Nursing Care For A Patient With Nstemi Admitted To The Coronary Care Unit For Percutaneous Coronary Intervention — A Case Study,
2017
Universiti Brunei Darussalam
Nursing Care For A Patient With Nstemi Admitted To The Coronary Care Unit For Percutaneous Coronary Intervention — A Case Study, Siti Maryati M. S., Dioso R. (Ii) P.
ASEAN Journal on Science and Technology for Development
This case studyaims to demonstrateclinical nursing skills to a patient with myocardial infarction admitted for percutaneous coronary intervention. Nursing care for this patient startedwith a physical assessment and laboratory invesigation analysis. This evaluation was necessary to develop a nursing care plan. The activities in the ward enumerated the medications provided, and the details of the vital signs monitored hourly. The patient was sent to cardiac catheter laboratory at 1030H. From the cardiac catheter laboratory post-percutaneouscoronary intervention to the mid-right coronary artery (1 Drug-Eluting Stent) he was transferred out to Telemetry unit on 11 August2016 at 1500H with Terumo band hemostatic …
Evaluation Of Cooking Oil As Processing Addtive For Natural Rubber,
2017
Universiti Brunei Darussalam
Evaluation Of Cooking Oil As Processing Addtive For Natural Rubber, Syamin Y. M., Azemi S., Dzaraini K.
ASEAN Journal on Science and Technology for Development
It was reported recently that high amount of aromatic ring or number of polycyclic aromatic hydrocarbon compounds found in aromatic oil are carcinogenic. This paper discusses the work to evaluate the Malaysian cooking oil as an alternative option to be used as process oil since cooking oil is safe to use and non-toxic. The performance of cooking oil is compared againstaromatic and paraffinioils. The results showed that rubber compounds containing cooking oil produced almostsimilar cure characteristicsas those produced by aromatic and paraffinioils indicating that it did not interfere with the vulcanization reaction. The physical properties of the vulcanizates containing cooking …
Increasing Serum Cholesterol Level Among Sri Lankan Adult Obese Patients Admitted To Medical Wards: A Cross-Sectional Study,
2017
Universiti Brunei Darussalam
Increasing Serum Cholesterol Level Among Sri Lankan Adult Obese Patients Admitted To Medical Wards: A Cross-Sectional Study, Dioso R. (Ii) P., Shalina K., Judenimal K.
ASEAN Journal on Science and Technology for Development
This research identifid the factors affcting the widespread of the level of serum cholestrol among adult obese patients admitted to government hospitals in the easternpart of Sri Lanka, and identifie the number of adults obese patients with increasing serum cholesterollevel. A descriptive cross-sectional studydesign was used. Convenience sampling technique helped select 150 patients in medical wards and clinics of two government hospitals in the easternprovince of Sri Lanka, and Questionnaireswere distributedfor data analysis. Overall findingsof 150 obese patients regarding increasing serum cholestrol level admitted in the medical wards and follow-up at medical clinics had 59% in moderate risk, 36% with …
Prevalence Of Diarrhoeal Diseases Among Children Under Five Years In East African Countries From 2012–2017,
2017
Universiti Brunei Darussalam
Prevalence Of Diarrhoeal Diseases Among Children Under Five Years In East African Countries From 2012–2017, Elmi O. E., Dioso R. (Ii) P.
ASEAN Journal on Science and Technology for Development
This meta-analysis analyzed the prevalence of diarrheoal diseases among children less than fiveyears in three selected Eas African countries from 2012–2017. Search engines used Google Scholar, Proquest,and PubMed. Primarily, 300 studes were selected; hence 297 were eliminated using inclusion and exclusion criteria. The PICO (population, intervention, comparison, and outcome) guide helped in the analysis of the three selected stdies. The prevalence of diarrhoea among children less than fiveyears in the three selected EastAfrican countries from 2012 to 2017, averaged to 27% range from a minimum of 11% to a maximum of 54% of the 5478 total respondents (OR 2.07). The …
Hydrocarbons As Refrigerants―A Review,
2017
Universiti Brunei Darussalam
Hydrocarbons As Refrigerants―A Review, Koh J. H., Zakaria Z.
ASEAN Journal on Science and Technology for Development
Refrigerants used in air conditioning and refrigeration (AC&R) indusries have come full circle since the beginning of the industrialrevolution. With concern on issues relating to the environment such as the global warming and climate change issues, we should finda better alternative than to continue using these refrigerants that cause global warming and ozone depletion. AC&R industryplayers have blended in by introducing some new equipment and components that are specificallydesigned for hydrocarbon (HC) use. Mostnew refrigerators sold in Malaysia are already equipped with isobutane [a hydrocarbon designated as R-600a by the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE) standards]as …
The Role Of Interactions Of Long Non-Coding Rnas
And Heterogeneous Nuclear Ribonucleoproteins In
Regulating Cellular Functions,
2017
University of Nebraska - Lincoln
The Role Of Interactions Of Long Non-Coding Rnas And Heterogeneous Nuclear Ribonucleoproteins In Regulating Cellular Functions, Xinghui Sun, Mohamed Sham Shihabudeen Haider Ali, Matthew Moran
Department of Biochemistry: Faculty Publications
Long non-coding RNAs (lncRNAs) are emerging as critical regulators of various biological processes and human diseases. The mechanisms of action involve their interactions with proteins, RNA and genomic DNA. Most lncRNAs display strong nuclear localization. Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a large family of RNA-binding proteins that are important for multiple aspects of nucleic acid metabolism. hnRNPs are also predominantly expressed in the nucleus. This review discusses the interactions of lncRNAs and hnRNPs in regulating gene expression at transcriptional and post-transcriptional levels or by changing genomic structure, highlighting their involvements in glucose and lipid metabolism, immune response, DNA damage response, …
Low-Cost Diagnostics: A Novel Aptamer Screening Process,
2017
Purdue University
Low-Cost Diagnostics: A Novel Aptamer Screening Process, Junkai Xie, Kalie Janece Dicks, Oscar C. Sanchez-Medina, Chongli Yuan
The Summer Undergraduate Research Fellowship (SURF) Symposium
Low-Cost diagnostic and screening tools are of vital importance for low resources countries like those in Africa. DNA aptamers are becoming an important detection analytical tool to recognize small molecule targets, drugs and metabolites. Compared to alternative recognition motifs, such as antibody, protein and peptides, aptamers are cheaper to produce via chemical synthesis, stable at room temperature and relatively faster in R&D lead time (year). Over the past 15 years, various aptamer based sensors have been developed. Conventionally, aptamers were screened via a Systematic Evolution of Ligands by EXponential enrichment(SELEX) process. We have improved the SELEX process to improve the …
Establishing A Lung Model For Evaluation Of Engineered Lung Microbiome Therapies,
2017
Purdue University
Establishing A Lung Model For Evaluation Of Engineered Lung Microbiome Therapies, Kathryn F. Atherton, Stephen Miloro, Jenna Rickus
The Summer Undergraduate Research Fellowship (SURF) Symposium
Benzene, a toxin and carcinogen found in air polluted by cigarette smoke, car exhaust, and industrial processes, is associated with the development of leukemia and lymphoma. Other than avoiding exposure, there is no current method to deter the effects of benzene. One potential strategy to prevent these effects is to engineer the bacteria of the human lung microbiome to degrade benzene. To evaluate this novel approach, we must verify that the bacteria remain viable within the lung microenvironment. To do so, lungs were harvested from rats and swabbed to determine the contents of the original lung microbiome. Then green fluorescent …
Fret Biosensors: Engineering Fluorescent Proteins As Biological Tools For Studying Parkinson’S Disease,
2017
Purdue University
Fret Biosensors: Engineering Fluorescent Proteins As Biological Tools For Studying Parkinson’S Disease, Nathan J. Leroy, Jacob R. Norley, Saranya Radhakrishnan, Mathew Tantama
The Summer Undergraduate Research Fellowship (SURF) Symposium
Parkinson’s Disease (PD) is a common neurodegenerative disease with over 200,000 new cases each year. In general, the cause of the disease is unknown, but oxidative stress inside of neurons has been associated with the disease’s pathology for some time. Currently, techniques to study the onset of PD inside of neurons are limited. This makes treatments and causes difficult to discover. One solution to this has been fluorescent protein biosensors. In short, these proteins can be engineered to glow when a certain state is achieved inside a cell. The present research discusses the engineering of a genetically-encoded fluorescent protein (FP) …
Metabolic Comparison Of Wild-Type And Transgenic Synechocystis Pcc 6803 Cyanobacteria,
2017
Purdue University
Metabolic Comparison Of Wild-Type And Transgenic Synechocystis Pcc 6803 Cyanobacteria, Ian A. Mcluckey, John A. Morgan, Joel Yu King Hing
The Summer Undergraduate Research Fellowship (SURF) Symposium
The Calvin-Benson (CBB) cycle is an essential part of nature. This phenomenon allows carbon molecules in carbon dioxide from the atmosphere to be converted into useful energy in the form of sugars. Cyanobacteria are single-celled organisms capable of utilizing energy from sunlight to drive this cycle and are also readily engineered. In hopes of improving this cycle, we compared a wild-type version of the Synechocystis PCC6803 cyanobacteria to an engineered version overexpressing the enzyme FBA (fructose-biphosphate aldolase), called 70 glpX, to deduce how the overexpressing strain is able to be more photosynthetically efficient. To do this, comparative metabolomics were done …
The Response Of Schwann Cells To Weak Dc Electric Fields,
2017
Purdue University
The Response Of Schwann Cells To Weak Dc Electric Fields, Alexander T. Lai, Jianming Li
The Summer Undergraduate Research Fellowship (SURF) Symposium
Schwann cells are glial cells that serve the vital role of supporting neurons in the peripheral nervous system. While their primary function is to provide insulation (myelin) for axons, they also help regenerate injured axons by digesting severed axons and providing scaffolding to guide the regeneration process. This specific role of Schwann cells makes them highly important cellular targets following nerve injury. Although some efforts have been made to encourage Schwann cell migration after nerve damage, the use of electric fields to control cell responses remain unexplored; therefore, this experiment serves to characterize the behavior of Schwann cells to weak …
Fluorescent Protein Biosensor For Use In Parkinson's Research,
2017
Purdue University
Fluorescent Protein Biosensor For Use In Parkinson's Research, Piper R. Miller, Keelan Trull, Mathew Tantama
The Summer Undergraduate Research Fellowship (SURF) Symposium
Purinergic signaling is a type of extracellular communication that occurs between cells, mediated by adenosine triphosphate (ATP), adenosine diphosphate (ADP), and adenosine. In Parkinson’s Disease, purinergic signaling is disrupted, which contributes to neurodegeneration. In order to monitor this change in cell-to-cell signaling, there is a need for the development of a fluorescent protein (FP) biosensor to study the changes in the concentration of the signaling molecule ATP and its decomposition bioproduct ADP. This summer a genetically encoded ADP sensor that measures changes in ADP concentration was developed. This sensor utilizes Forster Resonance Energy Transfer (FRET) which is a sensing technique …
Gas-Based Perfusion Fmri Cerebrovascular Reactivity Maps And Time Of Arrival Maps,
2017
Purdue University
Gas-Based Perfusion Fmri Cerebrovascular Reactivity Maps And Time Of Arrival Maps, Jinxia Yao, Yunjie Tong, Matthew Robert Derdak
The Summer Undergraduate Research Fellowship (SURF) Symposium
Perfusion MRI is a promising tool used in assessing stroke, brain tumors, and patients with neurodegenerative diseases. However, common perfusion MRI techniques have several disadvantages, such as using exogenous contrast agents, low signal-to-noise ratio and long acquisition time. In this study, we used a computer-controlled gas delivery system RespirAct TM. This system provides a reliable carbon dioxide based vasoactive stimulus. This stimulus will immediately generate large and reliable functional magnetic resonance imaging (fMRI) signals, which can be used for perfusion imaging. Each subject was required to have three sequential magnetic resonance imaging (MRI) scans, which are structural scan, resting state …
Identification And Metabolite Profiling Of Chemical
Activators Of Lipid Accumulation In Green Algae,
2017
University of Nebraska-Lincoln
Identification And Metabolite Profiling Of Chemical Activators Of Lipid Accumulation In Green Algae, Nishikant Wase, Boqiang Tu, James Allen, Paul N. Black, Concetta Dirusso
Department of Biochemistry: Faculty Publications
Microalgae are proposed as feedstock organisms useful for producing biofuels and coproducts. However, several limitations must be overcome before algae-based production is economically feasible. Among these is the ability to induce lipid accumulation and storage without affecting biomass yield. To overcome this barrier, a chemical genetics approach was employed in which 43,783 compounds were screened against Chlamydomonas reinhardtii, and 243 compounds were identified that increase triacylglyceride (TAG) accumulation without terminating growth. Identified compounds were classified by structural similarity, and 15 were selected for secondary analyses addressing impacts on growth fitness, photosynthetic pigments, and total cellular protein and starch concentrations. TAG …
Using Silkworms As A Host To Spin Spider Silk-Like Fibers,
2017
Utah State University
Using Silkworms As A Host To Spin Spider Silk-Like Fibers, Xiaoli Zhang
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Using silkworms as the potential host to spin spider silk-like fibers is an area of intense research world-wide. The conventional methods used to create transgenic silkworms hosting spider silk-like gene limits the incorporation of spider silk-like protein and do not improve the mechanical performance of the composite silkworm/spider silk fibers. In this dissertation, synthetic spider ampullate genes were incorporated into the precise site of the fibroin heavy chain or light chain using the latest genome editing technology CRISPR/cas9 guided non-homologous end joining as opposed to conventional random integration using transposon-based piggyBac system. These protocols, with extensive applicability to other silkworm …
Decision Making Processes For A Patient With Cardiac Pacemaker Admitted To The Accident And Emergency Undergoing Magnetic Resonance Imaging – A Case Study,
2017
Universiti Brunei Darussalam
Decision Making Processes For A Patient With Cardiac Pacemaker Admitted To The Accident And Emergency Undergoing Magnetic Resonance Imaging – A Case Study, Raditya F. P.
ASEAN Journal on Science and Technology for Development
This case study aims to apply the processes of decision-making for magnetic resonance imaging (MRI) as a diagnostic examination for a patient with cardiac pacemaker admitted to a private hospital in the capital of Indonesia. It also aims to examine and evaluate the case of a 53-year-old mother who had a heart abnormality that has a pacemaker for one year and was diagnosed to do an MRI examination because of a suspected tumor on the wrist area.The three basic models of decision-making — the descriptive, prescriptive and normative — were applied. The prescriptive used the information processing theory, while the …
Editorial Board,
2017
Universiti Brunei Darussalam
Editorial Board, Ajstd Editorialboard
ASEAN Journal on Science and Technology for Development
No abstract provided.
Decision Making Processes For A Pregnant Woman Admitted To The Accident And Emergency Department Requiring Emergency Diagnostic X-Ray – A Case Study,
2017
Universiti Brunei Darussalam
Decision Making Processes For A Pregnant Woman Admitted To The Accident And Emergency Department Requiring Emergency Diagnostic X-Ray – A Case Study, Ismanto S.
ASEAN Journal on Science and Technology for Development
The objective of this study is to apply the decision-making processes for a pregnant woman who was involved in a motor vehicle accident and admitted to a private middle-class hospital in the capital of Indonesia requiring radiologic X-ray examination. It also aims to examine and evaluate the patient who was in her 20th week of gestation in order to provide her with the best emergency care, diagnostic investigations and treatments.The descriptive, normative and prescriptive models of decision-making are demonstrated. The descriptive model used intuition, while the normative model used decision trees as decision options and lastly the prescriptive decision used …
Phase Manifestation And Formation Of Nanoemulsions Composed Of Imidazolium-Based Ionic Liquid, Tween 80/Span 80 And Labrafac Lipophile Wl 1349,
2017
Universiti Brunei Darussalam
Phase Manifestation And Formation Of Nanoemulsions Composed Of Imidazolium-Based Ionic Liquid, Tween 80/Span 80 And Labrafac Lipophile Wl 1349, Ng S. H., Woi P. M., Eng C. C.
ASEAN Journal on Science and Technology for Development
onic liquids (ILs) can enhance topical and transdermal delivery, as well as increase the solubility of sparingly soluble drugs. In the present work, pseudo-ternary phase diagrams of emulsions were composed of a mixture of non-ionic surfactants, polyoxyethylene sorbitan monooleate (Tween 80®) and sorbitan monooleate (Span 80®) in weight fraction: 1:1, 1:2, 2:1 and 2:3, LabrafacTM Lipophile WL 1349 as an oil phase and 1-hexyl-3-methylimidazolium chloride [(HMIM) (Cl)] as a continuous phase. Emulsion formulations were selected with 10% surfactants from the pseudo-ternary phase diagrams and further prepared at 298.2 ± 0.1 K. Acoustic emulsificationmethod was used to prepare nanoemulsions that were …
Utilization Of Waste From Natural Rubber Glove Manufacturing Line,
2017
Universiti Brunei Darussalam
Utilization Of Waste From Natural Rubber Glove Manufacturing Line, Devaraj V., Nur F. I., Dayang A. I. H., Nor H. K., Zairossani M. N.
ASEAN Journal on Science and Technology for Development
Malaysia is the largest producer and exporter of examination and surgical gloves in the world and currently faced with mitigating large amounts of waste generated during the glove production process. This waste is mainly generated from glove dipping tanks and is referred as dipping tank coagulum (DTC). It is considered as scheduled waste which requires mandatory disposal by incineration, in compliance to the Scheduled Waste Regulations set by the Department of Environment. Work described in this study showed, DTC samples with a polymer content of >40%, both ash and calcium carbonate content of <10% and curatives <2% (Sulphur, antioxidants, accelerators and ZnO) when blended with virgin rubbers (SMR 10 and SMR 20) were found to be suitable for manufacturing value-added rubber products. DTC samples with polymer contents of <40% and lower in curativescould still be considered for recycling, by adding higher portions of virgin rubber for manufacturing products like shoe soles, carpet underlay and thermoplastic elastomer products. Glove manufactures should ideally set up on-site DTC processing facilities at their factory premises equipped with crepers as well as space to ‘air dry’ the creped DTC samples. Creped samples could be sent to the Malaysian Rubber Board (MRB) for chemical analyses. Factory owners could also present the analytical results from MRB to the recyclers to obtain a good premium for their processed DTC samples to be used as raw materials.
