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Articles 15541 - 15570 of 198087

Full-Text Articles in Engineering

Medium-Entropy Engineering Of Magnetism In Layered Antiferromagnet CuXNi2(1-X)CrXP2S6, Dinesh Upreti, Rabindra Basnet, M. M. Sharma, Santosh Karki Chhetri, Gokul Acharya, Md Rafique Un Nabi, Joshua Sakon, Mourad Benamara, Mansour Mortazavi, Jin Hu Dec 2024

Medium-Entropy Engineering Of Magnetism In Layered Antiferromagnet CuXNi2(1-X)CrXP2S6, Dinesh Upreti, Rabindra Basnet, M. M. Sharma, Santosh Karki Chhetri, Gokul Acharya, Md Rafique Un Nabi, Joshua Sakon, Mourad Benamara, Mansour Mortazavi, Jin Hu

Physics Faculty Publications and Presentations

Antiferromagnetic van der Waals-type M2P2X6 compounds provide a versatile material platform for studying 2D magnetism and relevant phenomena. Establishing ferromagnetism in 2D materials is technologically valuable. Though magnetism is generally tunable via a chemical way, it is challenging to induce ferromagnetism with isovalent chalcogen and bimetallic substitutions in M2P2X6. Here, we report co-substitution of Cu1+ and Cr3+ for Ni2+ in Ni2P2S6, creating CuxNi2(1-x)CrxP2S6 medium-entropy alloys spanning a full substitution range ( …


Thermal Conductivity Characterization Of High Oleic Vegetable Oils Based Hybrid Nanofluids Formulated Using Gnp, Tio2, Mos2, Al2o3 Nanoparticles For Mql Machining, Anthony Chukwujekwu Okafor, Tobechukwu Kingsley Abor, Saidanvar Esanjonovich Valiev, Ignatius Echezona Ekengwu, Abiodun Saka, Monday Uchenna Okoronkwo Dec 2024

Thermal Conductivity Characterization Of High Oleic Vegetable Oils Based Hybrid Nanofluids Formulated Using Gnp, Tio2, Mos2, Al2o3 Nanoparticles For Mql Machining, Anthony Chukwujekwu Okafor, Tobechukwu Kingsley Abor, Saidanvar Esanjonovich Valiev, Ignatius Echezona Ekengwu, Abiodun Saka, Monday Uchenna Okoronkwo

Chemical and Biochemical Engineering Faculty Research & Creative Works

This paper presents the results of thermal conductivity characterization of six high oleic soybean oil (HOSO) and four high oleic canola oil (HOCO)-Based hybrid nanofluids formulated with four types of nanoparticles (Graphene nanoplatelet (xGnP), TiO2, MoS2, and Al2O3) at nanoparticles wt.% concentration from 1 % to 7 % in 1 % increment using the two-step method for use in MQL machining of difficult-to-cut metals. Thermal conductivity of the formulated hybrid nanofluids were measured using Thermtest Transient Hot Wire Liquid Thermal Conductivity Meter at temperatures from 25 °C to 75 °C in increment …


Dynamic Key-Based Privacy-Preserving Authentication Scheme For Internet Of Drones, Zain Chaudhary Dec 2024

Dynamic Key-Based Privacy-Preserving Authentication Scheme For Internet Of Drones, Zain Chaudhary

Honors Theses

The Internet of Drones (IoD) proliferation has catalyzed transformative changes across various industries, from agriculture to urban management. However, expanding drone networks also presents significant security challenges concerning secure communication and authentication. This paper introduces a robust privacy-preserving key-based authentication scheme tailored explicitly for the IoD, utilizing a matrix key generated by Hierarchical Message Authentication Codes (HMAC) and the SHA-256 algorithm to address these vulnerabilities. Our system enhances security by ensuring each drone in the network can authenticate securely and reliably with a central unit, preventing unauthorized access and securing communications against common threats like eavesdropping and impersonation attacks. Our …


A Fiber Optics Based Surface Enhanced Raman Spectroscopy Sensor For Chemical And Biological Sensing, Jiayu Liu, Bohong Zhang, Amjed Abdullah, Sura A. Muhsin, Jie Huang, Mahmoud Almasri Dec 2024

A Fiber Optics Based Surface Enhanced Raman Spectroscopy Sensor For Chemical And Biological Sensing, Jiayu Liu, Bohong Zhang, Amjed Abdullah, Sura A. Muhsin, Jie Huang, Mahmoud Almasri

Electrical and Computer Engineering Faculty Research & Creative Works

This paper investigates an innovative surface-enhanced Raman scattering (SERS) sensor developed on a side-polished multimode optical fiber core. The optical fiber was integrated into specifically designed 3-dimensional printed mold, where manual polishing of the fiber took place. Microsphere Photolithography (MPL) techniques was employed to pattern periodic nanoantenna arrays on the polished surface, incorporating multiple disk diameters at a fixed periodicity. Subsequent gold deposition/lift-off were carried out to transfer the pattern from the photoresist to the fiber core, resulting in highly periodic hexagonal closed pack (HCP) arrays of nano disks. These arrays can significantly enhance the SERS signal intensity compared to …


Reference Dependence In Queue Design And Pricing Strategies, Jian Liu, Yongpin Zhou, Jian Chen, Peng Li Dec 2024

Reference Dependence In Queue Design And Pricing Strategies, Jian Liu, Yongpin Zhou, Jian Chen, Peng Li

Electrical and Computer Engineering Faculty Research & Creative Works

This research investigates the effect of reference dependence on waiting times in service systems which formerly used a first-in-first-out (FIFO) service but have introduced a priority line with a fee. Our model combines reference-dependent gain-loss utility with standard customer utility, and we posit that customers are pleased with shorter-than-expected waiting times, whereas longer-than-expected times lead to dissatisfaction and an increased likelihood of balking. The study explores two scenarios: a captive customer system (CCS) and a noncaptive customer system (NCCS), with a focus on optimal pricing and segmentation strategies for revenue and social welfare maximization. The results reveal that, in a …


Reinforcement Learning-Based Optimal Control Of Uncertain Nonlinear Systems, Miguel Garcia, Wenjie Dong Dec 2024

Reinforcement Learning-Based Optimal Control Of Uncertain Nonlinear Systems, Miguel Garcia, Wenjie Dong

Electrical and Computer Engineering Faculty Publications

This paper considers the optimal control of a second-order nonlinear system with unknown dynamics. A new reinforcement learning based approach is proposed with the aid of direct adaptive control. By the new approach actor-critic reinforcement learning algorithms are proposed with three neural network approximation. Simulation results are presented to show the effectiveness of the proposed algorithms.


Ohmic Contacts For Fabrication Of Sic Cmos Devices, Anthony Di Mauro Dec 2024

Ohmic Contacts For Fabrication Of Sic Cmos Devices, Anthony Di Mauro

Graduate Theses and Dissertations

Today’s world of electronics is dominated by semiconductor devices which utilize silicon as their substrate material. Though, silicon is not ideal for semiconductor devices in high-voltage or high-temperature applications. Additionally, the efficiency of silicon devices becomes drastically reduced in nonideal operating conditions. Therefore, finding alternatives to silicon?based devices has been a topic for decades now. A few great candidates to replace silicon devices for said applications include Silicon Carbide (SiC), Gallium Nitride (GaN), and Aluminum Arsenide (AlAs). SiC has grown its reputation as the best candidate, when compared to other potential alternatives, due to its wide bandgap, high operating frequency, …


Design And Optimization Of Matrix Core Transformer For High Power Bidirectional Isolated Dc/Dc Converter, Zhe Zhao Dec 2024

Design And Optimization Of Matrix Core Transformer For High Power Bidirectional Isolated Dc/Dc Converter, Zhe Zhao

Graduate Theses and Dissertations

Thanks to the advancement of semiconductor technology, the silicon carbide (SiC) devices with high voltage and power capability are developed and widely used in several industry applications, e.g., gird-connected photovoltaic (PV) system, data center power supply, and electrical vehicle (EV) charging station. After the concept of solid-state transformer (SST) was proposed as an important solution to the medium voltage (MV) power conversion systems, this bidirectional isolated DC/DC converter has attracted much attention in academia and industry. One of the main advantages of SST is to improve both the power density and efficiency of the power conversion system by replacing the …


Multimodal Spectroscopy To Study Tumor Microenvironmental Changes In Vivo, April Mordi Dec 2024

Multimodal Spectroscopy To Study Tumor Microenvironmental Changes In Vivo, April Mordi

Graduate Theses and Dissertations

Every year there are millions of new cancer diagnoses and deaths worldwide. While great strides have been made in technologies and drugs for cancer treatment, there is still a need to understand tumor response to therapy as many patients still endure treatment failure after completing their treatment regimen. Current clinical imaging techniques for detecting response to therapy are utilized weeks to months after the course of treatment, and present limitations to measuring response during treatment. Optical spectroscopy techniques can help meet this need to determine the response of tumors to treatment as it allows for near real-time in vivo characterization …


An Automated Design Flow From Synchronous Rtl To Optimized Layout Using Commercial Eda Tools For Multi-Threshold Null Convention Logic Circuits, Cole Harrington Sherrill Dec 2024

An Automated Design Flow From Synchronous Rtl To Optimized Layout Using Commercial Eda Tools For Multi-Threshold Null Convention Logic Circuits, Cole Harrington Sherrill

Graduate Theses and Dissertations

This work presents the first automated design flow from synchronous RTL to highly optimized layout for Multi-Threshold NULL Convention Logic (MTNCL) circuits. The developed synthesis flow overcomes many of the drawbacks of existing attempts and leverages the advanced optimization features provided by modern synthesis tools. The remaining timing race conditions native to the MTNCL architecture have been identified and thoroughly explored. Two sets of novel timing constraints were devised: the first responds to these race conditions, yielding highly reliable MTNCL circuits; the second directly targets the critical paths within MTNCL circuits, allowing the designer to optimize the target circuit for …


Modeling, Synthesis, And Experimental Characterization Of Rhenium Disulfide For Optoelectronic Devices, Solomon Opeyami Ojo Dec 2024

Modeling, Synthesis, And Experimental Characterization Of Rhenium Disulfide For Optoelectronic Devices, Solomon Opeyami Ojo

Graduate Theses and Dissertations

Two-dimensional (2D) transition metal dichalcogenides (TMDs) have garnered considerable interest for their potential in optoelectronics and photonics owing to their remarkable combination of electronic, optical, and mechanical properties. These characteristics distinguish them from other 2D materials, including graphene, making them particularly valuable for next-generation technologies. This dissertation focuses on ReS₂, a 2D TMD with a unique anisotropic 1T distorted crystal structure. The research aims to elucidate its fundamental properties through a combination of theoretical modeling, material synthesis, and experimental characterization techniques, with the goal of optimizing ReS₂ for device applications. A theoretical investigation utilizing Density Functional Theory …


Two-Photon Imaging For Characterizing Tumor Microenvironmental Changes In Non-Small Cell Lung Cancer Associated With Metastatic Recurrence, Paola Monterroso Diaz Dec 2024

Two-Photon Imaging For Characterizing Tumor Microenvironmental Changes In Non-Small Cell Lung Cancer Associated With Metastatic Recurrence, Paola Monterroso Diaz

Graduate Theses and Dissertations

Lung cancer remains the leading cause of cancer deaths, comprising nearly 25% of all cancer deaths (Sung et al., 2021a). The five-year survival rate of patients with non-small cell lung carcinoma (NSCLC) remains significantly low given that over half present with locally advanced or metastatic disease at time of diagnosis, and experience tumor recurrence following therapeutic intervention (Tamura et al., 2015; Uramoto & Tanaka, 2014). Current evaluation techniques to assess treatment response are lacking, given they are implemented several weeks after treatment completion and are solely based on anatomical changes in tumor size, forgoing other criteria such as functional or …


Causal Discovery In Time Series Data Using Deep Learning Techniques, Saima Zahin Farhana Absar Dec 2024

Causal Discovery In Time Series Data Using Deep Learning Techniques, Saima Zahin Farhana Absar

Graduate Theses and Dissertations

Causal structure learning from observational data has been an active field of research over the past decades. In the literature, different algorithms and models have been proposed, such as constrained-based methods and score-based methods including the emerging deep learning-based methods. However, most of the approaches apply to static and non-dynamic data only. In many applications, the data is temporal. For example, monitoring systems, weather surveillance systems, and stock data, to name but a few. Incorporating temporal information is an important extension of the causal discovery field. With the growth of observational data these days, the discovery of causal relationships from …


Investigation Of Conductive Die-Top Thermal Capacitors During Short Circuit Operation Of Silicon Carbide Devices, Youssef Abotaleb Dec 2024

Investigation Of Conductive Die-Top Thermal Capacitors During Short Circuit Operation Of Silicon Carbide Devices, Youssef Abotaleb

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

Silicon carbide (SiC) power devices have garnered significant attention in recent years due to their superior thermal and electrical properties compared to traditional silicon devices. However, SiC power devices suffer from severe reliability issues arising from their mechanical properties. This is because the Young's modulus of SiC is about three times larger than that of silicon, which correspondingly raises the mechanical stresses acting on the bonding structure, often leading to device failure under power shock events.

Traditional packaging materials and designs tend to constrain SiC performance, as hot-spot temperature resulting from a power shock is one of the key factors …


Identifying Challenges Faced By Small And Medium Enterprises (Smes) In The Middle East And North Africa (Mena) Region Through Total Quality Management, Mohamad Atef Dec 2024

Identifying Challenges Faced By Small And Medium Enterprises (Smes) In The Middle East And North Africa (Mena) Region Through Total Quality Management, Mohamad Atef

Theses and Dissertations

Recently, Small and Medium Enterprises (SMEs) have become recognized as an important driver of global economic growth and innovation. This phenomenon is particularly evident in the MENA region, where small and medium-sized enterprises (SMEs) make a significant contribution to the businesses. SMEs offer significant benefits in terms of job creation, revenue generation, and fostering economic diversity. Although SMEs have a vital contribution in the economy of the MENA region, SMEs face many challenges that hinder their development and long-term viability. Focusing on these challenges is very important for fostering a vibrant and resilient economic environment. The objective of this thesis …


Learning To Represent Temporal Dynamics And Generative Factors For Intelligent Visual Navigation, Sahand Khoshdel Dec 2024

Learning To Represent Temporal Dynamics And Generative Factors For Intelligent Visual Navigation, Sahand Khoshdel

All Theses

Visual navigation systems are crucial in various applications, including autonomous driving, unmanned aerial systems (UAS), and industrial automation. For these systems to operate efficiently in dynamic environments, they must not only interpret complex surroundings but also anticipate changes over time. Temporal prediction—forecasting environmental changes like moving obstacles or shifting lighting conditions—enables navigation systems to act proactively, enhancing both safety and performance. This dissertation investigates representation learning methods both as a backbone feature extractor for RL agents as well as a proxy for systems oriented for Explainable AI (XAI). Two main projects are presented as case studies to achieve the aforementioned …


Using Nano-Ities For Detection Of Metal Ions In Complex Aqueous Solutions, Mohammed Muzammil Nishar Ahmed Dec 2024

Using Nano-Ities For Detection Of Metal Ions In Complex Aqueous Solutions, Mohammed Muzammil Nishar Ahmed

Theses and Dissertations

Recent urbanization has induced a rapid increase in heavy metal exposure to humans. The exploitation of heavy metals for economic gains coupled with poor and economically infeasible recycling methods have led to poor management of heavy metal wastes, which has opened up several pathways for heavy metals to enter the human body. Such heavy metals target many vital organs, but the early symptoms are common and difficult to diagnose. Severe symptoms appear in later stages and are very expensive to treat and the damage caused to the health are not typically reversable in such later stages. To counter this issue, …


Learning-Based Feature Identification For Rendezvous And Capture Of Non-Cooperative Space Objects, Trupti Mahendrakar Dec 2024

Learning-Based Feature Identification For Rendezvous And Capture Of Non-Cooperative Space Objects, Trupti Mahendrakar

Theses and Dissertations

In recent years, On-Orbit Servicing (OOS) and Active Debris Removal (ADR) have attracted increasing interest due to growing concerns about space debris. This debris poses a significant risk to spacecraft, as collisions can catastrophically end missions and potentially trigger a cascading chain reaction of more debris. Space debris ranges from tiny paint chips to large non-functional spacecraft and even launch vehicle components. One way to mitigate the formation of additional space debris is to reduce the total number of large non-cooperative resident space objects present in operational orbits. This can be achieved through two approaches: de-orbiting these objects as part …


Advancing Grid Modernization Through Data-Driven Resilience Modeling And Hosting Capacity Of Distributed Energy Resources, Oscar Samuel Acosta Dec 2024

Advancing Grid Modernization Through Data-Driven Resilience Modeling And Hosting Capacity Of Distributed Energy Resources, Oscar Samuel Acosta

Open Access Theses & Dissertations

This Ph.D. dissertation focuses on advancing the integration of distributed energy resources (DERs) through concepts surrounding their impacts on power system stability, resilience, and hosting capacity (HC). This dissertation addresses crucial topics in renewable energy deployment, transient fault response, and dynamic modeling. The work begins with the development of renewable energy source (RES) models tailored for offsetting residential heating, ventilation, and air conditioning~(HVAC) and commercial cooling loads. These models utilize solar photovoltaic (PV) and wind energy systems to produce scalable frameworks adapted across diverse climates and building types in application of a partial-load targeting methodology. The dissertation then transitions from …


Myofibroblast Targeted Liposomes For The Treatment Of Skin Fibrosis, Elfa Beaven Dec 2024

Myofibroblast Targeted Liposomes For The Treatment Of Skin Fibrosis, Elfa Beaven

Open Access Theses & Dissertations

Continuous overactivation of myofibroblasts leads to excessive deposition of profibrotic proteins, which in turn causes tissue stiffness and, ultimately, organ failure. One of those proteins, Cadherin-11 (CDH11), is reported to be overexpressed in the tissue of fibrotic skin, specifically on myofibroblasts. Similarly, chronic inflammation drives fibrosis progression in autoimmune-related illnesses like systemic sclerosis (SSc). Therefore, it is hypothesized that CDH11 could be a target for cell-specific delivery of antifibrotic therapies to fibrotic skin tissue. Here, a CDH11 peptide conjugated liposome loaded with Tofacitinib, a JAK inhibitor, was developed to understand the potential of targeted therapies to treat skin fibrosis. The …


Developing A Bioengineered Nanoparticle For Improving Oral Absorption Of Iron Supplements., Mila Biswas Dec 2024

Developing A Bioengineered Nanoparticle For Improving Oral Absorption Of Iron Supplements., Mila Biswas

Open Access Theses & Dissertations

Iron deficiency (ID) and iron deficiency anemia (IDA) are widespread nutritional issues, affecting millions globally. Conventional iron supplements often suffer from low absorption rates and gastrointestinal side effects. We investigated β-glucan derivatives as potential carriers to enhance iron absorption and mitigate these drawbacks. This study explored a novel β-glucan-based carrier system loaded with ferrous sulfate heptahydrate. In-vitro studies demonstrated sustained iron stability for over six hours in simulated gastric fluids due to the carrier's affinity for stomach mucin. Particle size analysis and scanning electron microscopy (SEM) images confirmed this specific binding. Additionally, drug release studies revealed a pH-dependent release profile, …


Dynamic Optimization Of Directed Energy Deposition Build Conditions Using Real-Time Monitoring Via Closed-Loop Control, Callan Herberger Dec 2024

Dynamic Optimization Of Directed Energy Deposition Build Conditions Using Real-Time Monitoring Via Closed-Loop Control, Callan Herberger

Open Access Theses & Dissertations

Directed Energy Deposition (DED) is an additive manufacturing process that is being rapidly adopted by industry and is well suited for the fabrication of complex components in various metal alloys. DED provides unique benefits such as design flexibility, the potential for in-situ alloying, and an open environment that allows for unobstructed monitoring within the build chamber. Despite these benefits, fully exploiting additive manufacturing's (AM) potential remains a complex task for designers. This dissertation presents a framework for controlling Directed Energy Deposition process variables through in-situ monitoring. An exploration into modifying AM build conditions through the development and implementation of a …


Uncovering The Light Network Load Performance Penalty Of The Network Link Outlier Factor (Nlof), Michelle Lara Dec 2024

Uncovering The Light Network Load Performance Penalty Of The Network Link Outlier Factor (Nlof), Michelle Lara

Open Access Theses & Dissertations

This thesis evaluates the effectiveness of the Network Link Outlier Factor with Most Likely Link (NLOF: MLL) algorithm under varying network load conditions. Repeated simulation experiments using Mininet were conducted for four different network-wide load levels: 100 Mbps, 500 Mbps, 1 Gbps, and 5 Gbps. Using statistical inference, our experimental results indicate that NLOF: MLL is ineffective under light load conditions (i.e., 100Mbps load) due to the limited network flow data available for its learning process. This limitation highlights a key challenge in applying the algorithm to lightly loaded networks. A preliminary algorithm was proposed to address this light-load performance …


Fatigue Endurance Of Alsi10mg Post Hip Heat Treatment With High Duration Thermal Aging, William Venable Newcomb Dec 2024

Fatigue Endurance Of Alsi10mg Post Hip Heat Treatment With High Duration Thermal Aging, William Venable Newcomb

Open Access Theses & Dissertations

AlSi10Mg is one of the cornerstones of additive manufacturing (AM), with its materialproperties and relatively low cost making it extremely popular as an AM metal choice, specifically using Laser Powder Bed Fusion (LPBF). Many publications have focused on this material, studying tensile strength, fatigue, heat treatments, and more. However, an area that requires further study is the effect of aging on the materials fatigue properties, with this study examining an industry standard heat treatment of Hot Isostatic Pressing (HIP). Using studies that have already been completed, AlSi10Mg was fatigue tested at near 100% UTS and 75% yield strength after HIP …


Monitoring Of Laser Soldering Process In Hybrid Additive Manufacturing, Alexander P. Pustinger Dec 2024

Monitoring Of Laser Soldering Process In Hybrid Additive Manufacturing, Alexander P. Pustinger

Open Access Theses & Dissertations

Additive manufacturing (AM) has been a maturing technology that has expanded over the course of the last decade in major advancements especially in accessibility, process monitoring, modeling, and stock material design. As its industry use is growing, the demand for added improvements such as multi-functionality increases, such as with a hybrid system that allows for modification of printed parts with different electrical components like the Foundry Multi-3D system. The system's purpose is to create AM parts with multifunctional electrical components with the vision to expand to other areas of interest in manufacturing such as ISAM. This work explores the use …


Computational Investigation Of Boundary-Layer Transition Mechanisms In A Blunt Cone, Arturo Rodriguez Dec 2024

Computational Investigation Of Boundary-Layer Transition Mechanisms In A Blunt Cone, Arturo Rodriguez

Open Access Theses & Dissertations

In this study, we have performed two-dimensional steady-state hypersonic CFD and one-and-two-dimensional steady-state heat conduction numerical simulations. We are using them to guide and study hypersonic boundary-layer transition ground testing physical experiments to be performed at Holloman High-Speed Test Track. We use surface heat transfer and fluid flow spot signatures to identify fluid flow regimes using laminar and turbulent numerical simulation solvers to understand boundary-layer transition thermocouple temperatures and fluid flow-forming structures. We have also analyzed the fluid flow in the geometries to be inviscid. We passed the CFD solution into the boundary-layer Harris code developed by NASA to explore …


Intrinsic, Doped And Alloyed Gallium Oxide Films For Optoelectronics, Francelia Sanchez Escobar Dec 2024

Intrinsic, Doped And Alloyed Gallium Oxide Films For Optoelectronics, Francelia Sanchez Escobar

Open Access Theses & Dissertations

Due to the impressive advancement of present technology and increasing energy consumption, there is increasing demand for energy-efficient multifunctional devices based on low-cost, eco-friendly material systems. Gallium oxide (Ga2O3) is an emerging semiconductor with potential for the next generation of power electronics and optoelectronic devices due to its ultra-wide bandgap of 4.8 eV and high theoretical breakdown voltage of 8 MV/cm among other intrinsic properties. Some of the possible applications of β-Ga2O3 include ultra-violet (UV) solar blind photodetectors, field effect transistors, solar cells, and chemical sensors. However, to utilize its full potential, understanding the mechanistic aspects of thin film growth …


Enhanced Redox Storage And Diverse Intercalation In Layered Metal Organic Frameworks With A Staggered Stacking Mode, Satya Prakash Suman Dec 2024

Enhanced Redox Storage And Diverse Intercalation In Layered Metal Organic Frameworks With A Staggered Stacking Mode, Satya Prakash Suman

Open Access Theses & Dissertations

Two-dimensional metal organic frameworks (2D MOFs) with honeycomb-like porous sheets are of growing interest for applications in electrochemical energy storage and electrocatalysis. Notably, 2D MOFs that host their porous sheets in eclipsed or slipped-parallel stacking modes possess continuous one-dimensional pores (1D) and have been widely studied. In contrast, related 2D MOFs with a staggered stacking mode have reduced porosity, are relatively rare, and are largely unexplored for applications. Here we report 2-fold enhanced redox storage and intercalation of diverse ions in a staggered-stacked, nonporous 2D MOF over its eclipsed-stacked, porous counterpart. Interestingly, both MOFs, despite undergoing similar ligand-centered redox processes, …


Demonstrating Feasibility Of Ultrasound-Sensitive Microbubbles Delivery To Treat Disruptions In The Blood Brain Barrier Endothelium, Rubens Jourdain Dec 2024

Demonstrating Feasibility Of Ultrasound-Sensitive Microbubbles Delivery To Treat Disruptions In The Blood Brain Barrier Endothelium, Rubens Jourdain

Theses and Dissertations

Vascular cognitive impairment and dementia (VCID) is one of the main causes of dementia. VCID is caused by age and other genetic factors that lead to disruptions in the blood brain barrier (BBB) and allow blood components to enter the brain. The currently available treatments of VCID include opening the BBB with high-frequency-ultrasound to deliver drugs to the brain. However, this only treats the already developed disease. Consequently, we developed a new drug delivery system whose goal is to restore the brain capillary endothelial cells (BCEC) lining the blood vessel. The objective of this study was to demonstrate the feasibility …


Adsorption Of Harmful Algal Bloom Toxins Using Biochar, Cadianne Chambers Dec 2024

Adsorption Of Harmful Algal Bloom Toxins Using Biochar, Cadianne Chambers

Theses and Dissertations

Harmful Algal Bloom (HAB) events involve the proliferation of microalgae which discharge lethal toxins into fresh and brackish water bodies due to anthropogenic and climatic activities. Common examples of HABs include causative organisms such as Cyanobacteria, Pyrodinium bahamense and more. These genera are known to release potent toxins including Microcystins, and Saxitoxins, respectively, which can seriously endanger human and marine health. Ingestion of these toxins can result in several health problems, such as nausea, vomiting, gastroenteritis, skin irritation, liver damage, paralysis, and respiratory arrest. The Great Lakes, Gulf of Maine, Florida’s coasts, Lake Erie, and Lake Okeechobee have all been …