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Articles 391 - 420 of 4871
Full-Text Articles in Medicine and Health Sciences
Reliability And Validity Of New Isokinetic Strength Assessment For Rotator Cuff Muscles In A Muscle Architecture-Based Position, Çağlar Soylu, Mustafa Ertuğrul Yaşa, Pervin Demi̇r, Ahmet Mustafa Ada, Tüzün Firat, Necmiye Ün Yildirim
Reliability And Validity Of New Isokinetic Strength Assessment For Rotator Cuff Muscles In A Muscle Architecture-Based Position, Çağlar Soylu, Mustafa Ertuğrul Yaşa, Pervin Demi̇r, Ahmet Mustafa Ada, Tüzün Firat, Necmiye Ün Yildirim
Turkish Journal of Medical Sciences
Isokinetic strength assessment of the rotator cuff muscle is frequently applied in a variety of shoulder postures, butnone of these consider muscular architecture, which is one of the most important aspects of improving strength development. This studyaimed to examine the test and retest reliability and validity of the muscle architecture-based position (MABP), which is 25° abductionand 20° external rotation, in healthy subjects to be able to select a better isokinetic assessment position for shoulder rotator cuff muscles.Materials and methods: A total of 54 healthy males with a mean age of 21.0 ± 1.2 years and mean body mass index of …
The Effect Of Video-Assisted Training On Upper Extremity Problems And Functions After Rotator Cuff Repair: A Randomized Controlled Trial, Canan Kanat, Gülay Altun Uğraş, Recep Ünal, Servet Can Dönmez, Bahar Taşdelen, Fehmi Volkan Öztuna
The Effect Of Video-Assisted Training On Upper Extremity Problems And Functions After Rotator Cuff Repair: A Randomized Controlled Trial, Canan Kanat, Gülay Altun Uğraş, Recep Ünal, Servet Can Dönmez, Bahar Taşdelen, Fehmi Volkan Öztuna
Turkish Journal of Medical Sciences
The shoulder is the most mobile joint in the body, and is frequently exposed to injuries. The applied surgical treatments, protection of the shoulder after surgery, care in the use of the shoulder in activities of daily living (ADLs) and gradual exercise programs are all vital to the recovery process. The present study investigates the effect of video-assisted training (VAT) on upper extremity complications and functions after rotator cuff repair (RCR).Materials and method: Included in this prospective, parallel two-armed, randomized controlled study were an experimental group (n: 24) that received VAT detailing early postoperative care for RCR and instructions on …
Urologists’ Opinion On Treating Asymptomatic Stones: Would We Treat Ourselves As We Treat Our Patients? Survey From European Association Of Urology, Young Academicurologists, Endourology And Urolithiasis Working Party, Tarık Emre Şener, Thomas Tailly, Yılören Tanidir, Etienne Xavier Keller, Amelia Pietropaolo, Juan Gomez Rivas, Zeeshan Hameed, Vincent De Coninck, Tzevat Tefi̇k, Kemal Sarica, Ali Serdar Gözen, Andreas Skolarikos, Olivier Traxer, Christian Seitz, Bhaskar Somani
Urologists’ Opinion On Treating Asymptomatic Stones: Would We Treat Ourselves As We Treat Our Patients? Survey From European Association Of Urology, Young Academicurologists, Endourology And Urolithiasis Working Party, Tarık Emre Şener, Thomas Tailly, Yılören Tanidir, Etienne Xavier Keller, Amelia Pietropaolo, Juan Gomez Rivas, Zeeshan Hameed, Vincent De Coninck, Tzevat Tefi̇k, Kemal Sarica, Ali Serdar Gözen, Andreas Skolarikos, Olivier Traxer, Christian Seitz, Bhaskar Somani
Turkish Journal of Medical Sciences
Management of asymptomatic kidney stones is an ongoing debate with follow-up and treatment guidelines based on low-level evidence. Our aim was to evaluate current management of asymptomatic urinary stones.Materials and methods: A 70-question survey was designed in collaboration with European Association of Urology, Young Academic Urologists, Section of Uro-Technology and Section of Urolithiasis groups and distributed. Responders filled out hypothetical scenarios from 2 perspectives, either as treating physicians, or as patients themselves.Results: A total of 212 (40.01%) responses were obtained. Median responder age was 39 years. 75% of responders were interested in “urolithiasis”. 82.5% had never experienced a renal colic, …
Diurnal Rhythm Of Urinary Aquaporin-2 In Children With Primary Monosymptomatic Nocturnal Enuresis, Nehal Abdelhamid, Mohamed A. Abd Almawla, Aliaa A. Wahby, Mervat Ismail, Hani Abdelsalam Elmikaty, Hanan M. Hamed, Ingy Ashmawy, Bataul Mohamed Abdelraoaf, Enas Mokhtar Abdelhamid, Hassan M. Salam
Diurnal Rhythm Of Urinary Aquaporin-2 In Children With Primary Monosymptomatic Nocturnal Enuresis, Nehal Abdelhamid, Mohamed A. Abd Almawla, Aliaa A. Wahby, Mervat Ismail, Hani Abdelsalam Elmikaty, Hanan M. Hamed, Ingy Ashmawy, Bataul Mohamed Abdelraoaf, Enas Mokhtar Abdelhamid, Hassan M. Salam
Turkish Journal of Medical Sciences
Nocturnal enuresis can be frustrating for children and their families as the child ages. Our aim is to evaluate urine aquaporin 2 (AQP-2) as a noninvasive biomarker of water balance in children with primary monosymptomatic nocturnal enuresis (PMNE).Material and methods: The study included 90 children; sixty-eight children suffering from PMNE aged (9.57 ± 2.16) years and 22 healthy children with good toilet control, matched sex and age. All enuretic children were subjected to complete history taking, clinical evaluation, and bed wetting diary. Serum arginine vasopressin (AVP) and urine AQP-2 were tested in the morning (at 9–11 am) and evening (at …
Evaluation Of The Aquaporin Molecules Characterization In The Sperm Cells Of Men From Different Aged, Fikret Gevrek, Osman Serden Gencel, Selim Görgün, Mikail Kara, Muzaffer Katar
Evaluation Of The Aquaporin Molecules Characterization In The Sperm Cells Of Men From Different Aged, Fikret Gevrek, Osman Serden Gencel, Selim Görgün, Mikail Kara, Muzaffer Katar
Turkish Journal of Medical Sciences
Male infertility rises for many reasons, along with age; therefore, we aimed to research the characterization of aquaporin-3, 7, and 8 in human sperm belonging to different age groups. Material and methods: This study was conducted on sperm samples of men aged over 18 years. A total of 60 men were included in the study and divided into three age groups: group 1, age 18–25 years (n = 20); group 2, age 26–35 years (n = 20); and group 3, age ≥35 years (n = 20). Sperm ejaculates obtained from each participant were used for spermiogram tests, Kruger strict morphology …
Comparison Of The Clinical Efficacy Of Ultrasound-Guided Gon Blockade Using Low And High Concentrations Of Bupivacaine In Chronic Migraine, Ümit Murat Parpucu, Onur Küçük, Fatih Sağ, Suna Akın Takmaz, Barış Kiran, İsmail Eren Durmuş, Yılmaz Karaduman, Semih Aydemi̇r
Comparison Of The Clinical Efficacy Of Ultrasound-Guided Gon Blockade Using Low And High Concentrations Of Bupivacaine In Chronic Migraine, Ümit Murat Parpucu, Onur Küçük, Fatih Sağ, Suna Akın Takmaz, Barış Kiran, İsmail Eren Durmuş, Yılmaz Karaduman, Semih Aydemi̇r
Turkish Journal of Medical Sciences
In this study, it was aimed to retrospectively compare the effect of greater occipital nerve (GON) block performed with ultrasonography using low (0.3%) and high (0.5%) concentrations of bupivacaine on pain scores and patient satisfaction in chronic migraine (CM).Materials and methods: The mean number of days with pain, the mean duration of pain in the attacks, and the highest numerical rating scale (NRS) scores recorded in the 1 month preblock and 1 and 3 months postblock of 80 patients (40 for Group 1, 0.3% bupivacaine; 40 for Group 2, 0.5% bupivacaine) who underwent ultrasonography-guided GON block were recorded from the …
Sodium-Fluorescein-Guided Awake Surgery For Cerebral Metastases Located In Eloquent Brain Areas: Technical Notes And Preliminary Experiences, Alper Türkkan, Pınar Ocak, Marzieh Karimi Khezri, Ahmet Bekar
Sodium-Fluorescein-Guided Awake Surgery For Cerebral Metastases Located In Eloquent Brain Areas: Technical Notes And Preliminary Experiences, Alper Türkkan, Pınar Ocak, Marzieh Karimi Khezri, Ahmet Bekar
Turkish Journal of Medical Sciences
Awake craniotomy (AC) maximizes the resection of lesions in eloquent brain areas while preserving functionality.Tumor delineation with intraoperative use of sodium fluorescein (NaFl) facilitates total resection. When used with AC, it may allowfor safe resection without increasing the risk of postoperative neurologic deficits. This study investigated the efficacy and safety of thecombined use of NaFl and AC for maximum safe resection in patients with brain metastases.Material and methods: Patients who underwent AC due to brain metastasis in the Department of Neurosurgery of Uludağ University’sFaculty of Medicine between January 1, 2018 and August 1, 2022, were retrospectively analyzed. The study comprised …
Analysis Of Risk Factors And Changes In Myocardial Biomarker Levels In 122 Cases Of Early Neonatal Anemia, Zhenhua Sui
Analysis Of Risk Factors And Changes In Myocardial Biomarker Levels In 122 Cases Of Early Neonatal Anemia, Zhenhua Sui
Turkish Journal of Medical Sciences
Anemia in the first week after birth, which could affect growth, development, and organ function, should be an important warning sign to clinicians. The aim of this study was to assess the related risk factors of early neonatal anemia and to analyze the effect of anemia on the expression levels of myocardial markers in newborns.Materials and methods: Clinical data from 122 confirmed cases of anemic newborns and 108 nonanemic newborns were collected to analyze the independent risk factors for early anemia using logistic regression analyses. Blood samples were collected from both groups for the detection of myocardial markers, including the …
Risk Factors Of Congenital Nomalies Of The Kidney And Urinary Tract (Cakut): Exposureto Mobile Phones During Pregnancy, Kübra Çeleğen, Esra Özgül, Zeynep Yeşi̇ldağ, Erdem Yusuf Çamirci, Mehmet Çeleğen, Ayşegül Bükülmez
Risk Factors Of Congenital Nomalies Of The Kidney And Urinary Tract (Cakut): Exposureto Mobile Phones During Pregnancy, Kübra Çeleğen, Esra Özgül, Zeynep Yeşi̇ldağ, Erdem Yusuf Çamirci, Mehmet Çeleğen, Ayşegül Bükülmez
Turkish Journal of Medical Sciences
Congenital anomalies of the kidney and urinary tract(CAKUT) are the leading causes of childhood chronic kidney disease (CKD). The etiology of most of the cases is thought to be multifactorial. In this study, risk factors for CAKUT and the effect of mobile phone-related electromagnetic field (EMF) exposure during pregnancy were investigated.Materials and methods: Fifty-seven cases and 57 healthy controls under 2 years of age were included and their mothers were subjected to a questionnaire. Groups were compared for parents’ demographics, pregestational (chronic disease, body mass index, use of the folic acid supplements) and antenatal variables (gestational disease, weight gain during …
Predictive Values Of Mallampati Score, Tonsillar Size, And Bmi Z-Score In The Presence And Severity Of Obstructive Sleep Apnea In Pediatric Population, Ayşe Kaçar Bayram, Ahu Paketçi̇, Melek Nur Şahbaz, Sevde Daşdelen, Serkan Bilge Koca
Predictive Values Of Mallampati Score, Tonsillar Size, And Bmi Z-Score In The Presence And Severity Of Obstructive Sleep Apnea In Pediatric Population, Ayşe Kaçar Bayram, Ahu Paketçi̇, Melek Nur Şahbaz, Sevde Daşdelen, Serkan Bilge Koca
Turkish Journal of Medical Sciences
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder in children. Determination of riskfactors for the development of OSA is essential for early diagnosis and treatment of the disease and decreases the risk of negativeconsequences. This study aimed to investigate the predictive values of Mallampati score, tonsillar size, and BMI z-score in the presenceand severity of OSA in children.Materials and methods: This prospective cross-sectional study included 114 children with OSA symptoms. All children were assessedby BMI z-score, Mallampati score, and tonsillar size and underwent overnight polysomnography. They were consecutively selected andassigned to 4 groups as follows: Group 1 included …
Elderly And Aged Asthma Have Different Characteristics: Results Of A Multicenter Study, Ebru Damadoğlu, Özge Öztürk Aktaş, Bilun Gemi̇ci̇oğlu, Nafiye Yilmaz, Fulşen Bozkuş, Vehbi Ayhan, Ayşe Füsun Kalpaklioğlu, Ferda Öner Erkekol, Yavuz Havlucu, Fuat Erel, Ömür Aydin, Aydanur Eki̇ci̇, Ayşe Baççioğlu, Serap Argun Bariş, Gözde Köycü Buhari̇, Berrin Ceyhan, Özlem Göksel, Mehmet Köse, Adile Berna Dursun, Füsun Yildiz, Arzu Yorgancioğlu, Sacide Rana Işik, Dane Edi̇ger, İpek Kıvılcım Oğuzülgen, Ahmet Uğur Demi̇r, Gül Karakaya, Ali Fuat Kalyoncu
Elderly And Aged Asthma Have Different Characteristics: Results Of A Multicenter Study, Ebru Damadoğlu, Özge Öztürk Aktaş, Bilun Gemi̇ci̇oğlu, Nafiye Yilmaz, Fulşen Bozkuş, Vehbi Ayhan, Ayşe Füsun Kalpaklioğlu, Ferda Öner Erkekol, Yavuz Havlucu, Fuat Erel, Ömür Aydin, Aydanur Eki̇ci̇, Ayşe Baççioğlu, Serap Argun Bariş, Gözde Köycü Buhari̇, Berrin Ceyhan, Özlem Göksel, Mehmet Köse, Adile Berna Dursun, Füsun Yildiz, Arzu Yorgancioğlu, Sacide Rana Işik, Dane Edi̇ger, İpek Kıvılcım Oğuzülgen, Ahmet Uğur Demi̇r, Gül Karakaya, Ali Fuat Kalyoncu
Turkish Journal of Medical Sciences
Characteristics of asthma in the elderly population is not well-known. The aim of the present study was to evaluateasthma in the elderly population, to compare disease characteristics between patients diagnosed <60 (aged asthma) and ≥60 (elderlyasthma) years of age.Materials and methods: The study was a prospective, multicenter, cross-sectional type. A questionnaire was filled out to patients 60years of age and over, that have been followed for asthma for at least 3 months. Asthma Control Test (ACT), eight-item MoriskyMedication Adherence Scale (MMAS-8) was filled out, inhaler device technique was assessed.Results: A total of 399 patients were included from 17 tertiary care centers across the country. Mean age was 67.11 years and 331 (83%)were female. The age at asthma diagnosis was ≥60 in 146 (36.6%) patients. Patients diagnosed ≥60 years were older (p < 0.001), hadhigher education level (p < 0.001), more commonly had first-degree relative with asthma (p = 0.038), asthma related comorbidities(p = 0.009) and accompanying rhinitis/rhinosinusitis (p = 0.005), had better asthma control (p = 0.001), were using less controllermedications (p = 0.014). Inhaler technique was correct in 37% of the patients with no difference in between the groups. Treatmentcompliance was better in elderly asthma patients (p < 0.001). In the multivariate logistic regression analysis, having well-controlledasthma (odds ratio = 1.61, CI = 1.04–2.51), and high medication adherence rate (odds ratio = 2.43, CI = 1.48–4.0) were associated withbeing in the elderly asthma group.Conclusion: The characteristics of asthma are different among patients aged 60 years and over which seems to be related to onset age ofasthma. In our cohort, the elderly asthma patients had higher education level, and treatment adherence and asthma control was better.Patients diagnosed ≥60 years of age did not have more severe disease.
Evaluation Of Bone Health In Terms Of Osteoporosis In Adult Patients With Neuromuscular Disease, Özgür Zeliha Karaahmet, Eda Gürçay, Yasemin Tombak Yildizkan, Damla Cankurtaran, Zeynep Tuba Bahti̇yarca, Ebru Umay
Evaluation Of Bone Health In Terms Of Osteoporosis In Adult Patients With Neuromuscular Disease, Özgür Zeliha Karaahmet, Eda Gürçay, Yasemin Tombak Yildizkan, Damla Cankurtaran, Zeynep Tuba Bahti̇yarca, Ebru Umay
Turkish Journal of Medical Sciences
There are no current guidelines to help clinicians decide whether patients with adult neuromuscular disease (NMD) should be screened or treated for osteoporosis (OP). This study was undertaken to investigate the presence of OP in patients with various types of NMD and to examine the relationship between OP evaluation parameters and functional status, daily living activities, balance, and ambulation levels.Materials and methods: This cross-sectional study included 45 patients with NMDs. The patients were divided into 3 groups, depending on the affected component of the motor unit (neuronopathy group, neuropathy group, and myopathy group). The laboratory and demographic data were recorded …
Minipuberty Period Of Children With Atopic Dermatitis Compared To Healthy Children, Serkan Bilge Koca, Hatice Eke Güngör, Murat Cansever
Minipuberty Period Of Children With Atopic Dermatitis Compared To Healthy Children, Serkan Bilge Koca, Hatice Eke Güngör, Murat Cansever
Turkish Journal of Medical Sciences
Atopic dermatitis (AD) is an inflammatory, pruritic, noncontagious, chronic relapsing skin disease. Skin barrierabnormalities, excessive T helper 2 activity, and immune dysregulation are held responsible. Androgens have a negative effect on theintegrity of the epidermal skin barrier, while estrogen has a positive effect. We aimed to investigate whether hormones make a differencebetween healthy children and children with AD during minipuberty.Materials and methods: A total of 96 infants (postnatal 4–13 weeks), 48 diagnosed with AD and 48 controls, were included. Each groupconsisted of 23 girls (47.9%) and 25 boys (52.1%). Anthropometric examinations and hormone measurements were compared.Results: The two groups, having …
Psychometric Properties Of T E Canadian Occupational Performance Measure In Older Individuals, Onur Altuntaş, Medine Nur Özata Değerli̇, Ege Temi̇zkan, Gamze Eki̇ci̇
Psychometric Properties Of T E Canadian Occupational Performance Measure In Older Individuals, Onur Altuntaş, Medine Nur Özata Değerli̇, Ege Temi̇zkan, Gamze Eki̇ci̇
Turkish Journal of Medical Sciences
The Canadian Occupational Performance Measure (COPM) is a person-centered assessment tool frequently used to identify occupational problems in older individuals and establish goals for geriatric rehabilitation. This study aims to assess the validity and reliability of the Turkish version of COPM (COPM-TR) in older people.Materials and methods: One hundred older people completed the COPM-TR, and 25 of them participated in a retest within two weeks. The convergent construct validity analyses of the COPM-TR included conducting correlation analyses between the COPM-TR and the Functional Independence Measure (FIM) and Lawton Brody Instrumental Activities of Daily Living (Lawton-IADL) scales. The Performance and Satisfaction …
Is Gut Microbiota Of Patients With Als Different From That Of Healthy Individuals?, Zeri̇n Özaydin Aksun, Seyda Erdoğan, Ayşe Kalkanci, Eli̇f Ayça Şahi̇n, Tuğba Çuhadar, H. Özden Şener
Is Gut Microbiota Of Patients With Als Different From That Of Healthy Individuals?, Zeri̇n Özaydin Aksun, Seyda Erdoğan, Ayşe Kalkanci, Eli̇f Ayça Şahi̇n, Tuğba Çuhadar, H. Özden Şener
Turkish Journal of Medical Sciences
Background/aim: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Several studies shown that alterations of microbiota, increase the risk of neurodegenerative disorders. We aimed to reveal whether there is a difference in the gut microbiota of patients with ALS.Materials and methods: The participants are divided into three groups. Group 1 formed patients with ALS. Healthy family members living in the same house of the patients formed Group 2. Lastly, sex, age-matched healthy people were included in Group 3. Fecal samples were collected in 15 mL falcon tubes and stored at -80 °C. Genomic DNA isolation was performed on samples. …
Association Of Gait Speed And Handgrip Strength With Falls In Older Adults: The Role Of Cognition, Nesli̇han Kayahan Satiş, Sultan Keski̇n Demi̇rcan, Mehmet İlki̇n Naharci
Association Of Gait Speed And Handgrip Strength With Falls In Older Adults: The Role Of Cognition, Nesli̇han Kayahan Satiş, Sultan Keski̇n Demi̇rcan, Mehmet İlki̇n Naharci
Turkish Journal of Medical Sciences
Background/aim: Fall risk assessment is crucial for older adults because falls are associated with morbidity and mortality. This study investigated the relationship of gait speed (GS) and handgrip strength (HGS) with falls and assessed whether cognition mediates this causality.Materials and methods: The study was conducted in a tertiary referral geriatric outpatient clinic. The physical performance of participants was evaluated by GS and HGS. All falls the previous year were noted and factors associated with falls were analyzed using multivariate regression analysis.Results: A total of 1,018 older adults, with a mean age of 78.8 years (±7.2), of whom 64.2% were female, …
Distribution And Classifications Of Pkhd1 Gene Variants In Turkish Population With Next Generation Sequencing Method, Yüksel Gezgi̇n, Berkay Kirnaz, Rauf Baylarov, Afi̇g Berdeli̇
Distribution And Classifications Of Pkhd1 Gene Variants In Turkish Population With Next Generation Sequencing Method, Yüksel Gezgi̇n, Berkay Kirnaz, Rauf Baylarov, Afi̇g Berdeli̇
Turkish Journal of Medical Sciences
Background/aim: Autosomal recessive polycystic kidney disease is an inherited kidney disease. This study aims to detect rare and common DNA variants of the PKHD1 gene using next-generation sequencing (NGS) and to classify them in terms of being pathogenic according to The American College of Medical Genetics and Genomics. Materials and methods: NGS analysis was performed on the DNA of 304 patients who were referred to Ege University Molecular Medicine Laboratory with suspected polycystic kidney disease. Results: As a result, a total of 82 different DNA variants, 16 of which were novel, were detected. The breakdown of the variants found is …
Are Serum Thrombomodulin And Interleukin-8 Levels Associated With Disease Severity And Mortality In Critically Ill Children With Respiratory Failure?, Di̇lan Akgün Ünlü, Hazal Ceren Tuğrul, Selen Ceren Çakmak, Gürkan Atay, Seher Erdoğan
Are Serum Thrombomodulin And Interleukin-8 Levels Associated With Disease Severity And Mortality In Critically Ill Children With Respiratory Failure?, Di̇lan Akgün Ünlü, Hazal Ceren Tuğrul, Selen Ceren Çakmak, Gürkan Atay, Seher Erdoğan
Turkish Journal of Medical Sciences
Background/aim: Thrombomodulin (TM) is found on endothelial cell surfaces and increases in response to endothelial injury of different organs. Interleukin (IL)-8 regulates pulmonary inflammation. TM and IL-8 are candidate biological markers of acute respiratory distress syndrome (ARDS). The aim of the present study was to compare TM and IL-8 levels in pediatric patients with and without ARDS who received respiratory support and to determine their relationships with prognosis.Materials and methods: This was a prospective observational study of 55 patients who received respiratory support in the pediatric intensive care unit. Eighteen patients without active infection were defined as the control group. …
Rehabilitation Therapy Versus Drug-Only Therapy In Patients With Multiple Sclerosis, Florin Mihai Marcu, Doriana Ciobanu, Ioan Cosmin Boca, Elena Sirbu, Paul Alexandru Deme, Nicolae Catalin Hreniuc, Dorina Ianc
Rehabilitation Therapy Versus Drug-Only Therapy In Patients With Multiple Sclerosis, Florin Mihai Marcu, Doriana Ciobanu, Ioan Cosmin Boca, Elena Sirbu, Paul Alexandru Deme, Nicolae Catalin Hreniuc, Dorina Ianc
Turkish Journal of Medical Sciences
The treatment for multiple sclerosis (MS) does not cure the disease, but it is intended to reduce the intensity, duration, and frequency of symptoms. Rehabilitation therapy (RT), including an individualized physical therapy program (PTP) and adapted occupational therapy (OT), has benefits in terms of aerobic capacity, muscle strength, coordination, and ability to perform activities of daily living (ADL). The primary objective of this study was to examine the efficacy of RT comprising PTP, OT, and drug treatment (DT) versus DT alone in patients with MS. Another objective was to highlight the importance of continuing the PT and OT at home, …
The Relationship Between Trunk Control, Spinal Posture, And Spinal Mobility In Patients With Multiple Sclerosis: A Cross-Sectional Study, Taşkın Özkan, Nezehat Özgül Ünlüer, Mustafa Ertuğrul Yaşa, Buse Korkmaz, Gönül Vural
The Relationship Between Trunk Control, Spinal Posture, And Spinal Mobility In Patients With Multiple Sclerosis: A Cross-Sectional Study, Taşkın Özkan, Nezehat Özgül Ünlüer, Mustafa Ertuğrul Yaşa, Buse Korkmaz, Gönül Vural
Turkish Journal of Medical Sciences
Trunk control, which plays a key role in balance and mobility, decreases in patients with multiple sclerosis (PwMS) and many parameters such as sensory, motor, and musculoskeletal systems affect trunk control. The aim of this study was to compare trunk control, spinal mobility, and spinal posture in PwMS with healthy controls and investigate the relationship between trunk control with spinal posture and spinal mobility in PwMS.Materials and methods: The study was completed with 38 PwMS and 38 healthy controls with matched age and sex. Trunk control was evaluated with the Trunk Impairment Scale (TIS). Spinal posture and mobility were evaluated …
The Right Ventricle Outflow Tract Systolic Function Could Predict The Severity Of The Cirrhosis, İbrahim Dönmez, Güray Can, Emrah Acar
The Right Ventricle Outflow Tract Systolic Function Could Predict The Severity Of The Cirrhosis, İbrahim Dönmez, Güray Can, Emrah Acar
Turkish Journal of Medical Sciences
The distinctive liver framework is converted into structurally abnormal nodules as a consequence of tissue fibrosis in cirrhosis. Cardiac dysfunction in cirrhosis was described, and the term “cirrhotic cardiomyopathy (CCM)” was coined to describe this syndrome. Recent research has shown that the contractile characteristics of the right ventricular outflow tract (RVOT) have a significant impact on right ventricular functions. The right ventricular outflow tract-systolic excursion is an important systolic function marker of RVOT (RVOT-SE). There has yet to be published research on RVOT function in cirrhotic patients. We looked at the relationship between cirrhosis severity and the RVOT-SE.Materials and methods: …
The Effect Of Parity, Breastfeeding History, And Duration On Clinical And Pathological Characteristics Of Breast Cancer Patients, Naziye Ak, Zeynep Tuz, Esra Aydin, Ferhat Ferhatoğlu, Murat Sari, Nail Paksoy, İzzet Doğan, Anıl Yildiz, Rian Di̇şçi̇, Pınar Mualla Sai̇p
The Effect Of Parity, Breastfeeding History, And Duration On Clinical And Pathological Characteristics Of Breast Cancer Patients, Naziye Ak, Zeynep Tuz, Esra Aydin, Ferhat Ferhatoğlu, Murat Sari, Nail Paksoy, İzzet Doğan, Anıl Yildiz, Rian Di̇şçi̇, Pınar Mualla Sai̇p
Turkish Journal of Medical Sciences
The study is aimed to determine the relationship between the delivery and breastfeeding history of the patients andthe clinicopathological properties of breast cancer.Materials and methods: A questionnaire was utilized for the study, which included the age of diagnosis, the number of children at thetime of diagnosis, the age of the children, and the breastfeeding period of each child.Results: The study included 828 patients. The median age at diagnosis was 47 years for parous women and 42 years for nonparouswomen (p < 0.001). The tumor size of the patients diagnosed within the breastfeeding period was significantly larger compared to theother patients. Estrogen and progesterone receptor positivity were lower in patients diagnosed during breastfeeding. Additionally, themean number of positive lymph nodes, dissected lymph nodes, and positive lymph node/dissected lymph node ratio in parous andbreastfed patients with a nonmetastatic disease were statistically significantly higher in multivariable analysis than those patients whowere nulliparous and have not breastfed.Conclusion: Breast cancer is seen at a later age in patients who are parous than those who have never given birth. Patients who areparous and have breastfed tend to present with a higher stage of the disease.
Dynamic Contrast-Enhanced Mammography And Breast Mri In The Diagnosis Of Breast Cancer And Detection Of Tumor Size, Muhammed Teki̇nhatun, Nuran Sabi̇r, Ergun Erdem, Sevda Yilmaz, Furkan Ufuk
Dynamic Contrast-Enhanced Mammography And Breast Mri In The Diagnosis Of Breast Cancer And Detection Of Tumor Size, Muhammed Teki̇nhatun, Nuran Sabi̇r, Ergun Erdem, Sevda Yilmaz, Furkan Ufuk
Turkish Journal of Medical Sciences
The aim of this study is to evaluate the performance of contrast-enhanced mammography (CEM) and dynamic breast MRI techniques for diagnosing breast lesions, assess the diagnostic accuracy of CEM’s using histopathological findings, and compare lesion size measurements obtained from both methods with pathological size.Materials and methods: This prospective study included 120 lesions, of which 70 were malignant, in 104 patients who underwent CEM and MRI within a week. Two radiologists independently evaluated the MR and CEM images in separate sessions, using the BI-RADS classification system. Additionally, the maximum sizes of lesion were measured. Diagnostic accuracy parameters and the receiver operating …
Adjunctive Use Of Laser Biostimulation With Nonsurgical Periodontal Therapy: A Split Mouth, Randomized, Case-Control Study In Diabetic And Nondiabetic Periodontitispatients, Funda Akansel, Umur Sakallioğlu, Müge Lütfi̇oğlu, Feyza Otan Özden, Adil Karadağ
Adjunctive Use Of Laser Biostimulation With Nonsurgical Periodontal Therapy: A Split Mouth, Randomized, Case-Control Study In Diabetic And Nondiabetic Periodontitispatients, Funda Akansel, Umur Sakallioğlu, Müge Lütfi̇oğlu, Feyza Otan Özden, Adil Karadağ
Turkish Journal of Medical Sciences
Laser biostimulation therapy (LBT) is suggested to have positive effects on periodontal healing. This study evaluatedLBT with nonsurgical periodontal therapy (NSPT) in diabetes mellitus (DM) and systemic health (SH) conditions.Materials and methods: Thirty periodontitis patients (15 with DM and 15 with SH) were included in the study, which had a split-mouthdesign, by applying LBT in the mouth of the same systemic condition. Thus, 4 study groups were formed, as 1) NSPT – DM: NSPT alonein DM, 2) NSPT + LBT – DM: NSPT + LBT application in DM, 3) NSPT – SH: NSPT alone in SH, and 4) NSPT + …
Medical And Advanced Heart Failure Therapies In Türkiye, Sanem Nalbantgi̇l, Emre Demi̇r, Ahmet Çeli̇k, İnci̇ Tuğçe Çöllüoğlu, Nai̇m Ata, Mehmet Bi̇rhan Yilmaz, Anil Şahi̇n, Di̇lek Ural, Mustafa Mahi̇r Ülgü, Emi̇ne Arzu Kanik, Lale Di̇nç Asarcikli, Yüksel Çavuşoğlu, Selda Murat, Şuayi̇p Bi̇ri̇nci̇
Medical And Advanced Heart Failure Therapies In Türkiye, Sanem Nalbantgi̇l, Emre Demi̇r, Ahmet Çeli̇k, İnci̇ Tuğçe Çöllüoğlu, Nai̇m Ata, Mehmet Bi̇rhan Yilmaz, Anil Şahi̇n, Di̇lek Ural, Mustafa Mahi̇r Ülgü, Emi̇ne Arzu Kanik, Lale Di̇nç Asarcikli, Yüksel Çavuşoğlu, Selda Murat, Şuayi̇p Bi̇ri̇nci̇
Turkish Journal of Medical Sciences
Background/aim: Effective management of heart failure involves evidence-based use of multiple medications and their combinations. Furthermore, dosage escalation of the recommended medications is advised. In cases of advanced heart failure, long-term mechanical assistance devices or heart transplantation surgery may be necessary. The socio-economic situation creates unequal chances for people to access these treatments.The study aimed to analyze and compare medical and advanced heart failure treatments recommended by guidelines across various regions in Türkiye.Materials and methods: About 85 million citizen medical treatment records were utilized between January 1, 2016, and December 31, 2022. Medical and heart replacement treatment opportunities used in …
Outcomes Of Patients With Heart Failure In Türkiye, Anil Şahi̇n, Mehmet Bi̇rhan Yilmaz, Ahmet Çeli̇k, Tuğçe Çöllüoğlu, Di̇lek Ural, Lale Di̇nç Asarcikli, Sanem Nalbantgi̇l, Emre Demi̇r, Yüksel Çavuşoğlu, Selda Murat, Emi̇ne Arzu Kanik, Nai̇m Ata, Mustafa Mahi̇r Ülgü, Şuayi̇p Bi̇ri̇nci̇
Outcomes Of Patients With Heart Failure In Türkiye, Anil Şahi̇n, Mehmet Bi̇rhan Yilmaz, Ahmet Çeli̇k, Tuğçe Çöllüoğlu, Di̇lek Ural, Lale Di̇nç Asarcikli, Sanem Nalbantgi̇l, Emre Demi̇r, Yüksel Çavuşoğlu, Selda Murat, Emi̇ne Arzu Kanik, Nai̇m Ata, Mustafa Mahi̇r Ülgü, Şuayi̇p Bi̇ri̇nci̇
Turkish Journal of Medical Sciences
Background/Aim: Despite Türkiye's younger population, there is an emerging trend of earlier diagnoses of chronic diseases, including heart failure (HF). This study aims to shed light on survival rates, potential influences of guideline-directed therapies, and gender-based differences necessitating personalized management in HF.Materials and Methods: We conducted a nationwide retrospective cohort analysis on 2,722,151 patients with HF using de-identified data from the Turkish Ministry of Health’s National Electronic Database. Out of the total, there were 2,701,099 adult patients with HF. Adult patients were divided into two groups based on their outcome: those who were deceased and those who survived, and then …
The Potential Mechanism Of Treating Ic/Bps With Hyperbaric Oxygen By Reducing Vascular Endothelial Growth Inhibitor And Hypoxia-Inducible Factor-1Α, Jing Zhang, Jiarui Kang, Liyang Wu
The Potential Mechanism Of Treating Ic/Bps With Hyperbaric Oxygen By Reducing Vascular Endothelial Growth Inhibitor And Hypoxia-Inducible Factor-1Α, Jing Zhang, Jiarui Kang, Liyang Wu
Turkish Journal of Medical Sciences
To investigate the roles of vascular endothelial growth inhibitor (VEGI) and hypoxia-inducible factor-1α (HIF-1α) in the treatment of refractory interstitial cystitis/bladder pain syndrome (IC/BPS) with hyperbaric oxygen (HBO).Materials and methods: A total of 38 patients were included. They were assessed before and 6 months after HBO treatment. Three- day voiding diaries were recorded, and O’leary-Sant scores, visual analog scale (VAS) scores, quality of life (QoL) scores, pelvic pain, and urgency/frequency (PUF) scores were evaluated. Bladder capacity was assessed by cystoscopy. Bladder mucosa was collected for Western blot, qRT-PCR, and immunofluorescence staining to compare the expression of VEGI and HIF-1α before …
Leaky Gut And Inflammatory Biomarkers In A Medication Overuse Headache Model In Male Rats, Doğa Vuralli, Hale Gök Dağidir, Elif Abbasoğlu Topa, Hayrunnisa Bolay Belen
Leaky Gut And Inflammatory Biomarkers In A Medication Overuse Headache Model In Male Rats, Doğa Vuralli, Hale Gök Dağidir, Elif Abbasoğlu Topa, Hayrunnisa Bolay Belen
Turkish Journal of Medical Sciences
Medication overuse is common among chronic migraine patients and nonsteroidal antiinflammatory drugs (NSAIDs)are the most frequently overused drugs. The pathophysiological mechanisms underlying medication overuse headache (MOH) are notcompletely understood. Intestinal hyperpermeability and leaky gut are reported in patients using NSAIDs. The aim of the study is toinvestigate the role of leaky gut and inflammation in an MOH model MOH model in male rats.Methods: The study was conducted in male Sprague Dawley rats. There were two experimental groups. The first group was the chronicNSAID group in which the rats received mefenamic acid (n = 8) for four weeks intraperitoneally (ip) and …
Clinical Characteristics And Disease Course Before And After Sars-Cov-2 Infection In A Large Cohort Of Systemic Sclerosis Patients, Aslıhan Avanoğlu Güler, Büşra Özçi̇men, Mesude Seda Aydoğdu, Alper Sari, Aliyeva Numune, Nazife Tüzün Ersan, Seda Çolak, Hazan Karadeni̇z, İbrahim Vasi̇, Hamit Küçük, Yasemin Yalçinkaya, Abdulsamet Erden, Mehmet Kayaalp, Mehmet Akif Öztürk, Berna Göker, Ahmet Omma, Sedat Yilmaz, Süleyman Serdar Koca, Murat İnanç, Ali Akdoğan, Abdurrahman Tufan
Clinical Characteristics And Disease Course Before And After Sars-Cov-2 Infection In A Large Cohort Of Systemic Sclerosis Patients, Aslıhan Avanoğlu Güler, Büşra Özçi̇men, Mesude Seda Aydoğdu, Alper Sari, Aliyeva Numune, Nazife Tüzün Ersan, Seda Çolak, Hazan Karadeni̇z, İbrahim Vasi̇, Hamit Küçük, Yasemin Yalçinkaya, Abdulsamet Erden, Mehmet Kayaalp, Mehmet Akif Öztürk, Berna Göker, Ahmet Omma, Sedat Yilmaz, Süleyman Serdar Koca, Murat İnanç, Ali Akdoğan, Abdurrahman Tufan
Turkish Journal of Medical Sciences
The objective of this study is to evaluate the clinical presentations and adverse outcomes of Coronavirus Disease 2019 (COVID-19) in patients with systemic sclerosis (SSc) and assess the impact of SSc features on the clinical course of COVID-19.Materials and methods: In this multicenter, retrospective study, SSc patients with COVID-19 were included. Clinical features of SSc, along with detailed COVID-19 data, were extracted from medical records and patient interviews.Results: The study included 112 patients (mean age 51.4 ± 12.8 years; 90.2% female). SSc-associated interstitial lung disease (ILD) was evident in 57.1% of the patients. The findings revealed hospitalization in 25.5%, respiratory …