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Articles 3421 - 3450 of 4871
Full-Text Articles in Medicine and Health Sciences
Plasma Ldl Subtype Distribution In Patients With Or Without Coronary Stenosis, Yeşi̇m Er Öztaş, Çağdaş Özdöl, Levent Karaca
Plasma Ldl Subtype Distribution In Patients With Or Without Coronary Stenosis, Yeşi̇m Er Öztaş, Çağdaş Özdöl, Levent Karaca
Turkish Journal of Medical Sciences
Plasma low density lipoprotein (LDL) had 3 subtypes according to its separation by polyacrylamide gradient gel electrophoresis. Of these, the small, dense (Sd) LDL particles have been accepted as an emerging cardiovascular risk factor. This study was conducted to assess the LDL subtypes in a group of patients undergoing coronary angiography. Materials and methods: The study involved 56 patients—36 of whom had at least 1 vessel stenosed (stenosis group)—and 20 patients who had no stenosis (non-stenosis group). LDL subtypes were determined according to their migration pattern after non-denaturing gradient gel electrophoresis. Total cholesterol, LDL and high density lipoprotein (HDL), and …
Hydatid Cyst Viability: The Effect Of Scolicidal Agents On The Scolex In The Daughter Cyst, Mustafa Karaoğlanoğlu, Ömer Faruk Akinci, Mustafa Ulukanligi̇l, Meli̇ke Ruşen Meti̇n, Hüseyi̇n Çeti̇n, Nurdan Çay
Hydatid Cyst Viability: The Effect Of Scolicidal Agents On The Scolex In The Daughter Cyst, Mustafa Karaoğlanoğlu, Ömer Faruk Akinci, Mustafa Ulukanligi̇l, Meli̇ke Ruşen Meti̇n, Hüseyi̇n Çeti̇n, Nurdan Çay
Turkish Journal of Medical Sciences
To perform an in vitro study of the effects of various scolicidal agents on scolices in both crystal-clear fluid and daughter cysts. Materials and methods: A 2-staged procedure, using 15% NaCl, 3% NaCl, Betadine, 1% NaOCl, and alcohol, was performed on the cysts. Into bottles containing 10 cysts, 20 mL of each agent, including crystal-clear fluid, was added. A single daughter cyst was then taken from the bottles after 5, 10, 15, 20, 40, 60, and 120 min and the injected samples were examined microscopically for viability using activity and eosin staining. In the second stage of the study, the …
An Investigation Of Changes In Ocular Blood Flow In Rabbits With Long-Term Hyperhomocysteinemia Using Color Doppler Ultrasonography, Fi̇gen Nari̇n, Abdulhaki̇m Coşkun, Nazmi̇ Nari̇n, Ali̇ Baykan, Sertaç Hanedan Onan, Abdulkeri̇m Coşkun, Muammer Hakan Poyrazoğlu, Ruşen Erez
An Investigation Of Changes In Ocular Blood Flow In Rabbits With Long-Term Hyperhomocysteinemia Using Color Doppler Ultrasonography, Fi̇gen Nari̇n, Abdulhaki̇m Coşkun, Nazmi̇ Nari̇n, Ali̇ Baykan, Sertaç Hanedan Onan, Abdulkeri̇m Coşkun, Muammer Hakan Poyrazoğlu, Ruşen Erez
Turkish Journal of Medical Sciences
Hyperhomocysteinemia was induced in rabbits using methionine. Ocular blood flow changes were examined by color Doppler ultrasonography (CDU). Materials and methods: Fifty New Zealand rabbits were divided into 5 groups. Groups 1-4 received one of the following chemicals: methionine only, methionine plus vitamin B6, methionine plus vitamin B12, or methionine plus folic acid. Controls received no chemicals. Serum homocysteine levels were measured on treatment days 1 and 60. Orbital vessels were examined by CDU on day 60. Results: In the 4 study groups, homocysteine levels were significantly elevated on day 60 compared to the levels on day 1 (P < 0.05). Elevations of homocysteine levels in group 1 were greater than those of groups 2 and 4 on day 60 (P < 0.05). When results of ocular blood flow changes were compared, no statistically significant difference was found based on flow velocities in the ophthalmic artery. Measurements from the ciliary artery revealed a statistically significant decrease in flow velocity in the study groups (P < 0.05). Conclusion: Using CDU, we found that flow velocities in the ciliary artery were decreased. This condition is attributed to atherosclerotic and thromboembolic alterations of the ocular vessels due to hyperhomocysteinemia.
Histological Changes In The Healing Process Of Sclerotomy Sites After 20-Gauge And Transconjunctival 23- And 25-Gauge Incisions In Experimental Model*, Ni̇lüfer Koçak, Banu Lebe, Özlem Barut Selver, Mehmet Özgür Zengi̇n, Süleyman Kaynak
Histological Changes In The Healing Process Of Sclerotomy Sites After 20-Gauge And Transconjunctival 23- And 25-Gauge Incisions In Experimental Model*, Ni̇lüfer Koçak, Banu Lebe, Özlem Barut Selver, Mehmet Özgür Zengi̇n, Süleyman Kaynak
Turkish Journal of Medical Sciences
To evaluate the healing mechanism and histological changes of the 20-gauge standard, and 23- and 25-gauge transconjunctival sutureless vitrectomy (TSV) incisions in rabbits. Materials and methods: Twelve of 16 albino rabbits’ right eyes underwent sclerotomy of either 20-gauge standard, or 23-gauge or 25-gauge TSV incisions. Four rabbits were tested as controls. The study eyes were examined clinically on the first postoperative day and in 3-day periods for 2 weeks. After 2 weeks, rabbits were euthanized; globes were enucleated and underwent histological examination. The sclerotomy sites were investigated histopathologically under light microscope for wound healing semicantitatively. Results: Pathological sections were examined …
Protective Activity Of The Methanol Extract Of Usnea Longissima Against Oxidative Damage And Genotoxicity Caused By Aflatoxin B_1 In Vitro, Güleray Ağar, Ali̇ Aslan, Eli̇f Kotan Sarioğlu, Lokman Alpsoy, Selçuk Çeker
Protective Activity Of The Methanol Extract Of Usnea Longissima Against Oxidative Damage And Genotoxicity Caused By Aflatoxin B_1 In Vitro, Güleray Ağar, Ali̇ Aslan, Eli̇f Kotan Sarioğlu, Lokman Alpsoy, Selçuk Çeker
Turkish Journal of Medical Sciences
To investigate the effects of methanol extracts obtained from Usnea longissima (UME) on the genotoxicity and oxidative stress of aflatoxin B_1 (AFB_1) in cultured human blood cells. Materials and methods: Sister chromatid exchange (SCE) and micronucleus (MN) tests were used for estimation of genotoxic influences. Activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) and the malondialdehyde (MDA) level were also measured to evaluate the antioxidative effect of UME. Results: In the SCE and MN test systems, it was observed that UME suppressed the mutagenic effects of AFB_1. Furthermore, an increase of MDA level and a decrease of SOD and …
Retrospective Review Of Critically Ill Obstetrical Patients: A Decade's Experience, Tuncer Şi̇mşek, Can Eyi̇gör, Mehmet Uyar, Semra Karaman, Ali̇ Reşat Moral
Retrospective Review Of Critically Ill Obstetrical Patients: A Decade's Experience, Tuncer Şi̇mşek, Can Eyi̇gör, Mehmet Uyar, Semra Karaman, Ali̇ Reşat Moral
Turkish Journal of Medical Sciences
To investigate the reasons for the admission of obstetrical patients to the intensive care unit (ICU) and their clinical outcomes, to compare the roles of the current scoring systems in estimating the mortality of these patients, and to determine adverse prognostic factors in critically ill obstetrical patients. Materials and methods: Data were retrospectively obtained from obstetrical patients admitted to the ICU in our institution between January 1999 and April 2009. Demographic characteristics, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, Sequential Organ Failure Assessment (SOFA) score, and Glasgow Coma Scale (GCS) score of patients at the time of …
Documentation Of Small Intestine Atresias: A Single-Institution Experience In Turkey (22 Cases), Naci̇ye Ümi̇t Bayol, Demet Eti̇t, Süheyla Cumurcu, Deni̇z Altinel, Fatma Nur Aktaş, Rafet Beyhan
Documentation Of Small Intestine Atresias: A Single-Institution Experience In Turkey (22 Cases), Naci̇ye Ümi̇t Bayol, Demet Eti̇t, Süheyla Cumurcu, Deni̇z Altinel, Fatma Nur Aktaş, Rafet Beyhan
Turkish Journal of Medical Sciences
To investigate the associated anomalies and causes of death in a neonatal autopsy series with intestinal atresias over an 8-year period from the archives of our department. Intestinal atresia, meaning the complete absence of a segment of the intestine or complete occlusion of the intestinal lumen, is the most common cause of gastrointestinal obstruction in neonatal autopsy series. There is an approximately equal sex distribution. Materials and methods: From the archives of our records, 22 cases with intestinal atresia were reevaluated. The patients' demographic data were noted. Anomalies associated with intestinal atresia were grouped into systemic categories and the main …
Physicians' Attitudes Toward Clinical Ethics Consultation: A Research Study From Turkey, Funda Gülay Kadioğlu, Rana Can, Selda Okuyaz, Si̇bel Öner Yalçin, Nuri̇ Seli̇m Kadioğlu
Physicians' Attitudes Toward Clinical Ethics Consultation: A Research Study From Turkey, Funda Gülay Kadioğlu, Rana Can, Selda Okuyaz, Si̇bel Öner Yalçin, Nuri̇ Seli̇m Kadioğlu
Turkish Journal of Medical Sciences
To identify the reasons why physicians request or do not request ethics consultation and to determine the priority of ethical issues for those demanding consultation. Materials and methods: This survey was conducted using a self-administered questionnaire, and 270 clinicians (surgeons and internists) from 3 different medical school hospitals were included. The questionnaire consisted of Likert-type statements related to the reasons for requesting or not requesting ethics consultation and a ranking list of ethical dilemmas according to the physicians' priorities. Results: Of all clinicians, 40.4% were employed in surgical departments and 59.6% in internal medicine departments. Most of the physicians (90%) …
Risk Factors For Smoking Behavior Among University Students, Sevgi̇ Yurt Öncel, Ömer Lütfi̇ Gebi̇zli̇oğlu, Fazi̇l Ali̇ev Ali̇oğlu
Risk Factors For Smoking Behavior Among University Students, Sevgi̇ Yurt Öncel, Ömer Lütfi̇ Gebi̇zli̇oğlu, Fazi̇l Ali̇ev Ali̇oğlu
Turkish Journal of Medical Sciences
To identify factors associated with increased smoking risks among Kırıkkale University students using a questionnaire. Smoking is a widespread habit in Turkey and a major public health problem in the world. Materials and methods: We assessed 1734 (11.6% of 15,000 total) students (869 males and 866 females, both smokers and nonsmokers) at Kırıkkale University with the questionnaire, which included questions about age, gender, smoking status of student, smoking status and education levels of parents, income, daily sports activities, smoking history (age when started or quit smoking, daily average number of cigarettes smoked, attempts to quit smoking, the reasons for starting …
Neurological Presentations Of Nutritional Vitamin B12 Deficiency In 42 Breastfed Infants In Southeast Turkey, Mustafa Taşkesen, Ahmet Yaramiş, Selahatti̇n Katar, Ayfer Gözü Pi̇ri̇nççi̇oğlu, Murat Söker
Neurological Presentations Of Nutritional Vitamin B12 Deficiency In 42 Breastfed Infants In Southeast Turkey, Mustafa Taşkesen, Ahmet Yaramiş, Selahatti̇n Katar, Ayfer Gözü Pi̇ri̇nççi̇oğlu, Murat Söker
Turkish Journal of Medical Sciences
Nutritional vitamin B12 deficiency is common in developing and underdeveloped countries and has a wide variety of neurological presentations. The aim of this study was to evaluate the neurological characteristics and laboratory results of infants with vitamin B12 deficiency. Materials and methods: A total of 42 infants were included in this study. All patients were evaluated for clinical, physical, and neurological abnormalities, and an attempt was made to obtain short-term neurologic follow-up. Results: Of 42 patients, 24 (57%) were boys and 18 (43%) were girls. The average age at diagnosis was 13.04 ± 5.68 months. Most of these infants were …
Evaluation Of The Effectiveness Of An Intervention Program On Preventing Childhood Obesity In Denizli, Turkey, Özgür Sevi̇nç, Ali̇ İhsan Bozkurt, Mehmet Gündoğdu, Ümmühan Baş Aslan, Bülent Ağbuğa, Şehmus Aslan, Emel Di̇kbaş, Zeli̇ha Gökçe
Evaluation Of The Effectiveness Of An Intervention Program On Preventing Childhood Obesity In Denizli, Turkey, Özgür Sevi̇nç, Ali̇ İhsan Bozkurt, Mehmet Gündoğdu, Ümmühan Baş Aslan, Bülent Ağbuğa, Şehmus Aslan, Emel Di̇kbaş, Zeli̇ha Gökçe
Turkish Journal of Medical Sciences
To determine the efficiency of 2 different intervention programs (healthy nutrition education and/or physical activity programs) for preventing the obesity of primary school students. Materials and methods: Selected were 6 schools, making 3 groups, from all primary schools in Denizli with the half-day education system. Each group was composed of 2 schools. The groups were randomly divided into intervention group 1, intervention group 2, and the control group. The body mass index (BMI) levels of the students in all of the groups were calculated. Both the physical activity and healthy nutrition programs were applied to intervention group 1, and only …
A Practical Calculation Method For Predetermination Of Amount And Duration Of Expander Application, Önder Tan
A Practical Calculation Method For Predetermination Of Amount And Duration Of Expander Application, Önder Tan
Turkish Journal of Medical Sciences
Expander application has become one of the methods most commonly used in reconstructive surgery by virtue of its many advantages. Determination of the amount and duration of expansion completely depends on a surgeon's experience and clinical estimation. Interestingly, no quantitative method has been described in the literature. In an attempt to address this issue, I developed a practical calculation method for expander cases. I use this technique daily during the expansion process to decide whether or not to complete the procedure. By means of this practical method, I believe that expanders can be optimally and more effectively utilized in reconstructive …
The Second Step In Vitro Trial Of Ankaferd® Bloodstopper®: Comparison With Other Hemostatic Agents, Emre Huri̇, Kadi̇r Turgay Akgül, Mehmet Özgür Yücel, Hesna Müzeyyen Astarci, Hüseyi̇n Üstün, Rüştü Cankon Germi̇yanoğlu
The Second Step In Vitro Trial Of Ankaferd® Bloodstopper®: Comparison With Other Hemostatic Agents, Emre Huri̇, Kadi̇r Turgay Akgül, Mehmet Özgür Yücel, Hesna Müzeyyen Astarci, Hüseyi̇n Üstün, Rüştü Cankon Germi̇yanoğlu
Turkish Journal of Medical Sciences
To investigate the efficacy of Ankaferd Bloodstopper (ABS) and compare ABS with the other hemostatic agents still used in urologic surgery. Materials and methods: Forty Wistar rats were divided into 5 groups: Group T (traditional), partial nephrectomy (PN) with hilar control as per the conventional technique; Group G (Glubran 2), conventional PN followed by the application of Glubran 2; Group F (FloSeal), FloSeal application to the resected area of the kidney; Group C (Celox), Celox was applied; Group A (ABS), Ankaferd was used. Warm ischemia time (WIT) and hemostasis time (HT) were recorded and histopathologic features were compared among the …
Şerefeddin Sabuncuoğlu’S Drawings Of Gyneco-Obstetric Instruments, Nuri̇ Seli̇m Kadioğlu, Oya Ögenler, İlter Uzel
Şerefeddin Sabuncuoğlu’S Drawings Of Gyneco-Obstetric Instruments, Nuri̇ Seli̇m Kadioğlu, Oya Ögenler, İlter Uzel
Turkish Journal of Medical Sciences
The purpose of our study was to determine the contribution of Şerefeddin Sabuncuoğlu's achievement to bring gynecology to the modern knowledge level. The gynecological tools in the achievement of Serefeddin Sabuncuoğlu, who is the late period representative of classical medical paradigm, are examined in connection with the achievement of Zahravi, which belongs to the classical medical literature. It was determined that in the long time interval from Zahravi to Sabuncuoğlu a limited advancement occurred in medical knowledge, and that the differences between the achievements of the 2 doctors are important for reflecting the development between the 2 periods.
In Vitro Efficacy Of Different Chemical Substances On Hydatid Cyst Components, Ömer Faruk Akinci, Mustafa Karaoğlanoğlu, Mustafa Sedat Bozkurt, Leyla Gözaydin, Sali̇h Zeki̇ Zi̇ylan
In Vitro Efficacy Of Different Chemical Substances On Hydatid Cyst Components, Ömer Faruk Akinci, Mustafa Karaoğlanoğlu, Mustafa Sedat Bozkurt, Leyla Gözaydin, Sali̇h Zeki̇ Zi̇ylan
Turkish Journal of Medical Sciences
Cyst membrane, daughter cyst, and pericyst are the focal point of some problems related to the percutaneous treatment of hydatid disease. This study was planned to investigate the in vitro efficacy of sodium hypochlorite, hydrogen peroxide, some widely used scolicidal agents, and some chemical solvents on hydatid cyst components. Materials and methods: To investigate the effects of various pharmacological and chemical agents on hydatid cyst components, 5 mL each of 15 different agents was put into bottles. Tissue measuring 2 × 1 cm was cut from the pericyst and the cyst membrane was put into each bottle. Two undamaged daughter …
Single Or Double Sperm Wash Processing By Density Gradient Centrifugation: Effect On Clomiphene Citrate Induced Intrauterine Insemination Cycle Outcomes, Ni̇lgün Turhan, Aslihan Pekel, Yüksel Onaran, Zehra Candan İltemi̇r Duvan, Ömer Bayrak
Single Or Double Sperm Wash Processing By Density Gradient Centrifugation: Effect On Clomiphene Citrate Induced Intrauterine Insemination Cycle Outcomes, Ni̇lgün Turhan, Aslihan Pekel, Yüksel Onaran, Zehra Candan İltemi̇r Duvan, Ömer Bayrak
Turkish Journal of Medical Sciences
To compare the motility yields of single or double wash after density gradient centrifugation of the ejaculate and their effects on pregnancy rates in clomiphene citrate induced intrauterine insemination (IUI) cycles. Materials and methods: This prospective randomized controlled study included 341 IUI cycles. Sperm specimens processed by density gradient centrifugation either with single wash (the single wash group, n = 170) or double wash treatment (the double wash group, n = 171). Sperm parameters before and after the preparation and the cycle outcomes were evaluated. The main outcome measure was the pregnancy rate. Results: The prewash sperm concentrations, the total …
The Optimal Dose Of Vitamin D In Growing Girls During Academic Years: A Randomized Trial, Mehrdad Shakinba, Samane Tefagh, Zahra Nafei
The Optimal Dose Of Vitamin D In Growing Girls During Academic Years: A Randomized Trial, Mehrdad Shakinba, Samane Tefagh, Zahra Nafei
Turkish Journal of Medical Sciences
Prevalence of vitamin D deficiency is remarkable during childhood and adolescence throughout the world. Sufficient intake of vitamin D contributes to a number of health outcomes. The aim of this study was to specify the optimal dose of vitamin D in growing girls in a Muslim country during an academic year. Materials and methods: This randomized clinical trial study was carried out in Yazd in the center of Iran in 2007;120 junior high school girls (aged 12-15 years) were randomly divided into 4 groups. Sixty students in groups I and II were treated for vitamin D deficiency with 300,000 IU …
Effects Of 50 Hz Electric Field On Malondyaldehide And Nitric Oxide Levels In Spinal Cord Of Rats At Prenatal Plus Postnatal Period, Ertuğrul Uzar, Haci Ramazan Yilmaz, Mustafa Yilmaz, Efkan Uz, Vedat Ali̇ Yürekli̇, Bumi̇n Dündar, Hasan Rifat Koyuncuoglu, Selçuk Çömlekçi̇
Effects Of 50 Hz Electric Field On Malondyaldehide And Nitric Oxide Levels In Spinal Cord Of Rats At Prenatal Plus Postnatal Period, Ertuğrul Uzar, Haci Ramazan Yilmaz, Mustafa Yilmaz, Efkan Uz, Vedat Ali̇ Yürekli̇, Bumi̇n Dündar, Hasan Rifat Koyuncuoglu, Selçuk Çömlekçi̇
Turkish Journal of Medical Sciences
The effect of 50 Hz electric field (EF) on developing neural tissues is not known. We aimed to determine whether there would be any oxidative stress effect of 50 Hz EF on developing spinal cord tissues of pup rats by evaluating malondialdehyde (MDA), nitric oxide (NO) levels, and antioxidant enzyme activities such as superoxide dismutase (SOD) and catalase (CAT) measurement. Materials and methods: In the prenatal+postnatal group, the pregnant rat was exposed to continuous EF at 50 Hz 10 kV/s until delivery. Then the female pups of this group (n = 7) were exposed to EF at the same doses …
Adverse Events Associated With Exchange Transfusion And Etiology Of Severe Hyperbilirubinemia In Near-Term And Term Newborns, Ali̇ Bülbül, Feri̇de Füsun Okan, Emel Kabakoğlu Ünsür, Asi̇ye Nuhoğlu
Adverse Events Associated With Exchange Transfusion And Etiology Of Severe Hyperbilirubinemia In Near-Term And Term Newborns, Ali̇ Bülbül, Feri̇de Füsun Okan, Emel Kabakoğlu Ünsür, Asi̇ye Nuhoğlu
Turkish Journal of Medical Sciences
To assess clinical features, etiology, and complications in term and near-term newborns who received exchange transfusion. Materials and methods: Infants with >=35 gestational weeks admitted to our neonatal intensive care unit in the first 30 days of life and underwent exchange transfusion due to severe hyperbilirubinemia between 2002 and 2008 were included. Clinical features, etiology of hyperbilirubinemia, and complications of exchange transfusion were assessed. Results: Exchange transfusion was performed 86 times in a total of 73 patients. Eleven patients received exchange transfusion twice, and 1 patient 3 times. A great proportion of the patients (61.6%) were male, and mean (± …
Urginea Maritima (L.) Baker (Liliaceae) Extract Induces More Cytotoxicity Than Standard Chemotherapeutics In The A549 Non-Small Cell Lung Cancer (Nsclc) Cell Line, Hakan Bozcuk, Mustafa Özdoğan, Oktay Aykurt, Fati̇h Topçuoğlu, Hasan Öztürk, Deni̇z Eki̇nci̇, Asuman Karadeni̇z, Ayli̇n Mutlu, Durmuş Burgucu
Urginea Maritima (L.) Baker (Liliaceae) Extract Induces More Cytotoxicity Than Standard Chemotherapeutics In The A549 Non-Small Cell Lung Cancer (Nsclc) Cell Line, Hakan Bozcuk, Mustafa Özdoğan, Oktay Aykurt, Fati̇h Topçuoğlu, Hasan Öztürk, Deni̇z Eki̇nci̇, Asuman Karadeni̇z, Ayli̇n Mutlu, Durmuş Burgucu
Turkish Journal of Medical Sciences
Urginea maritima (Um) is a plant native to especially Turkey and the Mediterranean area. In this study, we investigated whether Um extract exerted cytotoxicity on cancer cells. Materials and methods: We made various extracts of Um. These extracts in varying concentrations were added to an A549 NSCLC cell culture, alone or with gemcitabine and/or cisplatin. Growth inhibition was tested by the MTT assay and an Annexin V-FITC apoptosis detection kit Results: The onion Um extract (1 µg/mL) was more cytotoxic than cisplatin (1 µg/mL), gemcitabine (1 nm/mL), and leaf Um extract (1 µg/mL) with P < 0.001, P = 0.097, and P < 0.001, respectively. The efficacy of Um extract was further improved by the addition of an antioxidant cocktail to an IC_{50} value of 0.02 µg/mL. Conclusion: Um extract has been shown for the first time to be a strong candidate for drug development in solid tumors. Our studies continue to further define the specific antitumor compound(s) in this extract.
Evaluation Of Gdx Parameters By Using Information Theory, Umut Arslan, Banu Bozkurt, Ahmet Ergun Karaağaoğlu, Murat Tanju İrkeç
Evaluation Of Gdx Parameters By Using Information Theory, Umut Arslan, Banu Bozkurt, Ahmet Ergun Karaağaoğlu, Murat Tanju İrkeç
Turkish Journal of Medical Sciences
To evaluate the performance of GDx parameters in the diagnosis of glaucoma by using information theory and compare the results obtained using receiver operating characteristic (ROC) curve analysis, which is a traditional method. Materials and methods: Retinal nerve fiber layer thickness was measured in 270 eyes with glaucoma and 81 normal eyes with scanning laser polarimeter (NFA GDx version, 1.0.08), and 14 GDx parameters were calculated. Both ROC curve analysis and information theory were used to determine the best GDx parameters. The best cut-off points of these parameters were obtained using information theory for glaucoma prevalence (Pr) of 1%, 2%, …
Which Predicts The Cardiovascular Risk Best In Elderly Metabolic Syndrome Patients: Atp Iii Or Idf?, Serpi̇l Aydin, Ayfer Gemalmaz, Tufan Nayi̇r, Şule Özkan
Which Predicts The Cardiovascular Risk Best In Elderly Metabolic Syndrome Patients: Atp Iii Or Idf?, Serpi̇l Aydin, Ayfer Gemalmaz, Tufan Nayi̇r, Şule Özkan
Turkish Journal of Medical Sciences
As metabolic syndrome (MetS) is one of the major determinants of cardiovascular disease, it is important to detect and intervene with MetS in order to minimize cardiovascular risk. The objectives of this study were to identify the prevalence of MetS in our elderly patients and to evaluate the ability IDF and ATP III to predict the cardiovascular risk. Materials and methods: This cross-sectional study included patients above 65 years attending the outpatient clinic of a hospital over a 4-year period and who gave oral informed consent for participation in the study. ATP III and IDF criteria were compared according to …
Invasive Device-Associated Nosocomial Infections Of A Teaching Hospital In Turkey; Four Years’ Experience, Aslihan Candevi̇r, Behi̇ce Kurtaran, Fi̇li̇z Ki̇bar, Emre Karakoç, Hasan Sali̇h Zeki̇ Aksu, Yeşi̇m Taşova
Invasive Device-Associated Nosocomial Infections Of A Teaching Hospital In Turkey; Four Years’ Experience, Aslihan Candevi̇r, Behi̇ce Kurtaran, Fi̇li̇z Ki̇bar, Emre Karakoç, Hasan Sali̇h Zeki̇ Aksu, Yeşi̇m Taşova
Turkish Journal of Medical Sciences
To determine our setting's IDAI rates, infecting microorganisms, and their resistance patterns to achieve standardization and make comparisons among other Turkish and developed country hospitals all over the world. Materials and methods: The numbers of total patient days, ventilator days, central catheter days and, urinary catheter days in the ICUs were recorded and IDAI rates were calculated. Clinical specimens were obtained from patients, cultivated at appropriate culture media, and infecting microorganisms and resistance patterns were determined. Results: Totally 1450 invasive device-associated infection episodes were determined (16.4% of patients) with a rate of 21.12/1000 days. Ventilator associated pneumonia rate was 22.05/1000 …
Relationship Between Pon1 Phenotype And Headache Duration In Migraine Patients, Şahbetti̇n Selek, Recep Alp, Selen İlhan Alp, Abdullah Taşkin
Relationship Between Pon1 Phenotype And Headache Duration In Migraine Patients, Şahbetti̇n Selek, Recep Alp, Selen İlhan Alp, Abdullah Taşkin
Turkish Journal of Medical Sciences
The available data on the activity of paraoxonase-1 (PON1) in patients suffering from migraine without aura (MWoA) is scarce. The present study was conducted to fulfill the objective of investigating the probability of an association between PON1 phenotype distribution and headache duration in patients suffering from MWoA. Materials and methods: Seventy-six patients who suffer from MWoA and were not experiencing attacks at the time and 65 healthy volunteers were enrolled for the purpose of evaluation in the present study. Results: The levels of serum paraoxonase, arylesterase activities, and lipid hydroperoxide (LOOH) were determined for these subjects. The results obtained revealed …
Serum Paraoxonase And Arylesterase Activities In Iron Deficiency Anemia During Pregnancy, Hakan Camuzcuoğlu, Harun Toy, Mehmet Vural, Aysun Camuzcuoğlu, Abdullah Taşkin, Haki̇m Çeli̇k
Serum Paraoxonase And Arylesterase Activities In Iron Deficiency Anemia During Pregnancy, Hakan Camuzcuoğlu, Harun Toy, Mehmet Vural, Aysun Camuzcuoğlu, Abdullah Taşkin, Haki̇m Çeli̇k
Turkish Journal of Medical Sciences
To investigate serum paraoxonase and arylesterase activities, and lipid hydroperoxide levels in pregnant women with iron deficiency anemia. Materials and methods: Paraoxonase and arylesterase activities, and lipid hydroperoxide levels were assessed for pregnant women with iron deficiency anemia (n = 50) and controls (n = 70). Serum basal and salt-stimulated paraoxonase, and arylesterase activities were measured spectrophotometrically. The lipid hydroperoxide levels were measured by ferrous ion oxidation xylenol orange assay. In addition, lipid parameters were determined by routine laboratory methods. Results: Basal and salt-stimulated paraoxonase, and arylesterase activities were significantly lower (P = 0.026, P = 0.031, and P = …
The Cytomorphological Analysis Of Buccal Mucosa Cells In Smokers, Mustafa Göregen, Hayati̇ Murat Akgül, Cemal Gündoğdu
The Cytomorphological Analysis Of Buccal Mucosa Cells In Smokers, Mustafa Göregen, Hayati̇ Murat Akgül, Cemal Gündoğdu
Turkish Journal of Medical Sciences
To examine the effect of smoking on normal buccal mucosa cytomorphologically. Materials and methods: Forty individuals aged between 40 and 60, comprising 23 smokers (14 male, 9 female) and 17 and non-smokers (10 male, 7 female), were included in the study. The buccal epithelial cells of these individuals were collected with a brush and the cells were measured cytomorphometrically using software. Results: The average nuclear area (NA), nuclear perimeter (NP), minimal nuclear diameter (D-min), and maximal nuclear diameter (D-max) were 46.00 ± 11.31, 28.18 ± 2.43, 6.18 ± 0.88, and 10.00 ± 0.94, respectively, in the control group, and 53.61 …
In Vitro Effect Of Resveratrol Against Oxidative Injury Of Human Coronary Artery Endothelial Cells, Oya Sayin, Nur Arslan, Zeki̇ye Sultan Altun, Gül Akdoğan
In Vitro Effect Of Resveratrol Against Oxidative Injury Of Human Coronary Artery Endothelial Cells, Oya Sayin, Nur Arslan, Zeki̇ye Sultan Altun, Gül Akdoğan
Turkish Journal of Medical Sciences
Reactive oxygen species induce oxidative stress that may contribute to endothelial dysfunction. In addition to endogen antioxidants, adding antioxidants to diet has been used to reduce oxidative-stress-induced endothelial dysfunction. Resveratrol is a natural phytoalexin which has many effects including antioxidant activity. The aim of this study was to investigate whether resveratrol could protect human coronary artery endothelial cells against in vitro oxidative-stress-mediated injury. Materials and methods: Human coronary artery endothelial cells were treated with varying concentrations of hydrogen peroxide for different durations and hydrogen peroxide plus varying concentrations of resveratrol. Then cell death was measured using lactate dehydrogenase release. Human …
The Role Of Red Cell Distribution Width As A Marker In Inflammatory Bowel Disease, Mehmet Arhan, İbrahi̇m Koral Önal, Adnan Taş, Mevlüt Kurt, İsmai̇l Hakki Kalkan, Yasemi̇n Özi̇n, Bi̇lge Tunç, Aysel Ülker
The Role Of Red Cell Distribution Width As A Marker In Inflammatory Bowel Disease, Mehmet Arhan, İbrahi̇m Koral Önal, Adnan Taş, Mevlüt Kurt, İsmai̇l Hakki Kalkan, Yasemi̇n Özi̇n, Bi̇lge Tunç, Aysel Ülker
Turkish Journal of Medical Sciences
To determine whether red cell distribution width could be used for the assessment of disease activity in patients with inflammatory bowel disease. Materials and methods: A total of 165 patients with inflammatory bowel disease (105 ulcerative colitis; 60 Crohn's disease) and 43 healthy blood donors were included in this retrospective study in a tertiary care setting. The medical records of the patients were reviewed to note clinical activity indices, red cell distribution width, serum C reactive protein, erythrocyte sedimentation rates, leukocyte, and platelet counts. Results: Red cell distribution width, serum C reactive protein, erythrocyte sedimentation rate, platelet count, and the …
Immunomodulatory Role Of Leptin Treatment In Experimental Sepsis Caused By Gram Negative Bacteria, Cemi̇le Koca, Havva Şahi̇n Kavakli, Özlem Alici
Immunomodulatory Role Of Leptin Treatment In Experimental Sepsis Caused By Gram Negative Bacteria, Cemi̇le Koca, Havva Şahi̇n Kavakli, Özlem Alici
Turkish Journal of Medical Sciences
To investigate the effect of leptin treatment on circulating inflammatory cytokines and on tissue damage in experimental rat model of gram-negative sepsis. Materials and methods: Adult male Wistar rats, 28 in total, were randomly divided into 4 groups (n = 7): sham, leptin, sepsis, and sepsis group treated with leptin (sepsis+leptin). Sepsis was induced by intraperitoneal (ip) injection of 2 × 10^{10} CFU of Escherichia coli ATCC 25922. Leptin and sepsis+leptin groups received a single dose ip 0.1 mg/kg leptin, while sham group received 1 mL of ip saline. Rats were sacrificed 24 h after the induction of sepsis. Blood …
Glutamate Dehydrogenase And Triose-Phosphate-Isomerase Coding Genes For Detection And Genetic Characterization Of Giardia Lamblia In Human Feces By Pcr And Pcr-Rflp*, Kareem Hatam Nahavandi, Esmaeel Fallah, Mohammad Asgharzadeh, Nasrin Mirsamadi, Behroz Mahdavipour
Glutamate Dehydrogenase And Triose-Phosphate-Isomerase Coding Genes For Detection And Genetic Characterization Of Giardia Lamblia In Human Feces By Pcr And Pcr-Rflp*, Kareem Hatam Nahavandi, Esmaeel Fallah, Mohammad Asgharzadeh, Nasrin Mirsamadi, Behroz Mahdavipour
Turkish Journal of Medical Sciences
The purpose of this study was comparison of the glutamate dehydrogenase (gdh) and triose phosphate isomerase (tpi) genes for detection and genetic characterization of Giardia lamblia (G. lamblia) in human stool by polymerase chain reaction (PCR) and PCR-restriction fragment length polymorphism (RFLP). Our assay was specific and distinguished between G. lamblia assemblages A and B. Materials and methods: Among the 325 stool samples obtained from patients with acute gastroenteritis hospitalized in the Pediatric Hospital and infected humans referred to the Tabriz Reference Laboratory (TRL), 34 Giardia-positive stool samples were identified by conventional techniques. Two assays-PCR and PCR-RFLP-targeting the tpi and …