Engineering Commons^™

Methods For The Discovery Of Antibodies Toward Junin Virus Utilizing Yeast Surface Display, Jonathon E. Corral

Doctoral Dissertations and Projects

The importance of this study is to perform antibody discovery as a means to derive novel preventative and therapeutic antibody countermeasures against the Junín virus, to alleviate the potential risk of a global pandemic. The purpose of this methodological study was to develop a protocol that utilizes yeast surface display to discover antibodies, from naïve human antibody libraries, that can bind the Junín Virus antigen. The methodology of yeast surface display employs the galactose-inducible GAL1 promoter to synthesize and express antibody proteins bound to the Aga2p and Aga1p and anchored to the cell wall by glycosyl phosphatidylinositol motif (GPI). The …

Development Of An Iot-Based Energy Theft Detection System For A Single-Phase Smart Meter, Ojo Julius Oladele, Funso Kehinde Ariyo, Samson Oladayo Ayanlade, Ayooluwa Peter Adeagbo, Ismail Adeniyi Adeleke

Al-Bahir

Electricity theft causes annual global losses exceeding $96 billion, severely impacting distribution networks. This paper presents a novel IoT-based system integrating current differential sensing, physical tamper detection, and edge-cloud analytics to detect energy theft in single-phase smart meters. The design employs three ACS712 current sensors to monitor Kirchhoff-compliant current flow at the grid pole, meter input, and load output, coupled with a PIR sensor for cabinet intrusion. A SIM800L GSM module enables real-time theft alerts and remote disconnection, while closed-loop control autonomously restores power after tamper resolution — a feature absent in prior GSM-only systems. An Android application provides geotagged …

Information Management / Bim Technology Evaluation Methodology, Robert Moore

Tools

This technology evaluation method provides a structured and transparent approach for assessing digital tools that support Information Management and Building Information Modelling (BIM). It establishes consistent criteria for evaluating functionality, interoperability, usability, compliance with standards such as ISO 19650, and alignment with organisational needs. The method supports objective comparison, informed decision-making, and proportionate investment, ensuring that technology acts as an enabler of defined processes rather than a driver in itself. Overall, it helps organisations select and implement technology solutions that are fit for purpose, scalable, and supportive of long-term Information Management / BIM adoption and continuous improvement.

Lattice Thermal Transport Beyond The Quasiparticle Approximation: Nontrivial Spectral Competition Between Three- And Four-Phonon Interactions, Yi Xia

Mechanical and Materials Engineering Faculty Publications and Presentations

The breakdown of the quasiparticle approximation (QPA) for phonons in strongly anharmonic materials necessitates advanced first-principles frameworks for accurate lattice dynamics and thermal transport predictions. We develop a comprehensive beyond-quasiparticle approximation (BQPA) approach incorporating both three- (3ph) and four-phonon (4ph) interactions and apply it to investigate lattice thermal conductivity (κL) in MgO, PbTe, and AgCl – materials that span a broad spectrum of anharmonicity, from weak to severe anharmonic regimes with overdamped phonons. We reveal that while BQPA consistently increases κL relative to QPA due to phonon softening when considering only 3ph interactions, the inclusion of additional 4ph interactions hardens …

Information Management / Bim Public Sector Adoption Business Case, Robert Moore

Tools

This business case sets out the value of adopting Information Management and BIM in line with ISO 19650 and the Irish CWMF. It shows how a structured approach to managing information across the asset lifecycle can improve collaboration, reduce risk and rework, and deliver measurable returns on investment. Evidence indicates that early adoption delivers the greatest benefit, supporting better cost control, compliance, and long-term asset performance. Overall, Information Management and BIM are positioned as essential enablers for efficient, sustainable, and future-ready delivery of public works

Information Management / Bim Technology Deployment Strategy, Robert Moore

Tools

This technology deployment strategy sets out a coordinated approach for implementing and rolling out digital tools to support Information Management and Building Information Modelling (IM/BIM). It focuses on aligning technology deployment with agreed processes, governance, and user capability, ensuring systems are configured, tested, and adopted effectively. The strategy emphasises phased deployment, risk management, training, and support, enabling organisations to embed technology in a controlled and sustainable manner. Overall, it provides a clear framework for turning selected technologies into reliable, value-adding enablers of consistent, standards-aligned IM/BIM delivery.

Puf-Based Digital Money With Propagation-Of-Provenance And Offline Transfers Between Two Parties, Benjamin Bean, Cyrus Minwalla, Eirini Eleni Tsiropoulou, Jim Plusquellic

Electrical and Computer Engineering ETDs

Building on prior concepts of electronic money (eCash), we introduce a digital currency where a physical unclonable function (PUF) engenders devices with the twin properties of being verifiably enrolled as a member of a legitimate set of eCash devices and possessing of a hardware-based root-of-trust. A hardware-obfuscated secure enclave (HOSE) is proposed as a means of enabling a PUF-based propagation-of-provenance (POP) mechanism, which allows eCash tokens (eCt) to be securely signed and validated by recipients without incurring any third party dependencies at transfer time. The POP scheme establishes a chain of custody starting with token creation, extending through multiple bilateral …

Methodological Approaches For Enhancing The Energy Efficiency Of Waste-To-Energy Biogas Systems, Evan Walls

Undergraduate Honors Theses

Diversifying the sources of energy production is a key issue as the world looks to transition to more sustainable energy sources. Anaerobic digestion (AD) of organic waste is one example of waste-to-energy (WTE) methods for energy production that is of particular interest in this clean energy transition because of benefits to both waste management and energy production, supporting the development of circular economies. In this work, I used geographic information systems and experimental methods to identify ways to both minimize the energy inputs and maximize the energy production of WTE biogas systems, to create energy efficient and sustainable systems. I …

2d-Nanosilicate Carriers For Sustained Delivery Of Vaccine Components, Chih Yun Liu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Laponite® 2D Nanosilicates (NS) are disc-shaped platelets (~30 nm diameter, ~1 nm thick) with positively charged edges and negatively charged faces, capable of loading proteins, drugs, and nucleic acids via electrostatic interactions to form a house-of-cards gel that sequesters cargo. Here, we evaluated NS for sustained delivery of antigens and Toll-like receptor (TLR) agonists to extend germinal center duration and enhance antibody quality. The model antigen ovalbumin (OVA) was adsorbed onto NS at acidic pH in a ~1:1 ratio, with partial unfolding that remained stable at physiological pH. NS-OVA complexes were efficiently internalized by dendritic cells, with uptake driven primarily …

Information Management / Bim Private Sector Adoption Business Case, Robert Moore

Tools

This business case sets out the rationale for adopting Information Management and Building Information Modelling (IM/BIM) within the private sector, aligned with ISO 19650. It explains how a structured, standards-based approach to managing information across the project lifecycle can reduce risk, improve coordination, and protect commercial margins by minimising rework, late changes, and delays. The document highlights that early and targeted investment in people, processes, and digital tools delivers the greatest return, supporting faster approvals, clearer decision-making, more competitive bids, and consistent project delivery. Overall, the business case positions IM/BIM as a practical enabler of productivity, resilience, and long-term competitiveness …

Characterizing Temperature-Dependent Properties Of Fat For Improving High Intensity Focused Ultrasound Simulations, Brian Easthope

Theses and Dissertations

High-intensity focused ultrasound (HIFU) is a non-invasive therapeutic technique that relies on the precise delivery of acoustic energy to ablate diseased tissue. The presence of subcutaneous fat can significantly alter focal accuracy and treatment efficiency due to its distinct thermal and acoustic behavior. This study characterized the temperature-dependent thermal conductivity, thermal diffusivity, specific heat capacity, acoustic attenuation, and acoustic velocity of human subcutaneous fat to improve pretreatment modeling for HIFU therapies. Measurements were performed using a dual needle probe for thermal conductivity and diffusivity, differential scanning calorimetry for specific heat capacity, radiation force balance for attenuation, and through-transmission methods for …

Measuring And Modeling Nonlinear Vibrations In Structures With Mechanical Joints, Suzanna Gilbert

Theses and Dissertations

Many assembled structures have bolted or riveted joints. Aside from providing a convenient method of assembly, mechanical joints have an important effect on the structure's dynamic response to its environment. Friction and microslip within the joints help to damp out unwanted vibration. However, the joints also introduce nonlinearity into the response. Most notably, the natural vibrational modes of the structure no longer have constant natural frequencies and damping ratios. Rather, they shift as a function of vibration amplitude. Several methods exist to characterize the dynamics of nonlinear systems, yet they are generally validated on simple benchmark structures, and many still …

Information Management / Bim Adoption Plan, Robert Moore

Tools

This adoption plan translates the Information Management and BIM adoption strategy into a clear, actionable programme of work. It sets out the specific activities, responsibilities, and sequencing required to build capability across people, processes, and technology, supporting consistent implementation in line with ISO 19650 and organisational objectives. The plan enables progress to be managed, monitored, and reviewed over time, ensuring adoption is proportionate, achievable, and aligned with project and business needs. Overall, it provides a practical mechanism for moving from intent to delivery, embedding Information Management and BIM as standard practice within the organisation.

Information Management / Bim Technology Deployment Plan, Robert Moore

Tools

This technology deployment plan sets out the practical steps required to implement and operationalise selected Information Management and BIM (BIM) technologies. It defines activities, responsibilities, sequencing, and dependencies to ensure systems are configured, tested, and adopted in a controlled and coordinated manner. The plan supports effective change management, training, and transition to business-as-usual use, reducing risk and disruption. Overall, it provides a clear, actionable framework for moving from technology selection to consistent, reliable use that supports standards-aligned Information Management / BIM delivery.

Information Management / Bim Adoption Strategy, Robert Moore

Tools

This adoption strategy sets out a structured approach for organisations to plan, govern, and deliver the adoption of Information Management and Building Information Modelling (IM/BIM). It focuses on aligning leadership intent with clear objectives, defined actions, and measurable outcomes, ensuring that people, processes, and technology are developed in a coordinated way. The strategy supports a phased and proportionate approach to adoption, enabling organisations to build capability over time, respond to client and market requirements, and embed continuous improvement. Overall, it provides a clear framework for translating strategic intent into practical, repeatable actions that support consistent, standards-aligned delivery and long-term organisational …

Information Management / Bim Adoption And Implementation Roadmap, Robert Moore

Tools

This roadmap sets out a clear, practical approach for organisations to adopt and implement Information Management and Building Information Modelling (IM/BIM) in line with ISO 19650 and the Capital Works Management Framework (CWMF). It provides a phased pathway from early capacity to advanced capability, showing how organisations can progressively build skills, processes, and digital workflows while meeting the requirements of the Irish BIM mandate. The roadmap aligns organisational change with project-level delivery, emphasising the foundations of people, process, and technology, and the importance of collaboration, governance, and continuous improvement. Overall, it supports organisations in moving from basic information management to …

Uniclass Irish Bim Mandate Guide, Robert Moore

Tools

This guidance document provides practical direction on implementing Uniclass within Irish public sector projects to support the Capital Works Management Framework (CWMF) BIM mandate. It explains how Uniclass, used alongside ISO 19650, IFC, and ICMS, enables consistent classification of information across the asset lifecycle, supporting the creation of a reliable golden thread of data from design through to operation. The document sets out how Uniclass works in practice, clarifying roles and responsibilities, common challenges, and mitigation measures, and includes a worked examples to support consistent application. Overall, the guide positions Uniclass as a key enabler of structured information management, improved …

Computational Study Of Cavitation In An Inducer Pump, Jaylen Leonard

UNLV Theses, Dissertations, Professional Papers, and Capstones

Cavitation is ubiquitous in liquid-handling turbomachines. Cavitation bubbles form when the local pressure drops below a fluid’s vapor pressure, and their subsequent collapse causes implosions that generate shockwaves and microjets. These effects lead to fluid instability and structural damage to the blades and casing in turbomachines. This thesis investigates this cavitation phenomenon in turbomachines using Computational Fluid Dynamics (CFD). The cavitation model built in ANSYS Fluent® is first validated in a venturi tube model and then applied to an inducer pump. The geometry of the pump is derived from the Space Shuttle Main Engine (SSME) Low Pressure Oxidizer Pump (LPOP) …

Design And Development Of Biomimetic Hydrogel Interfaces For Enhanced Bioelectrical Signal Acquisition, Daniela Nikoloska

UNLV Theses, Dissertations, Professional Papers, and Capstones

Every second, human skin processes over one million sensory signals while maintaining properties such as electrical conductivity, mechanical adaptability, and regenerative capability that surpass all synthetic materials. Contemporary bioelectronic devices prove inadequate when contacting skin surfaces due to poor adhesion and electrical contact issues that prevent effective sensing. Despite advancements in wearable and bioelectronic technologies, current devices face major drawbacks when interfacing with human skin, particularly in maintaining firm adhesion, conformability, and low-noise electrical signal acquisition.

This research focuses on the development of a biomimetic hydrogel-based interface for bioelectronic sensing. Specifically, a hybrid hydrogel system composed of polydopamine (PDA)- doped …

Inelastic Behavior Of Three-Story Buildings With Concrete-Filled Composite Plate Shear Walls Subjected To Wind Loads, Joshua John Blom

Theses and Dissertations

Although elastic design of the main wind force resisting system in a building is the conventional approach it is not always desirable. In this study, nonlinear static and dynamic analyses are used to predict the inelastic behavior of a three-story building with concrete-filled composite plate shear walls subjected to wind loads. To explore the potential for inelastic design, two types of planar composite shear wall buildings are examined: individual shear walls designed using an elastic approach, and coupled shear wall pairs designed using an inelastic approach adopted from seismic design provisions. Nonlinear static "pushover" analyses are run using an assumed …

Experimental Testing Of Axially Loaded Fuse Plates Without Continuous Buckling Restraint, Rebekah Elizabeth Higgins

Theses and Dissertations

Current seismic design practice is to design structures to avoid collapse and protect life. Buildings are designed to resist seismic loading through strength and ductility. In moment frames, this ductility traditionally comes from inelastic deformation of beams. Moment frame connections move inelastic deformation away from the column and allow a plastic hinge to form in the beam. This plastic hinge prevents collapse but leaves the building difficult to repair. Some proprietary moment frame connections address this issue with replaceable fuse plate connections. These fuse plate connections move the plastic hinge out of the beam and into the replaceable fuse, allowing …

Applied Research In Field Crop Pathology For Indiana, 2022, Darcy E. P. Telenko, Sujoung Shim

Purdue University Press Books

Applied Research in Field Crop Pathology for Indiana, 2022 serves as a summary of the applied field crop pathology research trials conducted in 2022 under the direction of the Purdue Field Crop Pathology program in the Department of Botany and Plant Pathology at Purdue University. In Indiana, there are more than 57,600 farms, 16,000 crop producers, and 900 certified crop advisers, Extension educators, and crop-protection industry representatives who manage more than 11.4 million crop-production acres with a total value of $6.3 billion annually. There are more than twenty diseases affecting corn, soybeans, and wheat that may decrease crop production and …

Fundamental Hydraulics Principles For Agricultural Systems Management And Technology, Robert M. Stwalley Iii, Roger Tormoehlen

Purdue University Press Books

Hydraulic systems have spread throughout modern technology, particularly in mobile equipment. The exercises presented in Fundamental Hydraulic Principles for Agricultural Systems Management and Technology are designed for the second-generation Parker Hydraulic Trainer to provide a basic understanding of hydraulic components and systems for technology and engineering students. Readers will learn how hydraulic pumps function, how linear actuators and their control circuits work, and how hydraulic motors operate and are controlled. Readers are also provided with the opportunity to attempt more advanced exercises. Aligned with beginning technology-based experiential hydraulics courses, this book emphasizes familiarity with common hydraulic components and circuit diagrams, …

Applied Research In Field Crop Pathology For Indiana, 2021, Darcy E. P. Telenko, Sujoung Shim

Purdue University Press Books

Applied Research in Field Crop Pathology for Indiana, 2021 serves as a summary of the applied field crop pathology research trials conducted in 2021 under the direction of the Purdue Field Crop Pathology program in the Department of Botany and Plant Pathology at Purdue University. In Indiana, there are more than 57,600 farms, 16,000 crop producers, and 900 certified crop advisers, Extension educators, and crop-protection industry representatives who manage more than 11.4 million crop-production acres with a total value of $6.3 billion annually. There are more than twenty diseases affecting corn, soybeans, and wheat that may decrease crop production and …

Stability Analysis Of Thermohaline Convection With A Time-Varying Shear Flow Using The Lyapunov Method, Kalin Kochnev

Honors Scholar Theses

This work applies the Lyapunov method to identify instabilities and compute the growth rate of a linear time-varying system. The linear system studied describes cold fresh water on top of hot salty water with a periodically time-varying background shear flow. A time-dependent weighting matrix is employed to construct a Lyapunov function candidate. The resulting linear matrix inequalities are discretized in time using the forward Euler method. As the number of temporal discretization points increases, the growth rate predicted by the Lyapunov method or Floquet theory, used for comparison, will converge to the same value obtained from numerical simulations. Furthermore, the …

Analysis Of Leakage In Nearshore Pipelines Using Fitness For Service Method To Ensure Mechanical Integrity Based On Api-579 Level 3, Elriandri Elriandri, Dedi Priadi

Journal of Materials Exploration and Findings

The Fitness for Service (FFS) analysis is performed as a quantitative assessment to evaluate the integrity condition of a pipeline. Essentially, FFS assessment helps determine whether equipment components can operate safely despite existing deficiencies. This evaluation is carried out using the Finite Element Method (FEM). In the case of an underwater pipeline that experiences leak due to anchor pull at the flange connection, it undergoes plastic deformation and is lifted approximately 1 meter. As a mitigation step, inspection and repairs have been carried out by the company. Subsequently, modeling is performed to reconstruct the deformation process of the pipeline. Then, …

Assessment Of The Melt Quality Of A 30% Scrap Adc12 Aluminium Alloy Using The Inclusion And Fluidity Measurement Instrument (Ifmi) With Mullite Ceramic Filters, Gusti Ruri Ruri Lestari, Sandya Ananda Riswan, Muhammad Anis, Ahmad Ashari, Paramita Vidya Ayuningtyas, Bambang Suharno Prof, Donanta Dhaneswara

Journal of Materials Exploration and Findings

The increasing demand for sustainable practices in the metal casting industry has driven the use of recycled aluminum alloys such as ADC12. However, the addition of aluminum scrap tends to increase oxide inclusions, which reduce melt fluidity and compromise casting quality. This study utilizes the Inclusion and Fluidity Measurement Instrument (IFMI), equipped with mullite ceramic filters, to assess the melt quality of ADC12 aluminum alloy containing 30% scrap. Fluidity and inclusion characteristics were evaluated at five pouring temperatures (660°C, 680°C, 700°C, 720°C, and 740°C). The results show that fluidity increased with temperature, reaching a peak of 84.6 g·s⁻¹ at 740°C, …

Equipment Criticality Analysis To Determine Asset Integrity Management System Scheme In Supporting Production Optimization Scenarios In The Aeging Field, Donny Andryanto, Donanta Dhaneswara

Journal of Materials Exploration and Findings

This research investigates the production decline and cost increase in the X&Y oil and gas fields from 2022 to 2023. Production fell by 34%, while production costs per barrel rose by 79%. To address these issues, a series of optimization processes are proposed. These aim to restructure and enhance the production facilities to reduce current production costs. The optimizations include reducing pressure at the PPP Platform in 2024. Additional steps include shutting down CPP-ORF 14” pipelines and most processes at CPP 2 Platform by 2027 to convert it into an accommodation platform. Further, the plan involves optimizing the release of …

Identification Safety Critical Elements And Establish Performance Standards To Control Major Accident Hazard At The Geothermal Power Plant Pt. Xyz, Febriardy Febriardy, Jaka Fajar Fatriansyah, Endang Endang, Farhan Iqbal Bagaskoro, Ari Kurniawan

Journal of Materials Exploration and Findings

Geothermal Power Plant (GPP) use steam from geothermal reservoirs to produce electricity. Power Plants are one of the most dangerous work environments. The dangers that exist in the power generation process can be in the form of Major Accident Hazard (MAH) and have a large impact which can cause Major Accidents. Major Accident prevention can be done by managing Safety Critical Elements (SCE) as a control measure in the form of procedures to prevent or mitigate the risks. Each SCE has a Performance Standard that includes targets and thresholds set to reduce risk to reach ALARP (As Low as Reasonably …

An Overview Of Biomass-Derived Graphene Oxide And Its Characteristics For Future Sustainable Applications, Afif Wardana, Ahmad Nabil Shahab, Donanta Dhaneswara, Nofrijon Sofyan

Journal of Materials Exploration and Findings

The production of graphene oxide (GO) from biomass presents considerable promise as a sustainable alternative substitute for traditional semiconductors. Biomass waste, abundant and often underutilized worldwide, is distinguished by its high carbon content and regenerative characteristics, rendering it an optimal resource for sustainable material production. By heating its biopolymers, lignocellulosic biomass can be used as a new material to make graphene, which forms three-dimensional turbostratic crystallites. These crystallites, composed of partially defective aromatic carbon sheets with graphite-like characteristics, make it easier to create GO with specialized functions for cutting-edge applications. Its capability underscores the revolutionary potential of biomass waste in …