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Articles 4231 - 4260 of 4871
Full-Text Articles in Medicine and Health Sciences
Pathophysiological Significance Of Blood Rheology, Oğuz Keri̇m Başkurt
Pathophysiological Significance Of Blood Rheology, Oğuz Keri̇m Başkurt
Turkish Journal of Medical Sciences
Tissue perfusion is determined by both blood vessel geometry and the rheological properties of blood. Blood is a non-Newtonian fluid, its viscosity being dependent on flow conditions. Blood and plasma viscosities, as well as the rheological properties of blood cells (e.g., deformability and aggregation of red blood cells), are influenced by disease processes and extreme physiological conditions. These rheological parameters may in turn affect the blood flow in vessels, and hence tissue perfusion. Unfortunately it is not always possible to determine if a change in rheological parameters is the cause or the result of a disease process. The hemorheology-tissue perfusion …
Ventilator Associated Pneumonia In Critically Ill Patients: Prevention And Treatment, Argyris Michalopoulos, Stefanos Geroulanos
Ventilator Associated Pneumonia In Critically Ill Patients: Prevention And Treatment, Argyris Michalopoulos, Stefanos Geroulanos
Turkish Journal of Medical Sciences
No abstract provided.
Effects Of Acute Hypoxia On Body Substrate Utilisation During Progressively Increasing Work Rate Exercise Tests, Oğuz Özçeli̇k, Hali̇l Doğan, Haluk Keleşti̇mur
Effects Of Acute Hypoxia On Body Substrate Utilisation During Progressively Increasing Work Rate Exercise Tests, Oğuz Özçeli̇k, Hali̇l Doğan, Haluk Keleşti̇mur
Turkish Journal of Medical Sciences
Respiratory quotient (RQ) was used to assess the effectiveness of exercise interventions in shifting substrate utilisation. The body's RQ can be estimated non-invasively from the ratio of CO_2 production to O_2 consumption. In the present study, we examined the effects of acute hypoxia on the substrate utilisation of the body and its non-invasive estimation from ventilatory and pulmonary gas exchange variables during exercise. Eight male subjects performed two progressively increasing work rate exercise tests (15 W/min) until the limit of tolerance: in one test they were breathing room air (normoxia) and in the other 12% O_2 (hypoxia). Ventilatory and pulmonary …
Secondary Malignancies After Hemopoietic Stem Cell Transplantation, H.Joachim Deeg, Jeffrey L. Schwartz, Debbie Friedman, Wendy Leisenring
Secondary Malignancies After Hemopoietic Stem Cell Transplantation, H.Joachim Deeg, Jeffrey L. Schwartz, Debbie Friedman, Wendy Leisenring
Turkish Journal of Medical Sciences
Hemopoietic stem cell transplantation is being carried out for rapidly increasing numbers of patients. Survival probabilities have increased progressively, and most patients return to productive lives. However, delayed complications do occur. Here, we review the incidence and spectrum of post-transplant malignancies, discuss risk factors and mechanisms, and assess the efficacy of therapeutic interventions.
Effects Of Ramadan Fasting On Stroke, Selçuk Çomoğlu, Ahmet Temi̇zhan, Emel Peşi̇nci̇, İzzet Tandoğan, Şenay Özbakir
Effects Of Ramadan Fasting On Stroke, Selçuk Çomoğlu, Ahmet Temi̇zhan, Emel Peşi̇nci̇, İzzet Tandoğan, Şenay Özbakir
Turkish Journal of Medical Sciences
The effects of fasting on humans have not been adequately investigated. Ramadan fasting is a great opportunity for scientific research due to its peculiar nature. With this in mind, we conducted research on the effects of Ramadan on stroke, which is one of the most common causes of death in adults. Patients hospitalized solely for ischemic stroke and intracerebral hemorrhage were evaluated retrospectively. The ratio of these cases to other patients hospitalized in the neurology department was determined. The in-hospital clinical course and mortality rates of the patients with stroke were evaluated. Within the entire cohort, the most frequently encountered …
Expression Of The Tumour Suppressor Gene P53 In Odontogenic Cysts, Ayla Özveren, Can Tuskan, Mehmet Yaltirik, Beli̇r Atalay, Gülçi̇n Erseven
Expression Of The Tumour Suppressor Gene P53 In Odontogenic Cysts, Ayla Özveren, Can Tuskan, Mehmet Yaltirik, Beli̇r Atalay, Gülçi̇n Erseven
Turkish Journal of Medical Sciences
The protein p53 seems to be related to the suppression of cell proliferation. Positive tissues appear to have a higher proliferative activity than negative tissues. Mutation of the p53 tumour suppressor gene has been demonstrated in a large proportion of human head and neck tumours, although no formal evidence of functional aberration has been shown p53 may have importance during the early stage of malignancy. The aim of this study was to evaluate the role of the p53 tumour suppressor gene in the pathogenesis of odontogenic cysts. Expression of abnormal p53 protein is a widely recognised marker of malignancy. Expression …
Tru-Cut And Fine Needle Aspiration Biopsy Diagnosis Of Lesions Of The Jaws, Namik Kemal Ayhan, Cengi̇zhan Keski̇n, Kerem Dedeoğlu, Mehmet Yaltirik
Tru-Cut And Fine Needle Aspiration Biopsy Diagnosis Of Lesions Of The Jaws, Namik Kemal Ayhan, Cengi̇zhan Keski̇n, Kerem Dedeoğlu, Mehmet Yaltirik
Turkish Journal of Medical Sciences
Nowadays, modern biopsy techniques such as fine and wide needles are used instead of invasive biopsy techniques for examining malign and benign lesions. This study examines whether wide needle biopsy (Tru-cut) possesses advantages as an alternative method to open biopsy. This study was performed on 40 patients with suspicious intra-jaw lesions. An 18-gauge, three-piece biopsy device was used. All the samples were sent to the tumor pathology unit at the oncology institute for histopathologic and cytopathologic examination. Thirty-seven of the 40 samples were adequate for diagnosis and three inadequate were. When we considered the results of Tru-cut and fine needle …
Drug Resistance In Acute Leukaemia And Reversion, Jean-Pierre Marie, Ollivier Legrand
Drug Resistance In Acute Leukaemia And Reversion, Jean-Pierre Marie, Ollivier Legrand
Turkish Journal of Medical Sciences
No abstract provided.
The Ebmt Activity Survey On Hematopoietic Stem Cell Transplantation: A Novel Instrument For Quality Control, Alois Gratwohl, Helen Baldomero, Alvaro Urbano Ispizua
The Ebmt Activity Survey On Hematopoietic Stem Cell Transplantation: A Novel Instrument For Quality Control, Alois Gratwohl, Helen Baldomero, Alvaro Urbano Ispizua
Turkish Journal of Medical Sciences
The hematopoietic stem cell transplant activity survey of the European Group for Blood and Marrow Transplantation (EBMT) represents a novel modern tool in health care management. Introduced in 1990, it captures annual numbers of hematopoietic stem cell transplantation (HSCT) by indication, donor type and stem cell source from each individual European transplant team. Supplemented by demographical data and economic factors, team density and transplant rates can be calculated and the impact of economics on HSCT rates can be assessed. As documented in the present analysis, a total of 19,668 HSCT were performed in Europe in 2001 by 599 teams in …
Development Of A Diagnostic And Screening Elisa System For Measuring Tetanus Antitoxoid Levels, Cemaletti̇n Aybay, Resul Karakuş, Ahmet Gökhan Gündoğdu
Development Of A Diagnostic And Screening Elisa System For Measuring Tetanus Antitoxoid Levels, Cemaletti̇n Aybay, Resul Karakuş, Ahmet Gökhan Gündoğdu
Turkish Journal of Medical Sciences
Tetanus is a vaccine-preventable disease of global importance. When acquired it has a high mortality rate. Screenings of special subpopulations such as women of childbearing age provide important clues about tetanus vaccination coverage, and tools for mass protective measures, e.g, protective measures for neonatal tetanus. In addition to its reliability and sensitivity, the main advantage of a mass-screening tool should be its cost-effectiveness. We aimed to develop a cost-effective and sensitive enzyme-linked immunosorbent assay (ELISA) that can be used for diagnostic research as well as mass screening purposes for antitetanus antibodies. Our in-house antitetanus ELISA was validated and tested for …
A Cell Protective Mechanism In A Murine Model Of Parkinson's Disease, Emi̇n Öztaş, Turgut Topal
A Cell Protective Mechanism In A Murine Model Of Parkinson's Disease, Emi̇n Öztaş, Turgut Topal
Turkish Journal of Medical Sciences
Parkinson's disease is characterized by progressive degeneration of the dopaminergic (DA) neurons in the substantia nigra (SN). However, the mechanism underlying DA cell death remains unclear. While apoptotic cell death has been implicated in DA cell death in Parkinson's disease, autophagy - a regulated cellular process for degrading intracellular proteins and organelles under stress - in Parkinson's disease is not known. Here, we report evidence of autophagy in DA neurons of the SN in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model of Parkinson's disease. Mice were treated with saline or MPTP (40 mg/kg) and sacrificed after 7 days, and brain tissue samples were …
Morphometric Evaluation Of The Foramen Magnum And Variations In Its Shape: A Study On Computerized Tomographic Images Of Normal Adults, Khalil Awadh Murshed, Aynur Emi̇ne Çi̇çekci̇başi, Işik Tuncer
Morphometric Evaluation Of The Foramen Magnum And Variations In Its Shape: A Study On Computerized Tomographic Images Of Normal Adults, Khalil Awadh Murshed, Aynur Emi̇ne Çi̇çekci̇başi, Işik Tuncer
Turkish Journal of Medical Sciences
The purpose of this study was to evaluate the radiological measurements of the foramen magnum (FM) and their relation to sex as well as to note variations in the shape of the FM. Cranial computerized tomographic images (CT) of 110 normal subjects (57 males - 53 females) between the ages of 18 and 80 years were examined in this study. The sagittal and transverse diameters of the FM were measured with a millimetric sliding caliper. Additionally, the area of the FM was also estimated. The statistical analysis for sex comparison was made using Student's t test. To determine the relationships …
The Effects Of Epidural Anesthesia And General Anesthesia On Newborns At Cesarean Section, Ari̇f Yegi̇n, Zeki̇ Ertuğ, Murat Yilmaz, Meli̇ha Erman
The Effects Of Epidural Anesthesia And General Anesthesia On Newborns At Cesarean Section, Ari̇f Yegi̇n, Zeki̇ Ertuğ, Murat Yilmaz, Meli̇ha Erman
Turkish Journal of Medical Sciences
We compared Apgar scores and umblical arterial and venous blood gas samples of infants following the application of general anesthesia or lumbar epidural anesthesia during cesarean section. Sixty-two pregnant women whose babies were to be delivered at term by cesarean section were recruited for this study and randomized to receive either general anesthesia (GA) (n = 31), or lumbar epidural anesthesia (EA) (n = 31). Following delivery, a segment of the umbilical cord was doubly clamped, and arterial and venous blood gas samples were taken. In both groups, Apgar scores were recorded at 1 and 5 min. There were no …
Frequency Of Enuresis, Constipation And Enuresis Association With Constipation In A Group Of School Children Aged 5-9 Years In Malatya, Turkey, Sema Uğuralp, Leyla Karaoğlu, Abdurrahman Karaman, Mehmet Demi̇rcan, Cengi̇z Yakinci
Frequency Of Enuresis, Constipation And Enuresis Association With Constipation In A Group Of School Children Aged 5-9 Years In Malatya, Turkey, Sema Uğuralp, Leyla Karaoğlu, Abdurrahman Karaman, Mehmet Demi̇rcan, Cengi̇z Yakinci
Turkish Journal of Medical Sciences
The aim of this study was to determine the frequency of enuresis, constipation and enuresis associated with constipation in school children aged 5-9 years living in Malatya Municipality, Turkey. This is a descriptive cross-sectional study. All elementary schools in Malatya Municipality with kindergarten and preparatory classes took part in the study. All parents of the children aged 5-9 years enrolled in these schools were given a questionnaire. Completion of the questionnaire was voluntary. Of the parents, 1377 completed the questionnaire and these were evaluated. Overall enuresis frequency was 9.5%. Enuresis frequency was significantly higher among boys (11.2%) compared to girls …
Nicotine Dependence In Medical Students And Physicians In The Lakes Region, Rezan Demi̇ralay
Nicotine Dependence In Medical Students And Physicians In The Lakes Region, Rezan Demi̇ralay
Turkish Journal of Medical Sciences
This study was carried out to evaluate the level of physical nicotine dependence in medical students and physicians working in the Lakes region, Turkey. The standardized Fagerström test of nicotine dependence questionnaire was given to 135 physicians and 61 medical students who smoked daily. The rate of daily smoking was 28.4% in medical students and 33.7% in physicians. Average Fagerström test for nicotine dependence scores were 3.98 ± 2.69 for medical students, 3.69 ± 3.05 for general practitioners, 3.06 ± 2.23 for research assistants and 3.34 ± 2.88 for specialist physicians. Of the medical students, 15 (24.6%) indicated high nicotine …
The Behaviour And Attitude Of Physicians In The Lakes Region Towards Smoking, Rezan Demi̇ralay
The Behaviour And Attitude Of Physicians In The Lakes Region Towards Smoking, Rezan Demi̇ralay
Turkish Journal of Medical Sciences
This study was carried out on 401 physicians who work in the Lakes region, Turkey, to assess their behaviour and attitude towards smoking. A questionnaire based on guidelines and standardised questions prepared by the World Health Organization was given to physicians. Of the physicians, 136 (33.9%) had never tried to smoke in their lives and 45 (11.2%) were former smokers. Of the 220 (54.9%) physicians who had smoked for at least 6 months in their lifetime, 46 (11.5%) were ex-smokers. Of the current smokers, 135 (77.6%) were daily smokers and 39 (22.4%) were occasional smokers. Fifty-two (43.7%) general practitioners, 34 …
The Prevalence Of Chronic Diseases And Quality Of Life In Elderly People In Samsun, Sevgi̇ Canbaz, Ahmet Tevfi̇k Sünter, Sennur Dabak, Yildiz Pekşen
The Prevalence Of Chronic Diseases And Quality Of Life In Elderly People In Samsun, Sevgi̇ Canbaz, Ahmet Tevfi̇k Sünter, Sennur Dabak, Yildiz Pekşen
Turkish Journal of Medical Sciences
The increasing aged population has recently become a focus of interest in developing countries. The aims of our study were to evaluate chronic diseases and measure the quality of life of elderly people in Samsun. A cross-sectional study was conducted between March 1 and April 30,2001. There were 8350 elderly people in the study area. The study group consisted of 835 elderly people, calculated by using the sample size formula. Except for 98 (11.7%) individuals, 737 of 835 elderly people participated in this study. In the first step of the study, the data of 737 elderly people were used, and …
Paraplegia Due To Extramedullary Hematopoiesis In The Thalassemia Intermedia, Şule Peker, Mehmet Çelebi̇soy, İsmai̇l Akkol, Hamdi̇ Bezi̇rci̇oğlu
Paraplegia Due To Extramedullary Hematopoiesis In The Thalassemia Intermedia, Şule Peker, Mehmet Çelebi̇soy, İsmai̇l Akkol, Hamdi̇ Bezi̇rci̇oğlu
Turkish Journal of Medical Sciences
ER^1, Mehmet ÇELEBİSOY^1, İsmail AKKOL^2, Hamdi BEZİRCİOĞLU^2 ^1Atatürk Education and Research Hospital Second Neurology Clinic, İzmir - Turkey ^2Atatürk Education and Research Hospital Neurosurgery Clinic, İzmir - Turkey
Trichorhinophalangeal Syndrome Type I: A Turkish Case, Mustafa Kendi̇rci̇, Mehmet Keski̇n, Duran Aslan, Abdülhaki̇m Coşkun, Yusuf Özkul
Trichorhinophalangeal Syndrome Type I: A Turkish Case, Mustafa Kendi̇rci̇, Mehmet Keski̇n, Duran Aslan, Abdülhaki̇m Coşkun, Yusuf Özkul
Turkish Journal of Medical Sciences
KENDİRCİ^1, Mehmet KESKİN^1, Duran ARSLAN^1, Abdülhakim COŞKUN^2, Yusuf ÖZKUL^3 ^1Department of Pediatrics, Faculty of Medicine, Erciyes University, Kayseri - Turkey ^2Department of Radiodiagnostics, Faculty of Medicine, Erciyes University, Kayseri - Turkey ^3Department of Genetics, Faculty of Medicine, Erciyes University, Kayseri - Turkey
Measurement Of Urine Albumin Levels With A Monoclonal Antibody Based In-House Elisa, Cemaletti̇n Aybay, Resul Karakuş
Measurement Of Urine Albumin Levels With A Monoclonal Antibody Based In-House Elisa, Cemaletti̇n Aybay, Resul Karakuş
Turkish Journal of Medical Sciences
Microalbuminuria is considered to be an early indicator of diabetic nephropathy. We have previously reported the establishment of A-HAlb/98 hybridoma secreting monoclonal antibody that specifically recognizes human serum albumin (HSA). In this report, an in-house enzyme-linked immunosorbent assay (ELISA) was developed using this antibody for the measurement of urinary albumin (UA) and UA was examined in 24 different samples. A-HAlb/98 was used as the capture antibody by immobilizing onto microtitre plates in ELISA format. HSA-specific polyclonal rabbit immunoglobulin was labelled with biotin and then used as the tracer antibody. The dynamic assay range of ELISA for albumin was established to …
Are The Sequence And Level Of The Branches Of The Popliteal Artery Different In The Fetus Than In The Adult?: Two Fetuses With Popliteal Arterial Variation, Zeli̇ha Kurtoğlu, Mustafa Akteki̇n, Ahmet Hakan Öztürk, Cem Kara
Are The Sequence And Level Of The Branches Of The Popliteal Artery Different In The Fetus Than In The Adult?: Two Fetuses With Popliteal Arterial Variation, Zeli̇ha Kurtoğlu, Mustafa Akteki̇n, Ahmet Hakan Öztürk, Cem Kara
Turkish Journal of Medical Sciences
URTOĞLU Mustafa AKTEKİN Ahmet Hakan ÖZTÜRK Cem KARA Department of Anatomy Faculty of Medicine, Mersin University, Mersin - Turkey
Intranasal Encephalocele, Nesri̇n Gürsan, Mehmet Dumlu Aydin, Sare Altaş, Atti̇la Ertaş
Intranasal Encephalocele, Nesri̇n Gürsan, Mehmet Dumlu Aydin, Sare Altaş, Atti̇la Ertaş
Turkish Journal of Medical Sciences
ÜRSAN^1 Mehmet Dumlu AYDIN^2 Sare ALTAŞ^1 Attila ERTAŞ^3 Departments of ^1Pathology, ^2Neurosurgery, Faculty of Medicine, Atatürk University; and ^3Department of Ear-Nose-Throat, Social Security Hospital, Erzurum - Turkey
Quantification Of The Fli1 Gene Expression By Real-Time Quantitative Rt-Pcr, Hakan Savli, Sema Sirma, Uğur Özbek
Quantification Of The Fli1 Gene Expression By Real-Time Quantitative Rt-Pcr, Hakan Savli, Sema Sirma, Uğur Özbek
Turkish Journal of Medical Sciences
In this study, quantification levels were investigated to define alterations in the expression of the FLI1 gene on acute promyelocytic leukemia (APL), which is characterized by a reciprocal t(15,17) translocation of fusing the PML gene to the retinoic acid receptor alpha (RAR alpha) gene. The FLI1 gene plays an important role in several signal transduction pathways, and is involved in the normal regulation of myeloid hematopoiesis and leukomogenesis. We used the real-time quantitative RT-PCR (LightCycler) with SYBR Green I dye method for the labeling and analysis of the quantification of FLI1 gene RT-PCR products. Ribosomal protein S9 (RPS9) was used …
An Assessment Of Femur Growth Parameters In Human Fetuses And Their Relationship To Gestational Age, Taner Zi̇ylan, Khalil Awadh Murshed
An Assessment Of Femur Growth Parameters In Human Fetuses And Their Relationship To Gestational Age, Taner Zi̇ylan, Khalil Awadh Murshed
Turkish Journal of Medical Sciences
Fetal femur length assessment has been the subject of numerous investigations. Skeletal growth disturbances, estimation of fetal gestational age, developmental abnormality and detection of certain fetal congenital anomalies, and determination of population growth characteristics have been the objectives of different investigators' studies. The purpose of this study was to evaluate the relationships between the crown-rump length (CRL) and fetal femur growth parameters and the gestational age during the second and third trimesters. Thirty dead normal immature and premature fetuses were selected from the fetal collection at the Anatomy Department of the Medical School, Selçuk University. Depending on the fetal CRL …
Anti-Hev Antibody Prevalence In Three Distinct Regions Of Turkey And Its Relationship With Age, Gender, Education And Abortions, Di̇lek Olcay, Can Polat Eyi̇gün, Şükrü Volkan Özgüven, İsmai̇l Yaşar Avci, Ahmet Bülent Beşi̇rbelli̇oğlu, Selma Yegane Tosun, Alaaddi̇n Pahsa
Anti-Hev Antibody Prevalence In Three Distinct Regions Of Turkey And Its Relationship With Age, Gender, Education And Abortions, Di̇lek Olcay, Can Polat Eyi̇gün, Şükrü Volkan Özgüven, İsmai̇l Yaşar Avci, Ahmet Bülent Beşi̇rbelli̇oğlu, Selma Yegane Tosun, Alaaddi̇n Pahsa
Turkish Journal of Medical Sciences
Hepatitis E virus (HEV) causes epidemics in developing countries such as India, Burma, Indonesia, Chad and China, but it causes sporadic cases in developed countries such as the U.S.A., Canada and the U.K. Turkey represents a bridge between HEV endemic and non-endemic areas, and HEV may cause epidemics in Turkey. In this study, the prevalence of HEV in three distinct regions of Turkey and its relationship with age, gender, education and abortions was investigated. Nine hundred ten randomly selected cases from three cities in three geographic regions of Turkey (Manisa from the Aegean region, Elmadağ/Ankara from Central Anatolia and Diyarbakır …
Suicide In The Province Of Eskişehir, Turkey: The Approach Of Forensic Medicine, Yasemi̇n Günay Balci, Emre Albek
Suicide In The Province Of Eskişehir, Turkey: The Approach Of Forensic Medicine, Yasemi̇n Günay Balci, Emre Albek
Turkish Journal of Medical Sciences
In the present study, a retrospective evaluation of suicides in the province of Eskişehir in 1997-1999 is made. Investigation reports of the Central Prosecutor's Office were obtained and the demographic data of the victims as well as the judicial criteria for the classification as "suicide" were evaluated. There were 94 cases of suicide and 65 of them (69.1%) involved males. Age distribution showed a predominance in the age group of 15-34 years. Suicide in males over 55 years of age occurred more frequently than in females (p < 0.05). Causes of death in suicides included hanging in 68.0% of cases, firearm wounding in 16.0%, jumping from heights in 7.4%, drug intake in 5.3%, railway suicides in 2.2% and butane inhalation in 1.1%; 79.8% of suicides occurred in residences. In 93.6% of the cases, scene investigation reports and drawings were obtainable, while photographs of the scene or of the victim were present in 53.2% of cases. A forensic medicine specialist's inquest had been performed in all cases whilst a medico-legal autopsy had been carried out in only 29.8% of cases. Death certificates were issued following an inquest and scene investigation in 66 cases. Medico-legal autopsies were performed in 73.3% of the cases of firearm wounding, 25.0% of the cases of hanging and 6.7% of suicides committed by other means. In conclusion, we emphasize the importance of a medico-legal autopsy in all suicide cases.
Abdominal Actinomycosis Appearing As An Intraabdominal Tumoral Mass, Ömer Şakrak, İpek Müderri̇soğlu, Abdulkadi̇r Bedi̇rli̇, Özhan İnce, Özlem Canöz
Abdominal Actinomycosis Appearing As An Intraabdominal Tumoral Mass, Ömer Şakrak, İpek Müderri̇soğlu, Abdulkadi̇r Bedi̇rli̇, Özhan İnce, Özlem Canöz
Turkish Journal of Medical Sciences
RAK^1 İpek MÜDERRİSOĞLU^2 Abdulkadir BEDİRLİ^1 Özhan İNCE^1 Özlem CANÖZ^3 Departments of ^1General Surgery, ^2Obstetrics and Gynecology, ^3Pathology, Faculty of Medicine, Erciyes University, Kayseri - Turkey
A Cerebral Hydatid Cyst Case First Presenting With Gerstmann's Syndrome: A Case Report And Literature Review, Mehmet Dumlu Aydin, Nazan Aydin
A Cerebral Hydatid Cyst Case First Presenting With Gerstmann's Syndrome: A Case Report And Literature Review, Mehmet Dumlu Aydin, Nazan Aydin
Turkish Journal of Medical Sciences
umlu AYDIN^1 Nazan AYDIN^2 Departments of ^1Neurosurgery , ^2Psychiatry, Faculty of Medicine, Atatürk University, Erzurum - Turkey
A Modified Method For The Determination Of Plasma Total Homocysteine By High Performance Liquid Chromatography, Serhat Tokgöz, Cumhur Bi̇lgi̇, Erdi̇nç Çakir, M. Kemal Erbi̇l, Türker Kutluay
A Modified Method For The Determination Of Plasma Total Homocysteine By High Performance Liquid Chromatography, Serhat Tokgöz, Cumhur Bi̇lgi̇, Erdi̇nç Çakir, M. Kemal Erbi̇l, Türker Kutluay
Turkish Journal of Medical Sciences
We have modified a high-performance liquid chromatography (HPLC) procedure for homocysteine assay using 7-fluoro-2, 1, 3-benzoxadiazole-4-sulfonamide (ABD-F) pre-column derivatization. In this study, the thiol compounds were liberated from plasma proteins by reduction with 2-mercaptoethanol (BME) and derivatized with a thiol-specific fluoregenic marker, ABD-F. The derivatives were separated by reversed-phase HPLC on a Hypersil C 18 column (4.6 x 150 mm; 5 µ) using isocratic elution with 0.1 M phosphate buffer pH 6.0 containing 8% methanol and fluorescence detection. Excitation and emission wavelengths were 386 and 516 nm. The peak of homocysteine was eluted at 413 ± 25 s. Mean within-day …
Paratesticular Solitary Fibrous Tumour: Case Report And Review Of The Literature, Nusret Akpolat, Arslan Ardiçoğlu, Seyfetti̇n Yahşi̇, A.Rahmi̇ Onur
Paratesticular Solitary Fibrous Tumour: Case Report And Review Of The Literature, Nusret Akpolat, Arslan Ardiçoğlu, Seyfetti̇n Yahşi̇, A.Rahmi̇ Onur
Turkish Journal of Medical Sciences
KPOLAT^1 Arslan ARDIÇOĞLU^2 Seyfettin YAHŞİ^1 A. Rahmi ONUR^2 Departments of ^1Pathology and ^2Urology, Faculty of Medicine, Fırat University, Elazığ - TURKEY