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Articles 3751 - 3780 of 4871
Full-Text Articles in Medicine and Health Sciences
Measurement Of Total Antioxidant Response In Colorectal Cancer Using A Novel Automated Method, Abdullah Özgönül, Nurten Aksoy, Fuat Di̇lmec, Ali̇ Uzunköy, Şahi̇n Aksoy
Measurement Of Total Antioxidant Response In Colorectal Cancer Using A Novel Automated Method, Abdullah Özgönül, Nurten Aksoy, Fuat Di̇lmec, Ali̇ Uzunköy, Şahi̇n Aksoy
Turkish Journal of Medical Sciences
Aim: The aim of this study was to compare the antioxidative status in patients with colorectal cancer and healthy controls, based on measurements made using a novel method. Materials and Methods: The study was conducted between 2005 and 2007, and included 30 patients with colorectal cancer and 30 healthy controls. To determine the antioxidative status of the patients and healthy controls, serum total antioxidant capacity was measured using a novel automated method. Blood samples were taken from the healthy controls and the patients. Results: Total serum antioxidant capacity was significantly lower in colorectal cancer patients than in healthy persons (P < 0.023). Conclusions: Patients with colorectal cancer are exposed to oxidative stress, which may have a role in the pathogenesis of the disease. The novel automated method used in this study was developed in our laboratory, and is feasible and fully automated; therefore, it may be useful for evaluating oxidative-antioxidative balance in patients with colorectal cancer.
The Role Of Magnetic Resonance Imaging In The Prediction Of The Neurodevelopmental Outcome Of Acute Bilirubin Encephalopathy In Newborns, Mustafa Mansur Tatli, Ahmet Karadağ, Ender Ödemi̇ş, Sümeyye Sarraoğlu, Mehmet Yörübulut
The Role Of Magnetic Resonance Imaging In The Prediction Of The Neurodevelopmental Outcome Of Acute Bilirubin Encephalopathy In Newborns, Mustafa Mansur Tatli, Ahmet Karadağ, Ender Ödemi̇ş, Sümeyye Sarraoğlu, Mehmet Yörübulut
Turkish Journal of Medical Sciences
Aim: Magnetic resonance imaging (MRI) is widely used in the diagnosis of acute bilirubin encephalopathy, but the relationship between MRI findings and neurodevelopmental outcome in newborns with acute bilirubin encephalopathy remains unclear. The aim of this study was to investigate the relationship between acute bilirubin encephalopathy, MRI findings, and neurodevelopmental outcome. Materials and Methods: The study included 13 infants with acute bilirubin encephalopathy. MRI was performed at 11-30 days of age. Infants were evaluated using the Denver Developmental Screening Test at 3 and 6 months of age. Results: Four of the 13 infants developed well. Five infants had abnormal MRI …
The Effect Of Anterior Nasal Packing With Airway Tubes On Pulmonary Function Following Septoplasty*, Hani̇fi̇ Kurtaran, Nebi̇l Ark, Fati̇h Sadikoğlu, K. Şeri̇fe Uğur, Türker Yilmaz, Zeki̇ Yildirim, Davut Aktaş
The Effect Of Anterior Nasal Packing With Airway Tubes On Pulmonary Function Following Septoplasty*, Hani̇fi̇ Kurtaran, Nebi̇l Ark, Fati̇h Sadikoğlu, K. Şeri̇fe Uğur, Türker Yilmaz, Zeki̇ Yildirim, Davut Aktaş
Turkish Journal of Medical Sciences
Aim: To investigate the effects of nasal packing with airway tubes on pulmonary function following septoplasty. Materials and methods: Fifty patients who were operated for nasal septal deviation between 2006 and 2008 were included in our study. Nasal packs with airway tubes were used for all patients following septoplasty. Pulmonary function tests and PO2 measurements with pulse oximetry were performed preoperatively and in the second postoperative day just before removal of the nasal pack. Forced Vital Capacity (FVC), Forced Expiratory Volume in 1 Second (FEV_1), FEV_1/FVC (FEV_1%), Forced Expiratory Flow (FEF_{25-75}%), and PO2 values were compared. Results: The mean age …
Annexin A2, A7, And A11 Expression In Head And Neck Squamous Cell Carcinoma*, Sema Hücümenoğlu, Berrak Gümüşkaya, Murat Alper, Bülent Öcal, Erdem Karabulut
Annexin A2, A7, And A11 Expression In Head And Neck Squamous Cell Carcinoma*, Sema Hücümenoğlu, Berrak Gümüşkaya, Murat Alper, Bülent Öcal, Erdem Karabulut
Turkish Journal of Medical Sciences
Aim: To investigate annexin A2 (ANXA2), annexin A7 (ANXA7), and annexin A11 (ANXA11) expression in head and neck squamous cell carcinoma (HNSCC). Although overexpression of ANXA2 has been reported in HNSCC, there are no studies on ANXA7 or ANXA11 in the same region. Materials and Methods: ANXA2, ANXA7, and ANXA11 were immunohistochemically studied in paraffin-embedded sections obtained from 43 patients with HNSCC. Results: ANXA2 and ANXA11 expression was more intense in the tumor areas in HNSCC (P = 0 for ANXA2, P = 0.05 for ANXA11). Both the tumors and normal mucosae showed membranous staining for ANXA7 and ANXA2, while …
Radiological And Pathological Correlation In Patients With Bronchioloalveolar Lung Carcinoma, Serpi̇l Öcal, Gülnur Önde Üçoluk, Belgi̇n Samurkaşoğlu, Funda Demi̇rağ, İlker Eti̇kan, Peli̇n Bayazit
Radiological And Pathological Correlation In Patients With Bronchioloalveolar Lung Carcinoma, Serpi̇l Öcal, Gülnur Önde Üçoluk, Belgi̇n Samurkaşoğlu, Funda Demi̇rağ, İlker Eti̇kan, Peli̇n Bayazit
Turkish Journal of Medical Sciences
Aim: To assess the correlation between pathological and radiological findings in patients with pure bronchioloalveolar carcinoma (BAC). Materials and Methods: We retrospectively evaluated the pathological and radiological findings in patients with pure BAC. Results: We reviewed the case records, pathological specimens, and computer files of 26 patients with a pathologic diagnosis of pure BAC during a 3-year period. There was a statistically significant relationship between pathological and radiological findings (X^2 = 15.143, P = 0.004). There was a correlation between mucinous pathology and diffuse pattern, as well as between non-mucinous pathology and solitary nodule/mass/cavitation. A statistically significant relationship between lymphocytic …
Evaluation Of Lower Urinary System Symptoms And Neurogenic Bladder In Children With Cerebral Palsy: Relationships With The Severity Of Cerebral Palsy And Mental Status, Si̇bel Ünsal, Canan Çulha, Hakan Tunç, Murat Kurt, Sumru Özel, Ali̇ Atan
Evaluation Of Lower Urinary System Symptoms And Neurogenic Bladder In Children With Cerebral Palsy: Relationships With The Severity Of Cerebral Palsy And Mental Status, Si̇bel Ünsal, Canan Çulha, Hakan Tunç, Murat Kurt, Sumru Özel, Ali̇ Atan
Turkish Journal of Medical Sciences
Aim: This study aimed to evaluate lower urinary system symptoms, to determine bladder type in children with cerebral palsy (CP), and to determine the relationship between bladder type, and the severity of CP and mental status of the children. Materials and Methods: The study included 41 children with CP. Subjects were first asked to provide information concerning lower urinary system symptoms. Urodynamic examination was performed in 41 children with CP. The severity of CP was determined according to the Gross Motor Functional Classification System (GMFCS). The Stanford-Binet Intelligence Scale was used to determine intelligence quotients (IQ). After urodynamic examination, subjects …
Body Fat, Dyslipidemia, Blood Pressure And The Effects Of Smoking In Germans And Turks, Günay Can, Peter Schwandt, Altan Onat, Gülay Hergenç, Gerda-Maria Haas
Body Fat, Dyslipidemia, Blood Pressure And The Effects Of Smoking In Germans And Turks, Günay Can, Peter Schwandt, Altan Onat, Gülay Hergenç, Gerda-Maria Haas
Turkish Journal of Medical Sciences
Aim: Determining the difference regarding obesity in German and Turkish adults. Materials and Methods: This study examined a cross-section of adults aged 30-79 years old. Age-adjustment was uniformly provided for comparisons. Results: Among 3055 Germans and 2925 Turks, Turkish women had significantly higher markers of (abdominal) obesity than German women, while waist circumference (WC) was similar among males. Blood pressure (BP), concentrations of total, LDL-cholesterol, and apolipoprotein B were significantly higher among Germans, whereas Turks had markedly higher fasting triglycerides and lower HDL-cholesterol. Unlike Germans, the current trend of smoking among Turks correlates with lower WC and lower systolic BP …
Clinical Evaluation Of 625 Lacunar Syndrome Patients, Kavian Ghandehari, Zahra Izadi Mood
Clinical Evaluation Of 625 Lacunar Syndrome Patients, Kavian Ghandehari, Zahra Izadi Mood
Turkish Journal of Medical Sciences
Aim: Lacunar syndromes consist of a group of characteristic clinical presentations that are usually compatible with a small deep infarct. Validation of these syndromes could help neurologists predict the prognosis and type of cerebrovascular disease. Materials and Methods: Consecutive stroke patients on 2 Iranian stroke registries compiled between 2001 and 2007 were enrolled in this prospective validation study. Lacunar syndromes were defined as pure motor, pure sensory, mixed sensory motor, ataxic hemiparesis, dysarthria clumsy hand, and atypical subtypes. All of the patients with ischemic stroke had at least one brain CT scan performed 48 h after stroke. Patients whose CT …
Ureteroscopic Management Of Distal Ureteral Stones In Children: Holmium: Yag Laser Vs. Pneumatic Lithotripsy, Turgut Yapanoğlu, Hasan Riza Aydin, Yilmaz Aksoy, İsa Özbey
Ureteroscopic Management Of Distal Ureteral Stones In Children: Holmium: Yag Laser Vs. Pneumatic Lithotripsy, Turgut Yapanoğlu, Hasan Riza Aydin, Yilmaz Aksoy, İsa Özbey
Turkish Journal of Medical Sciences
Aim: In this retrospective study, we aimed to compare the treatment results of pneumatic and holmium laser-assisted ureteroscopy in managing distal ureteral calculi in children. Materials and methods: The study group included a total of 36 children (23 boys, 13 girls) who underwent ureteroscopy between June 1998 and April 2008 due to distal ureteral calculi. Pneumatic lithotripsy was performed in 11 children and holmium:YAG laser lithotripsy in 25. Results: Their ages ranged from 18 months to 14 years (mean: 8.5 ± 3.5 years). The overall success rate for the holmium:YAG laser lithotripsy (100%) was higher than that of pneumatic lithotripsy …
Increased P Wave Dispersion In Hypothyroidism: A Sign Of Risk Of Atrial Fibrillation, Ramazan Akdemi̇r, Nesli̇han Ebru Eryaşar, Kudret Çeli̇k, Aşkin Güngüneş, Hakan Ci̇nemre, Cemi̇l Bi̇li̇r, Nermi̇n Akdemi̇r, Harun Kiliç
Increased P Wave Dispersion In Hypothyroidism: A Sign Of Risk Of Atrial Fibrillation, Ramazan Akdemi̇r, Nesli̇han Ebru Eryaşar, Kudret Çeli̇k, Aşkin Güngüneş, Hakan Ci̇nemre, Cemi̇l Bi̇li̇r, Nermi̇n Akdemi̇r, Harun Kiliç
Turkish Journal of Medical Sciences
Aim: As in hyperthyroidism, cardiac arrhythmias can be seen in hypothyroidism. In this study, we measured P wave dispersion among hypothyroid patients to evaluate atrial fibrillation risk. Methods: 75 patients who received first time diagnosis of hypothyroidism and 40 normal control patients were included in this study. Each patient had echocardiographic and electrocardiographic studies were carried out. Groups were compared for statistically significant difference in P wave dispersion, minimum P wave duration and maximum P wave duration. Results: The groups were similar in echocardiographic and electrocardiograpic features. P wave dispersion was significantly higher in the hypothyroid group compared to normal …
Cefoperazone-Sulbactam Plus Amikacin Empirical Therapy For Febrile Neutropenia In Children With Cancer, İbrahi̇m Bayram, Fati̇h Erbey, Derya Alabaz, Sema Yilmaz, Ati̇la Tanyeli̇
Cefoperazone-Sulbactam Plus Amikacin Empirical Therapy For Febrile Neutropenia In Children With Cancer, İbrahi̇m Bayram, Fati̇h Erbey, Derya Alabaz, Sema Yilmaz, Ati̇la Tanyeli̇
Turkish Journal of Medical Sciences
Aim: To determine the efficacy and safety of cefoperazone-sulbactam combined with amikacin in the treatment of febrile neutropenia in children with cancer. Materials and Methods: The study included 20 cancer cases with 26 febrile neutropenia (FEN) episodes. Patient selection criteria were defined according to the guidelines issued by the Infectious Disease Society of America (IDSA). Results: Patients diagnosed with acute leukemia (58%) and solid tumors (42%) were recorded. Twelve (46.2%) of the primary disease cases were refractory. The number of infection episodes identified microbiologically and clinically was 10 (38.5%) and 12 (46.1%), respectively. Fever of unknown origin was observed in …
Cognitive Impairment Among Type-2 Diabetic Subjects And Its Relationship With Long-Term Complications, Oğuz Teki̇n, Serdar Çukur, Remzi̇ Karadağ, Ayşe Tunca, Olgun Göktaş, Adem Özkara, Bünyami̇n Işik, Sevsen Cebeci̇, Ramazan Yi̇ği̇toğlu
Cognitive Impairment Among Type-2 Diabetic Subjects And Its Relationship With Long-Term Complications, Oğuz Teki̇n, Serdar Çukur, Remzi̇ Karadağ, Ayşe Tunca, Olgun Göktaş, Adem Özkara, Bünyami̇n Işik, Sevsen Cebeci̇, Ramazan Yi̇ği̇toğlu
Turkish Journal of Medical Sciences
Aim: Studies about relationships between diabetes mellitus, diabetic complications, and cognitive functions have been initiative factors for this study. We evaluated various relations between procedure of the disease, diabetic complications, and cognitive functions among diabetic subjects. Materials and methods: Type-2 diabetic patients were evaluated for their disease status, complications, and cognitive functions (by Mini Mental State Examination (MMSE) test). We compared MMSE results of the patients with the control group. Results: We evaluated 75 patients with type-2 diabetes mellitus and 49 control subjects. Orientation (P = 0.006), attention and calculation (P = 0.002), and total (P < 0.001) scores of the control group were significantly greater compared to the diabetic group. We observed negative correlation between the length of disease and cognitive functions within the diabetic group. Recall scores of the diabetic subjects with 6 and less HBAIC levels were significantly greater than those with 6.1 and greater levels (P = 0.049). We observed negative relations between registration scores and retinopathy, but not between orientation and total scores and hypertension among diabetic subjects. Conclusion: Type-2 diabetes mellitus may destroy cognitive function. Length of disease, high serum HBAIC levels, hypertension, and retinopathy are significant additional risk factors. We conclude that cognitive function assessment should be routine procedure in the management of type-2 diabetes mellitus.
Cut-Off Value Of D-Dimer In Pulmonary Thromboembolism And Pneumonia, Ayşegül Karalezli̇, H. Canan Hasanoğlu, Selda Kaya, Eli̇f Babaoğlu, Z. Ci̇bali̇ Açikgöz, Asi̇ye Kanbay, Derya Öztuna
Cut-Off Value Of D-Dimer In Pulmonary Thromboembolism And Pneumonia, Ayşegül Karalezli̇, H. Canan Hasanoğlu, Selda Kaya, Eli̇f Babaoğlu, Z. Ci̇bali̇ Açikgöz, Asi̇ye Kanbay, Derya Öztuna
Turkish Journal of Medical Sciences
Aim: The differential diagnosis of pulmonary thromboembolism (PTE) and pneumonia remains difficult in emergency rooms. High D-dimer levels in the pneumonia may be misdiagnosed as PTE on the basis of similar clinical, radiological, and laboratory findings. Since D-dimer elevation may also be seen in pneumonia cases, the comparison of D-dimer values in patients diagnosed as pneumonia and PTE, in order to determine a cut-off value between the 2 diseases, was aimed in this study. Materials and methods: Patients in the community acquired pneumonia (CAP) group were classified according to the American Thoracic Society (ATS) 2001 criteria. Groups III and IV …
Does Employment Status Influence Obesity Prevalence Among Females? A Comparative Study From Ankara, Turkey, Di̇lek Aslan, Zeynep Altin, Necmi̇ye Beydağ, Celi̇le Hati̇poğlu
Does Employment Status Influence Obesity Prevalence Among Females? A Comparative Study From Ankara, Turkey, Di̇lek Aslan, Zeynep Altin, Necmi̇ye Beydağ, Celi̇le Hati̇poğlu
Turkish Journal of Medical Sciences
Aim: In this study, we aimed to compare the nutritional habits and obesity status of employed and not-employed (i.e. homemakers) women from an urban population in Ankara between April 2 and 17, 2007. Materials and methods: Employed females (107) were amongst Keçiören (a district of Ankara) municipal employees, and homemakers were selected among the residents of the catchment area of a primary health care unit (PHCU) within the same district. The 2 groups (employed and homemakers) were high school and university graduates and were similar to each other in terms of education and age. The World Health Organization defines "overweight" …
The Effect Of Experimentally Induced Carbon Dioxide Pneumoperitoneum On Intra-Abdominal And Intra-Esophageal Ph, Tutku Soyer, Tolga Reşat Aydos, Zuhal Aktuna, Oğuzhan Korkut, Gökhan Osmanoğlu, Öymen Hançerli̇oğullari, Murat Çakmak
The Effect Of Experimentally Induced Carbon Dioxide Pneumoperitoneum On Intra-Abdominal And Intra-Esophageal Ph, Tutku Soyer, Tolga Reşat Aydos, Zuhal Aktuna, Oğuzhan Korkut, Gökhan Osmanoğlu, Öymen Hançerli̇oğullari, Murat Çakmak
Turkish Journal of Medical Sciences
Aim: An experimental study was performed to evaluate the effect of CO_2 pneumoperitoneum on intra-abdominal (IA) and intra-esophageal (IE) pH. Material and methods: The study included 18 Wistar rats. In the control group (n = 6) a pH catheter was inserted into the peritoneal cavity via a left upper quadrant incision and another catheter was inserted into the lower esophagus via the oral route. Pre- and post-insufflation IA and IE pH were recorded every 5 min for 1 h. In the experimental groups, in addition to pH catheters, a 16-G catheter was inserted into the abdomen above the umbilicus. In …
Etofenamate And Anastomoses Of The Colon In Rats, Aydin İnan, Önder Sürgi̇t, Meral Şen, Ayhan Akpinar, Mi̇kdat Bozer
Etofenamate And Anastomoses Of The Colon In Rats, Aydin İnan, Önder Sürgi̇t, Meral Şen, Ayhan Akpinar, Mi̇kdat Bozer
Turkish Journal of Medical Sciences
Aim: Non-steroidal anti-inflammatory drugs have been used for many years due to their analgesic and anti-inflammatory properties. They have also been used for postoperative analgesia. We aimed to study the effects of etofenamate, a non-steroidal anti-inflammatory drug, on the healing of colonic anastomoses in rats. Materials and methods: Sprague-Dawley rats were used in this study. Resection and anastomosis were performed on the distal colon. The etofenamate group received 30 mg/kg etofenamate and the control group received 0.1 mL of 0.9% NaCl intramuscularly daily. Bursting pressures of anastomoses and hydroxyproline levels of perianastomotic tissues were determined on days 3 and 7. …
Clinical And Pathological Features Of Nodular Gastritis In Adults, İbrahi̇m Koral Önal, Cenk Sökmensüer, Eda Demi̇r Önal, Osman Ersoy, Özgür Yeni̇ova, Musa Aydinli, Özlem Yönem, Özgür Harmanci, Yusuf Bayraktar, Fi̇gen Batman
Clinical And Pathological Features Of Nodular Gastritis In Adults, İbrahi̇m Koral Önal, Cenk Sökmensüer, Eda Demi̇r Önal, Osman Ersoy, Özgür Yeni̇ova, Musa Aydinli, Özlem Yönem, Özgür Harmanci, Yusuf Bayraktar, Fi̇gen Batman
Turkish Journal of Medical Sciences
Aim: Data on antral nodularity in adults are sparse. Although the association of nodular gastritis with Helicobacter pylori infection is well known, its potential as a premalignant lesion and its association with other gastroduodenal diseases are questionable. Materials and methods: The medical records of the patients between 2003 and 2006 were retrospectively reviewed to analyze their demographics, clinical characteristics, and endoscopic and pathological features. Results: Of 9949 adult patients who underwent endoscopy, 185 (1.86%) were diagnosed with nodular gastritis, 167 (90%) of whom had dyspepsia. The presence of Helicobacter pylori was demonstrated in 65.4% (121/185). There were 16 cases (8.7%) …
An Analysis Of Adult Patients With Pulmonary And Extrapulmonary Tuberculosis*, Aygün Öztop, İpek Ünsal, Türkan Günay, Vi̇ldan Avkan Oğuz, Riza Çakmak
An Analysis Of Adult Patients With Pulmonary And Extrapulmonary Tuberculosis*, Aygün Öztop, İpek Ünsal, Türkan Günay, Vi̇ldan Avkan Oğuz, Riza Çakmak
Turkish Journal of Medical Sciences
Aim: In this study, it was planned to compare the features of pulmonary and extra-pulmonary tuberculosis patients over age 15 years. Materials and methods: We compared 360 newly diagnosed pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) patients who were treated and followed up in Kahramanlar Tuberculosis Dispensary between 2000 and 2003, and were older than 15 years of age. The medical records of both patient groups were investigated in terms of age, sex, accompanying diseases, contact history and means of diagnosis. Results: The data were compared statistically between the 2 groups. Of these patients 78.1% were diagnosed with PTB while …
The Effects Of Adding Tramadol To Ropivacaine On Axillary Brachial Plexus Blockade In Uremic Patients*, Bayazit Di̇kmen, Mehmet Gamli, Eyüp Horasanli, Di̇lşen Örnek, Melekşah Pekel, Aydin Selçuk
The Effects Of Adding Tramadol To Ropivacaine On Axillary Brachial Plexus Blockade In Uremic Patients*, Bayazit Di̇kmen, Mehmet Gamli, Eyüp Horasanli, Di̇lşen Örnek, Melekşah Pekel, Aydin Selçuk
Turkish Journal of Medical Sciences
Aim: To evaluate the effect of tramadol added to ropivacaine on quality of anesthesia, onset of sensory and motor blockade, duration of sensory and motor blockade, and first analgesic request time for axillary brachial plexus block in uremic patients. Materials and methods: After institutional approval and informed consent had been obtained, 45 ASA III uremic patients (age range 30-80) scheduled for arteriovenous fistula surgery were included in the study. Patients were randomly allocated into 2 groups. Axillary block was performed with a peripheral nerve stimulator by multiple injection technique. Patients in Group R (n = 23) received 38 mL of …
The Efficacy Of Quantitative Fluorescent-Polymerase Chain Reaction (Qf-Pcr) In The Diagnosis Of Prenatal Aneuploidy, Serpi̇l Aydoğmuş, Hüseyi̇n Levent Keski̇n, Semra Baykal Gökçe, Ayşe Fi̇li̇z Avşar, Emi̇ne Çelen
The Efficacy Of Quantitative Fluorescent-Polymerase Chain Reaction (Qf-Pcr) In The Diagnosis Of Prenatal Aneuploidy, Serpi̇l Aydoğmuş, Hüseyi̇n Levent Keski̇n, Semra Baykal Gökçe, Ayşe Fi̇li̇z Avşar, Emi̇ne Çelen
Turkish Journal of Medical Sciences
Aim: To investigate the efficacy of quantitative fluorescent-polymerase chain reaction (QF-PCR) in the diagnosis of aneuploidy. Materials and methods: The study included 40 pregnant women considered to be at high risk, based on positive trisomy 21 screening results, that underwent amniocentesis for karyotyping to detect chromosomal anomalies. In amniotic fluid aneuploidy detection was carried out by both standard karyotyping and the QF-PCR method, and the results obtained with both methods were compared. In order to determine the efficacy of QF-PCR, its sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated. Results: Of the 40 patients’ results …
Endoscopic Polypectomy: Outcomes Of 467 Cases In 20 Years, S. Selçuk Atamanalp, Fuat Şentürk, Nesri̇n Gürsan, Gürkan Öztürk, Abdul Meci̇t Kantarci, M. İlhan Yildirgan, Mahmut Başoğlu
Endoscopic Polypectomy: Outcomes Of 467 Cases In 20 Years, S. Selçuk Atamanalp, Fuat Şentürk, Nesri̇n Gürsan, Gürkan Öztürk, Abdul Meci̇t Kantarci, M. İlhan Yildirgan, Mahmut Başoğlu
Turkish Journal of Medical Sciences
Aim: Endoscopic polypectomy has an important place in the treatment of polyps—the preliminary lesions of colorectal cancers. This study aimed to discuss the outcomes of endoscopic polypectomy in 467 patients for 692 polyps over the course of 20 years. Materials and methods: The records of 692 endoscopic polypectomies performed in 467 patients between July 1988 and July 2008 were retrospectively evaluated. Results: Patient age ranged from 3 to 85 years (mean: 50.6 years), and 302 of the 467 (64.7%) patients were male. Polypectomy was performed for 692 polyps (mean: 1.5; range: 1-12). The most common polyp location was the rectum …
An Abnormal Digital Rectal Examination Is An Independent Predictor Of High Radical Prostatectomy Gleason’S Score ( ≥7) In Patients With Clinically Localized Prostate Cancer, Özgür Uğurlu, Mesut Çeti̇nkaya, Cüneyt Özden, Ç. Volkan Özteki̇n, A. Özgür Akdemi̇r, Ali̇ Memi̇ş, Mehmet Yariş
An Abnormal Digital Rectal Examination Is An Independent Predictor Of High Radical Prostatectomy Gleason’S Score ( ≥7) In Patients With Clinically Localized Prostate Cancer, Özgür Uğurlu, Mesut Çeti̇nkaya, Cüneyt Özden, Ç. Volkan Özteki̇n, A. Özgür Akdemi̇r, Ali̇ Memi̇ş, Mehmet Yariş
Turkish Journal of Medical Sciences
Aim: The aim of this study was to investigate the importance of digital rectal examination (DRE), serum total prostate specific antigen (PSA), percent free PSA (fPSA%), and PSA density (PSAD) in the prediction of high radical prostatectomy Gleason’s scores (GSs) ≥ 7 in patients with clinically localized prostate cancer. Materials and methods: Two hundred twenty-five patients who underwent radical prostatectomy for clinically localized prostate cancer were included in the study. The patients were grouped with respect to their radical prostatectomy GSs: group 1 including the patients with GSs < 6 (n = 170) and group 2 including the ones with GSs ≥ 7 (n = 55). The groups were compared with respect to potential predictors of a high GS, which were patient age, gland volume (Vp) obtained by transrectal ultrasound, DRE, PSA, fPSA%, and PSAD. Results: The mean age, PSA, fPSA%, and PSAD values of groups 1 and 2 were 65.23 ± 7.7 and 65.05 ± 7.1 years, 11.20 ± 9.2 and 11.09 ± 6.8 ng/mL, 16.2 ± 8.6 and 15.5 ± 8.1, and 0.25 ± 0.20 and 0.28 ± 0.18 ng/mL/cc, respectively. The groups were similar with respect to mean age, PSA, fPSA%, and PSAD (P > 0.05 for all). Mean prostate volume of patients in group 2 was …
Reference Value For The Alad Enzyme Activity Ratio In Men Based On The Improvement Of Each Analytical Step Of The Colorimetric Method And The Active/Non-Active Lead Concept, Mustafa Gültepe, Hüseyi̇n Kayadi̇bi̇, Burhanetti̇n Bolat
Reference Value For The Alad Enzyme Activity Ratio In Men Based On The Improvement Of Each Analytical Step Of The Colorimetric Method And The Active/Non-Active Lead Concept, Mustafa Gültepe, Hüseyi̇n Kayadi̇bi̇, Burhanetti̇n Bolat
Turkish Journal of Medical Sciences
Aim: The ALAD enzyme activity ratio, which is highly sensitive to and specific for lead inhibition, can be used to diagnose lead-exposed individuals, but a reference value for it has not yet been established. Therefore, we aimed to establish a reference value for the ALAD activity ratio by improving each analytical step of the colorimetric method described by Mitchell et al. Materials and methods: Activators, pH, hemolyzing agents, and Ehrlich’s reagent were evaluated to obtain the optimal conditions for the restoration of lead-inhibited ALAD enzyme activity. Results: ZnCl2 and DTT were the preferred activators, the pH of sodium phosphate buffer …
Handedness Differences In Dental Traumatic Injuries Of Boxers, Saadetti̇n Dağistan, Şenol Dane, Recep Gürsoy, Bi̇nali̇ Çakur, İlhan Şen, Özkan Mi̇loğlu, Abubeki̇r Harorli
Handedness Differences In Dental Traumatic Injuries Of Boxers, Saadetti̇n Dağistan, Şenol Dane, Recep Gürsoy, Bi̇nali̇ Çakur, İlhan Şen, Özkan Mi̇loğlu, Abubeki̇r Harorli
Turkish Journal of Medical Sciences
Aim: Previous studies reported the relation of left-handedness with dental and head traumas in normal population. In the present study, we aimed to investigate the relationship between dental traumas, such as non-vitality and fracture, and left-handedness. Materials and methods: Twenty three Turkish international professional boxers were included in the study. Existence of teeth that had trauma and loss of vitality in these boxers were investigated. Results: The mean number of non-vital teeth was higher in left-handers than in right-handers for right-lower, left-upper, left-lower, and total regions, but not for the right-upper region. However, there were no significant differences between right- …
Acute Pancreatitis As An Atypical Presentation Of Henoch-Schonlein Purpura And Cystic Fibrosis, Murat Çakir, Beri̇l Di̇lber, Mukaddes Kalyoncu, Embi̇ya Di̇lber, Ayşe Aksoy, Erol Erduran
Acute Pancreatitis As An Atypical Presentation Of Henoch-Schonlein Purpura And Cystic Fibrosis, Murat Çakir, Beri̇l Di̇lber, Mukaddes Kalyoncu, Embi̇ya Di̇lber, Ayşe Aksoy, Erol Erduran
Turkish Journal of Medical Sciences
Acute pancreatitis (AP) is a rare clinical entity in childhood. Two children, aged 10 and 14 years, were hospitalized for acute abdominal pain. Clinical and laboratory findings were compatible with AP. Both patients were given supportive medications. Two days after admission, the first patient had purpuric lesions on both buttocks and lower extremities, and occult bleeding. The clinical picture was consistent with Henoch-Schonlein purpura, with pancreatitis and gastrointestinal involvement. The patient’s clinical condition improved rapidly after administration of prednisolone. The second patient had digital clubbing on physical examination, and positive sweat chloride test results led to the diagnosis of cystic …
Co-Occurrence Of Internal Carotid Artery Agenesiswith Multicystic Dysplastic Kidney, Gülgün Yilmaz Ovali, Serdar Tarhan, Petek Bayindir, Muzaffer Polat, İpek Akil
Co-Occurrence Of Internal Carotid Artery Agenesiswith Multicystic Dysplastic Kidney, Gülgün Yilmaz Ovali, Serdar Tarhan, Petek Bayindir, Muzaffer Polat, İpek Akil
Turkish Journal of Medical Sciences
Congenital absence of Internal Carotid Artery (ICA) is a rare disorder. This anomaly may be an isolated entity or may be associated with other organ, or system anomalies (1). Multicystic Dysplastic Kidney (MCDK) is a congenital mal-development in which the renal cortex is replaced by numerous cysts of multiple sizes. Urologic and non-urologic anomalies may accompany MCDK (2). In this paper, we detail a case of congenital agenesis of ICA and the existence of MCDK. To our knowledge, this is the first of such a case to be reported regarding the co-occurrence of ICA agenesis and MCDK.
Epidemiological Risk Factors For Crimean-Congo Hemorrhagic Fever Patients, Ayten Kadanali, Serpi̇l Erol, Zülal Özkurt, Kemaletti̇n Özden
Epidemiological Risk Factors For Crimean-Congo Hemorrhagic Fever Patients, Ayten Kadanali, Serpi̇l Erol, Zülal Özkurt, Kemaletti̇n Özden
Turkish Journal of Medical Sciences
Aim The aim of this study was to evaluate the epidemiological risk factors for Crimean-Congo hemorrhagic fever (CCHF) patients admitted to our hospitals between January 2004- December 2006. Materials and methods: This was a study of 63 CCHF patients whose definitive diagnosis was based on the detection of CCHF virus-specific IgM by ELISA and/or of genomic segments of the CCHF virus by real time polymerase chain reaction (RT-PCR) and 50 healthy controls. Related data were collected prospectively. Results: Twenty-two (50.8%) of the patients were female, and 31 of them (49.2%) were male. The mean age of the patients was 46 …
Use Of The Shock Index To Diagnose Acute Hypovolemia, Polat Durukan, İbrahi̇m İki̇zceli̇, Okhan Akdur, Seda Özkan, Erdoğan M. Sözüer, Levent Avşaroğullari, Güleser Akpinar
Use Of The Shock Index To Diagnose Acute Hypovolemia, Polat Durukan, İbrahi̇m İki̇zceli̇, Okhan Akdur, Seda Özkan, Erdoğan M. Sözüer, Levent Avşaroğullari, Güleser Akpinar
Turkish Journal of Medical Sciences
Aim : To determine the accuracy of the shock index in the early detection of hemodynamic changes after acute blood loss. Materials and methods: This prospective, observational study was performed on blood donors who were giving 450 mL of blood over 20 min. Vital signs of the volunteers were recorded just before blood donation, and at 1 and 5 min after donation. Shock index was calculated by dividing the heart rate by systolic blood pressure. Results: Fifty healthy donors (mean age 34±9 years) volunteered to participate in the study. Five minute post-donation heart rate (81±12 /min) and diastolic blood pressure …
The Predictive Role Of Ast Level, Prothrombin Time, And Platelet Count In The Detection Of Liver Fibrosis In Patients With Chronic Hepatitis C, Özlem Kandemi̇r, Gürbüz Polat, Güli̇z Saraçoğlu, Bahar Taşdelen
The Predictive Role Of Ast Level, Prothrombin Time, And Platelet Count In The Detection Of Liver Fibrosis In Patients With Chronic Hepatitis C, Özlem Kandemi̇r, Gürbüz Polat, Güli̇z Saraçoğlu, Bahar Taşdelen
Turkish Journal of Medical Sciences
Aim: We aimed to assess the predictive value of a combination some of basic serum biochemical markers for the diagnosis of clinically significant fibrosis in chronic hepatitis C. Materials and methods: Blood samples from 68 patients with chronic hepatitis C infection were analyzed for aspartate aminotransferase, prothrombin INR, and platelet count. The liver histopathology was evaluated using the Knodell protocol. The relationship between the serum biochemical markers and severity of the stages were examined. Results: A strong association was found between the fibrosis stage and platelet count and GUCI (P < 0.001, P = 0.035 respectively) but not APRI ([AST/ULN] / Platelet count [ ×109 /L]) × 100) (P = 0.052). The relationship between the platelet count
The Relationship Of Serum Cea And Ca 19-9 Levels To Liver Metastasis And Pancreatic Invasion In Esophageal Cancer, Ati̇la Türkyilmaz, Ati̇lla Eroğlu, Yener Aydin, Nuretti̇n Karaoğlanoğlu
The Relationship Of Serum Cea And Ca 19-9 Levels To Liver Metastasis And Pancreatic Invasion In Esophageal Cancer, Ati̇la Türkyilmaz, Ati̇lla Eroğlu, Yener Aydin, Nuretti̇n Karaoğlanoğlu
Turkish Journal of Medical Sciences
Aim: Previous studies have examined levels of CEA and CA 19-9 in esophageal cancer patients, but have not determined a significant relationship between CEA and CA 19-9 levels and liver metastasis and pancreatic invasion in patients with esophageal cancer. In this study, we compared the serum levels of CEA and CA 19-9 in patients with esophageal cancer with and without liver and pancreatic metastasis. Materials and methods: The serum levels of CEA and CA 19-9 were measured in clinic patients between January 2007 and January 2008, including 10 patients with liver metastasis (4) and pancreas invasion (6), and 40 patients …