Engineering Commons^™

The Role Of Son In Chromatin-Mediated Gene Expression, Melissa Jordan Ward

Browse all Theses and Dissertations

Gene expression in mammalian cells requires complex nuclear choreography, and there is increasing evidence that spatiotemporal organization of chromatin and nuclear compartments plays an important role in gene expression. In this dissertation, I examined the function of SON, a splicing factor with a known role in nuclear organization, in chromatin-mediated gene expression. SON association with a transcriptionally inactive U2OS 2-6-3 reporter gene array provided a useful model to study SON’s chromatin dynamics. I demonstrated that SON associates with the inactive but not the activated array, and that SON’s RNA binding domains are not necessary for that association. Second, I discovered …

Effects Of Additive Manufacturing Techniques On The Magnetocaloric Properties And Chemical Stability Of Lafexcoysi13-X-Y Alloys, Binyam Wodajo

Theses and Dissertations

Additive manufacturing (AM) is an emerging process to fabricate net shape, intricate, engineering components with minimal material waste; however, traditionally it has been largely applied to structural materials. AM of functional materials, such as magnetic materials, has received much less attention and the field is still in its infancy. To date, AM of magnetocaloric regenerators for magnetic refrigeration (an energy-efficient alternative to the conventional vapor-compression cooling technology), remains a challenge. There are several magnetic refrigerator device designs in existence today that are predicted to be highly energy-efficient, on condition that suitable working materials can be developed. This challenge in manufacturing …

Publishing Toolkit For Early Career Academics I And Ii: Lublin Institute Of Technology, April 27, 2022 And May 4, 2022, Sue Ann Gardner

University of Nebraska-Lincoln Libraries: Presentations

Summary

Covers knowledge required of early career academics to create and submit academic publications. A broad range of concerns are addressed covering the entire lifecycle of scholarship including discussion dissertations, considering how to determine where to submit works, preparing and submitting manuscripts, and how to ensure that works are made available openly. The emphasis is on scholarly articles prepared for publication in academic journals, but alternate forms of scholarly communication are also discussed, including posters, conference presentations, computer code, and datasets. Includes a list of supplemental resources for further learning.

Data Science Applied To Discover Ancient Minoan-Indus Valley Trade Routes Implied By Commonweight Measures, Peter Revesz

School of Computing: Conference and Workshop Papers

This paper applies data mining of weight measures to discover possible long-distance trade routes among Bronze Age civilizations from the Mediterranean area to India. As a result, a new northern route via the Black Sea is discovered between the Minoan and the Indus Valley civilizations. This discovery enhances the growing set of evidence for a strong and vibrant connection among Bronze Age civilizations.

Infrared Dielectric Functions And Brillouin Zone Center Phonons Of Α-Ga2O3 Compared To Α-Al2O3, Megan Stokey, Rafal Korlacki, Matthew J. Hilfiker, Sean Knight, Steffen Richter, Vanya Darakchieva, Riena Jinno, Yongjin Cho, Huili Grace Xing, Debdeep Jena, Yuichi Oshima, Kamruzzaman Khan, Elaheh Ahmadi, Mathias Schubert

Department of Electrical and Computer Engineering: Faculty Publications

We determine the anisotropic dielectric functions of rhombohedral α-Ga₂O₃ by far-infrared and infrared generalized spectroscopic ellipsometry and derive all transverse optical and longitudinal optical phonon mode frequencies and broadening parameters. We also determine the high-frequency and static dielectric constants. We perform density functional theory computations and determine the phonon dispersion for all branches in the Brillouin zone, and we derive all phonon mode parameters at the Brillouin zone center including Raman-active, infrared-active, and silent modes. Excellent agreement is obtained between our experimental and computation results as well as among all previously reported partial information from experiment …

Serum Protein Signatures Using Aptamer-Based Proteomics For Minimal Change Disease And Membranous Nephropathy, Daniel A. Muruve, Hanna Debiec, Simon T. Dillon, Xuesong Gu, Emmanuelle Plaisier, Handan Can, Hasan H. Otu, Towia A. Libermann, Pierre Ronco

Department of Electrical and Computer Engineering: Faculty Publications

Introduction: Minimal change disease (MCD) and membranous nephropathy (MN) are glomerular diseases (glomerulonephritis [GN]) that present with the nephrotic syndrome. Although circulating PLA2R antibodies have been validated as a biomarker for MN, the diagnosis of MCD and PLA2R-negative MN still relies on the results of kidney biopsy or empirical corticosteroids in children. We aimed to identify serum protein biomarker signatures associated with MCD and MN pathogenesis using aptamer-based proteomics.

Methods: Quantitative SOMAscan proteomics was applied to the serum of adult patients with MCD (n = 15) and MN(n = 37) and healthy controls (n = …

Type Iii And Iv Deformation Twins In Minerals And Metals, John P. Hirth, Greg Hirth, Jian Wang

Department of Mechanical and Materials Engineering: Faculty Publications

Type IV twins are defined and shown to exist in triclinic crystal systems, as well as in some monoclinic and trigonal systems. Here, we focus on Pericline twins in triclinic plagioclase as an example. Type IV twins are associated with the irrationality of one of the twinning elements that is rational for a type II twin. The formation of type IV twins is accomplished through the shear on a K2 plane produced by the motion of twinning disconnections on a K1 plane, followed by rotational partitioning. The same systems where type IV twins are present also have type III twins …

Emissivity Prediction Of Functionalized Surfaces Using Artificial Intelligence, Greg Acosta, Andrew Reicks, Miguel Moreno, Alireza Borjali, Craig Zuhlke, Mohammad Ghashami

Department of Mechanical and Materials Engineering: Faculty Publications

Tuning surface emissivity has been of great interest in thermal radiation applications, such as thermophotovoltaics and passive radiative cooling. As a low-cost and scalable technique for manufacturing surfaces with desired emissivities, femtosecond laser surface processing (FLSP) has recently drawn enormous attention. Despite the versatility offered by FLSP, there is a knowledge gap in accurately predicting the outcome emissivity prior to fabrication. In this work, we demonstrate the immense advantage of employing artificial intelligence (AI) techniques to predict the emissivity of complex surfaces. For this aim, we used FLSP to fabricate 116 different aluminum samples. A comprehensive dataset was established by …

Construction Of A Peridynamic Model For Viscous Flow, Jiangming Zhao, Adam Larios, Florin Bobaru Ph.D.

Department of Mechanical and Materials Engineering: Faculty Publications

We derive the Eulerian formulation for a peridynamic (PD) model of Newtonian viscous flow starting from fundamental principles: conservation of mass and momentum. This formulation is different from models for viscous flow that utilize the so-called “peridynamic differential operator” with the classical Navier- Stokes equations. We show that the classical continuity equation is a limiting case of the PD one, assuming certain smoothness conditions. The PD model for viscous flow is calibrated to the classical Navier-Stokes equations by enforcing linear consistency for the viscous stress term. Couette and Poiseuille flows, and incompressible fluid flow past a regular lattice of cylinders …

Ultrathin Coding Metasurface For Underwater Wave Focusing, Branching And Self-Bending Generation With One Single Actuator, Lixie Song, Zhong Chen, Mehrdad Negahban, Lei Liang, Zheng Li, Zheng Wu

Department of Mechanical and Materials Engineering: Faculty Publications

A novel metasurface is proposed that aims to generate underwater acoustic waves with various functions by only one actuator. Each metasurface unit consists of an air cavity sandwiched on one side by a vibration plate and connecting rubber supports. By properly selecting the ratio of the plate to unit lengths, a phase shift of π can be attained to constitute a binary coding metasurface. Three demonstrations, including focusing, branching and self-bending waves, are chosen to validate the functionality of the design. The design is also shown to work over a wide frequency range through changing the ratio. In addition, the …

Machine Learning Assisted Metamaterial‑Based Reconfigurable Antenna For Low‑Cost Portable Electronic Devices, Shobhit K. Patel, Jaymit Surve, Vijay Katkar, Juveriya Parmar

Department of Mechanical and Materials Engineering: Faculty Publications

Antenna design has evolved from bulkier to small portable designs but there is a need for smarter antenna design using machine learning algorithms that can meet today’s high growing demand for smart and fast devices. Here in this research, main focus is on developing smart antenna design using machine learning applicable in 5G mobile applications and portable Wi-Fi, Wi-MAX, and WLAN applications. Our design is based on the metamaterial concept where the patch is truncated and etched with a split ring resonator (SRR). The high gain requirement is met by adding metamaterial superstrates having thin wires (TW) and SRRs. The …

Symmetric Or Asymmetric Glide Resistance To Twinning Disconnection?, Mingyu Gong, Houyu Ma, Kunming Yang, Yue Liu, Jian-Feng Nie, Jian Wang

Department of Mechanical and Materials Engineering: Faculty Publications

Successive gliding of twinning disconnections (TDs) creates three-dimensional twins in parent crystal and accommodates shear deformation. It is generally recognized that TD is subject to the same Peierls stress as it glides forward or backward because of its dislocation character and the twofold rotation symmetry of the twin plane. Based on atomistic simulations, we demonstrate that the glide of TDs may be subject to a symmetric or asymmetric resistance corresponding to step character, symmetric resistance for A/A type steps but asymmetric resistance for A/B type steps, where A and B represent crystallographic planes in twin and matrix. Furthermore, we experimentally …

Pilot-Scale Spinning And Sucrose-Tetra-Aldehydes-Crosslinking Of Feather-Derived Protein Fibers With Improved Mechanical Properties And Water Resistance, Bingnan Mu, Faqrul Hassan, Qianmei Wu, Yiqi Yang

Department of Textiles, Merchandising and Fashion Design: Faculty Publications

Pliable and water-resistant protein fibers from feathers were developed via continuous one-step spinning and crosslinking using sucrose-tetra-aldehydes. Though flexible protein fibers from feathers were developed, poor wet stability and low tenacity still limit the large and high-end applications of feather-derived fibers. Despite that saccharide aldehydes are considered as an efficient and sustainable crosslinker, substantial concerns such as generation of formaldehyde, high consumption of modifiers, loss of mechanical properties, yellowing, and decline in dyeability of fibers, exist after crosslinking. In this work, we controlled structures of crosslinkers and incorporated disaccharide-tetra-aldehydes into a continuous wet-spinning line. No formaldehyde was generated in the …

Evaluating The Factors Influencing Alignment Of It And Business In A Cloud Computing Environment, Dr. Shailja Tripathi

Journal of International Technology and Information Management

Aligning IT with business strategically is the recent area of attention among researchers and practitioners because of its potential impact on organizational performance. Currently, large numbers of enterprises are migrating towards cloud computing as on-premise implementation of Information technology (IT) infrastructure is expensive. The purpose of this research is to examine the factors that influence the alignment of IT and business in cloud computing environment. Therefore, this study used the Strategic Alignment Maturity (SAM) model as a framework to validate the evolution of IT-business alignment in a cloud computing platform. A questionnaire-based survey method was employed for data collection. The …

Will Products Liability Litigation Help Protect Iot Users From Cyber-Physical Attacks?, J Royce Fichtner, Troy J. Strader

Journal of International Technology and Information Management

While there is an identifiable trend towards protecting consumers from data breaches and data misuses related to IoT devices through new legislation, new regulations, government enforcement actions, and private lawsuits, there has been little progress towards creating similar legally enforceable standards of care for “cyber-physical device security.” This article explores this underdeveloped area of academic inquiry into cyber-physical device security within the context of product liability litigation in the United States. The two questions addressed in this article are: (1) Have there been any successful products liability court decisions in the United States that have held IoT manufacturers liable for …

E-Payment Adoption In Saudi Arabia, Alexander N. Chen, Joseph Y. Thomas, Mark E. Mcmurtrey Ph.D., Michael E. Ellis

Journal of International Technology and Information Management

Internet technology has influenced banking systems because of its capability to enhance the performance of financial operations. Several factors influence the adoption of new technology within the financial industry. Namely the customers’ perception of benefit, quality, Ease of Use, Security, Self-Efficacy, and Trust. However, various cultures and geopolitical issues influence technology adoption and are therefore worth further study. This paper focuses on the factors that influence the behaviors of Saudi Arabians and their adoption of e-payment systems. The paper shows the fundamental discoveries of an investigation examining the dispersion and the adoption of e-payment technology in …

Examining Factors Influencing Intention To Use M-Health Applications For Promoting Healthier Life Among Smartphone Users In Tanzania, Herman Mandari, Mahija Yahaya

Journal of International Technology and Information Management

Deaths related with Non-Communicable Diseases (NCDs) have recently increases, similarly, development of mobile technologies have paved a way in which Smartphone users can use m-health applications to address high level of sedentary behaviours that relates to negative health consequences. Therefore, this study was conducted to examine factors which may influence generation Y who are Smartphone users to adopt m-health applications in controlling NCDs in Tanzania. TAM theory was extended with awareness, trust and perceived cost to develop a research conceptual model of this study. Google form was used to developed online questionnaire which was distributed through social media platforms to …

Biodiesel Production From Castor Oil: Mixing Optimization During Transestrification, Islam M. Al-Akraa

Chemical Engineering

No abstract provided.

Valuable Biodiesel Catalyst From Solvay Wastewater, Mai Hassan Roushdy, Rana Adel Bayoumi

Chemical Engineering

Biodiesel is considered a renewable, green fuel as it is derived from renewable living resources like animal fats or vegetable oils. This research is utilized to investigate the possibility of using Solvay wastewater as a source of biodiesel catalyst, which is CaO. CaCl2 from Solvay wastewater reacts with CO2 to produce CaCO3. CaCO3 is then heated to produce pure CaO. Waste cooking oil, wastewater, and CO2, which are considered dangerous materials to the environment, are used to produce valuable products. This research has environmental and economic benefit benefits of using waste materials as a replacement for raw materials. The selected …

Biodiesel Production From Castor Oil: Mixing Optimization During Transesterification, Yaser M. Asal Mr, Islam M. Al-Akraa, Ahmad M. Mohammad, Hassan E. Hisham

Chemical Engineering

With the growing warning for accrediting the traditional combustion of fossil fuels for energy production, not only for their limited supply but also for their environmental risks (air pollution, climate change, …. etc), it became necessary to realize alternative greener and abundant sources for energy. Instead, the interest to sustain biodiesel for the energy production has recently been renewed as a replacement for petroleum diesel in conventional diesel engines. This was due to its renewable nature, low toxicity, high degradability and unique physical properties (high flash points & lubrication). Castor oil, in particular, appeared promising for biodiesel production with extremely …

A Competent Mwcnt-Grafted Mnox/Pt Nanoanode For The Direct Formic Acid Fuel Cells, Islam M. Al-Akraa, Ahmad M. Mohammad, Moutaz Mamdouh, Yasser M. Asal

Chemical Engineering

No abstract provided.

Resistome And Mobilome In Surface Runoff From Manured Soil As Affected By Setback Distance, Noelle Mware, Maria C. Hall, Selvakumar Rajendran, John E. Gilley, Amy Schmidt, Shannon Bartelt-Hunt, Yifan Zhang, Xu Li

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Land application of livestock manure introduces antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) into the soil environment. The objectives of this study were to examine the changes of resistome and mobilome in runoff and soil as a function of setback distance, i.e., the distance between manured soil and surface water, and to quantify the contributions of manure and background soil to the ARGs and MGEs in surface runoff. The resistome and mobilome in runoff and soil from a field-scale plot study were characterized using a high throughput quantitative polymerase chain reaction (HT-qPCR) array. It was estimated that a …

Emission Of Volatile Organic Compounds From Land-Applied Beef Cattle Manure As Affected By Application Method, Diet, And Soil Water Condition, Bryan L. Woodbury, John E. Gilley, David B. Parker, David B. Marx

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Land application of beef cattle manure may result in the emission of volatile organic compounds (VOC). This study was conducted to evaluate the effects of diet, land application method, soil water condition, and time since manure application on VOC emissions. Manure was collected from feedlot pens where cattle were fed diets containing 0%, 10%, or 30% wet distillers grains with solubles (WDGS). The effects of manure application method (surface-applied or incorporated) and soil water condition (saturated or wet) on VOC emissions were measured over a 48 h period. Heptanoic, hexanoic, isobutyric, and isovaleric acids contributed 23.5%, 17.6%, 9.26%, and 3.39% …

Geospatial Synthesis Of Biogeochemical Attributions Of Porphyrins To Oil Pollution In Marine Sediments Of The Gulf Of México, Francisco Muñoz-Arriola, José Vinicio Macías-Zamora

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Porphyrins are highly persistent in the environment and represent a helpful biogeochemical attribute to assess the spatial distribution of the effects of oil spills on ecosystems and their resilience. In areas prone to natural and human-originated oil spills, the measurement of VO– and nickel– porphyrins in marine–sediment samples can identify the effects of oil pollution across spatiotemporal scales. The goal is to explore whether or not these compounds can be useful indicators of the geospatial attributions of oil contamination in the surficial sediments. We hypothesize that the geospatial gradients of porphyrins in marine sediments from petroleum spills and seepage activities—related …

The Brazilian Soil Spectral Service (Braspecs): A User-Friendly System For Global Soil Spectra Communication, José A. M. Demattê, Ariane Francine Da Silveira Paiva, Raul Roberto Poppiel, Nícolas Augusto Rosin, Luis Fernando Chimelo Ruiz, Fellipe Alcantara De Oliveira Mello, Budiman Minasny, Sabine Grunwald, Yufeng Ge, Eyal Ben Dor, Asa Gholizadeh, Cecile Gomez, Sabine Chabrillat, Nicolas Francos, Shamsollah Ayoubi, Dian Fiantis, James Kobina Mensah Biney, Changkun Wang, Abdelaziz Belal, Salman Naimi, Najmeh Asgari Hafshejani, Henrique Bellinaso, Jean Michel Moura-Bueno, Nélida E. Q. Silvero

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Although many Soil Spectral Libraries (SSLs) have been created globally, these libraries still have not been operationalized for end-users. To address this limitation, this study created an online Brazilian Soil Spectral Service (BraSpecS). The system was based on the Brazilian Soil Spectral Library (BSSL) with samples collected in the Visible–Near–Short-wave infrared (vis–NIR–SWIR) and Midinfrared (MIR) ranges. The interactive platform allows users to find spectra, act as custodians of the data, and estimate several soil properties and classification. The system was tested by 500 Brazilian and 65 international users. Users accessed the platform (besbbr.com.br), uploaded their spectra, and received soil organic …

Unmanned Aerial System-Based Data Ferrying Over A Sensor Node Station Network In Maize, Jasreman Singh, Yufeng Ge, Derek M. Heeren, Elizabeth Walter-Shea, Christopher M. U. Neale, Suat Irmak, Mitchell S. Maguire

Department of Agricultural and Biological Systems Engineering: Faculty Publications

© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).

High Throughput Analysis Of Leaf Chlorophyll Content In Sorghum Using Rgb, Hyperspectral, And Fluorescence Imaging And Sensor Fusion, Huichun Zhang, Yufeng Ge, Xinyan Xie, Abbas Atefi, Nuwan Wijewardane,, Suresh Thapa

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Background: Leaf chlorophyll content plays an important role in indicating plant stresses and nutrient status. Traditional approaches for the quantification of chlorophyll content mainly include acetone ethanol extraction, spectrophotometry and high-performance liquid chromatography. Such destructive methods based on laboratory procedures are time consuming, expensive, and not suitable for high-throughput analysis. High throughput imaging techniques are now widely used for non-destructive analysis of plant phenotypic traits. In this study three imaging modules (RGB, hyperspectral, and fluorescence imaging) were, separately and in combination, used to estimate chlorophyll content of sorghum plants in a greenhouse environment. Color features, spectral indices, and chlorophyll fluorescence …

Maize Response To Irrigation And Nitrogen Under Center Pivot, Subsurface Drip And Furrow Irrigation: Water Productivity, Basal Evapotranspiration And Yield Response Factors, Ali T. Mohammed, Suat Irmak

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Information and data about quantification and comparison of crop water productivity indices for various irrigation levels and methods and nitrogen (N) application timings “simultaneously” under the same conditions do not exist. Unprecedented and extensive field experiments were conducted for maize (Zea mays L.) in 2016 and 2017 under center pivot (CP), subsurface drip irrigation (SDI) and furrow irrigation (FI) methods with full irrigation treatment (FIT), 80% FIT, 60% FIT and rainfed treatment (RFT) with three N application timings. N treatments were: (i) traditional (TN), (ii) non-traditional-1 (NT-1) and (iii) non-traditional-2 (NT-2). Irrigation yield production functions (IYPF); evapotranspiration-yield production functions …

Sources Of Variability And Uncertainty In Food-Energy-Water Nexus Systems, Heydi Calderon-Ambelis, Deepak R. Keshwani

Department of Agricultural and Biological Systems Engineering: Faculty Publications

A nexus approach contributes to the strategic allocation of resources to secure food, energy, and water for the world population. Integrated models considering the complex interactions across food, energy, and water (FEW) enhance decision-making and strategic planning towards resilience. However, a significant number of the existing integrated models leave unaddressed the inherent variability and uncertainty present in the FEW sectors. Here, we review the importance of characterizing variability over spatial and temporal scales and the importance of decreasing the uncertainty present within a FEW nexus systems. The review also discusses existing modeling tools that address variability and uncertainty on single …

Modeling Water Quantity And Quality Nonlinearities For Watershed Adaptability To Hydroclimate Extremes In Agricultural Landscapes, Juan Carlos Jaimes-Correa, Francisco Muñoz-Arriola, Shannon Bartelt-Hunt

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Changing water supplies and demands, inherent to climate fluctuations and human activities, are pushing for a paradigm shift in water management worldwide. The occurrence of extreme hydrometeorological and climate events such as extended wet periods and droughts, compounded with contaminants, impair the access to water resources, demanding novel designs, construction, and management across multiple hydrologic scales and biogeochemical processes. A constraint to studying hydrologic and biogeochemical disturbances and improving best management practices for water quantity and quality at the watershed scale resides in the suitable monitoring, data availability, and the creation of frameworks. We hypothesize that streamflow and contaminants, simulated …