Engineering Commons^™

Machine Learning And Deep Learning Applications In Neuroimaging, Gowtham Krishnan Murugesan

Bioengineering Dissertations - Archive

Deep Learning (DL) tools have the potential to analyze large datasets and extract meaningful insights to enhance patient outcomes. Radiological images such as MRI and CT, often contain complex patterns that can be difficult and time consuming to evaluate manually. Deep learning algorithms can improve treatment decisions and patient care beyond the realm of research. The goal of this dissertation is to apply advanced deep learning methods in three distinct domains of neuroimaging, 1.fMRI Analysis, 2. MR Image Synthesis, and 3. Clinical applications in brain tumors. First, we developed a new fMRI network inference method named as BrainNET using Machine …

In Vivo Ultrasound-Switchable Fluorescence Imaging And Its Applications, Tingfeng Yao

Bioengineering Dissertations - Archive

The conventional fluorescence imaging has limited spatial resolution in centimeters-deep tissue because of the tissue’s high scattering property. Ultrasound-switchable fluorescence (USF) imaging, a new imaging technique, was recently proposed to realize high-resolution fluorescence imaging in centimeters-deep tissue. Although promising results were achieved in tissue-mimic phantoms or tissue samples, the in vivo USF imaging had not been realized so far. There were two major challenges in realizing in vivo USF imaging. First, the lack of stable near-infrared (NIR) USF contrast agents in a biological environment and the lack of data about their biodistributions. Second, the previous USF imaging systems adopted a …

The Biomechanics Of Cardiac Elastin And Its Role In Bioengineering, Sara R. Mcmahan

Bioengineering Dissertations - Archive

Elastin is an essential structural protein responsible for the elasticity of many tissues, including skin, lungs, blood vessels, and other highly dynamic tissues and organs in the body. In the heart, cardiac elastin has been largely ignored as one of the key players in heart health and functionality. In this study, we will fill the knowledge gap with novel experiments and biomechanical investigations that will allow us to understand the roles of elastin in cardiac biomechanics, as well as explore the bioengineering applications of elastin-rich cardiac tissues. For Aim 1, we performed a biomechanical and ultrastructural comparison of the elastin-rich …

Impact Of Muscular Fatigue And Its Modulation Using Transcranial Photobiomodulation (Tpbm) On The Human Brain Measured By Functional Near-Infrared Spectroscopy (Fnirs), Elizabeth Lyde Urquhart

Bioengineering Dissertations - Archive

When performing exercise, the brain must register and simultaneously integrate input from feedforward (i.e., central command) and feedback (e.g., exercise pressor reflex) neural mechanisms to make appropriate cardiovascular adjustments to meet metabolic demands. Muscle fatigue occurs during prolonged exercise and is characterized by a reduction in force-generating capability of the muscle. Fatigue comprises of two components: central and peripheral fatigue. Peripheral fatigue is produced at or distal to the neuromuscular junction whereas, central fatigue originates in the central nervous system. However, central fatigue’s contribution to peripheral fatigue is less understood and functional neuroimaging is being investigated as a tool to …

Quantifying Shallow Depth Concrete Delaminations Using Impact Echo, Mantaka Mahjabin Momo

Civil Engineering Theses - Archive

Delamination is a type of deterioration commonly found in concrete structures. It may form due to corrosion of embedded steel, poor construction, excessive vibration, or lack of bonding in composite construction. Impact echo (IE) is a simple and straightforward non-destructive testing (NDT) technique that is used to detect the presence and extent of delamination within concrete structures. It is capable of detecting its presence of delaminations in deep depths, but cannot accurately measure the defects that are near the surface. This phenomenon occurs due to the differences in the vibration modes of deep and shallow depth delaminations. The objective of …

Durability And Prediction Of Long-Term Performance Of Carbon Fiber Reinforced Polymer (Cfrp) Laminates Under Environmental Conditions, Eyad Alsuhaibani

Civil Engineering Dissertations - Archive

Strengthening deteriorated concrete structures with carbon fiber reinforced polymer (CFRP) has been widely validated through laboratory experiments and field tests. Questions and concerns persist related to the CFRP’s long-term performance and service life, however, thus the main objective of this research was to evaluate its durability under various environmental conditions. This research is divided into four distinct phases. In the first phase, the deterioration trends of CFRP laminate under environmental regimes were evaluated after immersion in water at 23, 45, and 60 °C for periods up to 32 weeks. In the second phase, four prediction models of the long-term performance …

Targeting The Oligomannose Biomarker Present On Distinct Subsets Of Non-Hodgkin Lymphomas, Butaek Lim

Bioengineering Dissertations - Archive

Subtypes of B cell non-Hodgkin’s lymphomas, including follicular lymphomas, have shown a unique high oligomannose presentation on their immunoglobulins that will interact with natural receptors of the innate immunity, reportedly causing stimulation and proliferation. From next generation deep sequencing of the variable heavy and light chain sequences of follicular lymphoma involved tissue sections, we identified the consensus variable sequences possessing glycosylation sites at the complementarity determining region. Using this information, we developed a cell line, referred to here as BZ, which displays the consensus variable segments as part of a surface antibody (IgM) and confirmed its presentation of high oligomannose …

Modulation Of Physiologic Responses Of Insulin Secreting Cells Using Electrical And Photostimulation, Caleb Nathaniel Liebman

Bioengineering Dissertations - Archive

Islet transplantation is a surgical procedure aimed at providing insulin independence to those suffering with Type I diabetes. Prior to implantation, a therapeutic window exists ex vivo where the cells can be treated in order to improve the procedure’s efficacy. It is well established that physical stimuli are able to affect cellular functionality. Thus the work herein is designed to elucidate the effects and mechanisms by which the insulin secreting β-cells respond to non-invasive electric field stimulation and photobiomodulation. Insulin secreting β-cells are an electrically active cell type and utilize their calcium dynamics to control insulin secretion. The calcium dynamics …

Nanoparticle-Based Approaches In Cardiovascular Diseases, Aneetta E. Kuriakose

Bioengineering Dissertations - Archive

Percutaneous coronary intervention (PCI) such as balloon angioplasty and stent placement are commonly employed for myocardial revascularization. These strategies, however, injure the arterial wall initiating a cascade of inflammatory responses that culminates in restenosis. Attempts are currently being made to improve the stents/balloon designs such that they suppress the inflammatory responses and support/enhance in situ reendothelialization. But the healing of the injured artery remains a major challenge. Therefore, in this work, we propose to characterize and identify a suitable fluorescent nanoparticle system that has potential to be used as vascular drug carriers. We also developed nanoparticles (NPs) that could enhance …

Novel Quantification Of Neurovascular Coupling (Nvc) To Predict Brain Injury In Neonates With Hypoxic Ischemic Encephalopathy, Yudhajit Das

Bioengineering Dissertations - Archive

Birth asphyxia is a global burden in clinical neonatal care. It results from deprivation of oxygen to a newborn infant that lasts too long during the birth causing physical harm to the brain. The asphyxia insult impairs fetal cerebral blood flow and results in a distinctive neonatal encephalopathy (NE). Hypoxic-ischemic encephalopathy (HIE) accounts for a significant proportion of encephalopathic newborns. Currently there is no reliable quantitative metric is available to predict outcome of neurological injury in neonates with HIE at the bedside in the first day of life. My dissertation targets on this gap by developing novel quantification methods of …

Whole-Head Functional Brain Imaging Of Economic Risk Decision Making And Transcranial Photobiomodulation With Fnirs And Eeg, Hashini I. Wanniarachchi Kankanamalage

Bioengineering Dissertations - Archive

Functional near-infrared spectroscopy (fNIRS) and electroencephalography (EEG) are two non-invasive brain imaging or mapping modalities that allow us to measure cerebral hemodynamic and electrophysiological changes in the human brain, respectively. LABNIRS is a cutting-edge, whole-head, optical brain mapping system with 40 pairs of light sources (at 780 nm830 nm) and 40 detectors, forming up to 133 detection channels. In my study, whole-head LABNIRS and 64-channel EEG were utilized to investigate respective alterations in response to risk decision- making under business context and to non-invasive photobiomodulation. As the first part of my study, I utilized fNIRS (i.e., LABNIRS) as a tool …

Sorption-Mediated Chemical Processes For The Versatile Treatment Of Per- And Polyfluoroalkyl Substances (Pfas) In Complex Media, Naomi Gevaerd De Souza

Civil Engineering Dissertations - Archive

In recent years, per- and polyfluoroalkyl substances (PFAS) have gained notoriety due to environmental and health concerns. These molecules are chemically stable which contributes to their persistence in biological systems and their increased detections in surface waters. Treatment of highly persistent PFAS has been a challenging but significant task. The most practical technique for removal of PFAS is through adsorption onto granular activated carbon (GAC) or other novel materials. Meanwhile, PFAS are resistant to simple oxidation, and although decomposition of specific PFAS has been reported through advanced oxidation technologies, often energy-intense technologies capable of generating electrons such as ultraviolet radiation, …

Evaluation Of Long Term Durability In Concrete With External Pre-Saturated Cfrp Laminate, Ramya Anandhan

Civil Engineering Theses - Archive

Many studies have investigated the use of carbon fiber reinforced polymer (CFRP) wraps to strengthen structural members, but there is limited literature on the application of presaturated CFRP wraps on reinforced concrete members. The main objective of this research is to study the long-term effectiveness of presaturated CFRP wraps in preventing corrosion of reinforced concrete specimens in severe environments. This paper presents numerical and experimental studies that were conducted to determine whether CFRP presaturated wraps provide a barrier against the ingress of chloride and permeability of water into concrete and thereby decelerate the corrosion process. The results show that the …

An Experimental Study Of Coupled Thermo-Hydro Behavior In Unsaturated Soil, Nice Kaneza

Civil Engineering Theses - Archive

Understanding unsaturated soils in response to the impact of temperature will better predict the performance of geo-structures that extract and inject underground heat. Previous studies have shown that heat and water in unsaturated soil affect the movement of each other and that thermal gradients are responsible for the migration of water and thermal properties. Therefore, it is essential to study the coupling behavior of thermal and hydraulic (TH) processes to analyze the distribution of moisture and thermal properties of unsaturated soil. These processes are transient and difficult to examine in the field. In addition, there is a lack of laboratory …

Data Quality And Reliability Assessment Of Wearable Emg And Imu Sensor For Construction Activity Recognition, Srikanth Sagar Bangaru, Chao Wang, Fereydoun Aghazadeh

Faculty Publications

The workforce shortage is one of the significant problems in the construction industry. To overcome the challenges due to workforce shortage, various researchers have proposed wearable sensor-based systems in the area of construction safety and health. Although sensors provide rich and detailed information, not all sensors can be used for construction applications. This study evaluates the data quality and reliability of forearm electromyography (EMG) and inertial measurement unit (IMU) of armband sensors for construction activity classification. To achieve the proposed objective, the forearm EMG and IMU data collected from eight participants while performing construction activities such as screwing, wrenching, lifting, …

Design Of An Offline Handwriting Recognition System Tested On The Bangla And Korean Scripts, Nishatul Majid

Boise State University Theses and Dissertations

This dissertation presents a flexible and robust offline handwriting recognition system which is tested on the Bangla and Korean scripts. Offline handwriting recognition is one of the most challenging and yet to be solved problems in machine learning. While a few popular scripts (like Latin) have received a lot of attention, many other widely used scripts (like Bangla) have seen very little progress. Features such as connectedness and vowels structured as diacritics make it a challenging script to recognize. A simple and robust design for offline recognition is presented which not only works reliably, but also can be used for …

Analyzing The Fractal Dimension Of Various Musical Pieces, Nathan Clark

Industrial Engineering Undergraduate Honors Theses

One of the most common tools for evaluating data is regression. This technique, widely used by industrial engineers, explores linear relationships between predictors and the response. Each observation of the response is a fixed linear combination of the predictors with an added error element. The method is built on the assumption that this error is normally distributed across all observations and has a mean of zero. In some cases, it has been found that the inherent variation is not the result of a random variable, but is instead the result of self-symmetric properties of the observations. For data with these …

Software Quality Control Through Formal Method, Jialiang Chang

Dissertations

With the improvement of theories in the software industry, software quality is becoming the most significant part of the procedure of software development. Due to the implicit and explicit vulnerabilities inside the software, software quality control has caught more researchers and engineers’ attention and interest.

Current research on software quality control and verification are involving various manual and automated testing methods, which can be categorized into static analysis and dynamic analysis. However, both of them have their own disadvantages. With static analysis methods, inputs will not be taken into consideration because the software system isn’t executed so we do not …

A Framework For Using Fused Image Data In Statistical Process Control, Shengfeng Chen

Dissertations

The use of image data in manufacturing quality control systems has grown rapidly over the years. Technological advancements in imaging devices (e.g., digital cameras, x-ray scanners, infrared cameras) have provided convenient and cost-effective ways to obtain images. These images contain important quality features (e.g., textures and product dimensions) that can be used to monitor, diagnose, predict, and control manufacturing processes. A key tool for monitoring images is statistical process control charts. Integrating images of parts to detect process shifts can significantly improve a quality systems efficiency. Unfortunately, appropriate techniques that take full advantage of data-rich images for control charting are …

Accumulation Of Polar Vorticity On Giant Planets: Towards A Three-Dimensional Theory, Shawn R. Brueshaber

Dissertations

My research investigates the polar atmospheric dynamics of the giant planets: Jupiter and Saturn (gas giants), and Uranus and Neptune (ice giants). I conduct my research modifying and applying the Explicit Planetary Isentropic Coordinate global circulation code to model the polar regions of the four giant planets.

The motivation behind my research is to uncover the reason why giant planet polar atmospheric dynamics differ. Jupiter features multiple circumpolar cyclones arranged in geometrical configurations, whereas Saturn features a single pole-centered cyclone. Uranus and Neptune also appear to have single pole-centered cyclones, albeit, larger than those on Saturn. …

Investigating Newly Discovered Oscillation Modes In Magnetically Shielded Hall Effect Thrusters Utilizing High Speed Diagnostics, Matthew Joseph Baird

Dissertations

Magnetically shielded Hall effect thrusters (MSHETs) are a variant of Hall effect thrusters (HET) that provide the favorable thrust-to-power ratio and high specific impulse of traditional stationary plasma type (STP) HETs but with an extremely long lifetime. MSHETs exhibit unique discharge plasma oscillations compared to traditional unshielded HETs. In this study, measurements of plasma oscillations in the state-of-the-art 12.5 kW Hall Effect Rocket with Magnetic Shielding (HERMeS) were obtained at various discharge voltages while holding other operation parameters constant. Data were collected using high-speed imaging, voltage, current, and plasma probes. The thruster exhibits two dominant oscillation modes within the discharge …

Attraction, Transport And Release Of Water Fleas’ Ephippia For Migration, Xiang Wang

Mechanical and Aerospace Engineering Dissertations - Archive

Planktonic crustaceans of the genus Daphnia live in aquatic environments. Although they are lack of walking and flying capabilities, they have developed adaptations that facilitate the dispersal of their dormant forms, ephippia to cross terrestrial barriers and reach neighborhood waterbodies. It increases the survival rate of their species. A possible way for this spread to occur is the transport of their ephippia through waterfowls’ legs. Yet, little is known about the key role of the legs in the dispersal and the main mechanisms. The ephippia first get attached to the waterfowls’ legs. The waterfowls may then carry these ephippia to …

Investigation Of The Impact Of Material Models On Reliability Assessment Of Electronic Packages, Abel Misrak

Mechanical and Aerospace Engineering Dissertations - Archive

Drop testing, thermal cycling, power cycling, etc. are some of the tests used to assess the reliability of new electronic products. However, performing experimental study of every new design is costly and time consuming. Computational tools are often employed to perform the required reliability analysis in a shorter time period and save valuable resources. Extensive set of material characterization work needs to be done before an accurate material model can be developed and used in computational analysis. Structural components such as printed circuit boards (PCBs) are critical in the thermomechanical reliability assessment of electronic packages. The bulk material properties of …

Sub-Modelling Approach For Computationally Efficient Thermal Simulations Of Large Li-Ion Battery Packs, Vishnu V. Ganesan

Mechanical and Aerospace Engineering Theses - Archive

Accurate and rapid prediction of temperature distribution in a large Li-ion battery pack comprising thousands of cells is critical for ensuring safety and performance of battery packs for electric vehicles (EVs). Due to the multiscale geometry and the large number of individual cells in an EV battery pack, full-scale thermal simulations typically take a long time to complete. Approaches for rapidly computing the temperature field in a large battery pack without significant loss of accuracy is, therefore, a key technological need. This paper presents thermal simulations of a large, air-cooled Li-ion battery pack containing thousands of individual cells using the …

Correlation And Effect Of Process Parameters On The Properties Of Inconel 718 Parts Fabricated By Selective Laser Melting Using Response Surface Method, Bharath Bhushan Ravichander

Mechanical and Aerospace Engineering Theses - Archive

Inconel 718 (i.e., IN718) is a nickel-based superalloy that exhibits outstanding tensile and impact-resistant properties, along with good high-temperature corrosion resistance. However, the machinability is poor due to the high stiffness of IN718. Therefore, additive manufacturing provides an effective solution to overcome the work hardening. Selective laser melting (SLM) is the most common powder-bed additive manufacturing technique designed to use a high power-density laser to melt and fuse the metallic powder to fabricate functional parts with high accuracy. However, the accuracy and the functional properties of the fabricated parts are greatly dependent on the process parameters. Thus, depending on the …

An Investigation On The Corrosion Inhibition Of Brazing Cu-Ag Alloy, Hooman Rahmani

Material Science and Engineering Dissertations - Archive

Adsorption and inhibition behavior of 1,2,3-benzotriazole (BTA) and 2,5-dimercapto-1,3,4-thiadiazole (DMTD) on brazing Cu-Ag alloy was studied in deionized water using corrosion potential measurement, potentiodynamic polarization, adsorption isotherm investigation, X-ray photoelectron spectroscopy (XPS), and electrochemical impedance spectroscopy (EIS). Pure Ag and pure Cu specimens were included to investigate the mere effect each component has on the alloy’s behavior along with a high copper alloy for comparison purposes. The electrochemical responses show that BTA shifts the corrosion potential of Cu to the noble direction but has the opposite effect for Ag and a mixed behavior for the Cu-Ag alloys. However, DMTD in …

Aqueous Redox Flow Batteries With Boron Doped Diamond As An Electrode., Alex M. Bates

Electronic Theses and Dissertations

As the interest and implementation of renewable energy accelerates, so does that of grid energy storage. It is widely believed that a cost-effective energy storage technology will bring about the proliferation of renewable energy. Redox flow battery (RFB) technology represents a promising solution to cost-effective grid energy storage. Compared to other technologies, RFBs have a long lifetime, high efficiency, are non-flammable, significantly reduce cost, and separately scale power and energy. The separation of power and energy enables increased energy capacity by simply adding electrolyte volume. Of the challenges facing RFB technology, one readily apparent is the cost of the active …

Formation Control Using Vehicle Operational Envelopes And Behavior-Based Dual-Mode Model Predictive Control, Brian Merrell

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This thesis presents a control framework for formation control. Given an initial desired trajectory, a framework is presented to generate trajectories for each vehicle within the formation. When combined with an operational envelope, a designated area for each vehicle to maneuver, for each vehicle the multi-vehicle formation control problem can be redefined into a single vehicle problem. A single vehicle framework is presented to track the respective trajectory when possible, or stay near it when it passes through previously unknown obstacles. Arc-based motions are used to rapidly produce desirable robot controls while a trajectory tracking motion is used to ensure …

Protecting Crops From Abiotic Stress: Copper Oxide Nanoparticle Effects On Wheat And A Beneficial Rhizobacterium, Matthew Potter

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Nanoparticles (NPs) are defined as particles less than 100 nm in at least one dimension. CuO NPs have possible applications in agriculture as micronutrient sources, pesticides, and enhancers of crop stress tolerance. Here, three aspects of CuO NP agricultural applications are studied: 1) the potential of CuO NPs to prevent wheat lodging-when crops irreversibly fall over; 2) CuO NP-induced drought tolerance in wheat seedlings; and 3) the effects of CuO NPs on outer membrane vesicle (OMV) production by Pseudomonas chlororaphis O6 (PcO6), a plant-health promoting bacterium.

Wheat grown 7 d exposed to CuO NPs in the growth matrix …

Development Of A Cvd Assisted Pld System For Growing Novel Materials, Sinjan Majumder

Graduate Theses/Dissertations

The fundamental step for development of novel materials like semiconductors involves stacking of layers of thin films of materials with desired properties on a particular substrate. In order to study the properties of these materials for research purposes in the laboratory, development of a clean fabrication technique is essential. PLD is a technique employed for growing thin films using laser ablation of a target material. CVD is an alternate method used to deposit solid materials from a gaseous phase. However, combining these two techniques can enhance plume, gas and laser interaction to facilitate the growth of novel materials with new …