Open Access. Powered by Scholars. Published by Universities.®

Biotechnology Commons™

Open Access. Powered by Scholars. Published by Universities.®

3,204 Full-Text Articles 8,860 Authors 1,219,756 Downloads 220 Institutions

All Articles in Biotechnology

Faceted Search

3,204 full-text articles. Page 100 of 143.

Chemical Precipitation And Coatings Of Tin Selenide, Zainal Z, Saravanan N, Anuar K, Husein M.Z, Yunus W.M.M 2017 Universiti Brunei Darussalam

Chemical Precipitation And Coatings Of Tin Selenide, Zainal Z, Saravanan N, Anuar K, Husein M.Z, Yunus W.M.M

ASEAN Journal on Science and Technology for Development

Tin selenide were prepared chemically in alkaline aqueous solution. The crystalline powder was coated onto microscope glass slides using polyvinyl alcohol solution. The coatings were subjected to annealing at various temperatures to study the effect towards the structure, morphology and composition of the material. The product prepared was characterised using various techniques. The photoresponse for the samples were also studied. The photoelectrochemical (PEC) cell configuration was p-SnSe | (0.01 M K4Fe(CN)6¾0.01 M K3Fe(CN)6.3H2O¾0.1 M Na2SO4| Pt).


Optical Response Of Poly (1,4-Phenylene-1,2-Di (P-Phenoxyphenyl) Vinylene) Towards Oxygen Gas, Mehamod F.S, Daik R, Ahmad M 2017 Universiti Brunei Darussalam

Optical Response Of Poly (1,4-Phenylene-1,2-Di (P-Phenoxyphenyl) Vinylene) Towards Oxygen Gas, Mehamod F.S, Daik R, Ahmad M

ASEAN Journal on Science and Technology for Development

This research involved the synthesis of poly (1,4-phenylene-1,2-di (p-phenoxyphenyl) vinylene), dpop-PDV from di (p-phenoxybenzoyl) benzene compound as the monomer. The potential of the produced polymer as sensing reagent for O2 detection based on fluorescence quenching was studied. Di (p-phenoxybenzoyl) benzene was synthesised via the Friedel-Crafts benzoylationwith terephthaloydichloride and biphenylether as starting materials and anhydrous AlCl3 as the catalyst, while the dpop-PDV was synthesized via the McMurry coupling reaction. The polymerization was carried out in THF with TiCl4 and Zn as the catalyst and reducing agent respectively. Characterization on monomer and polymer had been carried out by using FTIR, GCMS, DSC, …


Mesoporous Inorganic Membrane Reactor For Oxidative Coupling Of Methane, May N.C, Mohamed A.R, Bhatia S 2017 Universiti Brunei Darussalam

Mesoporous Inorganic Membrane Reactor For Oxidative Coupling Of Methane, May N.C, Mohamed A.R, Bhatia S

ASEAN Journal on Science and Technology for Development

The mesoporous inorganic membrane has been developed and characterized for oxidative coupling of methane reactions. In this research, g-alumina membrane was modified with Lanthanum. The membrane has shown thermal stability in prolonged exposure to the high-temperature application of 600-900°C. The results were confirmed by TGA and OCM experimentations. TGA results showed only 2-3% loss from an initial weight that is mainly due to evaporation of water and release of the nitrate compound. The membrane was also found stable for at least a month of operationwhile the catalyst was being regenerated to regain its activity. The SEM cross-sections show successful deposition …


Characterization Of Lignin Precipitated From The Soda Black Liquor Of Oil Palm Empty Fruit Bunch Fibers By Various Mineral Acids, Mohamad Ibrahim M.N, Chuah S.B, Wan Rosli W.D. 2017 Universiti Brunei Darussalam

Characterization Of Lignin Precipitated From The Soda Black Liquor Of Oil Palm Empty Fruit Bunch Fibers By Various Mineral Acids, Mohamad Ibrahim M.N, Chuah S.B, Wan Rosli W.D.

ASEAN Journal on Science and Technology for Development

Soda lignin from oil palm empty fruit bunch was directly isolated by various mineral acids i.e. sulfuric acid, hydrochloric acid, phosphoric acid and nitric acid at three levels of concentration (20% v/v, 60%v/v and concentrated). A comparison study was performed through physicochemical properties and structural features using FT-IR, UV, 13C-NMR and nitrobenzene oxidation. The FT-IR results showed that there is no significant difference between the main structures of the lignin isolated by various acids. However, low concentration of phosphoric acid is preferable because of its highest yield. The S: V: H ratio of 7-15:6-11:1 as evaluated by the nitrobenzene oxidation …


Cathodic Electrodeposition And Characterization Of Ni3se2 Thin Films, Anuar K, Zainal Z, Saravanan N, Kartini A.R 2017 Universiti Brunei Darussalam

Cathodic Electrodeposition And Characterization Of Ni3se2 Thin Films, Anuar K, Zainal Z, Saravanan N, Kartini A.R

ASEAN Journal on Science and Technology for Development

Nickel selenide thin films have been potentiostatically electrodeposited on titanium substrate at room temperature from aqueous solution containing Ni-EDTA and Na2SeO3. Various deposition potentials were attempted in order to determine the optimum electrodeposition potential. The films were characterised using x-ray diffraction analysis (XRD) and the photoactivity of the electrosynthesised films were studied using linear sweep voltammetry (LSV). The band-gap energy was determined using UV-visible spectroscopy. The XRD analysis indicated the formationof polycrystalline Ni3Se2. The film exhibited p-type semiconductor behaviour with good photosensitivity. The bandgap energy (Eg) was about 1.4eV.


Associations Of Common -Thalassemia Mutations With -Globin Gene Frameworks In Northern Thailand, Sanguansermsri P, Shimbu D, Wongvilairat R, Sanguansermsri T 2017 Universiti Brunei Darussalam

Associations Of Common -Thalassemia Mutations With -Globin Gene Frameworks In Northern Thailand, Sanguansermsri P, Shimbu D, Wongvilairat R, Sanguansermsri T

ASEAN Journal on Science and Technology for Development

This study aimed to characterize polymorphism of the b-globin gene (framework) among common b-thalassemia mutations found in northern Thailand. Thirty-one homozygous b-thalassemia major patients admitted to Chiang Mai University Hospital were identified using direct DNA sequencing method. Among 15 patients with homozygous of codon 41/42 (-TCTT), eight were homozygous of framework 1 (FW1), one was homozygous of FW3A, and the remainders were heterozygousof FW1 and FW3A. The gene frequencies of FW1 and FW3A in the patients were 0.733 (22/ 30) and 0.267 (8/30), respectively. All 11 patients with homozygous of codon 17 (A-T) were homozygous of FW3A, while three patients …


Dynamic Mechanical Thermal Analysis (Dmta) Of Thermoplastic Natural Rubber (Tpnr) Barium Ferrite (Bafe12o19) Composites, Hamdan S, Hasihim D.M.A, Yusop M 2017 Universiti Brunei Darussalam

Dynamic Mechanical Thermal Analysis (Dmta) Of Thermoplastic Natural Rubber (Tpnr) Barium Ferrite (Bafe12o19) Composites, Hamdan S, Hasihim D.M.A, Yusop M

ASEAN Journal on Science and Technology for Development

filled with 0-6 volume percentage of barium ferrite was performed using a Polymer Laboratory- Dynamic Mechanical Thermal Analyser (PL-DMTA) over a range of temperature from -100 to 100°C at 10hz. The results showed that the storage modulus (E') of the composites below the transition temperature increase with filler content up to ~3-4 volume percentage. Incorporation of the filler does not change the matrix glass transition that occurs around -40°C but the damping curve becomes broader with increasing filler content. The addition of filler in the compositedoes not affect the glass transition and melting temperature. The blend of TPNR and barium …


Newest Kid On The Block: Characterization Of The Novel Multidrugresistant Pathogen, Candida Auris, Lindsey Masone, Susanna Mirabelli 2017 Long Island University

Newest Kid On The Block: Characterization Of The Novel Multidrugresistant Pathogen, Candida Auris, Lindsey Masone, Susanna Mirabelli

Discovery Day (formerly Post & Beyond)

Candida auris is a novel and emerging fungal pathogen capable of causinginvasive, and often fatal, bloodstream and wound infections in immunocompromised patients. Several outbreaks have been reported in hospitals across the world, including the United States, and predominantly in New York. C.auris exhibits extensive multidrug resistance that has never been seen in any Candida species, and is often misdiagnosed for other Candida species, thus limiting treatment options for patients. Our laboratory obtained 10 C. auris isolates in order to perform in vitro antifungal susceptibility testing and determine the Minimum Inhibitory Concentration (MIC) under Clinical and Laboratory Standards Institute guidelines. …


Is Tb Testing Associated With Increased Blood Interferon-Gamma Levels?, Aideen E. Kennedy, Jim O'Mahony, Noel Byrne, John MacSharry, Riona G. Sayers 2017 Animal & Bioscience Research Department, Animal & Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, Co. Cork Ireland and Department of Biological Sciences, Cork Institute of Technology, Bishopstown, Co. Cork, Ireland

Is Tb Testing Associated With Increased Blood Interferon-Gamma Levels?, Aideen E. Kennedy, Jim O'Mahony, Noel Byrne, John Macsharry, Riona G. Sayers

Department of Biological Sciences Publications

The Republic of Ireland reports a relatively low prevalence of Johne’s disease (JD) compared to international counterparts. Postulated reasons for this include a lower average herd size and a grass-based production system. Ireland also engages in high levels of bovine tuberculosis (bTB) testing. As interferon-gamma (IFN-γ) is believed to play a key role in protecting against JD, it is our hypothesis that administration of purified protein derivative (PPD), as part of the bTB test, is associated with a systemic increase in IFN-γ production, which may potentially limit clinical progression of the disease. We studied 265 cows (202 Friesian and 63 …


Ydj1 Governs Fungal Morphogenesis And Stress Response, And Facilitates Mitochondrial Protein Import Via Mas1 And Mas2, Jinglin L. Xie, Iryna Bohovych, Erin O.Y. Wong, Jean-Philippe Lambert, Anne-Claude Gingras, Oleh Khalimonchuk, Leah E. Cowen, Michelle D. Leach 2017 University of Aberdeen

Ydj1 Governs Fungal Morphogenesis And Stress Response, And Facilitates Mitochondrial Protein Import Via Mas1 And Mas2, Jinglin L. Xie, Iryna Bohovych, Erin O.Y. Wong, Jean-Philippe Lambert, Anne-Claude Gingras, Oleh Khalimonchuk, Leah E. Cowen, Michelle D. Leach

Department of Biochemistry: Faculty Publications

Mitochondria underpin metabolism, bioenergetics, signalling, development and cell death in eukaryotes. Most of the ~1,000 yeast mitochondrial proteins are encoded in the nucleus and synthesised as precursors in the cytosol, with mitochondrial import facilitated by molecular chaperones. Here, we focus on the Hsp40 chaperone Ydj1 in the fungal pathogen Candida albicans, finding that it is localised to both the cytosol and outer mitochondrial membrane, and is required for cellular stress responses and for filamentation, a key virulence trait. Mapping the Ydj1 protein interaction network highlighted connections with co-chaperones and regulators of filamentation. Furthermore, the mitochondrial processing peptidases Mas1 and …


Plant Variety In The Republic Of Korea: Seed Industry Law, Yoonjin Buyn 2017 University of Oklahoma College of Law

Plant Variety In The Republic Of Korea: Seed Industry Law, Yoonjin Buyn

Oklahoma Journal of Law and Technology

No abstract provided.


The European Patent Office And The European Patent: An Open Avenue For Biotechnologists And "Living Inventions", Katrina McClatchey 2017 University of Oklahoma College of Law

The European Patent Office And The European Patent: An Open Avenue For Biotechnologists And "Living Inventions", Katrina Mcclatchey

Oklahoma Journal of Law and Technology

No abstract provided.


Agricultural Biogechnology: United States Statutory Law, Jo Lynn Jeter 2017 University of Oklahoma College of Law

Agricultural Biogechnology: United States Statutory Law, Jo Lynn Jeter

Oklahoma Journal of Law and Technology

No abstract provided.


The International Treaty On Plant Genetic Resources For Food And Agriculture: Friend Of The International Farmer, Steven M. Ruby 2017 University of Oklahoma College of Law

The International Treaty On Plant Genetic Resources For Food And Agriculture: Friend Of The International Farmer, Steven M. Ruby

Oklahoma Journal of Law and Technology

No abstract provided.


The Effect Of The "Onco-Mouse" Decisions On The Exception To Patentability For "Animal Varieties" Under The European Patent Convention, Katrina McClatchey 2017 University of Oklahoma College of Law

The Effect Of The "Onco-Mouse" Decisions On The Exception To Patentability For "Animal Varieties" Under The European Patent Convention, Katrina Mcclatchey

Oklahoma Journal of Law and Technology

No abstract provided.


The Impact Of Novartis On The European Patent Convention's Exception To Patentability For "Plant Varieties", Katrina McClatchey 2017 University of Oklahoma College of Law

The Impact Of Novartis On The European Patent Convention's Exception To Patentability For "Plant Varieties", Katrina Mcclatchey

Oklahoma Journal of Law and Technology

No abstract provided.


Agricultural Biotechnology: United States Case Law, Jo Lynn Jeter 2017 University of Oklahoma College of Law

Agricultural Biotechnology: United States Case Law, Jo Lynn Jeter

Oklahoma Journal of Law and Technology

No abstract provided.


Identification Of Potential Tissue-Specific Cancer Biomarkers And Development Of Cancer Versus Normal Genomic Classifiers, Akram Mohammed, Greyson Biegert, Jiri Adamec, Tomáš Helikar 2017 University of Nebraska-Lincoln

Identification Of Potential Tissue-Specific Cancer Biomarkers And Development Of Cancer Versus Normal Genomic Classifiers, Akram Mohammed, Greyson Biegert, Jiri Adamec, Tomáš Helikar

Department of Biochemistry: Faculty Publications

Machine learning techniques for cancer prediction and biomarker discovery can hasten cancer detection and significantly improve prognosis. Recent “OMICS” studies which include a variety of cancer and normal tissue samples along with machine learning approaches have the potential to further accelerate such discovery. To demonstrate this potential, 2,175 gene expression samples from nine tissue types were obtained to identify gene sets whose expression is characteristic of each cancer class. Using random forests classification and ten-fold cross-validation, we developed nine single-tissue classifiers, two multi-tissue cancer-versus-normal classifiers, and one multi-tissue normal classifier. Given a sample of a specified tissue type, the single-tissue …


Organ-Specific Regulation Of Atp7a Abundance Is Coordinated With Systemic Copper Homeostasis, Haarin Chun, Tracy Catterson, Heejeong Kim, Jaekwon Lee, Byung-Eun Kim 2017 University of Maryland

Organ-Specific Regulation Of Atp7a Abundance Is Coordinated With Systemic Copper Homeostasis, Haarin Chun, Tracy Catterson, Heejeong Kim, Jaekwon Lee, Byung-Eun Kim

Department of Biochemistry: Faculty Publications

Copper (Cu) is an essential cofactor for various enzymatic activities including mitochondrial electron transport, iron mobilization, and peptide hormone maturation. Consequently, Cu dysregulation is associated with fatal neonatal disease, liver and cardiac dysfunction, and anemia. While the Cu transporter ATP7A plays a major role in both intestinal Cu mobilization to the periphery and prevention of Cu over-accumulation, it is unclear how regulation of ATP7A contributes to Cu homeostasis in response to systemic Cu fluctuation. Here we show, using Cu-deficient mouse models, that steadystate levels of ATP7A are lower in peripheral tissues (including the heart, spleen, and liver) under Cu deficiency …


Characterization Of Different Molecular Markers For Identification Of Salmonella Enterica Serovar Typhi In Pakistani Population, Faizan Muttiullah, Fida Muhammad Khan, Fakhar-i- Abbas, Sabiha Shamim 2017 Institute of Natural and Management Sciences (INAM), Rawalpindi

Characterization Of Different Molecular Markers For Identification Of Salmonella Enterica Serovar Typhi In Pakistani Population, Faizan Muttiullah, Fida Muhammad Khan, Fakhar-I- Abbas, Sabiha Shamim

Journal of Bioresource Management

Typhoid is caused by Salmonella enterica serovar Typhi that is usually diagnosed by using serologic and immuno-chromatographic techniques in developing counties including Pakistan, which is thought to be an unreliable diagnostic method. For accurate diagnosis we used molecular techniques to amplify 204 bp StyR-36 and 498 bp flagellin gene for the identification of Salmonella enterica serovar Typhi. This study was done on 58 individuals diagnosed positive of typhoid via serologic tests and 50 healthy individuals as a control group. Success rate of amplification for flagellin gene was 77.58% while that for StyR-36 gene was 68.97% showing that flagellin gene primer …


Digital Commons powered by bepress