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Full-Text Articles in Medicine and Health Sciences

Factors Affecting Quality Of Life In Patients With Coronary Heart Disease, Tahi̇r Durmaz, Özcan Özdemi̇r, Burcu Akyunak Özdemi̇r, Telat Keleş, Ni̇hal Akar Bayram, Engi̇n Bozkurt Jan 2009

Factors Affecting Quality Of Life In Patients With Coronary Heart Disease, Tahi̇r Durmaz, Özcan Özdemi̇r, Burcu Akyunak Özdemi̇r, Telat Keleş, Ni̇hal Akar Bayram, Engi̇n Bozkurt

Turkish Journal of Medical Sciences

Background: Cardiovascular diseases are currently the most common cause of death worldwide and associated with significant impairment of quality of life (QOL). In this study, we aimed to evaluate the QOL patients with coronary heart disease (CHD) in our country and the factors associated with QOL in these patients. Materials and Methods: The study population was composed of 85 patients diagnosed with stable CHD. The data were collected using Ferrans and Powers' Quality of Life Index Cardiac Version- IV and the query designed by the investigators. Results: Eighty-five patients (29 female, 56 male; ages between 38 and 72 years) were …


The Relation Between Gleason Score, And Nuclear Size And Shape Factors In Prostatic Adenocarcinoma, Si̇bel Bektaş, Burak Bahadir, Banu Doğan Gün, Gürkan Kerti̇ş, Şükrü Oğuz Özdamar Jan 2009

The Relation Between Gleason Score, And Nuclear Size And Shape Factors In Prostatic Adenocarcinoma, Si̇bel Bektaş, Burak Bahadir, Banu Doğan Gün, Gürkan Kerti̇ş, Şükrü Oğuz Özdamar

Turkish Journal of Medical Sciences

Aim: The aim of this study was to assess the size and shape characteristics of prostatic adenocarcinoma cell nuclei using a computer-assisted analysis system, and to compare the results with the Gleason score. Materials and Methods: Morphometric nuclear parameters, such as roundness factor, form ellipse, area, length, and perimeter, were evaluated based on specimen slides of 130 prostatic adenocarcinoma cases (77% needle biopsies and 23% prostatectomy specimens) using a computerized image analysis system. Correlation analysis between Gleason score and morphometric results was performed. Results: The Gleason score was correlated with mean nuclear area (r = 0.516, P = 0.01), mean …


Human Chorionic Gonadotropin Levels In Serum And Follicular Fluid Are Correlated With Body Mass Index Rather Than The Route Of Administration Of Purified Hcg In Art Cycles, Özlem Moralioğlu Üçkardeşler, Sevtap Kiliç, Gülnur Özakşi̇t, Çi̇ğdem Kunt, Ayça Işik, Beri̇l Yüksel, Leyla Mollamahmutoğlu Jan 2009

Human Chorionic Gonadotropin Levels In Serum And Follicular Fluid Are Correlated With Body Mass Index Rather Than The Route Of Administration Of Purified Hcg In Art Cycles, Özlem Moralioğlu Üçkardeşler, Sevtap Kiliç, Gülnur Özakşi̇t, Çi̇ğdem Kunt, Ayça Işik, Beri̇l Yüksel, Leyla Mollamahmutoğlu

Turkish Journal of Medical Sciences

Aim: To investigate hCG levels in follicular fluid and serum after intramuscular (IM) or subcutaneous (SC) administration of purified hCG, and their association with oocyte maturation and body mass index (BMI) in women undergoing IVF-ET. Materials and Methods: The study included 160 infertile women that were recruited between April and June 2007. Standard-dose long IVF protocols were used for ovulation induction. SC or IM injections were used to administer hCG. BMI, oocyte maturity, and serum and follicular fluid hCG levels were the main outcome measurements. Results: hCG levels in serum and follicular fluid in the 2 groups were similar. A …


Prevalence Of Sen Virus Genotype-D And Genotype-H Among Haemodialysed Patients, Seda Tezcan, Nuran Deli̇ali̇oğlu, Mehmet Sami̇ Seri̇n, Gönül Aslan, Naci̇ Ti̇fti̇k, Gürol Emekdaş Jan 2009

Prevalence Of Sen Virus Genotype-D And Genotype-H Among Haemodialysed Patients, Seda Tezcan, Nuran Deli̇ali̇oğlu, Mehmet Sami̇ Seri̇n, Gönül Aslan, Naci̇ Ti̇fti̇k, Gürol Emekdaş

Turkish Journal of Medical Sciences

Aim: A recently discovered DNA virus (SEN virus) has been assumed to be responsible for post-transfusion hepatitis in humans. Phylogenetic analysis of the SEN virus (SEN-V) has revealed the existence of 8 different genotypes (A-H). SEN-V genotype-H (SENV-H) and SEN-V genotype-D (SENV-D) have been described as most closely associated with post-transfusion hepatitis. So far, it is unclear whether patients on maintenance haemodialysis are at increased risk for acquiring the SEN virus. The aim of the present study was to investigate the prevalence of SENV-D and SENV-H among patients on maintenance haemodialysis. Materials and Methods: Serum samples derived from 100 haemodialysed …


Survival In Esophageal Cancer Patients With Hematogenous Distant Organ Metastases, Ati̇la Türkyilmaz, Ati̇lla Eroğlu, Yener Aydin, Ömer Yilmaz, Nuretti̇n Karaoğlanoğlu Jan 2009

Survival In Esophageal Cancer Patients With Hematogenous Distant Organ Metastases, Ati̇la Türkyilmaz, Ati̇lla Eroğlu, Yener Aydin, Ömer Yilmaz, Nuretti̇n Karaoğlanoğlu

Turkish Journal of Medical Sciences

Objective: Esophageal cancer is a rapidly progressive cancer. In the majority of patients local invasion or distant metastasis may be present at the time of diagnosis. The present study reviewed the records of esophageal cancer patients with hematogenous distant organ metastases with the aim of reporting primary tumor location, histological type, location of metastases, and survival rates, according to treatment administered. Method: Distant organ metastasis was detected in 50 of 316 consecutive patients that presented to the Thoracic Surgery Department of Atatürk University between 2002 and 2007. Patient age and gender, tumor location, history of esophagectomy, metastasis organ, treatment type, …


Hiv/Aids Knowledge Among A Group Of Youngsters Under Social Protection In Turkey, Veli̇ Duyan, Gülsüm Çamur Duyan Jan 2009

Hiv/Aids Knowledge Among A Group Of Youngsters Under Social Protection In Turkey, Veli̇ Duyan, Gülsüm Çamur Duyan

Turkish Journal of Medical Sciences

Aim: A number of radical changes in social conditions have created new hazards, such as STDs and HIV/AIDS, for young people. The purpose of this research was to determine the level of HIV/AIDS knowledge and information sources of the youngsters who are under social protection in Turkey. Materials and Methods: Participants of the study were 649 female and 739 males between the ages of 12 and 24 (M = 15.3, SD = 1.92) who are under social protection in Turkey. Data were collected using a demographic questionnaire, sources of HIV/AIDS information questionnaire, and HIV/AIDS questionnaire. The questionnaires were administered in …


Endovascular Treatment Of A Cerebral Single-Hole Arteriovenous Fistula Associated With A Giant Aneurysmal Sac In A Pediatric Patient, Si̇bel Bakan, Meli̇ke Kale, Hüseyi̇n Akan Jan 2009

Endovascular Treatment Of A Cerebral Single-Hole Arteriovenous Fistula Associated With A Giant Aneurysmal Sac In A Pediatric Patient, Si̇bel Bakan, Meli̇ke Kale, Hüseyi̇n Akan

Turkish Journal of Medical Sciences

Cerebral arteriovenous fistulas (AVFs) are rare in childhood and are generally associated with arteriovenous malformations (AVMs). They may lead to an increase in intracerebral pressure, seizure, hemorrhage, or cardiac decompression. They may be treated with endovascular embolization. Herein we present the radiological findings, before and after endovascular treatment, of a pediatric patient with a cerebral AVF associated with a giant aneurysmal sac.


The Effect Of Music On Cognitive Emotional Response In Undergraduate Students Studying Health-Related Courses: A Pilot Study, U. Alalami, S. K. Alalami, Ross Gordon Cooper Jan 2009

The Effect Of Music On Cognitive Emotional Response In Undergraduate Students Studying Health-Related Courses: A Pilot Study, U. Alalami, S. K. Alalami, Ross Gordon Cooper

Turkish Journal of Medical Sciences

No abstract provided.


Disseminated Superficial Actinic Porokeratosis: A Case Report, Asli Eralp, Yeşi̇m Kaymak Jan 2009

Disseminated Superficial Actinic Porokeratosis: A Case Report, Asli Eralp, Yeşi̇m Kaymak

Turkish Journal of Medical Sciences

Disseminated superficial actinic porokeratosis (DSAP) is a type of porokeratosis observed in parts of the skin exposed to intense sunlight and usually appears in the third or fourth decade of life. Since it is a rare disorder, herein we present our experience of a 57-year-old man with DSAP. Dermatological examination of the patient revealed pink/red multiple papular lesions, ranging in diameter from 0.5 to 1 cm, with an atrophic center and hyperkeratotic contours limited to sun-exposed skin parts especially in the extremities and rarely in trunk. Cryotherapy was effective in healing the lesions.


Long-Term Stays In Hospitals: A Case Report, Çi̇çek Hocaoğlu Jan 2009

Long-Term Stays In Hospitals: A Case Report, Çi̇çek Hocaoğlu

Turkish Journal of Medical Sciences

Inpatients experience frequent psychiatric disorders. Long-term stays in hospitals increase this risk of having a psychiatric disorder and cause negative effects on their ongoing treatments. Several studies emphasized that physicians should be careful for psychiatric disorders affecting the treatment process of inpatients as well as the period of stay in the hospital. This study is a case report. Psychodynamic formulation has been made evaluating the psychiatric disease history and psychodynamic and psychosocial history as well as through psychological tests.


The Effects Of Cigarette Smoking On Serum Oxidant Status, And Cholesterol, Homocysteine, Folic Acid, Copper, And Zinc Levels In University Students, İmge B. Ergüder, Asli Uçar, Işil Aritürk, Toker Ergüder, Aslihan Avci, Seni̇ha Hasi̇pek, Kadi̇rhan Sunguroğlu Jan 2009

The Effects Of Cigarette Smoking On Serum Oxidant Status, And Cholesterol, Homocysteine, Folic Acid, Copper, And Zinc Levels In University Students, İmge B. Ergüder, Asli Uçar, Işil Aritürk, Toker Ergüder, Aslihan Avci, Seni̇ha Hasi̇pek, Kadi̇rhan Sunguroğlu

Turkish Journal of Medical Sciences

Aim: To examine the effect of cigarette smoking on serum oxidative damage and oxidant status in university students. Materials and Methods: Subjects were randomly chosen from among Ankara University Faculty of Science students. The study was performed at the Ankara University Faculty of Health Sciences, Department of Nutrition and Dietetics, and the Ankara University Faculty of Medicine, Department of Biochemistry. In all, 44 volunteer (22 smokers and 22 non-smokers) students participated in the study. Malondialdehyde, sensitivity to oxidation (SO), and antioxidant potential (AOP), and total cholesterol, HDL cholesterol, LDL cholesterol, VLDL cholesterol, homocysteine, folic acid, copper, and zinc levels were …


Aromatase Inhibitors In Infertile Patients: Effects On Seminal Parameters, Serum And Seminal Plasma Testosterone Levels, And Estradiol Levels During Short-Term Follow-Up, M. Murad Başar, Devri̇m Tuğlu Jan 2009

Aromatase Inhibitors In Infertile Patients: Effects On Seminal Parameters, Serum And Seminal Plasma Testosterone Levels, And Estradiol Levels During Short-Term Follow-Up, M. Murad Başar, Devri̇m Tuğlu

Turkish Journal of Medical Sciences

Aim: To evaluate the effects of an aromatase inhibitor (anastrozole) on seminal parameters, and on serum and seminal plasma testosterone/estradiol ratios in infertile patients, as well as to clarify its place among empirical infertility treatment modalities. Patients and Methods: The study included 32 patients with spermatozoa numbering > 5 million/mL in ejaculate and a serum testosterone/estradiol ratio < 0.14. Anastrozole, an aromatase-inhibiting agent, was given (1 mg b.i.d.) and patients were re-evaluated 2 months later based on semen analysis, and measurements of serum and seminal plasma testosterone and estradiol levels. Results: Semen analysis parameters before and after treatment, respectively, were as follows: number of spermatozoa: 12.4 ± 4.1 million/mL and 22.3 ± 5.7 million/mL; motility: 33.4 ± 4.2% and 47.6 ± 7.4%; normal morphology: 5.4 ± 1.3% and 8.9 ± 2.7%. Differences between the values before and after treatment were statistically significant (P < 0.05). Serum testosterone level was 4.1 ± 1.2 ng/mL, estradiol level was 52.1 ± 9.4 pg/mL, and testosterone/estradiol ratio was 0.13 ± 0.03 at the beginning of treatment. These values were 3.2 ± 0.6 ng/mL, 68.4 ± 7.3 pg/mL, and 0.05 ± 0.001, respectively, in seminal plasma. Following 2 months of anastrozole treatment, testosterone and estradiol levels, and the testosterone/estradiol ratio showed statistically significant changes in serum and seminal plasma. While testosterone levels significantly increased, estradiol levels decreased (serum P_T = 0.001, P_{E2} = 0.001; seminal plasma P_T = 0.001, P_{E2} = 0.001). Conclusion: Aromatase inhibitors are a potential treatment method for infertile male patients with increased plasma estradiol levels and decreased plasma testosterone/estradiol ratios.


Comparison Of Semen Parameters Between Pregnant And Nonpregnant Couples With Male Factor Infertility During Intrauterine Insemination*, Candan İltemi̇r Duvan, Bülent Berker, Ömer Bayrak, Kaan Aydos, Ni̇lgün Turhan Öztürk, Hakan Şatiroğlu Jan 2009

Comparison Of Semen Parameters Between Pregnant And Nonpregnant Couples With Male Factor Infertility During Intrauterine Insemination*, Candan İltemi̇r Duvan, Bülent Berker, Ömer Bayrak, Kaan Aydos, Ni̇lgün Turhan Öztürk, Hakan Şatiroğlu

Turkish Journal of Medical Sciences

Aim: To compare the semen parameters between pregnant and nonpregnant couples with male factor infertility during intrauterine insemination (IUI). Materials and Methods: The study included a total of 156 IUI cycles performed in our center from January 2005 to December 2006 with the indication of male infertility. IUI cycles were divided into 2 groups: group 1 pregnancy (24 cycles) and group 2 (132 cycles) nonpregnancy cycles. Results: In both groups, progressive motility of neither initial nor processed sperm specimens was significantly different (P > 0.05). When comparisons of semen parameters in groups were performed in the initial specimen, sperm concentration and …


The Clinical And Laboratory Characteristics Of Vitamin D Intoxication In Children, Hakan Döneray, Behzat Özkan, Asuman Özkan, Celaletti̇n Koşan, Zerri̇n Orbak, Cahi̇t Karakelleoğlu Jan 2009

The Clinical And Laboratory Characteristics Of Vitamin D Intoxication In Children, Hakan Döneray, Behzat Özkan, Asuman Özkan, Celaletti̇n Koşan, Zerri̇n Orbak, Cahi̇t Karakelleoğlu

Turkish Journal of Medical Sciences

Aim: In this retrospective study, patients with vitamin D intoxication (VDI) were evaluated with respect to clinical and laboratory characteristics, treatment protocols and complications. Materials and Methods: The medical records of 27 children with VDI between 2003 and 2008 were investigated. Data included age, gender, nutritional status, dose and duration of prophylactic/therapeutic vitamin D, the reasons for vitamin D therapy prescription, clinical signs and symptoms, laboratory findings, therapy protocol for VDI, and complications. Results: The mean dose of vitamin D prescribed to the patients was 600,000 U (range: 300,000-1,200,000 U). The most prominent reason (80.9%) for physician prescription of vitamin …


Evaluation Of Osteoporotic Fractures In A Group Of Turkish Women, Ersi̇n Odabaşi, Mustafa Turan, Faruk Tekbaş, Mustafa Kutlu Jan 2009

Evaluation Of Osteoporotic Fractures In A Group Of Turkish Women, Ersi̇n Odabaşi, Mustafa Turan, Faruk Tekbaş, Mustafa Kutlu

Turkish Journal of Medical Sciences

Aims: The frequency of osteoporotic fractures varies from one country to another. Epidemiologic data related to osteoporotic fractures is limited in Turkey. In this study, we aimed to explore the frequency of osteoporotic fractures in osteoporotic women on the basis of our outpatient clinic data. Additionally, we aimed to define the relationship between osteoporotic fractures and age, menopause status, bone mineral density (BMD), and body mass index (BMI). Materials and Methods: This is a retrospective chart review of 934 osteoporotic women, older than 50 years of age, seen from March 1998 through July 2005 at a musculoskeletal disease outpatient clinic …


The Effects Of Nitric Oxide On Rat Stomach Injury Induced By Acetylsalicylic Acid, Murat Yağmurca, Muharrem Uçar, Ersi̇n Fadillioğlu, Hasan Erdoğan, Feral Öztürk Jan 2009

The Effects Of Nitric Oxide On Rat Stomach Injury Induced By Acetylsalicylic Acid, Murat Yağmurca, Muharrem Uçar, Ersi̇n Fadillioğlu, Hasan Erdoğan, Feral Öztürk

Turkish Journal of Medical Sciences

Aim: Acetylsalicylic acid (ASA, aspirin), which is one of the most frequently used drugs in the world, causes severe gastric mucosal injury. Nitric oxide (NO) is synthesized from L-arginine by nitric oxide synthase (NOS). NOS can be inhibited by Nω-nitro-L-arginine methyl ester (L-NAME) and stimulated by supplementing the diet with L-arginine (L-Arg). The aim of this study was to investigate the role of NO on gastric mucosal injury induced by ASA. Materials and Methods: Male Sprague-Dawley rats were divided into seven groups: control, ASA, ASA+L-NAME, ASA+L-Arg, ASA+L-Arg+L-NAME, only L-NAME, and only L-Arg groups. After administration of the drugs, the rats …


Comparison Of Human Milk, Cow´S Milk And Infant Formulas For Their Antifungal Effects Against Environmental Fungi, Emi̇n Mete, Ferhat Çatal, Cüneyt Tayman, Nurdan Uras, Hali̇se Akça, Mustafa Ulukanligi̇l, Fati̇h Özkaragöz Jan 2009

Comparison Of Human Milk, Cow´S Milk And Infant Formulas For Their Antifungal Effects Against Environmental Fungi, Emi̇n Mete, Ferhat Çatal, Cüneyt Tayman, Nurdan Uras, Hali̇se Akça, Mustafa Ulukanligi̇l, Fati̇h Özkaragöz

Turkish Journal of Medical Sciences

Aim: Breast-feeding is generally accepted as the optimal method of feeding infants. The purpose of the present study was to investigate and compare the antifungal effect of human milk with infant formula and cow´s milk. Materials and Methods: Eighty Sabouraud agar petri dishes were separated into eight groups. All petri dish lids were closed and incubated, after 15 minutes uncovered. The first group was used to detect the fungal flora of the environmental air. The second group was rubbed with human milk. The third group was rubbed with 0.9% NaCl solution. Fourth group was rubbed with cow´s milk. Fifth, 6, …


Evaluation Of The Knowledge Of Hospital Cleaning Staff About Prevention Of Nosocomial Infections, Tansu Yamazhan, Meltem Işikgöz Taşbakan, Şebnem Çalik, Hüsnü Pullukçu, Oğuz Reşat Si̇pahi̇, Sercan Ulusoy Jan 2009

Evaluation Of The Knowledge Of Hospital Cleaning Staff About Prevention Of Nosocomial Infections, Tansu Yamazhan, Meltem Işikgöz Taşbakan, Şebnem Çalik, Hüsnü Pullukçu, Oğuz Reşat Si̇pahi̇, Sercan Ulusoy

Turkish Journal of Medical Sciences

Aims: Detection of risk groups and infection sources and awareness of the routes of transmission of infections are important for prevention of hospital infections. In this study, we aimed to evaluate the knowledge level and the behavior models of hospital cleaning staff about nosocomial infections. Materials and Methods: A 21-item questionnaire about nosocomial infections was administered to the hospital cleaning staff. Results: Out of 290 hospital cleaning staff, 240 (82.7%, 122 male, 118 female, aged 36.2±8.7) were included in the study. When evaluated according to their educational status, 55.4% had graduated from primary school. Fifty-four percent of the staff had …


Effects Of Peer And Group Education On Knowledge, Beliefs And Breast Self-Examination Practice Among University Students In Turkey, Özgül Karayurt, Akli̇me Di̇cle, Arzu Tuna Malak Jan 2009

Effects Of Peer And Group Education On Knowledge, Beliefs And Breast Self-Examination Practice Among University Students In Turkey, Özgül Karayurt, Akli̇me Di̇cle, Arzu Tuna Malak

Turkish Journal of Medical Sciences

Aims: To determine the effects of peer and group education on knowledge and beliefs about breast cancer and performance of breast self–examination (BSE). Materials and Methods: The study included a total of 193 female university students, of whom 59 were assigned to peer education and 134 to group education. Data collected at baseline and after six months included sociodemographic characteristics, knowledge of breast cancer and BSE and performance of BSE forms, and Champion´s Health Belief Model Scale. Data were analyzed using the chi-square, McNemar chi-square, independent Student´s t, and paired Student´s t tests. Results: Mean knowledge scores increased from 42.08 …


Viral Etiology And Symptoms Of Acute Upper Respiratory Tract Infections In Children, Emi̇n Ünüvar, İsmai̇l Yildiz, Ayşe Kiliç, Seyhan Selvi̇ Aslan, Bülent Çakal, Sadik Toprak, Seli̇m Badur, Fatma Oğuz, Müjgan Sidal Jan 2009

Viral Etiology And Symptoms Of Acute Upper Respiratory Tract Infections In Children, Emi̇n Ünüvar, İsmai̇l Yildiz, Ayşe Kiliç, Seyhan Selvi̇ Aslan, Bülent Çakal, Sadik Toprak, Seli̇m Badur, Fatma Oğuz, Müjgan Sidal

Turkish Journal of Medical Sciences

Aims: To determine viral causes of acute upper respiratory tract infections and clinical findings in children living in Istanbul, Turkey. Materials and Methods: This prospective study was carried out in 234 outpatient children (age range: 1-180 months) with acute upper respiratory tract infections, seen in the outpatient clinic at Istanbul Medical School Children´s Hospital. After clinical findings were recorded, nasal swab specimens were taken. In 201 specimens collected, influenza-A and -B, adenovirus, respiratory syncytial virus, and parainfluenza viruses were studied using direct fluorescence antibody, polymerase chain reaction (PCR), and cell culture techniques. Results: Rate of virus isolation was 29.8% (60/201). …


Screening For Chlamydia Trachomatis Infection Using Direct Fluorescein Antibody Method In Female Sex Workers Registered In Ankara, Turkey: Pros And Cons, Pinar Zarakolu, Server Yağci, Banu Çakir, Serhat Ünal Jan 2009

Screening For Chlamydia Trachomatis Infection Using Direct Fluorescein Antibody Method In Female Sex Workers Registered In Ankara, Turkey: Pros And Cons, Pinar Zarakolu, Server Yağci, Banu Çakir, Serhat Ünal

Turkish Journal of Medical Sciences

Aim: This study aimed to screen for Chlamydia trachomatis infection by direct fluorescein antibody (DFA) method in a high-risk population, registered female sex workers (FSWs) in Ankara, Turkey, to investigate the advantages and disadvantages of using this method in a routine screening program of the FSW population. Materials and Methods: All registered FSWs (n = 152) in Ankara were enrolled in the study. None of them were showing any genital signs or symptoms of sexually transmitted infections (STIs). Endocervical swabs were collected and examined for C. trachomatis by DFA method (Fluorotect Chlamydia, Omega Diagnostics, UK). Cellular adequacy of the specimens …


Salmonella-Infected Chronic Subdural Hematoma, Adem Aslan, Olcay Eser, Murat Coşar, Ramazan Albayrak Jan 2009

Salmonella-Infected Chronic Subdural Hematoma, Adem Aslan, Olcay Eser, Murat Coşar, Ramazan Albayrak

Turkish Journal of Medical Sciences

We present herein a case in which salmonella infected a pre-existing chronic subdural hematoma. A one-year-old male infant was admitted to our hospital with complaints of loss of consciousness, seizure, and left hemiparesis. Irrigation and drainage through two burr-holes were performed to the left frontoparietal region with the diagnosis of chronic subdural hematoma according to CT findings. Operative findings revealed an infected subdural hematoma. Salmonella typhi grew in cultures of the subdural hematoma. According to the result of the culture antibiogram, ciprofloxacin therapy was initiated. Because of continued lethargy six days after the operation, a contrasted MRI was performed. The …


Relation Between Objectively Measured Growth Determinants And Ambulation In Children With Cerebral Palsy, Ni̇lüfer Kutay Ordu Gökkaya, Asli Çalişkan, Di̇lek Karakuş, Hali̇l Uçan Jan 2009

Relation Between Objectively Measured Growth Determinants And Ambulation In Children With Cerebral Palsy, Ni̇lüfer Kutay Ordu Gökkaya, Asli Çalişkan, Di̇lek Karakuş, Hali̇l Uçan

Turkish Journal of Medical Sciences

Aims: Cerebral palsy (CP) is a well-known neurodevelopmental condition beginning in early childhood and persisting throughout one´s life span. Feeding problems and eating impairments in CP children are well documented in the literature. The aims of our study were to determine the prevalence of linear growth retardation and the other growth determinants in this patient group and to identify the contributing factors and their relationship with ambulation. Materials and Methods: A cross-sectional and prospective study was carried out between March 2007 and July 2007 in our pediatric inpatient rehabilitation service, and a total of 34 CP patients (22 male, 12 …


Examining Antibiotic Use At An Education And Research Hospital In Turkey: Point Prevalence Results, Gül R. Yilmaz, Cemal Bulut, Fati̇h Yildiz, Selcan Arslan, M. Arzu Yetki̇n, Ali̇ Pekcan Demi̇röz Jan 2009

Examining Antibiotic Use At An Education And Research Hospital In Turkey: Point Prevalence Results, Gül R. Yilmaz, Cemal Bulut, Fati̇h Yildiz, Selcan Arslan, M. Arzu Yetki̇n, Ali̇ Pekcan Demi̇röz

Turkish Journal of Medical Sciences

Aims: Antimicrobial drugs are among the most commonly prescribed drugs in hospitals. Inappropriate use of antibiotics leads to development of antimicrobial resistance. The aims of this study were to determine the rate of antibiotic usage in hospitalized patients, the reasons for antibiotic therapy, irrational uses, and the rates of irrational use in patients hospitalized in Ankara Education and Research Hospital. Materials and Methods: A point prevalence surveillance study was performed on 27 April 2006 at Ankara Education and Research Hospital. Data of all hospitalized patients were collected. Results: On the day of the study, 153 patients (36.2%) out of 422 …


Papillary Carcinoma On The Thyroglossal Cyst Wall, Ş. Si̇nan Kürkçüoğlu, Selahatti̇n Genç, Ümi̇t Tunçel, Funda Demi̇rağ Jan 2009

Papillary Carcinoma On The Thyroglossal Cyst Wall, Ş. Si̇nan Kürkçüoğlu, Selahatti̇n Genç, Ümi̇t Tunçel, Funda Demi̇rağ

Turkish Journal of Medical Sciences

Thyroglossal duct cysts are usually located at the midline of the neck. While the coexistence of a carcinoma in a thyroglossal duct cyst is extremely rare, papillary carcinoma represents almost 80% of the cases. Its treatment is usually decided based on postoperative histopathological examinations. Although the Sistrunk procedure is often seen as adequate, the treatment of thyroglossal duct cysts remains controversial. In the present study, the Sistrunk procedure was used to excise a thyroglossal duct cyst in a 24-year-old female. Papillary carcinoma was confirmed with the histopathological examination following the surgery. We did not perform thyroidectomy, neck dissection or radioactive …


Is The Traditional Treatment Approach Adequate In Children With Adenoid Hypertrophy?, Baran Acar, Hayri̇ye Karabulut, Mehmet Ali̇ Babademez, Selahatti̇n Genç, R. Murat Karaşen Jan 2009

Is The Traditional Treatment Approach Adequate In Children With Adenoid Hypertrophy?, Baran Acar, Hayri̇ye Karabulut, Mehmet Ali̇ Babademez, Selahatti̇n Genç, R. Murat Karaşen

Turkish Journal of Medical Sciences

Aim: We aimed to show the necessity of 1) endoscopic assessment after adenoidectomy performed blindly by adenoid curette, adenotome or adenoid punch forceps after checking adenoid size with finger palpation, which is commonly used in routine practice and 2) extraction of residual adenoids with additional methods. Materials and Methods: Prospective intraoperative flexible endoscopic evaluation of the nasopharynx in a case series of 51 patients was performed. The degree of residual postnasal obstruction due to adenoid tissue was assessed endoscopically with 2.7-mm 0° telescope (small, moderate, large) after routine transoral adenoidectomy. The telescope was then introduced transnasally, and residual adenoid tissue …


Correlation Between Calprotectin And Oxidized Ldl In Preeclampsia, Bünyami̇n Börekçi̇, Hülya Aksoy, Nuri̇nni̇sa Öztürk, Sedat Kadanali Jan 2009

Correlation Between Calprotectin And Oxidized Ldl In Preeclampsia, Bünyami̇n Börekçi̇, Hülya Aksoy, Nuri̇nni̇sa Öztürk, Sedat Kadanali

Turkish Journal of Medical Sciences

Aim: To evaluate the relationship between serum calprotectin and oxidized low density lipoprotein (LDL) in preeclamptic patients. Additionally, we aimed to measure serum malondialdehyde (MDA) levels as an oxidative stress marker. Materials and Methods: Serum calprotectin, oxidized LDL, and MDA levels were measured in a cross-sectional study of 61 preeclamptic patients (39 severe preeclampsia and 22 mild preeclampsia cases) and 20 healthy pregnant subjects. Serum MDA concentration was measured with spectrophotometric methods, and oxidized LDL and calprotectin were measured via enzyme-linked immunoassay (ELISA). Results: Serum calprotectin (P < 0.0001 and P = 0.014) and MDA (P = 0.001 and P = 0.028) levels were significantly higher in the severe and mild preeclampsia groups than in the healthy control group. Serum oxidized LDL concentration was slightly higher, but not did reach a statistically significant level, in the severe preeclampsia group than in the healthy pregnant group (P = 0.2). There was a significant negative correlation between the levels of calprotectin and oxidized LDL (r = -0.34, P = 0.006) in the mild and severe preeclampsia groups. The correlation between calprotectin and MDA was not statistically significant (P = 0.08). Conclusions: The findings suggest that increased calprotectin is associated with preeclampsia. Further study is necessary in order to determine whether or not high calprotectin levels prevent oxidation of circulating LDL in preeclampsia cases.


The Significance Of Dna Ploidy In The Malignant Potential Of Colorectal Adenocarcinomas, Ümi̇t Çobanoğlu, Hayretti̇n Çiray, Yavuz Tekeli̇oğlu, Yavuz Özoran, Etem Alhan Jan 2009

The Significance Of Dna Ploidy In The Malignant Potential Of Colorectal Adenocarcinomas, Ümi̇t Çobanoğlu, Hayretti̇n Çiray, Yavuz Tekeli̇oğlu, Yavuz Özoran, Etem Alhan

Turkish Journal of Medical Sciences

Aim: The aim of this study was to evaluate the association between flow cytometric DNA ploidy and the potential for invasiveness and lymph node metastasis in colorectal adenocarcinomas. Materials and Methods: The study included 40 colorectal carcinoma cases that were examined with flow cytometry and light microscopy. DNA ploidy in 4 different areas (deep tumor tissue, superficial tumor tissue, normal adjacent mucosa, and lymph node metastasis) was analyzed with flow cytometry and compared with invasiveness and lymph node metastasis Results: Statistically significant differences in DNA content were observed between the deep and superficial layers of tumor tissues. The rate of …


Necrosis In Human Cystic Echinococcosis: An Underrecognized Tissue Reaction Possibly Related To Host Response, Özlem Mi̇man, Meti̇n Atambay, Nasuhi̇ Engi̇n Aydin, Ni̇lgün Daldal Jan 2009

Necrosis In Human Cystic Echinococcosis: An Underrecognized Tissue Reaction Possibly Related To Host Response, Özlem Mi̇man, Meti̇n Atambay, Nasuhi̇ Engi̇n Aydin, Ni̇lgün Daldal

Turkish Journal of Medical Sciences

Aim: As Echinococcosis stands out worldwide as an important zoonotic cestode infection caused by various Echinococcus species, histopathological features of the disease are worthy of in-depth study. Materials and Methods: Histopathological changes in adjacent parenchymal tissue in patients with cystic echinococcosis (CE) were evaluated. The study included 91 patients 4-80 years of age (mean age: 36.24 years). Results: The histopathological findings of 83 specimens were as follows: fibrosis: 77.11%; mono-nucleated cells: 71.08%; necrosis: 67.47%; eosinophils: 51.80%; giant cells: 31.33%; neutrophils: 8.43%. Fibrosis, eosinophils, neutrophils, and giant cell infiltration were observed significantly more often than mono-nucleated cell infiltration, germinal membranes, and …


Risk Factors For Depression In Multiple Sclerosis Patients, Funda Kaplan, Mehmet Hami̇t Boztaş, Canan Yücesan, Yasemi̇n Genç, Nezi̇h Yücemen, Nermi̇n Mutluer Jan 2009

Risk Factors For Depression In Multiple Sclerosis Patients, Funda Kaplan, Mehmet Hami̇t Boztaş, Canan Yücesan, Yasemi̇n Genç, Nezi̇h Yücemen, Nermi̇n Mutluer

Turkish Journal of Medical Sciences

Aim: A search of the English language literature found only one study that reported there was no relationship between depression and functional systems impairment based on Kurtzke's functional systems score in MS patients. The present cross-sectional study was planned to test that result. Materials and Methods: The study included 37 relapsing-remitting MS patients (25 female, 12 male) with an Expanded Disability Status Scale score Keywords: Multiple sclerosis, depression, cerebellum