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Articles 3721 - 3750 of 4871
Full-Text Articles in Medicine and Health Sciences
Reliability Of A Functional Test Battery Evaluating Functionality, Proprioception And Strength Of The Ankle Joint, Yavuz Yildiz, Ufuk Şeki̇r, Bülent Hazneci̇, Fati̇h Örs, Tolga Saka, Taner Aydin
Reliability Of A Functional Test Battery Evaluating Functionality, Proprioception And Strength Of The Ankle Joint, Yavuz Yildiz, Ufuk Şeki̇r, Bülent Hazneci̇, Fati̇h Örs, Tolga Saka, Taner Aydin
Turkish Journal of Medical Sciences
Aim: In contrast to the one-sided evaluation methods used in the past, combining multiple tests allows one to obtain a global assessment of the ankle joint. Materials and Methods: Twenty healthy male volunteers participated in this study. One component of the test battery included five different functional ability tests, which included: single limb hopping course, one-legged and triple-legged hop for distance, and six-meter (6-m) and cross 6-m hop for time. Ankle joint position sense and one leg standing test were used for proprioceptive evaluation. Isokinetic strength of the ankle invertor and evertor muscles were evaluated at a velocity of 120°/sec. …
Recurrent Breast Abscess Caused By Corynebacterium Amycolatum And Rewiev Of The Literature, İsmet Özaydin, Mustafa Yildirim, İdri̇s Şahi̇n, Sami̇ Doğan
Recurrent Breast Abscess Caused By Corynebacterium Amycolatum And Rewiev Of The Literature, İsmet Özaydin, Mustafa Yildirim, İdri̇s Şahi̇n, Sami̇ Doğan
Turkish Journal of Medical Sciences
Corynebacterium species are an uncommon cause of breast abscess, and Corynebacterium amycolatum is rarely described in the literature. In the present case, we report recurrent breast abscess caused by C. amycolatum in a 39-year-old patient with normal immune function. Pathological diagnosis was granulomatous mastitis. The patient was treated with incision and drainage and ampicillin-sulbactam treatment. To our knowledge, this is the second report of breast abscess caused by C. amycolatum.
Histopathological And Clinical Characteristics Of Secretory Carcinoma Of The Breast, Keri̇m Bora Yilmaz, Işin Pak, Can Atalay, Ci̇hangi̇r Özaslan
Histopathological And Clinical Characteristics Of Secretory Carcinoma Of The Breast, Keri̇m Bora Yilmaz, Işin Pak, Can Atalay, Ci̇hangi̇r Özaslan
Turkish Journal of Medical Sciences
Secretory breast carcinoma is a rare form of invasive breast carcinoma constituting less than 1% of all breast cancer cases. Since insufficient data have been compiled about this rare tumor, it is important to report every case of secretory breast carcinoma in an effort to better understand the histopathological and clinical characteristics of this tumor and to contemplate the most appropriate therapeutic approach. In this report, two adult female patients over 50 years of age and a 14-year-old girl were reviewed with a detailed immunohistochemical work-up to define the clinical and molecular characteristics of secretory breast carcinoma.
Could Obstructive Sleep Apnea Syndrome Be A Component Of Metabolic Syndrome?, Asi̇ye Kanbay, Tansu Ulukavak Çi̇ftçi̇, Oğuz Köktürk
Could Obstructive Sleep Apnea Syndrome Be A Component Of Metabolic Syndrome?, Asi̇ye Kanbay, Tansu Ulukavak Çi̇ftçi̇, Oğuz Köktürk
Turkish Journal of Medical Sciences
Aim: Obstructive sleep apnea syndrome (OSAS) is a prevalent disorder and is associated with increased cardiovascular morbidity and mortality. OSAS is independently related to the cardiovascular risk factors that comprise metabolic syndrome, atherosclerosis, acute coronary syndrome, and sudden death. The prevalence of metabolic syndrome is 30%-40% in the Turkish population. However, there are no data about the prevalence of metabolic syndrome (MS) in Turkish patients with OSAS. The aim of this study was to determine the prevalence of MS in Turkish patients with OSAS and MS-related cardiovascular diseases. Materials and Methods: The medical records of patients who were admitted to …
Investigation (In Vivo And In Vitro) Of Booster Dose Vaccine Requirement For Long-Term Protection Against Hepatitis B Virus Infection, Onur Saygun, Can Polat Eyi̇gün, İsmai̇l Yaşar Avci, Üçler Kisa, Alaaddi̇n Pahsa
Investigation (In Vivo And In Vitro) Of Booster Dose Vaccine Requirement For Long-Term Protection Against Hepatitis B Virus Infection, Onur Saygun, Can Polat Eyi̇gün, İsmai̇l Yaşar Avci, Üçler Kisa, Alaaddi̇n Pahsa
Turkish Journal of Medical Sciences
Aim: Studies have shown that no booster dose was required at least 10 to 15 years after a primary vaccination for individuals who developed protective anti-hepatitis B surface (anti-HBs) antibodies. In this study, booster dose requirement for HBV after primary immunization was investigated. Materials and Methods: Seventeen individuals vaccinated previously were enrolled in the study. They had once developed a protective level of anti-HBs antibody after immunization and their anti-HBs titer had declined to an underprotective level. Twenty uninfected and unvaccinated healthy people were chosen as controls. Lymphoproliferative response to in-vitro stimulation with hepatitis B surface antigen (HBsAg) and anti-HBs …
The Value Of Ultrasonography And Tumor Markers In The Differential Diagnosis Of Postmenopausal Ovarian Cysts, Fi̇li̇z Avşar, Emel Şi̇mşek, Sitki İsenli̇k, Mustafa Uzun, Eda Özyi̇ği̇t, Ayşegül Çi̇nkaya, Mehmet Gümüş, Emi̇ne Çelen, Işik Üstüner, Levent Keski̇n, Serpi̇l Aydoğmuş
The Value Of Ultrasonography And Tumor Markers In The Differential Diagnosis Of Postmenopausal Ovarian Cysts, Fi̇li̇z Avşar, Emel Şi̇mşek, Sitki İsenli̇k, Mustafa Uzun, Eda Özyi̇ği̇t, Ayşegül Çi̇nkaya, Mehmet Gümüş, Emi̇ne Çelen, Işik Üstüner, Levent Keski̇n, Serpi̇l Aydoğmuş
Turkish Journal of Medical Sciences
Aim: To evaluate the use of tumor markers in the differentiation of malignant and benign ovarian cysts in the postmenopausal period. Materials and Methods: The study included postmenopausal 46 patients with ovarian cysts that were assessed pre- and postoperatively using CA125 levels, ultrasonographic findings, and histopathological examination at the Obstetrics and Gynecology Clinic, Ankara Atatürk Training and Research Hospital. Results: Mean age of menopause onset was 46 years and mean duration of menopause was 11 years. Histopathological examination revealed that 28.3% of the ovarian cysts were malignant and 71.7% were benign. Of the malignant cysts, 84% were unilateral, with a …
Reproducibility Of Fuhrman Nuclear Grading Of Renal Cell Carcinoma: A Preliminary Study, Si̇bel Bektaş, Fi̇gen Barut, Burak Bahadir, Banu Doğan Gün, Ni̇lüfer Onak Kandemi̇r, Ni̇met Karadayi, Şükrü Oğuz Özdamar
Reproducibility Of Fuhrman Nuclear Grading Of Renal Cell Carcinoma: A Preliminary Study, Si̇bel Bektaş, Fi̇gen Barut, Burak Bahadir, Banu Doğan Gün, Ni̇lüfer Onak Kandemi̇r, Ni̇met Karadayi, Şükrü Oğuz Özdamar
Turkish Journal of Medical Sciences
Background: The aim of this study was to evaluate intraobserver and interobserver reproducibility of Fuhrman nuclear grading of renal cell carcinoma. Methods: Pathology slides from 46 cases of renal cell carcinoma were rescored by 2 pathologists according to the Fuhrman system. Both intraobserver and interobserver reproducibility were assessed using kappa statistics. Results: The initial Fuhrman grade was grade 1 in 4 of the cases (8.7%), grade 2 in 30 (65.2%), grade 3 in 11 (23.9%), and grade 4 in 1 (2.2%). After reviewing the slides by the same pathologist, grades were reassigned as follows: grade 1 in 8 cases (17.4%), …
The Effect Of Neuronal Nitric Oxide Synthase Inhibitor 7-Nitroindazole On The Cell Death Induced By Zinc Administration In The Brain Of Rats, M. Fati̇h Gökçe, Faruk Bağirici, Şeri̇f Demi̇r, M. Ömer Bostanci, Aysel Güven
The Effect Of Neuronal Nitric Oxide Synthase Inhibitor 7-Nitroindazole On The Cell Death Induced By Zinc Administration In The Brain Of Rats, M. Fati̇h Gökçe, Faruk Bağirici, Şeri̇f Demi̇r, M. Ömer Bostanci, Aysel Güven
Turkish Journal of Medical Sciences
Aim: To evaluate the effect of the neuronal nitric oxide synthase (nNOS) inhibitor 7-nitroindazole (7-NI) on hippocampal cell loss induced by zinc hemisulfate salt (ZnSO4·7H2O) treatment. Materials and Methods: Rats were divided into 3 groups (n = 21; 7 rats in each group): Control, Zinc, and Zinc+7-NI. In the Zinc and Zinc+7-NI (pretreatment) groups, ZnSO4·7H2O was applied intracortically to the left sensory motor cortex. The 7-NI (50 mg/kg) was injected into the third group (Zinc+7-NI) intraperitoneally 20 min prior to zinc application and daily for the next 7 days. Cell loss in the left and right hippocampal hemispheres was quantified …
Factors Affecting Adrenal Gland Involvement In Patients Who Underwent Radical Nephrectomy For Renal Cell Carcinoma, Zi̇ya Akbulut, Mehmet Tuzlali, Abdullah Erdem Canda, Karabeki̇r Ercan, Olcay Kandemi̇r, M. Derya Balbay
Factors Affecting Adrenal Gland Involvement In Patients Who Underwent Radical Nephrectomy For Renal Cell Carcinoma, Zi̇ya Akbulut, Mehmet Tuzlali, Abdullah Erdem Canda, Karabeki̇r Ercan, Olcay Kandemi̇r, M. Derya Balbay
Turkish Journal of Medical Sciences
Aim: We investigated pathological characteristics of adrenal involvement in patients who underwent radical nephrectomy (RN) for renal cell carcinoma (RCC). Materials and Methods: 49 patients (34 male, 15 female) who underwent RN and simultaneous ipsilateral adrenalectomy due to RCC were included. Patient and tumor characteristics, histopathologic features, disease stage, and radiologic computerized tomography (CT) features were studied in order to see if any of them are associated with pathological evidence of adrenal involvement. Results: Presence of adrenal irregularity (P = 0.002), venous thrombosis (P = 0.010), tumor necrosis (P = 0.031), and lymph node (LN) involvement (P = 0.013) on …
Aetiology Of Deep Vein Thrombosis In 63 Turkish Patients, Ni̇yazi̇ Çebi̇, Süleyman Tanriverdi̇
Aetiology Of Deep Vein Thrombosis In 63 Turkish Patients, Ni̇yazi̇ Çebi̇, Süleyman Tanriverdi̇
Turkish Journal of Medical Sciences
Aim: The aetiology of deep vein thrombosis differs among populations throughout the world. This study examines the aetiology of deep vein thrombosis in Turkish patients. Materials and Methods: Our study involved the treatment of 63 patients, including follow-up in our outpatient department, between November 2006 and December 2007. There were 29 female and 34 male patients with a mean age of 49.35 + 14.19 (range 25 - 85 years). Deep vein thrombosis was identified using a Doppler-/ duplex sonogram. A small pulmonary embolism was present in 5 patients. Results: Follow-up was carried out in 58 patients (92.06%). The causes of …
Demographics, Clinical Presentations And Outcomes Of Cancer Patients Admitting To Emergency Department., Nuri̇ Bozdemi̇r, Oktay Eray, Cenker Eken, Yeşi̇m Şenol, Mehmet Artaç, Mustafa Samur
Demographics, Clinical Presentations And Outcomes Of Cancer Patients Admitting To Emergency Department., Nuri̇ Bozdemi̇r, Oktay Eray, Cenker Eken, Yeşi̇m Şenol, Mehmet Artaç, Mustafa Samur
Turkish Journal of Medical Sciences
Aim: The development of new treatment strategies for cancer patients resulted in an increase of cancer patient visits to emergency departments (EDs). The purpose of this study is to determine clinical characteristics, causes, and predictors of short term prognosis of cancer patient admissions to the ED. Materials and Methods: This prospective, clinical, and observational study was carried out in an adult ED of a tertiary hospital with an annual census of 55,000. All cancer patients visiting the ED within the 6-month period were enrolled into the study and followed up at the 1st and 3rd months afterwards. Records were based …
Evaluation Of The Efficacy Of Five Dna Extraction Methods For The Detection Of Mycobacterium Tuberculosis Dna In Direct And Processed Sputum By An In-House Pcr Method, Gülnur Tarhan, İsmai̇l Ceyhan, Hülya Şi̇mşek, Serdar Tuncer
Evaluation Of The Efficacy Of Five Dna Extraction Methods For The Detection Of Mycobacterium Tuberculosis Dna In Direct And Processed Sputum By An In-House Pcr Method, Gülnur Tarhan, İsmai̇l Ceyhan, Hülya Şi̇mşek, Serdar Tuncer
Turkish Journal of Medical Sciences
Aim: DNA extraction is an important step from clinical samples for molecular diagnosis of tuberculosis by PCR. The aim of this study was to evaluate the efficacy of five DNA extraction methods [boiling, single step proteinase K, GuSCN lysis and izopropanol precipitation (Heliosis, METİS Company, TURKEY), DNA precipitation (Epicentre Technologies), and solid phase absorption (QIAamp DNA mini kit, QIAGEN, Valancia,CA)] in searching Mycobacterium tuberculosis DNA in smear positive sputum samples. Materials and Methods: A total of 50 sputum samples were extracted directly and after digested with 4% NaOH-NALC methods using 5 DNA extraction methods. All DNA extracts were studied by …
The Effects Of The Diet And Diet+Exercise On Changes In Weight During Adolescence, Çeti̇n Yaman
The Effects Of The Diet And Diet+Exercise On Changes In Weight During Adolescence, Çeti̇n Yaman
Turkish Journal of Medical Sciences
Aim: This study was carried out in 2121 primary school students in the Sakarya province of Turkey. The body mass index (BMI) of these 2121 students, between 10 and 14 years old, was calculated from their height and weight measurements. Two hundred twenty-nine students with a BMI value of 26 or above were included in the study. Materials and Methods: Diet and diet+exercise were applied to the subjects for 14 weeks under the supervision of expert dieticians and sports trainers. The subjects' heights and weights were measured by the same staff at the end of the 14-week period and their …
The Epidemiology Of Microsporidias In Humans (Malatya Sample), Ülkü Karaman, Ni̇lgün Daldal, Meti̇n Atambay, Cemi̇l Çolak
The Epidemiology Of Microsporidias In Humans (Malatya Sample), Ülkü Karaman, Ni̇lgün Daldal, Meti̇n Atambay, Cemi̇l Çolak
Turkish Journal of Medical Sciences
Aim: Microsporidias, first isolated and defined in 1857, are obligate intracellular parasites observed in animal groups and especially invertebrates. Generally homosexual patients and patients who are HIV positive and immune suppressed constitute the participants of international studies about the epidemiology of microsporidias. No previous studies about the prevalence of the parasite in Turkey have been found in the literature. This study aimed to determine the epidemiology of microsporidias in and around Malatya. Materials and Methods: Feces samples (n: 2665) from patients who presented at İnönü University Medical Faculty policlinics in 2006 with some digestive system complaints and were referred to …
The Problem Of Antimicrobial Resistance In Nosocomial Medical And Surgical Intensive Care Units Infections In A University Hospital; A Two-Year Prospective Study, Şaban İnceci̇k, Neşe Saltoğlu, Akgün Yaman, İbrahi̇m Karayaylali, Mehmet Özalevli̇, Murat Gündüz, Refi̇k Burgut
The Problem Of Antimicrobial Resistance In Nosocomial Medical And Surgical Intensive Care Units Infections In A University Hospital; A Two-Year Prospective Study, Şaban İnceci̇k, Neşe Saltoğlu, Akgün Yaman, İbrahi̇m Karayaylali, Mehmet Özalevli̇, Murat Gündüz, Refi̇k Burgut
Turkish Journal of Medical Sciences
Aim: To determine the frequency of nosocomial infections (NIs) and the antimicrobial resistance of pathogens isolated from patients admitted to 4 intensive care units (ICUs) at a university hospital. Materials and Methods: The patients were prospectively followed over 2 years in medical, surgical, and reanimation ICUs. The isolates were collected from patients with NI determined by the Center for Diseases Control and Prevention criteria. The identification was performed and susceptibility to antibiotics was determined in an automated system Sceptor (Becton Dickinson) as described by the CCLS. Results: Among the 3962 patients in the ICUs, total NI incidence was 6.9%, with …
Vocal Cord Hemangioma; A Rare Localization In Adults, Ayşe İri̇z, Evri̇m Durmaz, Hali̇t Akmansu, Muharrem Dağli, Levent Albayrak, Adi̇l Eryilmaz
Vocal Cord Hemangioma; A Rare Localization In Adults, Ayşe İri̇z, Evri̇m Durmaz, Hali̇t Akmansu, Muharrem Dağli, Levent Albayrak, Adi̇l Eryilmaz
Turkish Journal of Medical Sciences
We reported of the extremely rare adult case with hemangiomas of the vocal cord. Larengeal hemangiomas is the most common disease in infantile patients, and respiratory distress is a main symptom in this entity. But adult hemangiomas in vocal cord are very rare conditions, and hoarseness is a main symptom. A 40 years old man with hoarseness and slight difficulty in breathing was presented . Diagnostic investigation revealed a pink-purple mass which was mobile with respiration and extended from the anterior comissure to the posterior part of vocal cord. Direct laryngoscopy was performed, and it was totally excised. There was …
Glass Particles In The Frontal Sinus, Sedat Aydin, Ari̇f Şanli, Mehmet Eken, Ümi̇t Hardal
Glass Particles In The Frontal Sinus, Sedat Aydin, Ari̇f Şanli, Mehmet Eken, Ümi̇t Hardal
Turkish Journal of Medical Sciences
We present a patient that had a frontal sinus mucocele, which was the result of a traffic accident that occurred 3 years earlier. During surgery via the osteoplastic approach we observed glass particles in the left frontal sinus. As patients with foreign bodies in the paranasal sinus are not commonly seen in otolaryngological practice, especially glass particles in the frontal sinus, and papers dealing with this issue are rare in the English language literature, we present our case and a review of the literature.
Giant Lobular Capillary Hemangioma Of The Nasal Septum, Selahatti̇n Genç, Ş. Si̇nan Kürkçüoğlu, Hayri̇ye Karabulut, Baran Acar, Ümi̇t Tunçel, Semi̇h Değerli̇
Giant Lobular Capillary Hemangioma Of The Nasal Septum, Selahatti̇n Genç, Ş. Si̇nan Kürkçüoğlu, Hayri̇ye Karabulut, Baran Acar, Ümi̇t Tunçel, Semi̇h Değerli̇
Turkish Journal of Medical Sciences
Lobular capillary hemangioma is a benign, rapidly growing lesion of the skin and mucous membranes. It may rarely present as a mass of considerable size and thus entirely fill the nasal cavity; such lesions have been termed giant lobular capillary hemangioma. Its etiology remains obscure. Although it has no predilection for age, it is more common in the third decade and in females. Lobular capillary hemangioma usually involves the gingiva, lips, tongue, and buccal mucosa. However, the nasal cavity is a rare location for this lesion. The most common symptoms are epistaxis and nasal obstruction. The treatment of choice is …
Comparison Of Light Emitting Diode Phototherapy And Double Standard Conventional Phototherapy For Nonhemolytic Neonatal Hyperbilirubinemia, Nurdan Uras, Ahmet Karadağ, Alparslan Tonbul, Müsemma Karabel, Güzi̇de Doğan, Mustafa Mansur Tatli
Comparison Of Light Emitting Diode Phototherapy And Double Standard Conventional Phototherapy For Nonhemolytic Neonatal Hyperbilirubinemia, Nurdan Uras, Ahmet Karadağ, Alparslan Tonbul, Müsemma Karabel, Güzi̇de Doğan, Mustafa Mansur Tatli
Turkish Journal of Medical Sciences
Aim: To compare the efficacies and the rebound bilirubin levels of infants who received light emitting diode phototherapy and double standard conventional phototherapy. Materials and Methods: One hundred twenty-three healthy term and near term (>=35 weeks) infants requiring phototherapy for non-hemolytic hyperbilirubinemia were enrolled in the study. All infants' gestational age, type of feeding, age at phototherapy, total serum bilirubin level at initiation and termination of phototherapy, duration of phototherapy, rebound TSB levels, and type of phototherapy were recorded. Fifty-four patients received double standard conventional phototherapy (Group I) and 69 patients received light emitting diode phototherapy (Group II). Rebound …
Characterization Of The Human Gys2 Gene And Its Product Using Bioinformatic Tools, Fuat Di̇lmec, Ali̇ Ataş
Characterization Of The Human Gys2 Gene And Its Product Using Bioinformatic Tools, Fuat Di̇lmec, Ali̇ Ataş
Turkish Journal of Medical Sciences
Aim: The GYS2 gene, which encodes for glycogen synthase 2 (liver) (GS), is an enzyme responsible for the synthesis of 1,4-linked glucose chains in glycogen. The present study aimed to investigate the homology, conserved domain, and promoter and expression profiles of the human GYS2 gene among various vertebrate species using bioinformatic tools. Materials and Methods: We analyzed the homology with NCBI blast, the conserved domain with EBI ClustalW and Mega4, the promoter with Genomatix, and the expression profiles with DigiNorthern software. Results: GS proteins and their conserved domains (Glycogen_-syn) were more conserved in all the organisms investigated. There was 1 …
Acute Effect Of Speed Exercise On Nitric Oxide (No) Level Of Footballers, Özcan Saygin
Acute Effect Of Speed Exercise On Nitric Oxide (No) Level Of Footballers, Özcan Saygin
Turkish Journal of Medical Sciences
Aim: Exercise is one of the low-cost and easiest ways for improving life standards and physical fitness, and reducing body stress. Nitric oxide (NO) is defined as the ''surprising soldier mediator'' of biological systems. NO is one of the relaxation factors coming from the vascular endothelium. This relaxation in smooth muscles leads to vasodilatation in veins. The purpose of this study is to evaluate the acute effect of 20-meter sprints of footballers on NO levels. Materials and Methods: 22 footballers with an age range of 18-32 were voluntarily enrolled in the study. The heights and weights of the subjects were …
Effect Of Isoflavone On Plasma Nitrite/Nitrate, Homocysteine, And Lipid Levels In Turkish Women In The Early Postmenopausal Period: A Randomized Controlled Trial, Ni̇lgün Öztürk Turhan, Candan İltemi̇r Duvan, Fatma Bolkan, Yüksel Onaran
Effect Of Isoflavone On Plasma Nitrite/Nitrate, Homocysteine, And Lipid Levels In Turkish Women In The Early Postmenopausal Period: A Randomized Controlled Trial, Ni̇lgün Öztürk Turhan, Candan İltemi̇r Duvan, Fatma Bolkan, Yüksel Onaran
Turkish Journal of Medical Sciences
Aim: The aim of the study was to evaluate the effect of isoflavones on cardiovascular risk markers including plasma nitrite/nitrate, homocysteine, and lipid levels in Turkish women in the early postmenopausal period. Materials and Methods: Ninety participants between 42 and 59 years of age were randomly assigned to receive twice a day either isoflavone tablet (n:45) or placebo tablets (n = 45). Plasma nitrite/nitrate, homocysteine, and lipid levels were measured at baseline and after the 6 months of treatment. Results: After 6 months, isoflavone resulted in a statistically significant decrease in total cholesterol, low-density lipoproteins, triglyceride levels, serum homocysteine and …
Fibromyalgia Syndrome In Patients With Chronic Sinusitis, M. Aki̇f Öztürk, Mesut S. Tezer, Zeynep Özbalkan, Adnan Ünal, Damla Güçlü Güven, Yaşar Karaarslan
Fibromyalgia Syndrome In Patients With Chronic Sinusitis, M. Aki̇f Öztürk, Mesut S. Tezer, Zeynep Özbalkan, Adnan Ünal, Damla Güçlü Güven, Yaşar Karaarslan
Turkish Journal of Medical Sciences
Aims: Fatigue, diminished vitality, and increased bodily pain are common symptoms of chronic rhinosinusitis. On the other hand, there is an increased prevalence of rhinosinusitis symptoms among patients with unexplained chronic fatigue and/or bodily pain. Fibromyalgia syndrome is characterized by widespread pain and fatigue. In this study we aimed to determine the prevalence of fibromyalgia among patients with chronic sinusitis. Materials and Methods: This study included 58 consecutive patients who were diagnosed as chronic rhinosinusitis (24 women and 34 men, mean age: 42.61 ± 10.97). Computed tomography (CT) imaging of the paranasal sinuses and nasal endoscopic examinations were performed for …
Plasma Resistin And Leptin Levels In Overweight And Lean Patients With Rheumatoid Arthritis, Nai̇me Canoruç, Ebru Kale, Ayşe Di̇cle Turhanoğlu, Şehmus Özmen, Ceyla Ogün, Abdurrahman Kaplan
Plasma Resistin And Leptin Levels In Overweight And Lean Patients With Rheumatoid Arthritis, Nai̇me Canoruç, Ebru Kale, Ayşe Di̇cle Turhanoğlu, Şehmus Özmen, Ceyla Ogün, Abdurrahman Kaplan
Turkish Journal of Medical Sciences
Aim: Adipocytokines are now considered important players in the etiopathogenesis of numerous metabolic and inflammatory disorders. However, plasma leptin and resistin levels in rheumatoid arthritis (RA) are still unclear. We aimed to investigate the plasma levels of leptin and resistin in patients with rheumatoid arthritis and to compare them with controls. Materials and Methods: Consecutive 52 patients with RA were compared with 52 control subjects in terms of mean leptin and resistin levels. Results: Patients with RA showed considerably higher plasma levels of leptin (34.3 ± 27.9 vs. 11.1 ± 4.1) and resistin (4.8 ± 0.7 vs. 4.0 ± 1.3) …
Isolated Fungal Sinusitis Of The Sphenoid Sinus, Ayşe İri̇z, Muharrem Dağli, Hali̇t Akmansu, Özge Han, Bengi̇ Arslan, Adi̇l Eryilmaz
Isolated Fungal Sinusitis Of The Sphenoid Sinus, Ayşe İri̇z, Muharrem Dağli, Hali̇t Akmansu, Özge Han, Bengi̇ Arslan, Adi̇l Eryilmaz
Turkish Journal of Medical Sciences
Isolated fungal sphenoid sinusitis is a rare entity. Fungal sinusitis is mostly seen in immunocompromised patients and is characterized by invasive progression. We describe a immunologically competent patient with isolated aspergillosis in her sphenoid sinus.
A Rare Cause Of Neonatal Hypocalcemia: Malignant Infantile Osteopetrosis, Hakan Uzun, Ebru Yilmaz Keski̇n, Dursun Ali̇ Şenses, Ayhan Erdem, Bünyami̇n Di̇ki̇ci̇, Kenan Kocabay
A Rare Cause Of Neonatal Hypocalcemia: Malignant Infantile Osteopetrosis, Hakan Uzun, Ebru Yilmaz Keski̇n, Dursun Ali̇ Şenses, Ayhan Erdem, Bünyami̇n Di̇ki̇ci̇, Kenan Kocabay
Turkish Journal of Medical Sciences
Malignant infantile osteopetrosis (MIOP) is a rare inherited bone disease characterized by reduced or dysregulated activity of osteoclasts, which results in generalized osteosclerosis. This leads to abnormal bone marrow cavity formation and to the clinical signs and symptoms of bone marrow failure and nerve compression. Symptoms related to early or late hypocalcemia may appear as the first presentation of MIOP in a newborn. We present a 14-day-old boy with neonatal hypocalcaemia due to MIOP.
A Case Of Common Variable Immunodeficiency Disease And Thyroid Amyloidosis, Di̇lek Soysal, Ebru Türkkan, Volkan Karakuş, Erhan Tatar, Özlem Yersal Kabayeği̇t, Arzu Avci
A Case Of Common Variable Immunodeficiency Disease And Thyroid Amyloidosis, Di̇lek Soysal, Ebru Türkkan, Volkan Karakuş, Erhan Tatar, Özlem Yersal Kabayeği̇t, Arzu Avci
Turkish Journal of Medical Sciences
A 37-year-old male patient with fever, mild respiratory distress, diffuse goiter, and hepatosplenomegaly was admitted to our hospital. Clinical and laboratory findings showed that he had recurrent respiratory tract infections-namely bronchiectasis-due to common variable immunodeficiency disease (CVID) and AA-type amyloid deposition in the thyroid gland. Although recurrent infections as a consequence of inadequate gammaglobulin (IVIG) substitution therapy are regarded as the main cause of the development of amyloidosis, amyloidosis in a patient with hypo/agammaglobulinemia is extremely rare. In this report we discuss the association of CVID and recurrent respiratory tract infections with secondary amyloidosis restricted to one organ, the thyroid …
Disseminated Herpes Zoster Infection In A Patient With Lymphoma, Behi̇ce Kurtaran, Semra Paydaş, Aslihan Candevi̇r, Süheyla Kömür, Hasan Sali̇h Zeki̇ Aksu
Disseminated Herpes Zoster Infection In A Patient With Lymphoma, Behi̇ce Kurtaran, Semra Paydaş, Aslihan Candevi̇r, Süheyla Kömür, Hasan Sali̇h Zeki̇ Aksu
Turkish Journal of Medical Sciences
Immunosuppression facilitates varicella zoster virus (VZV) reactivation in immunocompromised patients. Atypical presentation such as disseminated disease of herpes zoster infection has been described in immunosuppressed patients. One of the best choices of therapy in herpes zoster infection is acyclovir, but long-term therapy may cause resistance to it. In this report a disseminated herpes zoster infection is described in a patient with T cell lymphoma after acyclovir/valacyclovir therapy. The infection was irresponsive to acyclovir and valacyclovir and we were unable to control the infection because it was not possible to obtain foscarnet and the patient died due to Staphylococcus epidermis sepsis.
Primary Mucosal Desmoplastic Melanoma Of The Gingiva, Reşi̇t Doğan Köseoğlu, İbrahi̇m Aladağ, Engi̇n Sezer, Ni̇lüfer Özkan
Primary Mucosal Desmoplastic Melanoma Of The Gingiva, Reşi̇t Doğan Köseoğlu, İbrahi̇m Aladağ, Engi̇n Sezer, Ni̇lüfer Özkan
Turkish Journal of Medical Sciences
Desmoplastic melanoma (DM) is a very rare variant of malignant melanoma. Mucosal involvement in DM is exceedingly rare and the differential diagnosis is problematic for surgical pathologists. To the best of our knowledge only 16 cases of DM originating from mucosal surfaces of the oral cavity have been described in the literature. Herein we describe a 59-year-old male with primary DM of the oral mucosa and discuss the status of p53, caspase-3, and FasL (Fas ligand) in the pathogenesis of this rare disease.
A Patient With Addison's Disease Whose Sixth Pregnancy Resulted In A Healthy Baby, Yusuf Aydin, Merve Yilmaz, Di̇lek Berker, İhsan Üstün, Tuncay Deli̇başi, Serdar Güler
A Patient With Addison's Disease Whose Sixth Pregnancy Resulted In A Healthy Baby, Yusuf Aydin, Merve Yilmaz, Di̇lek Berker, İhsan Üstün, Tuncay Deli̇başi, Serdar Güler
Turkish Journal of Medical Sciences
No abstract provided.