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Articles 3601 - 3630 of 4871
Full-Text Articles in Medicine and Health Sciences
Effect Of Essential Hypertension On Qtc Dispersion In Patients With Intracerebral Haemorrhage, Dursun Aygün, Bülent Şi̇şman, Mehmet Seli̇m Nural, Özcan Yilmaz, Ahmet Baydin
Effect Of Essential Hypertension On Qtc Dispersion In Patients With Intracerebral Haemorrhage, Dursun Aygün, Bülent Şi̇şman, Mehmet Seli̇m Nural, Özcan Yilmaz, Ahmet Baydin
Turkish Journal of Medical Sciences
To investigate the effects of essential hypertension on QTc dispersion (QTcd) in patients with intracerebral haematoma (ICH). Materials and methods: This prospective study included adult patients presenting with acute ICH within the first 24 h of ictus to the Emergency Department (ED). On admission, following the first clinical assessment of patients, a complete 12-lead ECG and non-contrast computed tomography (CT) were obtained from each patient. Then, the patients were divided into 2 subgroups according to the presence of hypertension history. The patient groups were compared to each other as well as the control group for QTcd. Results: The study groups …
Investigation Of Premenstrual Syndrome And Contributing Factors Among University Students*, Nülüfer Erbi̇l, Ayşenur Karaca, Tülay Kiriş
Investigation Of Premenstrual Syndrome And Contributing Factors Among University Students*, Nülüfer Erbi̇l, Ayşenur Karaca, Tülay Kiriş
Turkish Journal of Medical Sciences
To determine the frequency of premenstrual syndrome (PMS) and to investigate contributing factors for PMS among female students in a university dormitory in Ordu. Materials and methods: This descriptive study was conducted with female students at a public university dormitory in Ordu, in the East Black Sea region of Turkey. The sample contained 300 female students at the university dormitory. The study was conducted between 3 January and 12 January 2007. The research data were collected via a 22-item socio-demographic information questionnaire and the Premenstrual Syndrome Scale (PMSS) developed by Gençdoğan. Results: It was determined that the participants' mean age …
The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r
The Effect Of Microorganisms On Cytokine Secretion From Bone Marrow Dendritic Cells, Işil Fi̇dan, Ayşe Kalkanci, Emi̇ne Yeşi̇lyurt, Berna Erdal, Semra Kuşti̇mur, Turgut İmi̇r
Turkish Journal of Medical Sciences
Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens. They also contribute to the innate resistance against microbial pathogens. The present study examined the effect of microorganisms such as Escherichia coli (E. coli), Serratia marcescens (S. marcescens), Methicillin-resistant Staphylococcus aureus (MRSA), coagulase negative staphylococci (CoNS), and Candida albicans (C. albicans) on cytokine secretion in bone marrow-dendritic cells (BM-DCs). Materials and methods: The levels of cytokines in culture supernatants of the BM-DC were determined by enzyme-linked immunosorbent assay. Results: DCs stimulated by microorganisms produced large amounts of TNF-\alpha, IL-1\beta, IL-6, and IL-10. The …
Underestimated Role Of Alcohol At Skin Disinfection: Lipid Dissolving Property When Used In Association With Conventional Antiseptic Agents, Alp Yentür, İsmet Topçu, Ruşen Işik, Kenan Değerli̇, Süheyla Sürücüoğlu
Underestimated Role Of Alcohol At Skin Disinfection: Lipid Dissolving Property When Used In Association With Conventional Antiseptic Agents, Alp Yentür, İsmet Topçu, Ruşen Işik, Kenan Değerli̇, Süheyla Sürücüoğlu
Turkish Journal of Medical Sciences
After conventional aqueous disinfectant solutions, it was shown that microorganisms were still protected in hair follicles. We hypothesized that those aqueous disinfectant solutions when used in combination with alcohol may be more effective on the inhibition of recolonization of skin and therefore catheter tip colonization. Materials and methods: Skin surface samples were taken from epidural catheter insertion sites prior to catheterization, and before and after disinfection with different combinations of povidone-iodine, chlorhexidine, and alcohol. Before catheter removal, cultures were taken once more and tips of the catheters were cultured. Results: Catheter tip colonization and skin culture results of 10% povidone-iodine …
Comparative Efficacy Of Caffeic Acid Phenethyl Ester (Cape), Olopatadine Hydrochloride, And Dexamethasone Sodium Phosphate In Experimental Allergic Conjunctivitis*, Erdi̇nç Aydin, Heli̇n Deni̇z Demi̇r, Hüseyi̇n Özyurt, Ünal Erkorkmaz
Comparative Efficacy Of Caffeic Acid Phenethyl Ester (Cape), Olopatadine Hydrochloride, And Dexamethasone Sodium Phosphate In Experimental Allergic Conjunctivitis*, Erdi̇nç Aydin, Heli̇n Deni̇z Demi̇r, Hüseyi̇n Özyurt, Ünal Erkorkmaz
Turkish Journal of Medical Sciences
To compare the antiallergic efficacy of 1% caffeic acid phenethyl ester (CAPE), 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate. Materials and methods: Experimental allergic conjunctivitis was provoked by a mast cell activator (compound 48/80) in 31 New Zealand rabbits. The rabbits were divided into 3 groups, and 1% CAPE, 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate were instilled 30 min before and 15 min after the provocation. The edema and hyperemia in the experimental (right) eyes and control (left) eyes were scored in each group. Anterior segment photographs and conjunctival samples for histopathological evaluation and scoring were taken. …
Histopathological Effects Of Chronic Fluorosis On The Liver Of Mice (Swiss Albino), Yusuf Ersan, Evren Koç, İsmai̇l Ari, Başaran Karademi̇r
Histopathological Effects Of Chronic Fluorosis On The Liver Of Mice (Swiss Albino), Yusuf Ersan, Evren Koç, İsmai̇l Ari, Başaran Karademi̇r
Turkish Journal of Medical Sciences
Fluoride intake in high doses has toxic effects on various organs. Chronic fluorosis results in tubular degenerations, inflammation, fibrosis, parenchymatous nephritis, cloudy swellings, and dilations of convoluted tubules. In addition to these effects, fluoride causes deteriorative effects on the skeleton, teeth, and soft tissues. The goal of this study was to examine the impacts of chronic fluorosis on the liver tissues of mice. Materials and methods: One control group and 3 experimental groups, each group consisting of 4 male and 4 female mice, were formed to conduct the experiment. A stock solution including 2000 ppm fluoride was prepared by solving …
Effects Of Alendronate And Risedronate Therapy On Hepatic Antioxidant Enzyme Activity And Lipid Peroxidation In Ovariectomized Rats, Serap Yalin, Ülkü Çömelekoğlu, Selda Bağiş, Mehmet Berköz, Peli̇n Eroğlu
Effects Of Alendronate And Risedronate Therapy On Hepatic Antioxidant Enzyme Activity And Lipid Peroxidation In Ovariectomized Rats, Serap Yalin, Ülkü Çömelekoğlu, Selda Bağiş, Mehmet Berköz, Peli̇n Eroğlu
Turkish Journal of Medical Sciences
To evaluate the effects of alendronate (ALN) and risedronate (RIS), which are agents for preventing and treating postmenopausal osteoporosis, on hepatic antioxidant enzyme activity and lipid peroxidation in ovariectomized rats. Materials and methods: Thirty-two female rats were randomly assigned to 4 separate groups. All of the groups, except the control group, were ovariectomized. Included in the 4 groups were a control group (C), an ovariectomized group (OVX), an ovariectomized group treated with alendronate (OVX-ALN), and an ovariectomized group treated with risedronate (OVX-RIS). Ten weeks after an ovariectomy, the OVX-ALN rats were administered 1.75 mg/kg of their body weight with alendronate …
N-Acetyltransferase 2 Gene Polymorphisms And Susceptibility To Prostate Cancer: A Pilot Study In The Turkish Population, Buket Kosova, Vi̇ldan Bozok Çeti̇ntaş, Ahmet Çağ Çal, Asli Teti̇k, Ruki̇ye Özel, Çağdaş Aktan, Cumhur Gündüz, Nejat Topçuoğlu, İbrahi̇m Kadri̇ Cürekli̇batir, Fatma Zuhal Eroğlu
N-Acetyltransferase 2 Gene Polymorphisms And Susceptibility To Prostate Cancer: A Pilot Study In The Turkish Population, Buket Kosova, Vi̇ldan Bozok Çeti̇ntaş, Ahmet Çağ Çal, Asli Teti̇k, Ruki̇ye Özel, Çağdaş Aktan, Cumhur Gündüz, Nejat Topçuoğlu, İbrahi̇m Kadri̇ Cürekli̇batir, Fatma Zuhal Eroğlu
Turkish Journal of Medical Sciences
To investigate the association between the 3 most frequently observed single nucleotide polymorphisms of the NAT2 gene and the risk of developing prostate cancer in the Turkish population. Materials and methods: A total of 110 unrelated patients with prostate cancer were included in this case-control association study and constituted the study group. The control group also consisted of 150 unrelated but healthy men. Genomic DNA was isolated from peripheral blood leukocytes of all patients and analyzed with a sensitive real-time PCR method. After melting curve analysis genotypes were identified for the NAT2*5A, NAT2*6A, and NAT2*7A/B polymorphisms. Results: Prostate cancer patients …
Absence Of Vancomycin-Resistant Enterococci (Vre) Despite The Presence Of Risk Factors: A Survey Of Rectal Carriage Of Vre*, Zeli̇ha Koçak Tufan, Selcan Arslan, Sali̇h Cesur, Cemal Bulut, Hasan Irmak, Sami̇ Kinikli, Ferah Ergi̇n, Ali̇ Kutta Çeli̇k, Ali̇ Pekcan Demi̇röz
Absence Of Vancomycin-Resistant Enterococci (Vre) Despite The Presence Of Risk Factors: A Survey Of Rectal Carriage Of Vre*, Zeli̇ha Koçak Tufan, Selcan Arslan, Sali̇h Cesur, Cemal Bulut, Hasan Irmak, Sami̇ Kinikli, Ferah Ergi̇n, Ali̇ Kutta Çeli̇k, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
The resistant organisms from patients and healthcare workers (HCWs) first colonized the gastrointestinal tract before causing infections in patients. In this study, presence of risk factors for vancomycin-resistant enterococci (VRE) colonization and the prevalence of rectal carriage of VRE among HCWs and hospitalized patients in the absence of an outbreak were investigated. Design: Cross-sectional study. Setting: A 600-bed training and research hospital. Materials and methods: A total of 508 intensive-care unit (ICU) patients and HCWs in these units were included. Risk factors such as previous antibiotic use, especially vancomycin and cephalosporin, the presence of invasive devices like catheters, and co-morbid …
Pulmonary Hydatid Disease In Southeastern Anatolia, Turkey, Selver Özeki̇nci̇, Şule Bakir, Ali̇ Kemal Uzunlar, Şevval Eren
Pulmonary Hydatid Disease In Southeastern Anatolia, Turkey, Selver Özeki̇nci̇, Şule Bakir, Ali̇ Kemal Uzunlar, Şevval Eren
Turkish Journal of Medical Sciences
To evaluate retrospectively epidemiological parameters and clinicopathologic figures of pulmonary hydatid disease in our region. Materials and methods: A total of 117 cases of human pulmonary hydatid disease were included in this study, and these cases were diagnosed in the Department of Pathology of Dicle University Medical School, between 1987 and 2007. The patients' data were retrospectively collected from archival reports; in addition, some of the patients were still alive and contactable. Results: Our 117 cases consisted of 66 (56.41%) females and 51 (43.58%) males. The average age was 28.18. Pulmonary hydatidosis appears to be more common in younger individuals. …
Thyroid Hormone Reference Intervals And The Prevalence Of Thyroid Antibodies, Aydan Çelebi̇ler, Si̇bel Bi̇lgi̇li̇, Emi̇ne Ömür Erkizan, Huri̇ye Seri̇n, Muhammet Baysal Karaca
Thyroid Hormone Reference Intervals And The Prevalence Of Thyroid Antibodies, Aydan Çelebi̇ler, Si̇bel Bi̇lgi̇li̇, Emi̇ne Ömür Erkizan, Huri̇ye Seri̇n, Muhammet Baysal Karaca
Turkish Journal of Medical Sciences
To establish new reference intervals for thyrotropin (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) on the Beckman Coulter DxI 800 in healthy Turkish adults and assess the prevalence of laboratory evidence of thyroid antibodies in this population. Materials and methods: Specimens were obtained from 619 healthy volunteers (338 females, 281 males).The study was conducted with health care professionals and their relatives, The mean age of all the subjects was 34.7 and the median was 31 years, with ages ranging from 15 to 84. Moreover, the subjects had no evidence of thyroid autoimmunity or a history of drug use, both …
Letter To The Editor, Di̇lşen Çolak, Arzu Akşahi̇n, Mustafa Altinbaş
Letter To The Editor, Di̇lşen Çolak, Arzu Akşahi̇n, Mustafa Altinbaş
Turkish Journal of Medical Sciences
No abstract provided.
Prediction Of Prostate Cancer Using Decision Tree Algorithm, Kemal Hakan Gülkesen, İsmai̇l Türker Köksal, Sebahat Özdem, Osman Saka
Prediction Of Prostate Cancer Using Decision Tree Algorithm, Kemal Hakan Gülkesen, İsmai̇l Türker Köksal, Sebahat Özdem, Osman Saka
Turkish Journal of Medical Sciences
Serum Prostate Specific Antigen (PSA) level is used for prediction of cancer, but this approach suffers from weak sensitivity and specificity. We applied binary-split decision tree (DT) algorithm to prostate cancer prediction problem. Materials and methods: Quick, Unbiased and Efficient Statistical Tree (QUEST) algorithm was used in 750 patients who had a serum PSA levels between 0 and 10 ng/mL. Results: The analysis indicated that following five nodes had different levels of cancer possibility: (1) PSA > 5.98 ng/mL; (2) PSA 0.81; (4) PSA Keywords:
Serum Adenosine Deaminase Activity And The Total Antioxidant Capacity Of Plasma In Pulmonary Tuberculosis And Non-Tuberculosis Pulmonary Disease, Mohammad Naderi, Mohammad Hashemi, Ali Mehdizadeh, Hamid Mehrabifar, Hamid Reza Kouhpayeh, Hossein Ansari, Gholamreza Bahari, Saeid Ghavami
Serum Adenosine Deaminase Activity And The Total Antioxidant Capacity Of Plasma In Pulmonary Tuberculosis And Non-Tuberculosis Pulmonary Disease, Mohammad Naderi, Mohammad Hashemi, Ali Mehdizadeh, Hamid Mehrabifar, Hamid Reza Kouhpayeh, Hossein Ansari, Gholamreza Bahari, Saeid Ghavami
Turkish Journal of Medical Sciences
The aim of this study was to investigate the level of serum adenosine deaminase (ADA) and the total antioxidant capacity (TAC) in pulmonary tuberculosis (PTB), non-tuberculosis pulmonary disease (non-PTB) and healthy subjects. Materials and methods: Serum ADA activity was measured using the Giusti and Galanti method, and the total antioxidant capacity of plasma was determined by the ferric reducing ability of plasma (FRAP) test. Results: The serum ADA levels were significantly higher (P < 0.001) in pulmonary TB (PTB, 19.78 ± 7.09 U/L), as well as in non-PTB patients (14.78 ± 4.65 U/L) when compared to healthy controls (10.02 ± 1.99 U/L). The sensitivity and specificity were found to be 71.7% and 63.3%, respectively, in distinguishing PTB from non-PTB. In distinguishing PTB from healthy subjects, the sensitivity and specificity were 87% and 93.3%, respectively. The TAC was significantly lower in PTB (485.2 ± 190.0 µM) and non-PTB patients (588.3 ± 195.8 µM), when compared to the controls (784.3 ± 190.0 µM; P < 0.001). Plasma antioxidative activity decreased in PTB and non-PTB patients when compared to the controls. Conclusion: We concluded that serum ADA activity is not a useful test to differentiate pulmonary TB from other respiratory diseases. The TAC is low in pulmonary TB, therefore supplementation with a suitable anti-oxidant may be useful.
Chronic Pain And Depression: A Descriptive Survey Among Adult Primary Health Care Centre Patients, Nüket Paksoy Erbaydar, Nesri̇n Çi̇li̇ngi̇roğlu
Chronic Pain And Depression: A Descriptive Survey Among Adult Primary Health Care Centre Patients, Nüket Paksoy Erbaydar, Nesri̇n Çi̇li̇ngi̇roğlu
Turkish Journal of Medical Sciences
Knowledge of chronic pain and its relationship to depression among primary health care patients in Turkey is inadequate. The aim of this study was to evaluate the frequency of chronic pain and its relationship to depression. Materials and methods: In this descriptive study, data was collected with a questionnaire based on sociodemographic and pain-related characteristics, which was administered to a study population (n = 259) of primary care patients, 18-64 years old. The Visual Analogue Scale (VAS) (min-max = 0-10) and Beck Depression Inventory (BDI) (min-max = 0-63) were used for the assessment of pain severity and depression. Results: Of …
Effects Of Vitamin A And C And Melatonin On 3-Nitrotyrosine Formation In Guinea Pig Heart Under Lipopolysaccharide-Induced Stress, Hali̇l Yaman, Tuncer Çayci, Meli̇k Seyrek, Emi̇n Özgür Akgül, Yasemi̇n Gülcan Kurt, İbrahi̇m Aydin, Hakan Yaren, Erdi̇nç Çakir, Ömer Özcan, Behzat Çi̇men, Nurten Türközkan, Mehmet Kemal Erbi̇l
Effects Of Vitamin A And C And Melatonin On 3-Nitrotyrosine Formation In Guinea Pig Heart Under Lipopolysaccharide-Induced Stress, Hali̇l Yaman, Tuncer Çayci, Meli̇k Seyrek, Emi̇n Özgür Akgül, Yasemi̇n Gülcan Kurt, İbrahi̇m Aydin, Hakan Yaren, Erdi̇nç Çakir, Ömer Özcan, Behzat Çi̇men, Nurten Türközkan, Mehmet Kemal Erbi̇l
Turkish Journal of Medical Sciences
Bacterial lipopolysaccharide (LPS) triggers synthesis of nitric oxide (NO) and superoxide (O_2^{.-}). O_2^{.-} can react with NO to produce the powerful oxidant peroxynitrite (ONOO-). The presence of 3-nitrotyrosine (3-NT) in tissues is often used as a marker of ONOO- production. Vitamin A, vitamin C, and melatonin are potent antioxidant molecules. We sought to clarify this issue by examining the effects of vitamin A (15,000 IU/kg/day), vitamin C (600 mg/kg/day), and melatonin (25 mg/kg) on 3-NT formation in heart tissue in a guinea pig model of LPS-induced endotoxemia. Materials and methods: A total of 75 animals were randomly divided into 5 …
Penile Mondor's Disease Can Be Effectively Treated With The Use Of An Acetyl Salicylic Acid And Pentoxifylline Combination, Mürsel Davarci, Eşref Oğuz Güven, Ahmet Gökçe, Fati̇h Rüştü Yalçinkaya, Ahmet Namik Ki̇per, Mevlana Derya Balbay
Penile Mondor's Disease Can Be Effectively Treated With The Use Of An Acetyl Salicylic Acid And Pentoxifylline Combination, Mürsel Davarci, Eşref Oğuz Güven, Ahmet Gökçe, Fati̇h Rüştü Yalçinkaya, Ahmet Namik Ki̇per, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
Since penile Mondor's disease is a rare condition, different treatment choices are used. Herein we recommend a new treatment strategy with acetylsalicylic acid and pentoxifylline, which was tested in 14 patients with penile Mondor's disease. Materials and methods: Fourteen patients with the clinical presentation of penile Mondor's disease were included. Patients were given acetylsalicylic acid (ASA) 500 mg qid and pentoxifylline 600 mg bid for 14 days. Physical examinations were performed in all patients. In addition, ultrasonic examinations were done before the treatment and on days 7 and 14 of treatment to evaluate dorsal vein thrombosis. Results: Physical examinations revealed …
Dissection Of Mesoappendix In Laparoscopic Appendectomy: A Comparison Of Monopolar Cautery And Bipolar Vessel Sealing System, Emrah Şenel, Fati̇h Akbiyik, Hali̇l Faruk Atayurt, Hüseyi̇n Tuğrul Ti̇ryaki̇
Dissection Of Mesoappendix In Laparoscopic Appendectomy: A Comparison Of Monopolar Cautery And Bipolar Vessel Sealing System, Emrah Şenel, Fati̇h Akbiyik, Hali̇l Faruk Atayurt, Hüseyi̇n Tuğrul Ti̇ryaki̇
Turkish Journal of Medical Sciences
Various technique and different instruments like endoscopic stapler, endoscopic clip, monopolar cautery, harmonic scalpel, and bipolar vessel sealer can be used in the dissection of appendix mesentery when performing laparoscopic appendectomy. The aim of this study is to evaluate the effects of using monopolar cautery and bipolar vascular sealing instruments in the dissection of mesentery of appendix on the duration of the operation of pediatric patients. Materials and methods: Sixty three patients, operated laparoscopically for acute appendicitis in between June 2008 and June 2009 at the Pediatric Surgery Clinic of Dışkapı Children's Hospital, are evaluated retrospectively. Monopolar cautery was used …
Comparative Effects Of Levosimendan And Dobutamine Infusion On P Wave Dispersion In Patients With Acute Decompensated Heart Failure, Ati̇la İyi̇soy, Turgay Çeli̇k, Murat Çeli̇k, Bariş Buğan, Hali̇l Yaman
Comparative Effects Of Levosimendan And Dobutamine Infusion On P Wave Dispersion In Patients With Acute Decompensated Heart Failure, Ati̇la İyi̇soy, Turgay Çeli̇k, Murat Çeli̇k, Bariş Buğan, Hali̇l Yaman
Turkish Journal of Medical Sciences
We aimed to evaluate the comparative effects of levosimendan and dobutamine on P-wave dispersion (PWD) in the patients with acute decompensated heart failure (ADHF). Materials and methods: The study population consisted of 40 patients (mean age = 68 years, 23 men, NYHA class III-IV) presented with ADHF. Patients were randomized to intravenous levosimendan (n = 20) or dobutamine (n = 20) groups. The P-wave duration measurements were calculated in 12-lead surface ECG simultaneously and recorded before and after treatment. Manual measurements of P-wave duration were performed with digital calipers on a high resolution computer screen by two cardiologists not aware …
Prevalence Of Anaemia In Women Of Reproductive Age In Meghalaya: A Logistic Regression Analysis, Sanku Dey, Sankar Goswami, Madhuchhanda Goswami
Prevalence Of Anaemia In Women Of Reproductive Age In Meghalaya: A Logistic Regression Analysis, Sanku Dey, Sankar Goswami, Madhuchhanda Goswami
Turkish Journal of Medical Sciences
To examine the prevalence of anaemia in Meghalaya, India, by exploring the 2005-2006 National Family Health Survey (NFHS -3) data. Materials and methods: The study population consisted of 3934 ever-married women of reproductive age (15-49 years) from the state Meghalaya, India, which were taken from the NFHS-3 survey, to explore the predictors responsible for the prevalence of anaemia by using different background characteristics such as age, place of residence, nutritional status, number of children ever born, pregnancy status, educational achievement, and economic status. As a response variable, anaemia levels were categorised as a dichotomous variable, and the predicted probabilities were …
Restricted Universal Guidelines For Rop Screening: A Possible Misguidance For Middle Income Countries, Ömer Erdeve, Begüm Atasay, Saadet Arsan, Fi̇gen Batuoğlu, Huban Ati̇lla, Tomri̇s Türmen
Restricted Universal Guidelines For Rop Screening: A Possible Misguidance For Middle Income Countries, Ömer Erdeve, Begüm Atasay, Saadet Arsan, Fi̇gen Batuoğlu, Huban Ati̇lla, Tomri̇s Türmen
Turkish Journal of Medical Sciences
The objective of all studies evaluating retinopathy of prematurity (ROP) screening criteria has been to minimize the number of infants screened while missing no patients with ROP who required treatment. Studies supporting the recommendation that screening for ROP could be restricted to infants born at less than 30 weeks of gestation with birth weights of less than 1250 g have been reported recently, especially from Western countries. However, with the lack of local outcome data, application of the new restricted screening guidelines to infants in middle income countries may lead to misguidance. We aimed to investigate ROP screening requirements in …
Feminizing Genitoplasty: An Evaluation Of 41 Patients In 8 Years, Fati̇h Akbiyik, Hüseyi̇n Tuğrul Ti̇ryaki̇, Emrah Şenel, Ervi̇n Mambet, Yusuf Zi̇ya Li̇vaneli̇oğlu, Hali̇l Faruk Atayurt
Feminizing Genitoplasty: An Evaluation Of 41 Patients In 8 Years, Fati̇h Akbiyik, Hüseyi̇n Tuğrul Ti̇ryaki̇, Emrah Şenel, Ervi̇n Mambet, Yusuf Zi̇ya Li̇vaneli̇oğlu, Hali̇l Faruk Atayurt
Turkish Journal of Medical Sciences
The authors present early results of feminizing genitoplasty procedures. Materials and methods: Medical records of 41 patients who underwent feminizing genitoplasty in between 2001 and 2009 were evaluated retrospectively. Results: Follow-up period was 1 month to 7.5 years. Clitorolabial cosmesis was good in all patients except one. Neither clitoral necrosis nor enlargement was noted in postoperative period. The most common complication observed was vaginal stenosis. For 7 patients with severe stenosis, reoperations are planned at puberty. Conclusion: One-stage or staged genitoplasty is performed for disorders of sexual development (DSD) patients. Although results of clitoroplasty are satisfactory, reoperation rates due to …
Two Siblings With Netherton Syndrome, Selma Emre, Ahmet Meti̇n, D. Deni̇z Demi̇rseren, Ahu Yorulmaz, Aykut Onursever, Burçi̇n Kaftan
Two Siblings With Netherton Syndrome, Selma Emre, Ahmet Meti̇n, D. Deni̇z Demi̇rseren, Ahu Yorulmaz, Aykut Onursever, Burçi̇n Kaftan
Turkish Journal of Medical Sciences
Netherton syndrome (NS) is a rare genodermatosis characterized by autosomal recessive inheritance pattern, unknown etiology, ichthyosiform cutaneous changes, atopic diathesis, and alterations in the hair shaft. As a result of aging coupled with immune deficiency, clinical symptoms may vary. Herein, we present 2 siblings with the characteristic cutaneous symptoms of NS, albeit with some differences between the siblings. Materials and methods: Two sisters presented to our clinic with sparse and brittle hair along with pruritic, erythematous, and scaling cutaneous lesions. Both patients underwent a clinical examination and laboratory analyses. Results: Based on the clinical and laboratory findings, both patients were …
Gastric Volvulus Due To Diaphragmatic Eventration And Paraesophageal Hernia, Nuretti̇n Özgür Doğan, Gökhan Aksel, Ahmet Demi̇rcan, Ayfer Keleş, Fi̇kret Bi̇ldi̇k
Gastric Volvulus Due To Diaphragmatic Eventration And Paraesophageal Hernia, Nuretti̇n Özgür Doğan, Gökhan Aksel, Ahmet Demi̇rcan, Ayfer Keleş, Fi̇kret Bi̇ldi̇k
Turkish Journal of Medical Sciences
Acute gastric volvulus occurs when the stomach or a part of it rotates more than 180 degrees. It is a potentially life-threatening entity and most cases of gastric volvulus occur in association with eventration of left hemidiaphragm or a hiatal hernia. Gastric volvulus is a rare condition and presents with nonspecific epigastric pain and vomiting, and therefore may be missed. Chest x-ray and CT can help the diagnosis. Emergent surgical approach is mandatory. Two elderly patients admitted to ED with epigastric pain and intractable vomiting did not respond to the treatment and we were not able to pass nasogastric tube. …
Incidence And Risk Factors For Bloodstream Infections Stemming From Temporary Hemodialysis Catheters, Hati̇ce Rahmet Çaylan, Gürdal Yilmaz, Ebru Emel Sözen, Kemaletti̇n Aydin, İftahar Köksal
Incidence And Risk Factors For Bloodstream Infections Stemming From Temporary Hemodialysis Catheters, Hati̇ce Rahmet Çaylan, Gürdal Yilmaz, Ebru Emel Sözen, Kemaletti̇n Aydin, İftahar Köksal
Turkish Journal of Medical Sciences
Catheter-related bloodstream infection (CR-BSI) is considered as an important complication of hemodialysis catheters. The purpose of this prospective study was to evaluate the incidence and risk factors of temporary hemodialysis catheter-related bloodstream infection. Materials and methods: Prospective data related to temporary hemodialysis catheters inserted in our institution were collected for duration of three years. The risk factors of CR-BSI of patients between the CR-BSI group and the control group were compared. Results: A total of 248 temporary hemodialysis catheters were inserted in 201 patients and remained in situ for a cumulative total of 5192 catheter days. There were 3254 dialysis …
Prevalence Of Cardiac Arrhythmia In Obstructive Sleep Apnea Syndrome, Ni̇hal Akar Bayram, Bülent Çi̇ftçi̇, Selma Firat Güven, Hüseyi̇n Bayram, Hasbi̇ Erdem Di̇ker, Tahi̇r Durmaz, Telat Keleş, Engi̇n Bozkurt
Prevalence Of Cardiac Arrhythmia In Obstructive Sleep Apnea Syndrome, Ni̇hal Akar Bayram, Bülent Çi̇ftçi̇, Selma Firat Güven, Hüseyi̇n Bayram, Hasbi̇ Erdem Di̇ker, Tahi̇r Durmaz, Telat Keleş, Engi̇n Bozkurt
Turkish Journal of Medical Sciences
Repetitive transient activation of the parasympathetic and sympathetic systems in obstructive sleep apnea syndrome (OSAS) constitutes the basis for development of cardiac arrhythmias. We aimed to examine the prevalence of arrhythmias in OSAS. Materials and methods: Eighty-eight patients with suspected OSAS were included in the study. Polysomnography was performed overnight in all patients. Patients with apnea-hypopnea index (AHI) < 5 were considered OSAS negative, while patients with AHI >= 5 were OSAS positive. Arrhythmia was defined as sinus bradycardia, sinus tachycardia, > 10/h supraventricular premature beats (SVPBs), > 10/h ventricular premature beats (VEBs), complex VPBs (bigeminal, trigeminal VEB or nonsustained VT), supraventricular tachycardia, ventricular tachycardia, > 2 s sinus arrest, second or third …
Predisposing Factors For Serum Sodium Disturbance In Patients With Severe Traumatic Brain Injury (Sbi), Mohammadreza Safavi, Saied Abrishamkar, Poria Tvakoli, Daruosh Moradi, Azim Honarmand
Predisposing Factors For Serum Sodium Disturbance In Patients With Severe Traumatic Brain Injury (Sbi), Mohammadreza Safavi, Saied Abrishamkar, Poria Tvakoli, Daruosh Moradi, Azim Honarmand
Turkish Journal of Medical Sciences
Disturbances in the plasma sodium level in patients with severe brain injury (SBI) is not a rare phenomenon and may cause adverse effects on prognosis and treatment outcomes. The knowledge of the prevalence of risk factors helps in early detection and good management of the serum sodium level disturbance. Materials and methods: This is a prospective clinical trial double blind study. The target population included patients with SBI who had disturbances in their plasma sodium level and were admitted at the ICU of Kashani Hospital, Isfahan, Iran, between January and October 2006. The patients with renal insufficiency, diuretic therapy, massive …
The Association Of Tafi (Thrombin-Activatable Fibrinolysis Inhibitor) With Insulin Resistance And Components Of Metabolic Syndrome In Patients With Metabolic Syndrome, Alev Kural, Ahmet Omma, Hati̇ce Seval, Maci̇t Koldaş, Namik Yi̇ği̇t, Tülay Omma
The Association Of Tafi (Thrombin-Activatable Fibrinolysis Inhibitor) With Insulin Resistance And Components Of Metabolic Syndrome In Patients With Metabolic Syndrome, Alev Kural, Ahmet Omma, Hati̇ce Seval, Maci̇t Koldaş, Namik Yi̇ği̇t, Tülay Omma
Turkish Journal of Medical Sciences
To investigate the association of TAFI with components of metabolic syndrome and insulin resistance in patients with metabolic syndrome. Materials and methods: Patients between 20 and 70 years of age, who met at least 3 of the metabolic syndrome criteria, and had no known coronary artery disease were included in the study. The control group consisted of 20 healthy subjects with demographic characteristics similar to the patients. Fasting blood glucose, HbA1c, lipid profile, insulin, microalbumin, and TAFI Ag levels were investigated in the patients and controls. Insulin resistance was calculated according to the HOMA-IR [(fasting plasma insulin (\muIU/ml) x fasting …
Vitamin C Modulates Oxidative Stress-Induced Colitis In Rats, Mustafa Zeri̇n, Ali̇ Zi̇ya Karakilçik, Muharrem Bi̇ti̇ren, Davut Musa, Abdullah Özgönül, Şehabetti̇n Selek, Yaşar Nazligül, Ali̇ Uzunköy
Vitamin C Modulates Oxidative Stress-Induced Colitis In Rats, Mustafa Zeri̇n, Ali̇ Zi̇ya Karakilçik, Muharrem Bi̇ti̇ren, Davut Musa, Abdullah Özgönül, Şehabetti̇n Selek, Yaşar Nazligül, Ali̇ Uzunköy
Turkish Journal of Medical Sciences
Free radicals are an important factor in the etiopathogenesis of colitis and may increase oxidative damage. The antioxidant vitamin C efficiently scavenges free oxygen radicals. The present study aimed to investigate the probable protective effects of vitamin C on oxidative injury in rats in which colitis was experimentally induced with acetic acid. Materials and methods: This study was conducted with rats for a period of 7 days. Group 1 intrarectally received a placebo (0.9% NaCl) and group 2 intrarectally received 2 mL of 5% acetic acid (AA) and the placebo. Group 3 intrarectally received 2 mL of 5% AA and …
Evaluation Of Oxidant/Antioxidant Status And Ecp Levels In Asthma, Ömer Emecen, Berri̇n Berçi̇k İnal, Füsun Erdenen, Murat Usta, Hale Aral, Güvenç Güvenen
Evaluation Of Oxidant/Antioxidant Status And Ecp Levels In Asthma, Ömer Emecen, Berri̇n Berçi̇k İnal, Füsun Erdenen, Murat Usta, Hale Aral, Güvenç Güvenen
Turkish Journal of Medical Sciences
Inflammatory and immune cells, such as eosinophils, macrophages, and neutrophils, generate more reactive oxygen species in patients with asthma than they do in healthy individuals, and oxygen radicals contribute to tissue injury in asthma. We aimed to measure total oxidant status (TOS) and antioxidant status (TAS) in order to assess oxidative and antioxidative capacity. Eosinophil cationic protein (ECP), total IgE, and eosinophils (%) were measured to evaluate the level of inflammation. Materials and methods: The study included 56 non-smoking asthma patients that were followed-up at the respiratory disease and allergy outpatient clinics, where they received ongoing treatment for 5 months …