Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Physical Sciences and Mathematics (40817)
- Civil and Environmental Engineering (39619)
- Electrical and Computer Engineering (36728)
- Mechanical Engineering (29989)
- Computer Engineering (25609)
-
- Computer Sciences (17302)
- Materials Science and Engineering (16404)
- Chemical Engineering (14056)
- Operations Research, Systems Engineering and Industrial Engineering (13789)
- Civil Engineering (11775)
- Biomedical Engineering and Bioengineering (11433)
- Aerospace Engineering (11104)
- Education (8111)
- Social and Behavioral Sciences (7979)
- Environmental Sciences (6929)
- Life Sciences (6292)
- Arts and Humanities (6238)
- Environmental Engineering (6109)
- Transportation Engineering (5909)
- Electrical and Electronics (5692)
- Energy Systems (5619)
- Engineering Science and Materials (5456)
- Artificial Intelligence and Robotics (5388)
- Other Mechanical Engineering (5086)
- Medicine and Health Sciences (4723)
- Geotechnical Engineering (4581)
- Mining Engineering (4553)
- Construction Engineering and Management (4357)
- Business (4257)
- Institution
-
- Missouri University of Science and Technology (21752)
- University of Nebraska - Lincoln (11222)
- California Polytechnic State University, San Luis Obispo (7966)
- University of Kentucky (6342)
- Purdue University (6326)
-
- Air Force Institute of Technology (5697)
- Utah State University (5439)
- Brigham Young University (4850)
- Old Dominion University (4692)
- Technological University Dublin (4606)
- University of Central Florida (4566)
- New Jersey Institute of Technology (4264)
- China Simulation Federation (3880)
- Wright State University (3445)
- Chulalongkorn University (3392)
- Embry-Riddle Aeronautical University (3295)
- University of Texas at Arlington (3180)
- TÜBİTAK (3106)
- Engineering Conferences International (2957)
- University of Arkansas, Fayetteville (2826)
- Louisiana State University (2820)
- Portland State University (2757)
- Michigan Technological University (2628)
- Clemson University (2498)
- University of South Carolina (2359)
- University of Texas at El Paso (2141)
- Marquette University (2082)
- Chinese Chemical Society | Xiamen University (2026)
- Washington University in St. Louis (1825)
- China Coal Technology and Engineering Group (CCTEG) (1799)
- Keyword
-
- Engineering (2858)
- Machine learning (1429)
- Optimization (1215)
- Simulation (1169)
- Applied sciences (1099)
-
- Construction (892)
- Design (871)
- Sustainability (859)
- Machine Learning (828)
- Deep learning (806)
- Modeling (741)
- Additive manufacturing (576)
- Concrete (543)
- Safety (532)
- Computer Science (525)
- Architecture (524)
- Artificial intelligence (501)
- Building (498)
- Nanoparticles (476)
- Robotics (474)
- Education (462)
- CFD (448)
- UAV (441)
- Corrosion (440)
- Energy (440)
- Engineering education (424)
- Conference (411)
- ASME (401)
- Proceedings (401)
- Mechanical Engineering (389)
- Publication Year
-
- 2026 (5111)
- 2025 (8574)
- 2024 (9139)
- 2023 (9704)
- 2022 (9297)
-
- 2021 (9963)
- 2020 (10629)
- 2019 (10492)
- 2018 (8945)
- 2017 (8343)
- 2016 (9589)
- 2015 (7510)
- 2014 (7238)
- 2013 (7289)
- 2012 (6302)
- 2011 (5801)
- 2010 (5369)
- 2009 (4157)
- 2008 (4190)
- 2007 (3831)
- 2006 (3391)
- 2005 (3074)
- 2004 (2785)
- 2003 (2071)
- 2002 (1792)
- 2001 (1795)
- 1999 (1307)
- 1998 (1354)
- 1993 (1343)
- 1991 (1363)
- Publication
-
- Theses and Dissertations (11490)
- Electronic Theses and Dissertations (4180)
- Masters Theses (3914)
- Journal of System Simulation (3880)
- Electrical and Computer Engineering Faculty Research & Creative Works (3516)
-
- Theses (3460)
- Nebraska Tractor Tests (3397)
- Faculty Publications (3292)
- Turkish Journal of Electrical Engineering and Computer Sciences (3106)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (2554)
- International Conference on Case Histories in Geotechnical Engineering (2055)
- Master's Theses (2027)
- Journal of Electrochemistry (2026)
- Dissertations (1866)
- Kentucky Transportation Center Research Report (1816)
- Doctoral Dissertations (1800)
- Coal Geology & Exploration (1799)
- International Conferences on Recent Advances in Geotechnical Earthquake Engineering and Soil Dynamics (1566)
- USF Tampa Graduate Theses and Dissertations (1463)
- Articles (1409)
- Browse all Theses and Dissertations (1369)
- Computer Science & Engineering Syllabi (1312)
- LSU Master's Theses (1307)
- Journal of Marine Science and Technology–Taiwan (1299)
- Open Access Theses & Dissertations (1295)
- Mechanical and Aerospace Engineering Faculty Research & Creative Works (1284)
- Civil, Architectural and Environmental Engineering Faculty Research & Creative Works (1264)
- Publications (1245)
- All Theses (1237)
- Graduate Theses and Dissertations (1219)
- Publication Type
Articles 12961 - 12990 of 195926
Full-Text Articles in Engineering
Enhanced Diagnostics And Surveillance Of Enteroviruses Including Serotypes Associated With Acute Flaccid Myelitis, Denise Lynette Kramer
Enhanced Diagnostics And Surveillance Of Enteroviruses Including Serotypes Associated With Acute Flaccid Myelitis, Denise Lynette Kramer
Browse all Theses and Dissertations
Prior to 2014, Enterovirus D68 infections typically caused symptoms resembling the common cold. From 2014-2018, D68 was associated with an increase in acute flaccid myelitis. However, since 2020, neurological complications have all but disappeared. We selected 1076 respiratory specimens previously determined to be positive for rhinovirus or enterovirus from Department of Defense members and their beneficiaries collected globally from October 2018 through January 2024 and underwent sequencing. Of these specimens, 93.7% were identified as rhinoviruses, while 6.3% were enteroviruses, including 30 enterovirus D68. We utilized the Nextstrain bioinformatic pipeline to reconstruct the phylogenetic relationship of these 30 D68 viruses. Twenty-two …
Leveraging Counterfactuals For Enhanced Natural Language Inference: A Multitask Knowledge Distillation Approach, Brian J. Davis
Leveraging Counterfactuals For Enhanced Natural Language Inference: A Multitask Knowledge Distillation Approach, Brian J. Davis
Browse all Theses and Dissertations
Natural-language inference (NLI) asks whether a hypothesis is entailed by, contradicts, or is neutral with respect to a premise. Modern transformers reach high raw accuracy on benchmarks such as SNLI, MNLI, and ANLI, yet they often rely on brittle lexical shortcuts and provide little insight into their decision process. This thesis shows that counterfactual-augmented knowledge distillation can simultaneously boost robustness and supply faithful, token-level explanations—without scaling model size. Four T5-v1_1 students (60M, 220M, 770M, 3B parameters) are trained under four curricula: (1) standard fine-tuning, (2) fine-tuning with free-text rationales, (3) multi-task distillation with naive counterfactuals, and (4) multi-task distillation with …
Hardware Trojan Detection In A Segmented Mixed-Signal Circuit Via Leakage Current, Christopher James Otey
Hardware Trojan Detection In A Segmented Mixed-Signal Circuit Via Leakage Current, Christopher James Otey
Browse all Theses and Dissertations
As computers and integrated circuits become more commonplace, the risk of a Hardware Trojan attack becomes more worrisome. Trojans can exploit design flaws or be inserted between essential components to leak information, change the circuit function, or destroy the circuit altogether. Several methods of trojan detection and prevention have been introduced, however few can handle combined analog and digital circuits, known as mixed-signal circuits. This thesis demonstrates a Hardware Trojan detection method implemented in an Analog-to-Digital Converter (ADC), which is a mixed-signal circuit. The detection method involves splitting the circuit into segments with approximately equal leakage currents (a large part …
Computational Analysis Of A Hafnium-Titanium Alloy Mechanical Properties From First Principles, Abdul Mughni
Computational Analysis Of A Hafnium-Titanium Alloy Mechanical Properties From First Principles, Abdul Mughni
Browse all Theses and Dissertations
Hafnium and titanium, along with zirconium, are refractory metals with unique properties suitable for extreme-environment applications. Utilizing alloys based on these elements can provide suitable materials with engineered properties. Understanding their mechanical properties is necessary to determine appropriate applications. This thesis research aims at employing quantum-based atomistic simulations to estimate mechanical properties of pristine hafnium, titanium and an alloy based on these elements. The results are compared to available experimental data and the corresponding implications are explored.
Data-Driven Prediction Of Temperature Distribution In Multi-Laser Powder Bed Fusion Using Convolutional Neural Networks, Majid Dousti
Data-Driven Prediction Of Temperature Distribution In Multi-Laser Powder Bed Fusion Using Convolutional Neural Networks, Majid Dousti
Browse all Theses and Dissertations
Additive Manufacturing (AM), particularly Laser Powder Bed Fusion (L-PBF), has gained significant traction in fabricating complex, high-performance metallic components. However, the inherent complexity and computational cost of high-fidelity simulations pose challenges for real-time monitoring and optimization of multi-laser powder bed fusion processes. This study proposes a data-driven surrogate modeling approach using a deep learning architecture to efficiently and accurately predict three-dimensional temperature distributions during ML-PBF. A 3D convolutional neural network (CNN) model, named Decoder-CNN, is developed and trained on a dataset of simulated thermal fields corresponding to various process configurations, including different laser power, scanning speed, and beam arrangements. The …
Optimizing Cloud Computing Resources For Operational Cost And Application Performance Using Machine Learning, Isaac K. Matthew
Optimizing Cloud Computing Resources For Operational Cost And Application Performance Using Machine Learning, Isaac K. Matthew
Browse all Theses and Dissertations
As AI-driven workloads accelerate the growth of cloud initiatives and spending, resource waste also increases due to persistent inefficiencies in cloud compute and infrastructure management. Overprovisioned resources and suboptimal configurations often lead to operational inefficiencies and unnecessary financial overhead. These challenges arise from the difficulty of anticipating resource demands in dynamic workloads and selecting suitable virtual machines to ensure optimal performance. Our research proposes a holistic, data-driven framework for managing cloud compute resources that reduces costs without compromising application performance. We integrate a predictive, model-driven, threshold-based autoscaling solution for cloud-native applications with an optimized instance right-sizing approach to select cost-effective …
Evaluating Geometric Accuracy In 3d Printing (3dp) Comparative Study Of Different 3dp Processes Using Cmm And Vision Measurement Tools, Alexander Adams
Evaluating Geometric Accuracy In 3d Printing (3dp) Comparative Study Of Different 3dp Processes Using Cmm And Vision Measurement Tools, Alexander Adams
Browse all Theses and Dissertations
This study investigates how various additive manufacturing (AM) technologies and parameters influence part quality by fabricating three uniquely designed artefacts. Artefact 1 is a rectangular block with stepped arches, thin and solid extruded features, and holes of varying shapes and sizes. Artefact 2 consists of a base plate with angled overhangs from 15 to 90 degrees. Artefact 3 includes a tall cylinder, a five-step cylinder, and two half arches of different scales. Each artefact was printed ten times using: metal PBF (Inconel 718), nylon PBF (Nylon 12), Vat Polymerization (GRY photopolymer), and material extrusion (nylon carbon fiber). Dimensional analysis was …
Reducing Operator Training Time Through Virtual Reality: A Case Study On The Lpkf Protomat E44 Machine, Joshua C. Patel
Reducing Operator Training Time Through Virtual Reality: A Case Study On The Lpkf Protomat E44 Machine, Joshua C. Patel
Browse all Theses and Dissertations
This thesis presents the development of an immersive virtual reality (VR) simulation that replicates the operation of the LPKF ProtoMat E44 PCB milling machine. Aimed at reducing operator training time and improving procedural understanding, the simulation offers an interactive and realistic environment where users can safely engage with machine workflows and start-up sequences. The emphasis is on accurate representation, usability, and maintaining immersion to support intuitive learning. Although formal evaluation is outside the scope of this work, the system is designed to serve as a foundation for cost-effective, scalable training in technical and manufacturing contexts, offering a modern alternative to …
Study Of Fiber-Loaded Slurries For Ceramic Matrix Composite Fabrication By Additive Manufacturing, Gaspard Matondo
Study Of Fiber-Loaded Slurries For Ceramic Matrix Composite Fabrication By Additive Manufacturing, Gaspard Matondo
Browse all Theses and Dissertations
We studied the additive manufacturing of an alumina-matrix composite reinforced with alumina fibers using the Admatec Admaflex 3D printer, which utilizes digital light processing technology. Oxide-oxide composites are composite materials in which both the matrix and the reinforcing element are ceramic oxides. Monolithic alumina ceramic exhibits a good combination of thermal and mechanical properties, including thermal shock resistance, high melting point, thermal oxidation resistance, good thermal conductivity, hardness, and mechanical strength. However, it is very brittle. Introducing alumina fiber as a reinforcing material into the alumina matrix is expected to enhance mechanical properties, particularly toughness, making the ceramic matrix composite …
Reinforcement Learning For Adversarial Systems Using Relational Observations, Sophia Christine Gilson
Reinforcement Learning For Adversarial Systems Using Relational Observations, Sophia Christine Gilson
Browse all Theses and Dissertations
This thesis investigates the integration of relational observations with the reinforcement learning (RL) framework for improved generalization capability. A hide-and-seek simulation environment is designed in Unity for proof-of-concept demonstration. Two observation representations—relational (analogical) and standard positional—are designed to evaluate agent learning and generalization capabilities. Agents are trained using the Proximal Policy Optimization (PPO) and Soft Actor Critic (SAC) algorithms in a random-room environment and tested in both the random-room environment and a novel environment with greater spatial complexity and path obstructions. Comparative studies indicate that relational representation of objects in the adversarial environment could potentially improve the generalization capability of …
Scalable Real-Time Stream Clustering For Unbounded Text Streams, Nathaniel C. Crossman
Scalable Real-Time Stream Clustering For Unbounded Text Streams, Nathaniel C. Crossman
Browse all Theses and Dissertations
Social media, AI systems, IoT sensors, and other platforms generate vast amounts of streaming data. Given this vast volume of information, techniques that can reduce and aggregate data into meaningful topics are essential. One such technique is the two-phase stream clustering approach. In the first, online micro-clustering phase, the system forms micro-clusters from the incoming data stream, incrementally merges new items into related existing micro-clusters, and prunes or fades micro-clusters as they become inactive, producing a constantly updating yet compact set of micro-clusters representing potential topics and subtopics of the stream. In the second, offline macro-clustering phase, these micro-clusters are …
Patient Subset Classification Using Encoded Embeddings And Knowledge Graph Retrieval-Augmented Generation, Benjamin A. Holmes
Patient Subset Classification Using Encoded Embeddings And Knowledge Graph Retrieval-Augmented Generation, Benjamin A. Holmes
Browse all Theses and Dissertations
The widespread adoption of electronic medical records has created a vast reservoir of clinical data that can be leveraged to better understand how interventions relate to patient outcomes. Much of this information, however, exists as unstructured free-text, posing significant challenges for traditional statistical and machine-learning methods. Solving these challenges would allow the extraction of specific patient subpopulations (clinically relevant cohorts of individuals who share overlapping symptoms, risk factors, or diagnostic criteria), which could be used in precision medicine. Despite this promise, extracting these subpopulations from unstructured medical notes is an ongoing challenge due to the variability of clinical language and …
Using Unsupervised Machine Learning To Experimentally Categorize Separation On Low-Pressure Turbine Blades, Aaron B. Suter
Using Unsupervised Machine Learning To Experimentally Categorize Separation On Low-Pressure Turbine Blades, Aaron B. Suter
Browse all Theses and Dissertations
Laminar boundary layer separation can significantly degrade the efficiency of Low-Pressure Turbine (LPT) blades. While active flow control (AFC) methods can mitigate these losses, energy-efficient implementation requires activating the system only when performance decreases. This study validates an unsupervised machine learning framework that utilizes sparse, discrete surface-pressure measurements to distinguish between high and low aerodynamic loss states. A fuzzy c-means (FCM) clustering model was trained on limited pressure data obtained in a low-speed linear cascade across Reynolds numbers from 30,000 to 160,000 and used to categorize the flow regime in real time. At Re = 40,000, vortex generator jet (VGJ) …
Vagus Nerve Stimulation Ameliorates Cognitive Impairment Caused By Hypoxia, Birendra Sharma
Vagus Nerve Stimulation Ameliorates Cognitive Impairment Caused By Hypoxia, Birendra Sharma
Browse all Theses and Dissertations
Hypoxia disrupts brain function due to the high demand for oxygen, leading to significant cognitive impairments. While vagus nerve stimulation (VNS) has been shown to enhance cognition, its ability to counteract hypoxia-induced deficits remains unclear. In this study, male Sprague–Dawley rats were assigned to sham, hypoxia, or VNS + hypoxia groups, with VNS delivered during hypoxia (8% oxygen) using biphasic pulses (100 μs, 30 Hz, 0.8 mA). Cognitive performance was evaluated using multiple behavioral paradigms, and hippocampal tissue was analyzed for neurotrophin expression through quantitative PCR and immunohistochemistry. Among the behavioral measures, hypoxia specifically impaired performance on the passive avoidance …
Utilizing Optimization Tools For Passive Flow Control Passage Loss Reduction In Low-Pressure Turbines, Bryant Robert Duane Burton
Utilizing Optimization Tools For Passive Flow Control Passage Loss Reduction In Low-Pressure Turbines, Bryant Robert Duane Burton
Browse all Theses and Dissertations
Low-pressure turbines (LPTs) play a crucial role in fuel efficiency and thrust generation of aero-engines. Traditional LPT designs, however, involve multiple stages and numerous blades, resulting in increased weight and manufacturing costs. The challenge of modern- day researchers is to reduce the weight and cost but maintain the high efficiency of LPTs. To address this, one approach is to increase the aerodynamic loading of individual blades, reducing the blade count. However, this can lead to increased secondary losses caused by flow separation, particularly in the endwall regions. This research focuses on optimizing the blade profile at the junction with the …
Quantification Of Porosity In Hfb2–20%Sic Using Convolutional Neural Networks, Cameron J. Floyd
Quantification Of Porosity In Hfb2–20%Sic Using Convolutional Neural Networks, Cameron J. Floyd
Browse all Theses and Dissertations
Ultra-high-temperature ceramics, commonly used in aerospace applications, operate in high-temperature oxidizing environments where a surface scale forms and regulates oxy gen access. For hafnium diboride–silicon carbide (HfB2–SiC), that scale consists of a borosilicate glass layer over a porous HfO2 skeleton. Oxygen transport through this poros ity governs the kinetics of mechanistic models, requiring reproducible inputs for accurate pore fraction (PF), pore-size distributions, and ultimately tortuosity. This thesis replaces rule-based SEM thresholding with a convolutional neural network that segments pores and predicts the pore-radius distribution for transport models. The resulting calibrated porosity maps and size distributions transfer within the acquisition domain …
Effect Of Build Orientation And Environmental Conditions On Mechanical And Geometric Properties Of Polymeric Parts Fabricated By The Powder Bed Fusion Process, Adedamola O. Adeyemi
Effect Of Build Orientation And Environmental Conditions On Mechanical And Geometric Properties Of Polymeric Parts Fabricated By The Powder Bed Fusion Process, Adedamola O. Adeyemi
Browse all Theses and Dissertations
Polyamide-12 (aka PA12) is a synthetic thermoplastic polymer that has been used in various applications, including the electronic and electrical, oil and gas industrial manufacturing and automotive industry. There are several ways to manufacture parts with PA12 and PA12 based composites. Injection molding, a traditional manufacturing process, has been the standard manufacturing route for polymers for a long time. Recently, however, additive manufacturing (AM) processes, such as powder bed fusion (PBF) and material extrusion (ME) have been introduced. PBF is a manufacturing process characterized by the selective sintering of successive layers of powdered material. It is the most effective AM …
Generative Adversarial Networks (Gans) For High-Dimensional Biological Data, Harigovind Harikumar
Generative Adversarial Networks (Gans) For High-Dimensional Biological Data, Harigovind Harikumar
Browse all Theses and Dissertations
This thesis investigates the application of Generative AI models, mainly Generative Adversarial Network (GAN) models to high dimensional and low sample size biological datasets like Motion Sickness, Breast Cancer, Crohn, and Melanoma. We utilized and compared three generative AI frameworks: Vanilla GAN, Wasserstein GAN (WGAN), Locality-Sensitive Hashing GAN (LSH-GAN) and Omics GAN. To address the challenges associated with high-dimensionality and low sample size, which was leading to very poor outputs of biological synthetic samples, we came up with an approach to stop the model when it reaches its saturation level. That is, we printed the loss plots to see where …
The Role Of Trpm7 In Mouse Development And Immune Cell Function, Jananie Rockwood
The Role Of Trpm7 In Mouse Development And Immune Cell Function, Jananie Rockwood
Browse all Theses and Dissertations
Transient receptor melastatin 7 (TRPM7) functions both as an ion channel and a protein kinase. TRPM7 has been implicated in Mg2+ homeostasis, embryogenesis, cardiac automaticity, and immunity. The purpose of this research was to deepen our understanding of TRPM7 channel and kinase functions. To this end, we used two transgenic mouse models: the TRPM7 gain-of-function (GOF) and TRPM7 kinase-dead (KD) mice to address the consequences of increased channel activity and kinase inactivation, respectively. Global deletion of TRPM7 or the kinase domain alone are embryonic lethal, therefore, we used the TRPM7 GOF mouse to investigate germline transmission. We examined embryo development …
Pixmix Attack: Implementation And Evaluation Of A Novel Pixel Injection On Digital Video Port (Dvp) Interface In Embedded Camera Systems With Pcb Hardware Trojan, Sayed Md Tashfi Nowroz
Pixmix Attack: Implementation And Evaluation Of A Novel Pixel Injection On Digital Video Port (Dvp) Interface In Embedded Camera Systems With Pcb Hardware Trojan, Sayed Md Tashfi Nowroz
Browse all Theses and Dissertations
Image sensors are at the heart of machine vision systems in robotics, industrial automation, and surveillance systems which ideally operate with minimal human supervision and only occasional maintenance. The image sensors convert visible light into electrical signals which are locally decoded to image on the printed circuit board (PCB) by an ordinary embedded processor System on Chip (SoC). This thesis investigates a critical vulnerability in such systems, targeting the communication protocol at the signal level during runtime. Specifically, it focuses on a novel attack in the Digital Video Port (DVP) protocol, possible to exploit with PCB-based hardware Trojans, to craft …
Induced Reduction Of N-Glycosylation Leads To Heart Failure, Anthony M. Young
Induced Reduction Of N-Glycosylation Leads To Heart Failure, Anthony M. Young
Browse all Theses and Dissertations
Cardiovascular disease is the leading cause of death and contributes to the increasing global prevalence of heart failure (HF). N-glycosylation is a common co-/post-translational modification where branching oligosaccharides are bound to the extracellular domain of membrane proteins. This creates a diverse range of glycan structures and requires the coordination of hundreds of regulated genes. Inherited mutations in glycan synthesis frequently present with cardiomyopathies leading to HF with reduced ejection fraction (HFrEF). Additionally, gene expression studies of HFrEF patients have shown altered expression of glycosylation-related genes, including alpha-1,3-mannosyl-glycoproten 2-beta-N acetlyglucosaminyltransferase (Mgat1). This gene encodes N-acetylglucosaminyl transferase 1 (GlcNAcT1) which is required …
A Secure Ml-Assisted Framework For Resilient And Efficient Prediction Of Physiotherapy Sequence In Bilateral Carpal Tunnel Syndrome, Pratik Pandurang Kharat
A Secure Ml-Assisted Framework For Resilient And Efficient Prediction Of Physiotherapy Sequence In Bilateral Carpal Tunnel Syndrome, Pratik Pandurang Kharat
Browse all Theses and Dissertations
Bilateral idiopathic carpal tunnel syndrome (CTS) is a neuromuscular disorder characterized by compression of the median nerve at both wrists, leading to symptoms such as pain, numbness, tingling, and muscle weakness. Unlike unilateral cases, bilateral idiopathic CTS presents distinct therapeutic challenges due to the simultaneous involvement of both hands and the lack of an identifiable underlying cause. This study explores the application of machine learning techniques to predict the optimal sequence of physiotherapeutic interventions Stretching followed by Myofascial Mobilization (S/M) or the reverse (M/S) in female patients with bilateral idiopathic CTS and right hand dominance. Data were drawn from a …
The Impact Of Ahr And Hs1.2 Enhancer Genetic Variations On Igh Expression And Antibody Production In Human B Cells, Mili Santosh Bhakta-Yadav
The Impact Of Ahr And Hs1.2 Enhancer Genetic Variations On Igh Expression And Antibody Production In Human B Cells, Mili Santosh Bhakta-Yadav
Browse all Theses and Dissertations
Antibody production is an essential component of the immune response against pathogens. The immunoglobulin heavy chain (IgH) gene codes for the heavy chain of antibodies. The IgH constant regions Cμ, Cδ, Cγ1-4, Cα1-2, and Cε encode the five major classes of antibodies, i.e., IgM, IgD, IgG1-4, IgA1-2, and IgE, respectively. The transcription of the IgH gene and class switch from IgM to other isotypes is regulated by two 3’ IgH regulatory regions (3’IgHRRs), each of which is a cluster of three enhancer regions (hs3, hs1.2 and hs4). The genetic variations in the hs1.2 enhancer have been identified; a ~53 bp …
Learning Under Data Scarcity: Reasoning And Negative Distillation For Texts And Graphs, Calvin T. Greenewald
Learning Under Data Scarcity: Reasoning And Negative Distillation For Texts And Graphs, Calvin T. Greenewald
Browse all Theses and Dissertations
Modern machine learning (ML) models rely on large amounts of high-quality labeled data to achieve optimal performance. However, in many real-world domains, such as cyber security, acquiring sufficient labeled data is often infeasible due to cost, privacy concerns, and the rapid evolution of underlying phenomena. This challenge underscores the importance of learning under data scarcity. This thesis addresses this challenge by proposing distinct, modality-specific techniques for text and graph domains, which allow models to generalize effectively with minimal data. For text classification task, we incorporate distilled rationales from large language models and adversarial perturbations into the input space to improve …
Actuator Disk Model For Aeropropulsive Coupling Effects In Vortex Particle Method, Eduardo Alvarez, Vineet Ahuja, Vinod Lakshminarayan, Aaron Perry, Ryan Anderson, Andrew Ning
Actuator Disk Model For Aeropropulsive Coupling Effects In Vortex Particle Method, Eduardo Alvarez, Vineet Ahuja, Vinod Lakshminarayan, Aaron Perry, Ryan Anderson, Andrew Ning
Faculty Publications
Blown lift and distributed electric propulsion aircraft pose strong aeropropulsive coupling effects that cannot be ignored during the early stages of design. In this study, we develop an advanced actuator disk model (ADM) for aeropropulsive coupling effects of ducted fans with the vortex particle method (VPM). The advanced ADM consists of (1) an actuator disk at the rotor plane, (2) a surface vortex sheet modeling the mixing and convection of blade tip vorticity along walls, and (3) a powered wake at the exhaust. With these three components, a propulsion jet with an arbitrary velocity profile is formed and interactions with …
Molecular Modeling Methods And Applications For Accelerating Polymerization And Pyrolysis Studies, Joshua D. Kemppainen
Molecular Modeling Methods And Applications For Accelerating Polymerization And Pyrolysis Studies, Joshua D. Kemppainen
Dissertations, Master's Theses and Master's Reports
Polymer matrix composites and carbon-carbon composites play critical roles in the aerospace, automotive, and construction industries. Different matrix materials and processing conditions can lead to a large variety of composite materials and composite properties. Integrated computational materials engineering has been used to tailor PMC matrix materials and processing conditions to specific properties and manufacturing techniques. The integrated computational materials engineering process modeling framework uses molecular dynamics at the nanometer length scale to characterize the evolving thermo-mechanical properties of the polymer as it cures. Then finite element analysis is used at the micrometer length scale to adjust cure cycles to tailor …
Ansi Z97 Impact Testing Of Thin Glass, Justin P. Anthony
Ansi Z97 Impact Testing Of Thin Glass, Justin P. Anthony
Dissertations, Master's Theses and Master's Reports
To determine whether thin glass constructions can pass Z97 impact test to qualify as safety glass an extensive protocol was performed. Constructions including monolithic, chemically strengthened, filmed, laminated, and triple pane insulated glass units comprised of thin glass ranging in thickness between 0.50 mm and 1.6mm were evaluated. Test results indicate annealed specimens, and laminated specimens performed similar to constructions with 3 mm and 6 mm glass. Specimens with 0.2 mm film consistently performed as safety glass for thicknesses between 0.7 mm and 1.6 mm and similar performance for specimens with 0.1 mm film with thickness of 1.1 mm and …
Life Cycle Assessment And Techno-Economic Analysis Of Mine Tailings As A Sustainable Raw Material For Mineral Carbonation And Recovery Of Critical Minerals, Vida Amankwaa
Dissertations, Master's Theses and Master's Reports
This study assesses the feasibility of using mine tailings for mineral carbonation and nickel recovery through a comprehensive Life Cycle Assessment (LCA) and Techno-Economic Analysis (TEA). The LCA quantifies greenhouse gas emissions, energy use, and resource consumption, while the TEA evaluates capital investment, operational costs, and process efficiency. The conventional beneficiation process at Eagle Mine serves as a baseline, highlighting its environmental footprint and operational costs. Results indicate that tailings reprocessing incurs higher costs ($34.76 per tonne of tailings processed) compared to conventional ore processing ($25.90 per tonne) due to increased energy consumption and material handling requirements. Additionally, several mineral …
Life Cycle Assessment Of Renewable Hydrocarbon Fuels Produced By The New Cool Gas To Liquid (Cool Gtl) Process, Elochukwu Okoye
Life Cycle Assessment Of Renewable Hydrocarbon Fuels Produced By The New Cool Gas To Liquid (Cool Gtl) Process, Elochukwu Okoye
Dissertations, Master's Theses and Master's Reports
The Cool Gas-to-Liquid (Cool GTL) process converts biogas and captured CO2 into renewable hydrocarbon fuels, contributing to GHG emissions reduction in transportation. This report explains a Life Cycle Assessment (LCA) study that was completed to evaluate the environmental impact of different feedstocks, hydrogen sources, and electricity inputs. The analysis considers biogas from food waste, manure, and landfill sources, as well as biogenic, fossil, and direct air capture (DAC) CO2 feedstocks. Results show that biogas pathways provide the greatest GHG reductions, with the best case (food and manure biogas + solar hydrogen + solar electricity) achieving a net-negative GWP …
Characterization Of Krypton Performance In A Laboratory 300 W Magnetically Shielded Hall-Effect Thruster, Jacob Henry Knott
Characterization Of Krypton Performance In A Laboratory 300 W Magnetically Shielded Hall-Effect Thruster, Jacob Henry Knott
Dissertations, Master's Theses and Master's Reports
Xenon has long been the propellant of choice in Hall Thrusters; however, significant work has been performed to produce thrusters capable of utilizing alternate propellants due to xenon’s price and scarcity. Krypton is the most similar alternative propellant to xenon. This work examines the performance of a sub-kilowatt magnetically shielded Hall Thruster operating on both xenon and krypton. Krypton produced lower thrust, specific impulse, and was less efficient than xenon. Specifically, the absolute xenon-krypton efficiency gap was 6 to 24 % . Krypton’s inferior efficiency is primarily attributable to differences in mass utilization and beam divergence losses. The impacts of …