regression equations, load export coefficients (LECs), and event mean concentrations (EMCs). This research has examined the feasibility of using a simple EMC approach with the Kentucky Nutrient Model (KYNM). The thesis includes an extensive literature review of EMCs and a synthesis of recommended values for a range of typical urban and agricultural landuses. The thesis also includes an extensive literature review of …

Preferential Pathways For Vapor Intrusion: Site Screening And Field Sampling Of Sewers To Assess Inhalation Exposure Risks, Evan James Willett

Theses and Dissertations--Civil Engineering

Hazardous waste sites and aging wastewater infrastructure are common in the United States. There are hundreds of thousands of contaminated sites and more than a million miles of sewer pipes. Populations living close to hazardous waste sites often suffer from increased risk of adverse health effects due to exposure to contaminated environmental media. Vapor intrusion is one process by which nearby populations can be exposed to volatile organic compounds (VOCs). Aging wastewater infrastructure is important for vapor intrusion site assessments because sewer pipes can serve as preferential vapor transport pathways. Near contaminated sites, pipe deterioration allows migration of contaminants into …

Advanced Technologies For Efficient Transportation Construction Inspection, Clyde Wesley Newcomer Iv

Theses and Dissertations--Civil Engineering

Collecting load tickets is an example of an antiquated practice that puts inspectors in harm’s way either adjacent to traffic, in close proximity to moving or backing equipment, or at times requires climbing onto trucks to reach tickets. Technology exists to collect this information electronically allowing for safer, efficient inspection methods. Departments of Transportation are charged with inspecting an increasing work load with a diminishing number of inspection staff. Recently, doing more with less has led to the prioritization of inspection activities and resulted in less collection of data and visual inspection on projects. Technology advancements are available to improve …

Quantifying Non-Recurrent Delay Using Probe-Vehicle Data, Jacob Douglas Keaton Brashear

Theses and Dissertations--Civil Engineering

Current practices based on estimated volume and basic queuing theory to calculate delay resulting from non-recurrent congestion do not account for the day-to-day fluctuations in traffic. In an attempt to address this issue, probe GPS data are used to develop impact zone boundaries and calculate Vehicle Hours of Delay (VHD) for incidents stored in the Traffic Response and Incident Management Assisting the River City (TRIMARC) incident log in Louisville, KY. Multiple linear regression along with stepwise selection is used to generate models for the maximum queue length, the average queue length, and VHD to explore the factors that explain the …

Performance Of The Grout Curtain At The Kentucky River Lock And Dam No. 8, Robert C. Hatton

Theses and Dissertations--Civil Engineering

Karst bedrock conditions and deterioration of the lock and dam structures have resulted in significant leakage through, underneath, and around Lock and Dam No. 8 on the Kentucky River. During severe droughts, the water surface in Pool No. 8 has been observed to drop below the crest of the dam, resulting in water supply shortages and water quality issues for surrounding communities reliant on the pool. Presently, the primary purpose of Lock and Dam No. 8 is water supply. Pool No. 8 is currently where the cities of Nicholasville (Jessamine County, KY) and Lancaster (Garrard County, KY) draw their water. …

Performance Of Two Tieback Walls And Rock Anchors In A Shale Stratum, Jorge Octavio Romana Giraldo

Theses and Dissertations--Civil Engineering

Tieback walls are typically design based on predetermined pressure distribution; however, these pressures were proposed based on performance of excavations. For retaining walls used in slope remediation, the application of these pressures might not be adequate; the construction procedure; therefore, a different response of the wall is expected. This document, presents the performance of two tieback walls installed in a shale stratum. Monitored responses is correlated with construction activities; these activates implied excavation and backfilling in both of the tieback walls. In addition, this research shows a numerical procedure to evaluate the anchor capacity based on the t- z approach. …

Numerical Modeling And Isotope Tracers To Investigate Karst Biogeochemistry And Transport Processes, Admin Husic

Theses and Dissertations--Civil Engineering

This dissertation investigated the physical and biogeochemical processes affecting the source, fate, and transport of sediment, carbon, and nitrogen within a highly-coupled fluviokarst system. Elemental and isotopic datasets were collected at surface and subsurface locations for both dissolved and particulate contaminant phases, new methodology regarding data collection was presented to the karst research community, an in-cave sediment transport model coupling physical transport with elemental and isotopic mass balances of carbon and nitrogen was formulated, pathway and process control on nitrate leaching from agricultural karst watersheds was assessed, and nitrate mobilization and fractionation were modeled using high frequency storm sampling and …

Direct Measurement Of Crosstie-Ballast Interface Pressures Using Granular Material Pressure Cells, Travis James Watts

Theses and Dissertations--Civil Engineering

The magnitudes and relative pressure distributions transmitted to the crosstie-ballast interface of railroad track significantly influences the subsequent behavior and performance of the overall track structure. If the track structure is not properly designed to distribute the heavy-axle loads of freight cars and locomotives, deficiencies and inherent failures of the crossties, ballast, or underlying support layers can occur, requiring substantial and frequent maintenance activities to achieve requisite track geometrical standards. Incorporating an understanding of the pressure distribution at the crosstie-ballast interface, appropriate designs can be applied to adequately provide a high performing and long-lasting railroad track. Although this can be …

Understanding Inhibition Of A Biodesulfurization Enzyme To Improve Sulfur Removal From Petroleum, Yue Yu

Theses and Dissertations--Chemical and Materials Engineering

The biodesulfurization 4S-pathway is a promising complementary enzymatic approach to remove sulfur from recalcitrant thiophenic derivatives in petroleum products that remain from conventional hydrodesulfurization method without diminishing the calorific value of oil. The final step of this pathway involves the carbon-sulfur bond cleavage from HBPS, and the production of the final products 2-hydroxybiphenyl (HBP) and sulfite, has been recognized as the rate-limiting step, partially as a result of product inhibition. However, the mechanisms and factors responsible for product inhibition in the last step have not been fully understood. In this work, we proposed a computational investigation using molecular dynamic simulations …