Ocular Gene Transfer In The Spotlight: Implications Of Newspaper Content For Clinical Communications, 2024 University of Alberta, Canada
Ocular Gene Transfer In The Spotlight: Implications Of Newspaper Content For Clinical Communications, Shelly Benjaminy, Tania M. Bubela
Office of the Provost
Background: Ocular gene transfer clinical trials are raising hopes for blindness treatments and attracting media attention. News media provide an accessible health information source for patients and the public, but are often criticized for overemphasizing benefits and underplaying risks of novel biomedical interventions. Overly optimistic portrayals of unproven interventions may influence public and patient expectations; the latter may cause patients to downplay risks and over-emphasize benefits, with implications for informed consent for clinical trials. We analyze the news media communications landscape about ocular gene transfer and make recommendations for improving communications between clinicians and potential trial participants in light of …
Dynamic Metabolic Flux Analysis Amidst Data Variability: Sphingolipid Biosynthesis Case Study In Arabidopsis Thaliana Cell Cultures, 2024 University of Nebraska-Lincoln
Dynamic Metabolic Flux Analysis Amidst Data Variability: Sphingolipid Biosynthesis Case Study In Arabidopsis Thaliana Cell Cultures, Abraham Boluwatife Osinuga
Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research
Sphingolipids are pivotal for plant development and stress responses. Growing interest has been directed towards fully comprehending the regulatory mechanisms of the sphingolipid pathway. In this study, we explore its de novo biosynthesis and homeostasis in Arabidopsis thaliana cell cultures, shedding light on fundamental metabolic mechanisms. Employing 15N isotope labeling and quantitative dynamic modeling approach, we obtained data with notable variations and developed a regularized and constraint-based Dynamic Metabolic Flux Analysis (r-DMFA) framework to predict metabolic shifts due to enzymatic changes. Our analysis revealed key enzymes such as sphingoid-base hydroxylase (SBH) and long-chain-base kinase …
Optimizing The Expression Of Polyethylene Terephtalate Hydrolase-Encoding Synthetic Gene In Escherichia Coli Arctic Express (De3), 2024 Department of Biology, University of Indonesia, Depok 16424, West Java
Optimizing The Expression Of Polyethylene Terephtalate Hydrolase-Encoding Synthetic Gene In Escherichia Coli Arctic Express (De3), Jocelyn Nataniel, Maria Ulfah, Dini Achnafani, Niknik Nurhayati, Gabriela Christy Sabbathini, Sri Rezeki Wulandari, Abinawanto Abinawanto, Is Helianti
Makara Journal of Science
The waste of polyethylene terephthalate (PET) plastic waste in Indonesia is a pressing concern due to its slow degradation and potential environmental damage. One promising solution is to utilize polyethylene terephthalate hydrolase from Ideonella sakaiensis (IsPETase), an enzyme that specifically degrades PET. However, inducing the expression of IsPETase synthetic gene in Escherichia coli BL21 (DE3) has been challenging because much of it remains insoluble. This study aimed to express IsPETase in E. coli Arctic Express (DE3) and optimize the conditions to enhance its production. First, pET22b(+)pelB-IsPETase was inserted into E. coli Arctic Express (DE3). The …
Cultivation Of Chlorella And Chlamydomonas Under Nitrogen Starvation Conditions: Research Of Fatty Acids Production Potential, 2024 CNRDPA, National Center for Research and Development of Fisheries and Aquaculture, Bou-Ismail, Algeria
Cultivation Of Chlorella And Chlamydomonas Under Nitrogen Starvation Conditions: Research Of Fatty Acids Production Potential, Affaf Kord, Samira Chader, Maha Kherrarba, Soumia Benrabah
Journal of Bioresource Management
Microalgae are attracting particular attention because of their use in various fields such as bio-energy. The main objective of this work was to evaluate the effect of stress induced by nitrogen deficiency on the accumulation of lipids in Chlorella sp. and Chlamydomonas sp. isolated from the brackish water of El Golea Lake in the Algerian Sahara. The two species were first cultured in batch in BBM medium under basic conditions (0.75 g/l NaNO
3 ) then under nitrogen stress (0.25 g/l NaNO
3 ). After lipids extraction, the fatty acids were trans-esterified to obtain the fatty acid methyl esters that …
Exploring The Coffee Genome: A Comprehensive Analysis Of The Plant-Specific Dof Transcription Factor Gene Family, 2024 Department of Horticulture, University of the Punjab New campus, Lahore, Pakistan
Exploring The Coffee Genome: A Comprehensive Analysis Of The Plant-Specific Dof Transcription Factor Gene Family, Humera Amin, Shumaila Dastgir, Numan Ali, Muhammad Shafiq, Muhammad Haseeb, Syed Agha Armaghan Asad Abbas Naqvi, Laiba Sharif, Syeda Shehar Bano Rizvi, Sohaib Ahmad, Farooq Ahmad
Journal of Bioresource Management
Dof (DNA binding with one finger) proteins constitute highly ubiquitous transcription factor gene families that are found across all plant species, playing crucial role in fruit ripening, organ development, and other activities. A comprehensive genome-wide analysis of the coffee genome uncovered 49 CaDof genes, which were described in terms of their gene structures, phylogenetic relationships, subcellular localization, gene duplication, and expression in various plant organs. In Coffea arabica, segmental duplication outnumbered tandem duplication. Expressed sequence tags were used to determine the expression of specific organs in CaDof genes. Most genes showed high expression in fruits at various stages, in …
Role Of Plant Metabolites In Curing Neurodegenerative Disorders, 2024 SMART Society
Role Of Plant Metabolites In Curing Neurodegenerative Disorders, Mainak Sarkar, Pratik Talukder
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Microbiome And Gut-Brain Axis Affecting Stress Behavior, 2024 SMART Society
Microbiome And Gut-Brain Axis Affecting Stress Behavior, Shreya Banik, Pinku Chandran Nath, Rupak Roy
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Environmental Toxicants And Autoimmunity, 2024 SMART Society
Environmental Toxicants And Autoimmunity, Susmita Mukherjee, Swagata Mukherjee, Chiranjeeb Dey, Sonali Paul
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Cancer Proteomics: A Stride Through Disease Proteins, 2024 SMART Society
Cancer Proteomics: A Stride Through Disease Proteins, Shrestha Dutta, Rajgourab Ghosh
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Uses Of Metallic Biomaterials As Orthopedic Implants, 2024 SMART Society
Uses Of Metallic Biomaterials As Orthopedic Implants, Agnivesh Sen, Keya De Mukhopadhyay
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Role Of Indian Gooseberry (Phyllanthus Emblica) In Disease Prevention, 2024 SMART Society
Role Of Indian Gooseberry (Phyllanthus Emblica) In Disease Prevention, Sampreeti Chatterjee, Anubrata Bit, Rohan Murmu, Keya De Mukhopadhyay¹
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Turmeric And Cancer Prevention: Unveiling The Potential Of Nature's Golden Spice, 2024 SMART Society
Turmeric And Cancer Prevention: Unveiling The Potential Of Nature's Golden Spice, Rohan Murmu, Keya De Mukhopadhyay
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Smart Crop Management System With Iot And Ml For Disease Detection, Soil, And Air Quality Monitoring, 2024 SMART Society
Smart Crop Management System With Iot And Ml For Disease Detection, Soil, And Air Quality Monitoring, Pratik Taluker, Rajarshi Ray
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Sars-Cov-2 Virus And Its Initial Variants Of Concern (Voc): A Short Communication, 2024 SMART Society
Sars-Cov-2 Virus And Its Initial Variants Of Concern (Voc): A Short Communication, Saptarshi Roy Chowdhury
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Alteration In Immunological Profile During Malignancy: Role Of Environmental Toxicants, 2024 SMART Society
Alteration In Immunological Profile During Malignancy: Role Of Environmental Toxicants, Susmita Mukherjee, Priya Ghosh, Chiranjeeb Dey, Sonali Paul
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Evaluation Of The Water Quality Parameters From Different Point Sources: A Case Study Of West Bengal, 2024 SMART Society
Evaluation Of The Water Quality Parameters From Different Point Sources: A Case Study Of West Bengal, Rupak Roy, Silpi Sarkar, Riddhi Kotak, Duttatreya Nandi, Saurav Shil, Sudatta Singha, Komal Sharma, Sambit Tarafdar
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Malaria Control: A New Idea, 2024 SMART Society
Malaria Control: A New Idea, Biswadeep Chaudhuri
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Natural Treatment Of Mosquito And Organic Pollutants In Shallow Water & Surroundings: A Report, 2024 SMART Society
Natural Treatment Of Mosquito And Organic Pollutants In Shallow Water & Surroundings: A Report, Biswadeep Chaudhuri
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
A Brief Go-To On The Epidemiology Of Malaria And The Usage Of Virus Like Particles (Vlps)As A Novel Immunogenic Vaccine Platform, 2024 SMART Society
A Brief Go-To On The Epidemiology Of Malaria And The Usage Of Virus Like Particles (Vlps)As A Novel Immunogenic Vaccine Platform, Tirtha Tarafdar
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.
Cancer: A Brief Discussion On Risks Causing Cancer And Their Relation With Today’S Lifestyle: A Report, 2024 SMART Society
Cancer: A Brief Discussion On Risks Causing Cancer And Their Relation With Today’S Lifestyle: A Report, Sampreeti Chatterjee
American Journal of Applied Bio-Technology Research (AJABTR)
No abstract provided.